Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Receptors, Death Domain MeSH Descriptor Data 2025


MeSH Heading
Receptors, Death Domain
Tree Number(s)
D12.776.543.750.690
Unique ID
D053218
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053218
Scope Note
A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.
Entry Version
RECEPT DEATH DOMAIN
Entry Term(s)
Death Domain Receptors
Death Receptor
Death Receptors
Receptors, DR Family
Receptors, Death Domain Family
Registry Numbers
0
See Also
Receptors, Tumor Necrosis Factor
Public MeSH Note
2007
History Note
2007
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2020/05/27
Receptors, Death Domain Preferred
page delivered in 0.149s