MeSH Browser

MeSH Heading: Eukaryotic Initiation Factor-4A
Tree Number(s): D08.811.913.696.445.735.720.500; D12.776.835.725.868.500.500
Unique ID: D039601
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D039601
Scope Note: A component of eukaryotic initiation factor 4F that as an RNA helicase involved in unwinding the secondary structure of the 5' UNTRANSLATED REGION of MRNA. The unwinding facilitates the binding of the 40S ribosomal subunit.
Entry Term(s): EIF-4A; EIF-4A1; EIF-4A2; EIF-4A3; EIF4AIII; Eukaryotic Initiation Factor EIF-4A; Eukaryotic Initiation Factor-4A1; Eukaryotic Initiation Factor-4A2; Eukaryotic Initiation Factor-4A3; Eukaryotic Peptide Initiation Factor-4A; Eukaryotic Translation-Initiation Factor 4AIII; Peptide Initiation Factor EIF-4A
Registry Numbers: EC 2.7.7.-; 0
Previous Indexing: Peptide Initiation Factors (1980-2002)
Public MeSH Note: 2003; EIF-4A (now EUKARYOTIC INITIATION FACTOR-4A) was indexed under PEPTIDE INITIATION FACTORS 1980-2002
History Note: 2003; use EUKARYOTIC INITIATION FACTOR-F4A (NM) 1980-2001
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0086510
Registry Numbers: EC 2.7.7.-
Scope Note: A component of eukaryotic initiation factor 4F that as an RNA helicase involved in unwinding the secondary structure of the 5' UNTRANSLATED REGION of MRNA. The unwinding facilitates the binding of the 40S ribosomal subunit.
Terms: Eukaryotic Initiation Factor-4A Preferred Term
Term UI T488241
Date04/01/2002
LexicalTag NON
ThesaurusID NLM (2003); Eukaryotic Initiation Factor EIF-4A
Term UI T116512
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); EIF-4A
Term UI T116513
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2003); Peptide Initiation Factor EIF-4A
Term UI T489280
Date04/12/2002
LexicalTag ACX
ThesaurusID NLM (2003); Eukaryotic Peptide Initiation Factor-4A
Term UI T489281
Date04/12/2002
LexicalTag NON
ThesaurusID NLM (2003)

Concept UI: M0350427
Registry Numbers: 0
Terms: Eukaryotic Initiation Factor-4A3 Preferred Term
Term UI T488943
Date04/08/2002
LexicalTag ACX
ThesaurusID NLM (2003); EIF4AIII
Term UI T400641
Date11/23/1999
LexicalTag ACR
ThesaurusID NLM (2003); Eukaryotic Translation-Initiation Factor 4AIII
Term UI T400642
Date11/23/1999
LexicalTag ACX
ThesaurusID NLM (2003); EIF-4A3
Term UI T400643
Date11/23/1999
LexicalTag ACR
ThesaurusID NLM (2003)

Eukaryotic Initiation Factor-4A MeSH Descriptor Data 2025