MeSH Browser

MeSH Supplementary: Diabetes Mellitus, Permanent Neonatal
Unique ID: C563425
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C563425
Entry Term(s): Diabetes Mellitus, Permanent, of Infancy; Permanent Neonatal Diabetes Mellitus
Registry Number: 0
Heading Mapped to: *Diabetes Mellitus
Frequency: 112
Note: A rare autosomal dominant genetically heterogeneous hereditary form of diabetes mellitus which is distinct from Type I diabetes mellitus and affected individuals present with insulin-requiring hyperglycemia within the first 3 months of life. About 50% of cases resolve by 3 months but may later develop type II diabetes. The cases that do not resolve develop permanent insulin-dependent diabetes and many also have neurologic and morphologic abnormalities. Mutations in the GCK, KCNJ11, ABCC8, and INS genes have been identified. OMIM: 606176
Date of Entry: 2012/11/05
Revision Date: 2015/08/18

Diabetes Mellitus, Permanent Neonatal MeSH Supplementary Concept Data 2024