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Showing metabocard for Selenomethionine (HMDB0003966)

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Record Information
Version5.0
StatusDetected and Quantified
Creation Date2006-08-13 08:10:37 UTC
Update Date2023-02-21 17:16:51 UTC
HMDB IDHMDB0003966
Secondary Accession Numbers
  • HMDB03966
Metabolite Identification
Common NameSelenomethionine
DescriptionSelenomethionine (CAS: 1464-42-2) is an amino acid containing selenium that cannot be synthesized by higher animals but can be obtained from plant material. Selenomethionine is the major seleno-compound in cereal grains (wheat grain, maize, and rice), soybeans, and enriched yeast. Seleno-compounds present in plants may have a profound effect on the health of animals and human subjects. It is now known that the total Se content cannot be used as an indication of its efficacy, but knowledge of individual selenocompounds is necessary to fully assess the significance. Thus, speciation of the seleno-compounds has moved to the forefront. Since animals and man are dependent upon plants for their nutritional requirements, this makes the types of seleno-compounds in plants even more critical. Se enters the food chain through incorporation into plant proteins, mostly as selenocysteine and selenomethionine at normal Se levels. There are two possible pathways for the catabolism of selenomethionine. One is the transsulfuration pathway via selenocystathionine to produce selenocysteine, which in turn is degraded into H2Se by the enzyme beta-lyase. The other pathway is the transamination-decarboxylation pathway. It was estimated that 90% of methionine is metabolized through this pathway and thus could be also the major route for selenomethionine catabolism (PMID:14748935 ).
Structure
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MOL3D MOLSDF3D SDFPDB3D PDBSMILESInChI

MOL for HMDB0003966 (Selenomethionine)

 
  Mrv1652309042000302D          

  9  8  0  0  1  0            999 V2000
   31.2511  -25.1991    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   31.9622  -24.7808    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   30.4982  -24.7808    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   31.2511  -26.0357    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   32.6733  -25.1991    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   29.7871  -25.1991    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   30.4982  -23.9442    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   33.4262  -24.7808    0.0000 Se  0  0  0  0  0  0  0  0  0  0  0  0
   34.1338  -25.2050    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  1  3  1  0  0  0  0
  1  4  1  6  0  0  0
  2  5  1  0  0  0  0
  3  6  1  0  0  0  0
  3  7  2  0  0  0  0
  5  8  1  0  0  0  0
  8  9  1  0  0  0  0
M  END
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3D MOL for HMDB0003966 (Selenomethionine)

HMDB0003966
     RDKit          3D
Selenomethionine
 20 19  0  0  0  0  0  0  0  0999 V2000
    3.7621   -0.3677   -1.3207 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5754    0.0488    0.1446 Se  0  0  0  0  0  2  0  0  0  0  0  0
    0.6973   -0.1232   -0.4088 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1356    0.2581    0.7879 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6143    0.1763    0.5209 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.9949   -1.1570    0.1535 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0749    1.1876   -0.4629 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8630    2.4057   -0.3563 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7848    0.7320   -1.5654 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7285   -0.7984   -0.9647 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0408    0.5911   -1.8404 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3027   -1.0715   -2.0591 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5549   -1.1748   -0.6789 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5535    0.5222   -1.2701 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0906   -0.4328    1.6202 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1233    1.2732    1.1209 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1258    0.4136    1.4824 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8095   -1.5106    0.7051 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2324   -1.8551    0.2790 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7939    0.8824   -1.6595 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  5  7  1  0
  7  8  2  0
  7  9  1  0
  1 10  1  0
  1 11  1  0
  1 12  1  0
  3 13  1  0
  3 14  1  0
  4 15  1  0
  4 16  1  0
  5 17  1  1
  6 18  1  0
  6 19  1  0
  9 20  1  0
M  END
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3D SDF for HMDB0003966 (Selenomethionine)

 
  Mrv1652309042000302D          

  9  8  0  0  1  0            999 V2000
   31.2511  -25.1991    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   31.9622  -24.7808    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   30.4982  -24.7808    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   31.2511  -26.0357    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   32.6733  -25.1991    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   29.7871  -25.1991    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   30.4982  -23.9442    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   33.4262  -24.7808    0.0000 Se  0  0  0  0  0  0  0  0  0  0  0  0
   34.1338  -25.2050    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  1  3  1  0  0  0  0
  1  4  1  6  0  0  0
  2  5  1  0  0  0  0
  3  6  1  0  0  0  0
  3  7  2  0  0  0  0
  5  8  1  0  0  0  0
  8  9  1  0  0  0  0
M  END
> <DATABASE_ID>
HMDB0003966

> <DATABASE_NAME>
hmdb

> <SMILES>
C[Se]CC[C@H](N)C(O)=O

> <INCHI_IDENTIFIER>
InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

> <INCHI_KEY>
RJFAYQIBOAGBLC-BYPYZUCNSA-N

> <FORMULA>
C5H11NO2Se

> <MOLECULAR_WEIGHT>
196.11

> <EXACT_MASS>
196.995500429

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_ATOM_COUNT>
20

> <JCHEM_AVERAGE_POLARIZABILITY>
14.638357525870418

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
2

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2S)-2-amino-4-(methylselanyl)butanoic acid

> <ALOGPS_LOGP>
-2.46

> <JCHEM_LOGP>
-3.3019949587229283

> <ALOGPS_LOGS>
-0.25

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
1.5595213885250407

> <JCHEM_PKA_STRONGEST_BASIC>
9.502319448582847

> <JCHEM_POLAR_SURFACE_AREA>
63.31999999999999

> <JCHEM_REFRACTIVITY>
42.90740000000001

> <JCHEM_ROTATABLE_BOND_COUNT>
4

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
1.09e+02 g/l

> <JCHEM_TRADITIONAL_IUPAC>
L-selenomethionine

> <JCHEM_VEBER_RULE>
0

$$$$
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3D-SDF for HMDB0003966 (Selenomethionine)

HMDB0003966
     RDKit          3D
Selenomethionine
 20 19  0  0  0  0  0  0  0  0999 V2000
    3.7621   -0.3677   -1.3207 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.5754    0.0488    0.1446 Se  0  0  0  0  0  2  0  0  0  0  0  0
    0.6973   -0.1232   -0.4088 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1356    0.2581    0.7879 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6143    0.1763    0.5209 C   0  0  2  0  0  0  0  0  0  0  0  0
   -1.9949   -1.1570    0.1535 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0749    1.1876   -0.4629 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8630    2.4057   -0.3563 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.7848    0.7320   -1.5654 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.7285   -0.7984   -0.9647 H   0  0  0  0  0  0  0  0  0  0  0  0
    4.0408    0.5911   -1.8404 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.3027   -1.0715   -2.0591 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5549   -1.1748   -0.6789 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5535    0.5222   -1.2701 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0906   -0.4328    1.6202 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.1233    1.2732    1.1209 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1258    0.4136    1.4824 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8095   -1.5106    0.7051 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.2324   -1.8551    0.2790 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.7939    0.8824   -1.6595 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  6  1  0
  5  7  1  0
  7  8  2  0
  7  9  1  0
  1 10  1  0
  1 11  1  0
  1 12  1  0
  3 13  1  0
  3 14  1  0
  4 15  1  0
  4 16  1  0
  5 17  1  1
  6 18  1  0
  6 19  1  0
  9 20  1  0
M  END
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PDB for HMDB0003966 (Selenomethionine)

HEADER    PROTEIN                                 04-SEP-20   NONE
TITLE     NULL                                                        
COMPND    MOLECULE:                                                   
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   04-SEP-20         0                                  
HETATM    1  C   UNK     0      58.335 -47.038   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      59.663 -46.257   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      56.930 -46.257   0.000  0.00  0.00           C+0
HETATM    4  N   UNK     0      58.335 -48.600   0.000  0.00  0.00           N+0
HETATM    5  C   UNK     0      60.990 -47.038   0.000  0.00  0.00           C+0
HETATM    6  O   UNK     0      55.603 -47.038   0.000  0.00  0.00           O+0
HETATM    7  O   UNK     0      56.930 -44.696   0.000  0.00  0.00           O+0
HETATM    8 Se   UNK     0      62.396 -46.257   0.000  0.00  0.00          Se+0
HETATM    9  C   UNK     0      63.716 -47.049   0.000  0.00  0.00           C+0
CONECT    1    2    3    4                                                  
CONECT    2    1    5                                                       
CONECT    3    1    6    7                                                  
CONECT    4    1                                                            
CONECT    5    2    8                                                       
CONECT    6    3                                                            
CONECT    7    3                                                            
CONECT    8    5    9                                                       
CONECT    9    8                                                            
MASTER        0    0    0    0    0    0    0    0    9    0   16    0
END
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3D PDB for HMDB0003966 (Selenomethionine)

COMPND    HMDB0003966
HETATM    1  C1  UNL     1       3.762  -0.368  -1.321  1.00  0.00           C  
HETATM    2 SE1  UNL     1       2.575   0.049   0.145  1.00  0.00          SE  
HETATM    3  C2  UNL     1       0.697  -0.123  -0.409  1.00  0.00           C  
HETATM    4  C3  UNL     1      -0.136   0.258   0.788  1.00  0.00           C  
HETATM    5  C4  UNL     1      -1.614   0.176   0.521  1.00  0.00           C  
HETATM    6  N1  UNL     1      -1.995  -1.157   0.154  1.00  0.00           N  
HETATM    7  C5  UNL     1      -2.075   1.188  -0.463  1.00  0.00           C  
HETATM    8  O1  UNL     1      -1.863   2.406  -0.356  1.00  0.00           O  
HETATM    9  O2  UNL     1      -2.785   0.732  -1.565  1.00  0.00           O  
HETATM   10  H1  UNL     1       4.728  -0.798  -0.965  1.00  0.00           H  
HETATM   11  H2  UNL     1       4.041   0.591  -1.840  1.00  0.00           H  
HETATM   12  H3  UNL     1       3.303  -1.072  -2.059  1.00  0.00           H  
HETATM   13  H4  UNL     1       0.555  -1.175  -0.679  1.00  0.00           H  
HETATM   14  H5  UNL     1       0.554   0.522  -1.270  1.00  0.00           H  
HETATM   15  H6  UNL     1       0.091  -0.433   1.620  1.00  0.00           H  
HETATM   16  H7  UNL     1       0.123   1.273   1.121  1.00  0.00           H  
HETATM   17  H8  UNL     1      -2.126   0.414   1.482  1.00  0.00           H  
HETATM   18  H9  UNL     1      -2.809  -1.511   0.705  1.00  0.00           H  
HETATM   19  H10 UNL     1      -1.232  -1.855   0.279  1.00  0.00           H  
HETATM   20  H11 UNL     1      -3.794   0.882  -1.659  1.00  0.00           H  
CONECT    1    2   10   11   12
CONECT    2    3
CONECT    3    4   13   14
CONECT    4    5   15   16
CONECT    5    6    7   17
CONECT    6   18   19
CONECT    7    8    8    9
CONECT    9   20
END
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SMILES for HMDB0003966 (Selenomethionine)

C[Se]CC[C@H](N)C(O)=O
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INCHI for HMDB0003966 (Selenomethionine)

InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
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View in JSmolView NMR AssignmentsView Stereo Labels
Synonyms
ValueSource
Selenomethionine, (+,-)-isomerHMDB
Selenomethionine se 75HMDB
RadioselenomethionineHMDB
Selenomethionine, (S)-isomerHMDB
SethotopeHMDB
Se 75, selenomethionineHMDB
Selenomethionine hydrochloride, (S)-isomerHMDB
(2S)-2-Amino-4-(methylseleno)butanoic acidHMDB
(2S)-2-Azaniumyl-4-methylselanylbutanoateHMDB
L-SelenomethionineHMDB
Seleno-L-methionineHMDB
2-Amino-4-(methylseleno)butanoic acidHMDB
2-Amino-4-(methylseleno)butyric acidHMDB
2-Amino-4-(methylselenyl)butyric acidHMDB
Selenium methionineHMDB
SelenomethionineMeSH
Chemical FormulaC5H11NO2Se
Average Molecular Weight196.11
Monoisotopic Molecular Weight196.995500429
IUPAC Name(2S)-2-amino-4-(methylselanyl)butanoic acid
Traditional NameL-selenomethionine
CAS Registry Number3211-76-5
SMILES
C[Se]CC[C@H](N)C(O)=O
InChI Identifier
InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChI KeyRJFAYQIBOAGBLC-BYPYZUCNSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassAmino acids, peptides, and analogues
Direct ParentL-alpha-amino acids
Alternative Parents
Substituents
  • L-alpha-amino acid
  • Fatty acid
  • Amino acid
  • Carboxylic acid
  • Monocarboxylic acid or derivatives
  • Selenoether
  • Amine
  • Hydrocarbon derivative
  • Organic oxide
  • Organopnictogen compound
  • Primary amine
  • Organoselenium compound
  • Organooxygen compound
  • Organonitrogen compound
  • Organic oxygen compound
  • Primary aliphatic amine
  • Organic nitrogen compound
  • Carbonyl group
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Ontology
Physiological effectNot Available
Disposition
Biological locationSource
Process
Naturally occurring process
Role
Industrial application
Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting Point275 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
Predicted Chromatographic Properties
Spectra
Biological Properties
Cellular Locations
  • Cytoplasm (predicted from logP)
Biospecimen Locations
  • Blood
  • Urine
Tissue Locations
  • Fibroblasts
  • Kidney
  • Pancreas
  • Prostate
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected and Quantified0.69 (0.56 - 0.82) uMAdult (>18 years old)Not Specified
Normal		 details
BloodDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothNormal details
UrineDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothNormal details
UrineDetected and Quantified0 - 0.002 umol/mmol creatinineAdult (>18 years old)Not SpecifiedNormal details
Abnormal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected and Quantified0.303 +/- 0.099 uMAdult (>18 years old)Not SpecifiedProstate cancer details
Associated Disorders and Diseases
Disease References
Prostate cancer
  1. Nyman DW, Suzanne Stratton M, Kopplin MJ, Dalkin BL, Nagle RB, Jay Gandolfi A: Selenium and selenomethionine levels in prostate cancer patients. Cancer Detect Prev. 2004;28(1):8-16. [PubMed:15041072 ]
Associated OMIM IDs
DrugBank IDDB11142
Phenol Explorer Compound IDNot Available
FooDB IDFDB012156
KNApSAcK IDNot Available
Chemspider IDNot Available
KEGG Compound IDC05335
BioCyc IDSELENOMETHIONINE
BiGG IDNot Available
Wikipedia LinkSelenomethionine
METLIN IDNot Available
PubChem Compound105024
PDB IDNot Available
ChEBI ID30021
Food Biomarker OntologyNot Available
VMH IDSELMETH
MarkerDB IDMDB00000436
Good Scents IDNot Available
References
Synthesis ReferenceJakubke, Hans D.; Fischer, J.; Jost, Karel; Rudinger, Josef. Amino acids and peptides. LXXXVI. Synthesis of L-selenomethionine, L-selenoethionine, and their tert-butoxy-carbonyl derivatives. Collection of Czechoslovak Chemical Communications (1968), 33(11), 3910-12.
Material Safety Data Sheet (MSDS)Not Available
General References

Enzymes

Enzyme Details
1. Methionine synthase
General function:
Involved in cobalamin binding
Specific function:
Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity).
Gene Name:
MTR
Uniprot ID:
Q99707
Molecular weight:
140525.91
Reactions
Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamic acid → Selenomethionine + Tetrahydropteroyltri-L-glutamic aciddetails
Enzyme Details
2. S-adenosylmethionine synthase isoform type-2
General function:
Involved in methionine adenosyltransferase activity
Specific function:
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
Gene Name:
MAT2A
Uniprot ID:
P31153
Molecular weight:
43660.37
Reactions
Adenosine triphosphate + Selenomethionine + Water → Phosphate + Pyrophosphate + Se-Adenosylselenomethioninedetails
Enzyme Details
3. S-adenosylmethionine synthase isoform type-1
General function:
Involved in methionine adenosyltransferase activity
Specific function:
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
Gene Name:
MAT1A
Uniprot ID:
Q00266
Molecular weight:
43647.6
Reactions
Adenosine triphosphate + Selenomethionine + Water → Phosphate + Pyrophosphate + Se-Adenosylselenomethioninedetails
Enzyme Details
4. Cystathionine gamma-lyase
General function:
Involved in pyridoxal phosphate binding
Specific function:
Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.
Gene Name:
CTH
Uniprot ID:
P32929
Molecular weight:
41259.91
Reactions
Selenomethionine + Water → Methaneselenol + Ammonia + 2-Ketobutyric aciddetails
Enzyme Details
5. Methionine--tRNA ligase, cytoplasmic
General function:
Involved in nucleotide binding
Specific function:
Not Available
Gene Name:
MARS
Uniprot ID:
P56192
Molecular weight:
101114.925
Reactions
Adenosine triphosphate + Selenomethionine + tRNA(Met) → Adenosine monophosphate + Pyrophosphate + Selenomethionyl-tRNA(Met)details
Enzyme Details
6. Methionine adenosyltransferase 2 subunit beta
General function:
Involved in dTDP-4-dehydrorhamnose reductase activity
Specific function:
Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition.
Gene Name:
MAT2B
Uniprot ID:
Q9NZL9
Molecular weight:
Not Available
Reactions
Adenosine triphosphate + Selenomethionine + Water → Phosphate + Pyrophosphate + Se-Adenosylselenomethioninedetails
Enzyme Details
7. Methionine--tRNA ligase, mitochondrial
General function:
Involved in nucleotide binding
Specific function:
Not Available
Gene Name:
MARS2
Uniprot ID:
Q96GW9
Molecular weight:
66590.29
Reactions
Adenosine triphosphate + Selenomethionine + tRNA(Met) → Adenosine monophosphate + Pyrophosphate + Selenomethionyl-tRNA(Met)details