| Record Information |
|---|
| Version | 5.0 |
|---|
| Status | Detected and Quantified |
|---|
| Creation Date | 2005-11-16 15:48:42 UTC |
|---|
| Update Date | 2023-02-21 17:14:33 UTC |
|---|
| HMDB ID | HMDB0000143 |
|---|
| Secondary Accession Numbers | - HMDB0005762
- HMDB00143
- HMDB05762
|
|---|
| Metabolite Identification |
|---|
| Common Name | D-Galactose |
|---|
| Description | D-Galactose (CAS: 59-23-4) is an aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. D-Galactose is an energy-providing nutrient and also a necessary basic substrate for the biosynthesis of many macromolecules in the body. Metabolic pathways for D-galactose are important not only for the provision of these pathways but also for the prevention of D-galactose metabolite accumulation. The main source of D-galactose is lactose in the milk of mammals, but it can also be found in some fruits and vegetables. Utilization of D-galactose in all living cells is initiated by the phosphorylation of the hexose by the enzyme galactokinase (E.C. 2.7.1.6) (GALK) to form D-galactose-1-phosphate. In the presence of D-galactose-1-phosphate uridyltransferase (E.C. 2.7.7.12) (GALT) D-galactose-1-phosphate is exchanged with glucose-1-phosphate in UDP-glucose to form UDP-galactose. Glucose-1-phosphate will then enter the glycolytic pathway for energy production. Deficiency of the enzyme GALT in galactosemic patients leads to the accumulation of D-galactose-1-phosphate. Classic galactosemia, a term that denotes the presence of D-galactose in the blood, is the rare inborn error of D-galactose metabolism, diagnosed by the deficiency of the second enzyme of the D-galactose assimilation pathway, GALT, which, in turn, is caused by mutations at the GALT gene (PMID: 15256214 , 11020650 , 10408771 ). Galactose in the urine is a biomarker for the consumption of milk. |
|---|
| Structure | OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6+/m1/s1 |
|---|
| Synonyms | | Value | Source |
|---|
| ALPHA D-GALACTOSE | ChEBI | | alpha-D-Gal | ChEBI | | Gal-alpha | ChEBI | | alpha-D-Galactose | Kegg | | a D-GALACTOSE | Generator | | Α D-galactose | Generator | | a-D-Gal | Generator | | Α-D-gal | Generator | | Gal-a | Generator | | Gal-α | Generator | | a-D-Galactose | Generator | | Α-D-galactose | Generator | | (+)-Galactose | HMDB | | 5Abp | HMDB | | 8Abp | HMDB | | alpha-D-Galactopyranose | HMDB | | D-(+)-Galactose | HMDB | | D-Hexose | HMDB | | GAL | HMDB | | Galactose | HMDB | | Galactose (NF) | HMDB | | GLA | HMDB | | GLC | HMDB | | Hexose | HMDB | | SHU 508 a | MeSH, HMDB | | SH-TA-508 | MeSH, HMDB | | SHU 508 | MeSH, HMDB | | Levovist | MeSH, HMDB | | SHU-508 | MeSH, HMDB |
| Show more...
|---|
| Chemical Formula | C6H12O6 |
|---|
| Average Molecular Weight | 180.1559 |
|---|
| Monoisotopic Molecular Weight | 180.063388116 |
|---|
| IUPAC Name | (2S,3R,4S,5R,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol |
|---|
| Traditional Name | galactose |
|---|
| CAS Registry Number | 3646-73-9 |
|---|
| SMILES | OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O |
|---|
| InChI Identifier | InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6+/m1/s1 |
|---|
| InChI Key | WQZGKKKJIJFFOK-PHYPRBDBSA-N |
|---|
| Chemical Taxonomy |
|---|
| Description | Belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity. |
|---|
| Kingdom | Organic compounds |
|---|
| Super Class | Organic oxygen compounds |
|---|
| Class | Organooxygen compounds |
|---|
| Sub Class | Carbohydrates and carbohydrate conjugates |
|---|
| Direct Parent | Hexoses |
|---|
| Alternative Parents | |
|---|
| Substituents | - Hexose monosaccharide
- Oxane
- Secondary alcohol
- Hemiacetal
- Oxacycle
- Organoheterocyclic compound
- Polyol
- Hydrocarbon derivative
- Primary alcohol
- Alcohol
- Aliphatic heteromonocyclic compound
|
|---|
| Molecular Framework | Aliphatic heteromonocyclic compounds |
|---|
| External Descriptors | |
|---|
| Ontology |
|---|
| Physiological effect | Not Available |
|---|
| Disposition | Biological locationSourceEndogenousExogenousFoodAnimal originFruitVegetableHerb and spiceGourdPulseCereal and cereal productNutTeaBeverageAquatic originConfectioneryMilk and milk productOther milk productFermented milk productFermented milkUnfermented milk- Milk (Cow) (FooDB: FOOD00618)
- Cow milk, pasteurized, vitamin A + D added, 0% fat (FooDB: FOOD00889)
- Cow milk, pasteurized, vitamin A + D added, 1% fat (FooDB: FOOD00890)
- Cow milk, pasteurized, vitamin A + D added, 2% fat (FooDB: FOOD00891)
- Cow milk, pasteurized, vitamin D added, 3.25% fat (FooDB: FOOD00892)
Baby foodSoyUnclassified food or beverageDishCocoa and cocoa productCoffee and coffee productSnackEggBaking good |
|---|
| Process | |
|---|
| Role | |
|---|
| Physical Properties |
|---|
| State | Solid |
|---|
| Experimental Molecular Properties | | Property | Value | Reference |
|---|
| Melting Point | 170 °C | Not Available | | Boiling Point | Not Available | Not Available | | Water Solubility | 683 mg/mL | Not Available | | LogP | Not Available | Not Available |
|
|---|
| Experimental Chromatographic Properties | Experimental Collision Cross Sections| Adduct Type | Data Source | CCS Value (Å2) | Reference |
|---|
| [M-H]- | Astarita_neg | 130.0 | 30932474 |
|
|---|
| Predicted Molecular Properties | | Show more...
|---|
| Predicted Chromatographic Properties | Predicted Collision Cross SectionsPredicted Kovats Retention IndicesUnderivatizedDerivatized| Derivative Name / Structure | SMILES | Kovats RI Value | Column Type | Reference |
|---|
| D-Galactose,1TMS,isomer #1 | C[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O | 1738.4 | Semi standard non polar | 33892256 | | D-Galactose,1TMS,isomer #2 | C[Si](C)(C)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O | 1673.8 | Semi standard non polar | 33892256 | | D-Galactose,1TMS,isomer #3 | C[Si](C)(C)O[C@H]1[C@@H](O)O[C@H](CO)[C@H](O)[C@@H]1O | 1683.6 | Semi standard non polar | 33892256 | | D-Galactose,1TMS,isomer #4 | C[Si](C)(C)O[C@H]1[C@@H](O)[C@@H](CO)O[C@H](O)[C@@H]1O | 1688.3 | Semi standard non polar | 33892256 | | D-Galactose,1TMS,isomer #5 | C[Si](C)(C)O[C@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O | 1678.0 | Semi standard non polar | 33892256 | | D-Galactose,2TMS,isomer #1 | C[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C)[C@H](O)[C@@H](O)[C@H]1O | 1722.4 | Semi standard non polar | 33892256 | | D-Galactose,2TMS,isomer #10 | C[Si](C)(C)O[C@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O[Si](C)(C)C | 1681.6 | Semi standard non polar | 33892256 | | D-Galactose,2TMS,isomer #2 | C[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O[Si](C)(C)C)[C@@H](O)[C@H]1O | 1737.0 | Semi standard non polar | 33892256 | | D-Galactose,2TMS,isomer #3 | C[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O[Si](C)(C)C)[C@H]1O | 1742.6 | Semi standard non polar | 33892256 | | D-Galactose,2TMS,isomer #4 | C[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O[Si](C)(C)C | 1712.2 | Semi standard non polar | 33892256 | | D-Galactose,2TMS,isomer #5 | C[Si](C)(C)O[C@H]1O[C@H](CO)[C@H](O[Si](C)(C)C)[C@H](O)[C@H]1O | 1701.4 | Semi standard non polar | 33892256 | | D-Galactose,2TMS,isomer #6 | C[Si](C)(C)O[C@H]1[C@@H](O)[C@@H](CO)O[C@H](O[Si](C)(C)C)[C@@H]1O | 1703.5 | Semi standard non polar | 33892256 | | D-Galactose,2TMS,isomer #7 | C[Si](C)(C)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O[Si](C)(C)C | 1679.6 | Semi standard non polar | 33892256 | | D-Galactose,2TMS,isomer #8 | C[Si](C)(C)O[C@H]1[C@@H](O)O[C@H](CO)[C@H](O[Si](C)(C)C)[C@@H]1O | 1697.1 | Semi standard non polar | 33892256 | | D-Galactose,2TMS,isomer #9 | C[Si](C)(C)O[C@H]1[C@@H](O)[C@@H](CO)O[C@H](O)[C@@H]1O[Si](C)(C)C | 1692.2 | Semi standard non polar | 33892256 | | D-Galactose,3TMS,isomer #1 | C[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H](O)[C@H]1O | 1703.6 | Semi standard non polar | 33892256 | | D-Galactose,3TMS,isomer #10 | C[Si](C)(C)O[C@@H]1[C@H](O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@@H](O)O[C@@H]1CO | 1736.7 | Semi standard non polar | 33892256 | | D-Galactose,3TMS,isomer #2 | C[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C)[C@H](O)[C@@H](O[Si](C)(C)C)[C@H]1O | 1753.4 | Semi standard non polar | 33892256 | | D-Galactose,3TMS,isomer #3 | C[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C)[C@H](O)[C@@H](O)[C@H]1O[Si](C)(C)C | 1717.5 | Semi standard non polar | 33892256 | | D-Galactose,3TMS,isomer #4 | C[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H]1O | 1748.2 | Semi standard non polar | 33892256 | | D-Galactose,3TMS,isomer #5 | C[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O[Si](C)(C)C)[C@@H](O)[C@H]1O[Si](C)(C)C | 1766.0 | Semi standard non polar | 33892256 | | D-Galactose,3TMS,isomer #6 | C[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C | 1701.0 | Semi standard non polar | 33892256 | | D-Galactose,3TMS,isomer #7 | C[Si](C)(C)O[C@H]1[C@@H](CO)O[C@H](O[Si](C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C | 1739.0 | Semi standard non polar | 33892256 | | D-Galactose,3TMS,isomer #8 | C[Si](C)(C)O[C@H]1O[C@H](CO)[C@H](O[Si](C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C | 1733.4 | Semi standard non polar | 33892256 | | D-Galactose,3TMS,isomer #9 | C[Si](C)(C)O[C@H]1[C@@H](O)[C@@H](CO)O[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C | 1725.4 | Semi standard non polar | 33892256 | | D-Galactose,4TMS,isomer #1 | C[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H]1O | 1815.5 | Semi standard non polar | 33892256 | | D-Galactose,4TMS,isomer #2 | C[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H](O)[C@H]1O[Si](C)(C)C | 1815.2 | Semi standard non polar | 33892256 | | D-Galactose,4TMS,isomer #3 | C[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C)[C@H](O)[C@@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C | 1820.5 | Semi standard non polar | 33892256 | | D-Galactose,4TMS,isomer #4 | C[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C | 1819.4 | Semi standard non polar | 33892256 | | D-Galactose,4TMS,isomer #5 | C[Si](C)(C)O[C@@H]1[C@H](O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)O[C@@H]1CO | 1800.9 | Semi standard non polar | 33892256 | | D-Galactose,5TMS,isomer #1 | C[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C | 1877.4 | Semi standard non polar | 33892256 | | D-Galactose,1TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O | 2002.6 | Semi standard non polar | 33892256 | | D-Galactose,1TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O | 1940.1 | Semi standard non polar | 33892256 | | D-Galactose,1TBDMS,isomer #3 | CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)O[C@H](CO)[C@H](O)[C@@H]1O | 1940.5 | Semi standard non polar | 33892256 | | D-Galactose,1TBDMS,isomer #4 | CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)[C@@H](CO)O[C@H](O)[C@@H]1O | 1947.1 | Semi standard non polar | 33892256 | | D-Galactose,1TBDMS,isomer #5 | CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O | 1943.8 | Semi standard non polar | 33892256 | | D-Galactose,2TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H](O)[C@H]1O | 2208.7 | Semi standard non polar | 33892256 | | D-Galactose,2TBDMS,isomer #10 | CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C | 2181.6 | Semi standard non polar | 33892256 | | D-Galactose,2TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H]1O | 2210.9 | Semi standard non polar | 33892256 | | D-Galactose,2TBDMS,isomer #3 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1O | 2219.8 | Semi standard non polar | 33892256 | | D-Galactose,2TBDMS,isomer #4 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O[Si](C)(C)C(C)(C)C | 2197.5 | Semi standard non polar | 33892256 | | D-Galactose,2TBDMS,isomer #5 | CC(C)(C)[Si](C)(C)O[C@H]1O[C@H](CO)[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O | 2193.9 | Semi standard non polar | 33892256 | | D-Galactose,2TBDMS,isomer #6 | CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)[C@@H](CO)O[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O | 2195.0 | Semi standard non polar | 33892256 | | D-Galactose,2TBDMS,isomer #7 | CC(C)(C)[Si](C)(C)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C | 2180.7 | Semi standard non polar | 33892256 | | D-Galactose,2TBDMS,isomer #8 | CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)O[C@H](CO)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O | 2190.8 | Semi standard non polar | 33892256 | | D-Galactose,2TBDMS,isomer #9 | CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)[C@@H](CO)O[C@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C | 2192.8 | Semi standard non polar | 33892256 | | D-Galactose,3TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H]1O | 2441.4 | Semi standard non polar | 33892256 | | D-Galactose,3TBDMS,isomer #10 | CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](O)O[C@@H]1CO | 2455.2 | Semi standard non polar | 33892256 | | D-Galactose,3TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1O | 2449.6 | Semi standard non polar | 33892256 | | D-Galactose,3TBDMS,isomer #3 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H](O)[C@H]1O[Si](C)(C)C(C)(C)C | 2445.1 | Semi standard non polar | 33892256 | | D-Galactose,3TBDMS,isomer #4 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1O | 2466.7 | Semi standard non polar | 33892256 | | D-Galactose,3TBDMS,isomer #5 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H]1O[Si](C)(C)C(C)(C)C | 2468.7 | Semi standard non polar | 33892256 | | D-Galactose,3TBDMS,isomer #6 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C | 2439.7 | Semi standard non polar | 33892256 | | D-Galactose,3TBDMS,isomer #7 | CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](CO)O[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C | 2451.2 | Semi standard non polar | 33892256 | | D-Galactose,3TBDMS,isomer #8 | CC(C)(C)[Si](C)(C)O[C@H]1O[C@H](CO)[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C | 2451.3 | Semi standard non polar | 33892256 | | D-Galactose,3TBDMS,isomer #9 | CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)[C@@H](CO)O[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C | 2454.9 | Semi standard non polar | 33892256 | | D-Galactose,4TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1O | 2671.4 | Semi standard non polar | 33892256 | | D-Galactose,4TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H]1O[Si](C)(C)C(C)(C)C | 2668.4 | Semi standard non polar | 33892256 | | D-Galactose,4TBDMS,isomer #3 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C | 2664.4 | Semi standard non polar | 33892256 | | D-Galactose,4TBDMS,isomer #4 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C | 2681.0 | Semi standard non polar | 33892256 | | D-Galactose,4TBDMS,isomer #5 | CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)O[C@@H]1CO | 2669.4 | Semi standard non polar | 33892256 | | D-Galactose,5TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)OC[C@H]1O[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C | 2890.3 | Semi standard non polar | 33892256 |
| Show more...
|---|
| Spectra |
|---|
| GC-MS Spectra| Spectrum Type | Description | Splash Key | Deposition Date | Source | View |
|---|
| Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-066s-0941000000-8f1b68655e0a5ed179e3 | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-0ldj-0941000000-84c771fab416aa0a40d8 | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-0ktb-0931000000-6f37a774d1ab64585c8d | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-066s-0931000000-9945093085ef7b0de618 | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-0ldj-0931000000-1ed532d5d2897be775df | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-00di-9731000000-af5bd67ad0bbb2997839 | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-00di-9621000000-9dad5bd1760a891ace2a | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-0fr2-0920000000-d0bbaf502997c43971ba | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-0fr2-1920000000-f47f0b66263744db15ba | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-066s-0941000000-8f1b68655e0a5ed179e3 | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-0ldj-0941000000-84c771fab416aa0a40d8 | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-0ktb-0931000000-6f37a774d1ab64585c8d | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-066s-0931000000-9945093085ef7b0de618 | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-0ldj-0931000000-1ed532d5d2897be775df | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-00di-9731000000-af5bd67ad0bbb2997839 | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-00di-9621000000-9dad5bd1760a891ace2a | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-0fr2-0920000000-d0bbaf502997c43971ba | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Experimental GC-MS | GC-MS Spectrum - D-Galactose GC-EI-TOF (Non-derivatized) | splash10-0fr2-1920000000-f47f0b66263744db15ba | 2018-05-25 | HMDB team, MONA, MassBank | View Spectrum | | Predicted GC-MS | Predicted GC-MS Spectrum - D-Galactose GC-MS (Non-derivatized) - 70eV, Positive | splash10-0np0-9700000000-e8d638dc817e46b97d7b | 2016-09-22 | Wishart Lab | View Spectrum | | Predicted GC-MS | Predicted GC-MS Spectrum - D-Galactose GC-MS (5 TMS) - 70eV, Positive | splash10-004i-6122690000-eaf6f7adf34ccd0c667b | 2017-10-06 | Wishart Lab | View Spectrum | | Predicted GC-MS | Predicted GC-MS Spectrum - D-Galactose GC-MS (Non-derivatized) - 70eV, Positive | Not Available | 2021-10-12 | Wishart Lab | View Spectrum | | Predicted GC-MS | Predicted GC-MS Spectrum - D-Galactose GC-MS (Non-derivatized) - 70eV, Positive | Not Available | 2021-10-12 | Wishart Lab | View Spectrum | | Predicted GC-MS | Predicted GC-MS Spectrum - D-Galactose GC-MS (TMS_1_1) - 70eV, Positive | Not Available | 2021-11-05 | Wishart Lab | View Spectrum | | Predicted GC-MS | Predicted GC-MS Spectrum - D-Galactose GC-MS (TMS_1_2) - 70eV, Positive | Not Available | 2021-11-05 | Wishart Lab | View Spectrum | | Predicted GC-MS | Predicted GC-MS Spectrum - D-Galactose GC-MS (TMS_1_3) - 70eV, Positive | Not Available | 2021-11-05 | Wishart Lab | View Spectrum |
MS/MS Spectra| Spectrum Type | Description | Splash Key | Deposition Date | Source | View |
|---|
| Experimental LC-MS/MS | LC-MS/MS Spectrum - D-Galactose Quattro_QQQ 10V, Positive-QTOF (Annotated) | splash10-0f6t-0900000000-70d3989fddd34b894c77 | 2012-07-24 | HMDB team, MONA | View Spectrum | | Experimental LC-MS/MS | LC-MS/MS Spectrum - D-Galactose Quattro_QQQ 25V, Positive-QTOF (Annotated) | splash10-00ri-9700000000-d454170b4e3ed18ed2d9 | 2012-07-24 | HMDB team, MONA | View Spectrum | | Experimental LC-MS/MS | LC-MS/MS Spectrum - D-Galactose Quattro_QQQ 40V, Positive-QTOF (Annotated) | splash10-007a-9300000000-81f5f12f84924a34e2c0 | 2012-07-24 | HMDB team, MONA | View Spectrum | | Experimental LC-MS/MS | LC-MS/MS Spectrum - D-Galactose LC-ESI-QTOF 10V, negative-QTOF | splash10-059i-9100000000-33aacf4c62b17cfa394e | 2020-07-21 | HMDB team, MONA | View Spectrum | | Experimental LC-MS/MS | LC-MS/MS Spectrum - D-Galactose LC-ESI-QTOF 20V, negative-QTOF | splash10-0a4i-9000000000-79ea696263aaad168701 | 2020-07-21 | HMDB team, MONA | View Spectrum | | Experimental LC-MS/MS | LC-MS/MS Spectrum - D-Galactose LC-ESI-QTOF 40V, negative-QTOF | splash10-0a4i-9000000000-480461c1cdd9d138dce2 | 2020-07-21 | HMDB team, MONA | View Spectrum | | Experimental LC-MS/MS | LC-MS/MS Spectrum - D-Galactose 10V, Negative-QTOF | splash10-059i-9100000000-33aacf4c62b17cfa394e | 2021-09-20 | HMDB team, MONA | View Spectrum | | Experimental LC-MS/MS | LC-MS/MS Spectrum - D-Galactose 20V, Negative-QTOF | splash10-0a4i-9000000000-79ea696263aaad168701 | 2021-09-20 | HMDB team, MONA | View Spectrum | | Experimental LC-MS/MS | LC-MS/MS Spectrum - D-Galactose 40V, Negative-QTOF | splash10-0a4i-9000000000-480461c1cdd9d138dce2 | 2021-09-20 | HMDB team, MONA | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 10V, Positive-QTOF | splash10-01q9-0900000000-b0bc47623e7b2ca31c02 | 2016-09-12 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 20V, Positive-QTOF | splash10-03ea-3900000000-648e1637af29cf2a3518 | 2016-09-12 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 40V, Positive-QTOF | splash10-0007-9200000000-9e6f46a1cbf52d6e347a | 2016-09-12 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 10V, Negative-QTOF | splash10-004i-2900000000-a4ec4f0b1e29e360a952 | 2016-09-12 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 20V, Negative-QTOF | splash10-01t9-6900000000-7b3ea9c64ecc8d4ac867 | 2016-09-12 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 40V, Negative-QTOF | splash10-052f-9100000000-ec2bf4918640a0a36398 | 2016-09-12 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 10V, Negative-QTOF | splash10-004i-2900000000-2448926b508622464fe7 | 2021-09-23 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 20V, Negative-QTOF | splash10-056r-8900000000-4c073cb93b78120113e6 | 2021-09-23 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 40V, Negative-QTOF | splash10-0a4l-9000000000-ece70093ab5d3c331ac4 | 2021-09-23 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 10V, Positive-QTOF | splash10-01qa-0900000000-04ceb34d441ff6a75763 | 2021-09-25 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 20V, Positive-QTOF | splash10-03dl-9400000000-a8f1ceab155611f949c1 | 2021-09-25 | Wishart Lab | View Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - D-Galactose 40V, Positive-QTOF | splash10-01ow-9000000000-358f68fc2b7a72c27546 | 2021-09-25 | Wishart Lab | View Spectrum |
NMR Spectra| Spectrum Type | Description | Deposition Date | Source | View |
|---|
| Predicted 1D NMR | 13C NMR Spectrum (1D, 100 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 1H NMR Spectrum (1D, 100 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 13C NMR Spectrum (1D, 1000 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 1H NMR Spectrum (1D, 1000 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 13C NMR Spectrum (1D, 200 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 1H NMR Spectrum (1D, 200 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 13C NMR Spectrum (1D, 300 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 1H NMR Spectrum (1D, 300 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 13C NMR Spectrum (1D, 400 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 1H NMR Spectrum (1D, 400 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 13C NMR Spectrum (1D, 500 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 1H NMR Spectrum (1D, 500 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 13C NMR Spectrum (1D, 600 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 1H NMR Spectrum (1D, 600 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 13C NMR Spectrum (1D, 700 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 1H NMR Spectrum (1D, 700 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 13C NMR Spectrum (1D, 800 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 1H NMR Spectrum (1D, 800 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 13C NMR Spectrum (1D, 900 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Predicted 1D NMR | 1H NMR Spectrum (1D, 900 MHz, D2O, predicted) | 2021-09-29 | Wishart Lab | View Spectrum | | Experimental 1D NMR | 13C NMR Spectrum (1D, 400 MHz, H2O, experimental) | 2021-10-10 | Wishart Lab | View Spectrum | | Experimental 2D NMR | [1H, 13C]-HSQC NMR Spectrum (2D, 400 MHz, H2O, experimental) | 2012-12-04 | Wishart Lab | View Spectrum |
IR Spectra| Spectrum Type | Description | Deposition Date | Source | View |
|---|
| Predicted IR Spectrum | IR Ion Spectrum (Predicted IRIS Spectrum, Adduct: [M-H]-) | 2023-02-03 | FELIX lab | View Spectrum | | Predicted IR Spectrum | IR Ion Spectrum (Predicted IRIS Spectrum, Adduct: [M+H]+) | 2023-02-03 | FELIX lab | View Spectrum | | Predicted IR Spectrum | IR Ion Spectrum (Predicted IRIS Spectrum, Adduct: [M+Na]+) | 2023-02-03 | FELIX lab | View Spectrum |
| Show more...
|---|
| Biological Properties |
|---|
| Cellular Locations | |
|---|
| Biospecimen Locations | - Blood
- Breast Milk
- Cellular Cytoplasm
- Cerebrospinal Fluid (CSF)
- Feces
- Saliva
- Urine
|
|---|
| Tissue Locations | |
|---|
| Pathways | |
|---|
| Normal Concentrations |
|---|
| |
| Blood | Detected and Quantified | <440 uM | Newborn (0-30 days old) | Not Available | Normal | | details | | Blood | Detected and Quantified | <110 uM | Infant (0-1 year old) | Not Available | Normal | | details | | Blood | Detected and Quantified | 210.0 +/- 92.0 uM | Children (1-13 years old) | Both | Normal | | details | | Blood | Detected and Quantified | 88.3 +/- 34.7 uM | Adult (>18 years old) | Both | Normal | | details | | Blood | Detected and Quantified | 39.0 +/- 12.0 uM | Adult (>18 years old) | Male | Normal | | details | | Blood | Detected and Quantified | 17 (0-39) uM | Children (1 - 13 years old) | Not Specified | Normal | | details | | Blood | Detected and Quantified | 1.0 (0.0-5.0) uM | Adolescent (13-18 years old) | Both | Normal | | details | | Breast Milk | Detected and Quantified | 92.3 +/- 49.1 uM | Adult (>18 years old) | Female | Normal | | details | | Cellular Cytoplasm | Detected and Quantified | 4.6 (0.0-9.2) uM | Children (1-13 years old) | Both | Normal | | details | | Cerebrospinal Fluid (CSF) | Detected and Quantified | 166.0 +/- 99.0 uM | Adult (>18 years old) | Both | Normal | | details | | Feces | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Both | Normal | | details | | Feces | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Not Specified | Normal | | details | | Feces | Detected and Quantified | 746.576 +/- 394.103 nmol/g wet feces | Not Specified | Not Specified | Normal | | details | | Feces | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Both | Normal | | details | | Feces | Detected but not Quantified | Not Quantified | Not Specified | Not Specified | Normal | | details | | Feces | Detected but not Quantified | Not Quantified | Infant (0-1 year old) | Both | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Male | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Male | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Male | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Male | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Male | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Male | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Male | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Male | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Male | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Male | Normal | | details | | Saliva | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Not Specified | Normal | | details | | Saliva | Detected and Quantified | 83.46 +/- 31.16 uM | Adult (>18 years old) | Both | Normal | | details | | Urine | Detected and Quantified | 3.3 (1.3-8.5) umol/mmol creatinine | Adult (>18 years old) | Both | Normal | | details | | Urine | Detected and Quantified | 262.58 +/- 881.72 umol/mmol creatinine | Infant (0-1 year old) | Both | Normal | | details | | Urine | Detected and Quantified | 11.9 (5.4-25.2) umol/mmol creatinine | Adult (>18 years old) | Both | Normal | | details | | Urine | Detected and Quantified | 5.0 (0.0-19.0) umol/mmol creatinine | Newborn (0-30 days old) | Both | Normal | | details | | Urine | Detected and Quantified | 3.8 (0.0-11.0) umol/mmol creatinine | Adolescent (13-18 years old) | Both | Normal | | details | | Urine | Detected and Quantified | 0-500 umol/mmol creatinine | Newborn (0-30 days old) | Both | Normal | | details | | Urine | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Both | Normal | | details | | Urine | Detected and Quantified | 15.0 (0.0-33.0) umol/mmol creatinine | Infant (0-1 year old) | Both | Normal | | details | | Urine | Detected and Quantified | 4.4 (0.0-31.0) umol/mmol creatinine | Adult (>18 years old) | Both | Normal | | details | | Urine | Detected and Quantified | 10.034 +/- 12.935 umol/mmol creatinine | Children (1 - 13 years old) | Not Specified | Normal | | details | | Urine | Detected and Quantified | 85-140 umol/mmol creatinine | Newborn (0-30 days old) | Both | Normal | | details |
| Show more...
|---|
| Abnormal Concentrations |
|---|
| |
| Blood | Detected and Quantified | 2.720 (0.580-3.980) uM | Infant (0-1 year old) | Both | Galactosemia type 1 | | details | | Blood | Detected and Quantified | 0.52 (0.12-1.25) uM | Infant (0-1 year old) | Both | Hypergalactosemia with porto-hepatic venous shunts and haemangiomas | | details | | Blood | Detected and Quantified | 2.72 (0.58-3.98) uM | Infant (0-1 year old) | Both | Galactose-1-phosphate uridyltransferase deficiency (galactosemia) | | details | | Blood | Detected and Quantified | 440-1110 uM | Newborn (0-30 days old) | Not Available | Patent Ductus Venosus | | details | | Blood | Detected and Quantified | <110 uM | Infant (0-1 year old) | Not Available | Patent Ductus Venosus | | details | | Blood | Detected and Quantified | 330-440 uM | Children (1-13 years old) | Not Available | Patent Ductus Venosus | | details | | Cellular Cytoplasm | Detected and Quantified | 1496.5 (921.0 - 2070) uM | Children (1-13 years old) | Both | Galactosemia | | details | | Feces | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Both | Colorectal Cancer | | details | | Feces | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Both | Colorectal cancer | | details | | Feces | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Both | Colorectal cancer | | details | | Urine | Detected but not Quantified | Not Quantified | Adult (>18 years old) | Both | Bladder cancer | | details | | Urine | Detected and Quantified | 12.219 +/- 17.901 umol/mmol creatinine | Children (1 - 13 years old) | Not Specified | Eosinophilic esophagitis | | details |
| Show more...
|---|
| Associated Disorders and Diseases |
|---|
| Disease References | | Galactose-1-phosphate uridyltransferase deficiency |
|---|
- Ning C, Segal S: Plasma galactose and galactitol concentration in patients with galactose-1-phosphate uridyltransferase deficiency galactosemia: determination by gas chromatography/mass spectrometry. Metabolism. 2000 Nov;49(11):1460-6. [PubMed:11092512 ]
| | Galactosemia type 1 |
|---|
- Ning C, Segal S: Plasma galactose and galactitol concentration in patients with galactose-1-phosphate uridyltransferase deficiency galactosemia: determination by gas chromatography/mass spectrometry. Metabolism. 2000 Nov;49(11):1460-6. [PubMed:11092512 ]
| | Patent Ductus Venosus |
|---|
- Sakura N, Mizoguchi N, Eguchi T, Ono H, Mawatari H, Naitou K, Ito K: Elevated plasma bile acids in hypergalactosaemic neonates: a diagnostic clue to portosystemic shunts. Eur J Pediatr. 1997 Sep;156(9):716-8. [PubMed:9296537 ]
| | Galactosemia |
|---|
- Chen J, Yager C, Reynolds R, Palmieri M, Segal S: Erythrocyte galactose 1-phosphate quantified by isotope-dilution gas chromatography-mass spectrometry. Clin Chem. 2002;48(4):604-12. [PubMed:11901058 ]
| | Colorectal cancer |
|---|
- Brown DG, Rao S, Weir TL, O'Malia J, Bazan M, Brown RJ, Ryan EP: Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool. Cancer Metab. 2016 Jun 6;4:11. doi: 10.1186/s40170-016-0151-y. eCollection 2016. [PubMed:27275383 ]
- Sinha R, Ahn J, Sampson JN, Shi J, Yu G, Xiong X, Hayes RB, Goedert JJ: Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations. PLoS One. 2016 Mar 25;11(3):e0152126. doi: 10.1371/journal.pone.0152126. eCollection 2016. [PubMed:27015276 ]
- Goedert JJ, Sampson JN, Moore SC, Xiao Q, Xiong X, Hayes RB, Ahn J, Shi J, Sinha R: Fecal metabolomics: assay performance and association with colorectal cancer. Carcinogenesis. 2014 Sep;35(9):2089-96. doi: 10.1093/carcin/bgu131. Epub 2014 Jul 18. [PubMed:25037050 ]
| | Eosinophilic esophagitis |
|---|
- Slae, M., Huynh, H., Wishart, D.S. (2014). Analysis of 30 normal pediatric urine samples via NMR spectroscopy (unpublished work). NA.
|
|
|---|
| Associated OMIM IDs | - 230400 (Galactose-1-phosphate uridyltransferase deficiency)
- 230400 (Galactosemia type 1)
- 601466 (Patent Ductus Venosus)
- 114500 (Colorectal cancer)
- 610247 (Eosinophilic esophagitis)
|
|---|
| External Links |
|---|
| DrugBank ID | Not Available |
|---|
| Phenol Explorer Compound ID | Not Available |
|---|
| FooDB ID | FDB021787 |
|---|
| KNApSAcK ID | C00001119 |
|---|
| Chemspider ID | Not Available |
|---|
| KEGG Compound ID | C00984 |
|---|
| BioCyc ID | ALPHA-D-GALACTOSE |
|---|
| BiGG ID | Not Available |
|---|
| Wikipedia Link | Galactose |
|---|
| METLIN ID | Not Available |
|---|
| PubChem Compound | 439357 |
|---|
| PDB ID | Not Available |
|---|
| ChEBI ID | 28061 |
|---|
| Food Biomarker Ontology | Not Available |
|---|
| VMH ID | GAL |
|---|
| MarkerDB ID | Not Available |
|---|
| Good Scents ID | Not Available |
|---|
| References |
|---|
| Synthesis Reference | Avigad, Gad. Synthesis of D-galactose-6-t and D-galactosides-6-t. Carbohydrate Research (1967), 3(4), 430-4. |
|---|
| Material Safety Data Sheet (MSDS) | Not Available |
|---|
| General References | - Tyfield L, Reichardt J, Fridovich-Keil J, Croke DT, Elsas LJ 2nd, Strobl W, Kozak L, Coskun T, Novelli G, Okano Y, Zekanowski C, Shin Y, Boleda MD: Classical galactosemia and mutations at the galactose-1-phosphate uridyl transferase (GALT) gene. Hum Mutat. 1999;13(6):417-30. [PubMed:10408771 ]
- Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. doi: 10.1038/nature07762. [PubMed:19212411 ]
- Shoemaker JD, Elliott WH: Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease. J Chromatogr. 1991 Jan 2;562(1-2):125-38. [PubMed:2026685 ]
- Silwood CJ, Lynch E, Claxson AW, Grootveld MC: 1H and (13)C NMR spectroscopic analysis of human saliva. J Dent Res. 2002 Jun;81(6):422-7. [PubMed:12097436 ]
- Ning C, Segal S: Plasma galactose and galactitol concentration in patients with galactose-1-phosphate uridyltransferase deficiency galactosemia: determination by gas chromatography/mass spectrometry. Metabolism. 2000 Nov;49(11):1460-6. [PubMed:11092512 ]
- Ning C, Reynolds R, Chen J, Yager C, Berry GT, McNamara PD, Leslie N, Segal S: Galactose metabolism by the mouse with galactose-1-phosphate uridyltransferase deficiency. Pediatr Res. 2000 Aug;48(2):211-7. [PubMed:10926297 ]
- Rapoport EM, Nekrasov MV, Khaidukov SV, Svirshchevskaya EV, Zhigis LS, Kozlov LV, Batalova TN, Zubov VP, Bovin NV: Cellular localization of the galactose-binding lectin from human serum. Biochemistry (Mosc). 2000 Nov;65(11):1316-20. [PubMed:11112850 ]
- Xu J, Ma M, Purcell WM: Optimizing the enzymatic determination of galactose in the culture medium of rat liver and HepG2 cell spheroids. Anal Biochem. 2002 Dec 15;311(2):179-81. [PubMed:12470678 ]
- Seiler CA, Renner EL, Czerniak A, Didonna D, Buchler MW, Reichen J: Early acute cellular rejection: no effect on late hepatic allograft function in man. Transpl Int. 1999;12(3):195-201. [PubMed:10429957 ]
- Schadewaldt P, Hammen HW, Loganathan K, Bodner-Leidecker A, Wendel U: Analysis of concentration and (13)C enrichment of D-galactose in human plasma. Clin Chem. 2000 May;46(5):612-9. [PubMed:10794741 ]
- Fenn PT, Ning C, Segal S, Blair IA: Determination of [(13)C]galactose enrichment in human plasma by gas chromatography/positive chemical ionization tandem mass spectrometry. J Mass Spectrom. 2000 Feb;35(2):218-23. [PubMed:10679984 ]
- van den Nieuwenhof IM, Renardel de Lavalette C, Diaz N, van Die I, van den Berg TK: Differential galactosylation of neuronal and haematopoietic signal regulatory protein-alpha determines its cellular binding-specificity. J Cell Sci. 2001 Apr;114(Pt 7):1321-9. [PubMed:11256998 ]
- Hernandez DE, Cohen A, Fisher D, Correnti M, Harner R: Antibody levels against galactosyl (alpha1 --> 3) galactose epitopes in cervical mucus from patients with human papillomavirus infection. Gynecol Oncol. 2002 Mar;84(3):374-7. [PubMed:11855872 ]
- Ono H, Mawatari H, Mizoguchi N, Eguchi T, Sakura N, Hamakawa M: Transient galactosemia detected by neonatal mass screening. Pediatr Int. 1999 Jun;41(3):281-4. [PubMed:10365579 ]
- Tamamori A, Fujimoto A, Okano Y, Kobayashi K, Saheki T, Tagami Y, Takei H, Shigematsu Y, Hata I, Ozaki H, Tokuhara D, Nishimura Y, Yorifuji T, Igarashi N, Ohura T, Shimizu T, Inui K, Sakai N, Abukawa D, Miyakawa T, Matsumori M, Ban K, Kaneko H, Yamano T: Effects of citrin deficiency in the perinatal period: feasibility of newborn mass screening for citrin deficiency. Pediatr Res. 2004 Oct;56(4):608-14. Epub 2004 Aug 4. [PubMed:15295082 ]
- Wang ZJ, Berry GT, Dreha SF, Zhao H, Segal S, Zimmerman RA: Proton magnetic resonance spectroscopy of brain metabolites in galactosemia. Ann Neurol. 2001 Aug;50(2):266-9. [PubMed:11506413 ]
- Niebroj-Dobosz I, Janik P, Jamrozik Z, Kwiecinski H: Immunochemical quantification of glycoconjugates in serum and cerebrospinal fluid of amyotrophic lateral sclerosis patients. Eur J Neurol. 1999 May;6(3):335-40. [PubMed:10210915 ]
- Schmidt LE, Ott P, Tygstrup N: Galactose elimination capacity as a prognostic marker in patients with severe acetaminophen-induced hepatotoxicity: 10 years' experience. Clin Gastroenterol Hepatol. 2004 May;2(5):418-24. [PubMed:15118981 ]
- Vironen J, Kellokumpu S, Andersson LC, Kellokumpu I: Comparison of a peanut agglutinin test and an immunochemical faecal occult blood test in detecting colorectal neoplasia in symptomatic patients. Scand J Clin Lab Invest. 2004 Apr;64(2):140-5. [PubMed:15115252 ]
- Yago H, Kohgo Y, Kato J, Watanabe N, Sakamaki S, Niitsu Y: Detection and quantification of soluble asialoglycoprotein receptor in human serum. Hepatology. 1995 Feb;21(2):383-8. [PubMed:7843709 ]
- Chen J, Yager C, Reynolds R, Palmieri M, Segal S: Erythrocyte galactose 1-phosphate quantified by isotope-dilution gas chromatography-mass spectrometry. Clin Chem. 2002;48(4):604-12. [PubMed:11901058 ]
- Mizoguchi N, Ono H, Eguchi T, Sakura N: Galactose metabolites in blood from neonates with and without hypergalactosaemia detected by mass screening. Eur J Pediatr. 2000 Nov;159(11):851-3. [PubMed:11079200 ]
- Cavalli C, Teng C, Battaglia FC, Bevilacqua G: Free sugar and sugar alcohol concentrations in human breast milk. J Pediatr Gastroenterol Nutr. 2006 Feb;42(2):215-21. [PubMed:16456418 ]
- Shamsuddin AM, Tyner GT, Yang GY: Common expression of the tumor marker D-galactose-beta-[1-->3]-N-acetyl-D-galactosamine by different adenocarcinomas: evidence of field effect phenomenon. Cancer Res. 1995 Jan 1;55(1):149-52. [PubMed:7805025 ]
- Wan CC, Muldrey JE, Li SC, Li YT: beta-Mannosidase from the mushroom Polyporus sulfureus. J Biol Chem. 1976 Jul 25;251(14):4384-8. [PubMed:6478 ]
- Redaelli CA, Dufour JF, Wagner M, Schilling M, Husler J, Krahenbuhl L, Buchler MW, Reichen J: Preoperative galactose elimination capacity predicts complications and survival after hepatic resection. Ann Surg. 2002 Jan;235(1):77-85. [PubMed:11753045 ]
- Rudzeviciene O, Narkeviciute I, Eidukevicius R: Lactose malabsorption in young Lithuanian children with atopic dermatitis. Acta Paediatr. 2004 Apr;93(4):482-6. [PubMed:15188975 ]
- Lai K, Klapa MI: Alternative pathways of galactose assimilation: could inverse metabolic engineering provide an alternative to galactosemic patients? Metab Eng. 2004 Jul;6(3):239-44. [PubMed:15256214 ]
- Liu G, Hale GE, Hughes CL: Galactose metabolism and ovarian toxicity. Reprod Toxicol. 2000 Sep-Oct;14(5):377-84. [PubMed:11020650 ]
| Show more...
|---|
