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Symbol report for MAP2K1

HGNC data for MAP2K1

Approved symbol
MAP2K1
Approved name

mitogen-activated protein kinase kinase 1

Locus type
gene with protein product
HGNC ID
HGNC:6840
Symbol status
Approved
Previous symbols
PRKMK1
Alias symbols
MEK1
MAPKK1
MKK1
Alias names
MAPK/ERK kinase 1
MAP kinase kinase 1
dual specificity mitogen-activated protein kinase kinase 1
Chromosomal location
15q22.31
Gene groups
Curator notes

MEK1 is a popular alias for this gene - it should not be confused with the unrelated meiotic kinase gene MEK1 in Saccharomyces cerevisiae.
Gene resources for MAP2K1
Ensembl
ENSG00000169032 Curated
Ensembl region in detailEnsembl gene sequence
NCBI Gene
5604 Curated
UCSC
uc010bhq.4
Alliance of Genome Resources
HGNC:6840
Nucleotide resources for MAP2K1
MANE Select
NM_002755.4
ENST00000307102.10
INSDC
L11284 Curated
ENAGenBankDDBJ
RefSeq
NM_001411065
NCBI sequence viewer
Protein resources for MAP2K1
UniProt/Swiss-Prot
Q02750
InterProPDBeReactome
AlphaFold
AF-Q02750-F1
Enzyme Commission
2.7.12.2 Curated
ExpasyBRENDAKEGGIntEnzIUBMB Enzyme Nomenclature
Orthologs from selected species for MAP2K1
Bos taurus
MAP2K1 VGNC:31183 VGNC
Canis familiaris
MAP2K1 VGNC:42960 VGNC
Equus caballus
MAP2K1 VGNC:19926 VGNC
Felis catus
MAP2K1 VGNC:80918 VGNC
Macaca mulatta
MAP2K1 VGNC:81452 VGNC
Mus musculus
Map2k1 MGI:1346866 Curated
Pan troglodytes
MAP2K1 VGNC:7531 VGNC
Rattus norvegicus
Map2k1 RGD:70495
Sus scrofa
MAP2K1 VGNC:103121 VGNC
Specialist resources for MAP2K1
IUPHAR/BPS Guide to PHARMACOLOGY
2062
Clinical resources for MAP2K1
OMIM
176872
LRG
LRG_725 Curated
LSDB
The Globin Gene Server Curated
GenCC
HGNC:6840
MedlinePlus
Search via MAP2K1
DECIPHER
Search via MAP2K1
ClinGen
Search via HGNC:6840
Genetic Testing Registry
Search via NCBI Gene ID 5604
ClinVar
Search via NCBI Gene ID 5604
dbVar
Search via NCBI Gene ID 5604
Orphanet
123135
COSMIC
MAP2K1
Other resources for MAP2K1
AmiGO
Search via Q02750
QuickGO
Search via Q02750
BioGPS
Search via NCBI Gene ID 5604
GeneCards
Search via HGNC:6840
Monarch
Search via HGNC:6840
WikiGenes
Search via NCBI Gene ID 5604
References for MAP2K1