All download files including the archive files are now in a publicly accessible Google Storage Bucket. Downloads page links have been updated.

Not found

Our G-nome assistant hasn't been able to find this symbol report. Please check the URL or use our search to find what you are looking for.

Symbol report for HLCS

HGNC data for HLCS

Approved symbol
HLCS
Approved name

holocarboxylase synthetase

Locus type
gene with protein product
HGNC ID
HGNC:4976
Symbol status
Approved
Previous names
holocarboxylase synthetase (biotin-[proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase)
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
Alias symbols
HCS
Alias names
biotin--protein ligase
Chromosomal location
21q22.13
Gene resources for HLCS
Ensembl
ENSG00000159267 Curated
Ensembl region in detailEnsembl gene sequence
NCBI Gene
3141 Curated
UCSC
uc002yvs.4
Alliance of Genome Resources
HGNC:4976
Nucleotide resources for HLCS
MANE Select
NM_001352514.2
ENST00000674895.3
RefSeq
NM_000411
NCBI sequence viewer
Protein resources for HLCS
UniProt/Swiss-Prot
P50747
InterProPDBeReactome
AlphaFold
AF-P50747-F1
Enzyme Commission
6.3.4.9 Curated
ExpasyBRENDAKEGGIntEnzIUBMB Enzyme Nomenclature
6.3.4.10 Curated
ExpasyBRENDAKEGGIntEnzIUBMB Enzyme Nomenclature
6.3.4.11 Curated
ExpasyBRENDAKEGGIntEnzIUBMB Enzyme Nomenclature
6.3.4.15 Curated
ExpasyBRENDAKEGGIntEnzIUBMB Enzyme Nomenclature
Orthologs from selected species for HLCS
Bos taurus
HLCS VGNC:50274 VGNC
Canis familiaris
HLCS VGNC:50300 VGNC
Equus caballus
HLCS VGNC:59256 VGNC
Felis catus
HLCS VGNC:67588 VGNC
Macaca mulatta
HLCS VGNC:73477 VGNC
Mus musculus
Hlcs MGI:894646 Curated
Pan troglodytes
HLCS VGNC:6592 VGNC
Rattus norvegicus
Hlcs RGD:1565360
Sus scrofa
HLCS VGNC:88895 VGNC
Clinical resources for HLCS
OMIM
609018
GenCC
HGNC:4976
MedlinePlus
Search via HLCS
DECIPHER
Search via HLCS
ClinGen
Search via HGNC:4976
Genetic Testing Registry
Search via NCBI Gene ID 3141
ClinVar
Search via NCBI Gene ID 3141
dbVar
Search via NCBI Gene ID 3141
Orphanet
122430
Other resources for HLCS
AmiGO
Search via P50747
QuickGO
Search via P50747
BioGPS
Search via NCBI Gene ID 3141
GeneCards
Search via HGNC:4976
Monarch
Search via HGNC:4976
WikiGenes
Search via NCBI Gene ID 3141
References for HLCS