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Symbol report for DOT1L

HGNC data for DOT1L

Approved symbol
DOT1L
Approved name

DOT1 like histone lysine methyltransferase

Locus type
gene with protein product
HGNC ID
HGNC:24948
Symbol status
Approved
Previous names
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
Alias symbols
KIAA1814
DOT1
KMT4
Alias names
histone methyltransferase DOT1L
Chromosomal location
19p13.3
Gene groups
Gene resources for DOT1L
Ensembl
ENSG00000104885 Curated
Ensembl region in detailEnsembl gene sequence
NCBI Gene
84444 Curated
UCSC
uc002lvb.4
Alliance of Genome Resources
HGNC:24948
Nucleotide resources for DOT1L
MANE Select
NM_032482.3
ENST00000398665.8
INSDC
AF509504 Curated
ENAGenBankDDBJ
RefSeq
NM_032482 Curated
NCBI sequence viewer
CCDS
CCDS42460 Curated
CCDS92483 Curated
Protein resources for DOT1L
UniProt/Swiss-Prot
Q8TEK3
InterProPDBeReactome
AlphaFold
AF-Q8TEK3-F1
Enzyme Commission
2.1.1.360 Curated
ExpasyBRENDAKEGGIntEnzIUBMB Enzyme Nomenclature
Orthologs from selected species for DOT1L
Bos taurus
DOT1L VGNC:50607 VGNC
Canis familiaris
DOT1L VGNC:54298 VGNC
Equus caballus
DOT1L VGNC:50588 VGNC
Felis catus
DOT1L VGNC:61591 VGNC
Macaca mulatta
DOT1L VGNC:71901 VGNC
Mus musculus
Dot1l MGI:2143886 Curated
Pan troglodytes
DOT1L VGNC:7478 VGNC
Rattus norvegicus
Dot1l RGD:1306644
Sus scrofa
DOT1L VGNC:87410 VGNC
Specialist resources for DOT1L
IUPHAR/BPS Guide to PHARMACOLOGY
2650
Clinical resources for DOT1L
OMIM
607375
MedlinePlus
Search via DOT1L
DECIPHER
Search via DOT1L
ClinGen
Search via HGNC:24948
Genetic Testing Registry
Search via NCBI Gene ID 84444
ClinVar
Search via NCBI Gene ID 84444
dbVar
Search via NCBI Gene ID 84444
Orphanet
470238
Other resources for DOT1L
AmiGO
Search via Q8TEK3
QuickGO
Search via Q8TEK3
BioGPS
Search via NCBI Gene ID 84444
GeneCards
Search via HGNC:24948
Monarch
Search via HGNC:24948
WikiGenes
Search via NCBI Gene ID 84444
References for DOT1L