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Symbol report for CASP8

Stable symbol

HGNC data for CASP8

Approved symbol
CASP8
Approved name

caspase 8

Locus type
gene with protein product
HGNC ID
HGNC:1509
Symbol status
Approved
Previous names
caspase 8, apoptosis-related cysteine protease
caspase 8, apoptosis-related cysteine peptidase
Alias symbols
MCH5
MACH
FLICE
Casp-8
Chromosomal location
2q33.1
Gene groups
Gene resources for CASP8
Ensembl
ENSG00000064012 Curated
Ensembl region in detailEnsembl gene sequence
NCBI Gene
841 Curated
UCSC
uc002uxt.2
Alliance of Genome Resources
HGNC:1509
Nucleotide resources for CASP8
MANE Select
NM_001372051.1
ENST00000673742.1
INSDC
U60520 Curated
ENAGenBankDDBJ
RefSeq
NM_001228 Curated
NCBI sequence viewer
Protein resources for CASP8
UniProt/Swiss-Prot
Q14790
InterProPDBeReactome
AlphaFold
AF-Q14790-F1
Enzyme Commission
3.4.22.61 Curated
ExpasyBRENDAKEGGIntEnzIUBMB Enzyme Nomenclature
Orthologs from selected species for CASP8
Bos taurus
CASP8 VGNC:26784 VGNC
Canis familiaris
CASP8 VGNC:38736 VGNC
Equus caballus
CASP8 VGNC:16071 VGNC
Felis catus
CASP8 VGNC:60384 VGNC
Macaca mulatta
CASP8 VGNC:70547 VGNC
Mus musculus
Casp8 MGI:1261423 Curated
Pan troglodytes
CASP8 VGNC:119 VGNC
Rattus norvegicus
Casp8 RGD:620945
Sus scrofa
CASP8 VGNC:95639 VGNC
Specialist resources for CASP8
IUPHAR/BPS Guide to PHARMACOLOGY
1624
MEROPS
C14.009
Clinical resources for CASP8
OMIM
601763
LRG
LRG_34 Curated
LSDB
CASP8base: Mutation registry for Caspase 8 deficiency Curated
GenCC
HGNC:1509
MedlinePlus
Search via CASP8
DECIPHER
Search via CASP8
ClinGen
Search via HGNC:1509
Genetic Testing Registry
Search via NCBI Gene ID 841
ClinVar
Search via NCBI Gene ID 841
dbVar
Search via NCBI Gene ID 841
Orphanet
138851
COSMIC
CASP8
Other resources for CASP8
AmiGO
Search via Q14790
QuickGO
Search via Q14790
BioGPS
Search via NCBI Gene ID 841
GeneCards
Search via HGNC:1509
Monarch
Search via HGNC:1509
WikiGenes
Search via NCBI Gene ID 841
References for CASP8