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Symbol report for TYK2

Stable symbol

HGNC data for TYK2

Approved symbol
TYK2
Approved name

tyrosine kinase 2

Locus type
gene with protein product
HGNC ID
HGNC:12440
Symbol status
Approved
Alias symbols
JTK1
Chromosomal location
19p13.2
Gene groups
Gene resources for TYK2
Ensembl
ENSG00000105397 Curated
Ensembl region in detailEnsembl gene sequence
NCBI Gene
7297 Curated
UCSC
uc002moc.5
Alliance of Genome Resources
HGNC:12440
Nucleotide resources for TYK2
MANE Select
NM_003331.5
ENST00000525621.6
RefSeq
NM_001385197
NCBI sequence viewer
Protein resources for TYK2
UniProt/Swiss-Prot
P29597
InterProPDBeReactome
AlphaFold
AF-P29597-F1
Enzyme Commission
2.7.10.1 Curated
ExpasyBRENDAKEGGIntEnzIUBMB Enzyme Nomenclature
Orthologs from selected species for TYK2
Bos taurus
TYK2 VGNC:36548 VGNC
Canis familiaris
TYK2 VGNC:48024 VGNC
Equus caballus
TYK2 VGNC:56801 VGNC
Felis catus
TYK2 VGNC:66736 VGNC
Macaca mulatta
TYK2 VGNC:78680 VGNC
Mus musculus
Tyk2 MGI:1929470 Curated
Pan troglodytes
TYK2 VGNC:2210 VGNC
Rattus norvegicus
Tyk2 RGD:2320469
Sus scrofa
TYK2 VGNC:94615 VGNC
Specialist resources for TYK2
IUPHAR/BPS Guide to PHARMACOLOGY
2269
Clinical resources for TYK2
OMIM
176941
LRG
LRG_121 Curated
LSDB
TYK2base: Mutation registry for TYK2 deficiency Curated
GenCC
HGNC:12440
MedlinePlus
Search via TYK2
DECIPHER
Search via TYK2
ClinGen
Search via HGNC:12440
Genetic Testing Registry
Search via NCBI Gene ID 7297
ClinVar
Search via NCBI Gene ID 7297
dbVar
Search via NCBI Gene ID 7297
Orphanet
159075
Other resources for TYK2
AmiGO
Search via P29597
QuickGO
Search via P29597
BioGPS
Search via NCBI Gene ID 7297
GeneCards
Search via HGNC:12440
Monarch
Search via HGNC:12440
WikiGenes
Search via NCBI Gene ID 7297
References for TYK2