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Symbol report for TOP2A

HGNC data for TOP2A

Approved symbol
TOP2A
Approved name

DNA topoisomerase II alpha

Locus type
gene with protein product
HGNC ID
HGNC:11989
Symbol status
Approved
Previous symbols
TOP2
Previous names
topoisomerase (DNA) II alpha 170kDa
Alias symbols
TOP2alpha
TOPIIA
Chromosomal location
17q21.2
Gene groups
Gene resources for TOP2A
Ensembl
ENSG00000131747 Curated
Ensembl region in detailEnsembl gene sequence
NCBI Gene
7153 Curated
UCSC
uc002huq.4
Alliance of Genome Resources
HGNC:11989
Nucleotide resources for TOP2A
MANE Select
NM_001067.4
ENST00000423485.6
RefSeq
NM_001067
NCBI sequence viewer
CCDS
CCDS45672 Curated
Protein resources for TOP2A
UniProt/Swiss-Prot
P11388
InterProPDBeReactome
AlphaFold
AF-P11388-F1
Enzyme Commission
5.6.2.1 Curated
ExpasyBRENDAKEGGIntEnzIUBMB Enzyme Nomenclature
Orthologs from selected species for TOP2A
Bos taurus
TOP2A VGNC:49583 VGNC
Canis familiaris
TOP2A VGNC:49098 VGNC
Equus caballus
TOP2A VGNC:50516 VGNC
Felis catus
TOP2A VGNC:66448 VGNC
Macaca mulatta
TOP2A VGNC:78620 VGNC
Mus musculus
Top2a MGI:98790 Curated
Pan troglodytes
TOP2A VGNC:9732 VGNC
Rattus norvegicus
Top2a RGD:62048
Sus scrofa
TOP2A VGNC:94310 VGNC
Specialist resources for TOP2A
IUPHAR/BPS Guide to PHARMACOLOGY
2637
Clinical resources for TOP2A
OMIM
126430
MedlinePlus
Search via TOP2A
DECIPHER
Search via TOP2A
ClinGen
Search via HGNC:11989
Genetic Testing Registry
Search via NCBI Gene ID 7153
ClinVar
Search via NCBI Gene ID 7153
dbVar
Search via NCBI Gene ID 7153
Orphanet
353516
Other resources for TOP2A
AmiGO
Search via P11388
QuickGO
Search via P11388
BioGPS
Search via NCBI Gene ID 7153
GeneCards
Search via HGNC:11989
Monarch
Search via HGNC:11989
WikiGenes
Search via NCBI Gene ID 7153