Description
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2; involved in glycolysis and gluconeogenesis; tetramer that catalyzes reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in cytoplasm and cell wall; protein abundance increases in response to DNA replication stress; GAPDH-derived antimicrobial peptides are active against a wide variety of wine-related yeasts and bateria; TDH2 has a paralog, TDH3, that arose from the whole genome duplication [Source:SGD;Acc:S000003769]
Gene Synonyms
GAPDH, GLD2
Location
Chromosome X: 453,683-454,681 reverse strand.
R64-1-1:BK006943.2
About this gene
This gene has 1 transcript (splice variant), 500 orthologues and 2 paralogues.
Transcripts
