Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc2p; mutations in the human homolog are associated with lactic acidosis; PYC1 has a paralog, PYC2, that arose from the whole genome duplication [Source:SGD;Acc:S000003030]
Chromosome VII: 385,196-388,732 forward strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 236 orthologues and 3 paralogues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YGL062W_mRNA | PYC1 | 3537 | 1178aa | YGL062W | Protein coding | P11154 | Ensembl Canonical, |