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DP00086 - Cellular tumor antigen p53

Gene TP53 (P53)
Sequence length 393
Disorder content 87.8%
Cross references UniProtKB:P04637, MobiDB:P04637
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DP00086r013 Structural state
Term disorder, IDPO:00076
Fragment 1 - 93
Evidence nuclear magnetic resonance spectroscopy evidence used in manual assertion, ECO:0006165
Reference Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain. Wells M, Tidow H, Rutherford TJ, Markwick P, Jensen MR, Mylonas E, Svergun DI, Blackledge M, Fersht AR. Proc Natl Acad Sci U S A, 2008, pmid:18391200
Statements Results "RDC analysis showed that the isolated domain p53(1–93) was an IDP with two regions of nascent secondary structure."