Relation Results

Summary

Name Liprin-alpha
Primary ID SIGNOR-PF82
Type protein family
Formed by PPFIA1, PPFIA2, PPFIA3
Relations 1

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Type: Score: Layout: SPV 
0.2Liprin-alphaKIF1A

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Relations
Regulator
Mechanism
target
score ℹ
+ Liprin-alphaup-regulates activity img/direct-activation.png binding KIF1A 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-266892 Rattus norvegicus Pyramidal Neuron
pmid sentence
Kinesin-3 Family Member KIF1A Interacts with Liprin-α and TANC2. TANC2 and Liprin-α Recruit KIF1A-Driven DCVs in Dendritic Spines. Upon Ca2+/CaM binding, KIF1A is activated, allowing for DCV loading and motility. KIF1A-driven DCVs are recruited in dendritic spines by liprin-α and TANC2, which ensure a precise mechanism of synaptic tagging for the vesicles.
Publications: 1 Organism: Rattus Norvegicus
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