Relation Results

Summary

Name Cadherins
Primary ID SIGNOR-PF71
Type protein family
Formed by CDH1, CDH10, CDH11, CDH12, CDH13, CDH15, CDH16, CDH17, CDH18, CDH19, CDH2, CDH20, CDH22, CDH23, CDH24, CDH3, CDH4, CDH5, CDH6, CDH7, CDH8, CDH9
Relations 2
Pathways Neurotransmitters release

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Type: Score: Layout: SPV 
0.20.8CadherinsCTNNB1calcium(2+)

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Relations
Regulator
Mechanism
target
score ℹ
+ Cadherinsup-regulates activity img/direct-activation.png binding CTNNB1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-265812 Homo sapiens
pmid sentence
At its C-terminus, cadherin interacts with β-catenin, which dynamically associates with α-catenin, a direct binding partner of filamentous actin
Publications: 1 Organism: Homo Sapiens
Pathways:Neurotransmitters release
+ calcium(2+)up-regulates activity img/direct-activation.png chemical activation Cadherins 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-265811 Homo sapiens
pmid sentence
Cadherins are Ca(2+)-dependent cell-cell adhesion molecules that play critical roles in animal morphogenesis.
Publications: 1 Organism: Homo Sapiens
Pathways:Neurotransmitters release
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