| + |
ODAD4 | up-regulates activity 
binding
|
Axonemal_Dynein |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265546 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 33347437 |
CFAP53 likely facilitates the transport of TTC25 and the dyneins into cilia. CFAP53 at the centriolar satellites may form a complex with TTC25 and ODAs, including DNAH5 and DNAH11, and regulate their trafficking into the cilium (Fig 10B). It also interacts with ODA proteins including dynein heavy chains such as DNAH11 and possibly DNAH5/9. CFAP53 likely facilitates the transport of TTC25 and the dyneins into cilia. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| Tissue: |
Embryo |
| + |
FOXJ1 | up-regulates quantity by expression
transcriptional regulation
|
Axonemal_Dynein |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266939 |
|
|
Homo sapiens |
Basal Cell |
| pmid |
sentence |
| 23822649 |
FOXJ1 expression in basal cells induced the expression of a panel of cilia-associated genes, including centrin 2 (CETN2); dynein, axonemal, heavy chain 11 (DNAH11); dynein, axonemal, intermediate chain 1 (DNAI1); dynein, axonemal, light intermediate chain 1 (DNALI1); EF-hand domain, C-terminal, containing 1 (EFHC1); sperm associated antigen 6 (SPAG6); tektin 1 (TEKT1), TEKT2 and tubulin, alpha 1a (TUBA1A; Figure 3C and Additional file 2: Table S1). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Axonemal_Dynein | up-regulates 
|
Cilium_movement |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265021 |
|
|
|
|
| pmid |
sentence |
| 16440056 |
Axonemal dyneins are responsible for the movement of cilia and flagella. |
|
| Publications: |
1 |
| + |
CFAP53 | up-regulates activity
binding
|
Axonemal_Dynein |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265547 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 33347437 |
CFAP53 associates with axonemal microtubules of tracheal cilia and interacts with dynein proteins and the docking complex (DC) |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| Tissue: |
Embryo |
| + |
Axonemal_Dynein | up-regulates
|
Microtubule-based_movement |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265020 |
|
|
|
|
| pmid |
sentence |
| 16440056 |
Dyneins are large multi-subunit protein complexes that undertake a wide range of roles within the cell. They are adenosine triphosphate (ATP)–driven, microtubule minus-end-directed molecular motors that can be divided, based on function, into two classes: axonemal and cytoplasmic dyneins |
|
| Publications: |
1 |
3.0
Axonemal_Dynein