Relation Results

Summary

Name Kindlin
Primary ID SIGNOR-PF48
Type protein family
Formed by FERMT1, FERMT2, FERMT3
Relations 31
Pathways Integrin Signaling

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Type: Score: Layout: SPV 
0.4550.20.20.4080.4750.4080.4550.4440.410.3630.20.20.3660.3430.3730.20.390.20.20.3470.4080.3240.3580.4140.4120.3320.20.4080.3560.20.439KindlinA11/b1 integrinITGB1ITGB6A9/b1 integrinAv/b3 integrinA3/b1 integrinA10/b1 integrinAL/b2 integrinAD/b2 integrinA2/b1 integrinITGB2ITGB8Av/b2 integrinAv/b6 integrinA5/b1 integrinITGB7AE/b7 integrinITGB5ITGB4A6/b4 integrinA6/b1 integrinA4/b7 integrinA4/b1 integrinAM/b2 integrinAX/b2 integrinAv/b8 integrinITGB3A8/b1 integrinAv/b5 integrinFBLIM1A1/b1 integrin

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Relations
Regulator
Mechanism
target
score ℹ
+ Kindlinup-regulates activity img/direct-activation.png binding A11/b1 integrin 0.455
Identifier Residue Sequence Organism Cell Line
SIGNOR-259022 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding ITGB1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-258999 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
Pathways:Integrin Signaling
+ Kindlinup-regulates activity img/direct-activation.png binding ITGB6 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-259007 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding A9/b1 integrin 0.408
Identifier Residue Sequence Organism Cell Line
SIGNOR-259020 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding Av/b3 integrin 0.475
Identifier Residue Sequence Organism Cell Line
SIGNOR-259001 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
Pathways:Integrin Signaling
+ Kindlinup-regulates activity img/direct-activation.png binding A3/b1 integrin 0.408
Identifier Residue Sequence Organism Cell Line
SIGNOR-259015 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding A10/b1 integrin 0.455
Identifier Residue Sequence Organism Cell Line
SIGNOR-259021 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding AL/b2 integrin 0.444
Identifier Residue Sequence Organism Cell Line
SIGNOR-259024 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding AD/b2 integrin 0.41
Identifier Residue Sequence Organism Cell Line
SIGNOR-259028 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding A2/b1 integrin 0.363
Identifier Residue Sequence Organism Cell Line
SIGNOR-259014 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding ITGB2 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-259023 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding ITGB8 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-259012 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding Av/b2 integrin 0.366
Identifier Residue Sequence Organism Cell Line
SIGNOR-259027 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding Av/b6 integrin 0.343
Identifier Residue Sequence Organism Cell Line
SIGNOR-259008 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding A5/b1 integrin 0.373
Identifier Residue Sequence Organism Cell Line
SIGNOR-259017 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding ITGB7 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-259009 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding AE/b7 integrin 0.39
Identifier Residue Sequence Organism Cell Line
SIGNOR-259010 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding ITGB5 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-259005 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding ITGB4 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-259003 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
Pathways:Integrin Signaling
+ Kindlinup-regulates activity img/direct-activation.png binding A6/b4 integrin 0.347
Identifier Residue Sequence Organism Cell Line
SIGNOR-259004 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
Pathways:Integrin Signaling
+ Kindlinup-regulates activity img/direct-activation.png binding A6/b1 integrin 0.408
Identifier Residue Sequence Organism Cell Line
SIGNOR-259018 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
Pathways:Integrin Signaling
+ Kindlinup-regulates activity img/direct-activation.png binding A4/b7 integrin 0.324
Identifier Residue Sequence Organism Cell Line
SIGNOR-259011 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding A4/b1 integrin 0.358
Identifier Residue Sequence Organism Cell Line
SIGNOR-259016 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding AM/b2 integrin 0.414
Identifier Residue Sequence Organism Cell Line
SIGNOR-259025 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding AX/b2 integrin 0.412
Identifier Residue Sequence Organism Cell Line
SIGNOR-259026 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding Av/b8 integrin 0.332
Identifier Residue Sequence Organism Cell Line
SIGNOR-259013 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding ITGB3 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-259002 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
Pathways:Integrin Signaling
+ Kindlinup-regulates activity img/direct-activation.png binding A8/b1 integrin 0.408
Identifier Residue Sequence Organism Cell Line
SIGNOR-259019 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding Av/b5 integrin 0.356
Identifier Residue Sequence Organism Cell Line
SIGNOR-259006 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
+ Kindlinup-regulates activity img/direct-activation.png binding FBLIM1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269956 Mus musculus NIH-3T3 Cell
pmid sentence
Kindlin binds migfilin tandem LIM domains and regulates migfilin focal adhesion localization and recruitment dynamics. Two integrin-binding proteins present in FAs, kindlin-1 and kindlin-2, are important for integrin activation, FA formation, and signaling. By binding filamin, migfilin provides a link between kindlin and the actin cytoskeleton.
Publications: 1 Organism: Mus Musculus
+ Kindlinup-regulates activity img/direct-activation.png binding A1/b1 integrin 0.439
Identifier Residue Sequence Organism Cell Line
SIGNOR-259000 Homo sapiens
pmid sentence
Kindlins bind with β-integrin cytoplasmic tails and execute broad biological functions including directed cell migration, proliferation, differentiation and survival.
Publications: 1 Organism: Homo Sapiens
Pathways:Integrin Signaling
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