Relation Results

Summary

Name Neuregulin
Primary ID SIGNOR-PF37
Type protein family
Formed by NRG1, NRG2, NRG3, NRG4
Relations 2
Pathways ErbB receptors in cancer

Viewer

Type: Score: Layout: SPV 
0.9070.2NeuregulinErbB receptor familyERBB4

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations
Regulator
Mechanism
target
score ℹ
+ Neuregulinup-regulates activity img/direct-activation.png binding ErbB receptor family 0.907
Identifier Residue Sequence Organism Cell Line
SIGNOR-256161 Homo sapiens
pmid sentence
The neuregulin family consists of four genes, NRG1-4 which can each encode products containing a domain related to the epidermal growth factor family of ligands. they may be released by regulated proteolysis to act as soluble proteins which can interact and activate members of the EGF receptor family of receptor tyrosine kinases
Publications: 1 Organism: Homo Sapiens
Pathways:ErbB receptors in cancer
+ Neuregulinup-regulates img/direct-activation.png binding ERBB4 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-269970 Homo sapiens
pmid sentence
The neuregulins (also called heregulins and neu differentiation factors) nrg-1 and nrg-2 bind erbb-3 and erbb-4;and nrg-3 and nrg-4 bind erbb-4.
Publications: 1 Organism: Homo Sapiens
a simple tooltip