Relation Results

Summary

Name E2 conjugating enzyme
Primary ID SIGNOR-PF105
Type protein family
Formed by BIRC6, UBE2A, UBE2B, UBE2C, UBE2D1, UBE2D2, UBE2D3, UBE2D4, UBE2E1, UBE2E2, UBE2E3, UBE2G1, UBE2G2, UBE2H, UBE2I, UBE2J1, UBE2J2, UBE2K, UBE2L3, UBE2L5, UBE2L6, UBE2M, UBE2N, UBE2NL, UBE2Q1, UBE2Q2, UBE2R2, UBE2S, UBE2T, UBE2U, UBE2V1, UBE2V2, UBE2W, UBE2Z
Relations 3
Pathways Ubiquitin activation

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Type: Score: Layout: SPV 
0.20.20.2Ub:E1 (UBA1 substrate)E2 conjugating enzymeUb:E2Ub:E1 (UBA6 substrate)

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Relations
Regulator
Mechanism
target
score ℹ
+ Ub:E1 (UBA1 substrate)up-regulates activity img/direct-activation.png ubiquitination E2 conjugating enzyme 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-270840 Homo sapiens
pmid sentence
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t
Publications: 1 Organism: Homo Sapiens
Pathways:Ubiquitin activation
+ E2 conjugating enzymeform complex img/form-complex.png ubiquitination Ub:E2 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-270842 Homo sapiens
pmid sentence
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t
Publications: 1 Organism: Homo Sapiens
Pathways:Ubiquitin activation
+ Ub:E1 (UBA6 substrate)up-regulates activity img/direct-activation.png ubiquitination E2 conjugating enzyme 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-270841 Homo sapiens
pmid sentence
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t
Publications: 1 Organism: Homo Sapiens
Pathways:Ubiquitin activation
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