Relation Results

Summary

Name DNA polymerase alpha:primase complex
Primary ID SIGNOR-C262
Links CPX-2087
Type complex
Formed by POLA1, POLA2, DNA primase complex
Relations 4

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Type: Score: Layout: SPV 
0.980.980.9850.7POLA1DNA polymerase alpha:primase complexPOLA2DNA primase complexDNA_replication

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Relations
Regulator
Mechanism
target
score ℹ
+ POLA1form complex img/form-complex.png binding DNA polymerase alpha:primase complex 0.98
Identifier Residue Sequence Organism Cell Line
SIGNOR-261343 in vitro
pmid sentence
At the replication fork, primase is present in a constitutive complex with DNA polymerase α (Pol α), which extends the RNA primer with deoxynucleotides and makes the resulting RNA–DNA primer available to the leading- and lagging-strand polymerases, Pols ε and δ, for processive elongation 
Publications: 1 Organism: In Vitro
+ POLA2form complex img/form-complex.png binding DNA polymerase alpha:primase complex 0.98
Identifier Residue Sequence Organism Cell Line
SIGNOR-261342 in vitro
pmid sentence
At the replication fork, primase is present in a constitutive complex with DNA polymerase α (Pol α), which extends the RNA primer with deoxynucleotides and makes the resulting RNA–DNA primer available to the leading- and lagging-strand polymerases, Pols ε and δ, for processive elongation 
Publications: 1 Organism: In Vitro
+ DNA primase complexform complex img/form-complex.png binding DNA polymerase alpha:primase complex 0.985
Identifier Residue Sequence Organism Cell Line
SIGNOR-261341 in vitro
pmid sentence
At the replication fork, primase is present in a constitutive complex with DNA polymerase α (Pol α), which extends the RNA primer with deoxynucleotides and makes the resulting RNA–DNA primer available to the leading- and lagging-strand polymerases, Pols ε and δ, for processive elongation 
Publications: 1 Organism: In Vitro
+ DNA polymerase alpha:primase complexup-regulates img/indirect-activation.png DNA_replication 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-261344
pmid sentence
At the replication fork, primase is present in a constitutive complex with DNA polymerase α (Pol α), which extends the RNA primer with deoxynucleotides and makes the resulting RNA–DNA primer available to the leading- and lagging-strand polymerases, Pols ε and δ, for processive elongation 
Publications: 1
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