MeSH Browser

MeSH Heading: MEF2 Transcription Factors
Tree Number(s): D12.776.210.500.570.294; D12.776.260.103.750.294; D12.776.260.400.249.624; D12.776.930.125.750.294; D12.776.930.397.700
Unique ID: D064326
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D064326
Scope Note: Activating transcription factors of the MADS family which bind a specific sequence element (MEF2 element) in many muscle-specific genes and are involved in skeletal and cardiac myogenesis, neuronal differentiation and survival/apoptosis.
Entry Term(s): MEF2 Proteins; MEF2A Protein; MEF2A Transcription Factor; MEF2B Protein; MEF2B Transcription Factor; MEF2C Protein; MEF2C Transcription Factor; MEF2D Protein; MEF2D Transcription Factor; Muscle Enhancer Factor-2; Muscle Enhancer Factor-2A; Muscle Enhancer Factor-2B; Muscle Enhancer Factor-2C; Muscle Enhancer Factor-2D; Muscle-Specific Enhancer Factor-2; Muscle-Specific Enhancer Factor-2A; Muscle-Specific Enhancer Factor-2B; Muscle-Specific Enhancer Factor-2C; Muscle-Specific Enhancer Factor-2D; Myocyte Enhancer Factor 2; Myocyte Enhancer Factor 2A; Myocyte Enhancer Factor 2B; Myocyte Enhancer Factor 2C; Myocyte Enhancer Factor 2D; Myocyte-Specific Enhancer Factor 2; Myocyte-Specific Enhancer Factor 2A; Myocyte-Specific Enhancer Factor 2B; Myocyte-Specific Enhancer Factor 2C; Myocyte-Specific Enhancer Factor 2D; Myocyte-Specific Enhancer-Binding Factor 2; Myocyte-Specific Enhancer-Binding Factor 2A; Myocyte-Specific Enhancer-Binding Factor 2B; Myocyte-Specific Enhancer-Binding Factor 2C; Myocyte-Specific Enhancer-Binding Factor 2D; Serum Response Factor-Like Protein 1; Serum Response Factor-Like Protein 2
Registry Number: 0
Public MeSH Note: 2014; was indexed under MYOGENIC REGULATORY FACTORS 2004-2013; TRANSCRIPTION FACTORS 1992-2005; MADS DOMAIN PROTEINS 2005-2013
History Note: 2014
Date Established: 2014/01/01
Date of Entry: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Contractile Proteins [D12.776.210]
    - Muscle Proteins [D12.776.210.500]
      - Myogenic Regulatory Factors [D12.776.210.500.570]
        
        MEF2 Transcription Factors [D12.776.210.500.570.294]
        
        MyoD Protein [D12.776.210.500.570.590]
        
        Myogenic Regulatory Factor 5 [D12.776.210.500.570.595]
        
        Myogenin [D12.776.210.500.570.600]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - DNA-Binding Proteins [D12.776.260]
    - Basic Helix-Loop-Helix Transcription Factors [D12.776.260.103]
      - Myogenic Regulatory Factors [D12.776.260.103.750]
        
        MEF2 Transcription Factors [D12.776.260.103.750.294]
        
        MyoD Protein [D12.776.260.103.750.590]
        
        Myogenic Regulatory Factor 5 [D12.776.260.103.750.595]
        
        Myogenin [D12.776.260.103.750.600]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - DNA-Binding Proteins [D12.776.260]
    - Homeodomain Proteins [D12.776.260.400]
      - MADS Domain Proteins [D12.776.260.400.249]
        
        AGAMOUS Protein, Arabidopsis [D12.776.260.400.249.249]
        
        DEFICIENS Protein [D12.776.260.400.249.374]
        
        MEF2 Transcription Factors [D12.776.260.400.249.624]
        
        Serum Response Factor [D12.776.260.400.249.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Transcription Factors [D12.776.930]
    - Basic Helix-Loop-Helix Transcription Factors [D12.776.930.125]
      - Myogenic Regulatory Factors [D12.776.930.125.750]
        
        MEF2 Transcription Factors [D12.776.930.125.750.294]
        
        MyoD Protein [D12.776.930.125.750.590]
        
        Myogenic Regulatory Factor 5 [D12.776.930.125.750.595]
        
        Myogenin [D12.776.930.125.750.600]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Transcription Factors [D12.776.930]
    - MADS Domain Proteins [D12.776.930.397]

MEF2 Transcription Factors Preferred

Concept UI: M0581097
Registry Number: 0
Scope Note: Activating transcription factors of the MADS family which bind a specific sequence element (MEF2 element) in many muscle-specific genes and are involved in skeletal and cardiac myogenesis, neuronal differentiation and survival/apoptosis.
Terms: MEF2 Transcription Factors Preferred Term
Term UI T836809
Date02/05/2013
LexicalTag ACX
ThesaurusID NLM (2014); Muscle Enhancer Factor-2
Term UI T836815
Date02/05/2013
LexicalTag NON
ThesaurusID NLM (2014); Myocyte-Specific Enhancer-Binding Factor 2
Term UI T836811
Date02/05/2013
LexicalTag NON
ThesaurusID NLM (2014); Myocyte Enhancer Factor 2
Term UI T836813
Date02/05/2013
LexicalTag NON
ThesaurusID NLM (2014); Myocyte-Specific Enhancer Factor 2
Term UI T836810
Date02/05/2013
LexicalTag NON
ThesaurusID NLM (2014); MEF2 Proteins
Term UI T836814
Date02/05/2013
LexicalTag ACX
ThesaurusID NLM (2014); Muscle-Specific Enhancer Factor-2
Term UI T836812
Date02/05/2013
LexicalTag NON
ThesaurusID NLM (2014)

MEF2B Transcription Factor Narrower

MEF2D Transcription Factor Narrower

MEF2A Transcription Factor Narrower

MEF2C Transcription Factor Narrower

MEF2 Transcription Factors MeSH Descriptor Data 2024