MeSH Browser

MeSH Heading: Peroxiredoxins
Tree Number(s): D08.811.682.732.850
Unique ID: D054464
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054464
Scope Note: A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.
Entry Term(s): Alkyl Hydroperoxide Reductase; Alkyl Hydroperoxide Reductase C; Alkyl Hydroperoxide Reductase D; Alkylhydroperoxide Reductase; Peroxidoxin; Peroxiredoxin; Peroxiredoxin 1; Peroxiredoxin 2; Peroxiredoxin 4; Peroxiredoxin 5; Peroxiredoxin I; Peroxiredoxin II; Peroxiredoxin IV; Peroxiredoxin V; Peroxiredoxin-4; Protector Protein (Mixed-Function Oxidase Systems); Thiol-Specific Antioxidant Protein; Thioredoxin Peroxidase; Thioredoxin Peroxidase 1; Thioredoxin Peroxidase 2; Thioredoxin Peroxidase PMP20; Thioredoxin-Dependent Peroxide Reductase 1; Thioredoxin-Dependent Peroxide Reductase 2
Registry Number: EC 1.11.1.15
Related Numbers: EC 1.11.1.15
Public MeSH Note: 2008; PEROXIDOXIN (now PEROXIDOXINS) was indexed under PEROXIDASES 2000-2007 & under OXIDOREDUCTASES 1988-1999; PEROXIREDOXIN IV was indexed under PEROXIDASES 2000-2007
History Note: 2008(1988)
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2011/06/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Oxidoreductases [D08.811.682]
    - Peroxidases [D08.811.682.732]

Peroxiredoxins Preferred

Concept UI: M0352091
Registry Number: EC 1.11.1.15
Related Numbers: EC 1.11.1.15
Scope Note: A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.
Terms: Peroxiredoxins Preferred Term
Term UI T688896
Date01/05/2007
LexicalTag NON
ThesaurusID NLM (2008); Alkylhydroperoxide Reductase
Term UI T191346
LexicalTag NON
ThesaurusID NLM (2008); Peroxidoxin
Term UI T465079
Date10/06/2001
LexicalTag NON
ThesaurusID NLM (2008); Thioredoxin Peroxidase
Term UI T185872
LexicalTag NON
ThesaurusID NLM (2008); Protector Protein (Mixed-Function Oxidase Systems)
Term UI T185873
LexicalTag NON
ThesaurusID NLM (2008); Thiol-Specific Antioxidant Protein
Term UI T185871
LexicalTag NON
ThesaurusID NLM (2008); Alkyl Hydroperoxide Reductase
Term UI T191347
LexicalTag NON
ThesaurusID NLM (2008); Peroxiredoxin
Term UI T401485
Date12/03/1999
LexicalTag NON
ThesaurusID NLM (2008)

Alkyl Hydroperoxide Reductase D Narrower

Peroxiredoxin V Narrower

Peroxiredoxin II Narrower

Concept UI: M0429449
Registry Number: EC 1.11.1.15
Terms: Peroxiredoxin II Preferred Term
Term UI T554636
Date10/24/2003
LexicalTag NON
ThesaurusID NLM (2008); Thioredoxin Peroxidase 1
Term UI T688893
Date01/05/2007
LexicalTag NON
ThesaurusID NLM (2008); Thioredoxin-Dependent Peroxide Reductase 1
Term UI T688894
Date01/05/2007
LexicalTag NON
ThesaurusID NLM (2008); Peroxiredoxin 2
Term UI T501930
Date06/29/2002
LexicalTag NON
ThesaurusID NLM (2008)

Peroxiredoxin IV Narrower

Alkyl Hydroperoxide Reductase C Narrower

Peroxiredoxin I Narrower

Concept UI: M0352092
Registry Number: EC 1.11.1.15
Terms: Peroxiredoxin I Preferred Term
Term UI T497662
Date06/10/2002
LexicalTag NON
ThesaurusID NLM (2008); Thioredoxin Peroxidase 2
Term UI T688891
Date01/05/2007
LexicalTag NON
ThesaurusID NLM (2008); Thioredoxin-Dependent Peroxide Reductase 2
Term UI T688892
Date01/05/2007
LexicalTag NON
ThesaurusID NLM (2008); Peroxiredoxin 1
Term UI T554641
Date10/24/2003
LexicalTag NON
ThesaurusID NLM (2008)

Peroxiredoxins MeSH Descriptor Data 2024