The tripartite motif family identifies cell compartments.
Reymond A
et al.
EMBO J 2001 May;20(9)2140-2151
EMBO J 2001 May;20(9)2140-2151
Abstract: A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a tripartite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.