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  up:title "Calcium channel gamma subunits provide insights into the evolution of this gene family." ;
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  up:title "Cardiac L-type calcium channel (Cav1.2) associates with gamma subunits." ;
  up:author "Yang L." ,
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<http://purl.uniprot.org/hgnc/13625> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/HGNC> ;
  rdfs:comment "CACNG6" .
<http://www.proteinatlas.org/ENSG00000130433> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/HPA> ;
  rdfs:comment "Group enriched (skeletal muscle, tongue)" .
<http://purl.uniprot.org/mim/606898> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/MIM> ;
  rdfs:comment "gene" .
<http://nextprot.org/rdf/entry/NX_Q9BXT2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/neXtProt> .
<http://purl.uniprot.org/opentargets/ENSG00000130433> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/OpenTargets> .
<http://purl.uniprot.org/pharmgkb/PA26020> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PharmGKB> .
<http://purl.uniprot.org/veupathdb/HostDB:ENSG00000130433> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/VEuPathDB> .
<http://purl.uniprot.org/eggnog/ENOG502QUPR> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/eggNOG> ;
  rdfs:comment "Eukaryota" .
<http://purl.uniprot.org/genetree/ENSGT00390000007786> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/GeneTree> .
<http://purl.uniprot.org/inparanoid/Q9BXT2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/InParanoid> .
<http://purl.uniprot.org/oma/PWQRCLP> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/OMA> .
<http://purl.orthodb.org/odbgroup/4230292at2759> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/OrthoDB> .
<http://purl.uniprot.org/phylomedb/Q9BXT2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PhylomeDB> .
<http://purl.uniprot.org/treefam/TF331651> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/TreeFam> .
<http://purl.uniprot.org/pathwaycommons/Q9BXT2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PathwayCommons> .
<http://identifiers.org/reactome/R-HSA-5576892> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Reactome> ;
  rdfs:comment "Phase 0 - rapid depolarisation" .
<http://identifiers.org/reactome/R-HSA-5576893> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Reactome> ;
  rdfs:comment "Phase 2 - plateau phase" .
<http://purl.uniprot.org/signalink/Q9BXT2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/SignaLink> .
<http://purl.uniprot.org/biogrid-orcs/59285> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/BioGRID-ORCS> ;
  rdfs:comment "21 hits in 1143 CRISPR screens" .
<http://purl.uniprot.org/chitars/CACNG6> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/ChiTaRS> ;
  rdfs:comment "human" .
<http://purl.uniprot.org/genomernai/59285> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/GenomeRNAi> .
<http://purl.uniprot.org/pharos/Q9BXT2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Pharos> ;
  rdfs:comment "Tdark" .
<http://purl.obolibrary.org/obo/PR_Q9BXT2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PRO> .
<http://purl.uniprot.org/rnact/Q9BXT2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/RNAct> ;
  rdfs:comment "Protein" .
<http://purl.uniprot.org/bgee/ENSG00000130433> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Bgee> ;
  rdfs:comment "Expressed in hindlimb stylopod muscle and 96 other cell types or tissues" .
<http://purl.uniprot.org/expressionatlas/Q9BXT2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/ExpressionAtlas> ;
  rdfs:comment "baseline and differential" .
<http://purl.uniprot.org/gene3d/1.20.140.150> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Gene3D> ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/Q9BXT2-1#Gene3D_1.20.140.150_match_1> .
<http://purl.uniprot.org/interpro/IPR004031> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/InterPro> ;
  rdfs:comment "PMP22/EMP/MP20/Claudin" .
<http://purl.uniprot.org/interpro/IPR008370> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/InterPro> ;
  rdfs:comment "VDCC_g6su" .
<http://purl.uniprot.org/interpro/IPR008368> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/InterPro> ;
  rdfs:comment "VDCC_gsu" .
<http://purl.uniprot.org/panther/PTHR15025> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PANTHER> ;
  rdfs:comment "VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED" ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/Q9BXT2-1#PANTHER_PTHR15025_match_1> .
<http://purl.uniprot.org/panther/PTHR15025:SF6> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PANTHER> ;
  rdfs:comment "VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-6 SUBUNIT" ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/Q9BXT2-1#PANTHER_PTHR15025:SF6_match_1> .
<http://purl.uniprot.org/pfam/PF13903> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Pfam> ;
  rdfs:comment "Claudin_2" ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/Q9BXT2-1#Pfam_PF13903_match_1> .
<http://purl.uniprot.org/prints/PR01792> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PRINTS> ;
  rdfs:comment "VDCCGAMMA" .
<http://purl.uniprot.org/prints/PR01794> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PRINTS> ;
  rdfs:comment "VDCCGAMMA6" .
<http://purl.uniprot.org/genevisible/Q9BXT2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Genevisible> ;
  rdfs:comment "HS" .
<Q9BXT2#SIP08C36093419EF7C6> rdf:type up:Structured_Name ;
  up:fullName "Voltage-dependent calcium channel gamma-6 subunit" .
<Q9BXT2#SIPE7D6CA8C6B629CC7> rdf:type up:Structured_Name ;
  up:fullName "Neuronal voltage-gated calcium channel gamma-6 subunit" .
<#_kb.Q9BXT2_up.isolatedFrom_tissue.309> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:isolatedFrom ;
  rdf:object tissue:309 ;
  up:citation citation:15489334 .
<Q9BXT2#gene-MD534D81D1A642BA63AEBCC54F61C038266> rdf:type up:Gene ;
  skos:prefLabel "CACNG6" .
<Q9BXT2#SIP363DE0D0E8D3864F> rdf:type up:Function_Annotation ;
  rdfs:comment "Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit." .
<#_0D0BC8C1641AEFC3_rdfs.comment_6DF0A6329929776C> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2#SIP363DE0D0E8D3864F> ;
  rdf:predicate rdfs:comment ;
  rdf:object "Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit." ;
  up:attribution <Q9BXT2#attribution-CA7FEC200333235A8B141A46D4A80A7A> .
<Q9BXT2#SIP89E7689413A6532C> rdf:type up:Subunit_Annotation ;
  rdfs:comment "Interacts with CACNA1C. Identified in a complex with the L-type calcium channel subunits CACNA1C, CACNA2D1 and either CACNB1 or CACNB2." .
<#_D8468D3660D8CCA3_rdfs.comment_A4D6E026BEBC30ED> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2#SIP89E7689413A6532C> ;
  rdf:predicate rdfs:comment ;
  rdf:object "Interacts with CACNA1C. Identified in a complex with the L-type calcium channel subunits CACNA1C, CACNA2D1 and either CACNB1 or CACNB2." ;
  up:attribution <Q9BXT2#attribution-CA7FEC200333235A8B141A46D4A80A7A> .
<Q9BXT2#SIP0344A467FF369ED0> rdf:type up:Subcellular_Location_Annotation ;
  up:locatedIn <Q9BXT2#SIP3F7289CEA3134E6B> .
<Q9BXT2#SIP3F7289CEA3134E6B> up:cellularComponent location:39 ;
  up:topology location:9909 .
<#_B972C61280E66017_ECA11A063956BBD5_9655A6EDB68BC0AE> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2#SIP3F7289CEA3134E6B> ;
  rdf:predicate up:cellularComponent ;
  rdf:object location:39 ;
  up:attribution <Q9BXT2#attribution-1E08366E19792EFF4051E202ECE60DF7> .
<#_B972C61280E66017_up.topology_597FCCCA90EEF434> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2#SIP3F7289CEA3134E6B> ;
  rdf:predicate up:topology ;
  rdf:object location:9909 ;
  up:attribution <Q9BXT2#attribution-1F1D235CEE6E9F517881B603655DF439> .
<Q9BXT2#SIPBCDA3C4928309358> rdf:type up:Tissue_Specificity_Annotation ;
  rdfs:comment "Detected in heart left ventricle." .
<#_8D607786DB9747DF_rdfs.comment_3F47791DB05BD57F> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2#SIPBCDA3C4928309358> ;
  rdf:predicate rdfs:comment ;
  rdf:object "Detected in heart left ventricle." ;
  up:attribution <Q9BXT2#attribution-CA7FEC200333235A8B141A46D4A80A7A> .
<Q9BXT2#SIPD4C018353F6FB634> rdf:type up:Similarity_Annotation ;
  rdfs:comment "Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily." .
<#_75A049573DE96586_rdfs.comment_DB81A650C87E21AA> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2#SIPD4C018353F6FB634> ;
  rdf:predicate rdfs:comment ;
  rdf:object "Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily." ;
  up:attribution <Q9BXT2#attribution-1F1D235CEE6E9F517881B603655DF439> .
annotation:PRO_0000164684 rdf:type up:Chain_Annotation ;
  rdfs:comment "Voltage-dependent calcium channel gamma-6 subunit" ;
  up:mass 28129 ;
  up:range range:22862430226100782tt1tt260 .
range:22862430226100782tt1tt260 rdf:type faldo:Region ;
  faldo:begin position:22862430226100782tt1 ;
  faldo:end position:22862430226100782tt260 .
position:22862430226100782tt1 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 1 ;
  faldo:reference isoform:Q9BXT2-1 .
position:22862430226100782tt260 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 260 ;
  faldo:reference isoform:Q9BXT2-1 .
<Q9BXT2#SIP515D4F98F40472C8> rdf:type up:Transmembrane_Annotation ;
  rdfs:comment "Helical" ;
  up:range range:22862430226100782tt43tt63 .
range:22862430226100782tt43tt63 rdf:type faldo:Region ;
  faldo:begin position:22862430226100782tt43 ;
  faldo:end position:22862430226100782tt63 .
position:22862430226100782tt43 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 43 ;
  faldo:reference isoform:Q9BXT2-1 .
position:22862430226100782tt63 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 63 ;
  faldo:reference isoform:Q9BXT2-1 .
<#_kb.Q9BXT2_up.annotation_B2CCA58CEF817714> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:annotation ;
  rdf:object <Q9BXT2#SIP515D4F98F40472C8> ;
  up:attribution <Q9BXT2#attribution-89AC1B682EEB440D50C4AEBB24FCA860> .
<Q9BXT2#SIPA0467EDD78E17C42> rdf:type up:Transmembrane_Annotation ;
  rdfs:comment "Helical" ;
  up:range range:22862430226100782tt143tt163 .
range:22862430226100782tt143tt163 rdf:type faldo:Region ;
  faldo:begin position:22862430226100782tt143 ;
  faldo:end position:22862430226100782tt163 .
position:22862430226100782tt143 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 143 ;
  faldo:reference isoform:Q9BXT2-1 .
position:22862430226100782tt163 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 163 ;
  faldo:reference isoform:Q9BXT2-1 .
<#_kb.Q9BXT2_up.annotation_3A84F8FEB5857EBE> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:annotation ;
  rdf:object <Q9BXT2#SIPA0467EDD78E17C42> ;
  up:attribution <Q9BXT2#attribution-89AC1B682EEB440D50C4AEBB24FCA860> .
<Q9BXT2#SIPCFF63DB3CEEF0808> rdf:type up:Transmembrane_Annotation ;
  rdfs:comment "Helical" ;
  up:range range:22862430226100782tt169tt189 .
range:22862430226100782tt169tt189 rdf:type faldo:Region ;
  faldo:begin position:22862430226100782tt169 ;
  faldo:end position:22862430226100782tt189 .
position:22862430226100782tt169 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 169 ;
  faldo:reference isoform:Q9BXT2-1 .
position:22862430226100782tt189 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 189 ;
  faldo:reference isoform:Q9BXT2-1 .
<#_kb.Q9BXT2_up.annotation_ED4AD794C91FC749> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:annotation ;
  rdf:object <Q9BXT2#SIPCFF63DB3CEEF0808> ;
  up:attribution <Q9BXT2#attribution-89AC1B682EEB440D50C4AEBB24FCA860> .
<Q9BXT2#SIPAE0635EE9E8B12EE> rdf:type up:Transmembrane_Annotation ;
  rdfs:comment "Helical" ;
  up:range range:22862430226100782tt221tt241 .
range:22862430226100782tt221tt241 rdf:type faldo:Region ;
  faldo:begin position:22862430226100782tt221 ;
  faldo:end position:22862430226100782tt241 .
position:22862430226100782tt221 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 221 ;
  faldo:reference isoform:Q9BXT2-1 .
position:22862430226100782tt241 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 241 ;
  faldo:reference isoform:Q9BXT2-1 .
<#_kb.Q9BXT2_up.annotation_888B8C95927177D5> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:annotation ;
  rdf:object <Q9BXT2#SIPAE0635EE9E8B12EE> ;
  up:attribution <Q9BXT2#attribution-89AC1B682EEB440D50C4AEBB24FCA860> .
<Q9BXT2#SIPB53E2D062C4FCEB8> rdf:type up:Region_Annotation ;
  rdfs:comment "Disordered" ;
  up:range range:22862430226100782tt14tt33 .
range:22862430226100782tt14tt33 rdf:type faldo:Region ;
  faldo:begin position:22862430226100782tt14 ;
  faldo:end position:22862430226100782tt33 .
position:22862430226100782tt14 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 14 ;
  faldo:reference isoform:Q9BXT2-1 .
position:22862430226100782tt33 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 33 ;
  faldo:reference isoform:Q9BXT2-1 .
<#_kb.Q9BXT2_up.annotation_7D600AE43B38E51B> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:annotation ;
  rdf:object <Q9BXT2#SIPB53E2D062C4FCEB8> ;
  up:attribution <Q9BXT2#attribution-260F9275F08C92D1CF2D41553CB78263> .
annotation:VAR_061540 rdf:type up:Natural_Variant_Annotation ;
  up:substitution "S" ;
  rdfs:seeAlso <http://purl.uniprot.org/dbsnp/rs12980121> ;
  up:range range:22862430226100782tt252tt252 .
<http://purl.uniprot.org/dbsnp/rs12980121> up:database <http://purl.uniprot.org/database/dbSNP> .
range:22862430226100782tt252tt252 rdf:type faldo:Region ;
  faldo:begin position:22862430226100782tt252 ;
  faldo:end position:22862430226100782tt252 .
position:22862430226100782tt252 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 252 ;
  faldo:reference isoform:Q9BXT2-1 .
<#_kb.Q9BXT2_up.classifiedWith_obo.GO_1990454> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:1990454 ;
  up:attribution <Q9BXT2#attribution-E12E237A718BD399F241A49FA12721C7> .
<#_kb.Q9BXT2_up.classifiedWith_obo.GO_0005886> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0005886 ;
  up:attribution <Q9BXT2#attribution-0EB5BB17E7E3B5C9784511A9243A1CC1> .
<#_kb.Q9BXT2_up.classifiedWith_obo.GO_0005891> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0005891 ;
  up:attribution <Q9BXT2#attribution-A12A52CCCF82666E010AA559F97C4C32> .
<#_kb.Q9BXT2_up.classifiedWith_obo.GO_0005246> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0005246 ;
  up:attribution <Q9BXT2#attribution-E12E237A718BD399F241A49FA12721C7> .
<#_kb.Q9BXT2_up.classifiedWith_obo.GO_0005245> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0005245 ;
  up:attribution <Q9BXT2#attribution-A12A52CCCF82666E010AA559F97C4C32> .
<#_kb.Q9BXT2_up.classifiedWith_obo.GO_0006816> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0006816 ;
  up:attribution <Q9BXT2#attribution-A12A52CCCF82666E010AA559F97C4C32> .
<#_kb.Q9BXT2_up.classifiedWith_obo.GO_1902514> rdf:type rdf:Statement ;
  rdf:subject <Q9BXT2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:1902514 ;
  up:attribution <Q9BXT2#attribution-B1173712290FD2B95AA2CFBCD6874F84> .
isoform:Q9BXT2-1 rdf:type up:Simple_Sequence ;
  up:modified "2001-06-01"^^xsd:date ;
  up:version 1 ;
  up:mass 28129 ;
  up:md5Checksum "696d15155546a725a89596ad709f4e29" ;
  rdf:value "MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTEFWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFFTTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGLSGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLLLTLPSWPWGSLCPKRGHRAT" .
<Q9BXT2#attribution-E12E237A718BD399F241A49FA12721C7> dcterms:creator <http://purl.uniprot.org/goa-projects/UniProtKB> ;
  up:manual true ;
  up:evidence ECO:0000314 .
<Q9BXT2#attribution-0EB5BB17E7E3B5C9784511A9243A1CC1> dcterms:creator <http://purl.uniprot.org/goa-projects/Reactome> ;
  up:manual true ;
  up:evidence ECO:0000304 .
<Q9BXT2#attribution-A12A52CCCF82666E010AA559F97C4C32> dcterms:creator <http://purl.uniprot.org/goa-projects/UniProtKB> ;
  up:manual true ;
  up:evidence ECO:0000303 .
<Q9BXT2#attribution-B1173712290FD2B95AA2CFBCD6874F84> dcterms:creator <http://purl.uniprot.org/goa-projects/GO_Central> ;
  up:manual true ;
  up:evidence ECO:0000318 .
<Q9BXT2#attribution-89AC1B682EEB440D50C4AEBB24FCA860> up:manual true ;
  up:evidence ECO:0000255 .
<Q9BXT2#attribution-260F9275F08C92D1CF2D41553CB78263> up:evidence ECO:0000256 ;
  up:source <http://purl.uniprot.org/sam/MobiDB-lite> .
<Q9BXT2#attribution-CA7FEC200333235A8B141A46D4A80A7A> up:manual true ;
  up:evidence ECO:0000269 ;
  up:source citation:21127204 .
<Q9BXT2#attribution-1F1D235CEE6E9F517881B603655DF439> up:manual true ;
  up:evidence ECO:0000305 .
<Q9BXT2#attribution-1E08366E19792EFF4051E202ECE60DF7> up:manual true ;
  up:evidence ECO:0000305 ;
  up:source citation:21127204 .