Usp48 (ubiquitin specific peptidase 48) - Rat Genome Database

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Gene: Usp48 (ubiquitin specific peptidase 48) Rattus norvegicus
Analyze
Symbol: Usp48
Name: ubiquitin specific peptidase 48
RGD ID: 735213
Description: Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in proteolysis. Located in postsynaptic membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness. Orthologous to human USP48 (ubiquitin specific peptidase 48); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: deubiquitinating enzyme 48; LOC100911993; synaptic ubiquitin-specific protease; synUSP; ubiquitin carboxyl-terminal hydrolase 48; ubiquitin carboxyl-terminal hydrolase 48-like; ubiquitin specific protease 31; ubiquitin specific protease 48; ubiquitin thioesterase 48; ubiquitin thiolesterase 48; ubiquitin-specific-processing protease 48; Usp31
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85155,083,520 - 155,151,208 (+)NCBIGRCr8
mRatBN7.25149,800,189 - 149,867,838 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5149,800,179 - 149,867,719 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5152,496,642 - 152,563,755 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05154,270,935 - 154,338,044 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05154,252,948 - 154,320,051 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05155,935,102 - 156,002,722 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5155,934,490 - 156,002,721 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05159,690,824 - 159,758,706 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45156,351,117 - 156,418,283 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15156,361,155 - 156,428,321 (+)NCBI
Celera5148,196,521 - 148,263,977 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component
cytosol  (IBA,IEA,ISO)
mitochondrion  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA)
postsynaptic membrane  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. A novel ubiquitin-specific protease, synUSP, is localized at the post-synaptic density and post-synaptic lipid raft. Tian QB, etal., J Neurochem 2003 Nov;87(3):665-75.

Genomics

Comparative Map Data
Usp48
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85155,083,520 - 155,151,208 (+)NCBIGRCr8
mRatBN7.25149,800,189 - 149,867,838 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5149,800,179 - 149,867,719 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5152,496,642 - 152,563,755 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05154,270,935 - 154,338,044 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05154,252,948 - 154,320,051 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05155,935,102 - 156,002,722 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5155,934,490 - 156,002,721 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05159,690,824 - 159,758,706 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45156,351,117 - 156,418,283 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15156,361,155 - 156,428,321 (+)NCBI
Celera5148,196,521 - 148,263,977 (+)NCBICelera
Cytogenetic Map5q36NCBI
USP48
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38121,678,298 - 21,783,149 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl121,678,298 - 21,783,606 (-)EnsemblGRCh38hg38GRCh38
GRCh37122,004,791 - 22,109,642 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36121,877,378 - 21,982,275 (-)NCBINCBI36Build 36hg18NCBI36
Build 34121,750,393 - 21,854,960NCBI
Celera120,327,493 - 20,432,623 (-)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef120,248,246 - 20,353,123 (-)NCBIHuRef
CHM1_1122,116,743 - 22,222,156 (-)NCBICHM1_1
T2T-CHM13v2.0121,502,254 - 21,607,091 (-)NCBIT2T-CHM13v2.0
Usp48
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394137,321,079 - 137,385,842 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4137,321,066 - 137,385,848 (+)EnsemblGRCm39 Ensembl
GRCm384137,594,120 - 137,658,537 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4137,593,755 - 137,658,537 (+)EnsemblGRCm38mm10GRCm38
MGSCv374137,150,104 - 137,214,452 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364135,261,884 - 135,263,495 (+)NCBIMGSCv36mm8
MGSCv364136,929,110 - 136,930,605 (+)NCBIMGSCv36mm8
Celera4135,805,168 - 135,866,736 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.0NCBI
Usp48
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554521,959,396 - 2,031,829 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554521,959,396 - 2,031,829 (-)NCBIChiLan1.0ChiLan1.0
USP48
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21205,156,524 - 205,262,860 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11204,268,387 - 204,374,735 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0120,870,023 - 20,974,251 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1121,834,330 - 21,939,250 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl121,834,638 - 21,939,250 (-)Ensemblpanpan1.1panPan2
USP48
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1277,401,101 - 77,484,139 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl277,379,440 - 77,484,089 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha273,903,899 - 73,988,493 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0277,959,166 - 78,043,360 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl277,933,330 - 78,043,356 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,778,845 - 74,862,587 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,788,846 - 75,873,345 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0276,791,995 - 76,876,474 (+)NCBIUU_Cfam_GSD_1.0
Usp48
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505841,483,213 - 41,551,300 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364747,307,439 - 7,376,074 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364747,307,475 - 7,376,086 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP48
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl679,744,932 - 79,810,220 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1679,744,928 - 79,810,241 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
USP48
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120110,854,966 - 110,958,140 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20110,854,758 - 110,960,529 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660335,331,713 - 5,436,227 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp48
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247646,528,084 - 6,610,926 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Usp48
335 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:556
Count of miRNA genes:255
Interacting mature miRNAs:334
Transcripts:ENSRNOT00000031855
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat

Markers in Region
D5Got89  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25149,802,648 - 149,802,819 (+)MAPPERmRatBN7.2
Rnor_6.05155,937,541 - 155,937,711NCBIRnor6.0
Rnor_5.05159,693,508 - 159,693,678UniSTSRnor5.0
RGSC_v3.45156,353,104 - 156,353,274UniSTSRGSC3.4
RGSC_v3.45156,353,103 - 156,353,274RGDRGSC3.4
RGSC_v3.45156,311,849 - 156,312,022RGDRGSC3.4
RGSC_v3.45156,311,850 - 156,312,022UniSTSRGSC3.4
RGSC_v3.15156,363,142 - 156,363,313RGD
Celera5148,198,502 - 148,198,672UniSTS
RH 3.4 Map51013.2UniSTS
RH 3.4 Map51013.2RGD
Cytogenetic Map5q36UniSTS
D5Kyo1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25149,859,140 - 149,859,339 (-)MAPPERmRatBN7.2
Rnor_6.01873,418,416 - 73,418,614NCBIRnor6.0
Rnor_6.05155,994,039 - 155,994,223NCBIRnor6.0
Rnor_5.05159,750,008 - 159,750,206UniSTSRnor5.0
Rnor_5.01873,094,373 - 73,094,571UniSTSRnor5.0
RGSC_v3.45156,409,585 - 156,409,783UniSTSRGSC3.4
Celera5148,255,284 - 148,255,468UniSTS
Cytogenetic Map5q36UniSTS
RH128097  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25149,867,608 - 149,867,824 (-)MAPPERmRatBN7.2
mRatBN7.25149,867,608 - 149,867,824 (+)MAPPERmRatBN7.2
Rnor_6.05156,002,493 - 156,002,708NCBIRnor6.0
Rnor_6.01873,409,930 - 73,410,145NCBIRnor6.0
Rnor_5.05159,758,477 - 159,758,692UniSTSRnor5.0
Rnor_5.01873,085,887 - 73,086,102UniSTSRnor5.0
RGSC_v3.45156,418,054 - 156,418,269UniSTSRGSC3.4
Celera5148,263,748 - 148,263,963UniSTS
RH 3.4 Map51009.7UniSTS
Cytogenetic Map5q36UniSTS
AW533548  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25149,865,636 - 149,865,843 (+)MAPPERmRatBN7.2
mRatBN7.25149,865,636 - 149,865,843 (-)MAPPERmRatBN7.2
Rnor_6.01873,411,911 - 73,412,117NCBIRnor6.0
Rnor_6.05156,000,521 - 156,000,727NCBIRnor6.0
Rnor_5.05159,756,505 - 159,756,711UniSTSRnor5.0
Rnor_5.01873,087,868 - 73,088,074UniSTSRnor5.0
RGSC_v3.45156,416,082 - 156,416,288UniSTSRGSC3.4
Celera5148,261,776 - 148,261,982UniSTS
RH 3.4 Map51010.8UniSTS
Cytogenetic Map5q36UniSTS
rs66001705  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.05155,945,375 - 155,945,375RGDRnor6.0
Rnor_5.05159,701,342 - 159,701,342RGDRnor5.0
RGSC_v3.45156,360,938 - 156,360,938RGDRGSC3.4


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 34 18 19 18 74 35 41 11
Low 17 23 23 23 8 11 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000031855   ⟹   ENSRNOP00000030008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5149,800,657 - 149,867,719 (+)Ensembl
Rnor_6.0 Ensembl5155,935,554 - 156,002,721 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077933   ⟹   ENSRNOP00000069188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5149,800,179 - 149,867,454 (+)Ensembl
Rnor_6.0 Ensembl5155,934,490 - 156,000,528 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112285   ⟹   ENSRNOP00000095844
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5149,800,657 - 149,867,719 (+)Ensembl
RefSeq Acc Id: NM_198785   ⟹   NP_942080
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85155,084,038 - 155,151,208 (+)NCBI
mRatBN7.25149,800,662 - 149,867,838 (+)NCBI
Rnor_6.05155,935,554 - 156,002,722 (+)NCBI
Rnor_5.05159,690,824 - 159,758,706 (+)NCBI
RGSC_v3.45156,351,117 - 156,418,283 (+)RGD
Celera5148,196,521 - 148,263,977 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239234   ⟹   XP_006239296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85155,083,520 - 155,151,208 (+)NCBI
mRatBN7.25149,800,189 - 149,867,838 (+)NCBI
Rnor_6.05155,935,103 - 156,002,722 (+)NCBI
Rnor_5.05159,690,824 - 159,758,706 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239235   ⟹   XP_006239297
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85155,083,520 - 155,151,208 (+)NCBI
mRatBN7.25149,800,189 - 149,867,838 (+)NCBI
Rnor_6.05155,935,103 - 156,002,722 (+)NCBI
Rnor_5.05159,690,824 - 159,758,706 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239236   ⟹   XP_006239298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85155,083,520 - 155,151,208 (+)NCBI
mRatBN7.25149,800,189 - 149,867,838 (+)NCBI
Rnor_6.05155,935,103 - 156,002,722 (+)NCBI
Rnor_5.05159,690,824 - 159,758,706 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239237   ⟹   XP_006239299
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85155,083,520 - 155,151,208 (+)NCBI
mRatBN7.25149,800,189 - 149,867,838 (+)NCBI
Rnor_6.05155,935,103 - 156,002,722 (+)NCBI
Rnor_5.05159,690,824 - 159,758,706 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039110421   ⟹   XP_038966349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85155,083,520 - 155,113,275 (+)NCBI
mRatBN7.25149,800,189 - 149,829,903 (+)NCBI
RefSeq Acc Id: XR_592739
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85155,083,520 - 155,129,724 (+)NCBI
mRatBN7.25149,800,189 - 149,853,702 (+)NCBI
Rnor_6.05155,935,102 - 155,988,600 (+)NCBI
Sequence:
RefSeq Acc Id: NP_942080   ⟸   NM_198785
- UniProtKB: Q76LT8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006239298   ⟸   XM_006239236
- Peptide Label: isoform X3
- UniProtKB: Q76LT8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006239299   ⟸   XM_006239237
- Peptide Label: isoform X4
- UniProtKB: Q76LT8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006239296   ⟸   XM_006239234
- Peptide Label: isoform X1
- UniProtKB: Q76LT8 (UniProtKB/Swiss-Prot),   A0A0G2JUQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239297   ⟸   XM_006239235
- Peptide Label: isoform X2
- UniProtKB: Q76LT8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000030008   ⟸   ENSRNOT00000031855
RefSeq Acc Id: ENSRNOP00000069188   ⟸   ENSRNOT00000077933
RefSeq Acc Id: XP_038966349   ⟸   XM_039110421
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000095844   ⟸   ENSRNOT00000112285
Protein Domains
DUSP   Ubiquitin-like   USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q76LT8-F1-model_v2 AlphaFold Q76LT8 1-1036 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694181
Promoter ID:EPDNEW_R4706
Type:initiation region
Name:Usp48_1
Description:ubiquitin specific peptidase 48
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05155,935,534 - 155,935,594EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735213 AgrOrtholog
BioCyc Gene G2FUF-39473 BioCyc
Ensembl Genes ENSRNOG00000013602 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000031855 ENTREZGENE
  ENSRNOT00000031855.6 UniProtKB/TrEMBL
  ENSRNOT00000077933.2 UniProtKB/TrEMBL
  ENSRNOT00000112285.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine proteinases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DUSP-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C19_DUSP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin_dom UniProtKB/Swiss-Prot
  Ubl_USP48 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP48 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362636 UniProtKB/Swiss-Prot
NCBI Gene 362636 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 48 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUSP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Usp48 PhenoGen
PROSITE DUSP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013602 RatGTEx
Superfamily-SCOP SSF143791 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JUQ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6B3E6_RAT UniProtKB/TrEMBL
  F1M9B3_RAT UniProtKB/TrEMBL
  Q76LT8 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Usp48  ubiquitin specific peptidase 48  LOC100911993  ubiquitin carboxyl-terminal hydrolase 48-like  Data merged from RGD:6489246 737654 PROVISIONAL
2012-07-05 LOC100911993  ubiquitin carboxyl-terminal hydrolase 48-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-07 Usp48  ubiquitin specific peptidase 48  Usp48  ubiquitin specific protease 48  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Usp48  ubiquitin specific protease 48  Usp31  ubiquitin specific protease 31  Symbol and Name updated 1299863 APPROVED