Gstk1 (glutathione S-transferase kappa 1) - Rat Genome Database

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Gene: Gstk1 (glutathione S-transferase kappa 1) Rattus norvegicus
Analyze
Symbol: Gstk1
Name: glutathione S-transferase kappa 1
RGD ID: 735188
Description: Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in epithelial cell differentiation and glutathione metabolic process. Located in mitochondrial matrix. Orthologous to human GSTK1 (glutathione S-transferase kappa 1); PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: glutathione S-transferase subunit 13; glutathione S-transferase, mitochondrial; GST 13-13; GST class-kappa; GST13-13; GSTK1-1; GSTkappa; rGSTK1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8472,085,532 - 72,089,934 (+)NCBIGRCr8
mRatBN7.2471,118,979 - 71,123,298 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl471,118,896 - 71,123,292 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx476,038,785 - 76,043,096 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0471,952,032 - 71,956,343 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0470,371,499 - 70,375,808 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0471,621,777 - 71,626,096 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl471,621,729 - 71,626,107 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04136,427,328 - 136,431,713 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4469,999,767 - 70,004,086 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1470,275,896 - 70,280,216 (+)NCBI
Celera466,050,514 - 66,054,833 (+)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstk1Ratosteoarthritis  ISOGSTK1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18784066
Gstk1RatProstatic Neoplasms  ISOGSTK1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17013881

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstk1Rat(+)-dexrazoxane multiple interactionsISOGstk1 (Mus musculus)6480464[Doxorubicin co-treated with Dexrazoxane] results in increased expression of GSTK1 mRNACTDPMID:26873546
Gstk1Rat(S)-nicotine decreases expressionISOGstk1 (Mus musculus)6480464Nicotine results in decreased expression of GSTK1 mRNACTDPMID:17997037
Gstk1Rat1,3-dinitrobenzene increases oxidationEXP 64804643-dinitrobenzene results in increased oxidation of GSTK1 proteinCTDPMID:25716674
Gstk1Rat1-naphthyl isothiocyanate multiple interactionsISOGSTK1 (Homo sapiens)6480464[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of GSTK1 mRNACTDPMID:27344345
Gstk1Rat17beta-estradiol decreases expressionISOGSTK1 (Homo sapiens)6480464Estradiol results in decreased expression of GSTK1 mRNACTDPMID:23019147
Gstk1Rat17beta-estradiol decreases expressionISOGstk1 (Mus musculus)6480464Estradiol results in decreased expression of GSTK1 mRNACTDPMID:39298647
Gstk1Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of GSTK1 mRNACTDPMID:32145629
Gstk1Rat1H-pyrazole decreases expressionISOGstk1 (Mus musculus)6480464pyrazole results in decreased expression of GSTK1 mRNACTDPMID:17945193
Gstk1Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOGstk1 (Mus musculus)64804642 more ...CTDPMID:30294300
Gstk1Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOGSTK1 (Homo sapiens)64804642 more ...CTDPMID:31675489
Gstk1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOGstk1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of GSTK1 mRNACTDPMID:19770486
Gstk1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of GSTK1 mRNACTDPMID:18796159 more ...
Gstk1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOGstk1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of GSTK1 mRNACTDPMID:21570461
Gstk1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOGstk1 (Mus musculus)6480464Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to GSTK1 promoter]CTDPMID:19654925
Gstk1Rat2,4,6-tribromophenol decreases expressionISOGSTK1 (Homo sapiens)64804642 more ...CTDPMID:31675489
Gstk1Rat3-methylcholanthrene increases expressionEXP 6480464Methylcholanthrene results in increased expression of GSTK1 mRNACTDPMID:23273579
Gstk1Rat3H-1,2-dithiole-3-thione increases expressionEXP 64804641 and 2-dithiol-3-thione results in increased expression of GSTK1 mRNACTDPMID:19162173
Gstk1Rat4,4'-sulfonyldiphenol decreases expressionISOGstk1 (Mus musculus)6480464bisphenol S results in decreased expression of GSTK1 mRNACTDPMID:39298647
Gstk1Rat4,4'-sulfonyldiphenol increases expressionISOGSTK1 (Homo sapiens)6480464bisphenol S results in increased expression of GSTK1 proteinCTDPMID:34186270
Gstk1Rat4-nitrophenol decreases expressionISOGstk1 (Mus musculus)64804644-nitrophenol results in decreased expression of GSTK1 mRNACTDPMID:34673133

1 to 20 of 174 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstk1Ratcellular oxidant detoxification involved_inIEAGO:00046021600115GO_REF:0000108GOCGO_REF:0000108
Gstk1Ratepithelial cell differentiation involved_inISOGSTK1 (Homo sapiens)1624291 PMID:21492153RGDPMID:21492153
Gstk1Ratepithelial cell differentiation involved_inIEAUniProtKB:Q9Y2Q3 and ensembl:ENSP000003511811600115GO_REF:0000107EnsemblGO_REF:0000107
Gstk1Ratglutathione metabolic process involved_inIEAInterPro:IPR0440881600115GO_REF:0000002InterProGO_REF:0000002
Gstk1Ratglutathione metabolic process acts_upstream_of_or_withinIEAUniProtKB:Q9DCM2 and ensembl:ENSMUSP000000318971600115GO_REF:0000107EnsemblGO_REF:0000107
Gstk1Ratglutathione metabolic process acts_upstream_of_or_withinISOGstk1 (Mus musculus)1624291 PMID:12720545RGDPMID:12720545
Gstk1Ratglutathione metabolic process involved_inIBAMGI:1923513 and PANTHER:PTN0010160581600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstk1Ratcytoplasm located_inIEAARBA:ARBA000269711600115GO_REF:0000117UniProtGO_REF:0000117
Gstk1Ratintracellular membrane-bounded organelle located_inIEAARBA:ARBA000290851600115GO_REF:0000117UniProtGO_REF:0000117
Gstk1Ratmitochondrial matrix  TAS 1299650 RGD 
Gstk1Ratmitochondrial matrix located_inIEAUniProtKB-SubCell:SL-01701600115GO_REF:0000044UniProtGO_REF:0000044
Gstk1Ratmitochondrial matrix located_inIDA 1580664PMID:14561759HGNC-UCL 
Gstk1Ratmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
Gstk1Ratmitochondrion located_inIEAUniProtKB:Q9DCM2 and ensembl:ENSMUSP000000318971600115GO_REF:0000107EnsemblGO_REF:0000107
Gstk1Ratmitochondrion located_inISOGstk1 (Mus musculus)1624291 PMID:12720545 and PMID:15100242RGDPMID:12720545 and PMID:15100242
Gstk1Ratmitochondrion is_active_inIBAMGI:1923513 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gstk1Ratperoxisome located_inISOGSTK1 (Homo sapiens)1624291 PMID:14742434RGDPMID:14742434
Gstk1Ratperoxisome located_inIEAUniProtKB:Q6FII1 and ensembl:ENSP000003511811600115GO_REF:0000107EnsemblGO_REF:0000107
Gstk1Ratperoxisome is_active_inIBAPANTHER:PTN001016058 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gstk1Ratperoxisome located_inIEAUniProtKB:Q9Y2Q3 and ensembl:ENSP000003511811600115GO_REF:0000107EnsemblGO_REF:0000107
Gstk1Ratperoxisome located_inISOGSTK1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
1 to 14 of 14 rows

Molecular Function
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstk1Ratglutathione peroxidase activity enablesISOGSTK1 (Homo sapiens)1624291 PMID:14742434RGDPMID:14742434
Gstk1Ratglutathione peroxidase activity enablesIEAUniProtKB:Q9Y2Q3 and ensembl:ENSP000003511811600115GO_REF:0000107EnsemblGO_REF:0000107
Gstk1Ratglutathione peroxidase activity enablesIEAUniProtKB:Q9DCM2 and ensembl:ENSMUSP000000318971600115GO_REF:0000107EnsemblGO_REF:0000107
Gstk1Ratglutathione peroxidase activity enablesISOGstk1 (Mus musculus)1624291 PMID:12720545RGDPMID:12720545
Gstk1Ratglutathione peroxidase activity enablesIBAMGI:1923513 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gstk1Ratglutathione peroxidase activity enablesIEAInterPro:IPR0440881600115GO_REF:0000002InterProGO_REF:0000002
Gstk1Ratglutathione transferase activity enablesISOGSTK1 (Homo sapiens)1624291 PMID:14742434RGDPMID:14742434
Gstk1Ratglutathione transferase activity enablesIEAInterPro:IPR0440881600115GO_REF:0000002InterProGO_REF:0000002
Gstk1Ratglutathione transferase activity enablesIEAUniProtKB:Q9Y2Q3 and ensembl:ENSP000003511811600115GO_REF:0000107EnsemblGO_REF:0000107
Gstk1Ratglutathione transferase activity enablesIEAUniProtKB:Q9DCM2 and ensembl:ENSMUSP000000318971600115GO_REF:0000107EnsemblGO_REF:0000107
Gstk1Ratglutathione transferase activity enablesIBAMGI:1923513 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gstk1Ratglutathione transferase activity enablesISOGstk1 (Mus musculus)1624291 PMID:12720545RGDPMID:12720545
Gstk1Ratglutathione transferase activity enablesIEAEC:2.5.1.181600115GO_REF:0000003UniProtGO_REF:0000003
Gstk1Ratoxidoreductase activity enablesIEAInterPro:IPR0018531600115GO_REF:0000002InterProGO_REF:0000002
Gstk1Ratprotein binding enablesISOGSTK1 (Homo sapiens) and UniProtKB:Q9Y2Q3-21624291UniProtKB:Q7Z3Y8 and PMID:32296183RGDPMID:32296183
Gstk1Ratprotein binding enablesISOGstk1 (Mus musculus)1624291UniProtKB:Q60994 and PMID:19011089RGDPMID:19011089
Gstk1Ratprotein binding enablesISOGSTK1 (Homo sapiens)1624291UniProtKB:O95273 more ...RGDPMID:19011089 more ...
Gstk1Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
1 to 18 of 18 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstk1Ratglutathione conjugation pathway  ISS 1358120 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstk1Ratglutathione metabolic pathway  IEA 6907045 KEGGrno:00480
Gstk1Ratphase I biotransformation pathway via cytochrome P450  IEA 6907045 KEGGrno:00980
Gstk1Ratphase I biotransformation pathway via cytochrome P450  IEA 6907045 KEGGrno:00982

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Glutathione S-transferase class Kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue. Pemble SE, etal., Biochem J 1996 Nov 1;319 ( Pt 3):749-54.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Glutathione S-transferase: genetics and role in toxicology. Strange RC, etal., Toxicol Lett 2000 Mar 15;112-113:357-63.
PMID:1883325   PMID:12477932   PMID:12720545   PMID:12865426   PMID:14651853   PMID:14742434   PMID:18614015   PMID:19199708   PMID:19946888   PMID:20178365   PMID:21492153   PMID:23376485  



Gstk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8472,085,532 - 72,089,934 (+)NCBIGRCr8
mRatBN7.2471,118,979 - 71,123,298 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl471,118,896 - 71,123,292 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx476,038,785 - 76,043,096 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0471,952,032 - 71,956,343 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0470,371,499 - 70,375,808 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0471,621,777 - 71,626,096 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl471,621,729 - 71,626,107 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04136,427,328 - 136,431,713 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4469,999,767 - 70,004,086 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1470,275,896 - 70,280,216 (+)NCBI
Celera466,050,514 - 66,054,833 (+)NCBICelera
Cytogenetic Map4q24NCBI
GSTK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387143,263,441 - 143,269,115 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7143,244,093 - 143,270,854 (+)EnsemblGRCh38hg38GRCh38
GRCh377142,960,534 - 142,966,208 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367142,670,686 - 142,676,328 (+)NCBINCBI36Build 36hg18NCBI36
Celera7137,797,393 - 137,803,091 (+)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7137,297,887 - 137,303,587 (+)NCBIHuRef
CHM1_17142,897,388 - 142,903,108 (+)NCBICHM1_1
T2T-CHM13v2.07144,618,862 - 144,624,534 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27142,362,642 - 142,368,342 (+)NCBI
Gstk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39642,222,869 - 42,227,375 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl642,222,869 - 42,227,381 (+)EnsemblGRCm39 Ensembl
GRCm38642,245,935 - 42,250,441 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl642,245,935 - 42,250,447 (+)EnsemblGRCm38mm10GRCm38
MGSCv37642,195,934 - 42,200,440 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36642,175,542 - 42,180,048 (+)NCBIMGSCv36mm8
Celera642,190,122 - 42,194,626 (+)NCBICelera
Cytogenetic Map6B2.1NCBI
cM Map620.52NCBI
Gstk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955494383,341 - 387,630 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955494383,107 - 387,483 (-)NCBIChiLan1.0ChiLan1.0
GSTK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26180,116,341 - 180,122,050 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1732,126,607 - 32,136,166 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07135,258,184 - 135,267,254 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17147,749,461 - 147,755,158 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7147,749,461 - 147,755,158 (+)Ensemblpanpan1.1panPan2
GSTK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,411,678 - 6,416,135 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,400,563 - 7,405,021 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0166,265,390 - 6,269,847 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,265,390 - 6,269,842 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,212,775 - 6,217,230 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,064,698 - 6,069,155 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,140,101 - 6,144,565 (-)NCBIUU_Cfam_GSD_1.0
Gstk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511812,176,254 - 12,180,877 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936527722,083 - 728,824 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936527722,548 - 727,169 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GSTK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,992,647 - 6,999,068 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,992,623 - 6,999,068 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2187,234,405 - 7,239,989 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GSTK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121112,149,949 - 112,155,579 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21112,149,970 - 112,155,300 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660728,874,033 - 8,879,741 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gstk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480011,478,510 - 11,486,122 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480011,481,664 - 11,486,256 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Gstk1
3 total Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
4 136428885 136428886 G A snv IS-Tlk/Kyo (KyushuU) View more Information

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:33
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000022275
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 58 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711470578881294Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat

1 to 10 of 58 rows
RH128940  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2471,123,128 - 71,123,286 (+)MAPPERmRatBN7.2
Rnor_6.0471,625,927 - 71,626,084NCBIRnor6.0
Rnor_5.04136,431,543 - 136,431,700UniSTSRnor5.0
RGSC_v3.4470,003,917 - 70,004,074UniSTSRGSC3.4
Celera466,054,664 - 66,054,821UniSTS
RH 3.4 Map4434.82UniSTS
Cytogenetic Map4q23UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000022275   ⟹   ENSRNOP00000022275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl471,118,896 - 71,123,292 (+)Ensembl
Rnor_6.0 Ensembl471,621,729 - 71,626,107 (+)Ensembl
RefSeq Acc Id: NM_181371   ⟹   NP_852036
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8472,085,614 - 72,089,933 (+)NCBI
mRatBN7.2471,118,979 - 71,123,298 (+)NCBI
Rnor_6.0471,621,777 - 71,626,096 (+)NCBI
Rnor_5.04136,427,328 - 136,431,713 (+)NCBI
RGSC_v3.4469,999,767 - 70,004,086 (+)RGD
Celera466,050,514 - 66,054,833 (+)RGD
Sequence:
RefSeq Acc Id: XM_063285766   ⟹   XP_063141836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8472,085,532 - 72,089,934 (+)NCBI
Protein RefSeqs NP_852036 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141836 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB50831 (Get FASTA)   NCBI Sequence Viewer  
  ACI32117 (Get FASTA)   NCBI Sequence Viewer  
  EDM15501 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022275
  ENSRNOP00000022275.2
GenBank Protein P24473 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_852036   ⟸   NM_181371
- UniProtKB: O09034 (UniProtKB/Swiss-Prot),   P24473 (UniProtKB/Swiss-Prot),   B6DYQ0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022275   ⟸   ENSRNOT00000022275
RefSeq Acc Id: XP_063141836   ⟸   XM_063285766
- Peptide Label: isoform X1
DSBA-like thioredoxin

Name Modeler Protein Id AA Range Protein Structure
AF-P24473-F1-model_v2 AlphaFold P24473 1-226 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693007
Promoter ID:EPDNEW_R3530
Type:initiation region
Name:Gstk1_1
Description:glutathione S-transferase kappa 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0471,621,761 - 71,621,821EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-45097 BioCyc
Ensembl Genes ENSRNOG00000016484 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022275 ENTREZGENE
  ENSRNOT00000022275.5 UniProtKB/Swiss-Prot
Gene3D-CATH Glutaredoxin UniProtKB/Swiss-Prot
InterPro DSBA-like_thioredoxin_dom UniProtKB/Swiss-Prot
  GST_Kappa/NadH UniProtKB/Swiss-Prot
  GSTK UniProtKB/Swiss-Prot
  HCCAis_GSTk UniProtKB/Swiss-Prot
  Thioredoxin-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:297029 UniProtKB/Swiss-Prot
NCBI Gene 297029 ENTREZGENE
PANTHER GLUTATHIONE S-TRANSFERASE KAPPA UniProtKB/Swiss-Prot
  GLUTATHIONE S-TRANSFERASE KAPPA 1 UniProtKB/Swiss-Prot
Pfam DSBA UniProtKB/Swiss-Prot
PhenoGen Gstk1 PhenoGen
PIRSF HCCAis_GSTk UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016484 RatGTEx
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot
UniProt B6DYQ0 ENTREZGENE, UniProtKB/TrEMBL
  GSTK1_RAT UniProtKB/Swiss-Prot
  O09034 ENTREZGENE
  P24473 ENTREZGENE
UniProt Secondary O09034 UniProtKB/Swiss-Prot
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-07-08 Gstk1  glutathione S-transferase kappa 1  GST13-13  glutathione S-transferase, mitochondrial  Symbol and Name updated 1299863 APPROVED