Eif3h (eukaryotic translation initiation factor 3, subunit H) - Rat Genome Database

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Gene: Eif3h (eukaryotic translation initiation factor 3, subunit H) Rattus norvegicus
Analyze
Symbol: Eif3h
Name: eukaryotic translation initiation factor 3, subunit H
RGD ID: 735178
Description: Predicted to enable metal-dependent deubiquitinase activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process and translational initiation. Predicted to be part of eukaryotic 43S preinitiation complex and eukaryotic translation initiation factor 3 complex, eIF3m. Human ortholog(s) of this gene implicated in breast cancer; prostate cancer; and prostate carcinoma. Orthologous to human EIF3H (eukaryotic translation initiation factor 3 subunit H); PARTICIPATES IN translation initiation pathway; measles pathway; RNA transport pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: eIF-3 gamma; eIF-3-gamma; eIF3 p40 subunit; Eif3s3; eukaryotic translation initiation factor 3 subunit 3; eukaryotic translation initiation factor 3 subunit H; eukaryotic translation initiation factor 3, subunit 3 gamma; eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa; LOC108348062; MGC72941
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8784,980,891 - 85,064,284 (-)NCBIGRCr8
mRatBN7.2783,091,037 - 83,174,451 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl783,091,039 - 83,174,451 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx784,986,868 - 85,070,126 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0787,188,085 - 87,271,343 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0787,015,192 - 87,098,341 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0610,151,732 - 10,236,677 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl610,151,729 - 10,236,695 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl610,151,729 - 10,236,695 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl6108,745,895 - 108,756,130 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06116,798,908 - 116,803,475 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.06116,806,338 - 116,856,511 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4788,069,668 - 88,154,285 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1788,090,397 - 88,175,015 (-)NCBI
Celera779,969,394 - 80,052,871 (-)NCBICelera
Cytogenetic Map7q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structure of initiation factor eIF-3 from rat liver. Hydrodynamic and electron microscopic investigations. Behlke J, etal., Eur J Biochem. 1986 Jun 16;157(3):523-30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. The scanning mechanism of eukaryotic translation initiation. Hinnebusch AG Annu Rev Biochem. 2014;83:779-812. doi: 10.1146/annurev-biochem-060713-035802. Epub 2014 Jan 29.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Amplification and overexpression of p40 subunit of eukaryotic translation initiation factor 3 in breast and prostate cancer. Nupponen NN, etal., Am J Pathol. 1999 Jun;154(6):1777-83.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Information Derived from GenBank Report RGD, Sept. 2003
12. Amplification of EIF3S3 gene is associated with advanced stage in prostate cancer. Saramaki O, etal., Am J Pathol. 2001 Dec;159(6):2089-94.
13. Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer. Savinainen KJ, etal., Br J Cancer. 2004 Mar 8;90(5):1041-6.
14. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:17322308   PMID:17581632   PMID:18599441   PMID:19056867   PMID:19946888   PMID:22658674   PMID:24003236   PMID:25849773  


Genomics

Comparative Map Data
Eif3h
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8784,980,891 - 85,064,284 (-)NCBIGRCr8
mRatBN7.2783,091,037 - 83,174,451 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl783,091,039 - 83,174,451 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx784,986,868 - 85,070,126 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0787,188,085 - 87,271,343 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0787,015,192 - 87,098,341 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0610,151,732 - 10,236,677 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl610,151,729 - 10,236,695 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl610,151,729 - 10,236,695 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl6108,745,895 - 108,756,130 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06116,798,908 - 116,803,475 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.06116,806,338 - 116,856,511 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4788,069,668 - 88,154,285 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1788,090,397 - 88,175,015 (-)NCBI
Celera779,969,394 - 80,052,871 (-)NCBICelera
Cytogenetic Map7q31NCBI
EIF3H
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388116,642,130 - 116,766,374 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8116,642,130 - 116,766,925 (-)EnsemblGRCh38hg38GRCh38
GRCh378117,654,369 - 117,768,062 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368117,726,236 - 117,837,243 (-)NCBINCBI36Build 36hg18NCBI36
Build 348117,726,266 - 117,837,222NCBI
Celera8113,843,130 - 113,956,776 (-)NCBICelera
Cytogenetic Map8q23.3-q24.11NCBI
HuRef8112,983,503 - 113,094,395 (-)NCBIHuRef
CHM1_18117,697,603 - 117,808,219 (-)NCBICHM1_1
T2T-CHM13v2.08117,769,451 - 117,883,944 (-)NCBIT2T-CHM13v2.0
Eif3h
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391551,649,956 - 51,728,901 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1551,649,954 - 51,728,919 (-)EnsemblGRCm39 Ensembl
GRCm381551,786,563 - 51,865,461 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1551,786,558 - 51,865,523 (-)EnsemblGRCm38mm10GRCm38
MGSCv371551,618,109 - 51,697,007 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361551,616,637 - 51,695,535 (-)NCBIMGSCv36mm8
Celera1553,359,320 - 53,438,134 (-)NCBICelera
Cytogenetic Map15CNCBI
cM Map1519.42NCBI
Eif3h
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541722,754,395 - 22,846,618 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541722,757,781 - 22,846,349 (-)NCBIChiLan1.0ChiLan1.0
EIF3H
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27134,048,331 - 134,158,684 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18109,567,521 - 109,677,808 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08113,320,059 - 113,440,769 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18115,863,493 - 115,984,107 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8115,863,490 - 115,973,872 (-)Ensemblpanpan1.1panPan2
EIF3H
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11316,105,960 - 16,201,902 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1316,105,990 - 16,341,153 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1316,107,272 - 16,203,193 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01316,393,919 - 16,489,878 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1316,393,949 - 16,490,038 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11316,139,289 - 16,233,993 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01316,238,566 - 16,334,288 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01316,479,179 - 16,575,072 (-)NCBIUU_Cfam_GSD_1.0
Eif3h
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530322,083,049 - 22,180,007 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647029,509,151 - 29,606,124 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647029,509,154 - 29,606,124 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF3H
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl421,954,874 - 22,058,699 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1421,955,026 - 22,053,683 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2423,327,980 - 23,448,893 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF3H
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18111,283,184 - 111,390,835 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603928,934,660 - 29,042,760 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif3h
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476314,935,271 - 15,027,010 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476314,938,624 - 15,027,001 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eif3h
391 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:95
Interacting mature miRNAs:98
Transcripts:ENSRNOT00000005786
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
724537Niddm52Non-insulin dependent diabetes mellitus QTL 520.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)78022129993595843Rat
1641908Teswt1Testicular weight QTL 13.28testis mass (VT:1000644)both testes wet weight (CMO:0000175)78022129994811326Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat

Markers in Region
D7Rat86  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2783,153,392 - 83,153,512 (-)MAPPERmRatBN7.2
Rnor_6.0610,173,862 - 10,173,981NCBIRnor6.0
Rnor_6.06108,696,796 - 108,696,915NCBIRnor6.0
Rnor_5.06116,858,276 - 116,858,395UniSTSRnor5.0
Rnor_5.0620,168,871 - 20,168,990UniSTSRnor5.0
RGSC_v3.4788,132,195 - 88,132,315RGDRGSC3.4
RGSC_v3.4788,132,196 - 88,132,315UniSTSRGSC3.4
RGSC_v3.1788,152,926 - 88,153,045RGD
Celera780,031,740 - 80,031,859UniSTS
RH 3.4 Map7545.2UniSTS
RH 3.4 Map7545.2RGD
RH 2.0 Map7472.9RGD
SHRSP x BN Map750.08RGD
FHH x ACI Map740.04RGD
Cytogenetic Map7q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_198751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC060586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000005786   ⟹   ENSRNOP00000005786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl783,091,039 - 83,152,147 (-)Ensembl
Rnor_6.0 Ensembl610,151,729 - 10,236,695 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000061786   ⟹   ENSRNOP00000058501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl783,091,039 - 83,105,508 (-)Ensembl
Rnor_6.0 Ensembl6108,745,895 - 108,756,130 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094377   ⟹   ENSRNOP00000080205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl783,092,893 - 83,174,451 (-)Ensembl
RefSeq Acc Id: NM_198751   ⟹   NP_942046
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8784,980,891 - 85,064,284 (-)NCBI
mRatBN7.2783,091,037 - 83,174,451 (-)NCBI
Rnor_6.0610,151,732 - 10,236,677 (+)NCBI
Rnor_5.06116,806,338 - 116,856,511 (-)NCBI
Rnor_5.06116,798,908 - 116,803,475 (-)NCBI
RGSC_v3.4788,069,668 - 88,154,285 (-)RGD
Celera779,969,394 - 80,052,871 (-)RGD
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_942046   ⟸   NM_198751
- UniProtKB: Q6P9U8 (UniProtKB/Swiss-Prot),   A0A8I5ZP79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005786   ⟸   ENSRNOT00000005786
RefSeq Acc Id: ENSRNOP00000058501   ⟸   ENSRNOT00000061786
RefSeq Acc Id: ENSRNOP00000080205   ⟸   ENSRNOT00000094377
Protein Domains
JAB1/MPN/MOV34 metalloenzyme   MPN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZL77-F1-model_v2 AlphaFold D3ZL77 1-256 view protein structure
AF-Q6P9U8-F1-model_v2 AlphaFold Q6P9U8 1-352 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694394
Promoter ID:EPDNEW_R4909
Type:multiple initiation site
Name:LOC108348062_1
Description:eukaryotic translation initiation factor 3 subunit H
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0610,151,731 - 10,151,791EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735178 AgrOrtholog
BioCyc Gene G2FUF-33430 BioCyc
Ensembl Genes ENSRNOG00000004252 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000040153 Ensembl
  ENSRNOG00055021689 UniProtKB/Swiss-Prot
  ENSRNOG00060003443 UniProtKB/Swiss-Prot
  ENSRNOG00065014836 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005786 ENTREZGENE
  ENSRNOT00000005786.7 UniProtKB/TrEMBL
  ENSRNOT00000061786.5 UniProtKB/TrEMBL
  ENSRNOT00000094377.1 UniProtKB/TrEMBL
  ENSRNOT00055037161 UniProtKB/Swiss-Prot
  ENSRNOT00060005682 UniProtKB/Swiss-Prot
  ENSRNOT00065024567 UniProtKB/Swiss-Prot
Gene3D-CATH Cytidine Deaminase, domain 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6918037 IMAGE-MGC_LOAD
InterPro eIF3h UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  eIF3h_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  JAMM/MPN+_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MPN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:299899 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72941 IMAGE-MGC_LOAD
NCBI Gene 299899 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10410:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam eIF3h_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  JAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eif3h PhenoGen
PROSITE MPN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004252 RatGTEx
  ENSRNOG00000040153 RatGTEx
  ENSRNOG00055021689 RatGTEx
  ENSRNOG00060003443 RatGTEx
  ENSRNOG00065014836 RatGTEx
SMART JAB_MPN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZP79 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UHR1_RAT UniProtKB/TrEMBL
  D3ZL77_RAT UniProtKB/TrEMBL
  EIF3H_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Eif3h  eukaryotic translation initiation factor 3, subunit H  LOC108348062  eukaryotic translation initiation factor 3 subunit H  Data merged from RGD:11498408 737654 PROVISIONAL
2016-08-02 LOC108348062  eukaryotic translation initiation factor 3 subunit H      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-04     Eif3h  eukaryotic translation initiation factor 3, subunit H  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Eif3h  eukaryotic translation initiation factor 3, subunit H  Eif3s3  eukaryotic translation initiation factor 3, subunit 3 gamma  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2005-07-08 Eif3s3  eukaryotic translation initiation factor 3, subunit 3 (gamma)    eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa  Name updated 1299863 APPROVED