Ugdh (UDP-glucose 6-dehydrogenase) - Rat Genome Database

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Gene: Ugdh (UDP-glucose 6-dehydrogenase) Rattus norvegicus
Analyze
Symbol: Ugdh
Name: UDP-glucose 6-dehydrogenase
RGD ID: 621879
Description: Enables UDP-glucose 6-dehydrogenase activity. Predicted to be involved in several processes, including UDP-glucuronate biosynthetic process; protein hexamerization; and proteoglycan biosynthetic process. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 84. Orthologous to human UGDH (UDP-glucose 6-dehydrogenase); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; galactokinase deficiency pathway; GALE deficiency pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: UDP-Glc dehydrogenase; UDP-GlcDH; UDP-glucose dehydrogeanse; UDP-glucose dehydrogenase; UDPGDH
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,202,480 - 43,226,002 (+)NCBIGRCr8
mRatBN7.21442,848,704 - 42,872,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,848,854 - 42,872,354 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1443,202,670 - 43,226,148 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01444,502,588 - 44,526,066 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01442,982,708 - 43,006,181 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01444,479,614 - 44,502,845 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,479,614 - 44,502,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,299,226 - 44,322,226 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,542,781 - 45,570,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11445,545,171 - 45,573,352 (+)NCBI
Celera1441,999,555 - 42,023,022 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UgdhRatdevelopmental and epileptic encephalopathy 84  ISOUGDH (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
UgdhRatgeneralized epilepsy  ISOUGDH (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 more ...
UgdhRatgenetic disease  ISOUGDH (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVar 
UgdhRatHyperglycinemia, Lactic Acidosis, and Seizures  ISOUGDH (Homo sapiens)8554872ClinVar more ...ClinVarPMID:28492532
UgdhRatWest syndrome  ISOUGDH (Homo sapiens)8554872ClinVar Annotator: match by term: West syndromeClinVarPMID:25741868 and PMID:32001716
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UgdhRatLiver Neoplasms  ISOUGDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17114358
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UgdhRatdevelopmental and epileptic encephalopathy 84  ISOUGDH (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UgdhRat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of UGDH mRNA]CTDPMID:31150632
UgdhRat(-)-epigallocatechin 3-gallate increases expressionISOUGDH (Homo sapiens)6480464epigallocatechin gallate results in increased expression of UGDH mRNACTDPMID:16084531
UgdhRat(1->4)-beta-D-glucan multiple interactionsISOUgdh (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of UGDH mRNACTDPMID:36331819
UgdhRat1,2-dimethylhydrazine decreases expressionISOUgdh (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of UGDH mRNACTDPMID:22206623
UgdhRat1,2-dimethylhydrazine multiple interactionsISOUgdh (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of UGDH mRNACTDPMID:22206623
UgdhRat1-benzofuran affects expressionISOUgdh (Mus musculus)6480464benzofuran affects the expression of UGDH mRNACTDPMID:17114358
UgdhRat17alpha-ethynylestradiol increases expressionISOUgdh (Mus musculus)6480464Ethinyl Estradiol results in increased expression of UGDH mRNACTDPMID:17942748
UgdhRat17beta-estradiol multiple interactionsISOUGDH (Homo sapiens)6480464[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of UGDH mRNA and [Estradiol co-treated with TGFB1 protein] results in increased expression of UGDH mRNACTDPMID:19619570 and PMID:30165855
UgdhRat17beta-estradiol increases expressionISOUgdh (Mus musculus)6480464Estradiol results in increased expression of UGDH mRNACTDPMID:39298647
UgdhRat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of UGDH mRNACTDPMID:32145629
UgdhRat17beta-estradiol increases expressionISOUGDH (Homo sapiens)6480464Estradiol results in increased expression of UGDH mRNACTDPMID:19619570 and PMID:21185374
UgdhRat17beta-hydroxy-5alpha-androstan-3-one increases expressionISOUGDH (Homo sapiens)6480464Dihydrotestosterone results in increased expression of UGDH mRNACTDPMID:29581250
UgdhRat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOUgdh (Mus musculus)6480464[2 more ...CTDPMID:23457121
UgdhRat2,2',4,4',5,5'-hexachlorobiphenyl increases expressionISOUgdh (Mus musculus)64804642 more ...CTDPMID:20005886 and PMID:21851831
UgdhRat2,2',4,4'-Tetrabromodiphenyl ether multiple interactionsISOUgdh (Mus musculus)6480464[Flame Retardants results in increased abundance of 2 more ...CTDPMID:38995820
UgdhRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOUGDH (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of UGDH mRNACTDPMID:19619570
UgdhRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of UGDH mRNACTDPMID:33387578
UgdhRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of UGDH mRNACTDPMID:34747641
UgdhRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOUgdh (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of UGDH mRNACTDPMID:15328365 more ...
UgdhRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOUgdh (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of UGDH mRNACTDPMID:18343893 more ...

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Biological Process
1 to 20 of 23 rows

  
Object Symbol
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Qualifier
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Reference
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Source
Original Reference(s)
UgdhRatchondroitin sulfate proteoglycan biosynthetic process involved_inISOUgdh (Mus musculus)1624291 PMID:14505572RGDPMID:14505572
UgdhRatchondroitin sulfate proteoglycan biosynthetic process involved_inISSUniProtKB:O704751600115GO_REF:0000024UniProtGO_REF:0000024
UgdhRatchondroitin sulfate proteoglycan biosynthetic process involved_inIEAUniProtKB:O70475 and ensembl:ENSMUSP000000311031600115GO_REF:0000107EnsemblGO_REF:0000107
UgdhRatgastrulation with mouth forming second involved_inISOUgdh (Mus musculus)1624291 PMID:14505572RGDPMID:14505572
UgdhRatgastrulation with mouth forming second acts_upstream_of_or_withinIEAUniProtKB:O70475 and ensembl:ENSMUSP000000311031600115GO_REF:0000107EnsemblGO_REF:0000107
UgdhRatgastrulation with mouth forming second acts_upstream_of_or_withinISOUgdh (Mus musculus)1624291MGI:2678264 PMID:15755804RGDPMID:15755804
UgdhRatgastrulation with mouth forming second involved_inISSUniProtKB:O704751600115GO_REF:0000024UniProtGO_REF:0000024
UgdhRatglycosaminoglycan biosynthetic process involved_inIBAFB:FBgn0261445 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
UgdhRatheparan sulfate proteoglycan biosynthetic process involved_inIEAUniProtKB:O70475 and ensembl:ENSMUSP000000311031600115GO_REF:0000107EnsemblGO_REF:0000107
UgdhRatheparan sulfate proteoglycan biosynthetic process involved_inISOUgdh (Mus musculus)1624291 PMID:14505572RGDPMID:14505572
UgdhRatheparan sulfate proteoglycan biosynthetic process involved_inISSUniProtKB:O704751600115GO_REF:0000024UniProtGO_REF:0000024
UgdhRatneuron development involved_inISSUniProtKB:O607011600115GO_REF:0000024UniProtGO_REF:0000024
UgdhRatneuron development involved_inIEAUniProtKB:O60701 and ensembl:ENSP000003195011600115GO_REF:0000107EnsemblGO_REF:0000107
UgdhRatneuron development involved_inISOUGDH (Homo sapiens)1624291 PMID:32001716RGDPMID:32001716
UgdhRatprotein hexamerization involved_inISSUniProtKB:O607011600115GO_REF:0000024UniProtGO_REF:0000024
UgdhRatprotein hexamerization involved_inIEAUniProtKB:O60701 and ensembl:ENSP000003195011600115GO_REF:0000107EnsemblGO_REF:0000107
UgdhRatprotein hexamerization involved_inISOUGDH (Homo sapiens)1624291 PMID:27966912RGDPMID:27966912
UgdhRatUDP-glucuronate biosynthetic process involved_inISSUniProtKB:O607011600115GO_REF:0000024UniProtGO_REF:0000024
UgdhRatUDP-glucuronate biosynthetic process involved_inIEAUniProtKB:O70475 and ensembl:ENSMUSP000000311031600115GO_REF:0000107EnsemblGO_REF:0000107
UgdhRatUDP-glucuronate biosynthetic process involved_inIEAUniProtKB:O60701 and ensembl:ENSP000003195011600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component

  
Object Symbol
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Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
UgdhRatnucleoplasm located_inISOUGDH (Homo sapiens) more ...1624291 RGDGO_REF:0000052
UgdhRatnucleoplasm located_inIEAUniProtKB:O60701 and ensembl:ENSP000003195011600115GO_REF:0000107EnsemblGO_REF:0000107
UgdhRatnucleus is_active_inIBAPANTHER:PTN000146693 and UniProtKB:O607011600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 15 of 15 rows

  
Object Symbol
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Term
Qualifier
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Reference
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Source
Original Reference(s)
UgdhRatcatalytic activity enablesIEAUniProtKB-KW:KW-00211600115GO_REF:0000043UniProtGO_REF:0000043
UgdhRatidentical protein binding enablesISOUGDH (Homo sapiens)1624291UniProtKB:O60701 more ...RGDPMID:25416956 and PMID:32001716
UgdhRatidentical protein binding enablesIEAUniProtKB:O60701 and ensembl:ENSP000003195011600115GO_REF:0000107EnsemblGO_REF:0000107
UgdhRatNAD binding enablesIEAInterPro:IPR001732 more ...1600115GO_REF:0000002InterProGO_REF:0000002
UgdhRatoxidoreductase activity enablesIEAUniProtKB-KW:KW-05601600115GO_REF:0000043UniProtGO_REF:0000043
UgdhRatoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor enablesIEAInterPro:IPR001732 more ...1600115GO_REF:0000002InterProGO_REF:0000002
UgdhRatUDP-glucose 6-dehydrogenase activity enablesIEAEC:1.1.1.221600115GO_REF:0000003UniProtGO_REF:0000003
UgdhRatUDP-glucose 6-dehydrogenase activity  IDA 1304516 RGD 
UgdhRatUDP-glucose 6-dehydrogenase activity enablesIEAUniProtKB:O70475 and ensembl:ENSMUSP000000311031600115GO_REF:0000107EnsemblGO_REF:0000107
UgdhRatUDP-glucose 6-dehydrogenase activity enablesIEARHEA:235961600115GO_REF:0000116RHEAGO_REF:0000116
UgdhRatUDP-glucose 6-dehydrogenase activity enablesIEAInterPro:IPR0283561600115GO_REF:0000002InterProGO_REF:0000002
UgdhRatUDP-glucose 6-dehydrogenase activity enablesIEAARBA:ARBA000269261600115GO_REF:0000117UniProtGO_REF:0000117
UgdhRatUDP-glucose 6-dehydrogenase activity enablesIEAUniProtKB:O60701 and ensembl:ENSP000003195011600115GO_REF:0000107EnsemblGO_REF:0000107
UgdhRatUDP-glucose 6-dehydrogenase activity enablesISOUGDH (Homo sapiens)1624291 PMID:27966912RGDPMID:27966912
UgdhRatUDP-glucose 6-dehydrogenase activity enablesISOUgdh (Mus musculus)1624291 PMID:32768525 and PMID:9737970RGDPMID:32768525 and PMID:9737970
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Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
UgdhRatamino sugar metabolic pathway  IEA 6907045 KEGGrno:00520
UgdhRatascorbate and aldarate metabolic pathway  IEA 6907045 KEGGrno:00053
UgdhRatnucleotide sugar metabolic pathway  IEA 6907045 KEGGrno:00520
UgdhRatpentose and glucuronate interconversion pathway  IEA 6907045 KEGGrno:00040
UgdhRatstarch and sucrose metabolic pathway  IEA 6907045 KEGGrno:00500

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Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Characterization of human UDP-glucose dehydrogenase. CYS-276 is required for the second of two successive oxidations. Sommer BJ, etal., J Biol Chem 2004 May 28;279(22):23590-6. Epub 2004 Mar 24.
12. Molecular cloning and characterization of the human and mouse UDP-glucose dehydrogenase genes. Spicer AP, etal., J Biol Chem 1998 Sep 25;273(39):25117-24.
13. Enhancement of UDP-glucuronyltransferase, UDP-glucose dehydrogenase, and glutathione S-transferase activities in rat liver by dietary administration of eugenol. Yokota H, etal., Biochem Pharmacol 1988 Mar 1;37(5):799-802.
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PMID:14505572   PMID:15755804   PMID:16396499   PMID:16641100   PMID:23533145   PMID:25416956   PMID:27966912   PMID:32001716  



Ugdh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,202,480 - 43,226,002 (+)NCBIGRCr8
mRatBN7.21442,848,704 - 42,872,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,848,854 - 42,872,354 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1443,202,670 - 43,226,148 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01444,502,588 - 44,526,066 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01442,982,708 - 43,006,181 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01444,479,614 - 44,502,845 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,479,614 - 44,502,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,299,226 - 44,322,226 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,542,781 - 45,570,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11445,545,171 - 45,573,352 (+)NCBI
Celera1441,999,555 - 42,023,022 (+)NCBICelera
Cytogenetic Map14p11NCBI
UGDH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38439,498,755 - 39,527,439 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl439,498,755 - 39,528,311 (-)EnsemblGRCh38hg38GRCh38
GRCh37439,500,375 - 39,529,059 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36439,176,770 - 39,205,606 (-)NCBINCBI36Build 36hg18NCBI36
Build 34439,322,945 - 39,351,539NCBI
Celera439,938,164 - 39,967,004 (-)NCBICelera
Cytogenetic Map4p14NCBI
HuRef438,825,375 - 38,854,230 (-)NCBIHuRef
CHM1_1439,499,802 - 39,528,655 (-)NCBICHM1_1
T2T-CHM13v2.0439,468,409 - 39,497,229 (-)NCBIT2T-CHM13v2.0
Ugdh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39565,570,550 - 65,593,185 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl565,570,564 - 65,593,292 (-)EnsemblGRCm39 Ensembl
GRCm38565,413,207 - 65,435,842 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl565,413,221 - 65,435,949 (-)EnsemblGRCm38mm10GRCm38
MGSCv37565,804,460 - 65,827,081 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36565,692,356 - 65,714,977 (-)NCBIMGSCv36mm8
Celera562,689,905 - 62,712,959 (-)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map533.67NCBI
Ugdh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554437,868,893 - 7,882,129 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554437,868,893 - 7,882,136 (+)NCBIChiLan1.0ChiLan1.0
UGDH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2339,688,142 - 39,716,993 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1439,880,751 - 39,909,008 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0433,827,532 - 33,856,204 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1439,679,915 - 39,708,215 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl439,681,300 - 39,708,215 (-)Ensemblpanpan1.1panPan2
UGDH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1372,935,532 - 72,964,151 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl372,839,920 - 72,963,208 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha375,481,824 - 75,511,112 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0373,708,348 - 73,737,653 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl373,553,586 - 73,737,645 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1372,974,965 - 73,004,279 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0373,121,242 - 73,150,553 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0373,507,747 - 73,537,066 (+)NCBIUU_Cfam_GSD_1.0
Ugdh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528539,179,915 - 39,207,994 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364827,089,621 - 7,118,284 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364827,090,241 - 7,118,315 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UGDH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl830,725,288 - 30,759,326 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1830,725,281 - 30,759,359 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2832,340,313 - 32,374,310 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UGDH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12710,781,324 - 10,810,595 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2710,781,502 - 10,810,817 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604757,174,192 - 57,202,679 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ugdh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248704,782,252 - 4,799,703 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248704,768,307 - 4,801,333 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ugdh
73 total Variants

Predicted Target Of
Summary Value
Count of predictions:501
Count of miRNA genes:247
Interacting mature miRNAs:296
Transcripts:ENSRNOT00000003691
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 17 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142216796767167967Rat

1 to 10 of 17 rows
D14Got48  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21442,854,995 - 42,855,275 (+)MAPPERmRatBN7.2
Rnor_6.01444,485,742 - 44,486,023NCBIRnor6.0
Rnor_5.01444,305,152 - 44,305,433UniSTSRnor5.0
RGSC_v3.41445,549,232 - 45,549,514RGDRGSC3.4
RGSC_v3.41445,549,233 - 45,549,514UniSTSRGSC3.4
RGSC_v3.11445,551,623 - 45,551,905RGD
Celera1442,005,664 - 42,005,946UniSTS
Cytogenetic Map14p11UniSTS
RH134455  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21442,871,941 - 42,872,157 (+)MAPPERmRatBN7.2
Rnor_6.01444,502,436 - 44,502,651NCBIRnor6.0
Rnor_5.01444,321,817 - 44,322,032UniSTSRnor5.0
RGSC_v3.41445,570,552 - 45,570,767UniSTSRGSC3.4
Celera1442,022,613 - 42,022,828UniSTS
Cytogenetic Map14p11UniSTS
RH143560  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21442,848,781 - 42,848,924 (+)MAPPERmRatBN7.2
Rnor_6.01444,479,540 - 44,479,682NCBIRnor6.0
Rnor_5.01444,299,152 - 44,299,294UniSTSRnor5.0
RGSC_v3.41445,542,707 - 45,542,849UniSTSRGSC3.4
Celera1441,999,481 - 41,999,623UniSTS
Cytogenetic Map14p11UniSTS
BF403257  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21442,849,132 - 42,849,288 (+)MAPPERmRatBN7.2
Rnor_6.01444,479,891 - 44,480,046NCBIRnor6.0
Rnor_5.01444,299,503 - 44,299,658UniSTSRnor5.0
RGSC_v3.41445,543,058 - 45,543,213UniSTSRGSC3.4
Celera1441,999,832 - 41,999,987UniSTS
Cytogenetic Map14p11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000003691   ⟹   ENSRNOP00000003691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1442,848,854 - 42,872,354 (+)Ensembl
Rnor_6.0 Ensembl1444,479,614 - 44,502,845 (+)Ensembl
RefSeq Acc Id: NM_031325   ⟹   NP_112615
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,202,518 - 43,226,002 (+)NCBI
mRatBN7.21442,848,856 - 42,872,351 (+)NCBI
Rnor_6.01444,479,614 - 44,502,845 (+)NCBI
Rnor_5.01444,299,226 - 44,322,226 (+)NCBI
RGSC_v3.41445,542,781 - 45,570,961 (+)RGD
Celera1441,999,555 - 42,023,022 (+)RGD
Sequence:
RefSeq Acc Id: XR_005493021
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,202,480 - 43,221,026 (+)NCBI
mRatBN7.21442,848,704 - 42,867,375 (+)NCBI
Protein RefSeqs NP_112615 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA28215 (Get FASTA)   NCBI Sequence Viewer  
  EDL90061 (Get FASTA)   NCBI Sequence Viewer  
  EDL90062 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000003691
GenBank Protein O70199 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_112615   ⟸   NM_031325
- UniProtKB: O70199 (UniProtKB/Swiss-Prot),   A6JDD9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003691   ⟸   ENSRNOT00000003691
Name Modeler Protein Id AA Range Protein Structure
AF-O70199-F1-model_v2 AlphaFold O70199 1-493 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699314
Promoter ID:EPDNEW_R9839
Type:multiple initiation site
Name:Ugdh_1
Description:UDP-glucose 6-dehydrogenase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01444,479,615 - 44,479,675EPDNEW


1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-15746 BioCyc
BioCyc Pathway PWY-7346 [UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)] BioCyc
BioCyc Pathway Image PWY-7346 BioCyc
Ensembl Genes ENSRNOG00000002643 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000003691 ENTREZGENE
Gene3D-CATH Cytochrome c1, transmembrane anchor, C-terminal UniProtKB/Swiss-Prot
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot
InterPro 6-PGluconate_DH-like_C_sf UniProtKB/Swiss-Prot
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
  UDP-Glc/GDP-Man UniProtKB/Swiss-Prot
  UDP-Glc/GDP-Man_DH_C UniProtKB/Swiss-Prot
  UDP-Glc/GDP-Man_DH_C_sf UniProtKB/Swiss-Prot
  UDP-Glc/GDP-Man_DH_dimer UniProtKB/Swiss-Prot
  UDP-Glc/GDP-Man_DH_N UniProtKB/Swiss-Prot
  UDPglc_DH_euk UniProtKB/Swiss-Prot
KEGG Report rno:83472 UniProtKB/Swiss-Prot
NCBI Gene 83472 ENTREZGENE
PANTHER PTHR11374 UniProtKB/Swiss-Prot
  UDP-GLUCOSE 6-DEHYDROGENASE UniProtKB/Swiss-Prot
Pfam UDPG_MGDP_dh UniProtKB/Swiss-Prot
  UDPG_MGDP_dh_C UniProtKB/Swiss-Prot
  UDPG_MGDP_dh_N UniProtKB/Swiss-Prot
PhenoGen Ugdh PhenoGen
PIRSF UDPglc_DH_euk UniProtKB/Swiss-Prot
  UDPglc_GDPman_dh UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002643 RatGTEx
SMART UDPG_MGDP_dh_C UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48179 UniProtKB/Swiss-Prot
  SSF51735 UniProtKB/Swiss-Prot
  SSF52413 UniProtKB/Swiss-Prot
UniProt A6JDD9 ENTREZGENE, UniProtKB/TrEMBL
  A6JDE0_RAT UniProtKB/TrEMBL
  G3V6C4_RAT UniProtKB/TrEMBL
  O70199 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Ugdh  UDP-glucose 6-dehydrogenase  Ugdh  UDP-glucose dehydrogenase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Ugdh  UDP-glucose dehydrogenase    UDP-glucose dehydrogeanse  Name updated 1299863 APPROVED
2002-08-07 Ugdh  UDP-glucose dehydrogeanse      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference