Smarca4 (SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4) - Rat Genome Database

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Gene: Smarca4 (SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4) Rattus norvegicus
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Symbol: Smarca4
Name: SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 (Ensembl:SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4)
RGD ID: 621728
Description: Enables chromatin binding activity. Involved in negative regulation of DNA-templated transcription; nucleosome disassembly; and spermatid development. Part of SWI/SNF complex. Used to study cocaine dependence. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 4; hepatocellular carcinoma; lung non-small cell carcinoma; and rhabdoid tumor predisposition syndrome 2. Orthologous to human SMARCA4 (SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4); PARTICIPATES IN altered SWI/SNF family mediated chromatin remodeling pathway; cortisol signaling pathway; histone modification pathway; INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP-dependent helicase SMARCA4; BAF190A; brg-1; BRG1-associated factor 190A; protein brahma homolog 1; SNF2-beta; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; transcription activator BRG1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8828,438,370 - 28,535,071 (+)NCBIGRCr8
mRatBN7.2820,167,717 - 20,258,975 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl820,167,717 - 20,258,975 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx824,200,412 - 24,292,032 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0822,495,960 - 22,587,578 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0820,397,343 - 20,488,586 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0822,648,323 - 22,739,468 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,648,323 - 22,739,468 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,702,277 - 22,793,519 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4820,720,915 - 20,812,157 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1820,787,909 - 20,796,297 (+)NCBI
Celera821,558,796 - 21,650,002 (+)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Original Reference(s)
Smarca4Ratcocaine dependence amelioratesIMP 597830063 RGD 
Smarca4RatExperimental Diabetes Mellitus treatmentIEP 9586347 RGD 
Smarca4Rathepatocellular carcinoma  ISOSMARCA4 (Homo sapiens)127285650DNA:SNPs: :rs11879293 and rs2072382 (human)RGD 
Smarca4RatLeft Ventricular Hypertrophy  IEP 9586349associated with Hypertension and protein:increased expression:heart left ventricleRGD 
Smarca4Ratlung non-small cell carcinoma  ISOSMARCA4 (Homo sapiens)2302526 RGD 
Smarca4Ratpancreatic cancer  ISOSMARCA4 (Homo sapiens)8694154 RGD 
Smarca4Ratprostate cancer no_associationISOSMARCA4 (Homo sapiens)2302528human gene: absence of somatic mutations in the samples usedRGD 
Smarca4Ratprostate cancer disease_progressionISOSMARCA4 (Homo sapiens)9068941 RGDPMID:17075831 and REF_RGD_ID:2302527
Smarca4RatProstatic Neoplasms  ISOSMARCA4 (Homo sapiens)2302527 RGD 
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Smarca4Ratalpha-mannosidosis  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Deficiency of alpha-mannosidaseClinVarPMID:28492532
Smarca4Ratatrial heart septal defect  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Atrial septal defectClinVarPMID:25741868 and PMID:28492532
Smarca4Ratautistic disorder  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Autistic behaviorClinVar 
Smarca4Ratbilateral breast cancer  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: bilateral breast cancerClinVarPMID:26467025 more ...
Smarca4Ratbreast cancer  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Malignant tumor of breastClinVarPMID:25741868 and PMID:28492532
Smarca4Ratcerebral palsy  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Cerebral palsyClinVarPMID:28492532 and PMID:34813034
Smarca4RatCharcot-Marie-Tooth disease dominant intermediate B  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease dominant intermediate BClinVarPMID:28492532
Smarca4Ratcleft palate  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Cleft palateClinVarPMID:22426308 more ...
Smarca4RatCoffin-Siris syndrome  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Coffin-Siris syndromeClinVarPMID:15756273 more ...
Smarca4RatCoffin-Siris syndrome 1  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Coffin-Siris syndrome 1ClinVarPMID:25741868
Smarca4RatCoffin-Siris syndrome 4  ISOSMARCA4 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10601012 more ...
Smarca4RatDevelopmental Disabilities  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25741868 and PMID:28492532
Smarca4Ratepilepsy  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: SeizureClinVarPMID:25741868 more ...
Smarca4Ratepisodic ataxia type 2  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Episodic ataxia type 2ClinVarPMID:28492532
Smarca4RatFacial Asymmetry  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Facial asymmetryClinVarPMID:25741868
Smarca4Ratfamilial hypercholesterolemia  ISOSMARCA4 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16250003 more ...
Smarca4Ratgenetic disease  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:10601012 more ...
Smarca4Ratglutaric acidemia I  ISOSMARCA4 (Homo sapiens)8554872ClinVar Annotator: match by term: Glutaric aciduria and type 1ClinVarPMID:28492532
Smarca4RatHereditary Neoplastic Syndromes  ISOSMARCA4 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15756273 more ...
Smarca4RatHereditary Neoplastic Syndromes  ISOSMARCA4 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15756273 more ...
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Smarca4Ratamyotrophic lateral sclerosis  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28973294
Smarca4RatBurkitt lymphoma  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23143597
Smarca4RatCocaine-Related Disorders  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27422367
Smarca4RatCoffin-Siris syndrome  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22426308
Smarca4Ratlung small cell carcinoma  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26343384
Smarca4RatOvarian Neoplasms  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:24658001 more ...
Smarca4Ratrhabdoid tumor predisposition syndrome 2  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Smarca4Ratsarcoma  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26343384
Smarca4RatSezary's disease  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26551667
Smarca4Ratsmall cell carcinoma  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:24658001 more ...
Smarca4RatT-cell acute lymphoblastic leukemia  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28671688
Smarca4RatThoracic Neoplasms  ISOSMARCA4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26343384
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Smarca4Ratbreast cancer  ISSSmarca4 (Mus musculus)13592920OMIM:114480MouseDO 
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Smarca4RatCoffin-Siris syndrome 4  ISOSMARCA4 (Homo sapiens)7240710 OMIM 
Smarca4Ratrhabdoid tumor predisposition syndrome 2  ISOSMARCA4 (Homo sapiens)7240710 OMIM 

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Smarca4Rat1,2-dichloroethane increases expressionISOSmarca4 (Mus musculus)6480464ethylene dichloride results in increased expression of SMARCA4 mRNACTDPMID:28960355
Smarca4Rat1,2-dimethylhydrazine increases expressionISOSmarca4 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of SMARCA4 mRNACTDPMID:22206623
Smarca4Rat1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine decreases expressionEXP 6480464chlorcyclizine results in decreased expression of SMARCA4 mRNACTDPMID:21058326
Smarca4Rat17alpha-ethynylestradiol multiple interactionsISOSmarca4 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SMARCA4 mRNACTDPMID:17942748
Smarca4Rat17alpha-ethynylestradiol increases expressionISOSmarca4 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of SMARCA4 mRNACTDPMID:17942748
Smarca4Rat17beta-estradiol decreases expressionISOSMARCA4 (Homo sapiens)6480464Estradiol results in decreased expression of SMARCA4 mRNACTDPMID:16705744 and PMID:19167446
Smarca4Rat17beta-hydroxy-5alpha-androstan-3-one multiple interactionsISOSMARCA4 (Homo sapiens)6480464[Dihydrotestosterone co-treated with bicalutamide] promotes the reaction [AR protein binds to SMARCA4 protein]CTDPMID:18487222
Smarca4Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOSMARCA4 (Homo sapiens)6480464SMARCA4 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] more ...CTDPMID:18842620
Smarca4Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of SMARCA4 mRNACTDPMID:33387578
Smarca4Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOSmarca4 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of SMARCA4 mRNACTDPMID:21570461
Smarca4Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of SMARCA4 mRNACTDPMID:18796159
Smarca4Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOSmarca4 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SMARCA4 mRNACTDPMID:17942748
Smarca4Rat3,4-methylenedioxymethamphetamine increases expressionISOSmarca4 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of SMARCA4 mRNACTDPMID:20188158
Smarca4Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of SMARCA4 proteinCTDPMID:34915118
Smarca4Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of SMARCA4 mRNACTDPMID:31881176
Smarca4Ratacrolein multiple interactionsISOSMARCA4 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SMARCA4 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of SMARCA4 mRNACTDPMID:32699268
Smarca4Rataflatoxin B1 increases expressionISOSmarca4 (Mus musculus)6480464Aflatoxin B1 results in increased expression of SMARCA4 mRNACTDPMID:19770486
Smarca4Rataflatoxin B1 increases methylationISOSMARCA4 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of SMARCA4 intronCTDPMID:30157460
Smarca4Rataldehydo-D-glucose multiple interactionsISOSmarca4 (Mus musculus)6480464[MIR144 mRNA results in decreased expression of SMARCA4 protein] affects the susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] more ...CTDPMID:29457851
Smarca4Ratall-trans-retinoic acid decreases expressionEXP 6480464Tretinoin results in decreased expression of SMARCA4 mRNACTDPMID:24977338

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Biological Process
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Smarca4Rataorta development acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291 PMID:25807483RGDPMID:25807483
Smarca4Rataortic smooth muscle cell differentiation acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291 PMID:19342595RGDPMID:19342595
Smarca4Ratblastocyst growth acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:2386105 PMID:11163203RGDPMID:11163203
Smarca4Ratblastocyst hatching acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:2386105 PMID:11163203RGDPMID:11163203
Smarca4Ratblood vessel development acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:3605892 PMID:23319608RGDPMID:23319608
Smarca4Ratcell morphogenesis acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:2386105 more ...RGDPMID:16287714
Smarca4Ratchromatin organization involved_inIEAUniProtKB-KW:KW-01561600115GO_REF:0000043UniProtGO_REF:0000043
Smarca4Ratchromatin remodeling involved_inIEAARBA:ARBA000279941600115GO_REF:0000117UniProtGO_REF:0000117
Smarca4Ratchromatin remodeling  IDA 634124 RGD 
Smarca4Ratchromatin remodeling acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:3611933 PMID:16287714RGDPMID:16287714
Smarca4Ratchromatin remodeling involved_inIEAUniProtKB:P51532 and ensembl:ENSP000003438961600115GO_REF:0000107EnsemblGO_REF:0000107
Smarca4Ratchromatin remodeling involved_inISOSMARCA4 (Homo sapiens)1624291 PMID:10943845 more ...RGDPMID:10943845 more ...
Smarca4Ratcoronary vasculature development acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291 PMID:25807483RGDPMID:25807483
Smarca4Ratdefinitive erythrocyte differentiation acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:3611933 PMID:16287714RGDPMID:16287714
Smarca4Ratembryonic hindlimb morphogenesis acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:2177413 more ...RGDPMID:16192310
Smarca4Ratembryonic organ morphogenesis acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:2386105 more ...RGDPMID:16287714
Smarca4Ratepidermis morphogenesis acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:2177413 more ...RGDPMID:16192310
Smarca4Ratextracellular matrix organization acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:2450311 more ...RGDPMID:18267097
Smarca4Ratforebrain development acts_upstream_of_or_withinISOSmarca4 (Mus musculus)1624291MGI:2176173 more ...RGDPMID:16330018
Smarca4Ratgene expression acts_upstream_of_or_within_negative_effectISOSmarca4 (Mus musculus)1624291 PMID:25119045RGDPMID:25119045
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Cellular Component
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Smarca4Ratchromatin located_inISOSMARCA4 (Homo sapiens)1624291 PMID:12065415 and PMID:15774904RGDPMID:12065415 and PMID:15774904
Smarca4Ratchromatin located_inIEAUniProtKB:P51532 and ensembl:ENSP000003438961600115GO_REF:0000107EnsemblGO_REF:0000107
Smarca4Ratchromatin is_active_inIBACGD:CAL0000176922 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Smarca4Rateuchromatin located_inISOSmarca4 (Mus musculus)1624291 PMID:10318760RGDPMID:10318760
Smarca4Ratfibrillar center located_inIEAUniProtKB:P51532 and ensembl:ENSP000003438961600115GO_REF:0000107EnsemblGO_REF:0000107
Smarca4Ratfibrillar center located_inISOSMARCA4 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Smarca4Ratfibrillar center located_inIEAUniProtKB:A7E2E1 and ensembl:ENSP000003438961600115GO_REF:0000107EnsemblGO_REF:0000107
Smarca4Ratmale germ cell nucleus located_inISOSmarca4 (Mus musculus)1624291 PMID:16787967RGDPMID:16787967
Smarca4RatnBAF complex part_ofISSUniProtKB:Q3TKT41600115GO_REF:0000024UniProtGO_REF:0000024
Smarca4RatnBAF complex part_ofISOSmarca4 (Mus musculus)1624291 PMID:17640523 and PMID:23785148RGDPMID:17640523 and PMID:23785148
Smarca4RatnpBAF complex part_ofISOSMARCA4 (Homo sapiens)1624291 PMID:18816825RGDPMID:18816825
Smarca4RatnpBAF complex part_ofISOSmarca4 (Mus musculus)1624291 PMID:17640523 and PMID:23785148RGDPMID:17640523 and PMID:23785148
Smarca4RatnpBAF complex part_ofISSUniProtKB:Q3TKT41600115GO_REF:0000024UniProtGO_REF:0000024
Smarca4RatnpBAF complex part_ofIEAUniProtKB:P51532 and ensembl:ENSP000003438961600115GO_REF:0000107EnsemblGO_REF:0000107
Smarca4Ratnucleolus located_inISOSMARCA4 (Homo sapiens)1624291 PMID:22368283RGDPMID:22368283
Smarca4Ratnucleolus located_inIEAUniProtKB:P51532 and ensembl:ENSP000003438961600115GO_REF:0000107EnsemblGO_REF:0000107
Smarca4Ratnucleolus NOT|located_inISOSmarca4 (Mus musculus)1624291 PMID:10318760RGDPMID:10318760
Smarca4Ratnucleolus located_inIEAUniProtKB:A7E2E1 and ensembl:ENSP000003438961600115GO_REF:0000107EnsemblGO_REF:0000107
Smarca4Ratnucleolus located_inISOSMARCA4 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Smarca4Ratnucleoplasm located_inTAS 1600115Reactome:R-RNO-9614784ReactomeReactome:R-RNO-9614784
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Molecular Function
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Smarca4RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Smarca4RatATP binding enablesIEAInterPro:IPR000330 and InterPro:IPR0149781600115GO_REF:0000002InterProGO_REF:0000002
Smarca4RatATP hydrolysis activity enablesISOSmarca4 (Mus musculus)1624291 PMID:22513373RGDPMID:22513373
Smarca4RatATP-dependent activity, acting on DNA enablesISOSMARCA4 (Homo sapiens)1624291 PMID:8232556RGDPMID:8232556
Smarca4RatATP-dependent activity, acting on DNA enablesIEAUniProtKB:P51532 and ensembl:ENSP000003438961600115GO_REF:0000107EnsemblGO_REF:0000107
Smarca4RatATP-dependent chromatin remodeler activity enablesISOSmarca4 (Mus musculus)1624291 PMID:34910916RGDPMID:34910916
Smarca4Ratchromatin binding enablesISOSmarca4 (Mus musculus)1624291 PMID:10318760 more ...RGDPMID:10318760 more ...
Smarca4Ratchromatin binding  IDA 9586344 RGD 
Smarca4Ratchromatin binding enablesIBACGD:CAL0000192125 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Smarca4RatDNA binding enablesIBAMGI:88192 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Smarca4RatDNA polymerase binding enablesISOSMARCA4 (Homo sapiens)1624291UniProtKB:O14746 and PMID:19571879RGDPMID:19571879
Smarca4RatDNA polymerase binding enablesIEAUniProtKB:P51532 and ensembl:ENSP000003438961600115GO_REF:0000107EnsemblGO_REF:0000107
Smarca4RatDNA polymerase binding enablesISOSmarca4 (Mus musculus)1624291UniProtKB:O70372 and PMID:19571879RGDPMID:19571879
Smarca4Rathelicase activity enablesIEAUniProtKB-KW:KW-03471600115GO_REF:0000043UniProtGO_REF:0000043
Smarca4Rathistone binding enablesIEAInterPro:IPR0292951600115GO_REF:0000002InterProGO_REF:0000002
Smarca4Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Smarca4RatlncRNA binding enablesISOSmarca4 (Mus musculus)1624291MGI:3642848 PMID:25119045RGDPMID:25119045
Smarca4Ratnuclear androgen receptor binding enablesIEAUniProtKB:P51532 and ensembl:ENSP000003438961600115GO_REF:0000107EnsemblGO_REF:0000107
Smarca4Ratnuclear androgen receptor binding enablesISOSMARCA4 (Homo sapiens)1624291UniProtKB:P10275 and PMID:18487222RGDPMID:18487222
Smarca4Ratnucleosome array spacer activity enablesIBAFB:FBgn0011604 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
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Reference Title
Reference Citation
1. REST repression of neuronal genes requires components of the hSWI.SNF complex. Battaglioli E, etal., J Biol Chem. 2002 Oct 25;277(43):41038-45. Epub 2002 Aug 20.
2. Insights into role of bromodomain, testis-specific (Brdt) in acetylated histone H4-dependent chromatin remodeling in mammalian spermiogenesis. Dhar S, etal., J Biol Chem. 2012 Feb 24;287(9):6387-405. doi: 10.1074/jbc.M111.288167. Epub 2012 Jan 3.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. The role of Brg1, a catalytic subunit of mammalian chromatin-remodeling complexes, in T cell development. Gebuhr TC, etal., J Exp Med 2003 Dec 15;198(12):1937-49.
5. Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. Gordon MD and Nusse R, J Biol Chem. 2006 Aug 11;281(32):22429-33. Epub 2006 Jun 22.
6. ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Hargreaves DC and Crabtree GR, Cell Res. 2011 Mar;21(3):396-420. doi: 10.1038/cr.2011.32. Epub 2011 Mar 1.
7. Mammalian chromatin remodeling complex SWI/SNF is essential for enhanced expression of the albumin gene during liver development. Inayoshi Y, etal., J Biochem. 2006 Feb;139(2):177-88.
8. Novel glucocorticoid receptor coactivator effector mechanisms. Jenkins BD, etal., Trends Endocrinol Metab. 2001 Apr;12(3):122-6.
9. Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. Kadoch C and Crabtree GR, Cell. 2013 Mar 28;153(1):71-85. doi: 10.1016/j.cell.2013.02.036.
10. Genetic and epigenetic screening for gene alterations of the chromatin-remodeling factor, SMARCA4/BRG1, in lung tumors. Medina PP, etal., Genes Chromosomes Cancer. 2004 Oct;41(2):170-7.
11. SWI/SNF chromatin remodeling enzymes are associated with cardiac hypertrophy in a genetic rat model of hypertension. Mehrotra A, etal., J Cell Physiol. 2013 Dec;228(12):2337-42. doi: 10.1002/jcp.24404.
12. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
13. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. Glucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complex. Ostlund Farrants AK, etal., Mol Cell Biol 1997 Feb;17(2):895-905.
16. A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression. Qiu Z and Ghosh A, Neuron. 2008 Dec 10;60(5):775-87. doi: 10.1016/j.neuron.2008.09.040.
17. GOA pipeline RGD automated data pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. The bromodomain: From epigenome reader to druggable target. Sanchez R, etal., Biochim Biophys Acta. 2014 Aug;1839(8):676-685. doi: 10.1016/j.bbagrm.2014.03.011. Epub 2014 Mar 28.
1 to 20 of 28 rows
PMID:8208605   PMID:8232556   PMID:8804307   PMID:9603422   PMID:10318760   PMID:10943845   PMID:11078522   PMID:11163203   PMID:11726552   PMID:11950834   PMID:12065415   PMID:12368262  
PMID:12477932   PMID:12917342   PMID:15565649   PMID:15767674   PMID:15774904   PMID:16192310   PMID:16217013   PMID:16245309   PMID:16287714   PMID:16330018   PMID:16687403   PMID:16787967  
PMID:16880268   PMID:17074803   PMID:17582821   PMID:17640523   PMID:17666433   PMID:17938176   PMID:18267097   PMID:18487222   PMID:18816825   PMID:19342595   PMID:19571879   PMID:19946888  
PMID:20176728   PMID:20418909   PMID:21118511   PMID:22162999   PMID:22368283   PMID:22513373   PMID:22664934   PMID:23319608   PMID:23785148   PMID:24335282   PMID:25119045   PMID:25532521  
PMID:25569094   PMID:25633415   PMID:25807483   PMID:25972460   PMID:26138476   PMID:26388265   PMID:26582913   PMID:29374058   PMID:30973285   PMID:31939625   PMID:32105681   PMID:32987653  
PMID:38679350  



Smarca4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8828,438,370 - 28,535,071 (+)NCBIGRCr8
mRatBN7.2820,167,717 - 20,258,975 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl820,167,717 - 20,258,975 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx824,200,412 - 24,292,032 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0822,495,960 - 22,587,578 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0820,397,343 - 20,488,586 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0822,648,323 - 22,739,468 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,648,323 - 22,739,468 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,702,277 - 22,793,519 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4820,720,915 - 20,812,157 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1820,787,909 - 20,796,297 (+)NCBI
Celera821,558,796 - 21,650,002 (+)NCBICelera
Cytogenetic Map8q13NCBI
SMARCA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,961,030 - 11,062,273 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1910,960,932 - 11,079,426 (+)EnsemblGRCh38hg38GRCh38
GRCh371911,071,706 - 11,172,949 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,932,606 - 11,033,953 (+)NCBINCBI36Build 36hg18NCBI36
Build 341910,932,605 - 11,033,953NCBI
Celera1910,966,440 - 11,067,798 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef1910,649,456 - 10,749,943 (+)NCBIHuRef
CHM1_11911,072,949 - 11,174,225 (+)NCBICHM1_1
T2T-CHM13v2.01911,088,037 - 11,189,277 (+)NCBIT2T-CHM13v2.0
Smarca4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39921,527,377 - 21,615,526 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl921,527,465 - 21,615,526 (+)EnsemblGRCm39 Ensembl
GRCm38921,616,106 - 21,704,230 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl921,616,169 - 21,704,230 (+)EnsemblGRCm38mm10GRCm38
MGSCv37921,420,613 - 21,508,674 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36921,366,571 - 21,453,769 (+)NCBIMGSCv36mm8
Celera918,885,790 - 18,973,851 (+)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.84NCBI
Smarca4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554952,021,566 - 2,105,397 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554952,021,671 - 2,105,155 (+)NCBIChiLan1.0ChiLan1.0
SMARCA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22015,881,885 - 15,982,873 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11914,880,580 - 14,981,524 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01910,515,216 - 10,616,155 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11911,250,006 - 11,334,952 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1911,250,006 - 11,334,952 (+)Ensemblpanpan1.1panPan2
SMARCA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,175,489 - 50,268,865 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,175,687 - 50,268,836 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,049,076 - 50,142,476 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02050,696,689 - 50,790,220 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2050,696,700 - 50,790,215 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12049,906,864 - 50,000,228 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02050,333,903 - 50,427,442 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02050,576,222 - 50,669,723 (-)NCBIUU_Cfam_GSD_1.0
Smarca4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,107,992 - 209,201,474 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366591,169,792 - 1,249,213 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366591,152,846 - 1,246,718 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMARCA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl269,662,238 - 69,810,295 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1269,717,175 - 69,810,301 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2270,151,823 - 70,182,978 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMARCA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,943,162 - 10,044,476 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660749,892,049 - 9,994,184 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smarca4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,893,096 - 2,985,968 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248282,893,075 - 2,985,968 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Smarca4
259 total Variants

Predicted Target Of
Summary Value
Count of predictions:89
Count of miRNA genes:71
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000013165
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 23 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat

1 to 10 of 23 rows
AI111450  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2820,258,676 - 20,258,891 (+)MAPPERmRatBN7.2
Rnor_6.0822,739,170 - 22,739,384NCBIRnor6.0
Rnor_5.0822,793,221 - 22,793,435UniSTSRnor5.0
RGSC_v3.4820,811,859 - 20,812,073UniSTSRGSC3.4
Celera821,649,704 - 21,649,918UniSTS
Cytogenetic Map8q13UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 18 of 18 rows
RefSeq Transcripts NM_134368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC120728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ504723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC169035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X99723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 18 of 18 rows

Ensembl Acc Id: ENSRNOT00000013165   ⟹   ENSRNOP00000013166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl820,167,717 - 20,258,975 (+)Ensembl
Rnor_6.0 Ensembl822,648,323 - 22,739,468 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097065   ⟹   ENSRNOP00000081001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl820,167,717 - 20,256,996 (+)Ensembl
RefSeq Acc Id: NM_134368   ⟹   NP_599195
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,443,819 - 28,535,071 (+)NCBI
mRatBN7.2820,167,717 - 20,258,975 (+)NCBI
Rnor_6.0822,648,323 - 22,739,468 (+)NCBI
Rnor_5.0822,702,277 - 22,793,519 (+)NCBI
RGSC_v3.4820,720,915 - 20,812,157 (+)RGD
Celera821,558,796 - 21,650,002 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242598   ⟹   XP_006242660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,438,370 - 28,535,068 (+)NCBI
mRatBN7.2820,167,720 - 20,258,975 (+)NCBI
Rnor_6.0822,648,326 - 22,739,468 (+)NCBI
Rnor_5.0822,702,277 - 22,793,519 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006242599   ⟹   XP_006242661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,438,370 - 28,535,068 (+)NCBI
mRatBN7.2820,167,720 - 20,258,975 (+)NCBI
Rnor_6.0822,648,326 - 22,739,468 (+)NCBI
Rnor_5.0822,702,277 - 22,793,519 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006242601   ⟹   XP_006242663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,438,370 - 28,535,068 (+)NCBI
mRatBN7.2820,167,720 - 20,258,975 (+)NCBI
Rnor_6.0822,648,326 - 22,739,468 (+)NCBI
Rnor_5.0822,702,277 - 22,793,519 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063264830   ⟹   XP_063120900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,438,370 - 28,535,068 (+)NCBI
RefSeq Acc Id: XM_063264831   ⟹   XP_063120901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,444,515 - 28,535,068 (+)NCBI
RefSeq Acc Id: XM_063264832   ⟹   XP_063120902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,438,370 - 28,535,068 (+)NCBI
RefSeq Acc Id: XM_063264833   ⟹   XP_063120903
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,438,370 - 28,535,068 (+)NCBI
RefSeq Acc Id: XM_063264834   ⟹   XP_063120904
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,438,370 - 28,535,068 (+)NCBI
RefSeq Acc Id: XM_063264835   ⟹   XP_063120905
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,444,252 - 28,535,068 (+)NCBI
RefSeq Acc Id: XM_063264836   ⟹   XP_063120906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8828,444,515 - 28,535,068 (+)NCBI
1 to 5 of 13 rows
1 to 5 of 13 rows
RefSeq Acc Id: NP_599195   ⟸   NM_134368
- UniProtKB: Q8K1P7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006242660   ⟸   XM_006242598
- Peptide Label: isoform X3
- UniProtKB: Q8K1P7 (UniProtKB/Swiss-Prot),   G3V790 (UniProtKB/TrEMBL),   A6JNT8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242661   ⟸   XM_006242599
- Peptide Label: isoform X4
- UniProtKB: Q8K1P7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006242663   ⟸   XM_006242601
- Peptide Label: isoform X7
- UniProtKB: Q8K1P7 (UniProtKB/Swiss-Prot),   A6JNT9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013166   ⟸   ENSRNOT00000013165
Bromo   Helicase ATP-binding   Helicase C-terminal   HSA   QLQ

Name Modeler Protein Id AA Range Protein Structure
AF-Q8K1P7-F1-model_v2 AlphaFold Q8K1P7 1-1613 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695785
Promoter ID:EPDNEW_R6310
Type:initiation region
Name:Smarca4_1
Description:SWI/SNF related, matrix associated, actin dependent regulatorof chromatin, subfamily a, member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0822,648,490 - 22,648,550EPDNEW


1 to 40 of 59 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-31412 BioCyc
Ensembl Genes ENSRNOG00000009271 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000013165 ENTREZGENE
  ENSRNOT00000097065 ENTREZGENE
  ENSRNOT00000140415 ENTREZGENE
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot
  1.20.920.10 UniProtKB/Swiss-Prot
  3.40.5.120 UniProtKB/Swiss-Prot
  3.40.50.10810 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
InterPro BRG1 UniProtKB/Swiss-Prot
  BRK_domain UniProtKB/Swiss-Prot
  BRK_sf UniProtKB/Swiss-Prot
  Bromodomain UniProtKB/Swiss-Prot
  Bromodomain-like_sf UniProtKB/Swiss-Prot
  Bromodomain_CS UniProtKB/Swiss-Prot
  Gln-Leu-Gln_QLQ UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  HSA_dom UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  SnAC UniProtKB/Swiss-Prot
  SNF2-like_sf UniProtKB/Swiss-Prot
  SNF2/RAD54-like_C UniProtKB/Swiss-Prot
  SNF2_N UniProtKB/Swiss-Prot
NCBI Gene 171379 ENTREZGENE
PANTHER SNF2/RAD54 HELICASE FAMILY UniProtKB/Swiss-Prot
Pfam BRK UniProtKB/Swiss-Prot
  Bromodomain UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  HSA UniProtKB/Swiss-Prot
  QLQ UniProtKB/Swiss-Prot
  SnAC UniProtKB/Swiss-Prot
  SNF2_N UniProtKB/Swiss-Prot
PhenoGen Smarca4 PhenoGen
PRINTS BROMODOMAIN UniProtKB/Swiss-Prot
PROSITE BROMODOMAIN_1 UniProtKB/Swiss-Prot
  BROMODOMAIN_2 UniProtKB/Swiss-Prot
  HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
1 to 40 of 59 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-11-08 Smarca4  SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4  Smarca4  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Smarca4  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Smarca4  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4      Symbol and Name status set to provisional 70820 PROVISIONAL