(+)-pilocarpine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 1 more ... CTD PMID:19927300 (+)-pilocarpine increases activity ISO MAPK8 (Homo sapiens) 6480464 Pilocarpine results in increased activity of MAPK8 protein CTD PMID:19927300 (+)-taxifolin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 taxifolin inhibits the reaction [IFNG protein results in increased phosphorylation of MAPK8 protein] CTD PMID:12044887 (-)-anisomycin increases activity ISO MAPK8 (Homo sapiens) 6480464 Anisomycin results in increased activity of MAPK8 protein CTD PMID:12902192 (-)-anisomycin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Anisomycin inhibits the reaction [rutecarpine inhibits the reaction [Glucose results in increased phosphorylation of MAPK8 protein]] more ... CTD PMID:15737997 more ... (-)-anisomycin increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Anisomycin results in increased phosphorylation of MAPK8 protein CTD PMID:15772366 and PMID:16038797 (-)-anisomycin multiple interactions EXP 6480464 Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15961565 (-)-anisomycin multiple interactions ISO Mapk8 (Mus musculus) 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 and 4-d)pyrimidine inhibits the reaction [Anisomycin results in increased phosphorylation of MAPK8 protein] CTD PMID:15772366 (-)-anisomycin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Anisomycin results in increased phosphorylation of MAPK8 protein CTD PMID:12967334 and PMID:33075463 (-)-Arctigenin multiple interactions ISO Mapk8 (Mus musculus) 6480464 arctigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21048310 (-)-citrinin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Citrinin results in increased phosphorylation of MAPK8 protein CTD PMID:19361540 (-)-epigallocatechin 3-gallate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK8 protein] and epigallocatechin gallate inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK8 protein] CTD PMID:19944065 and PMID:31252129 (-)-epigallocatechin 3-gallate decreases expression ISO MAPK8 (Homo sapiens) 6480464 epigallocatechin gallate results in decreased expression of MAPK8 protein CTD PMID:35218280 (-)-epigallocatechin 3-gallate increases activity ISO MAPK8 (Homo sapiens) 6480464 epigallocatechin gallate results in increased activity of MAPK8 protein CTD PMID:15705601 (-)-matairesinol multiple interactions ISO Mapk8 (Mus musculus) 6480464 matairesinol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21048310 (1->4)-beta-D-glucan multiple interactions ISO Mapk8 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MAPK8 mRNA CTD PMID:36331819 (R)-lipoic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA CTD PMID:23830814 (R)-noradrenaline multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK8 protein] CTD PMID:17041759 (R)-noradrenaline increases phosphorylation EXP 6480464 Norepinephrine results in increased phosphorylation of MAPK8 protein CTD PMID:17041759 (R)-salsolinol increases activity EXP 6480464 salsolinol results in increased activity of MAPK8 protein CTD PMID:11502874 (R,R,R)-alpha-tocopherol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein] more ... CTD PMID:12684028 more ... (R,R,R)-alpha-tocopherol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein CTD PMID:20686688 (S)-colchicine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Colchicine results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 (S)-colchicine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 TP53 protein affects the reaction [Colchicine results in increased phosphorylation of MAPK8 protein] CTD PMID:12221076 (S)-naringenin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 naringenin results in increased phosphorylation of MAPK8 protein CTD PMID:27838343 (S)-nicotine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11592233 and PMID:20727180 (S)-nicotine increases activity EXP 6480464 Nicotine results in increased activity of MAPK8 protein CTD PMID:17021677 (S)-nicotine multiple interactions EXP 6480464 Nicotine promotes the reaction [MAPK8 protein results in increased phosphorylation of JUN protein] CTD PMID:17021677 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of MAPK8 mRNA CTD PMID:20426880 (S)-nicotine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:20727180 (S)-nicotine increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:21511693 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions ISO Mapk8 (Mus musculus) 6480464 o more ... CTD PMID:18840457 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [o and p'-DDT results in increased phosphorylation of MAPK8 protein] CTD PMID:20678559 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 o and p'-DDT results in increased phosphorylation of MAPK8 protein CTD PMID:20678559 1,2-dichloroethane decreases expression ISO Mapk8 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of MAPK8 mRNA CTD PMID:28960355 1,2-dimethylhydrazine decreases expression ISO Mapk8 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of MAPK8 mRNA CTD PMID:22206623 1,3-dichloropropan-2-ol increases phosphorylation EXP 6480464 1 and 3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein CTD PMID:26143167 1,3-dichloropropan-2-ol increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 1 and 3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein CTD PMID:29248572 1,3-dichloropropan-2-ol multiple interactions ISO Mapk8 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [1 and 3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein] CTD PMID:29248572 1,3-Dinitropyrene increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 1 and 3-dinitropyrene results in increased phosphorylation of MAPK8 protein CTD PMID:17240030 1,4-dithiothreitol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein] CTD PMID:10644709 1,4-phenylenediamine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 4-phenylenediamine results in increased phosphorylation of MAPK8 protein CTD PMID:23172806 1,8-cineole multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Eucalyptol inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased phosphorylation of MAPK8 protein] CTD PMID:23872422 1-chloro-2,4,6-trinitrobenzene increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Picryl Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:20381601 1-chloro-2,4-dinitrobenzene increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased phosphorylation of MAPK8 protein CTD PMID:18495191 1-fluoro-2,4-dinitrobenzene increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 1-fluoro-2,4-dinitrobenzene multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 1-hydroxy-2-naphthoic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide and E coli O55-B5 results in increased phosphorylation of MAPK8 protein] CTD PMID:21667204 1-naphthyl isothiocyanate increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 1-Naphthylisothiocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:36460194 1-naphthyl isothiocyanate multiple interactions ISO Mapk8 (Mus musculus) 6480464 3-(5-(4-(cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-hydroxy-1 more ... CTD PMID:36460194 1-nitropyrene increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 1-nitropyrene results in increased phosphorylation of MAPK8 protein CTD PMID:17240030 1-nitropyrene increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 1-nitropyrene results in increased phosphorylation of MAPK8 protein CTD PMID:37993079 17beta-estradiol decreases expression ISO MAPK8 (Homo sapiens) 6480464 Estradiol results in decreased expression of MAPK8 mRNA CTD PMID:16029874 17beta-estradiol multiple interactions EXP 6480464 Estradiol inhibits the reaction [Gentamicins results in increased activity of MAPK8 protein] CTD PMID:20074632 2''-galloylhyperin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:28213291 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 2' more ... CTD PMID:31029725 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone multiple interactions ISO Mapk8 (Mus musculus) 6480464 2' more ... CTD PMID:31029725 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO MAPK8 (Homo sapiens) 6480464 2 more ... CTD PMID:22543052 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO MAPK8 (Homo sapiens) 6480464 ERN1 protein affects the reaction [2 more ... CTD PMID:22543052 2,3',4,4',5-Pentachlorobiphenyl multiple interactions EXP 6480464 MAPK8 affects the reaction [2 more ... CTD PMID:26519956 2,3',4,4',5-Pentachlorobiphenyl increases phosphorylation EXP 6480464 2 more ... CTD PMID:36450500 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO Mapk8 (Mus musculus) 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine affects response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 affects the susceptibility to Tetrachlorodibenzodioxin CTD PMID:9677421 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of MAPK8 protein CTD PMID:24469321 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Mapk8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of MAPK8 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Mapk8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of MAPK8 mRNA CTD PMID:19465110 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of MAPK8 protein CTD PMID:20181658 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Mapk8 (Mus musculus) 6480464 MAPK8 protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of INSR protein] more ... CTD PMID:20181658 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 1 more ... CTD PMID:16619036 and PMID:24469321 2,3,7,8-tetrachlorodibenzodioxine increases response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 results in increased susceptibility to Tetrachlorodibenzodioxin CTD PMID:9677421 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of MAPK8 mRNA CTD PMID:23537331 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP 6480464 Verapamil inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15936777 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine increases phosphorylation EXP 6480464 4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased phosphorylation of MAPK8 protein CTD PMID:30790395 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions EXP 6480464 gastrodin inhibits the reaction [4-iodo-2 more ... CTD PMID:30790395 2-acetamidofluorene multiple interactions EXP 6480464 2-Acetylaminofluorene affects the phosphorylation of and affects the activity of MAPK8 protein CTD PMID:17546627 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18080321 more ... 2-amino-2-deoxy-D-glucopyranose increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Glucosamine analog results in increased phosphorylation of MAPK8 protein CTD PMID:18080321 2-butoxyethanol decreases expression ISO Mapk8 (Mus musculus) 6480464 n-butoxyethanol results in decreased expression of MAPK8 mRNA CTD PMID:19812364 2-methyl-6-(phenylethynyl)pyridine multiple interactions ISO Mapk8 (Mus musculus) 6480464 6-methyl-2-(phenylethynyl)pyridine affects the reaction [[GOPC protein affects the susceptibility to Oxidopamine] which affects the phosphorylation of MAPK8 protein] more ... CTD PMID:29458170 and PMID:33571554 2-trans,6-trans-farnesyl diphosphate multiple interactions ISO Mapk8 (Mus musculus) 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 3',5'-cyclic GMP increases activity ISO MAPK8 (Homo sapiens) 6480464 Cyclic GMP analog results in increased activity of MAPK8 protein CTD PMID:11051267 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions EXP 6480464 Puromycin Aminonucleoside binds to and results in increased activity of MAPK8 protein CTD PMID:15351692 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of MAPK8 mRNA CTD PMID:28970181 3,3',5,5'-tetrabromobisphenol A multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein] and diphenyleneiodonium inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein] CTD PMID:30766661 3,3',5,5'-tetrabromobisphenol A increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein CTD PMID:30766661 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione decreases expression ISO MAPK8 (Homo sapiens) 6480464 bisindolylmaleimide I results in decreased expression of MAPK8 mRNA CTD PMID:28780155 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO MAPK8 (Homo sapiens) 6480464 bisindolylmaleimide I inhibits the reaction [puag-haad results in increased expression of MAPK8 mRNA] CTD PMID:28780155 3-acetyldeoxynivalenol multiple interactions ISO Mapk8 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of MAPK8 mRNA] CTD PMID:35413383 3-acetyldeoxynivalenol increases expression ISO Mapk8 (Mus musculus) 6480464 3-acetyldeoxynivalenol results in increased expression of MAPK8 mRNA CTD PMID:35413383 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Mapk8 (Mus musculus) 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein and pentagalloylglucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:30721698 3-Methoxynobiletin affects phosphorylation ISO MAPK8 (Homo sapiens) 6480464 3 more ... CTD PMID:29470423 3-methylcholanthrene multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Methylcholanthrene results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16619036 3-O-Caffeoyl-1-O-methylquinic acid increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 3-O-caffeoyl-1-methylquinic acid results in increased phosphorylation of MAPK8 protein CTD PMID:16631525 3-phenylprop-2-enal multiple interactions ISO MAPK8 (Homo sapiens) 6480464 cinnamaldehyde results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15964311 3-phenylprop-2-enal increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 cinnamaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:21469739 3-phenylprop-2-enal multiple interactions ISO Mapk8 (Mus musculus) 6480464 cinnamaldehyde inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:17868967 4,4'-diaminodiphenylmethane increases expression ISO Mapk8 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of MAPK8 mRNA CTD PMID:18648102 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 4 more ... CTD PMID:19815690 4-hydroxynon-2-enal increases activity ISO MAPK8 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in increased activity of MAPK8 protein CTD PMID:11488593 4-hydroxynon-2-enal increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein CTD PMID:24825450 4-hydroxynon-2-enal affects response to substance ISO Mapk8 (Mus musculus) 6480464 MAPK8 protein affects the susceptibility to 4-hydroxy-2-nonenal CTD PMID:17263905 4-hydroxynon-2-enal increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein CTD PMID:15064094 4-hydroxynon-2-enal increases activity ISO Mapk8 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in increased activity of MAPK8 protein CTD PMID:17263905 4-hydroxynon-2-enal multiple interactions ISO Mapk8 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15064094 and PMID:16322078 4-hydroxynon-2-enal multiple interactions ISO MAPK8 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein and Hydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:12684028 4-hydroxyphenyl retinamide increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Fenretinide results in increased phosphorylation of MAPK8 protein CTD PMID:16407847 4-hydroxyphenyl retinamide increases activity ISO MAPK8 (Homo sapiens) 6480464 Fenretinide results in increased activity of MAPK8 protein CTD PMID:16407847 4-hydroxyphenyl retinamide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [IL24 protein co-treated with Fenretinide] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:15580305 and PMID:16407847 4-nonylphenol increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 4-nonylphenol analog results in increased phosphorylation of MAPK8 protein CTD PMID:27086933 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Cytotoxins results in increased phosphorylation of MAPK8 protein] CTD PMID:21147958 4-phenylbutyric acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of MAPK8 mRNA] CTD PMID:35413383 4-phenylbutyric acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased phosphorylation of MAPK8 protein] CTD PMID:31364909 4-vinylcyclohexene dioxide increases expression ISO Mapk8 (Mus musculus) 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of MAPK8 mRNA CTD PMID:20829426 5-aza-2'-deoxycytidine decreases expression ISO Mapk8 (Mus musculus) 6480464 Decitabine results in decreased expression of MAPK8 mRNA CTD PMID:27915011 5-aza-2'-deoxycytidine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Decitabine inhibits the reaction [nickel monoxide results in increased expression of and results in increased phosphorylation of MAPK8 protein] CTD PMID:36066426 5-chloro-7-iodoquinolin-8-ol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Clioquinol co-treated with Copper] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:16648635 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:33759307 and PMID:36863560 7,12-dimethyltetraphene multiple interactions EXP 6480464 betulin inhibits the reaction [9 more ... CTD PMID:33759307 acetaldehyde increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Acetaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:19110045 acetaldehyde increases activity EXP 6480464 Acetaldehyde results in increased activity of MAPK8 protein CTD PMID:10733585 acetaldehyde multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Hesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK8 protein] CTD PMID:19110045 acetic acid increases phosphorylation EXP 6480464 Acetic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:32045587 acetic acid multiple interactions EXP 6480464 Gliclazide inhibits the reaction [Acetic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:32045587 acetylleucyl-leucyl-norleucinal increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 acetylleucyl-leucyl-norleucinal results in increased phosphorylation of MAPK8 protein CTD PMID:15618349 Aciculatin multiple interactions ISO Mapk8 (Mus musculus) 6480464 aciculatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21548916 acrolein multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Phenylbutyrates inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] and RTKI cpd inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] CTD PMID:11329622 and PMID:18951912 acrolein increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Acrolein results in increased phosphorylation of MAPK8 protein CTD PMID:11329622 more ... acrolein multiple interactions EXP 6480464 SB 203580 promotes the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] CTD PMID:12487375 acrolein increases phosphorylation EXP 6480464 [Acrolein results in increased phosphorylation of MAPK8 protein] which results in increased phosphorylation of JUN protein and Acrolein results in increased phosphorylation of MAPK8 protein CTD PMID:12487375 acrylamide multiple interactions ISO Mapk8 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:25531190 and PMID:31081568 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of MAPK8 protein modified form CTD PMID:29426002 acrylamide increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Acrylamide results in increased phosphorylation of MAPK8 protein CTD PMID:25531190 and PMID:31081568 acrylonitrile increases expression ISO Mapk8 (Mus musculus) 6480464 Acrylonitrile results in increased expression of MAPK8 mRNA CTD PMID:35429547 ADP multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein] CTD PMID:24466103 afimoxifene decreases response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 results in decreased susceptibility to afimoxifene CTD PMID:21233418 aldehydo-D-glucosamine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18080321 more ... aldehydo-D-glucosamine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Glucosamine analog results in increased phosphorylation of MAPK8 protein CTD PMID:18080321 aldehydo-D-glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:19861503 and PMID:34801538 aldehydo-D-glucose increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:36928891 aldehydo-D-glucose multiple interactions EXP 6480464 [[Paraquat results in increased phosphorylation of MAPK8 protein] which results in decreased abundance of Insulin] which results in increased abundance of Glucose more ... CTD PMID:34801538 and PMID:36394833 aldehydo-D-glucose multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Anisomycin inhibits the reaction [rutecarpine inhibits the reaction [Glucose results in increased phosphorylation of MAPK8 protein]] more ... CTD PMID:14505347 and PMID:36928891 Alisol B multiple interactions ISO Mapk8 (Mus musculus) 6480464 alisol B inhibits the reaction [[Dietary Fats co-treated with Carbon Tetrachloride] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:20412788 and PMID:35745142 all-trans-retinoic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 pyrazolanthrone inhibits the reaction [Tretinoin results in increased activity of MAPK8 protein] and SPAG9 protein promotes the reaction [Tretinoin results in increased phosphorylation of MAPK8 protein] CTD PMID:16619266 and PMID:21626648 all-trans-retinoic acid increases activity ISO Mapk8 (Mus musculus) 6480464 Tretinoin results in increased activity of MAPK8 protein CTD PMID:21626648 all-trans-retinoic acid decreases expression ISO Mapk8 (Mus musculus) 6480464 Tretinoin results in decreased expression of MAPK8 mRNA CTD PMID:22498432 all-trans-retinoic acid increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Tretinoin results in increased phosphorylation of MAPK8 protein CTD PMID:16619266 all-trans-retinoic acid decreases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Tretinoin results in decreased phosphorylation of MAPK8 protein CTD PMID:16084493 alpha-Chaconine multiple interactions ISO Mapk8 (Mus musculus) 6480464 alpha-chaconine inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:25913072 alpha-D-galactose increases expression EXP 6480464 Galactose results in increased expression of MAPK8 mRNA CTD PMID:35259467 alpha-D-galactose multiple interactions EXP 6480464 Galactose promotes the reaction [sodium arsenite results in increased expression of MAPK8 mRNA] CTD PMID:35259467 alpha-mangostin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 mangostin analog results in increased phosphorylation of MAPK8 protein CTD PMID:28722351 alvocidib multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK8 protein and alvocidib promotes the reaction [Bortezomib results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15039284 and PMID:15634644 amidotrizoic acid increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Diatrizoate results in increased phosphorylation of MAPK8 protein CTD PMID:21036957 amiloride multiple interactions ISO Mapk8 (Mus musculus) 6480464 Amiloride inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein] CTD PMID:19815690 amino acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 Amino Acids inhibits the reaction [KL gene mutant form results in increased phosphorylation of MAPK8 protein] and H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in increased phosphorylation of MAPK8 protein]] CTD PMID:25309793 amiodarone increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Amiodarone results in increased phosphorylation of MAPK8 protein CTD PMID:34259586 amiodarone multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein] CTD PMID:25073960 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of MAPK8 mRNA CTD PMID:16483693 ammonium chloride multiple interactions EXP 6480464 TLR5 gene mutant form inhibits the reaction [Ammonium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:30508503 ammonium chloride increases phosphorylation EXP 6480464 Ammonium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:30508503 amodiaquine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [CYP2C8 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK8 protein and [CYP3A4 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK8 protein CTD PMID:31629065 amphetamine multiple interactions EXP 6480464 MAPK8 protein promotes the reaction [Amphetamine results in increased expression of GJA1 protein] CTD PMID:15194466 Anemoside B4 multiple interactions ISO Mapk8 (Mus musculus) 6480464 anemoside B4 inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:32991863 anethole multiple interactions ISO MAPK8 (Homo sapiens) 6480464 anethole inhibits the reaction [TNF protein results in increased activity of MAPK8 protein] CTD PMID:10871845 aniline increases phosphorylation EXP 6480464 aniline results in increased phosphorylation of MAPK8 protein CTD PMID:16169568 and PMID:18420242 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:14610070 more ... anthra[1,9-cd]pyrazol-6(2H)-one decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 pyrazolanthrone results in decreased phosphorylation of MAPK8 protein CTD PMID:34076342 anthra[1,9-cd]pyrazol-6(2H)-one decreases expression EXP 329853763 SP600125 decreases expression of protein in oxygen-glucose deprived rat neuronal PC12 cells RGD anthra[1,9-cd]pyrazol-6(2H)-one increases expression EXP 6480464 pyrazolanthrone results in increased expression of MAPK8 protein CTD PMID:16046226 anthra[1,9-cd]pyrazol-6(2H)-one decreases phosphorylation EXP 6480464 pyrazolanthrone results in decreased phosphorylation of MAPK8 protein CTD PMID:22085843 and PMID:24833599 anthra[1,9-cd]pyrazol-6(2H)-one decreases activity ISO MAPK8 (Homo sapiens) 6480464 pyrazolanthrone results in decreased activity of MAPK8 protein CTD PMID:12534346 and PMID:21112663 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 [cypermethrin co-treated with pyrazolanthrone] results in decreased phosphorylation of MAPK8 protein more ... CTD PMID:16687388 more ... anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Mapk8 (Mus musculus) 6480464 [pyrazolanthrone co-treated with 6 more ... CTD PMID:16374168 more ... antimony trichloride multiple interactions ISO Mapk8 (Mus musculus) 6480464 [arsenic trichloride co-treated with antimony trichloride] results in increased expression of MAPK8 mRNA and arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of MAPK8 protein] CTD PMID:34091186 antimony trichloride increases expression ISO Mapk8 (Mus musculus) 6480464 antimony trichloride results in increased expression of MAPK8 protein CTD PMID:34091186 Antimony trioxide increases activity ISO MAPK8 (Homo sapiens) 6480464 antimony trioxide results in increased activity of MAPK8 protein CTD PMID:16112521 Antimony trioxide multiple interactions ISO Mapk8 (Mus musculus) 6480464 MAP2K4 protein affects the reaction [antimony trioxide results in increased activity of MAPK8 protein] CTD PMID:16112521 Antimony trioxide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein more ... CTD PMID:16112521 ANTIMYCIN decreases phosphorylation ISO Mapk8 (Mus musculus) 6480464 antimycin results in decreased phosphorylation of MAPK8 protein CTD PMID:33290831 Apicularen A multiple interactions ISO Mapk8 (Mus musculus) 6480464 apicularen A results in increased phosphorylation of and results in increased expression of MAPK8 protein CTD PMID:15561798 apigenin multiple interactions EXP 6480464 Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] and Apigenin inhibits the reaction [Methylmercury Compounds results in increased expression of MAPK8 protein] CTD PMID:25557508 and PMID:35373622 apocynin multiple interactions ISO Mapk8 (Mus musculus) 6480464 acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:20354174 apocynin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21391979 more ... apremilast multiple interactions EXP 6480464 apremilast inhibits the reaction [carfilzomib results in increased expression of MAPK8 mRNA] CTD PMID:27785949 arachidonic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 MAPK8 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein] more ... CTD PMID:19540902 Arctiin multiple interactions ISO Mapk8 (Mus musculus) 6480464 arctiin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21048310 arecoline increases phosphorylation EXP 6480464 Arecoline results in increased phosphorylation of MAPK8 protein CTD PMID:34999050 aristolochic acid A decreases expression ISO MAPK8 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of MAPK8 mRNA CTD PMID:33212167 arsane multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Arsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein and MAPK8 protein affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ATF3 protein] CTD PMID:14633691 and PMID:33921748 arsane increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Arsenic results in increased phosphorylation of MAPK8 protein CTD PMID:35031324 arsane multiple interactions ISO Mapk8 (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] and [sodium arsenite results in increased abundance of Arsenic] which results in decreased phosphorylation of MAPK8 protein CTD PMID:33049506 arsane multiple interactions EXP 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of MAPK8 mRNA more ... CTD PMID:11756236 more ... arsenic atom multiple interactions EXP 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of MAPK8 mRNA more ... CTD PMID:11756236 more ... arsenic atom increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Arsenic results in increased phosphorylation of MAPK8 protein CTD PMID:35031324 arsenic atom multiple interactions ISO Mapk8 (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] and [sodium arsenite results in increased abundance of Arsenic] which results in decreased phosphorylation of MAPK8 protein CTD PMID:33049506 arsenic atom multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Arsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein and MAPK8 protein affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ATF3 protein] CTD PMID:14633691 and PMID:33921748 arsenic trichloride multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of MAPK8 protein] CTD PMID:22696236 arsenic trichloride increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 arsenic trichloride results in increased phosphorylation of MAPK8 protein CTD PMID:22696236 and PMID:24434654 arsenic trichloride multiple interactions ISO Mapk8 (Mus musculus) 6480464 [arsenic trichloride co-treated with antimony trichloride] results in increased expression of MAPK8 mRNA more ... CTD PMID:22696236 and PMID:34091186 arsenite(3-) decreases expression ISO Mapk8 (Mus musculus) 6480464 arsenite results in decreased expression of MAPK8 mRNA CTD PMID:18191166 arsenite(3-) multiple interactions ISO MAPK8 (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to MAPK8 mRNA] CTD PMID:32406909 arsenite(3-) increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:19808956 arsenite(3-) multiple interactions ISO Mapk8 (Mus musculus) 6480464 arsenite results in increased phosphorylation of and results in increased activity of MAPK8 protein and MAP3K8 protein affects the reaction [arsenite results in increased phosphorylation of MAPK8 protein] CTD PMID:15014438 and PMID:19808956 arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:21145380 more ... arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of MAPK8 mRNA CTD PMID:34037972 arsenous acid increases expression ISO Mapk8 (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of MAPK8 mRNA and Arsenic Trioxide results in increased expression of MAPK8 protein CTD PMID:34091186 arsenous acid increases expression ISO MAPK8 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of MAPK8 protein CTD PMID:17374990 arsenous acid increases activity ISO MAPK8 (Homo sapiens) 6480464 Arsenic Trioxide results in increased activity of MAPK8 protein CTD PMID:11304686 more ... arsenous acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:14610070 more ... arsenous acid increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:18412143 more ... arsenous acid multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21145380 more ... arsenous acid increases response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:20799280 arsenous acid increases response to substance ISO Mapk8 (Mus musculus) 6480464 MAPK8 protein results in increased susceptibility to Arsenic Trioxide and MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:16818652 arsenous acid affects response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 protein affects the susceptibility to Arsenic Trioxide CTD PMID:16818652 arsenous acid increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:15688020 asbestos multiple interactions ISO Mapk8 (Mus musculus) 6480464 Asbestos results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:11280724 asiatic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] and asiatic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] CTD PMID:30802477 astaxanthin multiple interactions ISO Mapk8 (Mus musculus) 6480464 astaxanthine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased phosphorylation of MAPK8 protein] CTD PMID:33008094 atrazine increases expression ISO MAPK8 (Homo sapiens) 6480464 Atrazine results in increased expression of MAPK8 mRNA CTD PMID:22378314 atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of MAPK8 mRNA CTD PMID:31187311 atropine multiple interactions EXP 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 aureusidin multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK8 protein] CTD PMID:31790703 aureusidin increases phosphorylation EXP 6480464 aureusidin results in increased phosphorylation of MAPK8 protein CTD PMID:31790703 Azaspiracid multiple interactions ISO Mapk8 (Mus musculus) 6480464 4 more ... CTD PMID:19815690 bafilomycin A1 increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 bafilomycin A1 results in increased phosphorylation of MAPK8 protein CTD PMID:31310755 baicalein multiple interactions ISO MAPK8 (Homo sapiens) 6480464 baicalein results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:10718847 BAPTA multiple interactions ISO MAPK8 (Homo sapiens) 6480464 1 more ... CTD PMID:19927300 bathocuproine disulfonic acid multiple interactions EXP 6480464 bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] more ... CTD PMID:10941151 more ... benomyl increases expression EXP 6480464 Benomyl results in increased expression of MAPK8 mRNA CTD PMID:33930522 benzo[a]pyrene multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Nitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of MAPK8 protein] and pyrazolanthrone inhibits the reaction [Benzo(a)pyrene results in increased expression of MAPK8 protein] CTD PMID:16041517 benzo[a]pyrene affects methylation ISO MAPK8 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of MAPK8 promoter CTD PMID:27901495 benzo[a]pyrene increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein CTD PMID:18321868 and PMID:35777681 benzo[a]pyrene multiple interactions ISO Mapk8 (Mus musculus) 6480464 Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein] and necrostatin-1 inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein] CTD PMID:18321868 and PMID:35777681 benzo[a]pyrene increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein CTD PMID:15698582 benzo[a]pyrene increases expression ISO MAPK8 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of MAPK8 protein CTD PMID:16041517 benzo[a]pyrene diol epoxide I increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 7 more ... CTD PMID:21501596 benzo[a]pyrene diol epoxide I increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 benzo[a]pyrene diol epoxide I multiple interactions ISO Mapk8 (Mus musculus) 6480464 AG 1879 inhibits the reaction [7 more ... CTD PMID:21501596 Benzo[a]pyrene-7,8-diol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 benzo(a)pyrene 7 and 8-dihydrodiol results in increased phosphorylation of MAPK8 protein CTD PMID:15698582 and PMID:22053912 benzyl isothiocyanate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [benzyl isothiocyanate results in increased phosphorylation of MAPK8 protein] CTD PMID:31587482 benzyl isothiocyanate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 benzyl isothiocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:31587482 berberine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Berberine co-treated with Cisplatin] results in increased phosphorylation of MAPK8 protein and Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased phosphorylation of MAPK8 protein] CTD PMID:36070022 beta-D-glucosamine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18080321 more ... beta-D-glucosamine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Glucosamine analog results in increased phosphorylation of MAPK8 protein CTD PMID:18080321 beta-hexachlorocyclohexane multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein] CTD PMID:19760616 beta-hexachlorocyclohexane increases phosphorylation EXP 6480464 beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein CTD PMID:19760616 betulin multiple interactions EXP 6480464 betulin inhibits the reaction [9 more ... CTD PMID:33759307 bicuculline multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Bicuculline co-treated with Ethanol] results in increased expression of MAPK8 protein CTD PMID:29044621 bis(2-chloroethyl) sulfide increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Mustard Gas results in increased phosphorylation of MAPK8 protein CTD PMID:18200059 bis(2-ethylhexyl) phthalate multiple interactions ISO Mapk8 (Mus musculus) 6480464 Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein] CTD PMID:33484791 bis(2-ethylhexyl) phthalate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased phosphorylation of MAPK8 protein CTD PMID:30944277 and PMID:34822940 bis(2-ethylhexyl) phthalate increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased phosphorylation of MAPK8 protein CTD PMID:33484791 bisphenol A multiple interactions EXP 6480464 bisphenol A results in increased expression of and results in increased phosphorylation of MAPK8 protein CTD PMID:17322771 bisphenol A increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 bisphenol A results in increased phosphorylation of MAPK8 protein CTD PMID:33039870 and PMID:36232920 bisphenol A multiple interactions ISO MAPK8 (Homo sapiens) 6480464 1 more ... CTD PMID:33039870 bisphenol A increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 bisphenol A results in increased phosphorylation of MAPK8 protein CTD PMID:32575098 bisphenol A decreases expression ISO Mapk8 (Mus musculus) 6480464 bisphenol A results in decreased expression of MAPK8 mRNA CTD PMID:33221593 bisphenol A decreases expression ISO MAPK8 (Homo sapiens) 6480464 bisphenol A results in decreased expression of MAPK8 mRNA CTD PMID:29275510 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of MAPK8 mRNA CTD PMID:25181051 bisphenol A increases phosphorylation EXP 6480464 bisphenol A results in increased phosphorylation of MAPK8 protein CTD PMID:20096755 and PMID:30496632 Bisphenol A diglycidyl ether multiple interactions EXP 6480464 2 and 2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Ursolic Acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein]] CTD PMID:27274199 bleomycin A2 multiple interactions ISO Mapk8 (Mus musculus) 6480464 Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of MAPK8 protein] CTD PMID:35716765 bleomycin A2 increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Bleomycin results in increased phosphorylation of MAPK8 protein CTD PMID:35716765 bortezomib multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [[Bortezomib co-treated with Butyrates] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:12893773 more ... bortezomib increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Bortezomib results in increased phosphorylation of MAPK8 protein CTD PMID:18559525 bosutinib multiple interactions ISO MAPK8 (Homo sapiens) 6480464 bosutinib affects the reaction [linsidomine results in increased phosphorylation of MAPK8 protein] CTD PMID:34519134 bufalin decreases activity ISO MAPK8 (Homo sapiens) 6480464 bufalin results in decreased activity of MAPK8 protein CTD PMID:21922632 bupropion multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Bupropion results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:21354251 butanal decreases expression ISO MAPK8 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of MAPK8 mRNA CTD PMID:26079696 butein multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [butein results in increased phosphorylation of MAPK8 protein] CTD PMID:35130734 butein increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 butein results in increased phosphorylation of MAPK8 protein CTD PMID:35130734 butylated hydroxyanisole multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK8 protein] CTD PMID:16407847 butylated hydroxyanisole multiple interactions EXP 6480464 Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein] CTD PMID:18593901 butylated hydroxyanisole multiple interactions ISO Mapk8 (Mus musculus) 6480464 Butylated Hydroxyanisole inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein] more ... CTD PMID:15989949 more ... butyric acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:28600122 butyric acid increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Butyric Acid results in increased phosphorylation of MAPK8 protein CTD PMID:28600122 C.I. Natural Red 20 multiple interactions EXP 6480464 shikonin inhibits the reaction [Glutamic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:35028790 cadmium atom multiple interactions ISO Mapk8 (Mus musculus) 6480464 1 more ... CTD PMID:15254339 more ... cadmium atom increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Cadmium results in increased phosphorylation of MAPK8 protein CTD PMID:26187450 and PMID:26514923 cadmium atom multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein more ... CTD PMID:26187450 more ... cadmium atom increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Cadmium results in increased phosphorylation of MAPK8 protein CTD PMID:15212812 and PMID:15254339 cadmium atom decreases response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 mutant form results in decreased susceptibility to Cadmium CTD PMID:10874022 cadmium atom increases phosphorylation EXP 6480464 Cadmium results in increased phosphorylation of MAPK8 protein CTD PMID:18463101 cadmium atom affects response to substance EXP 6480464 MAPK8 protein affects the susceptibility to Cadmium CTD PMID:16516943 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein more ... CTD PMID:16568437 more ... cadmium dichloride multiple interactions ISO Mapk8 (Mus musculus) 6480464 1 more ... CTD PMID:11958953 more ... cadmium dichloride increases response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 protein results in increased susceptibility to Cadmium Chloride CTD PMID:25374377 cadmium dichloride increases expression ISO MAPK8 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of MAPK8 protein modified form CTD PMID:24419708 cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:18021293 more ... cadmium dichloride increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Cadmium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:11958953 more ... cadmium dichloride increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Cadmium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:10874044 more ... cadmium dichloride increases activity EXP 6480464 Cadmium Chloride results in increased activity of MAPK8 protein CTD PMID:10637132 cadmium dichloride multiple interactions ISO MAPK8 (Homo sapiens) 6480464 1 more ... CTD PMID:21219922 more ... cadmium dichloride multiple interactions EXP 6480464 1 more ... CTD PMID:15618353 more ... cadmium selenide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [cadmium selenide co-treated with zinc sulfide] results in increased expression of MAPK8 mRNA CTD PMID:22342292 cadmium sulfate multiple interactions ISO Mapk8 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein] and cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:14687664 cadmium sulfate multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein] and Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:22767315 cadmium sulfate increases phosphorylation EXP 6480464 cadmium sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:22767315 Calcimycin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA and fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA] CTD PMID:21331654 calcipotriol decreases response to substance ISO Mapk8 (Mus musculus) 6480464 MAPK8 gene mutant form results in decreased susceptibility to calcipotriene CTD PMID:24046278 calcitriol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Calcitriol results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:12761878 camptothecin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Camptothecin results in increased phosphorylation of MAPK8 protein CTD PMID:30885713 and PMID:31255635 camptothecin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 MAPK8 protein affects the reaction [Camptothecin results in increased activity of SP1 protein] more ... CTD PMID:30885713 candesartan multiple interactions ISO Mapk8 (Mus musculus) 6480464 candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:20562518 cannabidiol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Cannabidiol results in increased phosphorylation of MAPK8 protein CTD PMID:32060308 cannabidiol multiple interactions ISO Mapk8 (Mus musculus) 6480464 Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA] and Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased phosphorylation of MAPK8 protein] CTD PMID:36988283 cannabidiol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA] and Cannabidiol inhibits the reaction [perfluorooctane sulfonic acid results in increased phosphorylation of MAPK8 protein] CTD PMID:36988283 cantharidic acid increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 cantharidic acid results in increased phosphorylation of MAPK8 protein CTD PMID:29345422 and PMID:31916385 capsaicin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 7-oxozeanol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:17292493 more ... capsaicin increases activity ISO MAPK8 (Homo sapiens) 6480464 Capsaicin results in increased activity of MAPK8 protein CTD PMID:12478662 more ... capsaicin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Capsaicin results in increased phosphorylation of MAPK8 protein CTD PMID:20619260 capsazepine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:22171160 captan increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Captan results in increased phosphorylation of MAPK8 protein CTD PMID:34303901 carbamazepine affects expression ISO MAPK8 (Homo sapiens) 6480464 Carbamazepine affects the expression of MAPK8 mRNA CTD PMID:24752500 carbendazim increases expression EXP 6480464 carbendazim results in increased expression of MAPK8 mRNA CTD PMID:35513110 carbon nanotube increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Nanotubes and Carbon results in increased phosphorylation of MAPK8 protein CTD PMID:32493873 carfilzomib increases expression EXP 6480464 carfilzomib results in increased expression of MAPK8 mRNA CTD PMID:27785949 carfilzomib multiple interactions EXP 6480464 apremilast inhibits the reaction [carfilzomib results in increased expression of MAPK8 mRNA] CTD PMID:27785949 carnosic acid multiple interactions EXP 6480464 salvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:25446857 carnosic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 salvin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein] CTD PMID:29854073 carnosine multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] and Carnosine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] CTD PMID:30802477 Carnosol multiple interactions ISO Mapk8 (Mus musculus) 6480464 carnosol inhibits the reaction [Dietary Fats results in increased expression of MAPK8 protein modified form] more ... CTD PMID:34678374 celecoxib multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Celecoxib inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of MAPK8 protein] CTD PMID:16442704 celecoxib multiple interactions ISO Mapk8 (Mus musculus) 6480464 Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein] CTD PMID:32416088 chalcone multiple interactions ISO Mapk8 (Mus musculus) 6480464 Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:22155221 chenodeoxycholic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 Chenodeoxycholic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] and Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25496033 chlordecone decreases expression ISO Mapk8 (Mus musculus) 6480464 Chlordecone results in decreased expression of MAPK8 mRNA CTD PMID:29980752 chlorogenic acid multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of MAPK8 protein] CTD PMID:34801538 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of MAPK8 mRNA CTD PMID:23125180 chloroquine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]] and Chloroquine promotes the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:31648047 chloroquine multiple interactions ISO Mapk8 (Mus musculus) 6480464 Chloroquine inhibits the reaction [lipopolysaccharide more ... CTD PMID:22341560 and PMID:28134560 chlorothalonil increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 tetrachloroisophthalonitrile results in increased phosphorylation of MAPK8 protein CTD PMID:34549778 chlorpromazine multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:23238562 chlorpyrifos increases phosphorylation EXP 6480464 Chlorpyrifos results in increased phosphorylation of MAPK8 protein CTD PMID:22714038 chlorpyrifos multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Chlorpyrifos co-treated with DEET co-treated with Pyridostigmine Bromide] results in increased phosphorylation of MAPK8 protein CTD PMID:34528356 cholate increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Cholates results in increased phosphorylation of MAPK8 protein CTD PMID:15750181 choline multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein and Tamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein] CTD PMID:23038002 chromium atom multiple interactions ISO Mapk8 (Mus musculus) 6480464 Chromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:21134603 chromium(6+) multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Arsenates co-treated with chromium hexavalent ion] results in increased expression of MAPK8 protein more ... CTD PMID:19654923 and PMID:19895865 chromium(6+) increases activity ISO MAPK8 (Homo sapiens) 6480464 chromium hexavalent ion results in increased activity of MAPK8 protein CTD PMID:12902192 chromium(6+) multiple interactions ISO MAPK8 (Homo sapiens) 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:12902192 chromium(6+) increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 chromium hexavalent ion results in increased phosphorylation of MAPK8 protein CTD PMID:19654923 and PMID:19895865 chromium(6+) increases expression ISO Mapk8 (Mus musculus) 6480464 chromium hexavalent ion results in increased expression of MAPK8 protein CTD PMID:19895865 chromium(6+) increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 chromium hexavalent ion results in increased phosphorylation of MAPK8 protein CTD PMID:17045426 chrysophanol affects phosphorylation ISO MAPK8 (Homo sapiens) 6480464 chrysophanic acid affects the phosphorylation of MAPK8 protein CTD PMID:30300626 cisplatin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Berberine co-treated with Cisplatin] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:11592233 more ... cisplatin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Cisplatin results in increased phosphorylation of MAPK8 protein CTD PMID:30550853 more ... cisplatin increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Cisplatin results in increased phosphorylation of MAPK8 protein CTD PMID:31153982 more ... cisplatin multiple interactions ISO Mapk8 (Mus musculus) 6480464 anemoside B4 inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:31153982 more ... cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of MAPK8 protein modified form CTD PMID:26739623 cisplatin multiple interactions EXP 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of MAPK8 protein modified form] and N-Acetylcysteinamide inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:15147517 and PMID:26739623 cisplatin increases phosphorylation EXP 6480464 Cisplatin results in increased phosphorylation of MAPK8 protein CTD PMID:15147517 cisplatin increases expression ISO Mapk8 (Mus musculus) 6480464 Cisplatin results in increased expression of MAPK8 mRNA CTD PMID:20883750 cobalt dichloride multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] and ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:24386346 cobalt dichloride increases phosphorylation EXP 6480464 cobaltous chloride results in increased phosphorylation of MAPK8 protein CTD PMID:21925238 more ... cobalt dichloride multiple interactions EXP 6480464 iodopravadoline inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] and Protein Kinase Inhibitors inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21925238 and PMID:31472278 cobalt dichloride increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 cobaltous chloride results in increased phosphorylation of MAPK8 protein CTD PMID:19101624 and PMID:24386346 cocaine multiple interactions ISO Mapk8 (Mus musculus) 6480464 acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:20354174 copper atom multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of MAPK8 mRNA more ... CTD PMID:16648635 more ... copper atom multiple interactions ISO Mapk8 (Mus musculus) 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:24690739 and PMID:30768131 copper atom multiple interactions EXP 6480464 [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein more ... CTD PMID:10941151 more ... copper(0) multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of MAPK8 mRNA more ... CTD PMID:16648635 more ... copper(0) multiple interactions ISO Mapk8 (Mus musculus) 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:24690739 and PMID:30768131 copper(0) multiple interactions EXP 6480464 [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein more ... CTD PMID:10941151 more ... copper(II) chloride multiple interactions EXP 6480464 [Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein more ... CTD PMID:11239917 and PMID:20920558 copper(II) chloride multiple interactions ISO Mapk8 (Mus musculus) 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein and pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein] CTD PMID:30768131 copper(II) sulfate increases expression ISO Mapk8 (Mus musculus) 6480464 Copper Sulfate results in increased expression of MAPK8 mRNA CTD PMID:33744278 copper(II) sulfate increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Copper Sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:33744278 cordycepin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 cordycepin results in increased phosphorylation of MAPK8 protein CTD PMID:28099944 and PMID:35732609 cordycepin affects expression ISO MAPK8 (Homo sapiens) 6480464 cordycepin affects the expression of MAPK8 mRNA CTD PMID:28099944 cordycepin increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 cordycepin results in increased phosphorylation of MAPK8 protein CTD PMID:28099944 cordycepin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [[cordycepin results in increased expression of CAV1 protein] which results in decreased expression of DUSP5 protein] which results in increased phosphorylation of MAPK8 protein more ... CTD PMID:19056796 more ... cordycepin multiple interactions EXP 6480464 cordycepin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:22366198 cordycepin multiple interactions ISO Mapk8 (Mus musculus) 6480464 cordycepin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:25342887 crocidolite asbestos increases expression ISO Mapk8 (Mus musculus) 6480464 Asbestos and Crocidolite results in increased expression of MAPK8 mRNA CTD PMID:19446018 crocidolite asbestos increases expression ISO MAPK8 (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of MAPK8 mRNA CTD PMID:25757056 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of MAPK8 mRNA CTD PMID:26577399 curcumin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK8 mRNA] more ... CTD PMID:18316600 more ... curcumin increases phosphorylation ISO MAPK8 (Homo sapiens) 150429751 Curcumin increases phosphorylation of MAPK8 protein in uterine cervix RGD curcumin decreases phosphorylation EXP 6480464 Curcumin results in decreased phosphorylation of MAPK8 protein CTD PMID:18332871 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11981161 more ... curcumin multiple interactions ISO Mapk8 (Mus musculus) 6480464 Curcumin inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16678799 more ... curcumin increases expression ISO MAPK8 (Homo sapiens) 6480464 Curcumin results in increased expression of MAPK8 mRNA CTD PMID:16101141 curcumin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Curcumin results in increased phosphorylation of MAPK8 protein CTD PMID:18316600 and PMID:34634291 cyclophosphamide increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Cyclophosphamide results in increased phosphorylation of MAPK8 protein CTD PMID:19696094 cyclophosphamide multiple interactions EXP 6480464 Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein and NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:19996110 cyclophosphamide multiple interactions ISO Mapk8 (Mus musculus) 6480464 GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:19696094 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of MAPK8 protein CTD PMID:10617104 cyclosporin A increases expression ISO MAPK8 (Homo sapiens) 6480464 Cyclosporine results in increased expression of MAPK8 mRNA CTD PMID:25562108 cypermethrin increases expression ISO MAPK8 (Homo sapiens) 6480464 cypermethrin results in increased expression of MAPK8 mRNA CTD PMID:27704156 cypermethrin multiple interactions EXP 6480464 [cypermethrin co-treated with pyrazolanthrone] results in decreased phosphorylation of MAPK8 protein more ... CTD PMID:34794910 and PMID:35512476 cypermethrin decreases phosphorylation EXP 6480464 cypermethrin results in decreased phosphorylation of MAPK8 protein CTD PMID:34794910 cypermethrin decreases phosphorylation ISO Mapk8 (Mus musculus) 6480464 cypermethrin results in decreased phosphorylation of MAPK8 protein CTD PMID:34794910 cypermethrin increases phosphorylation EXP 6480464 cypermethrin results in increased phosphorylation of MAPK8 protein CTD PMID:35512476 cypermethrin multiple interactions ISO Mapk8 (Mus musculus) 6480464 [[[cypermethrin results in decreased expression of MIR155 mRNA] which results in increased expression of BCL6 mRNA] which results in decreased expression of MAP2K4 protein] which results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:29471534 D-glucitol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Sorbitol results in increased phosphorylation of MAPK8 protein CTD PMID:24184208 D-glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:19861503 and PMID:34801538 D-glucose increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:36928891 D-glucose multiple interactions EXP 6480464 [[Paraquat results in increased phosphorylation of MAPK8 protein] which results in decreased abundance of Insulin] which results in increased abundance of Glucose more ... CTD PMID:34801538 and PMID:36394833 D-glucose multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Anisomycin inhibits the reaction [rutecarpine inhibits the reaction [Glucose results in increased phosphorylation of MAPK8 protein]] more ... CTD PMID:14505347 and PMID:36928891 D-mannitol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein] CTD PMID:10910949 DDT decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 DDT results in decreased phosphorylation of MAPK8 protein CTD PMID:14604893 decabromodiphenyl ether affects expression ISO MAPK8 (Homo sapiens) 6480464 decabromobiphenyl ether affects the expression of MAPK8 mRNA CTD PMID:24834073 delphinidin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 delphinidin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15740068 deoxynivalenol decreases activity ISO MAPK8 (Homo sapiens) 6480464 deoxynivalenol results in decreased activity of MAPK8 protein CTD PMID:20708668 deoxynivalenol increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 deoxynivalenol results in increased phosphorylation of MAPK8 protein CTD PMID:12377986 more ... deoxynivalenol multiple interactions ISO Mapk8 (Mus musculus) 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:14644621 more ... deoxynivalenol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein and deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:18485432 more ... Deoxyschizandrin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 schizandrin A inhibits the reaction [Mycophenolic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:35321622 desferrioxamine B increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Deferoxamine results in increased phosphorylation of MAPK8 protein CTD PMID:20368581 desferrioxamine B multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein] CTD PMID:20206247 desipramine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 1 more ... CTD PMID:18606486 dexamethasone multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein] and Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]] CTD PMID:10807665 dexamethasone affects expression ISO MAPK8 (Homo sapiens) 6480464 Dexamethasone affects the expression of MAPK8 mRNA CTD PMID:31181236 dexamethasone affects phosphorylation EXP 6480464 Dexamethasone affects the phosphorylation of MAPK8 protein CTD PMID:18234956 dexamethasone multiple interactions ISO Mapk8 (Mus musculus) 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:10874129 more ... Di-n-octyl phthalate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 di-n-octyl phthalate results in increased phosphorylation of MAPK8 protein CTD PMID:34822940 diallyl disulfide increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 diallyl disulfide results in increased phosphorylation of MAPK8 protein CTD PMID:14522920 diallyl disulfide multiple interactions ISO Mapk8 (Mus musculus) 6480464 diallyl disulfide inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:34896185 diallyl disulfide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 diallyl disulfide results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17647244 Diallyl sulfide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 allyl sulfide results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17647244 diallyl trisulfide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 diallyl trisulfide inhibits the reaction [TNF protein results in increased expression of MAPK8 mRNA] CTD PMID:34848446 Diallyltetrasulfane multiple interactions EXP 6480464 diallyl tetrasulfide inhibits the reaction [cypermethrin results in decreased phosphorylation of MAPK8 protein] CTD PMID:34794910 diarsenic trioxide affects response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 protein affects the susceptibility to Arsenic Trioxide CTD PMID:16818652 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of MAPK8 mRNA CTD PMID:34037972 diarsenic trioxide increases expression ISO Mapk8 (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of MAPK8 mRNA and Arsenic Trioxide results in increased expression of MAPK8 protein CTD PMID:34091186 diarsenic trioxide increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:15688020 diarsenic trioxide increases activity ISO MAPK8 (Homo sapiens) 6480464 Arsenic Trioxide results in increased activity of MAPK8 protein CTD PMID:11304686 more ... diarsenic trioxide increases response to substance ISO Mapk8 (Mus musculus) 6480464 MAPK8 protein results in increased susceptibility to Arsenic Trioxide and MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:16818652 diarsenic trioxide increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:18412143 more ... diarsenic trioxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21145380 more ... diarsenic trioxide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:14610070 more ... diarsenic trioxide increases response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:20799280 diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:21145380 more ... diarsenic trioxide increases expression ISO MAPK8 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of MAPK8 protein CTD PMID:17374990 diazepam multiple interactions EXP 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 diazinon increases expression EXP 6480464 Diazinon results in increased expression of MAPK8 mRNA CTD PMID:29108742 dibenziodolium multiple interactions ISO MAPK8 (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21391979 more ... dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of MAPK8 mRNA CTD PMID:21266533 diclofenac affects expression ISO MAPK8 (Homo sapiens) 6480464 Diclofenac affects the expression of MAPK8 mRNA CTD PMID:24752500 dicoumarol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein] and Dicumarol inhibits the reaction [Arsenic Trioxide results in increased activity of MAPK8 protein] CTD PMID:14701702 and PMID:24466103 dicrotophos decreases expression ISO MAPK8 (Homo sapiens) 6480464 dicrotophos results in decreased expression of MAPK8 mRNA CTD PMID:28302478 Dictamnine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 dictamnine inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MAPK8 protein] CTD PMID:30266538 diethyl maleate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [diethyl maleate results in increased expression of MAPK8 protein modified form] CTD PMID:30261343 diethyl maleate increases expression ISO MAPK8 (Homo sapiens) 6480464 diethyl maleate results in increased expression of MAPK8 protein modified form CTD PMID:30261343 diethyl phthalate multiple interactions ISO Mapk8 (Mus musculus) 6480464 diethyl phthalate results in increased expression of and results in increased phosphorylation of MAPK8 protein CTD PMID:37942807 diethylstilbestrol multiple interactions ISO Mapk8 (Mus musculus) 6480464 Diethylstilbestrol results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15171707 diltiazem decreases activity EXP 6480464 Diltiazem results in decreased activity of MAPK8 protein CTD PMID:11937779 dimethylarsinic acid increases expression ISO Mapk8 (Mus musculus) 6480464 Cacodylic Acid results in increased expression of MAPK8 mRNA CTD PMID:17441966 dimethylarsinic acid decreases expression EXP 6480464 Cacodylic Acid results in decreased expression of MAPK8 mRNA CTD PMID:17481689 Dinitramine increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 dinitramine results in increased phosphorylation of MAPK8 protein CTD PMID:33288293 dinophysistoxin 1 increases expression ISO MAPK8 (Homo sapiens) 6480464 dinophysistoxin 1 results in increased expression of MAPK8 mRNA CTD PMID:28939011 dioscin increases expression ISO MAPK8 (Homo sapiens) 6480464 dioscin results in increased expression of MAPK8 mRNA CTD PMID:29990575 diosmetin multiple interactions ISO Mapk8 (Mus musculus) 6480464 diosmetin inhibits the reaction [RANK Ligand results in increased phosphorylation of MAPK8 protein] CTD PMID:36563736 dioxygen multiple interactions ISO MAPK8 (Homo sapiens) 6480464 dictamnine inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10780954 more ... dioxygen increases activity ISO MAPK8 (Homo sapiens) 6480464 Oxygen deficiency results in increased activity of MAPK8 protein CTD PMID:10780954 and PMID:13679210 dioxygen increases phosphorylation EXP 6480464 Oxygen results in increased phosphorylation of MAPK8 protein CTD PMID:20812253 dioxygen multiple interactions EXP 6480464 2 more ... CTD PMID:12892836 and PMID:27274199 dioxygen increases activity EXP 6480464 Oxygen deficiency results in increased activity of MAPK8 protein CTD PMID:12892836 dioxygen increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Oxygen deficiency results in increased phosphorylation of MAPK8 protein CTD PMID:19196431 and PMID:30266538 diphenhydramine increases activity ISO MAPK8 (Homo sapiens) 6480464 Diphenhydramine results in increased activity of MAPK8 CTD PMID:17390763 dipyridamole increases activity ISO MAPK8 (Homo sapiens) 6480464 Dipyridamole results in increased activity of MAPK8 protein CTD PMID:11051267 disodium selenite multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:10644709 more ... disodium selenite increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Sodium Selenite results in increased phosphorylation of MAPK8 protein CTD PMID:34520753 disodium selenite multiple interactions ISO Mapk8 (Mus musculus) 6480464 Sodium Selenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein] and Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein] CTD PMID:18481333 and PMID:26522834 disodium selenite decreases expression ISO MAPK8 (Homo sapiens) 6480464 Sodium Selenite results in decreased expression of MAPK8 mRNA CTD PMID:18175754 disodium selenite decreases activity ISO MAPK8 (Homo sapiens) 6480464 Sodium Selenite results in decreased activity of MAPK8 protein CTD PMID:10644709 disulfiram multiple interactions EXP 6480464 [Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein and bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein] CTD PMID:11239917 disulfiram multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein CTD PMID:24690739 disulfiram multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein CTD PMID:24690739 donepezil hydrochloride multiple interactions EXP 6480464 Donepezil inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of MAPK8 protein] CTD PMID:19345205 dopamine multiple interactions ISO Mapk8 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein] and Glutathione inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:17481858 dopamine increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Dopamine results in increased phosphorylation of MAPK8 protein CTD PMID:17481858 dorsomorphin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 dorsomorphin multiple interactions ISO Mapk8 (Mus musculus) 6480464 dorsomorphin inhibits the reaction [pseudolaric acid B results in increased phosphorylation of MAPK8 protein] CTD PMID:37244295 dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [Resveratrol results in decreased expression of MAPK8 protein modified form] CTD PMID:27093858 doxorubicin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [DLJ14 compound co-treated with Doxorubicin] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:15494689 more ... doxorubicin decreases expression ISO MAPK8 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of MAPK8 mRNA CTD PMID:34719826 doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of MAPK8 protein CTD PMID:15623433 more ... doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of MAPK8 mRNA CTD PMID:26335259 doxorubicin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Doxorubicin results in increased phosphorylation of MAPK8 protein CTD PMID:15917298 more ... doxorubicin multiple interactions EXP 6480464 [Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in increased expression of MAPK8 mRNA] more ... CTD PMID:18346979 more ... doxorubicin increases response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 protein results in increased susceptibility to Doxorubicin CTD PMID:15917298 doxorubicin increases activity ISO MAPK8 (Homo sapiens) 6480464 Doxorubicin results in increased activity of MAPK8 protein CTD PMID:15880572 doxorubicin affects activity ISO MAPK8 (Homo sapiens) 6480464 Doxorubicin affects the activity of MAPK8 protein CTD PMID:15870702 edaravone increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Edaravone results in increased phosphorylation of MAPK8 protein CTD PMID:19954754 edaravone decreases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Edaravone results in decreased phosphorylation of MAPK8 protein CTD PMID:15824197 efavirenz multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein] and Acetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein] CTD PMID:21958719 efavirenz increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 efavirenz metabolite results in increased phosphorylation of MAPK8 protein and efavirenz results in increased phosphorylation of MAPK8 protein CTD PMID:21958719 elemental selenium decreases expression ISO Mapk8 (Mus musculus) 6480464 Selenium results in decreased expression of MAPK8 mRNA CTD PMID:28810182 elemental selenium multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Selenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:26187450 elemental selenium decreases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Selenium results in decreased phosphorylation of MAPK8 protein CTD PMID:17997286 ellagic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein CTD PMID:15735102 emetine multiple interactions ISO Mapk8 (Mus musculus) 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 and 4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK8 protein] CTD PMID:15772366 emetine increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Emetine results in increased phosphorylation of MAPK8 protein CTD PMID:15772366 enilconazole increases expression ISO MAPK8 (Homo sapiens) 6480464 enilconazole results in increased expression of MAPK8 mRNA CTD PMID:32201337 entinostat multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with entinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15964800 entinostat decreases expression ISO MAPK8 (Homo sapiens) 6480464 entinostat results in decreased expression of MAPK8 mRNA CTD PMID:27188386 epoxiconazole decreases expression ISO Mapk8 (Mus musculus) 6480464 epoxiconazole results in decreased expression of MAPK8 mRNA CTD PMID:35436446 erastin increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 erastin results in increased phosphorylation of MAPK8 protein CTD PMID:30817950 erastin multiple interactions ISO Mapk8 (Mus musculus) 6480464 GW 506033X inhibits the reaction [erastin results in increased phosphorylation of MAPK8 protein] CTD PMID:30817950 eriocitrin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [eriocitrin results in increased phosphorylation of MAPK8 protein] CTD PMID:34724282 eriocitrin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 eriocitrin results in increased phosphorylation of MAPK8 protein CTD PMID:34724282 eriodictyol multiple interactions ISO Mapk8 (Mus musculus) 6480464 eriodictyol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21544733 esculetin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [esculetin co-treated with Paclitaxel] results in increased expression of MAPK8 protein CTD PMID:16051289 esculetin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 esculetin results in increased phosphorylation of MAPK8 protein CTD PMID:19786087 esculetin increases expression ISO MAPK8 (Homo sapiens) 6480464 esculetin results in increased expression of MAPK8 protein CTD PMID:16051289 estragole increases phosphorylation EXP 6480464 estragole results in increased phosphorylation of MAPK8 protein CTD PMID:29054680 etacrynic acid decreases expression ISO MAPK8 (Homo sapiens) 6480464 Ethacrynic Acid results in decreased expression of MAPK8 protein CTD PMID:14556662 ethanol multiple interactions EXP 6480464 Polysaccharides inhibits the reaction [Ethanol results in increased phosphorylation of MAPK8 protein] CTD PMID:19735724 ethanol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 MAPK8 promotes the reaction [Ethanol results in increased expression of and results in increased activity of RUNX2 protein] CTD PMID:32198086 ethanol multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Bicuculline co-treated with Ethanol] results in increased expression of MAPK8 protein more ... CTD PMID:29044621 ethanol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Ethanol results in increased phosphorylation of MAPK8 protein CTD PMID:28062356 and PMID:32237978 ethanol increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Ethanol results in increased phosphorylation of MAPK8 protein CTD PMID:28119953 and PMID:29044621 ethanol increases phosphorylation EXP 6480464 Ethanol results in increased phosphorylation of MAPK8 protein CTD PMID:19735724 Ethyl pyruvate multiple interactions EXP 6480464 ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK8 protein] CTD PMID:21818760 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] and Egtazic Acid inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein] CTD PMID:11981161 and PMID:21544200 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] and Egtazic Acid inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:15254339 and PMID:21544200 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 Evodiamine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 1 more ... CTD PMID:23774672 Evodiamine increases expression ISO MAPK8 (Homo sapiens) 6480464 evodiamine results in increased expression of MAPK8 protein modified form CTD PMID:23774672 farnesyl diphosphate multiple interactions ISO Mapk8 (Mus musculus) 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 febuxostat increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Febuxostat results in increased phosphorylation of MAPK8 protein CTD PMID:35866629 fenvalerate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 fenvalerate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein] CTD PMID:28949029 ferroheme b increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Heme results in increased phosphorylation of MAPK8 protein CTD PMID:36115635 ferroheme b multiple interactions ISO Mapk8 (Mus musculus) 6480464 LY96 protein promotes the reaction [Heme results in increased phosphorylation of MAPK8 protein] CTD PMID:36115635 ferrosoferric oxide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Ferrosoferric Oxide binds to titanium dioxide] which results in increased phosphorylation of MAPK8 protein CTD PMID:30098274 ferulic acid decreases activity EXP 6480464 ferulic acid results in decreased activity of MAPK8 protein CTD PMID:15363954 ferulic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21291945 flubendazole increases activity ISO MAPK8 (Homo sapiens) 6480464 flubendazole results in increased activity of MAPK8 protein CTD PMID:32652169 flufenoxuron increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 flufenoxuron results in increased phosphorylation of MAPK8 protein CTD PMID:33771252 flufenoxuron multiple interactions ISO Mapk8 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [flufenoxuron results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:33771252 fluorescein 5-isothiocyanate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein] and Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 fluorescein 5-isothiocyanate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 fluoxetine decreases expression EXP 6480464 Fluoxetine results in decreased expression of MAPK8 mRNA CTD PMID:20924750 flutamide increases expression EXP 6480464 Flutamide results in increased expression of MAPK8 mRNA CTD PMID:24136188 folic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 [pyrazolanthrone co-treated with 6 more ... CTD PMID:21528358 more ... folic acid decreases expression ISO Mapk8 (Mus musculus) 6480464 Folic Acid results in decreased expression of MAPK8 mRNA CTD PMID:25629700 folic acid increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Folic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:31447676 fomepizole multiple interactions ISO Mapk8 (Mus musculus) 6480464 Fomepizole inhibits the reaction [Acetaminophen results in increased phosphorylation of and affects the localization of MAPK8 protein] CTD PMID:29739258 and PMID:30903181 fomepizole affects binding ISO Mapk8 (Mus musculus) 6480464 Fomepizole binds to MAPK8 protein CTD PMID:30903181 formononetin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 formononetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:34077701 formoterol fumarate multiple interactions EXP 6480464 [Formoterol Fumarate co-treated with desisobutyrylciclesonide] inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein] and Formoterol Fumarate inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein] CTD PMID:26003274 fructose increases expression EXP 6480464 Fructose results in increased expression of MAPK8 protein CTD PMID:29430716 fructose multiple interactions EXP 6480464 imoxin inhibits the reaction [Fructose results in increased expression of MAPK8 protein] CTD PMID:29430716 fucoxanthin multiple interactions ISO Mapk8 (Mus musculus) 6480464 fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:35616142 Fulvic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA] and fulvic acid inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK8 protein] CTD PMID:21331654 and PMID:25888188 furan multiple interactions ISO Mapk8 (Mus musculus) 6480464 rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK8 protein] CTD PMID:34450210 furan increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 furan results in increased phosphorylation of MAPK8 protein CTD PMID:34450210 galactose increases expression EXP 6480464 Galactose results in increased expression of MAPK8 mRNA CTD PMID:35259467 galactose multiple interactions EXP 6480464 Galactose promotes the reaction [sodium arsenite results in increased expression of MAPK8 mRNA] CTD PMID:35259467 galangin multiple interactions EXP 6480464 galangin inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein] CTD PMID:35843304 gallic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] CTD PMID:21420233 gamma-aminobutyric acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased expression of MAPK8 protein] CTD PMID:29044621 gamma-hexachlorocyclohexane multiple interactions EXP 6480464 Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:23927878 Gastrodin multiple interactions EXP 6480464 gastrodin inhibits the reaction [4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased phosphorylation of MAPK8 protein] CTD PMID:30790395 gefitinib increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 gefitinib results in increased phosphorylation of MAPK8 protein CTD PMID:20846305 gefitinib multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Gefitinib inhibits the reaction [tetrachlorodian results in increased expression of MAPK8 mRNA] CTD PMID:36190352 gefitinib decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Gefitinib results in decreased phosphorylation of MAPK8 protein CTD PMID:35317323 Geniposide pentaacetate multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK8 protein] CTD PMID:17651887 Geniposide pentaacetate increases phosphorylation EXP 6480464 pentaacetyl geniposide results in increased phosphorylation of MAPK8 protein CTD PMID:17651887 gentamycin multiple interactions EXP 6480464 CAT protein inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:15936777 more ... gentamycin increases activity EXP 6480464 Gentamicins results in increased activity of MAPK8 protein CTD PMID:20074632 gentamycin increases phosphorylation EXP 6480464 Gentamicins results in increased phosphorylation of MAPK8 protein CTD PMID:16401625 geraniol multiple interactions EXP 6480464 geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK8 mRNA] and geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:35608392 ginkgolide B multiple interactions ISO MAPK8 (Homo sapiens) 6480464 ginkgolide B inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:19464278 ginsenoside Rg1 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:24386346 gliclazide multiple interactions EXP 6480464 Gliclazide inhibits the reaction [Acetic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:32045587 gliotoxin multiple interactions EXP 6480464 Gliotoxin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17466404 glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:19861503 and PMID:34801538 glucose increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:36928891 glucose multiple interactions EXP 6480464 [[Paraquat results in increased phosphorylation of MAPK8 protein] which results in decreased abundance of Insulin] which results in increased abundance of Glucose more ... CTD PMID:34801538 and PMID:36394833 glucose multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Anisomycin inhibits the reaction [rutecarpine inhibits the reaction [Glucose results in increased phosphorylation of MAPK8 protein]] more ... CTD PMID:14505347 and PMID:36928891 glutathione multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Glutathione deficiency promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein] CTD PMID:16112521 glutathione multiple interactions EXP 6480464 Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:22767315 glutathione multiple interactions ISO Mapk8 (Mus musculus) 6480464 Glutathione inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein] and Glutathione inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:17481858 and PMID:20423716 glycidyl methacrylate increases expression ISO MAPK8 (Homo sapiens) 6480464 glycidyl methacrylate results in increased expression of MAPK8 protein CTD PMID:36641056 glycochenodeoxycholic acid increases phosphorylation EXP 6480464 Glycochenodeoxycholic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:34979142 glycochenodeoxycholic acid multiple interactions EXP 6480464 7-hydroxycoumarin inhibits the reaction [Glycochenodeoxycholic Acid results in increased phosphorylation of MAPK8 protein] and Scopoletin inhibits the reaction [Glycochenodeoxycholic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:34979142 glyphosate increases expression ISO MAPK8 (Homo sapiens) 6480464 Glyphosate results in increased expression of MAPK8 mRNA CTD PMID:31874349 Goe 6976 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Go 6976 inhibits the reaction [[cholix toxin and Vibrio cholerae co-treated with TNF protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:28087840 guggulsterone increases activity ISO MAPK8 (Homo sapiens) 6480464 pregna-4 more ... CTD PMID:17475222 GW 4064 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:25496033 GW 4064 increases expression ISO Mapk8 (Mus musculus) 6480464 GW 4064 results in increased expression of MAPK8 mRNA CTD PMID:26655953 GW 4064 multiple interactions ISO Mapk8 (Mus musculus) 6480464 GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] and GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25496033 haloperidol increases phosphorylation EXP 6480464 Haloperidol results in increased phosphorylation of MAPK8 protein CTD PMID:17092607 heme b multiple interactions ISO Mapk8 (Mus musculus) 6480464 LY96 protein promotes the reaction [Heme results in increased phosphorylation of MAPK8 protein] CTD PMID:36115635 heme b increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Heme results in increased phosphorylation of MAPK8 protein CTD PMID:36115635 hemin multiple interactions EXP 6480464 Hemin promotes the reaction [Paraquat results in increased phosphorylation of MAPK8 protein] CTD PMID:19080378 hesperetin multiple interactions ISO Mapk8 (Mus musculus) 6480464 hesperetin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:31153982 hesperetin multiple interactions EXP 6480464 hesperetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:19222219 hesperetin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Cisplatin co-treated with hesperetin] results in decreased phosphorylation of MAPK8 protein CTD PMID:31153982 hesperidin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Hesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK8 protein] CTD PMID:19110045 hexachlorobenzene increases phosphorylation EXP 6480464 Hexachlorobenzene results in increased phosphorylation of MAPK8 protein CTD PMID:23708402 hexadecanoic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:21745629 hexadecanoic acid increases phosphorylation EXP 6480464 Palmitic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:34979142 hexadecanoic acid increases expression EXP 6480464 Palmitic Acid results in increased expression of MAPK8 mRNA CTD PMID:30259999 hexadecanoic acid multiple interactions EXP 6480464 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]] more ... CTD PMID:25109277 more ... hexadecanoic acid increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Palmitic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:21134603 and PMID:34678374 hexadecanoic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 carnosol inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21134603 and PMID:34678374 hexadecanoic acid increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Palmitic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:21745629 hexaflumuron increases expression EXP 6480464 hexafluoron results in increased expression of MAPK8 mRNA CTD PMID:34993831 and PMID:35773501 hexamethylene diisocyanate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 1 and 6-hexamethylene diisocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 hexamethylene diisocyanate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 1 and 6-hexamethylene diisocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 histamine multiple interactions EXP 6480464 Histamine inhibits the reaction [decamethrin results in decreased nitrosation of MAPK8 protein] CTD PMID:25299849 homocysteine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Homocysteine results in increased phosphorylation of MAPK8 protein CTD PMID:25888188 homocysteine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 fulvic acid inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK8 protein] CTD PMID:25888188 Honokiol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 honokiol results in increased phosphorylation of MAPK8 protein CTD PMID:33550458 hydrogen peroxide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10910949 more ... hydrogen peroxide increases expression ISO MAPK8 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of MAPK8 mRNA CTD PMID:31521693 hydrogen peroxide increases phosphorylation EXP 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein CTD PMID:16284289 more ... hydrogen peroxide increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein CTD PMID:15064094 more ... hydrogen peroxide increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein CTD PMID:10910949 more ... hydrogen peroxide increases activity ISO MAPK8 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased activity of MAPK8 protein CTD PMID:12215205 and PMID:12902192 hydrogen peroxide affects expression ISO MAPK8 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of MAPK8 protein CTD PMID:21179406 hydrogen peroxide increases activity ISO Mapk8 (Mus musculus) 6480464 Hydrogen Peroxide results in increased activity of MAPK8 protein CTD PMID:10843682 more ... hydrogen peroxide increases activity EXP 6480464 Hydrogen Peroxide results in increased activity of MAPK8 protein CTD PMID:15574683 hydrogen peroxide multiple interactions EXP 6480464 2-(4-((dimethylamino)methyl)benzylidene)-5 more ... CTD PMID:11562448 more ... hydrogen peroxide multiple interactions ISO Mapk8 (Mus musculus) 6480464 Chenodeoxycholic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10843682 more ... hydroquinone increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 hydroquinone results in increased phosphorylation of MAPK8 protein CTD PMID:23791922 hydroquinone multiple interactions ISO MAPK8 (Homo sapiens) 6480464 hydroquinone results in decreased expression of and results in increased phosphorylation of MAPK8 protein CTD PMID:37148176 hydroquinone O-beta-D-glucopyranoside decreases expression ISO MAPK8 (Homo sapiens) 6480464 Arbutin results in decreased expression of MAPK8 mRNA CTD PMID:17103032 hydroxyurea decreases phosphorylation EXP 6480464 Hydroxyurea results in decreased phosphorylation of MAPK8 protein CTD PMID:15557822 hymexazol increases expression EXP 6480464 hymexazol results in increased expression of MAPK8 mRNA CTD PMID:35773501 hypochlorous acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:18156441 ibuprofen increases expression ISO Mapk8 (Mus musculus) 6480464 Ibuprofen results in increased expression of MAPK8 mRNA CTD PMID:37453669 icatibant multiple interactions EXP 6480464 icatibant inhibits the reaction [KLK1 protein inhibits the reaction [Gentamicins results in increased phosphorylation of MAPK8 protein]] CTD PMID:16401625 ifosfamide increases activity EXP 6480464 Ifosfamide results in increased activity of MAPK8 protein CTD PMID:31722249 ifosfamide multiple interactions EXP 6480464 morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein] CTD PMID:31722249 imidacloprid increases expression EXP 6480464 imidacloprid results in increased expression of MAPK8 mRNA CTD PMID:34993831 indoxyl sulfate multiple interactions ISO Mapk8 (Mus musculus) 6480464 Indican results in increased expression of and results in increased phosphorylation of MAPK8 protein CTD PMID:30849338 indoxyl sulfate increases phosphorylation EXP 6480464 Indican results in increased phosphorylation of MAPK8 protein CTD PMID:32045570 insulin multiple interactions EXP 6480464 [[Paraquat results in increased phosphorylation of MAPK8 protein] which results in decreased abundance of Insulin] which results in increased abundance of Glucose CTD PMID:36394833 iomeprol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 iomeprol results in increased phosphorylation of MAPK8 protein CTD PMID:21036957 ionomycin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein and Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein] CTD PMID:25073960 iron atom multiple interactions EXP 6480464 [teferrol results in increased abundance of Iron] which results in increased phosphorylation of MAPK8 protein CTD PMID:35307918 iron(0) multiple interactions EXP 6480464 [teferrol results in increased abundance of Iron] which results in increased phosphorylation of MAPK8 protein CTD PMID:35307918 Isoliensinine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 isoliensinine results in increased phosphorylation of MAPK8 protein CTD PMID:26219228 Isoliensinine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [isoliensinine results in increased phosphorylation of MAPK8 protein] CTD PMID:26219228 isoprenaline multiple interactions ISO Mapk8 (Mus musculus) 6480464 candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:20562518 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of MAPK8 mRNA CTD PMID:35608392 isoprenaline increases activity EXP 6480464 Isoproterenol results in increased activity of MAPK8 protein CTD PMID:10591028 isoprenaline multiple interactions EXP 6480464 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:15951400 and PMID:35608392 isoprenaline increases phosphorylation EXP 6480464 Isoproterenol results in increased phosphorylation of MAPK8 protein CTD PMID:15951400 and PMID:35608392 isoprenaline increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Isoproterenol results in increased phosphorylation of MAPK8 protein CTD PMID:20562518 isorhamnetin multiple interactions EXP 6480464 3-methylquercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:19222219 Isorhapontigenin multiple interactions EXP 6480464 isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein] CTD PMID:15607907 ivermectin multiple interactions ISO Mapk8 (Mus musculus) 6480464 Ivermectin inhibits the reaction [lipopolysaccharide and E coli O55-B5 results in increased phosphorylation of MAPK8 protein] CTD PMID:19168156 ivermectin decreases expression ISO MAPK8 (Homo sapiens) 6480464 Ivermectin results in decreased expression of MAPK8 protein CTD PMID:32959892 kaempferol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 kaempferol results in increased phosphorylation of MAPK8 protein CTD PMID:30499162 kanamycin A increases phosphorylation EXP 6480464 Kanamycin results in increased phosphorylation of MAPK8 protein CTD PMID:17570507 ketoconazole increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Ketoconazole results in increased phosphorylation of MAPK8 protein CTD PMID:19631732 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of MAPK8 mRNA CTD PMID:25787151 KN-93 multiple interactions EXP 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21933187 kojic acid decreases expression ISO MAPK8 (Homo sapiens) 6480464 kojic acid results in decreased expression of MAPK8 mRNA CTD PMID:16595896 KT 5823 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 KT 5823 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:35122928 L-1,4-dithiothreitol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein] CTD PMID:10644709 L-ascorbic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:20206247 and PMID:24488945 L-cysteine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK8 protein and MAPK8 mutant form results in decreased susceptibility to [sodium arsenite co-treated with Cysteine deficiency co-treated with Methionine deficiency] CTD PMID:11312036 and PMID:11709198 L-gamma-glutamyl-L-cysteine multiple interactions EXP 6480464 gamma-glutamylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein] CTD PMID:34767868 L-glutamic acid multiple interactions EXP 6480464 shikonin inhibits the reaction [Glutamic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:35028790 L-glutamic acid increases phosphorylation EXP 6480464 Glutamic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:35028790 L-methionine increases activity ISO MAPK8 (Homo sapiens) 6480464 Methionine deficiency results in increased activity of MAPK8 protein CTD PMID:11880182 L-methionine multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein and Tamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein] CTD PMID:23038002 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK8 protein and MAPK8 mutant form results in decreased susceptibility to [sodium arsenite co-treated with Cysteine deficiency co-treated with Methionine deficiency] CTD PMID:11312036 and PMID:11709198 lactacystin increases activity ISO Mapk8 (Mus musculus) 6480464 lactacystin results in increased activity of MAPK8 protein CTD PMID:15618349 lactacystin increases phosphorylation EXP 6480464 lactacystin results in increased phosphorylation of MAPK8 protein CTD PMID:18463101 lactacystin increases activity EXP 6480464 lactacystin results in increased activity of MAPK8 protein CTD PMID:15618349 lactulose multiple interactions EXP 6480464 Lactulose inhibits the reaction [Thioacetamide results in increased expression of MAPK8 protein] CTD PMID:35961375 lead diacetate multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:20829427 more ... lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of MAPK8 mRNA CTD PMID:37471654 lead diacetate affects expression EXP 6480464 lead acetate affects the expression of MAPK8 CTD PMID:24293362 lead diacetate increases phosphorylation EXP 6480464 lead acetate results in increased phosphorylation of MAPK8 protein CTD PMID:25088297 lead(0) multiple interactions EXP 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of MAPK8 protein CTD PMID:35307918 lead(II) chloride increases expression ISO MAPK8 (Homo sapiens) 6480464 lead chloride results in increased expression of MAPK8 protein modified form CTD PMID:24419708 lenvatinib increases expression EXP 6480464 lenvatinib results in increased expression of MAPK8 mRNA CTD PMID:34019861 leupeptin multiple interactions ISO Mapk8 (Mus musculus) 6480464 leupeptin promotes the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein] CTD PMID:33458793 Licochalcone A multiple interactions ISO MAPK8 (Homo sapiens) 6480464 licochalcone A promotes the reaction [Sorafenib results in decreased phosphorylation of MAPK8 protein] and Sorafenib promotes the reaction [licochalcone A results in decreased phosphorylation of MAPK8 protein] CTD PMID:30187994 Licochalcone A increases expression ISO MAPK8 (Homo sapiens) 6480464 licochalcone A results in increased expression of MAPK8 mRNA CTD PMID:30055311 Licochalcone A decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 licochalcone A results in decreased phosphorylation of MAPK8 protein CTD PMID:30187994 Licochalcone B multiple interactions ISO Mapk8 (Mus musculus) 6480464 licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:25451593 Licochalcone B increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 licochalcone B results in increased phosphorylation of MAPK8 protein CTD PMID:35948134 linsidomine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 bosutinib affects the reaction [linsidomine results in increased phosphorylation of MAPK8 protein] CTD PMID:34519134 linsidomine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 linsidomine results in increased phosphorylation of MAPK8 protein CTD PMID:34519134 lipoic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA CTD PMID:23830814 lipopolysaccharide increases phosphorylation ISO MAPK8 (Homo sapiens) 150429951 lipopolysaccharide increases phosphorylation of MAPK8 protein in the pulmonary alveolus epithelium RGD lipopolysaccharide increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Lipopolysaccharides results in increased phosphorylation of MAPK8 protein CTD PMID:20307528 more ... lipopolysaccharide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 1 more ... CTD PMID:17698565 more ... lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of MAPK8 protein CTD PMID:16934299 more ... lipopolysaccharide multiple interactions EXP 6480464 Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16934299 more ... lipopolysaccharide increases expression ISO Mapk8 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of MAPK8 protein modified form CTD PMID:15832817 lipopolysaccharide multiple interactions ISO Mapk8 (Mus musculus) 6480464 2'-hydroxyflavanone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11123339 more ... lipopolysaccharide increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Lipopolysaccharides results in increased phosphorylation of MAPK8 protein CTD PMID:11123339 more ... lipoteichoic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein and TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein] CTD PMID:23238562 lithium atom increases expression EXP 6480464 Lithium results in increased expression of MAPK8 protein CTD PMID:18296634 lithium atom increases phosphorylation EXP 6480464 Lithium results in increased phosphorylation of MAPK8 protein CTD PMID:18296634 lithium hydride increases phosphorylation EXP 6480464 Lithium results in increased phosphorylation of MAPK8 protein CTD PMID:18296634 lithium hydride increases expression EXP 6480464 Lithium results in increased expression of MAPK8 protein CTD PMID:18296634 Longikaurin A increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 longikaurin A results in increased phosphorylation of MAPK8 protein CTD PMID:28801140 Longikaurin A multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK8 protein] CTD PMID:28801140 loperamide decreases expression ISO MAPK8 (Homo sapiens) 6480464 Loperamide results in decreased expression of MAPK8 mRNA CTD PMID:34719826 loperamide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Loperamide promotes the reaction [Doxorubicin results in decreased expression of MAPK8 mRNA] CTD PMID:34719826 lovastatin multiple interactions EXP 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of MAPK8 protein modified form] CTD PMID:26739623 luteolin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10718847 more ... luteolin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Luteolin results in increased phosphorylation of MAPK8 protein CTD PMID:21601631 LY294002 multiple interactions ISO Mapk8 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [flufenoxuron results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11306679 more ... LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16018989 LY294002 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21420390 and PMID:26385185 lycopene decreases expression ISO MAPK8 (Homo sapiens) 6480464 lycopene results in decreased expression of MAPK8 protein CTD PMID:17337101 Maduramicin increases phosphorylation EXP 6480464 maduramicin results in increased phosphorylation of MAPK8 protein CTD PMID:31229567 Maduramicin increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 maduramicin results in increased phosphorylation of MAPK8 protein CTD PMID:31229567 Maduramicin multiple interactions ISO Mapk8 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [maduramicin results in increased phosphorylation of MAPK8 protein] and PPP5C protein inhibits the reaction [maduramicin results in increased phosphorylation of MAPK8 protein] CTD PMID:31229567 Magnolol multiple interactions ISO Mapk8 (Mus musculus) 6480464 magnolol inhibits the reaction [trimethyltin results in increased phosphorylation of MAPK8 protein] CTD PMID:26756313 malonaldehyde multiple interactions EXP 6480464 MAPK8 protein promotes the reaction [Malondialdehyde results in increased expression of COL1A2 mRNA] CTD PMID:11295527 Malonoben multiple interactions ISO MAPK8 (Homo sapiens) 6480464 tyrphostin A9 inhibits the reaction [S100A4 protein results in increased phosphorylation of MAPK8 protein] CTD PMID:16948116 maneb multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in increased expression of MAPK8 mRNA CTD PMID:36117858 manganese atom increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Manganese results in increased phosphorylation of MAPK8 protein CTD PMID:17045426 manganese atom multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein and pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein] CTD PMID:30951808 and PMID:32574669 manganese(0) increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Manganese results in increased phosphorylation of MAPK8 protein CTD PMID:17045426 manganese(0) multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein and pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein] CTD PMID:30951808 and PMID:32574669 manganese(II) chloride increases activity ISO MAPK8 (Homo sapiens) 6480464 manganese chloride results in increased activity of MAPK8 protein CTD PMID:20152896 manganese(II) chloride increases methylation ISO MAPK8 (Homo sapiens) 6480464 manganese chloride results in increased methylation of MAPK8 gene CTD PMID:27913844 manganese(II) chloride multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein and pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein] CTD PMID:30951808 and PMID:32574669 manganese(II) chloride increases phosphorylation EXP 6480464 manganese chloride results in increased phosphorylation of MAPK8 protein CTD PMID:24324973 manganese(II) chloride increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 manganese chloride results in increased phosphorylation of MAPK8 protein CTD PMID:19084589 and PMID:20152896 mangiferin decreases expression ISO Mapk8 (Mus musculus) 6480464 mangiferin results in decreased expression of MAPK8 mRNA CTD PMID:15135318 manumycin A multiple interactions ISO Mapk8 (Mus musculus) 6480464 manumycin inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:19739265 marimastat multiple interactions EXP 6480464 marimastat inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein] CTD PMID:15574683 masoprocol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of MAPK8 protein modified form] CTD PMID:17395008 mebendazole increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Mebendazole results in increased phosphorylation of MAPK8 protein CTD PMID:20848085 Mecamylamine multiple interactions EXP 6480464 Mecamylamine inhibits the reaction [Potassium deficiency results in increased phosphorylation of MAPK8 protein] CTD PMID:18222492 mechlorethamine increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Mechlorethamine results in increased phosphorylation of MAPK8 protein CTD PMID:25891025 melatonin increases expression ISO MAPK8 (Homo sapiens) 6480464 Melatonin results in increased expression of MAPK8 protein CTD PMID:19012662 menadione multiple interactions EXP 6480464 Vitamin K 3 results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:19386027 menadione increases activity ISO MAPK8 (Homo sapiens) 6480464 Vitamin K 3 results in increased activity of MAPK8 protein CTD PMID:12215205 menadione affects response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 protein affects the susceptibility to Vitamin K 3 CTD PMID:12215205 menadione increases phosphorylation EXP 6480464 Vitamin K 3 results in increased phosphorylation of MAPK8 protein CTD PMID:16310883 mercaptoethanol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Mercaptoethanol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein] CTD PMID:10644709 mercury dichloride increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Mercuric Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:10861847 more ... Mesna multiple interactions ISO Mapk8 (Mus musculus) 6480464 Mesna inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:19696094 metam multiple interactions ISO Mapk8 (Mus musculus) 6480464 methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:15933225 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [Glucose results in increased phosphorylation of MAPK8 protein] CTD PMID:34801538 metformin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Metformin inhibits the reaction [INS protein results in increased expression of MAPK8 protein] CTD PMID:36764371 methamphetamine increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Methamphetamine results in increased phosphorylation of MAPK8 protein CTD PMID:32768653 methidathion decreases expression ISO Mapk8 (Mus musculus) 6480464 methidathion results in decreased expression of MAPK8 mRNA CTD PMID:34813904 methotrexate increases phosphorylation EXP 6480464 Methotrexate results in increased phosphorylation of MAPK8 protein CTD PMID:20885979 methotrexate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 MAPK8 gene mutant form inhibits the reaction [Methotrexate results in increased expression of CDKN1A protein] CTD PMID:22183962 methoxychlor increases expression ISO Mapk8 (Mus musculus) 6480464 Methoxychlor results in increased expression of MAPK8 mRNA CTD PMID:20829426 methylglyoxal multiple interactions ISO MAPK8 (Homo sapiens) 6480464 sulforaphane inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK8 protein] CTD PMID:25933243 methylglyoxal increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Pyruvaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:31103701 methylglyoxal multiple interactions ISO Mapk8 (Mus musculus) 6480464 MAPK8 protein affects the reaction [Pyruvaldehyde results in increased expression of ACP5 mRNA] more ... CTD PMID:31103701 methylglyoxal increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Pyruvaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:25933243 methylmercury chloride increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 methylmercuric chloride results in increased phosphorylation of MAPK8 protein CTD PMID:27667695 methylmercury chloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:36813253 methylmercury chloride increases phosphorylation EXP 6480464 methylmercuric chloride results in increased phosphorylation of MAPK8 protein CTD PMID:36813253 methylphenidate increases expression ISO Mapk8 (Mus musculus) 6480464 Methylphenidate results in increased expression of MAPK8 mRNA CTD PMID:22470460 methylseleninic acid increases expression ISO MAPK8 (Homo sapiens) 6480464 methylselenic acid results in increased expression of MAPK8 mRNA CTD PMID:12517777 miconazole increases expression EXP 6480464 Miconazole results in increased expression of MAPK8 mRNA CTD PMID:22262564 microcystin-LR multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK8 protein CTD PMID:29984889 mifepristone multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]] CTD PMID:10807665 minocycline decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Minocycline results in decreased phosphorylation of MAPK8 protein CTD PMID:17872917 mitomycin C multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Mitomycin results in increased activity of and results in increased phosphorylation of MAPK8 protein CTD PMID:16186332 ML-7 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [ML 7 co-treated with quinocetone] results in increased phosphorylation of MAPK8 protein CTD PMID:26446980 mono(2-ethylhexyl) phthalate affects phosphorylation ISO MAPK8 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate affects the phosphorylation of MAPK8 protein CTD PMID:30810372 monodansylcadaverine multiple interactions ISO Mapk8 (Mus musculus) 6480464 monodansylcadaverine inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:22341560 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of MAPK8 mRNA CTD PMID:28954212 morin multiple interactions EXP 6480464 morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein] CTD PMID:31722249 muscimol multiple interactions ISO Mapk8 (Mus musculus) 6480464 Muscimol inhibits the reaction [Ethanol results in increased expression of MAPK8 protein] CTD PMID:29044621 mycophenolic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] and schizandrin A inhibits the reaction [Mycophenolic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:20302854 and PMID:35321622 mycophenolic acid increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Mycophenolic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:35321622 mycophenolic acid decreases expression EXP 6480464 Mycophenolic Acid results in decreased expression of MAPK8 protein modified form CTD PMID:20302854 myricitrin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 N(6),N(6)-dimethyladenine multiple interactions EXP 6480464 N(6) and N(6)-dimethyladenine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15618353 N,N-diethyl-m-toluamide multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Chlorpyrifos co-treated with DEET co-treated with Pyridostigmine Bromide] results in increased phosphorylation of MAPK8 protein CTD PMID:34528356 N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide multiple interactions EXP 6480464 Tiapride Hydrochloride inhibits the reaction [4-iodo-2 and 5-dimethoxyphenylisopropylamine results in increased phosphorylation of MAPK8 protein] CTD PMID:30790395 N-acetyl-L-cysteine multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK8 protein]] more ... CTD PMID:10397638 more ... N-acetyl-L-cysteine multiple interactions ISO MAPK8 (Homo sapiens) 150429751 N-acetyl-L-cysteine inhibits the reaction [Curcumin increases phosphorylation of MAPK8 protein in uterine cervix] RGD N-acetyl-L-cysteine decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine results in decreased phosphorylation of MAPK8 protein CTD PMID:24735948 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:17041759 more ... N-acetyl-L-cysteine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:12684028 more ... N-acetylsphingosine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 N-acetylsphingosine promotes the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein] CTD PMID:33959992 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases phosphorylation EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:18463101 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases response to substance ISO Mapk8 (Mus musculus) 6480464 MAPK8 gene mutant form results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde CTD PMID:23593480 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Mapk8 (Mus musculus) 6480464 MAPK8 affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA] CTD PMID:23593480 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein and nordy inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:17377739 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions EXP 6480464 MAPK8 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Reactive Oxygen Species] and N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17560994 N-methyl-4-phenylpyridinium increases activity ISO Mapk8 (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein CTD PMID:11181820 N-methyl-4-phenylpyridinium increases expression ISO MAPK8 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of MAPK8 mRNA CTD PMID:25234470 N-methyl-4-phenylpyridinium increases activity ISO MAPK8 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein CTD PMID:17240529 N-methyl-4-phenylpyridinium multiple interactions ISO MAPK8 (Homo sapiens) 6480464 RNF7 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein] CTD PMID:17240529 N-methyl-N'-nitro-N-nitrosoguanidine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Methylnitronitrosoguanidine results in increased phosphorylation of MAPK8 protein CTD PMID:22001597 N-methyl-N-nitrosourea multiple interactions ISO Mapk8 (Mus musculus) 6480464 Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein] and MAPK8 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein] CTD PMID:18593901 N-methyl-N-nitrosourea increases phosphorylation EXP 6480464 Methylnitrosourea results in increased phosphorylation of MAPK8 protein CTD PMID:16168987 N-methyl-N-nitrosourea increases activity EXP 6480464 Methylnitrosourea results in increased activity of MAPK8 protein CTD PMID:18593901 N-methyl-N-nitrosourea multiple interactions EXP 6480464 Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein] more ... CTD PMID:12693035 more ... N-methyl-N-nitrosourea increases activity ISO Mapk8 (Mus musculus) 6480464 Methylnitrosourea results in increased activity of MAPK8 protein CTD PMID:18593901 N-methyl-N-nitrosourea decreases response to substance ISO Mapk8 (Mus musculus) 6480464 MAPK8 gene mutant form results in decreased susceptibility to Methylnitrosourea CTD PMID:18593901 N-Nitroso-N-methylurethane multiple interactions EXP 6480464 Nitrosomethylurethane results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:12693035 N-nitrosodiethylamine multiple interactions ISO Mapk8 (Mus musculus) 6480464 Butylated Hydroxyanisole inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein] more ... CTD PMID:15989949 more ... N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA and [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK8 mRNA CTD PMID:23830814 N-nitrosodiethylamine increases response to substance ISO Mapk8 (Mus musculus) 6480464 MAPK8 protein results in increased susceptibility to Diethylnitrosamine and MAPK8 results in increased susceptibility to Diethylnitrosamine CTD PMID:16807293 and PMID:25496033 N-nitrosodiethylamine increases activity ISO Mapk8 (Mus musculus) 6480464 Diethylnitrosamine results in increased activity of MAPK8 protein CTD PMID:15989949 and PMID:18691550 N-nitrosodimethylamine multiple interactions EXP 6480464 Dimethylnitrosamine results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:12971962 Narciclasine multiple interactions ISO Mapk8 (Mus musculus) 6480464 narciclasine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:30738987 naringin multiple interactions ISO Mapk8 (Mus musculus) 6480464 naringin inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein] CTD PMID:22198281 neocuproine multiple interactions EXP 6480464 [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein more ... CTD PMID:18056745 nerolidol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 nerolidol results in increased expression of and results in increased phosphorylation of MAPK8 mRNA CTD PMID:35357761 nickel dichloride multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21843586 nickel dichloride multiple interactions ISO Mapk8 (Mus musculus) 6480464 MAPK8 affects the reaction [nickel chloride results in increased expression of PTGS2 mRNA] and MAPK8 affects the reaction [nickel chloride results in increased expression of PTGS2 protein] CTD PMID:17065197 nickel dichloride increases phosphorylation EXP 6480464 nickel chloride results in increased phosphorylation of MAPK8 protein CTD PMID:21843586 nickel sulfate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein] and SB 203580 promotes the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:18495191 nickel sulfate increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 nickel sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:18467339 nickel sulfate multiple interactions ISO Mapk8 (Mus musculus) 6480464 MAP3K1 protein affects the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:18467339 nickel sulfate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 nickel sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:15588916 more ... niclosamide multiple interactions ISO Mapk8 (Mus musculus) 6480464 Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:28824321 nicotinamide multiple interactions EXP 6480464 Niacinamide inhibits the reaction [Methylnitrosourea results in increased phosphorylation of MAPK8 protein] CTD PMID:16168987 nicotine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11592233 and PMID:20727180 nicotine increases activity EXP 6480464 Nicotine results in increased activity of MAPK8 protein CTD PMID:17021677 nicotine increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:21511693 nicotine multiple interactions EXP 6480464 Nicotine promotes the reaction [MAPK8 protein results in increased phosphorylation of JUN protein] CTD PMID:17021677 nicotine increases expression EXP 6480464 Nicotine results in increased expression of MAPK8 mRNA CTD PMID:20426880 nicotine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:20727180 nitroprusside decreases expression EXP 6480464 Nitroprusside results in decreased expression of MAPK8 protein modified form CTD PMID:20132804 nitroprusside affects response to substance EXP 6480464 MAPK8 protein affects the susceptibility to Nitroprusside CTD PMID:20132804 nitroprusside multiple interactions EXP 6480464 MAPK8 protein affects the susceptibility to [Nitroprusside results in decreased expression of BCL2L1 mRNA] CTD PMID:20132804 nocodazole multiple interactions ISO MAPK8 (Homo sapiens) 6480464 TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK8 protein] CTD PMID:12221076 nocodazole increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Nocodazole results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 NORCANTHARIDIN increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 norcantharidin results in increased phosphorylation of MAPK8 protein CTD PMID:21266192 and PMID:29193574 notoginsenoside R1 multiple interactions EXP 6480464 notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK8 protein] CTD PMID:24975829 ochratoxin A multiple interactions EXP 6480464 ochratoxin A results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17651772 ochratoxin A increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 ochratoxin A results in increased phosphorylation of MAPK8 protein CTD PMID:31154016 okadaic acid increases expression ISO MAPK8 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of MAPK8 mRNA CTD PMID:28939011 oleanolic acid decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Oleanolic Acid analog results in decreased phosphorylation of MAPK8 protein CTD PMID:26612655 olmesartan decreases activity ISO Mapk8 (Mus musculus) 6480464 olmesartan results in decreased activity of MAPK8 protein CTD PMID:17208988 olmesartan decreases expression ISO Mapk8 (Mus musculus) 6480464 olmesartan results in decreased expression of MAPK8 protein modified form CTD PMID:17208988 oltipraz multiple interactions ISO MAPK8 (Homo sapiens) 6480464 oltipraz inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein] CTD PMID:33959992 osthole increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 osthol results in increased phosphorylation of MAPK8 protein CTD PMID:29319219 oxidopamine increases phosphorylation EXP 6480464 Oxidopamine results in increased phosphorylation of MAPK8 protein CTD PMID:25446857 oxidopamine multiple interactions EXP 6480464 salvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:25446857 oxidopamine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 puag-haad inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18675900 and PMID:31176653 oxidopamine multiple interactions ISO Mapk8 (Mus musculus) 6480464 2-chloro-5-hydroxyphenylglycine affects the reaction [[GOPC protein affects the susceptibility to Oxidopamine] which affects the phosphorylation of MAPK8 protein] more ... CTD PMID:10397638 and PMID:33571554 oxidopamine increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Oxidopamine results in increased phosphorylation of MAPK8 protein CTD PMID:33571554 oxidopamine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Oxidopamine results in increased phosphorylation of MAPK8 protein CTD PMID:18675900 and PMID:31176653 ozone increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Ozone results in increased phosphorylation of MAPK8 protein CTD PMID:19536146 ozone multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of MAPK8 mRNA CTD PMID:27106289 p-menthan-3-ol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Menthol results in increased phosphorylation of MAPK8 protein CTD PMID:18955132 paclitaxel increases activity ISO MAPK8 (Homo sapiens) 6480464 Paclitaxel results in increased activity of MAPK8 protein CTD PMID:11160861 paclitaxel increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Paclitaxel results in increased phosphorylation of MAPK8 protein CTD PMID:19426673 paclitaxel increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Paclitaxel results in increased phosphorylation of MAPK8 protein CTD PMID:11123339 paclitaxel multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [esculetin co-treated with Paclitaxel] results in increased expression of MAPK8 protein more ... CTD PMID:10075725 more ... paclitaxel multiple interactions ISO Mapk8 (Mus musculus) 6480464 CD14 protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK8 protein] and ITGAM protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK8 protein] CTD PMID:11123339 paclitaxel increases expression ISO MAPK8 (Homo sapiens) 6480464 Paclitaxel results in increased expression of MAPK8 protein CTD PMID:16051289 paracetamol multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Acetaminophen co-treated with Carbon Tetrachloride] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:17185352 more ... paracetamol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Acetaminophen results in increased phosphorylation of MAPK8 protein CTD PMID:33959992 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of MAPK8 mRNA CTD PMID:33387578 paracetamol increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Acetaminophen results in increased phosphorylation of MAPK8 protein CTD PMID:19931551 more ... paracetamol decreases expression ISO MAPK8 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of MAPK8 mRNA CTD PMID:27761495 paracetamol increases expression ISO MAPK8 (Homo sapiens) 6480464 Acetaminophen results in increased expression of MAPK8 mRNA CTD PMID:20732408 and PMID:27761495 paracetamol increases response to substance EXP 6480464 MAPK8 results in increased susceptibility to Acetaminophen CTD PMID:11562448 paracetamol multiple interactions EXP 6480464 Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein and MAP2K4 mutant form inhibits the reaction [Acetaminophen results in increased activity of MAPK8 protein] CTD PMID:11562448 paracetamol increases response to substance ISO Mapk8 (Mus musculus) 6480464 MAPK8 protein results in increased susceptibility to Acetaminophen CTD PMID:18700144 paracetamol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetaminophen results in increased phosphorylation of and affects the activity of MAPK8 protein more ... CTD PMID:17185352 and PMID:33959992 paraquat multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Paraquat results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16687388 more ... paraquat multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in increased expression of MAPK8 mRNA CTD PMID:36117858 paraquat increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Paraquat results in increased phosphorylation of MAPK8 protein CTD PMID:28474156 paraquat increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Paraquat results in increased phosphorylation of MAPK8 protein CTD PMID:28215578 paraquat increases phosphorylation EXP 6480464 Paraquat results in increased phosphorylation of MAPK8 protein CTD PMID:16687388 more ... paraquat multiple interactions ISO MAPK8 (Homo sapiens) 6480464 MAPK8 protein affects the reaction [Paraquat results in increased expression of MUC5AC mRNA] more ... CTD PMID:17018646 more ... parecoxib increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 parecoxib results in increased phosphorylation of MAPK8 protein CTD PMID:35917206 paroxetine increases activity EXP 6480464 Paroxetine results in increased activity of MAPK8 protein CTD PMID:17728140 paroxetine multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Paroxetine results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:17728140 parthenolide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 parthenolide results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16921510 parthenolide multiple interactions EXP 6480464 parthenolide inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA] CTD PMID:30259999 parthenolide increases expression ISO MAPK8 (Homo sapiens) 6480464 parthenolide results in increased expression of MAPK8 mRNA CTD PMID:16921510 patulin increases phosphorylation EXP 6480464 Patulin results in increased phosphorylation of MAPK8 protein CTD PMID:34896196 PD 168393 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 PD168393 inhibits the reaction [2 more ... CTD PMID:16778083 pentanal decreases expression ISO MAPK8 (Homo sapiens) 6480464 pentanal results in decreased expression of MAPK8 mRNA CTD PMID:26079696 Pentoxifylline increases expression ISO MAPK8 (Homo sapiens) 6480464 Pentoxifylline results in increased expression of MAPK8 protein and Pentoxifylline results in increased expression of MAPK8 protein modified form CTD PMID:20804743 peptidoglycan increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Peptidoglycan results in increased phosphorylation of MAPK8 protein CTD PMID:21647617 perfluorooctane-1-sulfonic acid decreases phosphorylation EXP 6480464 perfluorooctane sulfonic acid results in decreased phosphorylation of MAPK8 protein CTD PMID:28973641 perfluorooctane-1-sulfonic acid increases expression ISO MAPK8 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA CTD PMID:36988283 perfluorooctane-1-sulfonic acid increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in increased phosphorylation of MAPK8 protein CTD PMID:36988283 perfluorooctane-1-sulfonic acid increases expression ISO Mapk8 (Mus musculus) 6480464 perfluorooctane sulfonic acid results in increased expression of MAPK8 mRNA CTD PMID:36988283 perfluorooctane-1-sulfonic acid increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 perfluorooctane sulfonic acid results in increased phosphorylation of MAPK8 protein CTD PMID:36988283 perfluorooctane-1-sulfonic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MAPK8 mRNA more ... CTD PMID:36331819 and PMID:36988283 perfluorooctane-1-sulfonic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [perfluorooctane sulfonic acid results in increased phosphorylation of and results in increased activity of MAPK8 protein] which affects the localization of BAX protein more ... CTD PMID:34006824 and PMID:36988283 perfluorooctanoic acid increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 perfluorooctanoic acid results in increased phosphorylation of MAPK8 protein CTD PMID:37044272 perifosine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [perifosine co-treated with Butyrates] results in increased activity of MAPK8 protein more ... CTD PMID:15781658 phenobarbital affects expression ISO MAPK8 (Homo sapiens) 6480464 Phenobarbital affects the expression of MAPK8 mRNA CTD PMID:19159669 phenylephrine multiple interactions EXP 6480464 GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:16385079 more ... phenylephrine increases phosphorylation EXP 6480464 Phenylephrine results in increased phosphorylation of MAPK8 protein CTD PMID:10727428 and PMID:16385079 phloretin multiple interactions EXP 6480464 Phloretin inhibits the reaction [Arsenic Trioxide results in increased expression of MAPK8 mRNA] CTD PMID:34037972 phorbol 13-acetate 12-myristate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:14610070 more ... phorbol 13-acetate 12-myristate increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein CTD PMID:20172950 more ... phorbol 13-acetate 12-myristate multiple interactions ISO Mapk8 (Mus musculus) 6480464 Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] and GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25496033 phorbol 13-acetate 12-myristate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein CTD PMID:16838270 more ... phorone multiple interactions ISO Mapk8 (Mus musculus) 6480464 [phorone co-treated with tert-Butylhydroperoxide] results in increased phosphorylation of MAPK8 protein CTD PMID:20423716 phosgene increases phosphorylation EXP 6480464 Phosgene results in increased phosphorylation of MAPK8 protein CTD PMID:21818760 phosgene multiple interactions EXP 6480464 ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK8 protein] CTD PMID:21818760 phthalic anhydride multiple interactions ISO MAPK8 (Homo sapiens) 6480464 phthalic anhydride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 phthalic anhydride increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 phthalic anhydride results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 pifithrin-? multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pifithrin inhibits the reaction [Silybin results in increased phosphorylation of MAPK8 protein] CTD PMID:16777994 pifithrin-? increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 pifithrin results in increased phosphorylation of MAPK8 protein CTD PMID:16061640 pipoxolan multiple interactions ISO Mapk8 (Mus musculus) 6480464 pipoxolan inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:32677756 pirfenidone multiple interactions ISO Mapk8 (Mus musculus) 6480464 pirfenidone inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein] CTD PMID:34890640 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of MAPK8 mRNA CTD PMID:12832660 pirinixic acid increases expression ISO Mapk8 (Mus musculus) 6480464 pirinixic acid results in increased expression of MAPK8 mRNA CTD PMID:17426115 and PMID:18301758 platycodin D increases activity ISO MAPK8 (Homo sapiens) 6480464 platycodin D results in increased activity of MAPK8 protein CTD PMID:20412017 plitidepsin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 AKT1 protein affects the reaction [plitidepsin results in increased activity of MAPK8 protein] CTD PMID:18089842 plitidepsin increases activity ISO MAPK8 (Homo sapiens) 6480464 plitidepsin results in increased activity of MAPK8 protein CTD PMID:18089842 potassium atom multiple interactions EXP 6480464 Mecamylamine inhibits the reaction [Potassium deficiency results in increased phosphorylation of MAPK8 protein] CTD PMID:18222492 potassium atom increases phosphorylation EXP 6480464 Potassium deficiency results in increased phosphorylation of MAPK8 protein CTD PMID:18222492 potassium chromate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10910949 potassium chromate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 potassium chromate(VI) results in increased phosphorylation of MAPK8 protein CTD PMID:10910949 pramipexole multiple interactions EXP 6480464 pramipexole inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:16362428 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of MAPK8 mRNA CTD PMID:19162173 proanthocyanidin multiple interactions EXP 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25088297 procyanidin B3 multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Lipopolysaccharides co-treated with procyanidin B3] results in decreased phosphorylation of MAPK8 protein more ... CTD PMID:22169119 procymidone increases expression ISO Mapk8 (Mus musculus) 6480464 procymidone results in increased expression of MAPK8 mRNA CTD PMID:35913088 prodigiosin decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Prodigiosin results in decreased phosphorylation of MAPK8 protein CTD PMID:31077745 progesterone multiple interactions EXP 6480464 Progesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:16284289 prostaglandin E2 increases activity ISO Mapk8 (Mus musculus) 6480464 Dinoprostone results in increased activity of MAPK8 protein CTD PMID:16644903 prostaglandin E2 multiple interactions ISO Mapk8 (Mus musculus) 6480464 L-826266 inhibits the reaction [Dinoprostone results in increased activity of MAPK8 protein] CTD PMID:16644903 prostaglandin F2alpha increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Dinoprost results in increased phosphorylation of MAPK8 protein CTD PMID:24333336 prostaglandin F2alpha multiple interactions ISO Mapk8 (Mus musculus) 6480464 resveratrol inhibits the reaction [Dinoprost results in increased phosphorylation of MAPK8 protein] and SRT1720 inhibits the reaction [Dinoprost results in increased phosphorylation of MAPK8 protein] CTD PMID:24333336 protein kinase inhibitor multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Protein Kinase Inhibitors inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein] CTD PMID:26385185 protein kinase inhibitor multiple interactions EXP 6480464 Protein Kinase Inhibitors inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21925238 Pseudolaric acid B multiple interactions ISO Mapk8 (Mus musculus) 6480464 dorsomorphin inhibits the reaction [pseudolaric acid B results in increased phosphorylation of MAPK8 protein] and pyrazolanthrone inhibits the reaction [pseudolaric acid B results in increased phosphorylation of MAPK8 protein] CTD PMID:37244295 Pseudolaric acid B increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 pseudolaric acid B results in increased phosphorylation of MAPK8 protein CTD PMID:37244295 psoralen increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Ficusin results in increased phosphorylation of MAPK8 protein CTD PMID:31364909 psoralen multiple interactions ISO MAPK8 (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased phosphorylation of MAPK8 protein] CTD PMID:31364909 pterostilbene multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] and pterostilbene results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:19447859 and PMID:24154491 puerarin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 arsenic trioxide promotes the reaction [puerarin results in increased expression of MAPK8 protein] CTD PMID:20416161 puerarin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 puerarin results in increased phosphorylation of MAPK8 protein CTD PMID:21884717 puerarin increases expression ISO MAPK8 (Homo sapiens) 6480464 puerarin results in increased expression of MAPK8 protein CTD PMID:20416161 Pyridostigmine bromide multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Chlorpyrifos co-treated with DEET co-treated with Pyridostigmine Bromide] results in increased phosphorylation of MAPK8 protein CTD PMID:34528356 pyrrolidine dithiocarbamate multiple interactions EXP 6480464 [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:10941151 more ... pyrrolidine dithiocarbamate increases activity EXP 6480464 pyrrolidine dithiocarbamic acid results in increased activity of MAPK8 protein CTD PMID:10658192 quercetin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Quercetin results in increased phosphorylation of MAPK8 protein CTD PMID:18377872 more ... quercetin increases expression ISO MAPK8 (Homo sapiens) 6480464 Quercetin results in increased expression of MAPK8 mRNA and Quercetin results in increased expression of MAPK8 protein modified form CTD PMID:19017364 and PMID:23727915 quercetin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:10718847 more ... quinoline multiple interactions ISO MAPK8 (Homo sapiens) 6480464 quinoline analog inhibits the reaction [MAP3K20 protein promotes the reaction [Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein]] and quinoline analog results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:15737997 ramipril multiple interactions EXP 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] and Ramipril inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] CTD PMID:31062909 razoxane affects activity ISO MAPK8 (Homo sapiens) 6480464 Razoxane affects the activity of MAPK8 CTD PMID:10487526 reactive oxygen species multiple interactions EXP 6480464 MAPK8 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Reactive Oxygen Species] CTD PMID:17560994 reactive oxygen species multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK8 protein]] and [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]] CTD PMID:35833596 reactive oxygen species multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [[Bortezomib co-treated with Butyrates] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15173093 more ... resiniferatoxin increases activity ISO MAPK8 (Homo sapiens) 6480464 resiniferatoxin results in increased activity of MAPK8 protein CTD PMID:9580328 resveratrol multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Resveratrol results in increased activity of MAPK8 protein] which results in increased phosphorylation of and results in increased activity of TRP53 protein more ... CTD PMID:11933078 more ... resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of MAPK8 protein modified form CTD PMID:27093858 resveratrol multiple interactions EXP 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:27093858 more ... resveratrol affects response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 protein affects the susceptibility to resveratrol CTD PMID:20082299 resveratrol multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of MAPK8 mRNA more ... CTD PMID:15217905 more ... resveratrol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 resveratrol results in increased phosphorylation of MAPK8 protein CTD PMID:18347188 resveratrol decreases expression ISO MAPK8 (Homo sapiens) 6480464 resveratrol results in decreased expression of MAPK8 protein CTD PMID:18089832 resveratrol increases activity ISO Mapk8 (Mus musculus) 6480464 resveratrol results in increased activity of MAPK8 protein CTD PMID:11933078 and PMID:21679764 resveratrol decreases activity ISO MAPK8 (Homo sapiens) 6480464 resveratrol results in decreased activity of MAPK8 protein CTD PMID:11408617 resveratrol decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 resveratrol results in decreased phosphorylation of MAPK8 protein CTD PMID:23437203 rifampicin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]] and Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:31648047 rimonabant multiple interactions ISO Mapk8 (Mus musculus) 6480464 Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1 more ... CTD PMID:18950629 Ro 31-8220 multiple interactions EXP 6480464 Ro 31-8220 inhibits the reaction [Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein] CTD PMID:11756236 rosmarinic acid decreases phosphorylation EXP 6480464 Rosmarinic Acid results in decreased phosphorylation of MAPK8 protein CTD PMID:28789951 rotenone increases activity ISO MAPK8 (Homo sapiens) 6480464 Rotenone results in increased activity of MAPK8 protein CTD PMID:10780954 rotenone increases expression ISO MAPK8 (Homo sapiens) 6480464 Rotenone results in increased expression of MAPK8 mRNA CTD PMID:32368861 rotenone increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Rotenone results in increased phosphorylation of MAPK8 protein CTD PMID:31648047 and PMID:32368861 rotenone multiple interactions EXP 6480464 1-(1-acetyl-piperidine-4-yl)-3-adamantan-1-yl-urea inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:30472438 rotenone increases phosphorylation EXP 6480464 Rotenone results in increased phosphorylation of MAPK8 protein CTD PMID:30472438 rotenone multiple interactions ISO Mapk8 (Mus musculus) 6480464 Rotenone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:29906494 rotenone increases activity ISO Mapk8 (Mus musculus) 6480464 Rotenone results in increased activity of MAPK8 protein CTD PMID:11181820 rotenone multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]] more ... CTD PMID:10780954 more ... rottlerin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 rottlerin inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein] and rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:15917298 and PMID:20599481 Rutecarpine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Anisomycin inhibits the reaction [rutecarpine inhibits the reaction [Glucose results in increased phosphorylation of MAPK8 protein]] and rutecarpine inhibits the reaction [Glucose results in increased phosphorylation of MAPK8 protein] CTD PMID:36928891 rutin multiple interactions ISO Mapk8 (Mus musculus) 6480464 Rutin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:35304134 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein more ... CTD PMID:14701702 and PMID:16112521 Salidroside multiple interactions ISO Mapk8 (Mus musculus) 6480464 rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK8 protein] CTD PMID:34450210 salubrinal multiple interactions EXP 6480464 [salubrinal results in increased expression of EIF2S1 protein modified form] which results in increased phosphorylation of MAPK8 protein CTD PMID:21147958 salubrinal multiple interactions ISO MAPK8 (Homo sapiens) 6480464 salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein] and salubrinal inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:20686688 and PMID:21809093 Salvianolic acid A multiple interactions ISO Mapk8 (Mus musculus) 6480464 salvianolic acid A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:31654708 sanguinarine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [sanguinarine results in increased phosphorylation of MAPK8 protein] CTD PMID:19135517 sanguinarine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 sanguinarine results in increased phosphorylation of MAPK8 protein CTD PMID:19135517 sappanchalcone increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 sappanchalcone results in increased phosphorylation of MAPK8 protein CTD PMID:21963806 SB 203580 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 SB 203580 inhibits the reaction [4-vinyl-2 more ... CTD PMID:13679210 more ... SB 203580 increases phosphorylation EXP 6480464 SB 203580 results in increased phosphorylation of MAPK8 protein CTD PMID:28087833 SB 203580 decreases activity ISO MAPK8 (Homo sapiens) 6480464 SB 203580 results in decreased activity of MAPK8 protein CTD PMID:18089842 SB 203580 multiple interactions EXP 6480464 SB 203580 promotes the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] CTD PMID:12487375 SB 431542 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SCH772984 multiple interactions EXP 6480464 SCH772984 inhibits the reaction [diphenylarsinic acid results in increased phosphorylation of MAPK8 protein] CTD PMID:28087833 SCH772984 decreases expression EXP 6480464 SCH772984 results in decreased expression of MAPK8 protein CTD PMID:28087833 scopoletin multiple interactions EXP 6480464 Scopoletin inhibits the reaction [Glycochenodeoxycholic Acid results in increased phosphorylation of MAPK8 protein] and Scopoletin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:34979142 selenium atom decreases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Selenium results in decreased phosphorylation of MAPK8 protein CTD PMID:17997286 selenium atom multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Selenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:26187450 selenium atom decreases expression ISO Mapk8 (Mus musculus) 6480464 Selenium results in decreased expression of MAPK8 mRNA CTD PMID:28810182 selenomethionine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Selenomethionine inhibits the reaction [Spermine results in increased activity of MAPK8 protein] CTD PMID:20121705 serpentine asbestos multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Asbestos and Serpentine results in increased phosphorylation of MAPK8 protein] CTD PMID:24735948 serpentine asbestos increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Asbestos and Serpentine results in increased phosphorylation of MAPK8 protein CTD PMID:15882436 and PMID:24735948 sertraline multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein] and Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17728140 Shikonin multiple interactions EXP 6480464 shikonin inhibits the reaction [Glutamic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:35028790 silibinin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Silybin results in increased phosphorylation of MAPK8 protein CTD PMID:16777994 silibinin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pifithrin inhibits the reaction [Silybin results in increased phosphorylation of MAPK8 protein] and pyrazolanthrone inhibits the reaction [Silybin results in increased phosphorylation of MAPK8 protein] CTD PMID:16777994 silicon dioxide decreases expression ISO Mapk8 (Mus musculus) 6480464 Silicon Dioxide results in decreased expression of MAPK8 mRNA CTD PMID:19073995 silicon dioxide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of MAPK8 protein] and pyrazolanthrone inhibits the reaction [Silicon Dioxide results in increased phosphorylation of MAPK8 protein] CTD PMID:35689653 silicon dioxide increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased phosphorylation of MAPK8 protein and Silicon Dioxide results in increased phosphorylation of MAPK8 protein CTD PMID:24844442 more ... silicon dioxide increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Silicon Dioxide results in increased phosphorylation of MAPK8 protein CTD PMID:27616297 silver atom affects expression ISO MAPK8 (Homo sapiens) 6480464 Silver affects the expression of MAPK8 mRNA CTD PMID:22342292 silver atom increases phosphorylation EXP 6480464 Silver results in increased phosphorylation of MAPK8 protein CTD PMID:26702581 silver(0) affects expression ISO MAPK8 (Homo sapiens) 6480464 Silver affects the expression of MAPK8 mRNA CTD PMID:22342292 silver(0) increases phosphorylation EXP 6480464 Silver results in increased phosphorylation of MAPK8 protein CTD PMID:26702581 simvastatin multiple interactions ISO Mapk8 (Mus musculus) 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] and Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein] CTD PMID:18310456 simvastatin increases activity ISO Mapk8 (Mus musculus) 6480464 Simvastatin results in increased activity of MAPK8 protein CTD PMID:15187114 simvastatin multiple interactions EXP 6480464 Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:18047562 sinapic acid multiple interactions EXP 6480464 sinapinic acid inhibits the reaction [lead acetate results in increased expression of MAPK8 mRNA] CTD PMID:37471654 sirolimus multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [7-hydroxystaurosporine co-treated with Sirolimus] results in increased phosphorylation of MAPK8 protein and pyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased phosphorylation of MAPK8 protein] CTD PMID:15767555 sodium arsenate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 sodium arsenate results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 sodium arsenite multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21642427 more ... sodium arsenite decreases expression ISO MAPK8 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of MAPK8 mRNA CTD PMID:29301061 sodium arsenite decreases expression ISO Mapk8 (Mus musculus) 6480464 sodium arsenite results in decreased expression of MAPK8 mRNA CTD PMID:31233874 sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:11408547 more ... sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of MAPK8 mRNA and sodium arsenite results in increased expression of MAPK8 protein CTD PMID:24497207 more ... sodium arsenite increases activity EXP 6480464 sodium arsenite results in increased activity of MAPK8 protein CTD PMID:17658681 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of MAPK8 protein CTD PMID:19072884 sodium arsenite multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11312036 more ... sodium arsenite increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 sodium arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:16973625 more ... sodium arsenite increases expression ISO Mapk8 (Mus musculus) 6480464 sodium arsenite results in increased expression of MAPK8 mRNA more ... CTD PMID:19822182 more ... sodium arsenite multiple interactions ISO Mapk8 (Mus musculus) 6480464 [MAPK8 protein mutant form results in decreased phosphorylation of and results in decreased activity of MAPK8 protein] inhibits the reaction [sodium arsenite promotes the reaction [CPEB4 protein binds to SORBS3 protein]] more ... CTD PMID:16973625 more ... sodium arsenite increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 sodium arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:12482858 more ... sodium arsenite increases expression ISO MAPK8 (Homo sapiens) 6480464 sodium arsenite results in increased expression of MAPK8 protein modified form CTD PMID:23219847 sodium arsenite increases activity ISO MAPK8 (Homo sapiens) 6480464 sodium arsenite results in increased activity of MAPK8 protein CTD PMID:22706169 and PMID:23219847 sodium arsenite increases response to substance ISO MAPK8 (Homo sapiens) 6480464 MAPK8 protein results in increased susceptibility to sodium arsenite CTD PMID:21726611 sodium dichromate affects expression EXP 6480464 sodium bichromate affects the expression of MAPK8 mRNA CTD PMID:11960910 sodium fluoride multiple interactions EXP 6480464 [IL1RN protein co-treated with Sodium Fluoride] results in increased phosphorylation of MAPK8 protein and Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of MAPK8 mRNA] CTD PMID:30633982 and PMID:35172196 sodium fluoride increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Sodium Fluoride results in increased phosphorylation of MAPK8 protein CTD PMID:26862884 sodium fluoride increases expression ISO Mapk8 (Mus musculus) 6480464 Sodium Fluoride results in increased expression of MAPK8 mRNA CTD PMID:32156525 sodium fluoride multiple interactions ISO Mapk8 (Mus musculus) 6480464 PTH protein promotes the reaction [Sodium Fluoride results in increased expression of MAPK8 mRNA] CTD PMID:32156525 sodium fluoride increases phosphorylation EXP 6480464 Sodium Fluoride results in increased phosphorylation of MAPK8 protein CTD PMID:35172196 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of MAPK8 mRNA CTD PMID:30633982 Soman increases phosphorylation EXP 6480464 Soman results in increased phosphorylation of MAPK8 protein CTD PMID:21971501 Soman multiple interactions EXP 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 sorafenib multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Bortezomib co-treated with Sorafenib] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:16985072 and PMID:30187994 sorafenib decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Sorafenib results in decreased phosphorylation of MAPK8 protein CTD PMID:30187994 spermine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Spermine results in increased activity of MAPK8 protein] and Selenomethionine inhibits the reaction [Spermine results in increased activity of MAPK8 protein] CTD PMID:20121705 spermine increases activity ISO MAPK8 (Homo sapiens) 6480464 Spermine results in increased activity of MAPK8 protein CTD PMID:20121705 SR 144528 multiple interactions ISO Mapk8 (Mus musculus) 6480464 SR 144528 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK8 protein] CTD PMID:24184660 stavudine decreases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Stavudine results in decreased phosphorylation of MAPK8 protein CTD PMID:27041070 streptozocin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein] CTD PMID:25541468 streptozocin multiple interactions EXP 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:31062909 streptozocin increases phosphorylation EXP 6480464 Streptozocin results in increased phosphorylation of MAPK8 protein CTD PMID:31062909 streptozocin increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Streptozocin results in increased phosphorylation of MAPK8 protein CTD PMID:30802477 streptozocin multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:26522834 more ... succimer multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of MAPK8 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of MAPK8 mRNA CTD PMID:21641980 and PMID:26378955 sucrose multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Oligosaccharides inhibits the reaction [[Sucrose co-treated with Dietary Fats] affects the expression of MAPK8 mRNA] CTD PMID:31181236 sulforaphane increases activity ISO MAPK8 (Homo sapiens) 6480464 sulforaphane results in increased activity of MAPK8 protein CTD PMID:16201852 sulforaphane multiple interactions ISO MAPK8 (Homo sapiens) 6480464 sulforaphane inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:25933243 and PMID:32387680 sulindac multiple interactions ISO MAPK8 (Homo sapiens) 6480464 CDKN1A protein promotes the reaction [Sulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:15713900 more ... sulindac increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Sulindac results in increased phosphorylation of MAPK8 protein CTD PMID:17292881 sulindac increases expression ISO Mapk8 (Mus musculus) 6480464 Sulindac results in increased expression of MAPK8 mRNA CTD PMID:17292881 sulindac sulfide increases activity ISO MAPK8 (Homo sapiens) 6480464 sulindac sulfide results in increased activity of MAPK8 protein CTD PMID:11051267 sulindac sulfone increases activity ISO MAPK8 (Homo sapiens) 6480464 sulindac sulfone results in increased activity of MAPK8 protein CTD PMID:11051267 more ... sunitinib increases expression ISO MAPK8 (Homo sapiens) 6480464 Sunitinib results in increased expression of MAPK8 mRNA CTD PMID:31533062 superoxide increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Superoxides results in increased phosphorylation of MAPK8 protein CTD PMID:33290831 surfactin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 surfactin peptide results in increased phosphorylation of MAPK8 protein CTD PMID:34850538 surfactin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [surfactin peptide results in increased phosphorylation of MAPK8 protein] and KIRA6 inhibits the reaction [surfactin peptide results in increased phosphorylation of MAPK8 protein] CTD PMID:34850538 surfactin C increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 surfactin peptide results in increased phosphorylation of MAPK8 protein CTD PMID:34850538 surfactin C multiple interactions ISO MAPK8 (Homo sapiens) 6480464 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [surfactin peptide results in increased phosphorylation of MAPK8 protein] and KIRA6 inhibits the reaction [surfactin peptide results in increased phosphorylation of MAPK8 protein] CTD PMID:34850538 syringic acid decreases expression ISO MAPK8 (Homo sapiens) 6480464 syringic acid results in decreased expression of MAPK8 mRNA CTD PMID:33759321 T-2 toxin increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 T-2 Toxin results in increased phosphorylation of MAPK8 protein CTD PMID:36775139 tacrolimus hydrate decreases activity EXP 6480464 Tacrolimus results in decreased activity of MAPK8 protein CTD PMID:12892836 tacrolimus hydrate multiple interactions EXP 6480464 Tacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein] CTD PMID:12892836 tamoxifen multiple interactions ISO MAPK8 (Homo sapiens) 6480464 alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK8 protein] CTD PMID:14645110 tamoxifen multiple interactions ISO Mapk8 (Mus musculus) 6480464 Tamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein] and Tamoxifen inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein] CTD PMID:23038002 tamoxifen increases activity ISO MAPK8 (Homo sapiens) 6480464 Tamoxifen results in increased activity of MAPK8 protein CTD PMID:14645110 Tanshinone I multiple interactions ISO Mapk8 (Mus musculus) 6480464 tanshinone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:29906494 taurine decreases expression EXP 6480464 Taurine results in decreased expression of MAPK8 protein modified form CTD PMID:27501764 taurine multiple interactions EXP 6480464 [[Taurine binds to Zinc] which co-treated with poly(N-vinylpyrrolidine)] results in decreased expression of MAPK8 protein modified form more ... CTD PMID:26335259 and PMID:27501764 taurocholic acid multiple interactions ISO Mapk8 (Mus musculus) 6480464 NR1H4 gene mutant form promotes the reaction [Taurocholic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:28505368 TEMPO multiple interactions ISO Mapk8 (Mus musculus) 6480464 TEMPO inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein] CTD PMID:33290831 tenofovir disoproxil fumarate affects phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Tenofovir affects the phosphorylation of MAPK8 protein CTD PMID:27041070 tert-butyl hydroperoxide multiple interactions ISO Mapk8 (Mus musculus) 6480464 [phorone co-treated with tert-Butylhydroperoxide] results in increased phosphorylation of MAPK8 protein CTD PMID:20423716 tert-butyl hydroperoxide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK8 protein] CTD PMID:28063877 tert-butyl hydroperoxide increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased phosphorylation of MAPK8 protein CTD PMID:28063877 tetracaine multiple interactions EXP 6480464 1 more ... CTD PMID:11981161 tetracaine increases phosphorylation EXP 6480464 Tetracaine results in increased phosphorylation of MAPK8 protein CTD PMID:11981161 Tetrachlorobisphenol A multiple interactions ISO MAPK8 (Homo sapiens) 6480464 4-(6-bromo-1 more ... CTD PMID:36190352 Tetrachlorobisphenol A affects expression ISO MAPK8 (Homo sapiens) 6480464 tetrachlorodian affects the expression of MAPK8 mRNA CTD PMID:33582643 Tetrachlorobisphenol A increases expression ISO MAPK8 (Homo sapiens) 6480464 tetrachlorodian results in increased expression of MAPK8 mRNA CTD PMID:36190352 tetrachloromethane increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein CTD PMID:20589743 more ... tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of MAPK8 mRNA CTD PMID:31150632 tetrachloromethane increases phosphorylation EXP 6480464 Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein CTD PMID:17285312 and PMID:19066852 tetrachloromethane multiple interactions ISO Mapk8 (Mus musculus) 6480464 [Acetaminophen co-treated with Carbon Tetrachloride] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:20589743 more ... tetramethylpyrazine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 tetramethylpyrazine inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein] CTD PMID:26404762 thapsigargin increases phosphorylation EXP 6480464 Thapsigargin results in increased phosphorylation of MAPK8 protein CTD PMID:21147958 and PMID:32574669 thapsigargin multiple interactions EXP 6480464 GW 506033X inhibits the reaction [Thapsigargin results in increased phosphorylation of MAPK8 protein] CTD PMID:32574669 thapsigargin increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Thapsigargin results in increased phosphorylation of MAPK8 protein CTD PMID:24150608 thapsigargin multiple interactions ISO Mapk8 (Mus musculus) 6480464 imoxin inhibits the reaction [Thapsigargin results in increased phosphorylation of MAPK8 protein] CTD PMID:24150608 Theaflavin 3,3'-digallate multiple interactions EXP 6480464 theaflavin-3 and 3'-digallate inhibits the reaction [PDGFBB protein results in increased phosphorylation of MAPK8 protein] CTD PMID:35903325 Theaflavin 3,3'-digallate multiple interactions ISO Mapk8 (Mus musculus) 6480464 theaflavin-3 more ... CTD PMID:27871911 Theaflavin 3,3'-digallate decreases phosphorylation ISO Mapk8 (Mus musculus) 6480464 theaflavin-3 and 3'-digallate results in decreased phosphorylation of MAPK8 protein CTD PMID:32694992 thimerosal increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Thimerosal results in increased phosphorylation of MAPK8 protein CTD PMID:18495191 thimerosal increases expression ISO MAPK8 (Homo sapiens) 6480464 Thimerosal results in increased expression of MAPK8 mRNA CTD PMID:27188386 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA more ... CTD PMID:23830814 and PMID:35961375 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of MAPK8 mRNA and Thioacetamide results in increased expression of MAPK8 protein CTD PMID:34492290 and PMID:35961375 Thrombin increases phosphorylation EXP 6480464 Thrombin results in increased phosphorylation of MAPK8 protein CTD PMID:27841083 titanium dioxide increases expression ISO MAPK8 (Homo sapiens) 6480464 titanium dioxide results in increased expression of MAPK8 mRNA CTD PMID:22342292 titanium dioxide increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 titanium dioxide results in increased phosphorylation of MAPK8 protein CTD PMID:30098274 titanium dioxide multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Ferrosoferric Oxide binds to titanium dioxide] which results in increased phosphorylation of MAPK8 protein CTD PMID:30098274 titanium dioxide increases expression ISO Mapk8 (Mus musculus) 6480464 titanium dioxide results in increased expression of MAPK8 mRNA CTD PMID:23557971 tofacitinib multiple interactions ISO MAPK8 (Homo sapiens) 6480464 tofacitinib inhibits the reaction [OSM protein results in increased phosphorylation of MAPK8 protein] CTD PMID:21548952 toluene 2,4-diisocyanate increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Toluene 2 and 4-Diisocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:33075463 toluene 2,4-diisocyanate multiple interactions ISO Mapk8 (Mus musculus) 6480464 pyrazolanthrone inhibits the reaction [Toluene 2 and 4-Diisocyanate results in increased phosphorylation of MAPK8 protein] CTD PMID:33075463 toluene 2,4-diisocyanate multiple interactions ISO MAPK8 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [Toluene 2 and 4-Diisocyanate results in increased phosphorylation of MAPK8 protein] CTD PMID:33075463 toluene 2,4-diisocyanate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Toluene 2 and 4-Diisocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:33075463 trans-anethole multiple interactions ISO MAPK8 (Homo sapiens) 6480464 anethole inhibits the reaction [TNF protein results in increased activity of MAPK8 protein] CTD PMID:10871845 trans-chalcone multiple interactions ISO Mapk8 (Mus musculus) 6480464 Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:22155221 tributylstannane increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 tributyltin results in increased phosphorylation of MAPK8 protein CTD PMID:21626652 tricetin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 tricetin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:31176653 trichostatin A affects expression ISO MAPK8 (Homo sapiens) 6480464 trichostatin A affects the expression of MAPK8 mRNA CTD PMID:28542535 trichostatin A decreases expression ISO MAPK8 (Homo sapiens) 6480464 trichostatin A results in decreased expression of MAPK8 mRNA CTD PMID:22723015 and PMID:26272509 trichostatin A multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:15781658 more ... triclosan increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Triclosan results in increased phosphorylation of MAPK8 protein CTD PMID:34160118 triclosan affects expression ISO MAPK8 (Homo sapiens) 6480464 Triclosan affects the expression of MAPK8 mRNA CTD PMID:34681664 triclosan multiple interactions ISO Mapk8 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Triclosan results in increased phosphorylation of MAPK8 protein] and pyrazolanthrone inhibits the reaction [Triclosan results in increased phosphorylation of MAPK8 protein] CTD PMID:34160118 trifluoperazine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 trifluoperazine multiple interactions ISO Mapk8 (Mus musculus) 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 trifluoperazine multiple interactions EXP 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 trimellitic anhydride multiple interactions ISO MAPK8 (Homo sapiens) 6480464 trimellitic anhydride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 trimellitic anhydride increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 trimellitic anhydride results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 trimethylarsine oxide decreases expression EXP 6480464 trimethylarsine oxide results in decreased expression of MAPK8 mRNA CTD PMID:17481689 trimethyltin increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 trimethyltin results in increased phosphorylation of MAPK8 protein CTD PMID:26756313 trimethyltin multiple interactions ISO Mapk8 (Mus musculus) 6480464 magnolol inhibits the reaction [trimethyltin results in increased phosphorylation of MAPK8 protein] CTD PMID:26756313 troglitazone decreases expression ISO Mapk8 (Mus musculus) 6480464 troglitazone results in decreased expression of MAPK8 mRNA CTD PMID:28973697 troglitazone multiple interactions ISO MAPK8 (Homo sapiens) 6480464 troglitazone results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15064713 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions EXP 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 trovafloxacin increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 trovafloxacin results in increased phosphorylation of MAPK8 protein CTD PMID:33609687 trovafloxacin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK8 protein] CTD PMID:33609687 tunicamycin increases expression ISO Mapk8 (Mus musculus) 6480464 Tunicamycin results in increased expression of MAPK8 mRNA CTD PMID:17127020 tunicamycin increases phosphorylation EXP 6480464 Tunicamycin results in increased phosphorylation of MAPK8 protein CTD PMID:21147958 tyrphostin AG 1478 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 RTKI cpd inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] and RTKI cpd inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:11329622 and PMID:26514923 tyrphostin AG 1478 multiple interactions EXP 6480464 RTKI cpd inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein] CTD PMID:15574683 U-73122 multiple interactions ISO MAPK8 (Homo sapiens) 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:19927300 umbelliferone multiple interactions EXP 6480464 7-hydroxycoumarin inhibits the reaction [Glycochenodeoxycholic Acid results in increased phosphorylation of MAPK8 protein] and 7-hydroxycoumarin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:34979142 urethane increases expression ISO MAPK8 (Homo sapiens) 6480464 Urethane results in increased expression of MAPK8 mRNA CTD PMID:28818685 ursolic acid multiple interactions EXP 6480464 2 more ... CTD PMID:27274199 valproic acid decreases expression ISO Mapk8 (Mus musculus) 6480464 Valproic Acid results in decreased expression of MAPK8 mRNA CTD PMID:21427059 valproic acid increases methylation ISO MAPK8 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of MAPK8 gene CTD PMID:29501571 valproic acid increases expression ISO MAPK8 (Homo sapiens) 6480464 Valproic Acid results in increased expression of MAPK8 mRNA CTD PMID:25716160 and PMID:29501571 valproic acid decreases expression ISO MAPK8 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of MAPK8 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAPK8 mRNA CTD PMID:27188386 valproic acid increases phosphorylation EXP 6480464 Valproic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:23378038 vanillic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Vanillic Acid inhibits the reaction [INS protein results in increased expression of MAPK8 protein] CTD PMID:36764371 verapamil multiple interactions EXP 6480464 Verapamil inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15936777 Vernodalin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 MAPK8 protein affects the reaction [vernodalin results in increased phosphorylation of JUN protein] CTD PMID:32726518 vincaleukoblastine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Vinblastine results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 vincaleukoblastine multiple interactions ISO MAPK8 (Homo sapiens) 6480464 TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein] CTD PMID:12221076 vinclozolin affects expression ISO Mapk8 (Mus musculus) 6480464 vinclozolin affects the expression of MAPK8 mRNA CTD PMID:34182078 vinclozolin increases expression ISO Mapk8 (Mus musculus) 6480464 vinclozolin results in increased expression of MAPK8 mRNA CTD PMID:36642194 vitamin E increases activity ISO MAPK8 (Homo sapiens) 6480464 Vitamin E results in increased activity of MAPK8 protein CTD PMID:11522656 vitamin E decreases expression ISO MAPK8 (Homo sapiens) 6480464 Vitamin E results in decreased expression of MAPK8 mRNA CTD PMID:19244175 vorinostat multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with Vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:12893773 more ... WIN 55212-2 increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 (3R)-((2 more ... CTD PMID:20619260 withaferin A increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 withaferin A results in increased phosphorylation of MAPK8 protein CTD PMID:21964475 wogonin multiple interactions ISO Mapk8 (Mus musculus) 6480464 wogonin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:23362215 wortmannin multiple interactions ISO Mapk8 (Mus musculus) 6480464 wortmannin inhibits the reaction [3-(2-hydroxy-4-(1 more ... CTD PMID:18950629 wortmannin multiple interactions ISO MAPK8 (Homo sapiens) 6480464 Wortmannin inhibits the reaction [tetrachlorodian results in increased expression of MAPK8 mRNA] CTD PMID:36190352 wortmannin multiple interactions EXP 6480464 Wortmannin inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased phosphorylation of MAPK8 protein] CTD PMID:10611455 wortmannin decreases phosphorylation ISO Mapk8 (Mus musculus) 6480464 wortmannin results in decreased phosphorylation of MAPK8 protein CTD PMID:18950629 xanthohumol increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 xanthohumol results in increased phosphorylation of MAPK8 protein CTD PMID:35229981 Yessotoxin increases activity ISO Mapk8 (Mus musculus) 6480464 yessotoxin results in increased activity of MAPK8 protein CTD PMID:21945047 zearalenone increases phosphorylation ISO Mapk8 (Mus musculus) 6480464 Zearalenone results in increased phosphorylation of MAPK8 protein CTD PMID:21767629 zearalenone increases expression ISO Mapk8 (Mus musculus) 6480464 Zearalenone results in increased expression of MAPK8 mRNA CTD PMID:30717214 zidovudine increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Zidovudine results in increased phosphorylation of MAPK8 protein CTD PMID:27041070 zinc acetate multiple interactions EXP 6480464 [Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK8 protein modified form CTD PMID:27501764 zinc atom increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Zinc results in increased phosphorylation of MAPK8 protein CTD PMID:16606632 zinc atom multiple interactions ISO Mapk8 (Mus musculus) 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein and pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein] CTD PMID:30768131 zinc atom multiple interactions EXP 6480464 [[Taurine binds to Zinc] which co-treated with poly(N-vinylpyrrolidine)] results in decreased expression of MAPK8 protein modified form more ... CTD PMID:26335259 and PMID:27501764 zinc atom multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Clioquinol co-treated with Zinc] results in increased phosphorylation of MAPK8 protein CTD PMID:16648635 zinc dichloride multiple interactions ISO Mapk8 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein] more ... CTD PMID:11306679 more ... zinc sulfate increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Zinc Sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:16606632 zinc(0) increases phosphorylation ISO MAPK8 (Homo sapiens) 6480464 Zinc results in increased phosphorylation of MAPK8 protein CTD PMID:16606632 zinc(0) multiple interactions ISO Mapk8 (Mus musculus) 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein and pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein] CTD PMID:30768131 zinc(0) multiple interactions EXP 6480464 [[Taurine binds to Zinc] which co-treated with poly(N-vinylpyrrolidine)] results in decreased expression of MAPK8 protein modified form more ... CTD PMID:26335259 and PMID:27501764 zinc(0) multiple interactions ISO MAPK8 (Homo sapiens) 6480464 [Clioquinol co-treated with Zinc] results in increased phosphorylation of MAPK8 protein CTD PMID:16648635 zingerone increases expression EXP 6480464 zingerone results in increased expression of MAPK8 mRNA CTD PMID:36822304 zingerone multiple interactions EXP 6480464 zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of MAPK8 mRNA] CTD PMID:36822304 zoledronic acid multiple interactions ISO MAPK8 (Homo sapiens) 6480464 zoledronic acid promotes the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] CTD PMID:17059425
