Symbol:
Psmc4
Name:
proteasome 26S subunit, ATPase 4
RGD ID:
621102
Description:
Predicted to enable proteasome-activating activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within blastocyst development. Located in inclusion body. Part of cytosolic proteasome complex. Orthologous to human PSMC4 (proteasome 26S subunit, ATPase 4); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
26S protease regulatory subunit 6B; 26S proteasome AAA-ATPase subunit RPT3; 26S proteasome regulatory subunit 6B; proteasome (prosome, macropain) 26S subunit, ATPase, 4; proteasome 26S ATPase subunit 4; proteasome 26S subunit ATPase 4; S6 ATPase; TAT-binding protein 7; TBP-7; Tbp7
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
PSMC4 (proteasome 26S subunit, ATPase 4) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Psmc4 (proteasome (prosome, macropain) 26S subunit, ATPase, 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Psmc4 (proteasome 26S subunit, ATPase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
PSMC4 (proteasome 26S subunit, ATPase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
PSMC4 (proteasome 26S subunit, ATPase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Psmc4 (proteasome 26S subunit, ATPase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
PSMC4 (proteasome 26S subunit, ATPase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
PSMC4 (proteasome 26S subunit, ATPase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Psmc4 (proteasome 26S subunit, ATPase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
PSMC4 (proteasome 26S subunit, ATPase 4)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Psmc4 (proteasome (prosome, macropain) 26S subunit, ATPase, 4)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
psmc4 (proteasome 26S subunit, ATPase 4)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
rpt-3
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
RPT3
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Rpt3
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Rpt3R
Alliance
DIOPT (Ensembl Compara|Hieranoid|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
psmc4
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 92,476,690 - 92,485,268 (-) NCBI GRCr8 mRatBN7.2 1 83,349,127 - 83,357,497 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 83,348,592 - 83,357,494 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 88,759,384 - 88,767,734 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 97,217,473 - 97,225,843 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 90,515,238 - 90,523,588 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 84,978,220 - 84,986,536 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 84,978,206 - 84,986,581 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 86,194,919 - 86,203,235 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 83,151,149 - 83,159,464 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 83,229,258 - 83,237,575 (-) NCBI Celera 1 77,748,725 - 77,757,041 (-) NCBI Celera Cytogenetic Map 1 q21 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Psmc4 Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PSMC4 mRNA] CTD PMID:31150632 Psmc4 Rat (-)-epigallocatechin 3-gallate increases expression ISO PSMC4 (Homo sapiens) 6480464 epigallocatechin gallate results in increased expression of PSMC4 protein CTD PMID:31195006 Psmc4 Rat (1->4)-beta-D-glucan multiple interactions ISO Psmc4 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PSMC4 mRNA CTD PMID:36331819 Psmc4 Rat (S)-nicotine decreases expression ISO Psmc4 (Mus musculus) 6480464 Nicotine results in decreased expression of PSMC4 mRNA CTD PMID:17456735 Psmc4 Rat 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o and p'-DDT affects the expression of PSMC4 mRNA CTD PMID:17984292 Psmc4 Rat 1,2-dimethylhydrazine multiple interactions ISO Psmc4 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PSMC4 mRNA] CTD PMID:22206623 Psmc4 Rat 1,2-dimethylhydrazine increases expression ISO Psmc4 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of PSMC4 mRNA CTD PMID:22206623 Psmc4 Rat 17alpha-ethynylestradiol increases expression ISO Psmc4 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of PSMC4 mRNA CTD PMID:17942748 Psmc4 Rat 17beta-estradiol increases expression ISO Psmc4 (Mus musculus) 6480464 Estradiol results in increased expression of PSMC4 mRNA CTD PMID:39298647 Psmc4 Rat 1H-pyrazole increases expression ISO Psmc4 (Mus musculus) 6480464 pyrazole results in increased expression of PSMC4 mRNA CTD PMID:17945193 Psmc4 Rat 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Psmc4 (Mus musculus) 6480464 2 more ... CTD PMID:30294300 Psmc4 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Psmc4 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PSMC4 mRNA CTD PMID:18796159 and PMID:19770486 Psmc4 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PSMC4 mRNA CTD PMID:34747641 Psmc4 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Psmc4 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PSMC4 mRNA CTD PMID:21570461 Psmc4 Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of PSMC4 mRNA CTD PMID:21346803 Psmc4 Rat 2,6-dimethoxyphenol multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [pyrogallol 1 more ... CTD PMID:38598786 Psmc4 Rat 2-amino-14,16-dimethyloctadecan-3-ol decreases expression ISO PSMC4 (Homo sapiens) 6480464 2-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of PSMC4 protein CTD PMID:32044396 Psmc4 Rat 2-methylcholine affects expression ISO PSMC4 (Homo sapiens) 6480464 beta-methylcholine affects the expression of PSMC4 mRNA CTD PMID:21179406 Psmc4 Rat 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of PSMC4 mRNA CTD PMID:15890375 Psmc4 Rat 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of PSMC4 protein CTD PMID:34915118 Psmc4 Rat 4,4'-diaminodiphenylmethane increases expression ISO Psmc4 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of PSMC4 mRNA CTD PMID:18648102 Psmc4 Rat 4,4'-sulfonyldiphenol increases expression ISO Psmc4 (Mus musculus) 6480464 bisphenol S results in increased expression of PSMC4 mRNA CTD PMID:39298647 Psmc4 Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMC4 mRNA CTD PMID:15890375 Psmc4 Rat 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of PSMC4 mRNA CTD PMID:21346803 Psmc4 Rat 4-hydroxyphenyl retinamide increases expression ISO Psmc4 (Mus musculus) 6480464 Fenretinide results in increased expression of PSMC4 mRNA CTD PMID:28973697 Psmc4 Rat aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of PSMC4 mRNA CTD PMID:15890375 Psmc4 Rat aflatoxin B1 increases expression ISO PSMC4 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of PSMC4 mRNA CTD PMID:27153756 Psmc4 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PSMC4 mRNA CTD PMID:16483693 Psmc4 Rat arsane multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PSMC4 mRNA more ... CTD PMID:35809665 and PMID:39836092 Psmc4 Rat arsenic atom multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PSMC4 mRNA more ... CTD PMID:35809665 and PMID:39836092 Psmc4 Rat arsenic trichloride multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of PSMC4 mRNA CTD PMID:35809665 Psmc4 Rat arsenite(3-) multiple interactions ISO PSMC4 (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to PSMC4 protein] CTD PMID:32406909 Psmc4 Rat arsenous acid increases expression ISO PSMC4 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PSMC4 mRNA CTD PMID:29633893 Psmc4 Rat atrazine increases expression ISO PSMC4 (Homo sapiens) 6480464 Atrazine results in increased expression of PSMC4 mRNA CTD PMID:22378314 Psmc4 Rat azoxystrobin multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC4 mRNA CTD PMID:33854195 Psmc4 Rat benzo[a]pyrene increases expression ISO PSMC4 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of PSMC4 mRNA and Benzo(a)pyrene results in increased expression of PSMC4 protein CTD PMID:17292933 and PMID:21632981 Psmc4 Rat benzo[a]pyrene decreases expression ISO PSMC4 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of PSMC4 mRNA CTD PMID:34332006 Psmc4 Rat benzo[a]pyrene increases expression ISO Psmc4 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of PSMC4 mRNA CTD PMID:22228805 Psmc4 Rat beta-naphthoflavone increases expression ISO PSMC4 (Homo sapiens) 6480464 beta-Naphthoflavone results in increased expression of PSMC4 mRNA CTD PMID:19737606 Psmc4 Rat bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of PSMC4 mRNA CTD PMID:21318169 Psmc4 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PSMC4 mRNA CTD PMID:25181051 Psmc4 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PSMC4 mRNA CTD PMID:33296240 Psmc4 Rat bisphenol A affects expression ISO PSMC4 (Homo sapiens) 6480464 bisphenol A affects the expression of PSMC4 mRNA CTD PMID:30903817 Psmc4 Rat Bisphenol B increases expression ISO PSMC4 (Homo sapiens) 6480464 bisphenol B results in increased expression of PSMC4 protein CTD PMID:34186270 Psmc4 Rat bisphenol F increases expression ISO PSMC4 (Homo sapiens) 6480464 bisphenol F results in increased expression of PSMC4 protein CTD PMID:34186270 Psmc4 Rat bortezomib increases expression ISO PSMC4 (Homo sapiens) 6480464 Bortezomib results in increased expression of PSMC4 mRNA CTD PMID:20977926 Psmc4 Rat Brodifacoum decreases expression EXP 6480464 bromfenacoum results in decreased expression of PSMC4 protein CTD PMID:28903499 Psmc4 Rat bromobenzene affects binding EXP 6480464 bromobenzene metabolite binds to PSMC4 protein CTD PMID:17305373 Psmc4 Rat cadmium dichloride increases expression ISO PSMC4 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of PSMC4 mRNA CTD PMID:38568856 Psmc4 Rat caffeine increases expression ISO PSMC4 (Homo sapiens) 6480464 Caffeine results in increased expression of PSMC4 protein CTD PMID:31195006 Psmc4 Rat cannabidiol increases expression ISO PSMC4 (Homo sapiens) 6480464 Cannabidiol results in increased expression of PSMC4 mRNA CTD PMID:27714895 Psmc4 Rat captan increases expression ISO Psmc4 (Mus musculus) 6480464 Captan results in increased expression of PSMC4 mRNA CTD PMID:31558096 Psmc4 Rat carbon nanotube increases expression ISO Psmc4 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 more ... Psmc4 Rat carbon nanotube multiple interactions ISO Psmc4 (Mus musculus) 6480464 [Dibutyl Phthalate co-treated with Nanotubes and Carbon] results in increased expression of PSMC4 protein CTD PMID:34864091 Psmc4 Rat chlorpyrifos multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC4 mRNA CTD PMID:33854195 Psmc4 Rat choline multiple interactions ISO Psmc4 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PSMC4 gene CTD PMID:20938992 Psmc4 Rat clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of PSMC4 mRNA and Clofibrate results in increased expression of PSMC4 protein CTD PMID:16470657 and PMID:21318169 Psmc4 Rat cobalt dichloride increases expression ISO PSMC4 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of PSMC4 mRNA CTD PMID:19320972 and PMID:19376846 Psmc4 Rat cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of PSMC4 mRNA CTD PMID:24386269 Psmc4 Rat copper atom multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in decreased expression of PSMC4 mRNA CTD PMID:24690739 Psmc4 Rat copper(0) multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in decreased expression of PSMC4 mRNA CTD PMID:24690739 Psmc4 Rat copper(II) chloride increases expression ISO PSMC4 (Homo sapiens) 6480464 cupric chloride results in increased expression of PSMC4 mRNA CTD PMID:17211630 Psmc4 Rat copper(II) sulfate increases expression ISO PSMC4 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of PSMC4 mRNA CTD PMID:19549813 Psmc4 Rat cyclosporin A increases expression ISO Psmc4 (Mus musculus) 6480464 Cyclosporine results in increased expression of PSMC4 mRNA CTD PMID:19770486 Psmc4 Rat cyclosporin A decreases expression ISO PSMC4 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of PSMC4 mRNA CTD PMID:27989131 Psmc4 Rat cyclosporin A increases expression ISO PSMC4 (Homo sapiens) 6480464 Cyclosporine results in increased expression of PSMC4 mRNA CTD PMID:20106945 and PMID:25562108 Psmc4 Rat diarsenic trioxide increases expression ISO PSMC4 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PSMC4 mRNA CTD PMID:29633893 Psmc4 Rat diazinon increases methylation ISO PSMC4 (Homo sapiens) 6480464 Diazinon results in increased methylation of PSMC4 gene CTD PMID:22964155 Psmc4 Rat Dibutyl phosphate affects expression ISO PSMC4 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of PSMC4 mRNA CTD PMID:37042841 Psmc4 Rat dibutyl phthalate multiple interactions ISO Psmc4 (Mus musculus) 6480464 [Dibutyl Phthalate co-treated with Nanotubes and Carbon] results in increased expression of PSMC4 protein CTD PMID:34864091 Psmc4 Rat dibutyl phthalate increases expression ISO Psmc4 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of PSMC4 protein CTD PMID:34864091 Psmc4 Rat dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] affects the expression of PSMC4 mRNA CTD PMID:18636392 Psmc4 Rat dicrotophos increases expression ISO PSMC4 (Homo sapiens) 6480464 dicrotophos results in increased expression of PSMC4 mRNA CTD PMID:28302478 Psmc4 Rat diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of PSMC4 mRNA CTD PMID:15890375 Psmc4 Rat disodium selenite increases expression ISO PSMC4 (Homo sapiens) 6480464 Sodium Selenite results in increased expression of PSMC4 mRNA CTD PMID:18175754 Psmc4 Rat disulfiram multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in decreased expression of PSMC4 mRNA CTD PMID:24690739 Psmc4 Rat doxorubicin affects expression ISO PSMC4 (Homo sapiens) 6480464 Doxorubicin affects the expression of PSMC4 mRNA and Doxorubicin affects the expression of PSMC4 protein CTD PMID:29385562 and PMID:29803840 Psmc4 Rat elemental selenium increases expression ISO PSMC4 (Homo sapiens) 6480464 Selenium results in increased expression of PSMC4 mRNA CTD PMID:19244175 Psmc4 Rat elesclomol increases expression ISO PSMC4 (Homo sapiens) 6480464 elesclomol results in increased expression of PSMC4 mRNA CTD PMID:18723479 Psmc4 Rat epoxomicin multiple interactions ISO PSMC4 (Homo sapiens) 6480464 NFE2L1 protein affects the reaction [epoxomicin results in increased expression of PSMC4 mRNA] CTD PMID:27345029 Psmc4 Rat epoxomicin increases expression ISO PSMC4 (Homo sapiens) 6480464 epoxomicin results in increased expression of PSMC4 mRNA CTD PMID:27345029 Psmc4 Rat ethanol multiple interactions EXP 6480464 [Fish Oils co-treated with Ethanol] results in increased expression of PSMC4 mRNA CTD PMID:17347304 Psmc4 Rat fenthion decreases expression ISO Psmc4 (Mus musculus) 6480464 Fenthion results in decreased expression of PSMC4 mRNA CTD PMID:34813904 Psmc4 Rat fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of PSMC4 protein CTD PMID:33656234 Psmc4 Rat finasteride increases expression EXP 6480464 Finasteride results in increased expression of PSMC4 mRNA CTD PMID:24136188 Psmc4 Rat flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of PSMC4 mRNA CTD PMID:18035473 Psmc4 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of PSMC4 mRNA CTD PMID:24136188 Psmc4 Rat folic acid multiple interactions ISO Psmc4 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PSMC4 gene more ... CTD PMID:20938992 and PMID:22206623 Psmc4 Rat folpet increases expression ISO Psmc4 (Mus musculus) 6480464 folpet results in increased expression of PSMC4 mRNA CTD PMID:31558096 Psmc4 Rat FR900359 affects phosphorylation ISO PSMC4 (Homo sapiens) 6480464 FR900359 affects the phosphorylation of PSMC4 protein CTD PMID:37730182 Psmc4 Rat furfural multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [pyrogallol 1 and 3-dimethyl ether co-treated with Furaldehyde] results in increased expression of and affects the localization of PSMC4 protein CTD PMID:38598786 Psmc4 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of PSMC4 mRNA CTD PMID:22061828 Psmc4 Rat glyphosate multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC4 mRNA CTD PMID:33854195 Psmc4 Rat hyaluronic acid multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in increased expression of PSMC4 protein] CTD PMID:23178681 Psmc4 Rat hyaluronic acid decreases expression EXP 6480464 Hyaluronic Acid analog results in decreased expression of PSMC4 protein CTD PMID:23178681 Psmc4 Rat hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of PSMC4 protein CTD PMID:23178681 Psmc4 Rat hydrogen peroxide multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in increased expression of PSMC4 protein] CTD PMID:23178681 Psmc4 Rat hydrogen sulfide decreases expression ISO Psmc4 (Mus musculus) 6480464 Hydrogen Sulfide results in decreased expression of PSMC4 protein CTD PMID:29932956 Psmc4 Rat imidacloprid multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC4 mRNA CTD PMID:33854195 Psmc4 Rat ivermectin decreases expression ISO PSMC4 (Homo sapiens) 6480464 Ivermectin results in decreased expression of PSMC4 protein CTD PMID:32959892 Psmc4 Rat L-methionine multiple interactions ISO Psmc4 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PSMC4 gene CTD PMID:20938992 Psmc4 Rat lead(0) decreases expression ISO PSMC4 (Homo sapiens) 6480464 Lead results in decreased expression of PSMC4 mRNA CTD PMID:19921347 Psmc4 Rat leflunomide increases expression EXP 6480464 leflunomide results in increased expression of PSMC4 mRNA CTD PMID:24136188 Psmc4 Rat maneb multiple interactions ISO Psmc4 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of PSMC4 mRNA and Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of PSMC4 mRNA] CTD PMID:23963992 Psmc4 Rat maneb multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of PSMC4 mRNA CTD PMID:26498265 Psmc4 Rat manganese atom multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PSMC4 mRNA CTD PMID:39836092 Psmc4 Rat manganese(0) multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PSMC4 mRNA CTD PMID:39836092 Psmc4 Rat manganese(II) chloride multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PSMC4 mRNA CTD PMID:39836092 Psmc4 Rat melatonin multiple interactions ISO Psmc4 (Mus musculus) 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of PSMC4 mRNA] CTD PMID:23963992 Psmc4 Rat Mesaconitine increases expression EXP 6480464 mesaconitine results in increased expression of PSMC4 protein CTD PMID:37182599 Psmc4 Rat methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of PSMC4 mRNA CTD PMID:15890375 Psmc4 Rat methidathion decreases expression ISO Psmc4 (Mus musculus) 6480464 methidathion results in decreased expression of PSMC4 mRNA CTD PMID:34813904 Psmc4 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO PSMC4 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC4 mRNA CTD PMID:31806706 Psmc4 Rat N-methyl-4-phenylpyridinium decreases expression ISO Psmc4 (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of PSMC4 protein CTD PMID:26558463 Psmc4 Rat N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of PSMC4 mRNA CTD PMID:15890375 Psmc4 Rat nefazodone increases expression EXP 6480464 nefazodone results in increased expression of PSMC4 mRNA CTD PMID:24136188 Psmc4 Rat nicotine decreases expression ISO Psmc4 (Mus musculus) 6480464 Nicotine results in decreased expression of PSMC4 mRNA CTD PMID:17456735 Psmc4 Rat nimesulide increases expression EXP 6480464 nimesulide results in increased expression of PSMC4 mRNA CTD PMID:24136188 Psmc4 Rat oxidopamine increases expression EXP 6480464 Oxidopamine results in increased expression of PSMC4 mRNA CTD PMID:12486162 Psmc4 Rat ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] affects the expression of PSMC4 mRNA CTD PMID:18636392 Psmc4 Rat ozone increases expression ISO PSMC4 (Homo sapiens) 6480464 Ozone results in increased expression of PSMC4 mRNA CTD PMID:23033980 Psmc4 Rat paracetamol affects expression ISO Psmc4 (Mus musculus) 6480464 Acetaminophen affects the expression of PSMC4 mRNA CTD PMID:17562736 Psmc4 Rat paracetamol decreases expression ISO PSMC4 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of PSMC4 mRNA CTD PMID:25704631 Psmc4 Rat paracetamol increases expression ISO PSMC4 (Homo sapiens) 6480464 Acetaminophen results in increased expression of PSMC4 mRNA CTD PMID:22230336 Psmc4 Rat paraquat increases expression EXP 6480464 Paraquat results in increased expression of PSMC4 mRNA CTD PMID:18198484 Psmc4 Rat paraquat multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of PSMC4 mRNA CTD PMID:26498265 Psmc4 Rat paraquat multiple interactions ISO Psmc4 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of PSMC4 mRNA and Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of PSMC4 mRNA] CTD PMID:23963992 Psmc4 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Psmc4 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PSMC4 mRNA CTD PMID:36331819 Psmc4 Rat perfluorooctanoic acid increases expression ISO Psmc4 (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of PSMC4 mRNA CTD PMID:21318169 Psmc4 Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of PSMC4 mRNA CTD PMID:19162173 and PMID:21318169 Psmc4 Rat perfluorooctanoic acid multiple interactions ISO Psmc4 (Mus musculus) 6480464 PPARA protein affects the reaction [perfluorooctanoic acid results in increased expression of PSMC4 mRNA] CTD PMID:21318169 Psmc4 Rat phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of PSMC4 mRNA CTD PMID:19162173 and PMID:21318169 Psmc4 Rat phenobarbital affects expression ISO Psmc4 (Mus musculus) 6480464 Phenobarbital affects the expression of PSMC4 mRNA CTD PMID:23091169 Psmc4 Rat phlorizin increases expression ISO Psmc4 (Mus musculus) 6480464 Phlorhizin results in increased expression of PSMC4 mRNA CTD PMID:22538082 Psmc4 Rat phlorizin decreases expression ISO Psmc4 (Mus musculus) 6480464 Phlorhizin results in decreased expression of PSMC4 mRNA CTD PMID:22538082 Psmc4 Rat piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of PSMC4 mRNA CTD PMID:15890375 and PMID:22484513 Psmc4 Rat pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of PSMC4 mRNA CTD PMID:15890375 Psmc4 Rat pirinixic acid increases expression ISO Psmc4 (Mus musculus) 6480464 pirinixic acid results in increased expression of PSMC4 mRNA CTD PMID:18301758 and PMID:23811191 Psmc4 Rat pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of PSMC4 mRNA CTD PMID:19162173 and PMID:21318169 Psmc4 Rat rotenone increases expression ISO PSMC4 (Homo sapiens) 6480464 Rotenone results in increased expression of PSMC4 mRNA CTD PMID:27345029 Psmc4 Rat selenium atom increases expression ISO PSMC4 (Homo sapiens) 6480464 Selenium results in increased expression of PSMC4 mRNA CTD PMID:19244175 Psmc4 Rat sodium arsenite increases expression ISO PSMC4 (Homo sapiens) 6480464 sodium arsenite results in increased expression of PSMC4 mRNA CTD PMID:34032870 and PMID:38568856 Psmc4 Rat sodium arsenite multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PSMC4 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of PSMC4 mRNA CTD PMID:39836092 Psmc4 Rat sodium chloride multiple interactions ISO PSMC4 (Homo sapiens) 6480464 [Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in increased expression of and affects the localization of PSMC4 protein CTD PMID:38598786 Psmc4 Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PSMC4 mRNA] CTD PMID:31150632 Psmc4 Rat tetrachloromethane increases expression ISO Psmc4 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of PSMC4 mRNA CTD PMID:31919559 Psmc4 Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of PSMC4 mRNA CTD PMID:31150632 Psmc4 Rat thiabendazole multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC4 mRNA CTD PMID:33854195 Psmc4 Rat thiram increases expression ISO PSMC4 (Homo sapiens) 6480464 Thiram results in increased expression of PSMC4 mRNA CTD PMID:38568856 Psmc4 Rat titanium dioxide increases methylation ISO Psmc4 (Mus musculus) 6480464 titanium dioxide results in increased methylation of PSMC4 gene CTD PMID:35295148 Psmc4 Rat trimellitic anhydride increases expression ISO Psmc4 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of PSMC4 mRNA CTD PMID:19042947 Psmc4 Rat triphenyl phosphate affects expression ISO PSMC4 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of PSMC4 mRNA CTD PMID:37042841 Psmc4 Rat valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of PSMC4 mRNA CTD PMID:24136188 Psmc4 Rat valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of PSMC4 mRNA CTD PMID:21318169 Psmc4 Rat valproic acid increases expression ISO PSMC4 (Homo sapiens) 6480464 Valproic Acid results in increased expression of PSMC4 mRNA CTD PMID:23179753 Psmc4 Rat vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of PSMC4 mRNA CTD PMID:23034163 Psmc4 Rat vitamin E increases expression ISO PSMC4 (Homo sapiens) 6480464 Vitamin E results in increased expression of PSMC4 mRNA CTD PMID:19244175 Psmc4 Rat zearalenone decreases expression ISO Psmc4 (Mus musculus) 6480464 Zearalenone results in decreased expression of PSMC4 protein CTD PMID:36252740
Imported Annotations - KEGG (archival)
(+)-schisandrin B (EXP) (-)-epigallocatechin 3-gallate (ISO) (1->4)-beta-D-glucan (ISO) (S)-nicotine (ISO) 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (EXP) 1,2-dimethylhydrazine (ISO) 17alpha-ethynylestradiol (ISO) 17beta-estradiol (ISO) 1H-pyrazole (ISO) 2,2',4,4'-Tetrabromodiphenyl ether (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dinitrotoluene (EXP) 2,6-dimethoxyphenol (ISO) 2-amino-14,16-dimethyloctadecan-3-ol (ISO) 2-methylcholine (ISO) 2-nitrofluorene (EXP) 3-chloropropane-1,2-diol (EXP) 4,4'-diaminodiphenylmethane (ISO) 4,4'-sulfonyldiphenol (ISO) 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (EXP) 4-amino-2,6-dinitrotoluene (EXP) 4-hydroxyphenyl retinamide (ISO) aflatoxin B1 (EXP,ISO) ammonium chloride (EXP) arsane (ISO) arsenic atom (ISO) arsenic trichloride (ISO) arsenite(3-) (ISO) arsenous acid (ISO) atrazine (ISO) azoxystrobin (EXP) benzo[a]pyrene (ISO) beta-naphthoflavone (ISO) bis(2-ethylhexyl) phthalate (EXP) bisphenol A (EXP,ISO) Bisphenol B (ISO) bisphenol F (ISO) bortezomib (ISO) Brodifacoum (EXP) bromobenzene (EXP) cadmium dichloride (ISO) caffeine (ISO) cannabidiol (ISO) captan (ISO) carbon nanotube (ISO) chlorpyrifos (EXP) choline (ISO) clofibrate (EXP) cobalt dichloride (EXP,ISO) copper atom (ISO) copper(0) (ISO) copper(II) chloride (ISO) copper(II) sulfate (ISO) cyclosporin A (ISO) diarsenic trioxide (ISO) diazinon (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (ISO) dichlorine (EXP) dicrotophos (ISO) diethylstilbestrol (EXP) disodium selenite (ISO) disulfiram (ISO) doxorubicin (ISO) elemental selenium (ISO) elesclomol (ISO) epoxomicin (ISO) ethanol (EXP) fenthion (ISO) fenvalerate (EXP) finasteride (EXP) flavonoids (EXP) flutamide (EXP) folic acid (ISO) folpet (ISO) FR900359 (ISO) furfural (ISO) gentamycin (EXP) glyphosate (EXP) hyaluronic acid (EXP) hydrogen peroxide (EXP) hydrogen sulfide (ISO) imidacloprid (EXP) ivermectin (ISO) L-methionine (ISO) lead(0) (ISO) leflunomide (EXP) maneb (ISO) manganese atom (ISO) manganese(0) (ISO) manganese(II) chloride (ISO) melatonin (ISO) Mesaconitine (EXP) methapyrilene (EXP) methidathion (ISO) N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO) N-methyl-4-phenylpyridinium (ISO) N-nitrosodimethylamine (EXP) nefazodone (EXP) nicotine (ISO) nimesulide (EXP) oxidopamine (EXP) ozone (EXP,ISO) paracetamol (ISO) paraquat (EXP,ISO) perfluorooctane-1-sulfonic acid (ISO) perfluorooctanoic acid (EXP,ISO) phenobarbital (EXP,ISO) phlorizin (ISO) piperonyl butoxide (EXP) pirinixic acid (EXP,ISO) pregnenolone 16alpha-carbonitrile (EXP) rotenone (ISO) selenium atom (ISO) sodium arsenite (ISO) sodium chloride (ISO) tetrachloromethane (EXP,ISO) thiabendazole (EXP) thiram (ISO) titanium dioxide (ISO) trimellitic anhydride (ISO) triphenyl phosphate (ISO) valdecoxib (EXP) valproic acid (EXP,ISO) vinclozolin (EXP) vitamin E (ISO) zearalenone (ISO)
1.
Activity-dependent dynamics and sequestration of proteasomes in dendritic spines.
Bingol B and Schuman EM, Nature. 2006 Jun 29;441(7097):1144-8.
2.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
4.
Structures of the rat proteasomal ATPases: determination of highly conserved structural motifs and rules for their spacing.
Makino Y, etal., Biochem Biophys Res Commun 1996 Mar 27;220(3):1049-54.
5.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
7.
GOA pipeline
RGD automated data pipeline
8.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
10.
Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones.
Rousseau E, etal., J Biol Chem. 2009 Jan 16;284(3):1917-29. doi: 10.1074/jbc.M806256200. Epub 2008 Nov 5.
11.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Psmc4 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 92,476,690 - 92,485,268 (-) NCBI GRCr8 mRatBN7.2 1 83,349,127 - 83,357,497 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 83,348,592 - 83,357,494 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 88,759,384 - 88,767,734 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 97,217,473 - 97,225,843 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 90,515,238 - 90,523,588 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 84,978,220 - 84,986,536 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 84,978,206 - 84,986,581 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 86,194,919 - 86,203,235 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 83,151,149 - 83,159,464 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 83,229,258 - 83,237,575 (-) NCBI Celera 1 77,748,725 - 77,757,041 (-) NCBI Celera Cytogenetic Map 1 q21 NCBI
PSMC4 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 19 39,971,165 - 39,981,764 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 19 39,971,165 - 39,981,764 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 19 40,477,072 - 40,487,671 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 19 45,168,913 - 45,179,193 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 19 45,168,912 - 45,179,191 NCBI Celera 19 37,275,447 - 37,285,724 (+) NCBI Celera Cytogenetic Map 19 q13.2 NCBI HuRef 19 36,913,453 - 36,924,135 (+) NCBI HuRef CHM1_1 19 40,476,958 - 40,487,716 (+) NCBI CHM1_1 T2T-CHM13v2.0 19 42,791,375 - 42,801,971 (+) NCBI T2T-CHM13v2.0
Psmc4 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 7 27,741,127 - 27,749,517 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 7 27,741,132 - 27,749,526 (-) Ensembl GRCm39 Ensembl GRCm38 7 28,041,702 - 28,050,092 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 7 28,041,707 - 28,050,101 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 7 28,826,721 - 28,835,111 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 7 27,750,477 - 27,758,803 (-) NCBI MGSCv36 mm8 Celera 7 22,608,215 - 22,616,605 (-) NCBI Celera Cytogenetic Map 7 A3 NCBI cM Map 7 16.11 NCBI
Psmc4 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955578 1,113,445 - 1,120,370 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955578 1,113,445 - 1,120,050 (-) NCBI ChiLan1.0 ChiLan1.0
PSMC4 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 20 46,232,549 - 46,243,056 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 19 48,103,185 - 48,113,698 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 19 37,018,112 - 37,028,490 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 19 45,533,141 - 45,543,245 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 19 45,533,141 - 45,543,245 (+) Ensembl panpan1.1 panPan2
PSMC4 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 1 113,548,351 - 113,557,725 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 1 113,548,373 - 113,557,630 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 1 112,952,245 - 112,961,621 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 1 114,148,644 - 114,157,982 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 1 114,148,650 - 114,157,892 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 1 113,707,548 - 113,716,884 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 1 113,340,335 - 113,349,711 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 1 114,334,441 - 114,343,783 (-) NCBI UU_Cfam_GSD_1.0
Psmc4 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024409349 14,094,546 - 14,100,215 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936661 2,522,615 - 2,528,284 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936661 2,522,665 - 2,528,279 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
PSMC4
PSMC4 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 6 34,486,303 - 34,495,392 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 6 34,486,338 - 34,495,251 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666073 12,578,624 - 12,587,383 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Psmc4
.
Predicted Target Of
Count of predictions: 34 Count of miRNA genes: 30 Interacting mature miRNAs: 33 Transcripts: ENSRNOT00000025819 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
2313059 Bss55 Bone structure and strength QTL 55 3.2 0.0001 tibia size trait (VT:0100001) tibia midshaft cross-sectional area (CMO:0001717) 1 43284731 118944897 Rat 631688 Hcas2 Hepatocarcinoma susceptibility QTL 2 3 0.0001 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 1 5925874 115540829 Rat 1578649 Bmd8 Bone mineral density QTL 8 4.9 femur mineral mass (VT:0010011) trabecular volumetric bone mineral density (CMO:0001729) 1 49393172 94393172 Rat 1582234 Gluco18 Glucose level QTL 18 3.4 0.0003 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 78479925 123479925 Rat 1358359 Sradr1 Stress Responsive Adrenal Weight QTL 1 4.74 adrenal gland mass (VT:0010420) both adrenal glands wet weight (CMO:0000164) 1 30882023 123479925 Rat 634314 Niddm44 Non-insulin dependent diabetes mellitus QTL 44 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 49393289 199050459 Rat 1578780 Cm52 Cardiac mass QTL 52 3.3 0.0001 heart mass (VT:0007028) heart wet weight (CMO:0000069) 1 81591954 219808434 Rat 1578654 Bss10 Bone structure and strength QTL 10 4 femur morphology trait (VT:0000559) femoral neck cortical cross-sectional area (CMO:0001702) 1 49393172 159356837 Rat 1554320 Bmd1 Bone mineral density QTL 1 12.2 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 1 509108 86060548 Rat 2302059 Pia36 Pristane induced arthritis QTL 36 3.8 0.001 blood immunoglobulin amount (VT:0002460) serum immunoglobulin G1 level (CMO:0002115) 1 43333002 88333002 Rat 1300121 Hrtrt1 Heart rate QTL 1 3.7 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 1 65789093 115540829 Rat 7421628 Bp361 Blood pressure QTL 361 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 66023617 118608521 Rat 631495 Bp96 Blood pressure QTL 96 4.52 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 22340647 102268831 Rat 70225 Bp58 Blood pressure QTL 58 3.3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 32356093 162846471 Rat 631512 Scl6 Serum cholesterol level QTL 6 9.6 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 1 72197680 90508767 Rat 2298545 Neuinf8 Neuroinflammation QTL 8 4.6 nervous system integrity trait (VT:0010566) spinal cord beta-2 microglobulin mRNA level (CMO:0002125) 1 57336763 151090257 Rat 2313072 Bss53 Bone structure and strength QTL 53 4.3 0.0001 tibia length (VT:0004357) tibia length (CMO:0000450) 1 43284731 118944897 Rat 10059597 Bp377 Blood pressure QTL 377 3.42 0.025 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 32737458 199368955 Rat 2313078 Bss54 Bone structure and strength QTL 54 3.5 0.0001 tibia area (VT:1000281) tibia midshaft cross-sectional area (CMO:0001717) 1 43284731 118944897 Rat 1549903 Bp267 Blood pressure QTL 267 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 77876254 106047988 Rat 2313083 Bmd74 Bone mineral density QTL 74 4 0.0001 tibia mineral mass (VT:1000283) total volumetric bone mineral density (CMO:0001728) 1 82174743 118944897 Rat 2313402 Anxrr24 Anxiety related response QTL 24 aggression-related behavior trait (VT:0015014) tameness/aggressiveness composite score (CMO:0002136) 1 48963584 144267916 Rat 4889494 Scort2 Serum corticosterone level QTL 2 4.2 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 1 80592172 125592172 Rat 61342 Bp27 Blood pressure QTL 27 3.4 0.0006 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 56732668 98773277 Rat 1300172 Bp172 Blood pressure QTL 172 3.56 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 1 32737273 90665040 Rat 61344 Bp29 Blood pressure QTL 29 7.5 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 78350581 123350581 Rat 1358192 Ept13 Estrogen-induced pituitary tumorigenesis QTL 13 3.4 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 1 77494165 122494165 Rat 2313094 Bss58 Bone structure and strength QTL 58 3.7 0.0001 tibia strength trait (VT:1000284) tibia total energy absorbed before break (CMO:0001736) 1 43284731 118944897 Rat 6903308 Scl36 Serum cholesterol QTL 36 2 0.0125 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 1 53863041 90532583 Rat 2300164 Bmd44 Bone mineral density QTL 44 5.4 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 1 56949932 101949932 Rat 2313099 Bss56 Bone structure and strength QTL 56 2.4 0.0001 tibia size trait (VT:0100001) tibia midshaft endosteal cross-sectional area (CMO:0001716) 1 43284731 118944897 Rat 2313098 Bmd70 Bone mineral density QTL 70 3.6 0.0001 tibia mineral mass (VT:1000283) compact volumetric bone mineral density (CMO:0001730) 1 43284731 118944897 Rat 152025249 Scl82 Serum cholesterol level QTL 82 4.77 blood cholesterol amount (VT:0000180) 1 50343510 99980958 Rat 10054135 Gmadr2 Adrenal mass QTL 2 1.97 0.0129 adrenal gland mass (VT:0010420) both adrenal glands wet weight (CMO:0000164) 1 77857876 122857876 Rat 7411712 Strs4 Sensitivity to stroke QTL 4 8.7 cerebrum integrity trait (VT:0010549) percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932) 1 78430536 123430536 Rat 2313051 Bss57 Bone structure and strength QTL 57 3.7 0.0001 tibia strength trait (VT:1000284) bone polar moment of inertia (CMO:0001558) 1 43284731 118944897 Rat 61433 Cia2 Collagen induced arthritis QTL 2 5 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 1 78430754 91209302 Rat
STS-T26522
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 1 83,349,154 - 83,349,325 (+) MAPPER mRatBN7.2 Rnor_6.0 1 84,978,239 - 84,978,409 NCBI Rnor6.0 Rnor_5.0 1 86,194,938 - 86,195,108 UniSTS Rnor5.0 RGSC_v3.4 1 83,151,167 - 83,151,337 UniSTS RGSC3.4 Celera 1 77,748,744 - 77,748,914 UniSTS Cytogenetic Map 1 q21 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000025819 ⟹ ENSRNOP00000025819
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 1 83,348,592 - 83,357,494 (-) Ensembl Rnor_6.0 Ensembl 1 84,978,206 - 84,986,581 (-) Ensembl
RefSeq Acc Id:
NM_057122 ⟹ NP_476463
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 92,476,690 - 92,485,060 (-) NCBI mRatBN7.2 1 83,349,127 - 83,357,497 (-) NCBI Rnor_6.0 1 84,978,220 - 84,986,536 (-) NCBI Rnor_5.0 1 86,194,919 - 86,203,235 (-) NCBI RGSC_v3.4 1 83,151,149 - 83,159,464 (-) RGD Celera 1 77,748,725 - 77,757,041 (-) NCBI
Sequence:
GGCTTGGTCACTATGGAGGAGATAGGCATTTTGGTGGAGAAAATTCAGGATGAGATCCCAGCACTGTCCGTGTCTCGGCCGCAGACCGGCCTGTCCTTTCTGGGACCCGAACCTGAGGACCTGGAGGA
hide sequence
RefSeq Acc Id:
XM_063267909 ⟹ XP_063123979
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 92,476,695 - 92,485,268 (-) NCBI
RefSeq Acc Id:
NP_476463 ⟸ NM_057122
- UniProtKB:
Q63570 (UniProtKB/Swiss-Prot), A6J9G3 (UniProtKB/TrEMBL)
- Sequence:
MEEIGILVEKIQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNA
hide sequence
Ensembl Acc Id:
ENSRNOP00000025819 ⟸ ENSRNOT00000025819
RefSeq Acc Id:
XP_063123979 ⟸ XM_063267909
- Peptide Label:
isoform X1
RGD ID: 13689860 Promoter ID: EPDNEW_R385 Type: multiple initiation site Name: Psmc4_1 Description: proteasome 26S subunit, ATPase 4 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 1 84,986,562 - 84,986,622 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2015-08-19
Psmc4
proteasome 26S subunit, ATPase 4
Psmc4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2004-09-10
Psmc4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
Symbol and Name status set to approved
1299863 APPROVED
2002-08-07
Psmc4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
Symbol and Name status set to provisional
70820 PROVISIONAL
