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Gene: Tkt (transketolase) Rattus norvegicus

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Symbol:

Tkt

Name:

transketolase

RGD ID:

621036

Description:

Enables cation binding activity; monosaccharide binding activity; and transketolase activity. Involved in pentose-phosphate shunt, non-oxidative branch. Located in endoplasmic reticulum membrane and peroxisome. Orthologous to human TKT (transketolase); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TKT (transketolase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Tkt (transketolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tkt (transketolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TKT (transketolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TKT (transketolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tkt (transketolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TKT (transketolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TKT (transketolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tkt (transketolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GRB10 (growth factor receptor bound protein 10)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	TKT (transketolase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tkt (transketolase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tkta (transketolase a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5103	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TKL1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TKL1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TKL2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TKL2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tkt-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8036	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tkt	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tkt	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	5,729,381 - 5,755,170 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	5,729,991 - 5,756,431 (+)	Ensembl				GRCr8
mRatBN7.2	16	5,723,764 - 5,748,702 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	5,723,762 - 5,748,698 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	5,735,981 - 5,760,697 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	6,881,435 - 6,906,151 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	5,734,559 - 5,759,275 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	6,609,670 - 6,634,608 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	6,609,668 - 6,634,595 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	6,543,529 - 6,568,467 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	5,908,759 - 5,933,695 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	9,440,328 - 9,465,209 (-)	NCBI		Celera
RGSC_v3.1	16	5,908,756 - 5,933,689 (+)	NCBI
Cytogenetic Map	16	p16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Gene Location:16:5729381..5755170

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tkt	Rat	Short Stature, Developmental Delay, and Congenital Heart Defects		ISO	TKT (Homo sapiens)	8554872	ClinVar Annotator: match by term: TKT-related condition \| ClinVar Annotator: match by term: Transketolase deficiency	ClinVar	PMID:25741868\|PMID:27259054\|PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tkt	Rat	Animal Mammary Neoplasms		ISO	TKT (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:12376462
Tkt	Rat	carcinoma		ISO	TKT (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:12376462
Tkt	Rat	Experimental Mammary Neoplasms		ISO	TKT (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:12376462
Tkt	Rat	Hypoxia		ISO	TKT (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:19579223
Tkt	Rat	Neoplasm Invasiveness		ISO	TKT (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:15654357
Tkt	Rat	Wernicke encephalopathy		ISO	TKT (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:3762968

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tkt	Rat	Short Stature, Developmental Delay, and Congenital Heart Defects		ISO	TKT (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tkt	Rat	(1->4)-beta-D-glucan	multiple interactions	ISO	Tkt (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TKT mRNA	CTD	PMID:36331819
Tkt	Rat	1,2-dimethylhydrazine	multiple interactions	ISO	Tkt (Mus musculus)	6480464	[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TKT mRNA	CTD	PMID:22206623
Tkt	Rat	1,2-dimethylhydrazine	affects expression	ISO	Tkt (Mus musculus)	6480464	1,2-Dimethylhydrazine affects the expression of TKT mRNA	CTD	PMID:22206623
Tkt	Rat	1,3-dinitrobenzene	increases expression	EXP		6480464	3-dinitrobenzene results in increased expression of TKT mRNA	CTD	PMID:21983209
Tkt	Rat	1-chloro-2,4-dinitrobenzene	increases metabolic processing	ISO	TKT (Homo sapiens)	6480464	Dinitrochlorobenzene results in increased metabolism of TKT protein	CTD	PMID:29267982
Tkt	Rat	1-naphthyl isothiocyanate	increases expression	EXP		6480464	1-Naphthylisothiocyanate results in increased expression of TKT mRNA	CTD	PMID:30723492
Tkt	Rat	17alpha-ethynylestradiol	increases expression	ISO	Tkt (Mus musculus)	6480464	Ethinyl Estradiol results in increased expression of TKT mRNA	CTD	PMID:17942748
Tkt	Rat	17alpha-ethynylestradiol	multiple interactions	ISO	Tkt (Mus musculus)	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TKT mRNA	CTD	PMID:17942748
Tkt	Rat	17beta-estradiol	multiple interactions	EXP		6480464	[bisphenol A co-treated with Estradiol] results in decreased expression of TKT mRNA	CTD	PMID:26496021
Tkt	Rat	17beta-estradiol	decreases expression	ISO	Tkt (Mus musculus)	6480464	Estradiol results in decreased expression of TKT mRNA	CTD	PMID:39298647
Tkt	Rat	17beta-estradiol	decreases expression	EXP		6480464	Estradiol results in decreased expression of TKT mRNA; Estradiol results in decreased expression of TKT more ...	CTD	PMID:32145629
Tkt	Rat	17beta-estradiol	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Estradiol co-treated with TGFB1 protein] results in decreased expression of TKT mRNA	CTD	PMID:30165855
Tkt	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	Tkt (Mus musculus)	6480464	[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of TKT mRNA; [Tetrachlorodibenzodioxin co-treated more ...	CTD	PMID:16214954\|PMID:17942748
Tkt	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of TKT mRNA	CTD	PMID:33387578
Tkt	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of TKT mRNA	CTD	PMID:34747641
Tkt	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Tkt (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of TKT mRNA	CTD	PMID:21570461
Tkt	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of TKT mRNA	CTD	PMID:16054898
Tkt	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	Tkt (Mus musculus)	6480464	Tetrachlorodibenzodioxin results in increased expression of TKT mRNA	CTD	PMID:18796159
Tkt	Rat	2,4-dibromophenyl 2,4,5-tribromophenyl ether	increases expression	EXP		6480464	2,2',4,4',5-brominated diphenyl ether results in increased expression of TKT protein	CTD	PMID:19954255
Tkt	Rat	2,4-dibromophenyl 2,4,5-tribromophenyl ether	increases expression	ISO	Tkt (Mus musculus)	6480464	2,2',4,4',5-brominated diphenyl ether results in increased expression of TKT protein	CTD	PMID:18550172
Tkt	Rat	2,6-dimethoxyphenol	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Sodium Chloride co-treated with pyrogallol 1,3-dimethyl ether] results in decreased expression of and affects the more ...	CTD	PMID:38598786
Tkt	Rat	2-acetamidofluorene	multiple interactions	EXP		6480464	[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TKT mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] more ...	CTD	PMID:14656948\|PMID:16158176
Tkt	Rat	2-hydroxypropanoic acid	increases expression	ISO	TKT (Homo sapiens)	6480464	Lactic Acid results in increased expression of TKT mRNA	CTD	PMID:30851411
Tkt	Rat	3-chloropropane-1,2-diol	increases expression	EXP		6480464	alpha-Chlorohydrin results in increased expression of TKT mRNA; alpha-Chlorohydrin results in increased expression of TKT more ...	CTD	PMID:28522335\|PMID:34915118
Tkt	Rat	3-chloropropane-1,2-diol	decreases expression	EXP		6480464	alpha-Chlorohydrin analog results in decreased expression of TKT protein; alpha-Chlorohydrin results in decreased expression of more ...	CTD	PMID:26597043
Tkt	Rat	3H-1,2-dithiole-3-thione	increases expression	EXP		6480464	1,2-dithiol-3-thione results in increased expression of TKT mRNA	CTD	PMID:19162173
Tkt	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	Tkt (Mus musculus)	6480464	bisphenol S results in decreased expression of TKT mRNA	CTD	PMID:39298647
Tkt	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	TKT (Homo sapiens)	6480464	bisphenol S results in increased expression of TKT protein	CTD	PMID:34186270
Tkt	Rat	4,4'-sulfonyldiphenol	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ...	CTD	PMID:36041667
Tkt	Rat	7,12-dimethyltetraphene	decreases expression	EXP		6480464	9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TKT mRNA	CTD	PMID:12376462
Tkt	Rat	acetamide	decreases expression	EXP		6480464	acetamide results in decreased expression of TKT mRNA	CTD	PMID:31881176
Tkt	Rat	aflatoxin B1	decreases expression	ISO	Tkt (Mus musculus)	6480464	Aflatoxin B1 results in decreased expression of TKT mRNA	CTD	PMID:19770486
Tkt	Rat	aflatoxin B1	decreases methylation	ISO	TKT (Homo sapiens)	6480464	Aflatoxin B1 results in decreased methylation of TKT intron	CTD	PMID:30157460
Tkt	Rat	all-trans-retinoic acid	increases expression	ISO	TKT (Homo sapiens)	6480464	Tretinoin results in increased expression of TKT mRNA	CTD	PMID:15894607\|PMID:17218384\|PMID:33167477
Tkt	Rat	all-trans-retinoic acid	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Tretinoin co-treated with arsenic trioxide] results in increased expression of TKT mRNA	CTD	PMID:15894607
Tkt	Rat	ammonium chloride	affects expression	EXP		6480464	Ammonium Chloride affects the expression of TKT mRNA	CTD	PMID:16483693
Tkt	Rat	Aroclor 1254	decreases expression	ISO	Tkt (Mus musculus)	6480464	Chlorodiphenyl (54% Chlorine) results in decreased expression of TKT mRNA	CTD	PMID:23650126
Tkt	Rat	arsane	increases expression	ISO	TKT (Homo sapiens)	6480464	Arsenic results in increased expression of TKT protein	CTD	PMID:19818359
Tkt	Rat	arsane	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:32525701\|PMID:39836092
Tkt	Rat	arsenic atom	increases expression	ISO	TKT (Homo sapiens)	6480464	Arsenic results in increased expression of TKT protein	CTD	PMID:19818359
Tkt	Rat	arsenic atom	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:32525701\|PMID:39836092
Tkt	Rat	arsenite(3-)	multiple interactions	ISO	TKT (Homo sapiens)	6480464	arsenite inhibits the reaction [G3BP1 protein binds to TKT protein]	CTD	PMID:32406909
Tkt	Rat	arsenous acid	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of TKT mRNA; Arsenic Trioxide inhibits more ...	CTD	PMID:15894607\|PMID:26598702
Tkt	Rat	astaxanthin	multiple interactions	ISO	Tkt (Mus musculus)	6480464	astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TKT mRNA]	CTD	PMID:16964424
Tkt	Rat	atrazine	increases expression	ISO	TKT (Homo sapiens)	6480464	Atrazine results in increased expression of TKT mRNA	CTD	PMID:22378314
Tkt	Rat	Augmentin	increases expression	ISO	TKT (Homo sapiens)	6480464	Amoxicillin-Potassium Clavulanate Combination results in increased expression of TKT mRNA	CTD	PMID:34767876
Tkt	Rat	azoxystrobin	multiple interactions	EXP		6480464	[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ...	CTD	PMID:33854195
Tkt	Rat	benfotiamine	multiple interactions	EXP		6480464	[benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein	CTD	PMID:12592403
Tkt	Rat	benfotiamine	multiple interactions	ISO	Tkt (Mus musculus)	6480464	benphothiamine inhibits the reaction [MAPT protein results in decreased activity of TKT protein]	CTD	PMID:29860433
Tkt	Rat	benzene	decreases expression	ISO	TKT (Homo sapiens)	6480464	Benzene results in decreased expression of TKT mRNA	CTD	PMID:20036648
Tkt	Rat	benzo[a]pyrene	increases expression	ISO	Tkt (Mus musculus)	6480464	Benzo(a)pyrene results in increased expression of TKT mRNA	CTD	PMID:21715664
Tkt	Rat	benzo[a]pyrene	affects methylation	ISO	TKT (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of TKT promoter	CTD	PMID:27901495
Tkt	Rat	benzo[a]pyrene	decreases expression	ISO	Tkt (Mus musculus)	6480464	Benzo(a)pyrene results in decreased expression of TKT mRNA	CTD	PMID:22228805
Tkt	Rat	benzo[a]pyrene	multiple interactions	ISO	Tkt (Mus musculus)	6480464	AHR protein affects the reaction [Benzo(a)pyrene affects the expression of TKT mRNA]	CTD	PMID:22228805
Tkt	Rat	benzo[e]pyrene	decreases methylation	ISO	TKT (Homo sapiens)	6480464	benzo(e)pyrene results in decreased methylation of TKT intron	CTD	PMID:30157460
Tkt	Rat	beta-naphthoflavone	increases expression	ISO	TKT (Homo sapiens)	6480464	beta-Naphthoflavone results in increased expression of TKT protein	CTD	PMID:39638853
Tkt	Rat	bis(2-ethylhexyl) phthalate	increases expression	ISO	Tkt (Mus musculus)	6480464	Diethylhexyl Phthalate results in increased expression of TKT mRNA; Diethylhexyl Phthalate results in increased expression more ...	CTD	PMID:36356568
Tkt	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	Tkt (Mus musculus)	6480464	Diethylhexyl Phthalate results in decreased expression of TKT mRNA	CTD	PMID:33754040\|PMID:34319233
Tkt	Rat	bisphenol A	affects expression	ISO	TKT (Homo sapiens)	6480464	bisphenol A affects the expression of TKT mRNA	CTD	PMID:20170705\|PMID:30903817
Tkt	Rat	bisphenol A	decreases expression	ISO	TKT (Homo sapiens)	6480464	bisphenol A results in decreased expression of TKT protein	CTD	PMID:37567409
Tkt	Rat	bisphenol A	decreases expression	ISO	Tkt (Mus musculus)	6480464	bisphenol A results in decreased expression of TKT protein	CTD	PMID:35999755
Tkt	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of TKT mRNA; bisphenol A results in decreased expression more ...	CTD	PMID:30816183\|PMID:32145629
Tkt	Rat	bisphenol A	increases expression	ISO	TKT (Homo sapiens)	6480464	bisphenol A results in increased expression of TKT mRNA	CTD	PMID:29275510
Tkt	Rat	bisphenol A	increases methylation	EXP		6480464	bisphenol A results in increased methylation of TKT gene	CTD	PMID:28505145
Tkt	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of TKT mRNA	CTD	PMID:25181051
Tkt	Rat	bisphenol A	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ...	CTD	PMID:26496021\|PMID:36041667
Tkt	Rat	bisphenol AF	increases expression	ISO	TKT (Homo sapiens)	6480464	bisphenol AF results in increased expression of TKT protein	CTD	PMID:34186270
Tkt	Rat	Bisphenol B	increases expression	ISO	TKT (Homo sapiens)	6480464	bisphenol B results in increased expression of TKT protein	CTD	PMID:34186270
Tkt	Rat	bisphenol F	increases expression	ISO	TKT (Homo sapiens)	6480464	bisphenol F results in increased expression of TKT protein	CTD	PMID:34186270
Tkt	Rat	bisphenol F	multiple interactions	EXP		6480464	[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ...	CTD	PMID:36041667
Tkt	Rat	buspirone	decreases expression	EXP		6480464	Buspirone results in decreased expression of TKT mRNA	CTD	PMID:24136188
Tkt	Rat	butan-1-ol	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ...	CTD	PMID:29432896
Tkt	Rat	butyric acid	decreases expression	ISO	TKT (Homo sapiens)	6480464	Butyric Acid results in decreased expression of TKT protein	CTD	PMID:34581912
Tkt	Rat	cadmium atom	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TKT more ...	CTD	PMID:29741670\|PMID:33040242
Tkt	Rat	cadmium dichloride	decreases expression	EXP		6480464	Cadmium Chloride results in decreased expression of TKT protein	CTD	PMID:21699967
Tkt	Rat	cadmium dichloride	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TKT more ...	CTD	PMID:29741670\|PMID:33040242
Tkt	Rat	caffeine	decreases phosphorylation	ISO	TKT (Homo sapiens)	6480464	Caffeine results in decreased phosphorylation of TKT protein	CTD	PMID:35688186
Tkt	Rat	carbamazepine	increases expression	EXP		6480464	Carbamazepine results in increased expression of TKT mRNA	CTD	PMID:17381134
Tkt	Rat	carbamazepine	decreases expression	EXP		6480464	Carbamazepine results in decreased expression of TKT mRNA	CTD	PMID:17381134
Tkt	Rat	carbon nanotube	decreases expression	ISO	Tkt (Mus musculus)	6480464	Nanotubes, Carbon analog results in decreased expression of TKT mRNA; Nanotubes, Carbon results in decreased more ...	CTD	PMID:25620056
Tkt	Rat	CGP 52608	multiple interactions	ISO	TKT (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to TKT gene]	CTD	PMID:28238834
Tkt	Rat	chlormequat chloride	increases expression	EXP		6480464	Chlormequat results in increased expression of TKT protein	CTD	PMID:34958886
Tkt	Rat	chloropicrin	decreases expression	ISO	TKT (Homo sapiens)	6480464	chloropicrin results in decreased expression of TKT mRNA	CTD	PMID:26352163
Tkt	Rat	chlorpyrifos	multiple interactions	EXP		6480464	[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ...	CTD	PMID:33854195
Tkt	Rat	chlorpyrifos	decreases expression	ISO	Tkt (Mus musculus)	6480464	Chlorpyrifos results in decreased expression of TKT mRNA	CTD	PMID:37019170
Tkt	Rat	choline	multiple interactions	ISO	Tkt (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ...	CTD	PMID:20938992
Tkt	Rat	cisplatin	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Cisplatin co-treated with jinfukang] results in increased expression of TKT mRNA	CTD	PMID:27392435
Tkt	Rat	clavulanic acid	increases expression	ISO	TKT (Homo sapiens)	6480464	Clavulanic Acid results in increased expression of TKT mRNA	CTD	PMID:34767876
Tkt	Rat	cobalt dichloride	increases expression	ISO	TKT (Homo sapiens)	6480464	cobaltous chloride results in increased expression of TKT mRNA	CTD	PMID:17553155\|PMID:19320972
Tkt	Rat	cocaine	affects expression	ISO	TKT (Homo sapiens)	6480464	Cocaine affects the expression of TKT protein	CTD	PMID:19393250
Tkt	Rat	copper atom	affects binding	ISO	TKT (Homo sapiens)	6480464	TKT protein binds to Copper	CTD	PMID:15359738
Tkt	Rat	copper(0)	affects binding	ISO	TKT (Homo sapiens)	6480464	TKT protein binds to Copper	CTD	PMID:15359738
Tkt	Rat	copper(II) chloride	increases expression	ISO	TKT (Homo sapiens)	6480464	cupric chloride results in increased expression of TKT mRNA	CTD	PMID:17211630
Tkt	Rat	crocidolite asbestos	decreases expression	ISO	Tkt (Mus musculus)	6480464	Asbestos, Crocidolite results in decreased expression of TKT mRNA	CTD	PMID:19446018
Tkt	Rat	CU-O LINKAGE	increases expression	ISO	TKT (Homo sapiens)	6480464	cupric oxide results in increased expression of TKT protein	CTD	PMID:25470785
Tkt	Rat	cyclosporin A	increases expression	ISO	TKT (Homo sapiens)	6480464	Cyclosporine results in increased expression of TKT mRNA	CTD	PMID:25562108
Tkt	Rat	decabromodiphenyl ether	increases expression	EXP		6480464	decabromobiphenyl ether results in increased expression of TKT mRNA	CTD	PMID:23914054
Tkt	Rat	dextran sulfate	decreases expression	ISO	Tkt (Mus musculus)	6480464	Dextran Sulfate results in decreased expression of TKT mRNA	CTD	PMID:35093514
Tkt	Rat	diarsenic trioxide	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Tretinoin co-treated with Arsenic Trioxide] results in increased expression of TKT mRNA; Arsenic Trioxide inhibits more ...	CTD	PMID:15894607\|PMID:26598702
Tkt	Rat	diazinon	increases methylation	ISO	TKT (Homo sapiens)	6480464	Diazinon results in increased methylation of TKT gene	CTD	PMID:22964155
Tkt	Rat	Dibutyl phosphate	affects expression	ISO	TKT (Homo sapiens)	6480464	di-n-butylphosphoric acid affects the expression of TKT mRNA	CTD	PMID:37042841
Tkt	Rat	dibutyl phthalate	decreases expression	ISO	Tkt (Mus musculus)	6480464	Dibutyl Phthalate results in decreased expression of TKT mRNA	CTD	PMID:21266533
Tkt	Rat	dibutyl phthalate	decreases expression	EXP		6480464	Dibutyl Phthalate results in decreased expression of TKT mRNA	CTD	PMID:17379624\|PMID:21266533
Tkt	Rat	diethylstilbestrol	increases expression	EXP		6480464	Diethylstilbestrol results in increased expression of TKT mRNA	CTD	PMID:37077353
Tkt	Rat	diquat	increases expression	ISO	Tkt (Mus musculus)	6480464	Diquat results in increased expression of TKT mRNA	CTD	PMID:36851058
Tkt	Rat	diuron	increases expression	EXP		6480464	Diuron results in increased expression of TKT mRNA	CTD	PMID:21551480
Tkt	Rat	dorsomorphin	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Tkt	Rat	doxorubicin	increases expression	ISO	TKT (Homo sapiens)	6480464	Doxorubicin results in increased expression of TKT mRNA	CTD	PMID:29803840
Tkt	Rat	elemental selenium	increases expression	ISO	TKT (Homo sapiens)	6480464	Selenium results in increased expression of TKT mRNA	CTD	PMID:19244175
Tkt	Rat	endosulfan	increases expression	EXP		6480464	Endosulfan results in increased expression of TKT mRNA	CTD	PMID:29391264
Tkt	Rat	enzyme inhibitor	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ...	CTD	PMID:23301498
Tkt	Rat	felbamate	increases expression	EXP		6480464	felbamate results in increased expression of TKT mRNA	CTD	PMID:17381134
Tkt	Rat	fenthion	decreases expression	ISO	Tkt (Mus musculus)	6480464	Fenthion results in decreased expression of TKT mRNA	CTD	PMID:34813904
Tkt	Rat	finasteride	increases expression	EXP		6480464	Finasteride results in increased expression of TKT mRNA	CTD	PMID:24136188
Tkt	Rat	flutamide	increases expression	EXP		6480464	Flutamide results in increased expression of TKT mRNA	CTD	PMID:24136188
Tkt	Rat	folic acid	multiple interactions	ISO	Tkt (Mus musculus)	6480464	[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TKT mRNA; [Methionine deficiency co-treated more ...	CTD	PMID:20938992\|PMID:22206623
Tkt	Rat	FR900359	increases phosphorylation	ISO	TKT (Homo sapiens)	6480464	FR900359 results in increased phosphorylation of TKT protein	CTD	PMID:37730182
Tkt	Rat	furfural	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of more ...	CTD	PMID:38598786
Tkt	Rat	gabapentin	increases expression	EXP		6480464	gabapentin results in increased expression of TKT mRNA	CTD	PMID:17381134
Tkt	Rat	genistein	decreases expression	ISO	TKT (Homo sapiens)	6480464	Genistein results in decreased expression of TKT mRNA	CTD	PMID:16705744
Tkt	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of TKT mRNA	CTD	PMID:22061828
Tkt	Rat	glyphosate	multiple interactions	EXP		6480464	[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ...	CTD	PMID:33854195
Tkt	Rat	gold atom	decreases expression	ISO	Tkt (Mus musculus)	6480464	Gold analog results in decreased expression of TKT protein	CTD	PMID:24780912
Tkt	Rat	gold(0)	decreases expression	ISO	Tkt (Mus musculus)	6480464	Gold analog results in decreased expression of TKT protein	CTD	PMID:24780912
Tkt	Rat	hydroquinone	increases expression	ISO	TKT (Homo sapiens)	6480464	hydroquinone results in increased expression of TKT mRNA	CTD	PMID:31256213
Tkt	Rat	imidacloprid	multiple interactions	EXP		6480464	[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ...	CTD	PMID:33854195
Tkt	Rat	inulin	multiple interactions	ISO	Tkt (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TKT mRNA	CTD	PMID:36331819
Tkt	Rat	isotretinoin	decreases expression	ISO	TKT (Homo sapiens)	6480464	Isotretinoin results in decreased expression of TKT mRNA	CTD	PMID:20436886
Tkt	Rat	ivermectin	affects expression	ISO	TKT (Homo sapiens)	6480464	Ivermectin affects the expression of TKT protein	CTD	PMID:32959892
Tkt	Rat	ketoconazole	increases expression	EXP		6480464	Ketoconazole results in increased expression of TKT mRNA	CTD	PMID:37077353
Tkt	Rat	L-methionine	multiple interactions	ISO	Tkt (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ...	CTD	PMID:20938992
Tkt	Rat	lead(II) chloride	increases expression	ISO	TKT (Homo sapiens)	6480464	lead chloride results in increased expression of TKT mRNA	CTD	PMID:18654764
Tkt	Rat	levofloxacin	decreases expression	EXP		6480464	Levofloxacin results in decreased expression of TKT mRNA	CTD	PMID:24136188
Tkt	Rat	lithium atom	increases expression	EXP		6480464	Lithium results in increased expression of TKT protein	CTD	PMID:18296634
Tkt	Rat	lithium hydride	increases expression	EXP		6480464	Lithium results in increased expression of TKT protein	CTD	PMID:18296634
Tkt	Rat	manganese atom	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Tkt	Rat	manganese(0)	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Tkt	Rat	manganese(II) chloride	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Tkt	Rat	mercury dibromide	increases expression	ISO	TKT (Homo sapiens)	6480464	mercuric bromide results in increased expression of TKT mRNA	CTD	PMID:26272509
Tkt	Rat	mercury dibromide	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Tkt	Rat	methapyrilene	decreases methylation	ISO	TKT (Homo sapiens)	6480464	Methapyrilene results in decreased methylation of TKT intron	CTD	PMID:30157460
Tkt	Rat	methapyrilene	decreases expression	EXP		6480464	Methapyrilene results in decreased expression of TKT protein	CTD	PMID:30467583
Tkt	Rat	methidathion	decreases expression	ISO	Tkt (Mus musculus)	6480464	methidathion results in decreased expression of TKT mRNA	CTD	PMID:34813904
Tkt	Rat	methyl methanesulfonate	decreases expression	ISO	TKT (Homo sapiens)	6480464	Methyl Methanesulfonate results in decreased expression of TKT mRNA	CTD	PMID:23649840
Tkt	Rat	methylmercury chloride	increases expression	ISO	TKT (Homo sapiens)	6480464	methylmercuric chloride results in increased expression of TKT mRNA	CTD	PMID:23179753
Tkt	Rat	morphine	decreases expression	EXP		6480464	Morphine results in decreased expression of TKT protein	CTD	PMID:23056601
Tkt	Rat	N-methyl-N-nitrosourea	increases expression	EXP		6480464	Methylnitrosourea results in increased expression of TKT mRNA	CTD	PMID:16525678
Tkt	Rat	N-nitrosodiethylamine	multiple interactions	EXP		6480464	[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TKT mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] more ...	CTD	PMID:14656948\|PMID:16158176\|PMID:20360939
Tkt	Rat	N-nitrosodiethylamine	increases expression	EXP		6480464	Diethylnitrosamine results in increased expression of TKT mRNA	CTD	PMID:19638242
Tkt	Rat	nefazodone	increases expression	EXP		6480464	nefazodone results in increased expression of TKT mRNA	CTD	PMID:24136188
Tkt	Rat	p-chloromercuribenzoic acid	increases expression	ISO	TKT (Homo sapiens)	6480464	p-Chloromercuribenzoic Acid results in increased expression of TKT mRNA	CTD	PMID:26272509
Tkt	Rat	p-chloromercuribenzoic acid	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Tkt	Rat	paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of TKT mRNA	CTD	PMID:15084756\|PMID:30723492
Tkt	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of TKT mRNA	CTD	PMID:33387578
Tkt	Rat	paracetamol	increases expression	ISO	TKT (Homo sapiens)	6480464	Acetaminophen results in increased expression of TKT mRNA	CTD	PMID:22230336
Tkt	Rat	paracetamol	decreases expression	ISO	TKT (Homo sapiens)	6480464	Acetaminophen results in decreased expression of TKT mRNA	CTD	PMID:21420995
Tkt	Rat	paracetamol	affects expression	ISO	Tkt (Mus musculus)	6480464	Acetaminophen affects the expression of TKT mRNA	CTD	PMID:17562736
Tkt	Rat	PCB138	decreases expression	EXP		6480464	2,2',3',4,4',5-hexachlorobiphenyl results in decreased expression of TKT protein	CTD	PMID:21673325
Tkt	Rat	pentachlorophenol	increases expression	ISO	Tkt (Mus musculus)	6480464	Pentachlorophenol results in increased expression of TKT mRNA	CTD	PMID:23892564
Tkt	Rat	perfluorooctane-1-sulfonic acid	decreases expression	EXP		6480464	perfluorooctane sulfonic acid results in decreased expression of TKT mRNA	CTD	PMID:19162173
Tkt	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	Tkt (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TKT mRNA; [perfluorooctane sulfonic more ...	CTD	PMID:36331819
Tkt	Rat	perfluorooctane-1-sulfonic acid	increases expression	ISO	TKT (Homo sapiens)	6480464	perfluorooctane sulfonic acid results in increased expression of TKT mRNA	CTD	PMID:27153767
Tkt	Rat	phenethyl caffeate	multiple interactions	EXP		6480464	[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TKT mRNA	CTD	PMID:20360939
Tkt	Rat	phenobarbital	increases expression	EXP		6480464	Phenobarbital results in increased expression of TKT mRNA	CTD	PMID:17381134\|PMID:19162173
Tkt	Rat	phenylmercury acetate	increases expression	ISO	TKT (Homo sapiens)	6480464	Phenylmercuric Acetate results in increased expression of TKT mRNA	CTD	PMID:26272509
Tkt	Rat	phenylmercury acetate	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Tkt	Rat	phenytoin	increases expression	EXP		6480464	Phenytoin results in increased expression of TKT mRNA	CTD	PMID:17381134
Tkt	Rat	PhIP	decreases expression	EXP		6480464	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of TKT mRNA	CTD	PMID:12376462
Tkt	Rat	pirinixic acid	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ...	CTD	PMID:19710929
Tkt	Rat	pirinixic acid	increases expression	ISO	Tkt (Mus musculus)	6480464	pirinixic acid results in increased expression of TKT mRNA	CTD	PMID:16221962
Tkt	Rat	pregnenolone 16alpha-carbonitrile	increases expression	EXP		6480464	Pregnenolone Carbonitrile results in increased expression of TKT mRNA	CTD	PMID:19162173
Tkt	Rat	quercetin	decreases expression	EXP		6480464	Quercetin results in decreased expression of TKT protein	CTD	PMID:18095365
Tkt	Rat	quercetin	increases expression	ISO	TKT (Homo sapiens)	6480464	Quercetin results in increased expression of TKT mRNA	CTD	PMID:21632981
Tkt	Rat	rac-lactic acid	increases expression	ISO	TKT (Homo sapiens)	6480464	Lactic Acid results in increased expression of TKT mRNA	CTD	PMID:30851411
Tkt	Rat	resveratrol	decreases expression	ISO	Tkt (Mus musculus)	6480464	resveratrol results in decreased expression of TKT protein	CTD	PMID:25505154
Tkt	Rat	rotenone	increases oxidation	EXP		6480464	Rotenone results in increased oxidation of TKT protein	CTD	PMID:30951809
Tkt	Rat	rotenone	increases expression	EXP		6480464	Rotenone results in increased expression of TKT protein	CTD	PMID:35544339
Tkt	Rat	rotenone	decreases expression	EXP		6480464	Rotenone results in decreased expression of TKT mRNA	CTD	PMID:28374803
Tkt	Rat	SB 431542	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of TKT more ...	CTD	PMID:27188386\|PMID:37664457
Tkt	Rat	selenium atom	increases expression	ISO	TKT (Homo sapiens)	6480464	Selenium results in increased expression of TKT mRNA	CTD	PMID:19244175
Tkt	Rat	silicon dioxide	affects secretion	ISO	TKT (Homo sapiens)	6480464	Silicon Dioxide analog affects the secretion of TKT protein	CTD	PMID:25895662
Tkt	Rat	sodium arsenate	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[sodium arsenate results in increased abundance of Arsenic] which results in increased expression of TKT more ...	CTD	PMID:32525701
Tkt	Rat	sodium arsenate	increases expression	ISO	TKT (Homo sapiens)	6480464	sodium arsenate results in increased expression of TKT mRNA	CTD	PMID:12727804
Tkt	Rat	sodium arsenite	increases expression	ISO	TKT (Homo sapiens)	6480464	sodium arsenite results in increased expression of TKT mRNA	CTD	PMID:25493608\|PMID:39719251
Tkt	Rat	sodium arsenite	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Tkt	Rat	sodium arsenite	decreases expression	ISO	TKT (Homo sapiens)	6480464	sodium arsenite results in decreased expression of TKT mRNA	CTD	PMID:38568856
Tkt	Rat	sodium arsenite	increases expression	EXP		6480464	sodium arsenite results in increased expression of TKT protein	CTD	PMID:29459688
Tkt	Rat	sodium chloride	multiple interactions	ISO	TKT (Homo sapiens)	6480464	[Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of more ...	CTD	PMID:38598786
Tkt	Rat	sodium fluoride	decreases expression	ISO	Tkt (Mus musculus)	6480464	Sodium Fluoride results in decreased expression of TKT protein	CTD	PMID:28918527
Tkt	Rat	streptozocin	multiple interactions	EXP		6480464	[benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein	CTD	PMID:12592403
Tkt	Rat	sunitinib	increases expression	ISO	TKT (Homo sapiens)	6480464	Sunitinib results in increased expression of TKT mRNA	CTD	PMID:31533062
Tkt	Rat	T-2 toxin	affects expression	EXP		6480464	T-2 Toxin affects the expression of TKT protein	CTD	PMID:26141394
Tkt	Rat	tetrachloromethane	multiple interactions	EXP		6480464	[Olive Oil analog co-treated with Carbon Tetrachloride] affects the expression of TKT protein	CTD	PMID:25303780
Tkt	Rat	thiabendazole	multiple interactions	EXP		6480464	[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ...	CTD	PMID:33854195
Tkt	Rat	thimerosal	decreases expression	ISO	TKT (Homo sapiens)	6480464	Thimerosal results in decreased expression of TKT mRNA	CTD	PMID:27188386
Tkt	Rat	titanium dioxide	increases expression	ISO	Tkt (Mus musculus)	6480464	titanium dioxide results in increased expression of TKT mRNA	CTD	PMID:27760801
Tkt	Rat	titanium dioxide	decreases methylation	ISO	Tkt (Mus musculus)	6480464	titanium dioxide results in decreased methylation of TKT promoter	CTD	PMID:35295148
Tkt	Rat	trichloroethene	decreases expression	ISO	Tkt (Mus musculus)	6480464	Trichloroethylene results in decreased expression of TKT mRNA	CTD	PMID:19448997
Tkt	Rat	trichloroethene	increases expression	EXP		6480464	Trichloroethylene results in increased expression of TKT mRNA	CTD	PMID:33387578
Tkt	Rat	triphenyl phosphate	affects expression	ISO	TKT (Homo sapiens)	6480464	triphenyl phosphate affects the expression of TKT mRNA	CTD	PMID:37042841
Tkt	Rat	trovafloxacin	decreases expression	EXP		6480464	trovafloxacin results in decreased expression of TKT mRNA	CTD	PMID:24136188
Tkt	Rat	valdecoxib	increases expression	EXP		6480464	valdecoxib results in increased expression of TKT mRNA	CTD	PMID:24136188
Tkt	Rat	valproic acid	increases expression	ISO	TKT (Homo sapiens)	6480464	Valproic Acid results in increased expression of TKT mRNA	CTD	PMID:29154799
Tkt	Rat	valproic acid	affects expression	ISO	TKT (Homo sapiens)	6480464	Valproic Acid affects the expression of TKT mRNA	CTD	PMID:25979313
Tkt	Rat	valproic acid	affects expression	ISO	Tkt (Mus musculus)	6480464	Valproic Acid affects the expression of TKT mRNA	CTD	PMID:17292431
Tkt	Rat	vitamin E	increases expression	ISO	TKT (Homo sapiens)	6480464	Vitamin E results in increased expression of TKT mRNA	CTD	PMID:19244175
Tkt	Rat	zearalenone	decreases expression	ISO	Tkt (Mus musculus)	6480464	Zearalenone results in decreased expression of TKT protein	CTD	PMID:25058043

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tkt	Rat	D-xylulose 5-phosphate biosynthetic process	involved_in	ISO	Tkt (Mus musculus)	1624291	PMID:5360673	RGD	PMID:5360673
Tkt	Rat	glyceraldehyde-3-phosphate biosynthetic process	involved_in	ISO	TKT (Homo sapiens)	1624291	PMID:9611778	RGD	PMID:9611778
Tkt	Rat	pentose-phosphate shunt		IDA		1599574		RGD
Tkt	Rat	pentose-phosphate shunt	involved_in	ISO	Tkt (Mus musculus)	1624291	PMID:13405914, PMID:5360673	RGD	PMID:13405914\|PMID:5360673
Tkt	Rat	pentose-phosphate shunt	involved_in	ISO	TKT (Homo sapiens)	1624291	PMID:20667822	RGD	PMID:20667822
Tkt	Rat	pentose-phosphate shunt, non-oxidative branch		IDA		1580394		RGD
Tkt	Rat	pentose-phosphate shunt, non-oxidative branch	involved_in	IBA	MGI:105992\|PANTHER:PTN002877174\|RGD:621036	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tkt	Rat	pentose-phosphate shunt, non-oxidative branch	involved_in	ISO	Tkt (Mus musculus)	1624291	PMID:32295803	RGD	PMID:32295803
Tkt	Rat	pentose-phosphate shunt, non-oxidative branch	involved_in	IEA	ARBA:ARBA00091353	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Tkt	Rat	pentose-phosphate shunt, non-oxidative branch		IDA		1641816		RGD
Tkt	Rat	regulation of growth	acts_upstream_of_or_within	ISO	Tkt (Mus musculus)	1624291	MGI:2671068 PMID:12167708	RGD	PMID:12167708

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tkt	Rat	cytoplasm	located_in	IEA	ARBA:ARBA00026971	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Tkt	Rat	cytosol	is_active_in	ISO	Tkt (Mus musculus)	1624291	PMID:5360673	RGD	PMID:5360673
Tkt	Rat	endoplasmic reticulum membrane		IDA		1580394		RGD
Tkt	Rat	endoplasmic reticulum membrane	is_active_in	IBA	PANTHER:PTN002877174\|RGD:621036	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tkt	Rat	nuclear body	located_in	ISO	RGD:732645\|UniProtKB:P29401-1\|UniProtKB:P29401-2	1624291		RGD	GO_REF:0000052
Tkt	Rat	nucleoplasm	located_in	ISO	RGD:732645\|UniProtKB:P29401-1\|UniProtKB:P29401-2	1624291		RGD	GO_REF:0000052
Tkt	Rat	peroxisome		IDA		1580394		RGD

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tkt	Rat	calcium ion binding	enables	ISO	TKT (Homo sapiens)	1624291	PMID:20667822	RGD	PMID:20667822
Tkt	Rat	carbohydrate binding		IDA		1599574		RGD
Tkt	Rat	magnesium ion binding	enables	ISO	TKT (Homo sapiens)	1624291	PMID:9611778	RGD	PMID:9611778
Tkt	Rat	magnesium ion binding		IDA		1580394		RGD
Tkt	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Tkt	Rat	monosaccharide binding		IDA		1580394		RGD
Tkt	Rat	protein binding	enables	ISO	TKT (Homo sapiens)	1624291	UniProtKB:P54274 PMID:21044950	RGD	PMID:21044950
Tkt	Rat	protein homodimerization activity	enables	ISO	TKT (Homo sapiens)	1624291	PMID:20667822, PMID:9357955	RGD	PMID:20667822\|PMID:9357955
Tkt	Rat	thiamine pyrophosphate binding	enables	IBA	PANTHER:PTN000179046\|RGD:621036	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tkt	Rat	thiamine pyrophosphate binding		IDA		1580394		RGD
Tkt	Rat	transferase activity	enables	IEA	UniProtKB-KW:KW-0808	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Tkt	Rat	transketolase activity		IDA		1580394		RGD
Tkt	Rat	transketolase activity	enables	IEA	EC:2.2.1.1	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Tkt	Rat	transketolase activity	enables	IBA	MGI:105992\|PANTHER:PTN000179046\|RGD:621036\|UniProtKB:P29401	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tkt	Rat	transketolase activity	enables	IEA	RHEA:10508	1600115	GO_REF:0000116	RHEA	GO_REF:0000116
Tkt	Rat	transketolase activity	enables	IEA	ARBA:ARBA00087780	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Tkt	Rat	transketolase activity	enables	ISO	Tkt (Mus musculus)	1624291	PMID:12167708, PMID:5360673	RGD	PMID:12167708\|PMID:5360673
Tkt	Rat	transketolase activity	enables	ISO	TKT (Homo sapiens)	1624291	PMID:20667822, PMID:8419340, PMID:9357955, PMID:9611778	RGD	PMID:20667822\|PMID:8419340\|PMID:9357955\|PMID:9611778
Tkt	Rat	transketolase activity		IDA		1624966		RGD
Tkt	Rat	transketolase activity		IDA		1599574		RGD

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tkt	Rat	pentose phosphate pathway		IDA		1599574		RGD
Tkt	Rat	pentose phosphate pathway - non-oxidative phase		TAS		1641798		RGD
Tkt	Rat	pentose phosphate pathway - non-oxidative phase		TAS		1641814		RGD
Tkt	Rat	pentose phosphate pathway - non-oxidative phase		IDA		1580394		RGD

Imported Annotations - SMPDB

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tkt	Rat	pentose phosphate pathway		ISO	TKT (Homo sapiens)	10402751		SMPDB	SMP:00031
Tkt	Rat	ribose 5-phosphate isomerase deficiency pathway		ISO	TKT (Homo sapiens)	10402751		SMPDB	SMP:00519
Tkt	Rat	transaldolase deficiency pathway		ISO	TKT (Homo sapiens)	10402751		SMPDB	SMP:00520

Imported Annotations - KEGG (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tkt	Rat	pentose phosphate pathway		IEA		6907045		KEGG	rno:00030

BioCyc Pathways

pentose phosphate pathway (non-oxidative branch) I

#	Reference Title	Reference Citation
1.	Nucleotide and predicted amino acid sequence of a cDNA clone encoding part of human transketolase.	Abedinia M, etal., Biochem Biophys Res Commun 1992 Mar 31;183(3):1159-66.
2.	In situ localization of transketolase activity in epithelial cells of different rat tissues and subcellularly in liver parenchymal cells.	Boren J, etal., J Histochem Cytochem. 2006 Feb;54(2):191-9. Epub 2005 Aug 22.
3.	The pentose phosphate pathway in the endoplasmic reticulum.	Bublitz C and Steavenson S, J Biol Chem. 1988 Sep 15;263(26):12849-53.
4.	The interdependence of glycolytic and pentose cycle intermediates in ad libitum fed rats.	Casazza JP and Veech RL, J Biol Chem. 1986 Jan 15;261(2):690-8.
5.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
7.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
8.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
9.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
10.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
11.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
12.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
13.	GOA pipeline	RGD automated data pipeline
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Properties and functions of the thiamin diphosphate dependent enzyme transketolase.	Schenk G, etal., Int J Biochem Cell Biol. 1998 Dec;30(12):1297-318.
16.	Effect of Anabolic Steroid Nandrolone Decanoate on the Properties of Certain Enzymes in the Heart, Liver, and Muscle of Rats, and their Effect on Rats' Cardiac Electrophysiology.	Tylicki A, etal., Horm Metab Res. 2007 Apr;39(4):268-72.
17.	A humble hexose monophosphate pathway metabolite regulates short- and long-term control of lipogenesis.	Veech RL Proc Natl Acad Sci U S A. 2003 May 13;100(10):5578-80. Epub 2003 Apr 29.

PMID:8419340	PMID:9357955	PMID:9611778	PMID:12167708	PMID:17634366	PMID:19056867	PMID:19190083	PMID:20458337	PMID:20667822	PMID:22871113	PMID:23376485	PMID:23533145
PMID:25028661	PMID:33450132

Tkt
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	5,729,381 - 5,755,170 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	5,729,991 - 5,756,431 (+)	Ensembl				GRCr8
mRatBN7.2	16	5,723,764 - 5,748,702 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	5,723,762 - 5,748,698 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	5,735,981 - 5,760,697 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	6,881,435 - 6,906,151 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	5,734,559 - 5,759,275 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	6,609,670 - 6,634,608 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	6,609,668 - 6,634,595 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	6,543,529 - 6,568,467 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	5,908,759 - 5,933,695 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	9,440,328 - 9,465,209 (-)	NCBI		Celera
RGSC_v3.1	16	5,908,756 - 5,933,689 (+)	NCBI
Cytogenetic Map	16	p16	NCBI

TKT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	53,224,712 - 53,256,022 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	53,224,712 - 53,256,052 (-)	Ensembl			hg38	GRCh38
GRCh37	3	53,258,728 - 53,290,038 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	53,234,704 - 53,264,998 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	53,234,705 - 53,264,998	NCBI
Celera	3	53,225,747 - 53,257,192 (-)	NCBI		Celera
Cytogenetic Map	3	p21.1	NCBI
HuRef	3	53,308,475 - 53,339,480 (-)	NCBI		HuRef
CHM1_1	3	53,210,297 - 53,241,712 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	53,257,622 - 53,288,998 (-)	NCBI		T2T-CHM13v2.0

Tkt
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	30,271,088 - 30,296,681 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	30,270,316 - 30,296,677 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	30,549,131 - 30,574,724 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	30,548,359 - 30,574,720 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	31,362,335 - 31,387,908 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	29,378,158 - 29,403,731 (+)	NCBI		MGSCv36	mm8
Celera	14	26,805,317 - 26,830,435 (+)	NCBI		Celera
Cytogenetic Map	14	B	NCBI
cM Map	14	18.79	NCBI

Tkt
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	3,178,830 - 3,193,345 (-)	Ensembl
ChiLan1.0	NW_004955430	3,178,830 - 3,193,241 (-)	NCBI	ChiLan1.0	ChiLan1.0

TKT
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	53,207,948 - 53,252,434 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	53,212,734 - 53,257,204 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	53,168,426 - 53,199,003 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	54,389,549 - 54,420,704 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	54,389,549 - 54,420,704 (-)	Ensembl			panPan2	panpan1.1

TKT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	36,690,540 - 36,705,980 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	36,681,531 - 36,742,199 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	36,617,359 - 36,642,352 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	36,959,138 - 36,984,142 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	36,958,981 - 36,984,141 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	36,395,903 - 36,420,888 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	36,757,580 - 36,782,577 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	36,972,262 - 36,997,252 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tkt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	170,812,273 - 170,840,216 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	3,950,920 - 3,978,672 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	3,950,846 - 3,978,778 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TKT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	35,348,915 - 35,377,587 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	35,348,921 - 35,377,518 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	38,418,457 - 38,447,124 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TKT
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	14,620,340 - 14,650,694 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	14,620,287 - 14,650,655 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	152,245,198 - 152,275,549 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tkt
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624822	3,989,299 - 4,014,269 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624822	3,989,292 - 4,014,150 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants in Tkt
199 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	33
Count of miRNA genes:	30
Interacting mature miRNAs:	33
Transcripts:	ENSRNOT00000021862
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582235	Insul8	Insulin level QTL 8	3.3	0.0063	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	16	4234212	16278352	Rat
1549842	Bp248	Blood pressure QTL 248		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	387123	45387123	Rat
2307172	Activ4	Activity QTL 4	3.71	0.00023	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	1	33425095	Rat
1354584	Despr6	Despair related QTL 6	3.1	0.0067	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	39568015	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4234212	53708481	Rat
1354625	Despr7	Despair related QTL 7	3.16	0.016	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	4744222	49744222	Rat
61338	Bp23	Blood pressure QTL 23	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	4234212	16278352	Rat
61405	Niddm6	Non-insulin dependent diabetes mellitus QTL 6	3.66	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	16	1	26734272	Rat
631830	Alc7	Alcohol consumption QTL 7	2.9		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	1	26734272	Rat
7411664	Foco30	Food consumption QTL 30	11	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	4354822	49354822	Rat
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	16	387123	45387123	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	4234212	49757901	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	66955197	Rat
737825	Alc13	Alcohol consumption QTL 13	4.5		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	16061395	Rat
2303566	Bw90	Body weight QTL 90	2		body mass (VT:0001259)	body weight (CMO:0000012)	16	1	39568015	Rat
631524	Bp75	Blood pressure QTL 75		0.05	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	117710	8157035	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	839086	66195506	Rat
2306902	Bp339	Blood pressure QTL 339		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	3386790	49757901	Rat
1300133	Rf24	Renal function QTL 24	3.64		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	16	3386790	26128267	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	839086	66195506	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	839086	66195506	Rat
634355	Rends4	Renal damage susceptibility QTL 4		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	16	1	26734272	Rat
61372	Bp40	Blood pressure QTL 40	2.2		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	16	4234333	17730812	Rat
2293343	Glom16	Glomerulus QTL 16	7.4		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	16	839086	52786090	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	839086	66195506	Rat
6903319	Bw114	Body weight QTL 114	2.7	0.0037	body mass (VT:0001259)	body weight (CMO:0000012)	16	3301683	48301683	Rat

BE117994

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	5,747,569 - 5,747,727 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	6,633,476 - 6,633,633	NCBI	Rnor6.0
Rnor_5.0	16	6,567,335 - 6,567,492	UniSTS	Rnor5.0
RGSC_v3.4	16	5,932,565 - 5,932,722	UniSTS	RGSC3.4
Celera	16	9,441,301 - 9,441,458	UniSTS
RH 3.4 Map	16	33.2	UniSTS
Cytogenetic Map	16	p16	UniSTS

TKT

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	5,744,917 - 5,745,156 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	6,630,824 - 6,631,062	NCBI	Rnor6.0
Rnor_5.0	16	6,564,683 - 6,564,921	UniSTS	Rnor5.0
RGSC_v3.4	16	5,929,913 - 5,930,151	UniSTS	RGSC3.4
Cytogenetic Map	16	p16	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17


RefSeq Transcripts	NM_001436741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001436742	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001436743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_022592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252661	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232736	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U09256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021862 ⟹ ENSRNOP00000021862

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	5,730,230 - 5,755,157 (+)	Ensembl
mRatBN7.2 Ensembl	16	5,723,762 - 5,748,689 (+)	Ensembl
Rnor_6.0 Ensembl	16	6,609,668 - 6,634,595 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113496 ⟹ ENSRNOP00000095976

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	5,730,868 - 5,755,159 (+)	Ensembl
mRatBN7.2 Ensembl	16	5,724,393 - 5,748,698 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000129190 ⟹ ENSRNOP00000104051

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	5,729,991 - 5,755,157 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000145038 ⟹ ENSRNOP00000101850

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	5,730,819 - 5,756,431 (+)	Ensembl

RefSeq Acc Id:

NM_022592 ⟹ NP_072114

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	5,730,232 - 5,755,168 (+)	NCBI
mRatBN7.2	16	5,723,764 - 5,748,700 (+)	NCBI
Rnor_6.0	16	6,609,670 - 6,634,606 (+)	NCBI
Rnor_5.0	16	6,543,529 - 6,568,467 (+)	NCBI
RGSC_v3.4	16	5,908,759 - 5,933,695 (+)	RGD
Celera	16	9,440,328 - 9,465,209 (-)	RGD

Sequence:

show sequence

GAATTCGGGAATGTCATGGATCCAGTGAGACAGATCCAGTGCGACCGTGAAGGCAAACGCTTTCCGTTCCTCTCAGCTCCACCAGCTTCCACGTCCTCGCCCGACCGCGCCATGGAGGGTTACCATAA
GCCAGATCAGCAGAAGCTCCAGGCCCTGAAGGACACAGCCAATCGCCTGCGCATCAGCTCCATCCAGGCCACCACCGCGGCAGGCTCGGGACACCCCACATCATGCTGCAGCGCTGCCGAGATCATGG
CTGTCCTGTTTTTCCATACCATGCGCTACAAGGCCCTGGATCCCCGAAACCCTCACAATGATCGCTTTGTGCTCTCCAAGGGCCATGCAGCTCCCATCTTATATGCAGTCTGGGCTGAAGCTGGCTTC
CTGCCTGAGGCAGAGCTGCTGAACCTGAGGAAAATCAGCTCTGACTTGGATGGGCATCCTGTCCCGAAACAAGCCTTCACCGATGTGGCCACTGGCTCCCTGGGCCAGGGGCTGGGAGCTGCGTGCGG
GATGGCATACACAGGCAAATACTTCGACAAAGCCAGCTACCGAGTCTATTGCATGCTGGGAGACGGGGAGGTGTCCGAGGGCTCCGTTTGGGAGGCCATGGCCTTCGCTGGAATTTACAAGCTGGACA
ACCTCGTTGCCATTTTTGACATCAACCGTCTGGGCCAGAGCGACCCAGCCCCGCTGCAGCACCAAGTGGACGTCTACCAGAAGCGCTGTGAGGCCTTTGGCTGGCACGCCATCATCGTGGATGGGCAC
AGTGTGGAGGAGCTGTGCAAGGCCTTTGGTCAGGCCAAGCACCAACCAACAGCCATCATTGCCAAGACCTTCAAGGGCCGCGGGATCACAGGGATTGAAGACAAGGAGGCGTGGCATGGGAAGCCCCT
CCCCAAAAACATGGCTGAGCAGATTATCCAGGAGATTTACAGCCAGGTTCAGAGCAAAAAGAAGATCCTCGCCACGCCCCCTCAGGAGGATGCCCCTTCCGTGGACATTGCCAACATCCGAATGCCTA
CCCCACCCAACTACAAAGTGGGGGACAAGATAGCCACACGGAAAGCCTATGGATTGGCCCTTGCCAAGCTGGGCCACGCCAGTGACCGCATCATCGCCCTGGATGGAGACACCAAAAATTCCACCTTC
TCAGAGCTCTTCAAAAAGGAGCACCCAGACCGTTTCATCGAGTGCTACATTGCTGAGCAGAACATGGTGAGCATTGCTGTGGGCTGTGCCACACGTGACAGGACAGTGCCCTTCTGCAGCACTTTTGC
GGCCTTCTTCACACGCGCCTTCGACCAGATCCGCATGGCCGCCATCTCCGAGAGCAACATCAACCTTTGTGGCTCCCACTGCGGCGTGTCCATTGGGGAAGACGGGCCCTCGCAGATGGCCCTGGAAG
ACCTGGCCATGTTTCGGTCGGTCCCTATGTCCACCGTCTTTTACCCAAGTGATGGAGTTGCCACAGAGAAGGCAGTGGAATTAGCAGCCAATACAAAGGGCATCTGCTTCATTCGGACCAGCCGCCCA
GAAAATGCCATTATCTATAGCAACAACGAGGATTTCCAGGTTGGCCAAGCCAAGGTGGTCCTGAAGAGCAAGGACGACCAAGTGACAGTGATCGGGGCTGGCGTAACTCTGCACGAGGCTCTGGCTGC
TGCAGAGATGTTGAAGAAAGAGAAGATCGGTGTCCGTGTACTGGACCCCTTCACCATCAAGCCCCTGGACAAAAAGCTCATTCTCGACTGTGCCAGAGCAACCAAAGGCAGGATCCTCACCGTGGAGG
ACCACTACTATGAAGGTGGCATAGGCGAGGCAGTATCTGCTGTGGTAGTGGGCGAACCTGGAGTCACAGTCACTCGCCTGGCGGTCAGCCAAGTACCACGAAGTGGGAAGCCAGCTGAGCTGCTGAAG
ATGTTTGGTATTGACAAAGACGCCATTGTGCAAGCTGTGAAGGGCCTTGTCACCAAGGGCTAGGAAGGACATGGGATGCCGGGTGGGTGAACTACACATTCCAGGGATGTTCTGGCAAAGGTGCTCAA
GGGTGTACCGAGTGGAAAGGTAAATATATGTTTTGAGAAAAACCGAATTC

hide sequence

RefSeq Acc Id:

XM_006252661 ⟹ XP_006252723

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	5,729,381 - 5,755,170 (+)	NCBI
mRatBN7.2	16	5,724,347 - 5,748,702 (+)	NCBI
Rnor_6.0	16	6,610,253 - 6,634,608 (+)	NCBI
Rnor_5.0	16	6,543,529 - 6,568,467 (+)	NCBI

Sequence:

show sequence

TGATCCGCCCCCATGGGCGGGTCCTAAGGTGTCTTAACGCGCCCGCCCGCAGCACCGGGCCTCG
GTCACTGCCGGTCGCTTCCTGAGCCTCCTCTGGCTCTGTGTCTCTGTCCTCAGCTTCCACGTCCTCGCCCGACCGCGCCATGGAGGGTTACCATAAGCCAGATCAGCAGAAGCTCCAGGCCCTGAAGG
ACACAGCCAATCGCCTGCGCATCAGCTCCATCCAGGCCACCACCGCGGCAGGCTCGGGACACCCCACATCATGCTGCAGCGCTGCCGAGATCATGGCTGTCCTGTTTTTCCATACCATGCGCTACAAG
GCCCTGGATCCCCGAAACCCTCACAATGATCGCTTTGTGCTCTCCAAGGGCCATGCAGCTCCCATCTTATATGCAGTCTGGGCTGAAGCTGGCTTCCTGCCTGAGGCAGAGCTGCTGAACCTGAGGAA
AATCAGCTCTGACTTGGATGGGCATCCTGTCCCGAAACAAGCCTTCACCGATGTGGCCACTGGCTCCCTGGGCCAGGGGCTGGGAGCTGCGTGCGGGATGGCATACACAGGCAAATACTTCGACAAAG
CCAGCTACCGAGTCTATTGCATGCTGGGAGACGGGGAGGTGTCCGAGGGCTCCGTTTGGGAGGCCATGGCCTTCGCTGGAATTTACAAGCTGGACAACCTCGTTGCCATTTTTGACATCAACCGTCTG
GGCCAGAGCGACCCAGCCCCGCTGCAGCACCAAGTGGACGTCTACCAGAAGCGCTGTGAGGCCTTTGGCTGGCATGCCATCATCGTGGATGGGCACAGTGTGGAGGAGCTGTGCAAGGCCTTTGGTCA
GGCCAAGCACCAACCAACAGCCATCATTGCCAAGACCTTCAAGGGCCGCGGGATCACAGGGATTGAAGACAAGGAGGCGTGGCATGGGAAGCCCCTCCCCAAAAACATGGCTGAGCAGATTATCCAGG
AGATTTACAGCCAGGTTCAGAGCAAAAAGAAGATCCTCGCCACGCCCCCTCAGGAGGATGCCCCTTCCGTGGACATTGCCAACATCCGAATGCCTACCCCACCCAACTACAAAGTGGGGGACAAGATA
GCCACACGGAAAGCCTATGGATTGGCCCTTGCCAAGCTGGGCCACGCCAGTGACCGCATCATCGCCCTGGATGGAGACACCAAAAATTCCACCTTCTCAGAGCTCTTCAAAAAGGAGCACCCAGACCG
TTTCATCGAGTGCTACATTGCTGAGCAGAACATGGTGAGCATTGCTGTGGGCTGTGCCACACGTGACAGGACAGTGCCCTTCTGCAGCACTTTTGCGGCCTTCTTCACACGCGCCTTCGACCAGATCC
GCATGGCCGCCATCTCCGAGAGCAACATCAACCTCTGTGGCTCCCATTGCGGCGTGTCCATTGGGGAAGACGGGCCCTCGCAGATGGCCCTGGAAGACCTGGCCATGTTTCGGTCGGTCCCTATGTCC
ACCGTCTTTTACCCAAGTGATGGAGTTGCCACAGAGAAGGCAGTGGAATTAGCAGCCAATACAAAGGGCATCTGCTTCATTCGGACCAGCCGCCCAGAAAATGCCATTATCTATAGCAACAACGAGGA
TTTCCAGGTTGGCCAAGCCAAGGTGGTCCTGAAGAGCAAGGACGACCAAGTGACGGTGATCGGGGCTGGCGTAACTCTGCACGAGGCTCTGGCTGCTGCAGAGATGTTGAAGAAAGAGAAGATCGGCG
TCCGTGTACTGGACCCCTTCACCATCAAGCCCCTGGACAAAAAGCTCATTCTCGACTGTGCCAGAGCAACCAAAGGCAGGATCCTCACCGTGGAGGACCACTACTATGAAGGTGGCATAGGCGAGGCA
GTATCTGCTGCGGTAGTGGGCGAACCTGGAGTCACAGTCACTCGCCTGGCGGTCAGCCAAGTACCACGAAGTGGGAAGCCAGCTGAGCTGCTGAAGATGTTTGGTATTGACAAAGACGCCATTGTGCA
AGCTGTGAAGGGCCTTGTCACCAAGGGCTAGGAAGGACATGGGATGCCGGGTGGGTGAACTACACATTCCAGGGATGTTCTGGCAAAGGTGCTCAAGGGTGTACCGAGTGGAAAGGTAAATATATGTT
TTGAGAAAAAAATTAA

hide sequence


Protein RefSeqs	NP_001423670	(Get FASTA)	NCBI Sequence Viewer
	NP_001423671	(Get FASTA)	NCBI Sequence Viewer
	NP_001423672	(Get FASTA)	NCBI Sequence Viewer
	NP_072114	(Get FASTA)	NCBI Sequence Viewer
	XP_006252723	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA18026	(Get FASTA)	NCBI Sequence Viewer
	EDL88991	(Get FASTA)	NCBI Sequence Viewer
	EDL88992	(Get FASTA)	NCBI Sequence Viewer
	EDL88993	(Get FASTA)	NCBI Sequence Viewer
	EDL88994	(Get FASTA)	NCBI Sequence Viewer
	EDL88995	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000101850
	ENSRNOP00000104051
GenBank Protein	P50137	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_072114 ⟸ NM_022592

- UniProtKB:

A6KG34 (UniProtKB/TrEMBL), G3V826 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDPVRQIQCDREGKRFPFLSAPPASTSSPDRAMEGYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKALDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLPEAE
LLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLGQSDPAPLQHQVDVYQKRCEAFGWHAIIVDGHSVEEL
CKAFGQAKHQPTAIIAKTFKGRGITGIEDKEAWHGKPLPKNMAEQIIQEIYSQVQSKKKILATPPQEDAPSVDIANIRMPTPPNYKVGDKIATRKAYGLALAKLGHASDRIIALDGDTKNSTFSELFK
KEHPDRFIECYIAEQNMVSIAVGCATRDRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII
YSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAEMLKKEKIGVRVLDPFTIKPLDKKLILDCARATKGRILTVEDHYYEGGIGEAVSAVVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGID
KDAIVQAVKGLVTKG

hide sequence

RefSeq Acc Id:

XP_006252723 ⟸ XM_006252661

- Peptide Label:

isoform X1

- Sequence:

show sequence

MEGYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKALDPR
NPHNDRFVLSKGHAAPILYAVWAEAGFLPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLGQSDP
APLQHQVDVYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGIEDKEAWHGKPLPKNMAEQIIQEIYSQVQSKKKILATPPQEDAPSVDIANIRMPTPPNYKVGDKIATRKA
YGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHPDRFIECYIAEQNMVSIAVGCATRDRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYP
SDGVATEKAVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAEMLKKEKIGVRVLDPFTIKPLDKKLILDCARATKGRILTVEDHYYEGGIGEAVSAAV
VGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLVTKG

hide sequence

Ensembl Acc Id:

ENSRNOP00000021862 ⟸ ENSRNOT00000021862

Ensembl Acc Id:

ENSRNOP00000095976 ⟸ ENSRNOT00000113496

Ensembl Acc Id:

ENSRNOP00000104051 ⟸ ENSRNOT00000129190

Protein Domains

Transketolase N-terminal Transketolase-like pyrimidine-binding

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P50137-F1-model_v2	AlphaFold	P50137	1-623	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-12189	BioCyc
BioCyc Pathway	NONOXIPENT-PWY [pentose phosphate pathway (non-oxidative branch) I]	BioCyc
BioCyc Pathway Image	NONOXIPENT-PWY	BioCyc
Ensembl Genes	ENSRNOG00000016064	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000129190	ENTREZGENE
	ENSRNOT00000145038	ENTREZGENE
Gene3D-CATH	3.40.50.920	UniProtKB/Swiss-Prot
	3.40.50.970	UniProtKB/Swiss-Prot
InterPro	THDP-binding	UniProtKB/Swiss-Prot
	Transketo_C/PFOR_II	UniProtKB/Swiss-Prot
	Transketolase-like	UniProtKB/Swiss-Prot
	Transketolase-like_Pyr-bd	UniProtKB/Swiss-Prot
	Transketolase_BS	UniProtKB/Swiss-Prot
	Transketolase_C	UniProtKB/Swiss-Prot
	Transketolase_CS	UniProtKB/Swiss-Prot
	Transketolase_N	UniProtKB/Swiss-Prot
KEGG Report	rno:64524	UniProtKB/Swiss-Prot
NCBI Gene	64524	ENTREZGENE
PANTHER	TRANSKETOLASE	UniProtKB/Swiss-Prot
	TRANSKETOLASE	UniProtKB/Swiss-Prot
Pfam	Transket_pyr	UniProtKB/Swiss-Prot
	Transketolase_C	UniProtKB/Swiss-Prot
	Transketolase_N	UniProtKB/Swiss-Prot
PhenoGen	Tkt	PhenoGen
PROSITE	TRANSKETOLASE_1	UniProtKB/Swiss-Prot
	TRANSKETOLASE_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000016064	RatGTEx
SMART	Transket_pyr	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52518	UniProtKB/Swiss-Prot
	SSF52922	UniProtKB/Swiss-Prot
UniProt	A0A8I6AQ92	ENTREZGENE, UniProtKB/TrEMBL
	A6KG34	ENTREZGENE, UniProtKB/TrEMBL
	A6KG35_RAT	UniProtKB/TrEMBL
	A6KG36	ENTREZGENE, UniProtKB/TrEMBL
	A6KG37_RAT	UniProtKB/TrEMBL
	A6KG38_RAT	UniProtKB/TrEMBL
	G3V826	ENTREZGENE, UniProtKB/TrEMBL
	P50137	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-01-20	Tkt	transketolase			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Tkt	transketolase			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

BioCyc Pathways