Symbol:
Ran
Name:
RAN, member RAS oncogene family
RGD ID:
620367
Description:
Enables several functions, including dynein intermediate chain binding activity; guanyl ribonucleotide binding activity; and importin-alpha family protein binding activity. Involved in cellular response to mineralocorticoid stimulus; hippocampus development; and spermatid development. Located in male germ cell nucleus; manchette; and sperm flagellum. Part of nuclear pore. Used to study sciatic neuropathy. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human RAN (RAN, member RAS oncogene family); PARTICIPATES IN CRM1 export pathway; microRNA pathway; nuclear factor kappa B signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-bromopropane.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
GTP-binding nuclear protein Ran; GTPase Ran; ras-like protein TC4; ras-related nuclear protein
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
RAN (RAN, member RAS oncogene family)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Ran (RAN, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Ran (RAN, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
RAN (RAN, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
RAN (RAN, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ran (RAN, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
RAN (RAN, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
RAN (RAN, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Ran (RAN, member RAS oncogene family)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
KCTD7 (potassium channel tetramerization domain containing 7)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
RAN (RAN, member RAS oncogene family)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Mus musculus (house mouse):
Ran (RAN, member RAS oncogene family)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Danio rerio (zebrafish):
ran (RAN, member RAS oncogene family)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
GSP1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Ran
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
ran-1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
GSP2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
ran
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoInspector|PANTHER|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 12 33,311,155 - 33,314,339 (-) NCBI GRCr8 mRatBN7.2 12 27,674,049 - 27,678,598 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 12 27,674,050 - 27,678,276 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 12 28,814,245 - 28,817,373 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 12 29,424,809 - 29,427,937 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 12 28,483,802 - 28,486,937 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 12 31,319,556 - 31,324,105 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 12 31,320,624 - 31,323,810 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 12 33,245,991 - 33,250,540 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 12 28,736,786 - 28,739,921 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 12 28,600,176 - 28,603,309 (-) NCBI Celera 12 29,370,202 - 29,373,337 (-) NCBI Celera Cytogenetic Map 12 q13 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Ran Rat (+)-catechin multiple interactions ISO RAN (Homo sapiens) 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of RAN mRNA CTD PMID:24763279 Ran Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RAN mRNA] CTD PMID:31150632 Ran Rat (-)-epigallocatechin 3-gallate increases expression ISO RAN (Homo sapiens) 6480464 epigallocatechin gallate results in increased expression of RAN protein CTD PMID:31195006 Ran Rat (1->4)-beta-D-glucan multiple interactions ISO Ran (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RAN mRNA CTD PMID:36331819 Ran Rat 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o and p'-DDT affects the expression of RAN mRNA CTD PMID:17984292 Ran Rat 1,2-dichloroethane increases expression ISO Ran (Mus musculus) 6480464 ethylene dichloride results in increased expression of RAN mRNA CTD PMID:28960355 Ran Rat 1,2-dimethylhydrazine multiple interactions ISO Ran (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RAN mRNA CTD PMID:22206623 Ran Rat 1-bromopropane increases expression EXP 6480464 1-bromopropane results in increased expression of RAN protein CTD PMID:21925529 Ran Rat 1-bromopropane increases expression ISO Ran (Mus musculus) 6480464 1-bromopropane results in increased expression of RAN protein CTD PMID:27421776 Ran Rat 17alpha-ethynylestradiol increases expression ISO Ran (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of RAN mRNA CTD PMID:16174780 and PMID:19400957 Ran Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of RAN mRNA CTD PMID:16174780 more ... Ran Rat 17beta-estradiol affects expression ISO RAN (Homo sapiens) 6480464 Estradiol affects the expression of RAN mRNA CTD PMID:21826169 Ran Rat 17beta-estradiol increases expression ISO Ran (Mus musculus) 6480464 Estradiol results in increased expression of RAN mRNA CTD PMID:39298647 Ran Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of RAN mRNA CTD PMID:32145629 Ran Rat 17beta-estradiol multiple interactions ISO RAN (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RAN mRNA CTD PMID:20823114 Ran Rat 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Ran (Mus musculus) 6480464 2 more ... CTD PMID:30294300 Ran Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ran (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of RAN mRNA CTD PMID:21570461 Ran Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RAN mRNA CTD PMID:34747641 Ran Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Ran (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Ran Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of RAN mRNA CTD PMID:21346803 Ran Rat 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of RAN mRNA CTD PMID:21346803 Ran Rat 2-amino-14,16-dimethyloctadecan-3-ol decreases expression ISO RAN (Homo sapiens) 6480464 2-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of RAN protein CTD PMID:32044396 Ran Rat 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin analog results in decreased expression of RAN protein CTD PMID:26597043 Ran Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RAN (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RAN mRNA CTD PMID:28628672 Ran Rat 4,4'-sulfonyldiphenol increases expression ISO Ran (Mus musculus) 6480464 bisphenol S results in increased expression of RAN mRNA CTD PMID:39298647 Ran Rat 4,4'-sulfonyldiphenol increases expression ISO RAN (Homo sapiens) 6480464 bisphenol S results in increased expression of RAN protein CTD PMID:34186270 Ran Rat 4-hydroxyphenyl retinamide decreases expression ISO Ran (Mus musculus) 6480464 Fenretinide results in decreased expression of RAN mRNA CTD PMID:28973697 Ran Rat 5-aza-2'-deoxycytidine affects expression ISO Ran (Mus musculus) 6480464 Decitabine affects the expression of RAN mRNA CTD PMID:17524140 Ran Rat 5-aza-2'-deoxycytidine multiple interactions ISO Ran (Mus musculus) 6480464 [Decitabine co-treated with trichostatin A] results in decreased expression of RAN mRNA CTD PMID:17524140 Ran Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of RAN mRNA CTD PMID:30047161 Ran Rat 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:12376462 Ran Rat 8-Br-cAMP increases expression ISO RAN (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of RAN mRNA CTD PMID:22079614 Ran Rat aconitine decreases expression EXP 6480464 Aconitine results in decreased expression of RAN protein CTD PMID:33236894 Ran Rat actinomycin D multiple interactions ISO RAN (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of RAN protein CTD PMID:38460933 Ran Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of RAN mRNA CTD PMID:30047161 Ran Rat ammonium chloride increases expression EXP 6480464 Ammonium Chloride results in increased expression of RAN protein CTD PMID:16483693 Ran Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of RAN mRNA CTD PMID:16483693 Ran Rat amphetamine multiple interactions ISO Ran (Mus musculus) 6480464 MDK gene mutant form inhibits the reaction [Amphetamine results in increased expression of RAN protein] CTD PMID:23459167 Ran Rat amphetamine increases expression ISO Ran (Mus musculus) 6480464 Amphetamine results in increased expression of RAN protein CTD PMID:23459167 Ran Rat ampicillin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RAN protein CTD PMID:30545405 Ran Rat arsenite(3-) multiple interactions ISO RAN (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to RAN mRNA] CTD PMID:32406909 Ran Rat atrazine decreases expression ISO RAN (Homo sapiens) 6480464 Atrazine results in decreased expression of RAN mRNA CTD PMID:22378314 Ran Rat belinostat decreases expression ISO RAN (Homo sapiens) 6480464 belinostat results in decreased expression of RAN mRNA CTD PMID:19606018 Ran Rat benzo[a]pyrene increases expression ISO RAN (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of RAN protein CTD PMID:17292933 Ran Rat benzo[a]pyrene affects methylation ISO RAN (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of RAN promoter CTD PMID:27901495 Ran Rat benzo[a]pyrene increases methylation ISO RAN (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of RAN 3' UTR CTD PMID:27901495 Ran Rat benzo[a]pyrene increases expression ISO Ran (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of RAN mRNA CTD PMID:22228805 Ran Rat beta-lapachone increases expression ISO RAN (Homo sapiens) 6480464 beta-lapachone results in increased expression of RAN mRNA CTD PMID:38218311 Ran Rat bisphenol A affects expression ISO RAN (Homo sapiens) 6480464 bisphenol A affects the expression of RAN mRNA CTD PMID:21826169 and PMID:30903817 Ran Rat bisphenol A decreases expression ISO RAN (Homo sapiens) 6480464 bisphenol A results in decreased expression of RAN mRNA and bisphenol A results in decreased expression of RAN protein CTD PMID:29275510 and PMID:34186270 Ran Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of RAN gene CTD PMID:28505145 Ran Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of RAN mRNA CTD PMID:25181051 more ... Ran Rat bisphenol A decreases expression ISO Ran (Mus musculus) 6480464 bisphenol A results in decreased expression of RAN mRNA and bisphenol A results in decreased expression of RAN protein CTD PMID:26063408 and PMID:35999755 Ran Rat bisphenol AF increases expression ISO RAN (Homo sapiens) 6480464 bisphenol AF results in increased expression of RAN protein CTD PMID:34186270 Ran Rat Bisphenol B increases expression ISO RAN (Homo sapiens) 6480464 bisphenol B results in increased expression of RAN protein CTD PMID:34186270 Ran Rat bisphenol F multiple interactions ISO RAN (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RAN mRNA CTD PMID:28628672 Ran Rat bisphenol F increases expression ISO RAN (Homo sapiens) 6480464 bisphenol F results in increased expression of RAN protein CTD PMID:34186270 Ran Rat bisphenol F increases expression ISO Ran (Mus musculus) 6480464 bisphenol F results in increased expression of RAN mRNA CTD PMID:38685157 Ran Rat Brodifacoum increases expression EXP 6480464 bromfenacoum results in increased expression of RAN protein CTD PMID:28903499 Ran Rat bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of RAN mRNA CTD PMID:12628495 Ran Rat bucladesine multiple interactions ISO RAN (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RAN mRNA CTD PMID:20823114 Ran Rat buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of RAN mRNA CTD PMID:24136188 Ran Rat C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of RAN mRNA CTD PMID:19167457 Ran Rat cadmium atom multiple interactions ISO RAN (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RAN mRNA CTD PMID:35301059 Ran Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of RAN protein CTD PMID:21699967 Ran Rat cadmium dichloride multiple interactions ISO RAN (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RAN mRNA CTD PMID:35301059 Ran Rat caffeine increases expression ISO RAN (Homo sapiens) 6480464 Caffeine results in increased expression of RAN protein CTD PMID:31195006 Ran Rat carbon nanotube affects expression ISO RAN (Homo sapiens) 6480464 Nanotubes and Carbon affects the expression of RAN protein CTD PMID:22001959 Ran Rat carbon nanotube increases expression ISO Ran (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 Ran Rat carbon nanotube decreases expression ISO Ran (Mus musculus) 6480464 Nanotubes and Carbon analog results in decreased expression of RAN mRNA CTD PMID:25620056 Ran Rat chloropicrin increases expression ISO RAN (Homo sapiens) 6480464 chloropicrin results in increased expression of RAN mRNA CTD PMID:26352163 Ran Rat chromium(6+) affects expression ISO Ran (Mus musculus) 6480464 chromium hexavalent ion affects the expression of RAN mRNA CTD PMID:28472532 Ran Rat clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RAN mRNA CTD PMID:17602206 Ran Rat clopidogrel multiple interactions ISO Ran (Mus musculus) 6480464 clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of RAN mRNA] CTD PMID:19172522 Ran Rat clozapine decreases expression ISO RAN (Homo sapiens) 6480464 Clozapine results in decreased expression of RAN protein CTD PMID:34122009 Ran Rat copper(II) sulfate decreases expression ISO RAN (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of RAN mRNA CTD PMID:19549813 Ran Rat crocidolite asbestos affects expression ISO RAN (Homo sapiens) 6480464 Asbestos and Crocidolite affects the expression of RAN mRNA CTD PMID:17331233 Ran Rat crocidolite asbestos increases expression ISO RAN (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of RAN protein CTD PMID:29553831 Ran Rat dexamethasone multiple interactions ISO RAN (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RAN mRNA CTD PMID:28628672 Ran Rat Dibutyl phosphate affects expression ISO RAN (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of RAN mRNA CTD PMID:37042841 Ran Rat dibutyl phthalate decreases expression ISO Ran (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of RAN mRNA CTD PMID:21266533 Ran Rat dicrotophos decreases expression ISO RAN (Homo sapiens) 6480464 dicrotophos results in decreased expression of RAN mRNA CTD PMID:28302478 Ran Rat dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of RAN mRNA CTD PMID:16122865 Ran Rat dopamine increases expression EXP 6480464 Dopamine results in increased expression of RAN mRNA CTD PMID:21983523 Ran Rat doxorubicin decreases expression ISO RAN (Homo sapiens) 6480464 Doxorubicin results in decreased expression of RAN mRNA CTD PMID:29803840 Ran Rat ellagic acid decreases expression ISO RAN (Homo sapiens) 6480464 Ellagic Acid results in decreased expression of RAN mRNA CTD PMID:12002526 Ran Rat enzyme inhibitor multiple interactions ISO RAN (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RAN protein CTD PMID:23301498 Ran Rat ethanol affects localization EXP 6480464 Ethanol affects the localization of RAN protein CTD PMID:26185205 Ran Rat ethanol increases expression ISO Ran (Mus musculus) 6480464 Ethanol results in increased expression of RAN mRNA CTD PMID:30319688 Ran Rat fenoldopam increases expression EXP 6480464 Fenoldopam results in increased expression of RAN mRNA CTD PMID:21983523 Ran Rat finasteride increases expression EXP 6480464 Finasteride results in increased expression of RAN mRNA CTD PMID:24136188 Ran Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of RAN mRNA CTD PMID:24136188 Ran Rat folic acid multiple interactions ISO Ran (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RAN mRNA CTD PMID:22206623 Ran Rat folic acid decreases expression ISO Ran (Mus musculus) 6480464 Folic Acid results in decreased expression of RAN mRNA CTD PMID:25629700 Ran Rat FR900359 decreases phosphorylation ISO RAN (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of RAN protein CTD PMID:37730182 Ran Rat furan increases expression EXP 6480464 furan results in increased expression of RAN mRNA CTD PMID:22079235 and PMID:26194646 Ran Rat furfural multiple interactions ISO RAN (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of RAN protein CTD PMID:38598786 Ran Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of RAN mRNA CTD PMID:22061828 Ran Rat gentamycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RAN protein CTD PMID:30545405 Ran Rat glafenine increases expression EXP 6480464 Glafenine results in increased expression of RAN mRNA CTD PMID:24136188 Ran Rat hyaluronic acid multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of RAN protein] CTD PMID:23178681 Ran Rat hyaluronic acid decreases expression EXP 6480464 Hyaluronic Acid analog results in decreased expression of RAN protein CTD PMID:23178681 Ran Rat hydrogen peroxide affects expression ISO RAN (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of RAN protein CTD PMID:21179406 Ran Rat hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of RAN protein CTD PMID:23178681 Ran Rat hydrogen peroxide multiple interactions EXP 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of RAN protein] CTD PMID:23178681 Ran Rat hydroxyurea decreases expression ISO Ran (Mus musculus) 6480464 Hydroxyurea results in decreased expression of RAN mRNA CTD PMID:12929121 Ran Rat ibuprofen affects expression ISO RAN (Homo sapiens) 6480464 Ibuprofen affects the expression of RAN protein CTD PMID:18351690 Ran Rat indometacin multiple interactions ISO RAN (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RAN mRNA CTD PMID:28628672 Ran Rat inulin multiple interactions ISO Ran (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of RAN mRNA CTD PMID:36331819 Ran Rat ivermectin decreases expression ISO RAN (Homo sapiens) 6480464 Ivermectin results in decreased expression of RAN protein CTD PMID:32959892 Ran Rat L-ascorbic acid increases expression ISO Ran (Mus musculus) 6480464 Ascorbic Acid results in increased expression of RAN mRNA and Ascorbic Acid results in increased expression of RAN protein CTD PMID:22139585 Ran Rat lead(0) affects splicing ISO RAN (Homo sapiens) 6480464 Lead affects the splicing of RAN mRNA CTD PMID:28903495 Ran Rat lead(0) affects expression ISO RAN (Homo sapiens) 6480464 Lead affects the expression of RAN mRNA CTD PMID:28903495 Ran Rat linsidomine increases oxidation EXP 6480464 linsidomine results in increased oxidation of RAN protein CTD PMID:28086193 Ran Rat lipopolysaccharide multiple interactions ISO Ran (Mus musculus) 6480464 clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of RAN mRNA] CTD PMID:19172522 Ran Rat lithium atom increases expression EXP 6480464 Lithium results in increased expression of RAN protein CTD PMID:18296634 Ran Rat lithium hydride increases expression EXP 6480464 Lithium results in increased expression of RAN protein CTD PMID:18296634 Ran Rat medroxyprogesterone acetate multiple interactions ISO RAN (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RAN mRNA CTD PMID:20823114 Ran Rat methidathion affects expression ISO Ran (Mus musculus) 6480464 methidathion affects the expression of RAN mRNA CTD PMID:34813904 Ran Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of RAN mRNA CTD PMID:30047161 Ran Rat methotrexate affects expression ISO Ran (Mus musculus) 6480464 Methotrexate affects the expression of RAN mRNA CTD PMID:18502557 Ran Rat methyl methanesulfonate decreases expression ISO RAN (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of RAN mRNA CTD PMID:23649840 Ran Rat metronidazole multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RAN protein CTD PMID:30545405 Ran Rat monosodium L-glutamate increases expression ISO Ran (Mus musculus) 6480464 Sodium Glutamate results in increased expression of RAN mRNA CTD PMID:20111022 Ran Rat monosodium L-glutamate multiple interactions ISO Ran (Mus musculus) 6480464 [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of RAN mRNA CTD PMID:20111022 Ran Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RAN mRNA CTD PMID:17602206 Ran Rat N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of RAN mRNA CTD PMID:19638242 Ran Rat nefazodone increases expression EXP 6480464 nefazodone results in increased expression of RAN mRNA CTD PMID:24136188 Ran Rat neomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RAN protein CTD PMID:30545405 Ran Rat nickel atom increases expression ISO RAN (Homo sapiens) 6480464 Nickel results in increased expression of RAN mRNA CTD PMID:25583101 Ran Rat nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of RAN mRNA CTD PMID:22546817 Ran Rat nimesulide increases expression EXP 6480464 nimesulide results in increased expression of RAN mRNA CTD PMID:24136188 Ran Rat Nutlin-3 multiple interactions ISO RAN (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of RAN protein CTD PMID:38460933 Ran Rat ozone multiple interactions ISO Ran (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of RAN mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of RAN mRNA CTD PMID:34911549 Ran Rat paracetamol decreases expression ISO RAN (Homo sapiens) 6480464 Acetaminophen results in decreased expression of RAN mRNA CTD PMID:22230336 Ran Rat paraquat increases expression EXP 6480464 Paraquat results in increased expression of RAN mRNA CTD PMID:32680482 Ran Rat pentachlorophenol increases expression ISO Ran (Mus musculus) 6480464 Pentachlorophenol results in increased expression of RAN mRNA CTD PMID:23892564 Ran Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Ran (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RAN mRNA more ... CTD PMID:36331819 Ran Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of RAN mRNA CTD PMID:35163327 Ran Rat phenobarbital affects expression ISO Ran (Mus musculus) 6480464 Phenobarbital affects the expression of RAN mRNA CTD PMID:23091169 Ran Rat PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of RAN mRNA CTD PMID:12376462 and PMID:15215175 Ran Rat piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of RAN mRNA CTD PMID:22484513 Ran Rat pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of RAN mRNA CTD PMID:22484513 Ran Rat pirinixic acid increases expression ISO Ran (Mus musculus) 6480464 pirinixic acid results in increased expression of RAN mRNA CTD PMID:16221962 more ... Ran Rat pregnenolone 16alpha-carbonitrile multiple interactions ISO Ran (Mus musculus) 6480464 [1 more ... CTD PMID:23626729 Ran Rat progesterone decreases expression ISO RAN (Homo sapiens) 6480464 Progesterone results in decreased expression of RAN mRNA CTD PMID:18037150 Ran Rat propiconazole increases expression ISO Ran (Mus musculus) 6480464 propiconazole results in increased expression of RAN mRNA CTD PMID:19363144 Ran Rat propiconazole increases expression EXP 6480464 propiconazole results in increased expression of RAN mRNA CTD PMID:30047161 Ran Rat resveratrol decreases expression ISO RAN (Homo sapiens) 6480464 resveratrol results in decreased expression of RAN mRNA CTD PMID:12002526 and PMID:12569576 Ran Rat silicon dioxide affects secretion ISO RAN (Homo sapiens) 6480464 Silicon Dioxide analog affects the secretion of RAN protein CTD PMID:25895662 Ran Rat sodium arsenite increases expression ISO RAN (Homo sapiens) 6480464 sodium arsenite results in increased expression of RAN mRNA CTD PMID:24431212 and PMID:34032870 Ran Rat sodium arsenite decreases expression ISO RAN (Homo sapiens) 6480464 sodium arsenite results in decreased expression of RAN mRNA CTD PMID:38568856 Ran Rat sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of RAN protein CTD PMID:19072884 Ran Rat sodium arsenite increases expression ISO Ran (Mus musculus) 6480464 sodium arsenite results in increased expression of RAN mRNA CTD PMID:19822182 Ran Rat sodium chloride multiple interactions ISO RAN (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of RAN protein CTD PMID:38598786 Ran Rat sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of RAN mRNA CTD PMID:25993096 Ran Rat sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of RAN mRNA CTD PMID:30047161 Ran Rat tamoxifen increases expression ISO Ran (Mus musculus) 6480464 Tamoxifen results in increased expression of RAN mRNA CTD PMID:19400957 Ran Rat tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of RAN mRNA CTD PMID:19400957 Ran Rat tetrachloromethane increases expression ISO Ran (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of RAN mRNA CTD PMID:27339419 and PMID:31919559 Ran Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RAN mRNA] CTD PMID:31150632 Ran Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of RAN mRNA CTD PMID:31150632 Ran Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of RAN mRNA CTD PMID:16297948 more ... Ran Rat titanium dioxide increases expression ISO Ran (Mus musculus) 6480464 titanium dioxide results in increased expression of RAN mRNA CTD PMID:23557971 Ran Rat titanium dioxide increases methylation ISO Ran (Mus musculus) 6480464 titanium dioxide results in increased methylation of RAN gene CTD PMID:35295148 Ran Rat tolcapone affects binding EXP 6480464 tolcapone binds to RAN protein CTD PMID:19783845 Ran Rat triadimefon increases expression ISO Ran (Mus musculus) 6480464 triadimefon results in increased expression of RAN mRNA CTD PMID:19363144 Ran Rat trichloroethene multiple interactions ISO Ran (Mus musculus) 6480464 PPARA protein inhibits the reaction [Trichloroethylene results in increased expression of RAN protein] CTD PMID:15363585 Ran Rat trichloroethene increases expression ISO Ran (Mus musculus) 6480464 Trichloroethylene results in increased expression of RAN mRNA CTD PMID:15363585 and PMID:19448997 Ran Rat trichostatin A decreases expression ISO RAN (Homo sapiens) 6480464 trichostatin A results in decreased expression of RAN mRNA CTD PMID:19606018 Ran Rat trichostatin A multiple interactions ISO Ran (Mus musculus) 6480464 [decitabine co-treated with trichostatin A] results in decreased expression of RAN mRNA CTD PMID:17524140 Ran Rat trimellitic anhydride increases expression ISO Ran (Mus musculus) 6480464 trimellitic anhydride results in increased expression of RAN mRNA CTD PMID:19042947 Ran Rat troglitazone increases expression ISO Ran (Mus musculus) 6480464 troglitazone results in increased expression of RAN mRNA CTD PMID:28973697 Ran Rat trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of RAN mRNA CTD PMID:24136188 Ran Rat tungsten increases expression ISO Ran (Mus musculus) 6480464 Tungsten results in increased expression of RAN mRNA CTD PMID:30912803 Ran Rat tunicamycin decreases expression ISO RAN (Homo sapiens) 6480464 Tunicamycin results in decreased expression of RAN mRNA CTD PMID:22378314 Ran Rat uranium atom affects expression ISO RAN (Homo sapiens) 6480464 Uranium affects the expression of RAN mRNA CTD PMID:15672453 Ran Rat valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of RAN mRNA CTD PMID:24136188 Ran Rat valproic acid affects expression ISO Ran (Mus musculus) 6480464 Valproic Acid affects the expression of RAN mRNA CTD PMID:17292431 Ran Rat vancomycin decreases expression ISO Ran (Mus musculus) 6480464 Vancomycin results in decreased expression of RAN mRNA CTD PMID:18930951 Ran Rat vancomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RAN protein CTD PMID:30545405
Imported Annotations - KEGG (archival)
Imported Annotations - PID (archival)
(+)-catechin (ISO) (+)-schisandrin B (EXP) (-)-epigallocatechin 3-gallate (ISO) (1->4)-beta-D-glucan (ISO) 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (EXP) 1,2-dichloroethane (ISO) 1,2-dimethylhydrazine (ISO) 1-bromopropane (EXP,ISO) 17alpha-ethynylestradiol (EXP,ISO) 17beta-estradiol (EXP,ISO) 2,2',4,4'-Tetrabromodiphenyl ether (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 2,4-dinitrotoluene (EXP) 2,6-dinitrotoluene (EXP) 2-amino-14,16-dimethyloctadecan-3-ol (ISO) 3-chloropropane-1,2-diol (EXP) 3-isobutyl-1-methyl-7H-xanthine (ISO) 4,4'-sulfonyldiphenol (ISO) 4-hydroxyphenyl retinamide (ISO) 5-aza-2'-deoxycytidine (ISO) 6-propyl-2-thiouracil (EXP) 7,12-dimethyltetraphene (EXP) 8-Br-cAMP (ISO) aconitine (EXP) actinomycin D (ISO) amitrole (EXP) ammonium chloride (EXP) amphetamine (ISO) ampicillin (EXP) arsenite(3-) (ISO) atrazine (ISO) belinostat (ISO) benzo[a]pyrene (ISO) beta-lapachone (ISO) bisphenol A (EXP,ISO) bisphenol AF (ISO) Bisphenol B (ISO) bisphenol F (ISO) Brodifacoum (EXP) bromobenzene (EXP) bucladesine (ISO) buspirone (EXP) C60 fullerene (EXP) cadmium atom (ISO) cadmium dichloride (EXP,ISO) caffeine (ISO) carbon nanotube (ISO) chloropicrin (ISO) chromium(6+) (ISO) clofibric acid (EXP) clopidogrel (ISO) clozapine (ISO) copper(II) sulfate (ISO) crocidolite asbestos (ISO) dexamethasone (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (ISO) dicrotophos (ISO) dimethylarsinic acid (EXP) dopamine (EXP) doxorubicin (ISO) ellagic acid (ISO) enzyme inhibitor (ISO) ethanol (EXP,ISO) fenoldopam (EXP) finasteride (EXP) flutamide (EXP) folic acid (ISO) FR900359 (ISO) furan (EXP) furfural (ISO) gentamycin (EXP) glafenine (EXP) hyaluronic acid (EXP) hydrogen peroxide (EXP,ISO) hydroxyurea (ISO) ibuprofen (ISO) indometacin (ISO) inulin (ISO) ivermectin (ISO) L-ascorbic acid (ISO) lead(0) (ISO) linsidomine (EXP) lipopolysaccharide (ISO) lithium atom (EXP) lithium hydride (EXP) medroxyprogesterone acetate (ISO) methidathion (ISO) methimazole (EXP) methotrexate (ISO) methyl methanesulfonate (ISO) metronidazole (EXP) monosodium L-glutamate (ISO) N-nitrosodiethylamine (EXP) nefazodone (EXP) neomycin (EXP) nickel atom (ISO) nickel dichloride (EXP) nimesulide (EXP) Nutlin-3 (ISO) ozone (ISO) paracetamol (ISO) paraquat (EXP) pentachlorophenol (ISO) perfluorooctane-1-sulfonic acid (ISO) perfluorooctanoic acid (EXP) phenobarbital (ISO) PhIP (EXP) piperonyl butoxide (EXP) pirinixic acid (EXP,ISO) pregnenolone 16alpha-carbonitrile (ISO) progesterone (ISO) propiconazole (EXP,ISO) resveratrol (ISO) silicon dioxide (ISO) sodium arsenite (EXP,ISO) sodium chloride (ISO) sodium dichromate (EXP) sulfadimethoxine (EXP) tamoxifen (EXP,ISO) tetrachloromethane (EXP,ISO) thioacetamide (EXP) titanium dioxide (ISO) tolcapone (EXP) triadimefon (ISO) trichloroethene (ISO) trichostatin A (ISO) trimellitic anhydride (ISO) troglitazone (ISO) trovafloxacin (EXP) tungsten (ISO) tunicamycin (ISO) uranium atom (ISO) valdecoxib (EXP) valproic acid (ISO) vancomycin (EXP,ISO)
Biological Process
actin cytoskeleton organization (IEA,ISO) cell division (IEA) cellular response to mineralocorticoid stimulus (IEP) GTP metabolic process (IEA,ISO,ISS) hippocampus development (IEP) mitotic sister chromatid segregation (IEA,ISO,ISS) nucleocytoplasmic transport (IEA,TAS) positive regulation of protein export from nucleus (ISO) positive regulation of protein import into nucleus (IEA,ISO) protein export from nucleus (IEA,ISO,ISS,TAS) protein import into nucleus (IBA,IEA,ISO,ISS,TAS) protein localization (IEA,ISO) protein localization to nucleolus (IEA,ISO) protein transport (IEA) protein-containing complex localization (IEA,ISO) regulation of protein binding (IDA) ribosomal large subunit export from nucleus (IEA,ISO) ribosomal small subunit export from nucleus (IEA,ISO) ribosomal subunit export from nucleus (IBA) snRNA import into nucleus (IEA,ISO,ISS) spermatid development (IEP)
Cellular Component
centriole (IEA,ISO) chromatin (IEA,ISO) cytoplasm (IBA,IEA,ISO) cytosol (IEA) Flemming body (ISO) male germ cell nucleus (IDA) manchette (IDA) melanosome (IEA) midbody (IEA,ISO) nuclear envelope (IEA,ISO) nuclear pore (IDA) nucleolus (IEA,ISO) nucleoplasm (IEA,ISO) nucleus (IBA,IEA,ISO) protein-containing complex (IDA,IEA,ISO) recycling endosome (IEA,ISO) RISC complex (ISO) RNA nuclear export complex (IEA,ISO) sperm flagellum (IDA)
Molecular Function
dynein intermediate chain binding (IDA) G protein activity (IEA,ISO) GDP binding (IDA,IEA,ISO) GTP binding (IDA,IEA,ISO) GTPase activity (IBA,IEA,ISO,ISS,TAS) hydrolase activity (IEA) importin-alpha family protein binding (IDA) magnesium ion binding (IEA,ISO,ISS) metal ion binding (IEA) nuclear export signal receptor activity (ISO) nucleotide binding (IEA) pre-miRNA binding (IEA,ISO) protein binding (IPI,ISO) protein domain specific binding (IPI) protein heterodimerization activity (IEA,ISO) protein-containing complex binding (IPI) RISC complex binding (ISO)
1.
Separate binding sites on nuclear transport factor 2 (NTF2) for GDP-Ran and the phenylalanine-rich repeat regions of nucleoporins p62 and Nsp1p.
Clarkson WD, etal., J Mol Biol. 1996 Nov 8;263(4):517-24.
2.
RanGTP targets p97 to RanBP2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complex.
Delphin C, etal., Mol Biol Cell. 1997 Dec;8(12):2379-90.
3.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.
Vasopressin V1a receptor is required for nucleocytoplasmic transport of mineralocorticoid receptor.
Hori K, etal., Am J Physiol Renal Physiol. 2012 Oct;303(7):F1080-8. doi: 10.1152/ajprenal.00052.2012. Epub 2012 Jul 18.
5.
Ran, a GTP-binding protein involved in nucleocytoplasmic transport and microtubule nucleation, relocates from the manchette to the centrosome region during rat spermiogenesis.
Kierszenbaum AL, etal., Mol Reprod Dev 2002 Sep;63(1):131-40.
6.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
7.
Postage for the messenger: designating routes for nuclear mRNA export.
Natalizio BJ and Wente SR, Trends Cell Biol. 2013 Aug;23(8):365-73. doi: 10.1016/j.tcb.2013.03.006. Epub 2013 Apr 11.
8.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.
A high-resolution structure of the pre-microRNA nuclear export machinery.
Okada C, etal., Science. 2009 Nov 27;326(5957):1275-9.
10.
Gene expression profiling in the mammary gland of rats treated with 7,12-dimethylbenzanthracene.
Papaconstantinou AD, etal., Int J Cancer. 2006 Jan 1;118(1):17-24.
11.
Crystallographic and biochemical analysis of the Ran-binding zinc finger domain.
Partridge JR and Schwartz TU, J Mol Biol. 2009 Aug 14;391(2):375-89. Epub 2009 Jun 6.
12.
Molecular interactions between the importin alpha/beta heterodimer and proteins involved in vertebrate nuclear protein import.
Percipalle P, etal., J Mol Biol. 1997 Mar 7;266(4):722-32.
13.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
14.
PID Annotation Import Pipeline
Pipeline to import Pathway Interaction Database annotations from NCI into RGD
15.
GOA pipeline
RGD automated data pipeline
16.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
17.
Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus.
Shakib K, etal., Proteomics. 2005 Jul;5(11):2819-38.
18.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
19.
Changes of hippocampal signaling protein levels during postnatal brain development in the rat.
Weitzdorfer R, etal., Hippocampus. 2008;18(8):807-13.
20.
Essential role of the small GTPase Ran in postnatal pancreatic islet development.
Xia F, etal., PLoS One. 2011;6(11):e27879. doi: 10.1371/journal.pone.0027879. Epub 2011 Nov 17.
21.
Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve.
Yudin D, etal., Neuron. 2008 Jul 31;59(2):241-52. doi: 10.1016/j.neuron.2008.05.029.
22.
Nuclear export and cytoplasmic maturation of ribosomal subunits.
Zemp I and Kutay U, FEBS Lett. 2007 Jun 19;581(15):2783-93. Epub 2007 May 11.
23.
KRP3A and KRP3B: candidate motors in spermatid maturation in the seminiferous epithelium.
Zou Y, etal., Biol Reprod 2002 Mar;66(3):843-55.
Ran (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 12 33,311,155 - 33,314,339 (-) NCBI GRCr8 mRatBN7.2 12 27,674,049 - 27,678,598 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 12 27,674,050 - 27,678,276 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 12 28,814,245 - 28,817,373 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 12 29,424,809 - 29,427,937 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 12 28,483,802 - 28,486,937 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 12 31,319,556 - 31,324,105 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 12 31,320,624 - 31,323,810 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 12 33,245,991 - 33,250,540 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 12 28,736,786 - 28,739,921 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 12 28,600,176 - 28,603,309 (-) NCBI Celera 12 29,370,202 - 29,373,337 (-) NCBI Celera Cytogenetic Map 12 q13 NCBI
RAN (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 12 130,872,066 - 130,877,678 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 12 130,872,037 - 130,877,678 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 12 131,356,611 - 131,362,223 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 12 129,922,521 - 129,927,316 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 12 129,881,447 - 129,886,243 NCBI Celera 12 130,970,022 - 130,974,231 (+) NCBI Celera Cytogenetic Map 12 q24.33 NCBI HuRef 12 128,338,826 - 128,343,035 (+) NCBI HuRef CHM1_1 12 131,177,378 - 131,181,587 (+) NCBI CHM1_1 T2T-CHM13v2.0 12 130,911,164 - 130,916,776 (+) NCBI T2T-CHM13v2.0
Ran (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 5 129,097,264 - 129,101,388 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 5 129,097,133 - 129,101,387 (+) Ensembl GRCm39 Ensembl GRCm38 5 129,020,156 - 129,024,322 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 5 129,020,069 - 129,024,323 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 5 129,526,031 - 129,530,196 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 5 129,334,926 - 129,339,029 (+) NCBI MGSCv36 mm8 Celera 5 126,055,157 - 126,059,295 (+) NCBI Celera Cytogenetic Map 5 G1.3 NCBI cM Map 5 67.99 NCBI
Ran (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955482 1,220,876 - 1,224,395 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955482 1,222,944 - 1,223,891 (-) NCBI ChiLan1.0 ChiLan1.0
RAN (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 10 138,943,846 - 138,949,523 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 12 138,940,386 - 138,946,040 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 12 128,497,407 - 128,503,049 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 12 132,694,498 - 132,699,668 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 12 132,694,498 - 132,699,668 (+) Ensembl panpan1.1 panPan2
RAN (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 26 1,435,077 - 1,436,893 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 26 1,434,720 - 1,436,993 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 26 1,635,546 - 1,637,515 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 26 1,680,668 - 1,683,666 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 26 1,679,342 - 1,685,209 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 26 1,617,356 - 1,619,315 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 26 1,714,300 - 1,716,258 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 26 1,621,482 - 1,623,431 (-) NCBI UU_Cfam_GSD_1.0
Ran (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405118 123,047,105 - 123,050,801 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936660 1,668,956 - 1,672,067 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936660 1,669,352 - 1,673,972 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
RAN (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 14 24,311,577 - 24,317,789 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 14 24,312,810 - 24,318,024 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 14 25,861,945 - 25,865,060 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
RAN (Chlorocebus sabaeus - green monkey)
Ran (Heterocephalus glaber - naked mole-rat)
.
Assembly: RGSC_v3.4
Chromosome
Start Pos
End Pos
Reference Nucleotide
Variant Nucleotide
Variant Type
Strain
Variant Page
12
28737744
28737745
G
C
snv
FHH/EurMcwi (MCW) , BN/SsN (KNAW), SR/JrHsd (MCW), FHL/EurMcwi (MCW)
View more Information
12
28737953
28737954
C
A
snv
LCR/2Mco (UMich) , HCR/1Mco (UMich), COP/CrCrl (MCW & UW)
View more Information
12
28738034
28738035
T
C
snv
HCR/2Mco (UMich)
View more Information
12
28738041
28738042
C
T
snv
ACI/EurMcwi (MCW) , SS/JrHsdMcwi (MCW), BUF/N (KNAW), COP/CrCrl (MCW & UW), LEW/Crl (ICL), LEW/NCrl (ICL), SS/Jr (ICL), SS/JrHsdMcwi (ICL), HCR/1Mco (UMich), LCR/2Mco (UMich), HCR/2Mco (UMich), FHH/EurMcwi (MCW), FHL/EurMcwi (MCW), SR/JrHsd (MCW), SHRSP/Gcrc (MDC), ACI/N (KNAW), BN/SsN (KNAW), BN/NHsdMcwi (KNAW), F344/NRrrc (KNAW), LE/Stm (KNAW), M520/N (KNAW), MR/N (KNAW), WKY/N (KNAW), WN/N (KNAW), GH/OmrMcwi (MCW), BN-Lx/Cub (ICL), BN/NHsdMcwi (ICL), ACI/EurMcwi (ICL), BBDP/WorN (ICL), F344/NCrl (ICL), FHH/EurMcwi (ICL), FHL/EurMcwi (ICL), GK/Ox (ICL), LE/Stm (ICL), LH/MavRrrc (ICL), LL/MavRrrc (ICL), LN/MavRrrc (ICL), MHS/Gib (ICL), MNS/Gib (ICL), SBH/Ygl (ICL), SBN/Ygl (ICL), SHR/OlaIpcv (ICL), SHR/NHsd (ICL), SHRSP/Gcrc (ICL), SR/JrHsd (ICL), WAG/Rij (ICL), WKY/NCrl (ICL), WKY/Gcrc (ICL), WKY/NHsd (ICL), LCR/1Mco (UMich)
View more Information
12
28738068
28738069
G
A
snv
ACI/EurMcwi (MCW) , FHH/EurMcwi (MCW), LCR/2Mco (UMich), HCR/2Mco (UMich), LCR/1Mco (UMich), HCR/1Mco (UMich), GH/OmrMcwi (MCW), COP/CrCrl (MCW & UW), WN/N (KNAW), WKY/N (KNAW), MR/N (KNAW), FHL/EurMcwi (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), ACI/N (KNAW), BN/SsN (KNAW), BN/NHsdMcwi (KNAW), BUF/N (KNAW), F344/NRrrc (KNAW), LE/Stm (KNAW), M520/N (KNAW)
View more Information
12
28738103
28738104
A
G
snv
HCR/1Mco (UMich) , GH/OmrMcwi (MCW), COP/CrCrl (MCW & UW), SS/JrHsdMcwi (MCW), HCR/2Mco (UMich), FHL/EurMcwi (MCW), FHH/EurMcwi (MCW), ACI/EurMcwi (MCW), LCR/1Mco (UMich), SR/JrHsd (MCW)
View more Information
Assembly: Rnor_6.0
Chromosome
Start Pos
End Pos
Reference Nucleotide
Variant Nucleotide
Variant Type
Strain
Variant Page
12
31321578
31321579
G
C
snv
BN/SsN (MCW)
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12
31321875
31321876
C
T
snv
WN/N (MCW) , WKY/N (MCW), BN/SsN (MCW), M520/N (MCW), F344/NRrrc (MCW), Buf/N (MCW), ACI/N (MCW), MR/N (MCW)
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12
31321902
31321903
G
A
snv
WKY/N (MCW) , MR/N (MCW), M520/N (MCW), F344/NRrrc (MCW), Buf/N (MCW), BN/SsN (MCW), ACI/N (MCW), European Variation Archive Release 6, European Variation Archive Release 4, WN/N (MCW), European Variation Archive Release 3
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Predicted Target Of
Count of predictions: 60 Count of miRNA genes: 50 Interacting mature miRNAs: 53 Transcripts: ENSRNOT00000001247, ENSRNOT00000074908 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
631560 Apr1 Acute phase response QTL 1 6.1 orosomucoid 1 amount (VT:0010541) plasma orosomucoid 1 level (CMO:0001467) 12 19144362 46669029 Rat 8552964 Pigfal17 Plasma insulin-like growth factor 1 level QTL 17 3.5 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 12 5564495 46669029 Rat 8693635 Alc28 Alcohol consumption QTL 28 2.7 0.439 drinking behavior trait (VT:0001422) calculated ethanol drink intake rate (CMO:0001615) 12 23081340 44726024 Rat 61324 Eae5 Experimental allergic encephalomyelitis QTL 5 14 nervous system integrity trait (VT:0010566) percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402) 12 19610870 46669029 Rat 9590147 Scort7 Serum corticosterone level QTL 7 13.61 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 12 1 42110980 Rat 1549829 Scl48 Serum cholesterol level QTL 48 5 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 12 9603277 46669029 Rat 61331 Eau2 Experimental allergic uveoretinitis QTL 2 0.0005 uvea integrity trait (VT:0010551) experimental autoimmune uveitis score (CMO:0001504) 12 8525423 28064601 Rat 737822 Alc10 Alcohol consumption QTL 10 2.2 consumption behavior trait (VT:0002069) ethanol drink intake rate (CMO:0001407) 12 19610870 40218516 Rat 2293684 Bmd26 Bone mineral density QTL 26 4.4 0.0002 femur mineral mass (VT:0010011) total volumetric bone mineral density (CMO:0001728) 12 15872653 32974238 Rat 70169 Eae13 Experimental allergic encephalomyelitis QTL 13 0.032 nervous system integrity trait (VT:0010566) experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046) 12 24139202 36638073 Rat 1302792 Scl21 Serum cholesterol level QTL 21 3.8 0.0011 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 12 7196730 46669029 Rat 8693658 Alc33 Alcohol consumption QTL 33 2.1 0.68 drinking behavior trait (VT:0001422) calculated ethanol drink intake rate (CMO:0001615) 12 23081340 43551788 Rat 1598855 Bp294 Blood pressure QTL 294 3.5 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 12 1 34851688 Rat 1331761 Bp218 Blood pressure QTL 218 2.973 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 12 11073825 45055165 Rat 8694179 Bw150 Body weight QTL 150 2.9 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 12 1 42110980 Rat 1331763 Wbc2 White blood cell count QTL 2 3.162 leukocyte quantity (VT:0000217) total white blood cell count (CMO:0000365) 12 24234777 31894213 Rat 7411545 Bw128 Body weight QTL 128 5.2 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 12 1 42110980 Rat 7411547 Bw129 Body weight QTL 129 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 6 5564495 46669029 Rat 1300157 Rf21 Renal function QTL 21 4.4 renal blood flow trait (VT:2000006) absolute change in renal blood flow rate (CMO:0001168) 12 9318216 32103380 Rat 737979 Pia22 Pristane induced arthritis QTL 22 53.1 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 12 1 44465750 Rat 1298081 Cia25 Collagen induced arthritis QTL 25 4.7 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 12 19610889 35682913 Rat 2300186 Bmd59 Bone mineral density QTL 59 7.1 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 12 10474137 46669029 Rat 7411660 Foco28 Food consumption QTL 28 10.9 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 1 42110980 Rat 1331755 Bp219 Blood pressure QTL 219 3.041 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 12 11073825 28064557 Rat 70213 Niddm27 Non-insulin dependent diabetes mellitus QTL 27 3.72 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 12 19835789 38193007 Rat 7411641 Foco19 Food consumption QTL 19 27.7 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 5564495 46669029 Rat 7411643 Foco20 Food consumption QTL 20 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 20328819 46669029 Rat 5684888 Pia42 Pristane induced arthritis QTL 42 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 12 19610870 42828880 Rat 1549912 Bp268 Blood pressure QTL 268 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 10 13182736 46669029 Rat 2302060 Pia37 Pristane induced arthritis QTL 37 6.1 0.001 blood immunoglobulin amount (VT:0002460) serum immunoglobulin G1 level (CMO:0002115) 12 13198157 46669029 Rat 1641928 Alcrsp5 Alcohol response QTL 5 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 12 12812385 46669029 Rat 8552912 Pigfal6 Plasma insulin-like growth factor 1 level QTL 6 5 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 12 5564498 46669029 Rat 10059594 Kidm46 Kidney mass QTL 46 3.79 0.025 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 12 6107579 46669029 Rat 1581516 Cm56 Cardiac mass QTL 56 4.2 0.05 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 12 1 29333307 Rat 9590086 Insglur6 Insulin/glucose ratio QTL 6 18.97 0.001 blood insulin amount (VT:0001560) calculated plasma insulin level (CMO:0002170) 12 1 42110980 Rat 8552918 Pigfal7 Plasma insulin-like growth factor 1 level QTL 7 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 12 5564495 46669029 Rat 1549902 Bp269 Blood pressure QTL 269 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 12 13182736 46669029 Rat 61404 Bw120 Body weight QTL 120 5.1 body mass (VT:0001259) body mass index (BMI) (CMO:0000105) 12 12351619 46669029 Rat 2293699 Bss49 Bone structure and strength QTL 49 5.61 0.0001 lumbar vertebra size trait (VT:0010518) lumbar vertebra trabecular cross-sectional area (CMO:0001692) 12 10474137 46669029 Rat 634351 Apr5 Acute phase response QTL 5 6.7 blood interleukin-6 amount (VT:0008595) plasma interleukin-6 level (CMO:0001927) 12 1 44503507 Rat 634350 Apr4 Acute phase response QTL 4 6 orosomucoid 1 amount (VT:0010541) plasma orosomucoid 1 level (CMO:0001467) 12 1172005 46172005 Rat 61416 Pia4 Pristane induced arthritis QTL 4 8.4 joint integrity trait (VT:0010548) arthritic paw count (CMO:0001460) 12 13635523 30827399 Rat 7387292 Kidm42 Kidney mass QTL 42 3.03 0.0004 kidney mass (VT:0002707) left kidney wet weight (CMO:0000083) 12 1 36247923 Rat 61421 Cia12 Collagen induced arthritis QTL 12 4.6 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 12 13635523 35682913 Rat 2303569 Gluco44 Glucose level QTL 44 2 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 12 12812385 46669029 Rat 7411586 Foco5 Food consumption QTL 5 5.4 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 1 42110980 Rat 2303575 Insul14 Insulin level QTL 14 4 blood insulin amount (VT:0001560) blood insulin level (CMO:0000349) 12 1 42450532 Rat 7411588 Foco6 Food consumption QTL 6 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 5564495 46669029 Rat 2302042 Pia38 Pristane induced arthritis QTL 38 3.5 0.001 blood immunoglobulin amount (VT:0002460) serum immunoglobulin G1 level (CMO:0002115) 12 1 44503507 Rat 7411595 Foco9 Food consumption QTL 9 4 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 1 42110980 Rat 7411597 Foco10 Food consumption QTL 10 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 12 5564495 46669029 Rat 2293086 Iddm30 Insulin dependent diabetes mellitus QTL 30 3.82 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 12 8449490 28302290 Rat 631543 Bp83 Blood pressure QTL 83 5.8 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 12 15550826 38478808 Rat
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
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Ensembl Acc Id:
ENSRNOT00000001247 ⟹ ENSRNOP00000001247
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 12 27,674,050 - 27,678,276 (-) Ensembl Rnor_6.0 Ensembl 12 31,320,624 - 31,323,810 (-) Ensembl
RefSeq Acc Id:
NM_053439 ⟹ NP_445891
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 12 33,311,155 - 33,314,290 (-) NCBI mRatBN7.2 12 27,675,113 - 27,678,248 (-) NCBI Rnor_6.0 12 31,320,620 - 31,323,755 (-) NCBI Rnor_5.0 12 33,245,991 - 33,250,540 (-) NCBI RGSC_v3.4 12 28,736,786 - 28,739,921 (-) RGD Celera 12 29,370,202 - 29,373,337 (-) RGD
Sequence:
CATCTTTCCAGCTTCAGTCGGACAGGCGCGGAGACTCTTCTGGAAGCCGCTCTCTCCCGCAGGATCGCCGCGATGGCCGCCCAGGGAGAGCCGCAGGTCCAGTTCAAGCTCGTCCTGGTGGGCGACGG CGGCACCGGGAAGACGACGTTCGTGAAGCGCCACTTGACGGGCGAGTTTGAGAAGAAGTATGTAGCCACCCTGGGCGTGGAGGTGCACCCGCTCGTCTTCCATACCAACAGAGGACCCATCAAGTTCA ACGTGTGGGACACAGCCGGCCAGGAGAAGTTCGGGGGCCTGCGCGATGGCTACTACATCCAAGCCCAGTGTGCCATTATAATGTTTGACGTAACATCAAGAGTTACTTACAAGAACGTACCTAACTGG CATAGAGATCTGGTACGCGTGTGTGAAAACATCCCCATTGTATTGTGTGGCAACAAAGTGGATATTAAAGACAGGAAAGTGAAGGCAAAATCTATTGTCTTTCACCGAAAGAAGAATCTTCAGTACTA TGACATTTCTGCCAAAAGTAACTACAACTTTGAAAAGCCTTTCCTCTGGCTTGCCAGAAAGCTCATTGGAGATCCTAACTTGGAGTTCGTTGCCATGCCTGCTCTTGCCCCACCTGAGGTGGTCATGG ACCCAGCTTTGGCAGCACAGTACGAGCATGATTTAGAGGTTGCTCAGACGACTGCGCTCCCGGATGAGGATGACGACCTGTGAGAAAATGAAGCTGGAGCCCTGCGTCAGAAGTCTAGTTTTATAGGC AACTGTCCTGTGATGTCAGCGGTGCAGCGCGTGTGCCACCTTATTTAGCTAAGCAGATCGTGTACTTCATTGGGATGCTGAAAGATGAATGGGCTTCGAGTGAATGTGGCAGTTAAACATACCCGTCA TTTTTTGGACTTGCATATTTAGCTGTTTGGAACAGAGTTGTTTCCTTCCTGAATTTCAAAGATAAGACTGCTGCAGTCGCATCACAATATTCAGTGGTGAAATCTTGTTTGTTACTGTCATTCCCATT CTTTTCGTTTAGAATCAGAATAAAGTTGTATTTCAAATAATCTAAAAAAAAAAAAAAAAA
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RefSeq Acc Id:
XM_006249285 ⟹ XP_006249347
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 12 33,311,155 - 33,314,339 (-) NCBI mRatBN7.2 12 27,674,049 - 27,678,598 (-) NCBI Rnor_6.0 12 31,319,556 - 31,324,105 (-) NCBI Rnor_5.0 12 33,245,991 - 33,250,540 (-) NCBI
Sequence:
AGCAGCGCCCGCCTTTCCCGCCCACGAGGCCCGGACTAGGCCGCCGCCCGCGTGACGCGCGGCC TCCCGCAGTGAGCGCATGCGCGCGGGAGCCCGCGCTCAGAGCCGGCTCACGCGGACCTCCTGTTCTGGCTGCGTGCGCGTTCCCGCTCGCTCGTCTCACGTGACCCGCCGCACCTCTCCCGCCCTTGG CGCTCAGACCGACCGCCGAGTCGGACGGCTCAAGCGGACGTGCGCGTGCGCGCGCGCCGCGTGGTTGGGCGCGGCGCCGTTGCTCCGCCCCTTCTAGGCTCCTCCCCCTCCGCGCGCCGGCGTCCGCT GCGTCTCCGGCATTTGAATCGCGCTTCCGCCATCTTTCCAGCTTCAGTCGGACAGGCGCGGAGACTCTTCTGGAAGGATCGCCGCGATGGCCGCCCAGGGAGAGCCGCAGGTCCAGTTCAAGCTCGTC CTGGTGGGCGACGGCGGCACCGGGAAGACGACGTTCGTGAAGCGCCACTTGACGGGCGAGTTTGAGAAGAAGTATGTAGCCACCCTGGGCGTGGAGGTGCACCCGCTCGTCTTCCATACCAACAGAGG ACCCATCAAGTTCAACGTGTGGGACACAGCCGGCCAGGAGAAGTTCGGGGGCCTGCGCGATGGCTACTACATCCAAGCCCAGTGTGCCATTATAATGTTTGACGTAACATCAAGAGTTACTTACAAGA ACGTACCTAACTGGCATAGAGATCTGGTACGCGTGTGTGAAAACATCCCCATTGTATTGTGTGGCAACAAAGTGGATATTAAAGACAGGAAAGTGAAGGCAAAATCTATTGTCTTCCACCGAAAGAAG AATCTTCAGTACTATGACATTTCTGCCAAAAGTAACTACAACTTTGAAAAGCCTTTCCTCTGGCTTGCCAGAAAGCTCATTGGAGATCCTAACTTGGAGTTCGTTGCCATGCCTGCTCTTGCCCCACC TGAGGTGGTCATGGACCCAGCTTTGGCAGCACAGTACGAGCATGATTTAGAGGTTGCTCAGACGACTGCGCTCCCGGATGAGGATGACGACCTGTGAGAAAATGAAGCTGGAGCCCTGCGTCAGAAGT CTAGTTTTATAGGCAACTGTCCTGTGATGTCAGCGGTGCAGCGCGTGTGCCACCTTATTTAGCTAAGCAGATCGTGTACTTCATTGGGATGCTGAAAGATGAATGGGCTTCGAGTGAATGTGGCAGTT AAACATACCGTCATTTTTTGGACTTGCATATTTAGCTGTTTGGAACAGAGTTGTTTCCTTCCTGAATTTCAAAGATAAGACTGCTGCAGTCGCATCACAATATTCAGTGGTGAAATCTTGTTTGTTAC TGTCATTCCCATTCTTTTCGTTTAGAATCAGAATAAAGTTGTATTTCAAATAATCTAAACAAGTGAATCATCCCTTGTTTATAAGCATATTAAAACCGCTAACACGAGGGAGCTTGTGCCATAGTATG GTTTACAATGCTTTTGCTTCTTACCTGAAGTCTGTTCAGTTATGTTCTCCTTGTGCCTACCTTCATAAATATGGATTGTCATGTGATTCAGCTAGGATATCTGCCCTACCTGCATTTAGCCAGGTAGT TTAGTCTAAGGGAAGACCTTGTGTAAGACTGAAGATTTAAGTATGTACGTATCAGATGTTTAAGGATTATAGTTGACAATTTCTGTAACCTAGGCCTTCAGAAGTTAGAACTGCAGTTGGAAGCTTGA GGCTTTTCTGAGATGTGAGTACTCCATTCCATTTCCATGTCTAATGTTGGTTCTTTAAGATGTCCTTTGCTTTCGAATGGTGGCTCCTTCCTTGAGTGGTAGTCGCAGGAGGCAGAGGCAGGAGGGTC TCTTAAGTTGGCAGTCAACCTCGTCTCTACAGAGTCCTGTAGGTAGGCTGTTACCCTATAGTTTGTGCAGGAAAGGAAATGTTAGTGCTGCCCTGAAGAGTAGGGTGGGCTTCTCTGATGTGAAAGTG TGGGTTGAAACTTTATCTTGGGTGTGTGGTCCTGGCAGAACTGTGCTGTACTCAGATGTATTTATAGTAAGCCCTTCCATACGCTCTGCTGGCCAATCTACCAAAGTTCCTAAAAGGGTGGATACCTT TATATAGTTGGGGTTTTTCCCCCTCCAAAGAAGGTAGAGAGGAACACAATGGAGAAAGTGAGGAACCCGAAGCGTGCCCTAGCTTCAGCAGACTGATTTCAAGACTCAGTTTGATGTGTATGCTATGC TACAATCAGGTGAAGACCCTCTCTCTCCCCGGACTGGGATGAAACCTCATTTAGATGTCTTGAATTAATACAATGTGTGTAACGCTGGTACAGAATGTGGAACCTTCTAACTTTCTGACTTTTGTAAC AGTTAAATGGAGCTGCGTACGTGTGTTTAACCAGAGAACAGAGATTTACATTATTTATTGGAAGAACTTAAATATATATATCCTTTCTGCTTTGCCTCA
hide sequence
RefSeq Acc Id:
NP_445891 ⟸ NM_053439
- UniProtKB:
P62828 (UniProtKB/Swiss-Prot), A6J0S3 (UniProtKB/TrEMBL)
- Sequence:
MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD RKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
hide sequence
RefSeq Acc Id:
XP_006249347 ⟸ XM_006249285
- Peptide Label:
isoform X1
- UniProtKB:
P62828 (UniProtKB/Swiss-Prot), A6J0S3 (UniProtKB/TrEMBL)
- Sequence:
MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKD RKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
hide sequence
Ensembl Acc Id:
ENSRNOP00000001247 ⟸ ENSRNOT00000001247
RGD ID: 13698593
Promoter ID: EPDNEW_R9118
Type: initiation region
Name: Ran_1
Description: RAN, member RAS oncogene family
SO ACC ID: SO:0000170
Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ )
Experiment Methods: Single-end sequencing.
Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 12 31,323,770 - 31,323,830 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2004-09-10
Ran
RAN, member RAS oncogene family
Symbol and Name status set to approved
1299863
APPROVED
2002-08-07
Ran
RAN, member RAS oncogene family
Symbol and Name status set to provisional
70820
PROVISIONAL
Note Type
Note
Reference
gene_cellular_localization
localized to the manchette microtubules of elongating spermatids and later to the centrosome of maturing spermatids
727421