Ppp1r1a (protein phosphatase 1, regulatory (inhibitor) subunit 1A) - Rat Genome Database

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Gene: Ppp1r1a (protein phosphatase 1, regulatory (inhibitor) subunit 1A) Rattus norvegicus
Analyze
Symbol: Ppp1r1a
Name: protein phosphatase 1, regulatory (inhibitor) subunit 1A
RGD ID: 62018
Description: Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in intracellular signal transduction. Located in extracellular space. Orthologous to human PPP1R1A (protein phosphatase 1 regulatory inhibitor subunit 1A); PARTICIPATES IN long term potentiation; INTERACTS WITH 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: I-1; IPP-1; PP1 inhibitor 1; protein phosphatase 1 regulatory subunit 1A; protein phosphatase inhibitor 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87136,533,031 - 136,540,687 (-)NCBIGRCr8
mRatBN7.27134,654,578 - 134,662,236 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7134,654,579 - 134,662,230 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7136,410,417 - 136,418,114 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07138,639,788 - 138,647,485 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07138,625,389 - 138,633,131 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07145,146,480 - 145,154,131 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7145,146,481 - 145,154,131 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07142,925,730 - 142,933,709 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,428,730 - 142,436,381 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17142,508,919 - 142,516,570 (-)NCBI
Celera7131,078,656 - 131,086,307 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ppp1r1aRatCardiac Arrhythmias  ISOPPP1R1A (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20071777
Ppp1r1aRatcardiomyopathy  ISOPPP1R1A (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20071777
Ppp1r1aRatcongestive heart failure  ISOPPP1R1A (Homo sapiens)11554173CTD Direct Evidence: therapeuticCTDPMID:20071777
Ppp1r1aRathepatocellular carcinoma  ISOPPP1R1A (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15010824

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ppp1r1aRat1,1-dichloroethene decreases expressionISOPpp1r1a (Mus musculus)6480464vinylidene chloride results in decreased expression of PPP1R1A mRNACTDPMID:26682919
Ppp1r1aRat17alpha-ethynylestradiol multiple interactionsISOPpp1r1a (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPP1R1A mRNACTDPMID:17942748
Ppp1r1aRat17beta-estradiol decreases expressionISOPPP1R1A (Homo sapiens)6480464Estradiol results in decreased expression of PPP1R1A mRNACTDPMID:20106945
Ppp1r1aRat17beta-estradiol increases expressionISOPPP1R1A (Homo sapiens)6480464Estradiol results in increased expression of PPP1R1A mRNACTDPMID:36828454
Ppp1r1aRat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of PPP1R1A mRNACTDPMID:32145629
Ppp1r1aRat17beta-estradiol decreases expressionISOPpp1r1a (Mus musculus)6480464Estradiol results in decreased expression of PPP1R1A mRNACTDPMID:19484750
Ppp1r1aRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPPP1R1A (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of PPP1R1A mRNACTDPMID:20106945
Ppp1r1aRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPpp1r1a (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PPP1R1A mRNACTDPMID:21570461
Ppp1r1aRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPpp1r1a (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPP1R1A mRNACTDPMID:17942748
Ppp1r1aRat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Ppp1r1aRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOPPP1R1A (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PPP1R1A mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of PPP1R1A mRNACTDPMID:28628672
Ppp1r1aRat4,4'-sulfonyldiphenol decreases methylationISOPPP1R1A (Homo sapiens)6480464bisphenol S results in decreased methylation of PPP1R1A geneCTDPMID:31601247
Ppp1r1aRat4-hydroxyphenyl retinamide decreases expressionISOPpp1r1a (Mus musculus)6480464Fenretinide results in decreased expression of PPP1R1A mRNACTDPMID:28973697
Ppp1r1aRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PPP1R1A mRNACTDPMID:24780913
Ppp1r1aRat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of PPP1R1A mRNACTDPMID:30047161
Ppp1r1aRataflatoxin B1 affects expressionISOPPP1R1A (Homo sapiens)6480464Aflatoxin B1 affects the expression of PPP1R1A proteinCTDPMID:20106945
Ppp1r1aRataflatoxin B1 decreases expressionISOPPP1R1A (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of PPP1R1A mRNACTDPMID:22100608 and PMID:27153756
Ppp1r1aRataflatoxin B1 decreases methylationISOPPP1R1A (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of PPP1R1A geneCTDPMID:27153756
Ppp1r1aRatall-trans-retinoic acid decreases expressionISOPPP1R1A (Homo sapiens)6480464Tretinoin results in decreased expression of PPP1R1A mRNACTDPMID:21934132
Ppp1r1aRatalpha-Zearalanol decreases expressionEXP 6480464Zeranol results in decreased expression of PPP1R1A mRNACTDPMID:35163327

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Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ppp1r1aRatglycogen metabolic process involved_inIEAUniProtKB-KW:KW-03211600115GO_REF:0000043UniProtGO_REF:0000043
Ppp1r1aRatintracellular signal transduction involved_inIBAPANTHER:PTN000395915 and Ppp1r1b (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ppp1r1aRatsignal transduction involved_inIEAInterPro:IPR0084661600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ppp1r1aRatcytoplasm is_active_inIBAMGI:94860 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ppp1r1aRatextracellular space  IDA 7257523 RGD 

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ppp1r1aRatprotein binding enablesISOPPP1R1A (Homo sapiens)1624291UniProtKB:O75807 more ...RGDPMID:11564868 more ...
Ppp1r1aRatprotein binding enablesISOPpp1r1a (Mus musculus)1624291PR:P62137 PMID:14966518RGDPMID:14966518
Ppp1r1aRatprotein phosphatase inhibitor activity enablesIEAUniProtKB-KW:KW-06501600115GO_REF:0000043UniProtGO_REF:0000043
Ppp1r1aRatprotein phosphatase inhibitor activity enablesIEAInterPro:IPR0084661600115GO_REF:0000002InterProGO_REF:0000002

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ppp1r1aRatlong term potentiation  IEA 6907045 KEGGrno:04720

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#
Reference Title
Reference Citation
1. Detection and quantification of protein phosphatase inhibitor-1 gene expression in total rat liver and isolated hepatocytes. Aleem EA, etal., Mol Cell Biochem 2001 Jan;217(1-2):1-12.
2. Molecular cloning of protein phosphatase inhibitor-1 and its expression in rat and rabbit tissues. Elbrecht A, etal., J Biol Chem 1990 Aug 15;265(23):13415-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Potential of Protein Phosphatase Inhibitor 1 As Biomarker of Pancreatic beta-Cell Injury In Vitro and In Vivo. Jiang L, etal., Diabetes. 2013 Aug;62(8):2683-8. doi: 10.2337/db12-1507. Epub 2013 Apr 4.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
1 to 12 of 12 rows
PMID:15489334   PMID:16774736   PMID:19377265  



Ppp1r1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87136,533,031 - 136,540,687 (-)NCBIGRCr8
mRatBN7.27134,654,578 - 134,662,236 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7134,654,579 - 134,662,230 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7136,410,417 - 136,418,114 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07138,639,788 - 138,647,485 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07138,625,389 - 138,633,131 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07145,146,480 - 145,154,131 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7145,146,481 - 145,154,131 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07142,925,730 - 142,933,709 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,428,730 - 142,436,381 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17142,508,919 - 142,516,570 (-)NCBI
Celera7131,078,656 - 131,086,307 (-)NCBICelera
Cytogenetic Map7q36NCBI
PPP1R1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381254,579,246 - 54,588,659 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1254,575,387 - 54,588,659 (-)EnsemblGRCh38hg38GRCh38
GRCh371254,973,030 - 54,982,443 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361253,259,291 - 53,268,710 (-)NCBINCBI36Build 36hg18NCBI36
Build 341253,259,299 - 53,268,707NCBI
Celera1254,624,894 - 54,634,311 (-)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1252,011,832 - 52,016,913 (-)NCBIHuRef
CHM1_11254,939,731 - 54,949,148 (-)NCBICHM1_1
T2T-CHM13v2.01254,545,797 - 54,555,209 (-)NCBIT2T-CHM13v2.0
Ppp1r1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915103,438,706 - 103,446,465 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15103,438,706 - 103,446,430 (-)EnsemblGRCm39 Ensembl
GRCm3815103,530,279 - 103,538,027 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15103,530,279 - 103,538,003 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715103,360,710 - 103,368,423 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615103,358,313 - 103,365,995 (-)NCBIMGSCv36mm8
Celera15105,688,277 - 105,695,984 (-)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1559.01NCBI
Ppp1r1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554581,819,366 - 1,823,867 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554581,819,366 - 1,823,864 (-)NCBIChiLan1.0ChiLan1.0
PPP1R1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21039,586,156 - 39,594,552 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11239,582,925 - 39,591,321 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01234,158,956 - 34,167,350 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11234,887,168 - 34,896,360 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1234,882,975 - 34,898,218 (+)Ensemblpanpan1.1panPan2
PPP1R1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.127766,757 - 770,994 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl27766,338 - 771,598 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2745,482,576 - 45,490,666 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.027761,676 - 770,078 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl27761,653 - 770,038 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.127754,299 - 762,405 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.027762,376 - 770,488 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02745,886,785 - 45,894,624 (-)NCBIUU_Cfam_GSD_1.0
Ppp1r1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494561,389,455 - 61,397,676 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651211,767,172 - 11,775,573 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651211,765,769 - 11,775,573 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl519,753,847 - 19,763,269 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1519,753,850 - 19,763,281 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PPP1R1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11150,695,896 - 50,704,191 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1150,696,032 - 50,704,219 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037195,332,472 - 195,341,778 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249042,608,895 - 2,617,543 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249042,608,891 - 2,617,202 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Ppp1r1a
27 total Variants

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:102
Interacting mature miRNAs:118
Transcripts:ENSRNOT00000055271
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat

1 to 10 of 12 rows
RH127463  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27134,654,201 - 134,654,408 (+)MAPPERmRatBN7.2
Rnor_6.07145,146,104 - 145,146,310NCBIRnor6.0
Rnor_5.07142,925,354 - 142,925,560UniSTSRnor5.0
RGSC_v3.47142,428,354 - 142,428,560UniSTSRGSC3.4
Celera7131,078,280 - 131,078,486UniSTS
RH 3.4 Map71063.5UniSTS
Cytogenetic Map7q36UniSTS
RH130620  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27134,654,856 - 134,655,051 (+)MAPPERmRatBN7.2
Rnor_6.07145,146,759 - 145,146,953NCBIRnor6.0
Rnor_5.07142,926,009 - 142,926,203UniSTSRnor5.0
RGSC_v3.47142,429,009 - 142,429,203UniSTSRGSC3.4
Celera7131,078,935 - 131,079,129UniSTS
RH 3.4 Map71063.5UniSTS
Cytogenetic Map7q36UniSTS
AA997855  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr87136,533,875 - 136,534,432 (+)Marker Load Pipeline
mRatBN7.27134,655,422 - 134,655,979 (+)MAPPERmRatBN7.2
Rnor_6.07145,147,325 - 145,147,881NCBIRnor6.0
Rnor_5.07142,926,575 - 142,927,131UniSTSRnor5.0
RGSC_v3.47142,429,575 - 142,430,131UniSTSRGSC3.4
Celera7131,079,501 - 131,080,057UniSTS
RH 3.4 Map71064.9UniSTS
Cytogenetic Map7q36UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 83 82 51 25 51 6 210 97 93 45 55 31



Ensembl Acc Id: ENSRNOT00000055271   ⟹   ENSRNOP00000052146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7134,654,579 - 134,662,229 (-)Ensembl
Rnor_6.0 Ensembl7145,146,481 - 145,154,131 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105860   ⟹   ENSRNOP00000079380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7134,655,776 - 134,662,230 (-)Ensembl
RefSeq Acc Id: NM_022676   ⟹   NP_073167
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87136,533,031 - 136,540,682 (-)NCBI
mRatBN7.27134,654,578 - 134,662,229 (-)NCBI
Rnor_6.07145,146,480 - 145,154,131 (-)NCBI
Rnor_5.07142,925,730 - 142,933,709 (-)NCBI
RGSC_v3.47142,428,730 - 142,436,381 (-)RGD
Celera7131,078,656 - 131,086,307 (-)RGD
Sequence:
RefSeq Acc Id: XM_006242437   ⟹   XP_006242499
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87136,533,829 - 136,540,687 (-)NCBI
mRatBN7.27134,654,813 - 134,662,236 (-)NCBI
Rnor_6.07145,147,278 - 145,154,105 (-)NCBI
Rnor_5.07142,925,730 - 142,933,709 (-)NCBI
Sequence:
RefSeq Acc Id: NP_073167   ⟸   NM_022676
- UniProtKB: Q6DSU5 (UniProtKB/Swiss-Prot),   P19103 (UniProtKB/Swiss-Prot),   A6KD17 (UniProtKB/TrEMBL),   A6KD15 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242499   ⟸   XM_006242437
- Peptide Label: isoform X1
- UniProtKB: A6KD15 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000052146   ⟸   ENSRNOT00000055271
Ensembl Acc Id: ENSRNOP00000079380   ⟸   ENSRNOT00000105860

Name Modeler Protein Id AA Range Protein Structure
AF-P19103-F1-model_v2 AlphaFold P19103 1-171 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695720
Promoter ID:EPDNEW_R6245
Type:initiation region
Name:Ppp1r1a_1
Description:protein phosphatase 1, regulatory subunit 1A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07145,154,131 - 145,154,191EPDNEW


1 to 22 of 22 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-31867 BioCyc
Ensembl Genes ENSRNOG00000036827 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000055271 ENTREZGENE
  ENSRNOT00000055271.3 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7127505 IMAGE-MGC_LOAD
InterPro PPP1R1A/B/C UniProtKB/Swiss-Prot
KEGG Report rno:58977 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93431 IMAGE-MGC_LOAD
NCBI Gene 58977 ENTREZGENE
PANTHER PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1A UniProtKB/Swiss-Prot
  PTHR15417 UniProtKB/Swiss-Prot
Pfam DARPP-32 UniProtKB/Swiss-Prot
PhenoGen Ppp1r1a PhenoGen
RatGTEx ENSRNOG00000036827 RatGTEx
UniProt A0A8I6G585_RAT UniProtKB/TrEMBL
  A6KD14_RAT UniProtKB/TrEMBL
  A6KD15 ENTREZGENE, UniProtKB/TrEMBL
  A6KD16_RAT UniProtKB/TrEMBL
  A6KD17 ENTREZGENE, UniProtKB/TrEMBL
  P19103 ENTREZGENE, UniProtKB/Swiss-Prot
  Q6DSU5 ENTREZGENE
UniProt Secondary Q6DSU5 UniProtKB/Swiss-Prot
1 to 22 of 22 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ppp1r1a  protein phosphatase 1, regulatory (inhibitor) subunit 1A       Name updated 70584 APPROVED

Note Type Note Reference
gene_regulation may be threonine phosphorylated by cAMP-dependent protein kinase 61702