Stambp (Stam binding protein) - Rat Genome Database

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Gene: Stambp (Stam binding protein) Rattus norvegicus
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Symbol: Stambp
Name: Stam binding protein
RGD ID: 619963
Description: Predicted to enable K63-linked deubiquitinase activity and protein domain specific binding activity. Predicted to be involved in negative regulation of Ras protein signal transduction and negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to act upstream of or within mitotic cytokinesis; negative regulation of hippocampal neuron apoptotic process; and protein deubiquitination. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cleavage furrow and endosome. Orthologous to human STAMBP (STAM binding protein); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; endocytosis pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Amsh; associated molecule with the SH3 domain of STAM; STAM-binding protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,613,730 - 117,642,163 (-)NCBIGRCr8
mRatBN7.24116,055,563 - 116,083,563 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4116,056,057 - 116,080,543 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,534,816 - 121,559,301 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04117,309,987 - 117,334,471 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04115,923,556 - 115,948,037 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04115,249,343 - 115,277,340 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4115,249,351 - 115,275,068 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04179,839,851 - 179,867,468 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,766,905 - 117,791,399 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14118,011,387 - 118,035,880 (-)NCBI
Celera4105,049,309 - 105,073,789 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
StambpRatcongenital disorder of glycosylation type IIb  ISOSTAMBP (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital disorder of glycosylation type 2BClinVarPMID:24716661 more ...
StambpRatdystonia  ISOSTAMBP (Homo sapiens)8554872ClinVar Annotator: match by term: DystoniaClinVarPMID:16697227 more ...
StambpRatgenetic disease  ISOSTAMBP (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
StambpRatMethylmalonyl-CoA Epimerase Deficiency  ISOSTAMBP (Homo sapiens)8554872ClinVar Annotator: match by term: METHYLMALONIC ACIDURIA IIIClinVarPMID:16697227 more ...
StambpRatMicrocephaly-Capillary Malformation Syndrome  ISOSTAMBP (Homo sapiens)8554872ClinVar more ...ClinVarPMID:18414213 more ...
Object Symbol
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Original Reference(s)
StambpRatbrain disease  ISOSTAMBP (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23542699
StambpRatCapillary Malformation-Arteriovenous Malformation  ISOSTAMBP (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23542699
StambpRatDevelopmental Disabilities  ISOSTAMBP (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23542699
StambpRatepilepsy  ISOSTAMBP (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23542699
StambpRatmicrocephaly  ISOSTAMBP (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23542699
Object Symbol
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Original Reference(s)
StambpRatMicrocephaly-Capillary Malformation Syndrome  ISOSTAMBP (Homo sapiens)7240710 OMIM 

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Original Reference(s)
StambpRat1,2-dimethylhydrazine decreases expressionISOStambp (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of STAMBP mRNACTDPMID:22206623
StambpRat1,3-dinitrobenzene decreases expressionEXP 64804643-dinitrobenzene results in decreased expression of STAMBP mRNACTDPMID:21983209
StambpRat17alpha-ethynylestradiol increases expressionISOStambp (Mus musculus)6480464Ethinyl Estradiol results in increased expression of STAMBP mRNACTDPMID:17942748
StambpRat17alpha-ethynylestradiol multiple interactionsISOStambp (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of STAMBP mRNACTDPMID:17942748
StambpRat17alpha-ethynylestradiol affects expressionISOStambp (Mus musculus)6480464Ethinyl Estradiol affects the expression of STAMBP mRNACTDPMID:17555576
StambpRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOStambp (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of STAMBP mRNACTDPMID:17942748
StambpRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of STAMBP mRNACTDPMID:32109520 and PMID:33387578
StambpRat2-hydroxypropanoic acid decreases expressionISOSTAMBP (Homo sapiens)6480464Lactic Acid results in decreased expression of STAMBP mRNACTDPMID:30851411
StambpRat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of STAMBP proteinCTDPMID:34915118
StambpRat4,4'-diaminodiphenylmethane decreases expressionISOStambp (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of STAMBP mRNACTDPMID:18648102
StambpRat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of STAMBP mRNACTDPMID:36041667
StambpRat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of STAMBP mRNACTDPMID:24780913
StambpRatacetylsalicylic acid increases expressionISOSTAMBP (Homo sapiens)6480464Aspirin results in increased expression of STAMBP mRNACTDPMID:15928584
StambpRatacrolein multiple interactionsISOSTAMBP (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased oxidation of STAMBP mRNACTDPMID:32845096
StambpRatacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of STAMBP mRNACTDPMID:28959563
StambpRataflatoxin B1 increases expressionISOSTAMBP (Homo sapiens)6480464Aflatoxin B1 results in increased expression of STAMBP mRNACTDPMID:22100608
StambpRatamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of STAMBP mRNACTDPMID:30047161
StambpRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of STAMBP mRNACTDPMID:16483693
StambpRatarsenite(3-) multiple interactionsISOSTAMBP (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to STAMBP mRNA]CTDPMID:32406909
StambpRatbeta-lapachone increases expressionISOSTAMBP (Homo sapiens)6480464beta-lapachone results in increased expression of STAMBP mRNACTDPMID:38218311

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Biological Process
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Original Reference(s)
StambpRatbiological_process  ND 159840702/2009: no relevant rat dataRGD 
StambpRathippocampal neuron apoptotic process acts_upstream_ofIEAUniProtKB:Q9CQ26 and ensembl:ENSMUSP000000708761600115GO_REF:0000107EnsemblGO_REF:0000107
StambpRathippocampal neuron apoptotic process acts_upstream_ofISOStambp (Mus musculus)1624291MGI:2180168 PMID:11713295RGDPMID:11713295
StambpRatmitotic cytokinesis acts_upstream_of_or_withinISOSTAMBP (Homo sapiens)1624291 PMID:18388320RGDPMID:18388320
StambpRatnegative regulation of hippocampal neuron apoptotic process acts_upstream_of_or_withinISOStambp (Mus musculus)1624291MGI:2180168 PMID:11713295RGDPMID:11713295
StambpRatnegative regulation of hippocampal neuron apoptotic process acts_upstream_of_or_withinIEAUniProtKB:Q9CQ26 and ensembl:ENSMUSP000000708761600115GO_REF:0000107EnsemblGO_REF:0000107
StambpRatnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction involved_inISOSTAMBP (Homo sapiens)1624291 PMID:23542699RGDPMID:23542699
StambpRatnegative regulation of Ras protein signal transduction involved_inISOSTAMBP (Homo sapiens)1624291 PMID:23542699RGDPMID:23542699
StambpRatnegative regulation of Ras protein signal transduction involved_inIBAPANTHER:PTN002658515 and UniProtKB:O956301600115GO_REF:0000033GO_CentralGO_REF:0000033
StambpRatprotein deubiquitination acts_upstream_of_or_withinISOStambp (Mus musculus)1624291MGI:2180168 PMID:21531206RGDPMID:21531206
StambpRatprotein deubiquitination involved_inIEAARBA:ARBA000278791600115GO_REF:0000117UniProtGO_REF:0000117
StambpRatprotein deubiquitination involved_inIEAInterPro:IPR0440981600115GO_REF:0000002InterProGO_REF:0000002
StambpRatprotein deubiquitination acts_upstream_of_or_withinIEAUniProtKB:Q9CQ26 and ensembl:ENSMUSP000000708761600115GO_REF:0000107EnsemblGO_REF:0000107
StambpRatprotein deubiquitination acts_upstream_of_or_withinISOSTAMBP (Homo sapiens)1624291 PMID:18388320RGDPMID:18388320
StambpRatprotein K63-linked deubiquitination involved_inIEAInterPro:IPR0440981600115GO_REF:0000002InterProGO_REF:0000002
StambpRatproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
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Cellular Component
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Object Symbol
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Original Reference(s)
StambpRatcleavage furrow located_inISOSTAMBP (Homo sapiens)1624291 PMID:18388320RGDPMID:18388320
StambpRatcleavage furrow located_inIEAUniProtKB:Q9CQ26 and ensembl:ENSMUSP000000708761600115GO_REF:0000107EnsemblGO_REF:0000107
StambpRatcleavage furrow is_active_inIBAMGI:1917777 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
StambpRatcleavage furrow located_inISOStambp (Mus musculus)1624291 PMID:18388320RGDPMID:18388320
StambpRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
StambpRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
StambpRatcytosol located_inISOSTAMBP (Homo sapiens) more ...1624291 RGDGO_REF:0000052
StambpRatearly endosome located_inIEAUniProtKB-SubCell:SL-00941600115GO_REF:0000044UniProtGO_REF:0000044
StambpRatendosome located_inIEAUniProtKB-KW:KW-09671600115GO_REF:0000043UniProtGO_REF:0000043
StambpRatendosome is_active_inIBAPANTHER:PTN000310308 and UniProtKB:Q5PNU31600115GO_REF:0000033GO_CentralGO_REF:0000033
StambpRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
StambpRatmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
StambpRatnucleoplasm located_inISOSTAMBP (Homo sapiens) more ...1624291 RGDGO_REF:0000052
StambpRatnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
StambpRatnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
StambpRatplasma membrane located_inISOSTAMBP (Homo sapiens) more ...1624291 RGDGO_REF:0000052
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Molecular Function
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Object Symbol
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Original Reference(s)
StambpRatdeubiquitinase activity enablesISOSTAMBP (Homo sapiens)1624291 PMID:18388320RGDPMID:18388320
StambpRathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
StambpRatK63-linked deubiquitinase activity enablesISSUniProtKB:O956301600115GO_REF:0000024UniProtGO_REF:0000024
StambpRatK63-linked deubiquitinase activity enablesIEAInterPro:IPR0440981600115GO_REF:0000002InterProGO_REF:0000002
StambpRatK63-linked deubiquitinase activity enablesIBAPANTHER:PTN000310309 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
StambpRatK63-linked deubiquitinase activity enablesISOSTAMBP (Homo sapiens)1624291 PMID:34425109RGDPMID:34425109
StambpRatmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
StambpRatmetal-dependent deubiquitinase activity enablesIEAInterPro:IPR0440981600115GO_REF:0000002InterProGO_REF:0000002
StambpRatmetallopeptidase activity enablesIEAInterPro:IPR0005551600115GO_REF:0000002InterProGO_REF:0000002
StambpRatmetallopeptidase activity enablesIEAUniProtKB-KW:KW-04821600115GO_REF:0000043UniProtGO_REF:0000043
StambpRatpeptidase activity enablesIEAInterPro:IPR0005551600115GO_REF:0000002InterProGO_REF:0000002
StambpRatpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
StambpRatprotein binding enablesISOSTAMBP (Homo sapiens)1624291UniProtKB:O43541-2 more ...RGDPMID:10383417 more ...
StambpRatprotein domain specific binding enablesISOSTAMBP (Homo sapiens)1624291UniProtKB:Q9Y3E7 and PMID:18395747RGDPMID:18395747
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RGD Manual Annotations


  
Object Symbol
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Source
Original Reference(s)
StambpRatBone morphogenetic proteins signaling pathway  ISS 1549422 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
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Reference
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Source
Original Reference(s)
StambpRatendocytosis pathway  IEA 6907045 KEGGrno:04144

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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads. Itoh F, etal., EMBO J 2001 Aug 1;20(15):4132-42.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
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PMID:11713295   PMID:15489334   PMID:18388320   PMID:18395747   PMID:19056867   PMID:21531206   PMID:23533145   PMID:23542699   PMID:37591460  



Stambp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,613,730 - 117,642,163 (-)NCBIGRCr8
mRatBN7.24116,055,563 - 116,083,563 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4116,056,057 - 116,080,543 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,534,816 - 121,559,301 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04117,309,987 - 117,334,471 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04115,923,556 - 115,948,037 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04115,249,343 - 115,277,340 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4115,249,351 - 115,275,068 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04179,839,851 - 179,867,468 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,766,905 - 117,791,399 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14118,011,387 - 118,035,880 (-)NCBI
Celera4105,049,309 - 105,073,789 (-)NCBICelera
Cytogenetic Map4q34NCBI
STAMBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38273,828,961 - 73,873,656 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl273,828,916 - 73,873,659 (+)EnsemblGRCh38hg38GRCh38
GRCh37274,056,088 - 74,100,783 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36273,909,594 - 73,943,519 (+)NCBINCBI36Build 36hg18NCBI36
Celera273,887,352 - 73,921,265 (+)NCBICelera
Cytogenetic Map2p13.1NCBI
HuRef273,791,345 - 73,829,114 (+)NCBIHuRef
CHM1_1273,985,403 - 74,023,636 (+)NCBICHM1_1
T2T-CHM13v2.0273,837,148 - 73,881,820 (+)NCBIT2T-CHM13v2.0
Stambp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,520,188 - 83,552,781 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl683,520,193 - 83,549,711 (-)EnsemblGRCm39 Ensembl
GRCm38683,543,206 - 83,575,826 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,543,211 - 83,572,729 (-)EnsemblGRCm38mm10GRCm38
MGSCv37683,493,200 - 83,522,498 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36683,508,864 - 83,538,093 (-)NCBIMGSCv36mm8
Celera685,524,336 - 85,552,555 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
Stambp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,831,361 - 11,879,577 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,831,910 - 11,879,577 (-)NCBIChiLan1.0ChiLan1.0
STAMBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21252,521,347 - 52,557,736 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A52,524,101 - 52,570,824 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A73,900,128 - 73,936,571 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A75,410,352 - 75,451,082 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A75,410,434 - 75,451,086 (+)Ensemblpanpan1.1panPan2
STAMBP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11749,194,810 - 49,221,017 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1749,195,101 - 49,221,013 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,838,657 - 48,864,889 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01750,056,958 - 50,083,265 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1750,056,958 - 50,083,190 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11749,073,147 - 49,099,470 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01749,140,501 - 49,166,821 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01749,699,497 - 49,725,831 (-)NCBIUU_Cfam_GSD_1.0
Stambp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629210,563,513 - 10,594,463 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936556143,483 - 174,383 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAMBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,133,978 - 69,188,192 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,156,012 - 69,188,256 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2372,359,731 - 72,389,751 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STAMBP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11433,417,342 - 33,453,507 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1433,416,821 - 33,451,593 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604578,714,497 - 78,750,436 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stambp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474929,630,847 - 29,667,571 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474929,630,847 - 29,667,611 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Stambp
81 total Variants

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:36
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000014708
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106649412151649412Rat

1 to 10 of 51 rows
AW107289  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24116,055,715 - 116,055,833 (+)MAPPERmRatBN7.2
Rnor_6.04115,249,005 - 115,249,122NCBIRnor6.0
Rnor_5.04179,839,513 - 179,839,630UniSTSRnor5.0
RGSC_v3.44117,766,567 - 117,766,684UniSTSRGSC3.4
Celera4105,048,971 - 105,049,088UniSTS
Cytogenetic Map4q34UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000014708   ⟹   ENSRNOP00000014708
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4116,056,057 - 116,080,543 (-)Ensembl
Rnor_6.0 Ensembl4115,249,351 - 115,273,836 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086968   ⟹   ENSRNOP00000069824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4115,249,352 - 115,275,068 (-)Ensembl
RefSeq Acc Id: NM_138531   ⟹   NP_612540
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,613,730 - 117,638,220 (-)NCBI
mRatBN7.24116,056,054 - 116,080,548 (-)NCBI
Rnor_6.04115,249,343 - 115,273,836 (-)NCBI
Rnor_5.04179,839,851 - 179,867,468 (-)NCBI
RGSC_v3.44117,766,905 - 117,791,399 (-)RGD
Celera4105,049,309 - 105,073,789 (-)RGD
Sequence:
RefSeq Acc Id: XM_006236726   ⟹   XP_006236788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,613,730 - 117,642,163 (-)NCBI
mRatBN7.24116,055,563 - 116,083,563 (-)NCBI
Rnor_6.04115,249,346 - 115,277,340 (-)NCBI
Rnor_5.04179,839,851 - 179,867,468 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006236727   ⟹   XP_006236789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,613,730 - 117,642,163 (-)NCBI
mRatBN7.24116,055,563 - 116,083,563 (-)NCBI
Rnor_6.04115,249,346 - 115,277,340 (-)NCBI
Rnor_5.04179,839,851 - 179,867,468 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039106986   ⟹   XP_038962914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,613,730 - 117,642,163 (-)NCBI
mRatBN7.24116,055,563 - 116,083,563 (-)NCBI
RefSeq Acc Id: XM_039106987   ⟹   XP_038962915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,613,730 - 117,642,163 (-)NCBI
mRatBN7.24116,055,563 - 116,080,468 (-)NCBI
RefSeq Acc Id: XM_063285460   ⟹   XP_063141530
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,613,730 - 117,641,244 (-)NCBI
RefSeq Acc Id: NP_612540   ⟸   NM_138531
- UniProtKB: Q8R424 (UniProtKB/Swiss-Prot),   A6IAN4 (UniProtKB/TrEMBL),   A6IAN6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236788   ⟸   XM_006236726
- Peptide Label: isoform X1
- UniProtKB: Q8R424 (UniProtKB/Swiss-Prot),   A6IAN4 (UniProtKB/TrEMBL),   A6IAN6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236789   ⟸   XM_006236727
- Peptide Label: isoform X1
- UniProtKB: Q8R424 (UniProtKB/Swiss-Prot),   A6IAN4 (UniProtKB/TrEMBL),   A6IAN6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014708   ⟸   ENSRNOT00000014708
Ensembl Acc Id: ENSRNOP00000069824   ⟸   ENSRNOT00000086968
MPN

Name Modeler Protein Id AA Range Protein Structure
AF-Q8R424-F1-model_v2 AlphaFold Q8R424 1-424 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693182
Promoter ID:EPDNEW_R3706
Type:multiple initiation site
Name:Stambp_1
Description:Stam binding protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04115,273,843 - 115,273,903EPDNEW


1 to 28 of 28 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-44002 BioCyc
Ensembl Genes ENSRNOG00000012227 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014708 ENTREZGENE
  ENSRNOT00000014708.6 UniProtKB/Swiss-Prot
Gene3D-CATH Cytidine Deaminase, domain 2 UniProtKB/Swiss-Prot
  Phosphotransferase system, lactose/cellobiose-type IIA subunit UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5597943 IMAGE-MGC_LOAD
InterPro JAMM/MPN+_dom UniProtKB/Swiss-Prot
  MPN UniProtKB/Swiss-Prot
  STAMBP/STALP-like_MPN UniProtKB/Swiss-Prot
  USP8_dimer UniProtKB/Swiss-Prot
KEGG Report rno:171565 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72308 IMAGE-MGC_LOAD
NCBI Gene 171565 ENTREZGENE
PANTHER AMSH-LIKE PROTEASE UniProtKB/Swiss-Prot
  STAM-BINDING PROTEIN UniProtKB/Swiss-Prot
Pfam JAB UniProtKB/Swiss-Prot
  USP8_dimer UniProtKB/Swiss-Prot
PhenoGen Stambp PhenoGen
PROSITE MPN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012227 RatGTEx
SMART JAB_MPN UniProtKB/Swiss-Prot
Superfamily-SCOP JAB1/MPN domain UniProtKB/Swiss-Prot
  USP8 N-terminal domain-like UniProtKB/Swiss-Prot
UniProt A6IAN3_RAT UniProtKB/TrEMBL
  A6IAN4 ENTREZGENE, UniProtKB/TrEMBL
  A6IAN6 ENTREZGENE, UniProtKB/TrEMBL
  Q8R424 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 28 of 28 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Stambp  Stam binding protein    associated molecule with the SH3 domain of STAM  Name updated 1299863 APPROVED
2004-09-10 Stambp  associated molecule with the SH3 domain of STAM  Amsh    Symbol and Name updated 1299863 APPROVED
2002-08-07 Amsh  associated molecule with the SH3 domain of STAM      Symbol and Name status set to provisional 70820 PROVISIONAL