Ugt8 (UDP glycosyltransferase 8) - Rat Genome Database

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Gene: Ugt8 (UDP glycosyltransferase 8) Rattus norvegicus
Analyze
Symbol: Ugt8
Name: UDP glycosyltransferase 8
RGD ID: 3938
Description: Enables 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity and UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity. Involved in galactosylceramide biosynthetic process and response to immobilization stress. Located in endoplasmic reticulum. Orthologous to human UGT8 (UDP glycosyltransferase 8); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; ceramide UDP-galactosyltransferase; cerebroside synthase; CGalT; UDP galactosyltransferase 8; UDP galactosyltransferase 8A; UDP-galactose-ceramide galactosyltransferase 8; UDP-glucuronosyltransferase 8; Ugt8a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82216,938,884 - 217,007,167 (-)NCBIGRCr8
mRatBN7.22214,264,483 - 214,332,769 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2214,264,483 - 214,332,660 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2221,935,494 - 222,003,681 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02219,835,423 - 219,903,608 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02214,689,623 - 214,757,812 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02229,644,373 - 229,718,678 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2229,644,382 - 229,718,659 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02248,998,871 - 249,072,741 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42222,977,966 - 223,048,277 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1436,844,752 - 36,845,448 (+)NCBI
Celera2206,609,425 - 206,656,289 (-)NCBICelera
Cytogenetic Map2q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability. Coetzee T, etal., Cell 1996 Jul 26;86(2):209-19.
2. Myelin galactolipids are essential for proper node of Ranvier formation in the CNS. Dupree JL, etal., J Neurosci 1998 Mar 1;18(5):1642-9.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expression. Schulte S and Stoffel W, Proc Natl Acad Sci U S A 1993 Nov 1;90(21):10265-9.
13. Isolation, characterization, and expression of cDNA clones that encode rat UDP-galactose: ceramide galactosyltransferase. Stahl N, etal., J Neurosci Res 1994 Jun 1;38(2):234-42.
14. Enriched Environment Enhances the Myelin Regulatory Factor by mTOR Signaling and Protects the Myelin Membrane Against Oxidative Damage in Rats Exposed to Chronic Immobilization Stress. Thamizhoviya G and Vanisree AJ, Neurochem Res. 2021 Dec;46(12):3314-3324. doi: 10.1007/s11064-021-03433-8. Epub 2021 Aug 27.
15. Synthesis of non-hydroxy-galactosylceramides and galactosyldiglycerides by hydroxy-ceramide galactosyltransferase. van der Bijl P, etal., Biochem J. 1996 Jul 15;317 ( Pt 2):589-97. doi: 10.1042/bj3170589.
Additional References at PubMed
PMID:8889548   PMID:12060780   PMID:16551741  


Genomics

Comparative Map Data
Ugt8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82216,938,884 - 217,007,167 (-)NCBIGRCr8
mRatBN7.22214,264,483 - 214,332,769 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2214,264,483 - 214,332,660 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2221,935,494 - 222,003,681 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02219,835,423 - 219,903,608 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02214,689,623 - 214,757,812 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02229,644,373 - 229,718,678 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2229,644,382 - 229,718,659 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02248,998,871 - 249,072,741 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42222,977,966 - 223,048,277 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1436,844,752 - 36,845,448 (+)NCBI
Celera2206,609,425 - 206,656,289 (-)NCBICelera
Cytogenetic Map2q42NCBI
UGT8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384114,598,402 - 114,678,225 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4114,598,770 - 114,678,225 (+)EnsemblGRCh38hg38GRCh38
GRCh374115,519,558 - 115,599,381 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364115,762,972 - 115,817,201 (+)NCBINCBI36Build 36hg18NCBI36
Build 344115,901,126 - 115,955,356NCBI
Celera4112,813,079 - 112,891,640 (+)NCBICelera
Cytogenetic Map4q26NCBI
HuRef4111,253,852 - 111,332,365 (+)NCBIHuRef
CHM1_14115,496,077 - 115,574,635 (+)NCBICHM1_1
T2T-CHM13v2.04117,901,444 - 117,981,528 (+)NCBIT2T-CHM13v2.0
Ugt8a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393125,655,071 - 125,732,301 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3125,658,920 - 125,732,268 (-)EnsemblGRCm39 Ensembl
GRCm383125,865,272 - 125,938,682 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3125,865,271 - 125,938,619 (-)EnsemblGRCm38mm10GRCm38
MGSCv373125,568,261 - 125,641,468 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363125,857,534 - 125,907,483 (-)NCBIMGSCv36mm8
Celera3132,313,587 - 132,366,589 (-)NCBICelera
Cytogenetic Map3G1NCBI
cM Map354.68NCBI
Ugt8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542824,800,854 - 24,865,378 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542824,800,854 - 24,864,904 (-)NCBIChiLan1.0ChiLan1.0
UGT8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23112,702,522 - 112,788,302 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14112,993,894 - 113,079,701 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04107,113,476 - 107,199,272 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14117,676,804 - 117,762,363 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4117,676,810 - 117,762,729 (+)Ensemblpanpan1.1panPan2
UGT8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13234,148,874 - 34,250,891 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3234,179,247 - 34,233,116 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha327,771,814 - 7,877,424 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03234,375,940 - 34,480,809 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3234,194,392 - 34,547,378 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13234,352,188 - 34,479,955 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03234,121,751 - 34,227,483 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0325,634,135 - 5,739,686 (-)NCBIUU_Cfam_GSD_1.0
Ugt8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053016,603,659 - 6,685,574 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365635,224,173 - 5,306,120 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365635,251,451 - 5,305,683 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UGT8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8108,233,143 - 108,314,921 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18108,233,134 - 108,315,284 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28115,965,708 - 115,974,792 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UGT8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1762,380,506 - 62,465,695 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl762,381,223 - 62,466,401 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603741,154,173 - 41,238,937 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ugt8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248671,182,589 - 1,255,796 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248671,182,674 - 1,255,714 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ugt8
509 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:520
Count of miRNA genes:275
Interacting mature miRNAs:338
Transcripts:ENSRNOT00000012676
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1298083Bp158Blood pressure QTL 1582.62arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1331745Bp203Blood pressure QTL 2034.377arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2189599258218414891Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2185876309219753474Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2185876309219753474Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
631203Gluco14Glucose level QTL 140.0001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)2206665645219003804Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
2299161Iddm33Insulin dependent diabetes mellitus QTL 332.98blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2206312063220876787Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat

Markers in Region
X92122  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22214,266,036 - 214,266,184 (+)MAPPERmRatBN7.2
Rnor_6.02229,646,033 - 229,646,180NCBIRnor6.0
Rnor_5.02249,000,425 - 249,000,572UniSTSRnor5.0
RGSC_v3.42222,979,520 - 222,979,667UniSTSRGSC3.4
Celera2206,610,979 - 206,611,126UniSTS
Cytogenetic Map2q42UniSTS
RH136801  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22214,264,648 - 214,264,768 (+)MAPPERmRatBN7.2
Rnor_6.02229,644,645 - 229,644,764NCBIRnor6.0
Rnor_5.02248,999,037 - 248,999,156UniSTSRnor5.0
RGSC_v3.42222,978,132 - 222,978,251UniSTSRGSC3.4
Celera2206,609,591 - 206,609,710UniSTS
RH 3.4 Map21546.6UniSTS
Cytogenetic Map2q42UniSTS
Ugt8a  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22214,266,341 - 214,266,603 (+)MAPPERmRatBN7.2
Rnor_6.02229,646,338 - 229,646,599NCBIRnor6.0
Rnor_5.02249,000,730 - 249,000,991UniSTSRnor5.0
RGSC_v3.42222,979,825 - 222,980,086UniSTSRGSC3.4
Celera2206,611,284 - 206,611,545UniSTS
Cytogenetic Map2q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 2 2 33 14 4 2
Low 2 16 16 12 5 12 5 5 41 21 36 10 5
Below cutoff 24 29 17 13 17 1 4 1 1 1

Sequence


RefSeq Acc Id: ENSRNOT00000012676   ⟹   ENSRNOP00000012676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2214,264,483 - 214,332,660 (-)Ensembl
Rnor_6.0 Ensembl2229,644,382 - 229,718,659 (-)Ensembl
RefSeq Acc Id: NM_019276   ⟹   NP_062149
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82216,938,990 - 217,007,167 (-)NCBI
mRatBN7.22214,264,483 - 214,332,660 (-)NCBI
Rnor_6.02229,644,479 - 229,718,672 (-)NCBI
Rnor_5.02248,998,871 - 249,072,741 (-)NCBI
RGSC_v3.42222,977,966 - 223,048,277 (-)RGD
Celera2206,609,425 - 206,656,289 (-)RGD
Sequence:
RefSeq Acc Id: XM_017591052   ⟹   XP_017446541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82216,938,884 - 217,007,155 (-)NCBI
mRatBN7.22214,266,268 - 214,332,769 (-)NCBI
Rnor_6.02229,644,373 - 229,718,678 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063282414   ⟹   XP_063138484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82216,938,884 - 217,004,826 (-)NCBI
RefSeq Acc Id: NP_062149   ⟸   NM_019276
- Peptide Label: precursor
- UniProtKB: Q09426 (UniProtKB/Swiss-Prot),   A6HVK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446541   ⟸   XM_017591052
- Peptide Label: isoform X1
- UniProtKB: Q09426 (UniProtKB/Swiss-Prot),   A6HVK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012676   ⟸   ENSRNOT00000012676
RefSeq Acc Id: XP_063138484   ⟸   XM_063282414
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q09426-F1-model_v2 AlphaFold Q09426 1-541 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691736
Promoter ID:EPDNEW_R2261
Type:single initiation site
Name:Ugt8_1
Description:UDP glycosyltransferase 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02229,718,746 - 229,718,806EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3938 AgrOrtholog
BioCyc Gene G2FUF-51291 BioCyc
BioCyc Pathway PWY-7840 [gala-series glycosphingolipids biosynthesis] BioCyc
BioCyc Pathway Image PWY-7840 BioCyc
Ensembl Genes ENSRNOG00000009345 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055025244 UniProtKB/Swiss-Prot
  ENSRNOG00060002891 UniProtKB/Swiss-Prot
  ENSRNOG00065014436 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012676 ENTREZGENE
  ENSRNOT00000012676.5 UniProtKB/Swiss-Prot
  ENSRNOT00055043511 UniProtKB/Swiss-Prot
  ENSRNOT00060004674 UniProtKB/Swiss-Prot
  ENSRNOT00065023839 UniProtKB/Swiss-Prot
Gene3D-CATH Glycogen Phosphorylase B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro UDP_glucos_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP_glycos_trans_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:50555 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 50555 ENTREZGENE
PANTHER 2-HYDROXYACYLSPHINGOSINE 1-BETA-GALACTOSYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EG:EG0003.4 PROTEIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam UDPGT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ugt8 PhenoGen
PROSITE UDPGT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009345 RatGTEx
  ENSRNOG00055025244 RatGTEx
  ENSRNOG00060002891 RatGTEx
  ENSRNOG00065014436 RatGTEx
Superfamily-SCOP UDP-Glycosyltransferase/glycogen phosphorylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6HVK3 ENTREZGENE, UniProtKB/TrEMBL
  A6HVK4_RAT UniProtKB/TrEMBL
  CGT_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-08-29 Ugt8  UDP glycosyltransferase 8  Ugt8a  UDP galactosyltransferase 8A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Ugt8a  UDP galactosyltransferase 8A  Ugt8  UDP galactosyltransferase 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Ugt8  UDP galactosyltransferase 8      Name updated 1299863 APPROVED
2002-06-10 Ugt8  UDP-glucuronosyltransferase 8       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression developmental expression of mRNA similar to the myelination profile 70050
gene_protein predicted protein masses 61 kDa 70050
gene_transcript open reading frame of 1623 bp 70050