Ugt8 (UDP glycosyltransferase 8) - Rat Genome Database

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Gene: Ugt8 (UDP glycosyltransferase 8) Rattus norvegicus
Analyze
Symbol: Ugt8
Name: UDP glycosyltransferase 8
RGD ID: 3938
Description: Enables N-acylsphingosine galactosyltransferase activity and UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity. Involved in galactosylceramide biosynthetic process and response to immobilization stress. Located in endoplasmic reticulum. Orthologous to human UGT8 (UDP glycosyltransferase 8); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; ceramide UDP-galactosyltransferase; cerebroside synthase; CGalT; UDP galactosyltransferase 8; UDP galactosyltransferase 8A; UDP-galactose-ceramide galactosyltransferase 8; UDP-glucuronosyltransferase 8; Ugt8a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82216,938,884 - 217,007,167 (-)NCBIGRCr8
mRatBN7.22214,264,483 - 214,332,769 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2214,264,483 - 214,332,660 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2221,935,494 - 222,003,681 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02219,835,423 - 219,903,608 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02214,689,623 - 214,757,812 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02229,644,373 - 229,718,678 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2229,644,382 - 229,718,659 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02248,998,871 - 249,072,741 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42222,977,966 - 223,048,277 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1436,844,752 - 36,845,448 (+)NCBI
Celera2206,609,425 - 206,656,289 (-)NCBICelera
Cytogenetic Map2q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 85 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugt8Rat1,2-dimethylhydrazine decreases expressionISOUgt8a (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of UGT8A mRNACTDPMID:22206623
Ugt8Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOUgt8a (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of UGT8A mRNACTDPMID:33956508
Ugt8Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of UGT8 mRNACTDPMID:33387578
Ugt8Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Ugt8Rat4,4'-diaminodiphenylmethane increases expressionISOUgt8a (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in increased expression of UGT8 mRNACTDPMID:18648102
Ugt8Rat5-fluorouracil multiple interactionsISOUGT8 (Homo sapiens)6480464TP53 protein affects the reaction [Fluorouracil results in decreased expression of UGT8 mRNA]CTDPMID:15016801
Ugt8Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of UGT8 mRNACTDPMID:24780913 and PMID:25825206
Ugt8Rataflatoxin B1 affects expressionISOUGT8 (Homo sapiens)6480464Aflatoxin B1 affects the expression of UGT8 proteinCTDPMID:20106945
Ugt8Ratall-trans-retinoic acid increases expressionISOUGT8 (Homo sapiens)6480464Tretinoin results in increased expression of UGT8 mRNACTDPMID:21934132
Ugt8Ratall-trans-retinoic acid increases expressionISOUgt8a (Mus musculus)6480464Tretinoin results in increased expression of UGT8A mRNACTDPMID:36189433
Ugt8Ratall-trans-retinoic acid multiple interactionsISOUgt8a (Mus musculus)6480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of UGT8A mRNACTDPMID:36189433
Ugt8Ratalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of UGT8 mRNA and [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of UGT8 mRNACTDPMID:35163327
Ugt8Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of UGT8 mRNACTDPMID:38685447
Ugt8Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of UGT8 mRNACTDPMID:16483693
Ugt8Rataristolochic acid A decreases expressionISOUGT8 (Homo sapiens)6480464aristolochic acid I results in decreased expression of UGT8 mRNACTDPMID:33212167
Ugt8Ratarsenite(3-) decreases expressionISOUGT8 (Homo sapiens)6480464arsenite results in decreased expression of UGT8 mRNACTDPMID:23974009
Ugt8Ratbelinostat increases expressionISOUGT8 (Homo sapiens)6480464belinostat results in increased expression of UGT8 mRNACTDPMID:26272509
Ugt8Ratbelinostat multiple interactionsISOUGT8 (Homo sapiens)6480464[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of UGT8 mRNACTDPMID:27188386
Ugt8Ratbenzo[a]pyrene decreases expressionISOUgt8a (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of UGT8A mRNACTDPMID:22228805
Ugt8Ratbenzo[a]pyrene increases methylationISOUGT8 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of UGT8 5' UTR and Benzo(a)pyrene results in increased methylation of UGT8 promoterCTDPMID:27901495

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Biological Process
1 to 16 of 16 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugt8Ratcytoskeleton organization involved_inIEAUniProtKB:Q64676 and ensembl:ENSMUSP000001436051600115GO_REF:0000107EnsemblGO_REF:0000107
Ugt8Ratcytoskeleton organization involved_inISOUgt8a (Mus musculus)1624291 PMID:16551741RGDPMID:16551741
Ugt8Ratgalactosylceramide biosynthetic process involved_inIDA 39458006PMID:8713090UniProt 
Ugt8Ratgalactosylceramide biosynthetic process involved_inIBAPANTHER:PTN002630013 and Ugt8 (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ugt8Ratgalactosylceramide biosynthetic process involved_inIEAUniPathway:UPA007871600115GO_REF:0000041UniProtGO_REF:0000041
Ugt8Ratglycosphingolipid biosynthetic process  TAS 70050 RGD 
Ugt8Ratlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Ugt8Ratmyelination  TAS 70050 RGD 
Ugt8Ratneuron projection morphogenesis involved_inISOUgt8a (Mus musculus)1624291 PMID:16551741RGDPMID:16551741
Ugt8Ratneuron projection morphogenesis involved_inIEAUniProtKB:Q64676 and ensembl:ENSMUSP000001436051600115GO_REF:0000107EnsemblGO_REF:0000107
Ugt8Ratparanodal junction assembly involved_inISOUgt8a (Mus musculus)1624291 PMID:16551741RGDPMID:16551741
Ugt8Ratparanodal junction assembly involved_inIEAUniProtKB:Q64676 and ensembl:ENSMUSP000001436051600115GO_REF:0000107EnsemblGO_REF:0000107
Ugt8Ratprotein localization to paranode region of axon involved_inISOUgt8a (Mus musculus)1624291 PMID:16551741RGDPMID:16551741
Ugt8Ratprotein localization to paranode region of axon involved_inIEAUniProtKB:Q64676 and ensembl:ENSMUSP000001436051600115GO_REF:0000107EnsemblGO_REF:0000107
Ugt8Ratresponse to immobilization stress  IEP 213230152 RGD 
Ugt8Ratsphingolipid metabolic process involved_inIEAUniProtKB-KW:KW-07461600115GO_REF:0000043UniProtGO_REF:0000043
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Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugt8Ratendoplasmic reticulum located_inIDA 39458006PMID:8713090UniProt 
Ugt8Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Ugt8Ratendoplasmic reticulum located_inIEAUniProtKB-SubCell:SL-00951600115GO_REF:0000044UniProtGO_REF:0000044
Ugt8Ratendoplasmic reticulum is_active_inIBAPANTHER:PTN002630013 and Ugt8 (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ugt8Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Ugt8Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugt8Ratglycosyltransferase activity enablesIEAUniProtKB-KW:KW-03281600115GO_REF:0000043UniProtGO_REF:0000043
Ugt8RatN-acylsphingosine galactosyltransferase activity enablesIDA 39458006PMID:8713090UniProt 
Ugt8RatN-acylsphingosine galactosyltransferase activity enablesIEAEC:2.4.1.471600115GO_REF:0000003UniProtGO_REF:0000003
Ugt8RatN-acylsphingosine galactosyltransferase activity enablesIBAPANTHER:PTN002630013 and Ugt8 (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ugt8RatN-acylsphingosine galactosyltransferase activity enablesIEARHEA:130931600115GO_REF:0000116RHEAGO_REF:0000116
Ugt8Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
Ugt8RatUDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity  IMP 70050 RGD 
Ugt8RatUDP-glycosyltransferase activity enablesIEAInterPro:IPR0022131600115GO_REF:0000002InterProGO_REF:0000002

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ugt8Ratsphingolipid metabolic pathway  IEA 6907045 KEGGrno:00600

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#
Reference Title
Reference Citation
1. Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability. Coetzee T, etal., Cell 1996 Jul 26;86(2):209-19.
2. Myelin galactolipids are essential for proper node of Ranvier formation in the CNS. Dupree JL, etal., J Neurosci 1998 Mar 1;18(5):1642-9.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expression. Schulte S and Stoffel W, Proc Natl Acad Sci U S A 1993 Nov 1;90(21):10265-9.
13. Isolation, characterization, and expression of cDNA clones that encode rat UDP-galactose: ceramide galactosyltransferase. Stahl N, etal., J Neurosci Res 1994 Jun 1;38(2):234-42.
14. Enriched Environment Enhances the Myelin Regulatory Factor by mTOR Signaling and Protects the Myelin Membrane Against Oxidative Damage in Rats Exposed to Chronic Immobilization Stress. Thamizhoviya G and Vanisree AJ, Neurochem Res. 2021 Dec;46(12):3314-3324. doi: 10.1007/s11064-021-03433-8. Epub 2021 Aug 27.
15. Synthesis of non-hydroxy-galactosylceramides and galactosyldiglycerides by hydroxy-ceramide galactosyltransferase. van der Bijl P, etal., Biochem J. 1996 Jul 15;317 ( Pt 2):589-97. doi: 10.1042/bj3170589.
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PMID:8889548   PMID:12060780   PMID:16551741  



Ugt8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82216,938,884 - 217,007,167 (-)NCBIGRCr8
mRatBN7.22214,264,483 - 214,332,769 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2214,264,483 - 214,332,660 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2221,935,494 - 222,003,681 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02219,835,423 - 219,903,608 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02214,689,623 - 214,757,812 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02229,644,373 - 229,718,678 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2229,644,382 - 229,718,659 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02248,998,871 - 249,072,741 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42222,977,966 - 223,048,277 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1436,844,752 - 36,845,448 (+)NCBI
Celera2206,609,425 - 206,656,289 (-)NCBICelera
Cytogenetic Map2q42NCBI
UGT8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384114,598,402 - 114,678,225 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4114,598,770 - 114,678,588 (+)EnsemblGRCh38hg38GRCh38
GRCh374115,519,558 - 115,599,381 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364115,762,972 - 115,817,201 (+)NCBINCBI36Build 36hg18NCBI36
Build 344115,901,126 - 115,955,356NCBI
Celera4112,813,079 - 112,891,640 (+)NCBICelera
Cytogenetic Map4q26NCBI
HuRef4111,253,852 - 111,332,365 (+)NCBIHuRef
CHM1_14115,496,077 - 115,574,635 (+)NCBICHM1_1
T2T-CHM13v2.04117,901,444 - 117,981,528 (+)NCBIT2T-CHM13v2.0
Ugt8a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393125,655,071 - 125,732,301 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3125,658,920 - 125,732,268 (-)EnsemblGRCm39 Ensembl
GRCm383125,865,272 - 125,938,682 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3125,865,271 - 125,938,619 (-)EnsemblGRCm38mm10GRCm38
MGSCv373125,568,261 - 125,641,468 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363125,857,534 - 125,907,483 (-)NCBIMGSCv36mm8
Celera3132,313,587 - 132,366,589 (-)NCBICelera
Cytogenetic Map3G1NCBI
cM Map354.68NCBI
Ugt8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542824,800,854 - 24,865,378 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542824,800,854 - 24,864,904 (-)NCBIChiLan1.0ChiLan1.0
UGT8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23112,702,522 - 112,788,302 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14112,993,894 - 113,079,701 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04107,113,476 - 107,199,272 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14117,676,804 - 117,762,363 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4117,676,810 - 117,762,729 (+)Ensemblpanpan1.1panPan2
UGT8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13234,148,874 - 34,250,891 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3234,179,247 - 34,233,116 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha327,771,814 - 7,877,424 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03234,375,940 - 34,480,809 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3234,194,392 - 34,547,378 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13234,352,188 - 34,479,955 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03234,121,751 - 34,227,483 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0325,634,135 - 5,739,686 (-)NCBIUU_Cfam_GSD_1.0
Ugt8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053016,603,659 - 6,685,574 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365635,224,173 - 5,306,120 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365635,251,451 - 5,305,683 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UGT8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8108,233,143 - 108,314,921 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18108,233,134 - 108,315,284 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28115,965,708 - 115,974,792 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UGT8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1762,380,506 - 62,465,695 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl762,381,223 - 62,466,401 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603741,154,173 - 41,238,937 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ugt8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248671,182,589 - 1,255,796 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248671,182,674 - 1,255,714 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ugt8
541 total Variants

Predicted Target Of
Summary Value
Count of predictions:520
Count of miRNA genes:275
Interacting mature miRNAs:338
Transcripts:ENSRNOT00000012676
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat

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X92122  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22214,266,036 - 214,266,184 (+)MAPPERmRatBN7.2
Rnor_6.02229,646,033 - 229,646,180NCBIRnor6.0
Rnor_5.02249,000,425 - 249,000,572UniSTSRnor5.0
RGSC_v3.42222,979,520 - 222,979,667UniSTSRGSC3.4
Celera2206,610,979 - 206,611,126UniSTS
Cytogenetic Map2q42UniSTS
RH136801  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22214,264,648 - 214,264,768 (+)MAPPERmRatBN7.2
Rnor_6.02229,644,645 - 229,644,764NCBIRnor6.0
Rnor_5.02248,999,037 - 248,999,156UniSTSRnor5.0
RGSC_v3.42222,978,132 - 222,978,251UniSTSRGSC3.4
Celera2206,609,591 - 206,609,710UniSTS
RH 3.4 Map21546.6UniSTS
Cytogenetic Map2q42UniSTS
Ugt8a  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22214,266,341 - 214,266,603 (+)MAPPERmRatBN7.2
Rnor_6.02229,646,338 - 229,646,599NCBIRnor6.0
Rnor_5.02249,000,730 - 249,000,991UniSTSRnor5.0
RGSC_v3.42222,979,825 - 222,980,086UniSTSRGSC3.4
Celera2206,611,284 - 206,611,545UniSTS
Cytogenetic Map2q42UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 46 113 72 71 40 24 40 6 195 93 93 45 60 31



Ensembl Acc Id: ENSRNOT00000012676   ⟹   ENSRNOP00000012676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2214,264,483 - 214,332,660 (-)Ensembl
Rnor_6.0 Ensembl2229,644,382 - 229,718,659 (-)Ensembl
RefSeq Acc Id: NM_019276   ⟹   NP_062149
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82216,938,990 - 217,007,167 (-)NCBI
mRatBN7.22214,264,483 - 214,332,660 (-)NCBI
Rnor_6.02229,644,479 - 229,718,672 (-)NCBI
Rnor_5.02248,998,871 - 249,072,741 (-)NCBI
RGSC_v3.42222,977,966 - 223,048,277 (-)RGD
Celera2206,609,425 - 206,656,289 (-)RGD
Sequence:
RefSeq Acc Id: XM_017591052   ⟹   XP_017446541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82216,938,884 - 217,007,155 (-)NCBI
mRatBN7.22214,266,268 - 214,332,769 (-)NCBI
Rnor_6.02229,644,373 - 229,718,678 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063282414   ⟹   XP_063138484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82216,938,884 - 217,004,826 (-)NCBI
1 to 9 of 9 rows
Protein RefSeqs NP_062149 (Get FASTA)   NCBI Sequence Viewer  
  XP_017446541 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138484 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA16108 (Get FASTA)   NCBI Sequence Viewer  
  EDL82139 (Get FASTA)   NCBI Sequence Viewer  
  EDL82140 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012676
  ENSRNOP00000012676.2
GenBank Protein Q09426 (Get FASTA)   NCBI Sequence Viewer  
1 to 9 of 9 rows
RefSeq Acc Id: NP_062149   ⟸   NM_019276
- Peptide Label: precursor
- UniProtKB: Q09426 (UniProtKB/Swiss-Prot),   A6HVK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446541   ⟸   XM_017591052
- Peptide Label: isoform X1
- UniProtKB: Q09426 (UniProtKB/Swiss-Prot),   A6HVK3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012676   ⟸   ENSRNOT00000012676
RefSeq Acc Id: XP_063138484   ⟸   XM_063282414
- Peptide Label: isoform X1
- UniProtKB: Q09426 (UniProtKB/Swiss-Prot),   A6HVK3 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-Q09426-F1-model_v2 AlphaFold Q09426 1-541 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691736
Promoter ID:EPDNEW_R2261
Type:single initiation site
Name:Ugt8_1
Description:UDP glycosyltransferase 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02229,718,746 - 229,718,806EPDNEW


1 to 22 of 22 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-51291 BioCyc
BioCyc Pathway PWY-7840 [gala-series glycosphingolipids biosynthesis] BioCyc
BioCyc Pathway Image PWY-7840 BioCyc
Ensembl Genes ENSRNOG00000009345 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012676 ENTREZGENE
  ENSRNOT00000012676.5 UniProtKB/Swiss-Prot
Gene3D-CATH Glycogen Phosphorylase B UniProtKB/Swiss-Prot
InterPro UDP-glycosyltransferase UniProtKB/Swiss-Prot
  UDP_glucos_trans UniProtKB/Swiss-Prot
  UDP_glycos_trans_CS UniProtKB/Swiss-Prot
KEGG Report rno:50555 UniProtKB/Swiss-Prot
NCBI Gene 50555 ENTREZGENE
PANTHER 2-HYDROXYACYLSPHINGOSINE 1-BETA-GALACTOSYLTRANSFERASE UniProtKB/Swiss-Prot
  EG:EG0003.4 PROTEIN-RELATED UniProtKB/Swiss-Prot
Pfam UDPGT UniProtKB/Swiss-Prot
PhenoGen Ugt8 PhenoGen
PROSITE UDPGT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009345 RatGTEx
Superfamily-SCOP UDP-Glycosyltransferase/glycogen phosphorylase UniProtKB/Swiss-Prot
UniProt A6HVK3 ENTREZGENE, UniProtKB/TrEMBL
  A6HVK4_RAT UniProtKB/TrEMBL
  CGT_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 22 of 22 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-08-29 Ugt8  UDP glycosyltransferase 8  Ugt8a  UDP galactosyltransferase 8A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Ugt8a  UDP galactosyltransferase 8A  Ugt8  UDP galactosyltransferase 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Ugt8  UDP galactosyltransferase 8      Name updated 1299863 APPROVED
2002-06-10 Ugt8  UDP-glucuronosyltransferase 8       Name updated 70584 APPROVED

Note Type Note Reference
gene_expression developmental expression of mRNA similar to the myelination profile 70050
gene_protein predicted protein masses 61 kDa 70050
gene_transcript open reading frame of 1623 bp 70050