Tp53 | Rat | (+)-(S)-ar-turmerone | increases expression | ISO | RGD:70502 | 6480464 | ar-turmerone results in increased expression of TP53 mRNA; ar-turmerone results in increased expression of TP53 more ... | CTD | PMID:19250610 |
Tp53 | Rat | (+)-artemisinin | increases activity | ISO | RGD:70502 | 6480464 | artemisinin results in increased activity of TP53 protein | CTD | PMID:30818834 |
Tp53 | Rat | (+)-catechin | multiple interactions | ISO | RGD:11440 | 6480464 | Catechin inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of TRP53 protein] | CTD | PMID:15879681 |
Tp53 | Rat | (+)-catechin | multiple interactions | EXP | | 6480464 | Catechin inhibits the reaction [Rotenone results in increased expression of TP53 mRNA] | CTD | PMID:35337893 |
Tp53 | Rat | (+)-catechin | increases expression | ISO | RGD:70502 | 6480464 | Catechin results in increased expression of TP53 mRNA; Catechin results in increased expression of TP53 more ... | CTD | PMID:23706674 |
Tp53 | Rat | (+)-dexrazoxane | multiple interactions | ISO | RGD:11440 | 6480464 | Dexrazoxane inhibits the reaction [Idarubicin results in increased expression of TRP53 mRNA] | CTD | PMID:28973540 |
Tp53 | Rat | (+)-dexrazoxane | multiple interactions | EXP | | 6480464 | Dexrazoxane inhibits the reaction [Daunorubicin results in increased phosphorylation of TP53 protein] | CTD | PMID:38290791 |
Tp53 | Rat | (+)-epicatechin-3-O-gallate | multiple interactions | ISO | RGD:11440 | 6480464 | epicatechin gallate promotes the reaction [Benzo(a)pyrene results in increased expression of TRP53 mRNA] | CTD | PMID:18656336 |
Tp53 | Rat | (+)-schisandrin B | multiple interactions | ISO | RGD:11440 | 6480464 | [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in more ... | CTD | PMID:22003191 |
Tp53 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TP53 mRNA] | CTD | PMID:31150632 |
Tp53 | Rat | (-)-alpha-phellandrene | decreases expression | ISO | RGD:11440 | 6480464 | alpha phellandrene results in decreased expression of TRP53 protein | CTD | PMID:24861204 |
Tp53 | Rat | (-)-alpha-phellandrene | increases expression | ISO | RGD:11440 | 6480464 | alpha phellandrene results in increased expression of TRP53 protein modified form | CTD | PMID:24861204 |
Tp53 | Rat | (-)-alpha-phellandrene | increases phosphorylation | ISO | RGD:11440 | 6480464 | alpha phellandrene results in increased phosphorylation of TRP53 protein | CTD | PMID:24861204 |
Tp53 | Rat | (-)-alpha-phellandrene | affects localization | ISO | RGD:70502 | 6480464 | alpha phellandrene affects the localization of TP53 protein | CTD | PMID:25649747 |
Tp53 | Rat | (-)-anisomycin | multiple interactions | EXP | | 6480464 | Anisomycin promotes the reaction [Colistin results in increased expression of TP53 protein] | CTD | PMID:28842171 |
Tp53 | Rat | (-)-citrinin | increases expression | ISO | RGD:70502 | 6480464 | Citrinin results in increased expression of TP53 protein | CTD | PMID:20929984 |
Tp53 | Rat | (-)-citrinin | increases expression | EXP | | 6480464 | Citrinin results in increased expression of TP53 protein modified form | CTD | PMID:22564900 |
Tp53 | Rat | (-)-citrinin | increases expression | ISO | RGD:11440 | 6480464 | Citrinin results in increased expression of TRP53 protein | CTD | PMID:21622943 |
Tp53 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:70502 | 6480464 | epigallocatechin gallate affects the reaction [Doxorubicin affects the expression of TP53 protein]; epigallocatechin gallate inhibits more ... | CTD | PMID:15657356|PMID:15764647|PMID:15795422|PMID:19406223|PMID:35218280 |
Tp53 | Rat | (-)-epigallocatechin 3-gallate | increases expression | ISO | RGD:70502 | 6480464 | epigallocatechin gallate results in increased expression of TP53 protein; epigallocatechin gallate results in increased expression more ... | CTD | PMID:26341291|PMID:32512070 |
Tp53 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | EXP | | 6480464 | [epigallocatechin gallate co-treated with coenzyme Q10] inhibits the reaction [Cisplatin results in increased phosphorylation of more ... | CTD | PMID:33393703 |
Tp53 | Rat | (-)-epigallocatechin 3-gallate | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to epigallocatechin gallate | CTD | PMID:15764647|PMID:23285096 |
Tp53 | Rat | (-)-epigallocatechin 3-gallate | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 mRNA affects the susceptibility to epigallocatechin gallate | CTD | PMID:19406223 |
Tp53 | Rat | (-)-epigallocatechin 3-gallate | affects expression | EXP | | 6480464 | epigallocatechin gallate affects the expression of TP53 protein | CTD | PMID:22000973 |
Tp53 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:11440 | 6480464 | [epigallocatechin gallate co-treated with Polylactic Acid-Polyglycolic Acid Copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in more ... | CTD | PMID:18656336|PMID:23717041|PMID:34600025 |
Tp53 | Rat | (-)-noscapine | increases expression | ISO | RGD:70502 | 6480464 | Noscapine results in increased expression of TP53 protein | CTD | PMID:20674069 |
Tp53 | Rat | (-)-noscapine | multiple interactions | ISO | RGD:70502 | 6480464 | Noscapine promotes the reaction [Cisplatin results in increased expression of TP53 protein]; Noscapine results in more ... | CTD | PMID:20674069|PMID:22848370 |
Tp53 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | RGD:11440 | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TRP53 mRNA | CTD | PMID:36331819 |
Tp53 | Rat | (1S)-bornane-2,3-dione | increases phosphorylation | ISO | RGD:70502 | 6480464 | camphorquinone results in increased phosphorylation of TP53 protein | CTD | PMID:26658076 |
Tp53 | Rat | (20R)-protopanaxadiol | increases expression | ISO | RGD:70502 | 6480464 | protopanaxadiol results in increased expression of TP53 mRNA; protopanaxadiol results in increased expression of TP53 more ... | CTD | PMID:31805304 |
Tp53 | Rat | (6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one | increases expression | ISO | RGD:11440 | 6480464 | cyclopiazonic acid results in increased expression of TRP53 mRNA | CTD | PMID:33400354 |
Tp53 | Rat | (9E,11E)-octadecadienoic acid | multiple interactions | ISO | RGD:70502 | 6480464 | 9,11-linoleic acid results in increased phosphorylation of and affects the localization of TP53 protein | CTD | PMID:15992797 |
Tp53 | Rat | (aminomethyl)phosphonic acid | increases expression | ISO | RGD:70502 | 6480464 | 1-aminomethylphosphonic acid results in increased expression of TP53 protein | CTD | PMID:23983455 |
Tp53 | Rat | (R)-adrenaline | decreases expression | ISO | RGD:11440 | 6480464 | Epinephrine results in decreased expression of TP53 protein | CTD | PMID:36423730 |
Tp53 | Rat | (R)-lipoic acid | multiple interactions | EXP | | 6480464 | Thioctic Acid inhibits the reaction [Methotrexate results in increased expression of TP53 protein] | CTD | PMID:19900424 |
Tp53 | Rat | (R)-noradrenaline | increases expression | EXP | | 6480464 | Norepinephrine results in increased expression of TP53 mRNA | CTD | PMID:14618266 |
Tp53 | Rat | (R,R,R)-alpha-tocopherol | multiple interactions | ISO | RGD:70502 | 6480464 | alpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 mRNA]; alpha-Tocopherol inhibits the more ... | CTD | PMID:12126965 |
Tp53 | Rat | (S)-colchicine | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the reaction [Colchicine results in increased phosphorylation of JUN protein]; TP53 protein more ... | CTD | PMID:12221076 |
Tp53 | Rat | (S)-naringenin | multiple interactions | ISO | RGD:70502 | 6480464 | [Tamoxifen co-treated with naringenin] results in increased expression of TP53 mRNA; naringenin inhibits the reaction more ... | CTD | PMID:15795422|PMID:27838343|PMID:30153467 |
Tp53 | Rat | (S)-naringenin | increases expression | ISO | RGD:70502 | 6480464 | naringenin results in increased expression of TP53 mRNA | CTD | PMID:30153467 |
Tp53 | Rat | (S)-nicotine | multiple interactions | ISO | RGD:70502 | 6480464 | 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [Nicotine results in decreased expression of TP53 protein]; [[Nicotine results in more ... | CTD | PMID:16601104|PMID:18805435|PMID:19139119|PMID:20727180|PMID:23907605|PMID:30272249 |
Tp53 | Rat | (S)-nicotine | increases expression | ISO | RGD:11440 | 6480464 | Nicotine results in increased expression of TRP53 mRNA; Nicotine results in increased expression of TRP53 more ... | CTD | PMID:30896085|PMID:31507073 |
Tp53 | Rat | (S)-nicotine | increases expression | ISO | RGD:70502 | 6480464 | Nicotine results in increased expression of TP53 protein | CTD | PMID:20727180 |
Tp53 | Rat | (S)-nicotine | decreases expression | ISO | RGD:70502 | 6480464 | Nicotine results in decreased expression of TP53 mRNA; Nicotine results in decreased expression of TP53 more ... | CTD | PMID:16011614|PMID:18247414|PMID:18805435|PMID:19139119|PMID:30272249 |
Tp53 | Rat | (S)-nicotine | decreases expression | ISO | RGD:11440 | 6480464 | Nicotine results in decreased expression of TRP53 protein | CTD | PMID:18835254 |
Tp53 | Rat | (S)-nicotine | multiple interactions | ISO | RGD:11440 | 6480464 | [Nicotine co-treated with Polylactic Acid-Polyglycolic Acid Copolymer] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression more ... | CTD | PMID:23933227|PMID:30896085 |
Tp53 | Rat | (S)-nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of TP53 mRNA | CTD | PMID:20339300|PMID:20426880 |
Tp53 | Rat | (S)-nicotine | affects response to substance | EXP | | 6480464 | TP53 protein affects the susceptibility to Nicotine | CTD | PMID:15983034 |
Tp53 | Rat | (S)-nicotine | affects expression | EXP | | 6480464 | Nicotine affects the expression of TP53 mRNA | CTD | PMID:10837795 |
Tp53 | Rat | (S)-ropivacaine | multiple interactions | EXP | | 6480464 | pifithrin inhibits the reaction [Ropivacaine results in increased expression of TP53 mRNA]; pifithrin inhibits the more ... | CTD | PMID:34091999 |
Tp53 | Rat | (S)-ropivacaine | increases expression | EXP | | 6480464 | Ropivacaine results in increased expression of TP53 mRNA; Ropivacaine results in increased expression of TP53 more ... | CTD | PMID:34091999 |
Tp53 | Rat | (Z)-3-butylidenephthalide | increases phosphorylation | ISO | RGD:70502 | 6480464 | butylidenephthalide results in increased phosphorylation of TP53 protein | CTD | PMID:16987298 |
Tp53 | Rat | (Z)-3-butylidenephthalide | increases expression | ISO | RGD:70502 | 6480464 | butylidenephthalide results in increased expression of TP53 protein | CTD | PMID:16987298 |
Tp53 | Rat | (Z)-ligustilide | multiple interactions | ISO | RGD:70502 | 6480464 | ligustilide results in decreased expression of and results in increased phosphorylation of TP53 protein | CTD | PMID:31765699 |
Tp53 | Rat | 1'-acetoxychavicol acetate | multiple interactions | ISO | RGD:70502 | 6480464 | [1'-acetoxychavicol acetate co-treated with Butyric Acid] results in increased phosphorylation of TP53 protein | CTD | PMID:24480522 |
Tp53 | Rat | 1,1'-azobis(N,N-dimethylformamide) | increases glutathionylation | ISO | RGD:70502 | 6480464 | Diamide results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | increases expression | EXP | | 6480464 | o,p'-DDT analog results in increased expression of TP53 mRNA; o,p'-DDT analog results in increased expression more ... | CTD | PMID:22937105 |
Tp53 | Rat | 1,1-dichloroethene | increases expression | ISO | RGD:11440 | 6480464 | vinylidene chloride results in increased expression of TRP53 protein | CTD | PMID:26682919 |
Tp53 | Rat | 1,10-phenanthroline | affects folding | ISO | RGD:11440 | 6480464 | 1,10-phenanthroline affects the folding of TRP53 protein | CTD | PMID:8467489 |
Tp53 | Rat | 1,10-phenanthroline | affects activity | ISO | RGD:70502 | 6480464 | 1,10-phenanthroline analog affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene | multiple interactions | ISO | RGD:11440 | 6480464 | [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... | CTD | PMID:25510870 |
Tp53 | Rat | 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene | decreases expression | ISO | RGD:70502 | 6480464 | 2,4,5,2',5'-pentachlorobiphenyl results in decreased expression of TP53 protein | CTD | PMID:19751709 |
Tp53 | Rat | 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene | multiple interactions | ISO | RGD:70502 | 6480464 | 2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 2,4,5,2',5'-pentachlorobiphenyl promotes the more ... | CTD | PMID:19751709|PMID:20840854 |
Tp53 | Rat | 1,2-dichloroethane | affects expression | ISO | RGD:11440 | 6480464 | ethylene dichloride affects the expression of TRP53 mRNA; ethylene dichloride affects the expression of TRP53 more ... | CTD | PMID:28973639 |
Tp53 | Rat | 1,2-dimethylhydrazine | decreases methylation | EXP | | 6480464 | 1,2-Dimethylhydrazine results in decreased methylation of TP53 exon | CTD | PMID:8863662 |
Tp53 | Rat | 1,2-dimethylhydrazine | affects expression | ISO | RGD:11440 | 6480464 | 1,2-Dimethylhydrazine affects the expression of TRP53 mRNA | CTD | PMID:22206623 |
Tp53 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:11440 | 6480464 | [NFE2L2 protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in increased expression of TRP53 mRNA | CTD | PMID:26388957 |
Tp53 | Rat | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1,2-Dimethylhydrazine results in increased expression of TP53 protein | CTD | PMID:18155637 |
Tp53 | Rat | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased methylation of TP53 exon]; Vanadium inhibits more ... | CTD | PMID:18155637|PMID:8863662 |
Tp53 | Rat | 1,3-Dinitropyrene | increases phosphorylation | ISO | RGD:11440 | 6480464 | 1,3-dinitropyrene results in increased phosphorylation of TRP53 protein | CTD | PMID:17240030 |
Tp53 | Rat | 1,3-Dinitropyrene | affects localization | ISO | RGD:11440 | 6480464 | 1,3-dinitropyrene affects the localization of TRP53 protein | CTD | PMID:17240030 |
Tp53 | Rat | 1,4-benzoquinone | increases expression | ISO | RGD:70502 | 6480464 | quinone results in increased expression of TP53 protein | CTD | PMID:20499891 |
Tp53 | Rat | 1,4-benzoquinone | increases expression | ISO | RGD:11440 | 6480464 | quinone analog results in increased expression of TRP53 protein modified form | CTD | PMID:33961949 |
Tp53 | Rat | 1,4-benzoquinone | multiple interactions | ISO | RGD:11440 | 6480464 | Acetylcysteine inhibits the reaction [quinone analog results in increased expression of TRP53 protein modified form]; more ... | CTD | PMID:33961949 |
Tp53 | Rat | 1,4-dithiothreitol | multiple interactions | ISO | RGD:70502 | 6480464 | Dithiothreitol inhibits the reaction [[Cadmium Chloride results in decreased activity of TP53 protein] inhibits the more ... | CTD | PMID:17555331|PMID:25446071 |
Tp53 | Rat | 1,8-Dinitropyrene | increases phosphorylation | ISO | RGD:11440 | 6480464 | 1,8-dinitropyrene results in increased phosphorylation of TRP53 protein | CTD | PMID:17240030 |
Tp53 | Rat | 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine | increases expression | ISO | RGD:11440 | 6480464 | Trimetazidine results in increased expression of TP53 protein | CTD | PMID:37591408 |
Tp53 | Rat | 1-hydroxy-1-norresistomycin | increases expression | ISO | RGD:70502 | 6480464 | 1-hydroxy-1-norresistomycin results in increased expression of TP53 mRNA; 1-hydroxy-1-norresistomycin results in increased expression of TP53 more ... | CTD | PMID:29596799 |
Tp53 | Rat | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | increases expression | ISO | RGD:11440 | 6480464 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TRP53 protein | CTD | PMID:23933227 |
Tp53 | Rat | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | RGD:11440 | 6480464 | [Nicotine co-treated with polylactic acid-polyglycolic acid copolymer] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression more ... | CTD | PMID:23933227 |
Tp53 | Rat | 1-methylphenanthrene | increases phosphorylation | EXP | | 6480464 | 1-methylphenanthrene results in increased phosphorylation of TP53 protein | CTD | PMID:17941746 |
Tp53 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of TP53 mRNA | CTD | PMID:17522070 |
Tp53 | Rat | 1-nitropyrene | multiple interactions | ISO | RGD:70502 | 6480464 | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased susceptibility to [Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene more ... | CTD | PMID:10837373|PMID:22044530 |
Tp53 | Rat | 1-nitropyrene | decreases expression | ISO | RGD:11440 | 6480464 | 1-nitropyrene results in decreased expression of TRP53 mRNA | CTD | PMID:11911274 |
Tp53 | Rat | 1-nitropyrene | affects localization | ISO | RGD:11440 | 6480464 | 1-nitropyrene affects the localization of TRP53 protein | CTD | PMID:17240030 |
Tp53 | Rat | 1-nitropyrene | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 affects the susceptibility to 1-nitropyrene | CTD | PMID:10837373 |
Tp53 | Rat | 1-nitropyrene | increases expression | ISO | RGD:70502 | 6480464 | 1-nitropyrene results in increased expression of TP53 protein; 1-nitropyrene results in increased expression of TP53 more ... | CTD | PMID:10837373|PMID:22044530 |
Tp53 | Rat | 1-nitropyrene | increases phosphorylation | ISO | RGD:11440 | 6480464 | 1-nitropyrene results in increased phosphorylation of TRP53 protein | CTD | PMID:17240030 |
Tp53 | Rat | 1-nitropyrene | increases expression | ISO | RGD:11440 | 6480464 | 1-nitropyrene results in increased expression of TRP53 mRNA | CTD | PMID:10928071|PMID:11911274 |
Tp53 | Rat | 1-nitropyrene | affects expression | EXP | | 6480464 | 1-nitropyrene affects the expression of TP53 mRNA | CTD | PMID:11201684 |
Tp53 | Rat | 11-deoxycorticosterone | multiple interactions | EXP | | 6480464 | [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein; acetovanillone inhibits the more ... | CTD | PMID:22431579 |
Tp53 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | RGD:11440 | 6480464 | Ethinyl Estradiol results in increased expression of TRP53 mRNA | CTD | PMID:17942748 |
Tp53 | Rat | 17alpha-ethynylestradiol | affects activity | ISO | RGD:70502 | 6480464 | Ethinyl Estradiol affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:11440 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TRP53 mRNA | CTD | PMID:17942748 |
Tp53 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of TP53 mRNA | CTD | PMID:16940010 |
Tp53 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | RGD:11440 | 6480464 | Ethinyl Estradiol affects the expression of TRP53 mRNA | CTD | PMID:17555576 |
Tp53 | Rat | 17beta-estradiol | multiple interactions | ISO | RGD:70502 | 6480464 | [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with Decitabine] results in increased expression more ... | CTD | PMID:15870704|PMID:16053526|PMID:17622325|PMID:18174961|PMID:22113133|PMID:22534328|PMID:24954032|PMID:31681507|PMID:36567042 |
Tp53 | Rat | 17beta-estradiol | decreases expression | ISO | RGD:70502 | 6480464 | Estradiol results in decreased expression of TP53 mRNA | CTD | PMID:31016752 |
Tp53 | Rat | 17beta-estradiol | decreases expression | ISO | RGD:11440 | 6480464 | Estradiol results in decreased expression of TRP53 protein | CTD | PMID:23684557 |
Tp53 | Rat | 17beta-estradiol | multiple interactions | ISO | RGD:11440 | 6480464 | Estradiol inhibits the reaction [TRP53 protein binds to CDKN1A promoter] | CTD | PMID:23684557 |
Tp53 | Rat | 17beta-estradiol | increases expression | ISO | RGD:70502 | 6480464 | Estradiol results in increased expression of TP53 mRNA; Estradiol results in increased expression of TP53 more ... | CTD | PMID:18174961|PMID:19647730|PMID:23804311|PMID:24481588|PMID:31681507 |
Tp53 | Rat | 17beta-estradiol | increases expression | ISO | RGD:11440 | 6480464 | Estradiol results in increased expression of TRP53 mRNA; Estradiol results in increased expression of TRP53 more ... | CTD | PMID:22314386 |
Tp53 | Rat | 17beta-estradiol | affects expression | ISO | RGD:70502 | 6480464 | Estradiol affects the expression of TP53 mRNA; Estradiol affects the expression of TRP53 mRNA | CTD | PMID:11896290|PMID:22574217 |
Tp53 | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of TP53 mRNA; Estradiol results in increased expression of TP53 more ... | CTD | PMID:14685795|PMID:17522070 |
Tp53 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with Methylnitrosourea co-treated with Progesterone] results in decreased expression of TP53 mRNA; Estradiol more ... | CTD | PMID:20732338|PMID:24894866|PMID:36567042 |
Tp53 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of TP53 protein | CTD | PMID:24894866 |
Tp53 | Rat | 17beta-estradiol 3-benzoate | increases expression | EXP | | 6480464 | estradiol 3-benzoate results in increased expression of TP53 mRNA; estradiol 3-benzoate results in increased expression more ... | CTD | PMID:24316378 |
Tp53 | Rat | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | Quercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of TP53 mRNA]; Quercetin inhibits more ... | CTD | PMID:24316378 |
Tp53 | Rat | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | multiple interactions | ISO | RGD:70502 | 6480464 | [Curcumin co-treated with Metribolone] results in increased phosphorylation of TP53 protein; TP53 protein inhibits the more ... | CTD | PMID:17202838|PMID:21134073 |
Tp53 | Rat | 19-Nor-17alpha-pregn-5(10)-en-20-yne-3alpha,17beta-diol | increases expression | EXP | | 6480464 | 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in increased expression of TP53 protein | CTD | PMID:16019103 |
Tp53 | Rat | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | multiple interactions | ISO | RGD:70502 | 6480464 | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one results in increased stability of and results in increased expression of and results in more ... | CTD | PMID:16288207 |
Tp53 | Rat | 1H-pyrazole | increases expression | ISO | RGD:11440 | 6480464 | pyrazole results in increased expression of TRP53 mRNA | CTD | PMID:17945193 |
Tp53 | Rat | 2'-Hydroxy-2,3,5'-trimethoxychalcone | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased expression of TP53 protein] | CTD | PMID:30408460 |
Tp53 | Rat | 2'-Hydroxy-2,3,5'-trimethoxychalcone | increases expression | ISO | RGD:70502 | 6480464 | 2-hydroxy-3',5,5'-trimethoxychalcone results in increased expression of TP53 protein | CTD | PMID:30408460 |
Tp53 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:70502 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene affects the localization of and results in increased expression of more ... | CTD | PMID:20840854|PMID:24954032 |
Tp53 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:11440 | 6480464 | [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... | CTD | PMID:25510870 |
Tp53 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | increases activity | ISO | RGD:70502 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl results in increased activity of TP53 protein | CTD | PMID:27589886 |
Tp53 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | EXP | | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of TP53 protein | CTD | PMID:33581290 |
Tp53 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | multiple interactions | ISO | RGD:11440 | 6480464 | [Flame Retardants results in increased abundance of 2,2',4,4'-tetrabromodiphenyl ether] which results in increased phosphorylation of more ... | CTD | PMID:38995820 |
Tp53 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of TP53 mRNA | CTD | PMID:27291303 |
Tp53 | Rat | 2,2',5,5'-Tetrachlorobenzidine | affects activity | ISO | RGD:70502 | 6480464 | 2,2',5,5'-tetrachlorobenzidine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | RGD:11440 | 6480464 | [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... | CTD | PMID:25510870 |
Tp53 | Rat | 2,2'-dithiodiethanol | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to 2-hydroxyethyl disulfide | CTD | PMID:22926048 |
Tp53 | Rat | 2,2,2-tetramine | multiple interactions | ISO | RGD:70502 | 6480464 | Paraquat promotes the reaction [Trientine results in increased phosphorylation of TP53 protein]; Trientine results in more ... | CTD | PMID:11369509|PMID:14513838 |
Tp53 | Rat | 2,2,2-tetramine | increases phosphorylation | ISO | RGD:70502 | 6480464 | Trientine results in increased phosphorylation of TP53 protein | CTD | PMID:11369509 |
Tp53 | Rat | 2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one | multiple interactions | ISO | RGD:70502 | 6480464 | 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one inhibits the reaction [TP53 protein mutant form binds to TP73 protein]; 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one promotes the more ... | CTD | PMID:21109480|PMID:21647879|PMID:23152798 |
Tp53 | Rat | 2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one | increases activity | ISO | RGD:70502 | 6480464 | 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one results in increased activity of TP53 protein; TP53 protein mutant form results in increased more ... | CTD | PMID:15860260|PMID:21647879 |
Tp53 | Rat | 2,3,4,6-tetrachlorophenol | affects activity | ISO | RGD:70502 | 6480464 | 2,3,4,6-tetrachlorophenol affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 2,3,5,6-tetrachlorophenol | affects activity | ISO | RGD:70502 | 6480464 | 2,3,5,6-tetrachlorophenate affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:11440 | 6480464 | Tetrachlorodibenzodioxin affects the expression of TRP53 mRNA | CTD | PMID:14708085|PMID:21570461|PMID:24058054|PMID:24680724 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:11440 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TRP53 mRNA; Tetrachlorodibenzodioxin results in increased expression of TRP53 more ... | CTD | PMID:14718646|PMID:15310856|PMID:15667827|PMID:17942748|PMID:21167638|PMID:33823233 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TP53 mRNA | CTD | PMID:22298810 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases phosphorylation | ISO | RGD:11440 | 6480464 | Tetrachlorodibenzodioxin results in increased phosphorylation of TRP53 protein | CTD | PMID:19085997 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TP53 mRNA | CTD | PMID:19520675|PMID:33387578 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases degradation | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased degradation of TP53 protein | CTD | PMID:15459018 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TP53 mRNA; Tetrachlorodibenzodioxin results in decreased expression of TP53 more ... | CTD | PMID:34747641|PMID:8640813 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of more ... | CTD | PMID:15093247|PMID:15459018 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Tetrachlorodibenzodioxin | CTD | PMID:10802220 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:11440 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TRP53 mRNA | CTD | PMID:17943652 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:11440 | 6480464 | [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of TRP53 mRNA; [Tetrachlorodibenzodioxin co-treated with Ethinyl more ... | CTD | PMID:14708085|PMID:17942748|PMID:21167638 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:70502 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TP53 mRNA; Tetrachlorodibenzodioxin results in decreased expression of TP53 more ... | CTD | PMID:17070097 |
Tp53 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:70502 | 6480464 | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased susceptibility to [Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene more ... | CTD | PMID:17070097|PMID:19578757|PMID:20299546|PMID:22044530|PMID:24954032 |
Tp53 | Rat | 2,4,4'-trichlorobiphenyl | multiple interactions | ISO | RGD:11440 | 6480464 | [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... | CTD | PMID:25510870 |
Tp53 | Rat | 2,4,4'-trichlorobiphenyl | multiple interactions | ISO | RGD:70502 | 6480464 | 2,4,4'-trichlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 2,4,4'-trichlorobiphenyl promotes the more ... | CTD | PMID:19751709|PMID:20840854 |
Tp53 | Rat | 2,4,6-trinitrobenzenesulfonic acid | multiple interactions | ISO | RGD:11440 | 6480464 | D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of TRP53 protein] | CTD | PMID:22427801 |
Tp53 | Rat | 2,4,6-trinitrobenzenesulfonic acid | multiple interactions | EXP | | 6480464 | Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in more ... | CTD | PMID:30503585 |
Tp53 | Rat | 2,4,6-trinitrobenzenesulfonic acid | increases expression | ISO | RGD:11440 | 6480464 | Trinitrobenzenesulfonic Acid results in increased expression of TRP53 protein | CTD | PMID:22427801 |
Tp53 | Rat | 2,4-D | multiple interactions | ISO | RGD:11440 | 6480464 | 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of more ... | CTD | PMID:33865415|PMID:37516258 |
Tp53 | Rat | 2,4-D | multiple interactions | EXP | | 6480464 | [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol more ... | CTD | PMID:36085217 |
Tp53 | Rat | 2,4-D | increases expression | ISO | RGD:11440 | 6480464 | 2,4-Dichlorophenoxyacetic Acid results in increased expression of TRP53 mRNA; 2,4-Dichlorophenoxyacetic Acid results in increased expression more ... | CTD | PMID:33865415 |
Tp53 | Rat | 2,4-dibromophenol | multiple interactions | ISO | RGD:11440 | 6480464 | 2,4-dibromophenol metabolite results in increased expression of and affects the localization of TRP53 protein; Acetylcysteine more ... | CTD | PMID:33961949 |
Tp53 | Rat | 2,4-dibromophenol | increases expression | ISO | RGD:11440 | 6480464 | 2,4-dibromophenol metabolite results in increased expression of TRP53 protein modified form | CTD | PMID:33961949 |
Tp53 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of TP53 mRNA | CTD | PMID:21346803 |
Tp53 | Rat | 2,6-di-tert-butyl-4-methylphenol | increases expression | EXP | | 6480464 | Butylated Hydroxytoluene results in increased expression of TP53 mRNA | CTD | PMID:9780227 |
Tp53 | Rat | 2,6-dichloroindophenol | multiple interactions | ISO | RGD:70502 | 6480464 | [2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased phosphorylation of TP53 protein | CTD | PMID:21034357 |
Tp53 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of TP53 mRNA | CTD | PMID:21346803 |
Tp53 | Rat | 2-acetamidofluorene | decreases expression | EXP | | 6480464 | 2-Acetylaminofluorene results in decreased expression of TP53 protein | CTD | PMID:19167416 |
Tp53 | Rat | 2-acetamidofluorene | increases expression | ISO | RGD:11440 | 6480464 | 2-Acetylaminofluorene results in increased expression of TRP53 protein | CTD | PMID:9667752 |
Tp53 | Rat | 2-acetamidofluorene | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein modified form results in increased susceptibility to 2-Acetylaminofluorene | CTD | PMID:17317680 |
Tp53 | Rat | 2-acetamidofluorene | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of BAX mRNA]; TRP53 more ... | CTD | PMID:17317680 |
Tp53 | Rat | 2-acetamidofluorene | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of TP53 protein; more ... | CTD | PMID:11003613|PMID:11915028|PMID:14633663|PMID:15565650|PMID:23665045 |
Tp53 | Rat | 2-acetamidofluorene | increases expression | ISO | RGD:70502 | 6480464 | 2-Acetylaminofluorene results in increased expression of TP53 protein | CTD | PMID:12888115 |
Tp53 | Rat | 2-acetamidofluorene | increases expression | EXP | | 6480464 | 2-Acetylaminofluorene results in increased expression of TP53 protein | CTD | PMID:10708481|PMID:15565650|PMID:7728945 |
Tp53 | Rat | 2-amino-4,6-dinitrotoluene | increases activity | ISO | RGD:70502 | 6480464 | 2-amino-4,6-dinitrotoluene results in increased activity of TP53 protein | CTD | PMID:14577614 |
Tp53 | Rat | 2-amino-4,6-dinitrotoluene | increases expression | ISO | RGD:70502 | 6480464 | 2-amino-4,6-dinitrotoluene results in increased expression of TP53 protein | CTD | PMID:14577614 |
Tp53 | Rat | 2-deoxy-D-glucose | multiple interactions | ISO | RGD:70502 | 6480464 | [Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in increased expression of TP53 mRNA; Deoxyglucose promotes the more ... | CTD | PMID:21042727|PMID:26079942 |
Tp53 | Rat | 2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid | multiple interactions | ISO | RGD:70502 | 6480464 | anacardic acid inhibits the reaction [[Fluorouracil results in increased acetylation of TP53 protein mutant form] more ... | CTD | PMID:26768552|PMID:27129209 |
Tp53 | Rat | 2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid | multiple interactions | ISO | RGD:11440 | 6480464 | [anacardic acid inhibits the reaction [Sodium Fluoride results in increased acetylation of TRP53 protein]] which more ... | CTD | PMID:31927229 |
Tp53 | Rat | 2-methoxyethanol | increases expression | EXP | | 6480464 | methyl cellosolve results in increased expression of TP53 mRNA | CTD | PMID:19643169 |
Tp53 | Rat | 2-naphthylamine | decreases expression | ISO | RGD:70502 | 6480464 | 2-Naphthylamine results in decreased expression of TP53 mRNA | CTD | PMID:18247414 |
Tp53 | Rat | 2-nitropropane | multiple interactions | ISO | RGD:11440 | 6480464 | APEX1 protein inhibits the reaction [2-nitropropane results in increased expression of TRP53 protein]; POLB protein more ... | CTD | PMID:12189182|PMID:19268524 |
Tp53 | Rat | 2-nitropropane | increases expression | ISO | RGD:11440 | 6480464 | 2-nitropropane results in increased expression of TRP53 protein | CTD | PMID:12189182|PMID:16720738|PMID:19268524 |
Tp53 | Rat | 2-nitrotoluene | increases mutagenesis | ISO | RGD:11440 | 6480464 | 2-nitrotoluene results in increased mutagenesis of TRP53 gene | CTD | PMID:13678655 |
Tp53 | Rat | 2-pyridylethylamine | multiple interactions | ISO | RGD:70502 | 6480464 | [Copper binds to Isatin binds to 2-(2-aminoethyl)pyridine] which results in increased expression of TP53 protein | CTD | PMID:17327230 |
Tp53 | Rat | 2-tert-butylhydroquinone | multiple interactions | EXP | | 6480464 | 2-tert-butylhydroquinone inhibits the reaction [Emodin results in increased expression of TP53 protein] | CTD | PMID:37393915 |
Tp53 | Rat | 2-tert-butylhydroquinone | increases expression | ISO | RGD:70502 | 6480464 | 2-tert-butylhydroquinone results in increased expression of TP53 protein | CTD | PMID:35123993 |
Tp53 | Rat | 2-tert-butylhydroquinone | multiple interactions | ISO | RGD:70502 | 6480464 | 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of TP53 protein] | CTD | PMID:35123993 |
Tp53 | Rat | 25-hydroxycholesterol | increases expression | ISO | RGD:70502 | 6480464 | 25-hydroxycholesterol results in increased expression of TP53 protein | CTD | PMID:39197811 |
Tp53 | Rat | 3',4',7-trihydroxyisoflavone | multiple interactions | ISO | RGD:70502 | 6480464 | 3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of TP53 mRNA]; Epirubicin promotes the more ... | CTD | PMID:22914566 |
Tp53 | Rat | 3',4',7-trihydroxyisoflavone | increases expression | ISO | RGD:70502 | 6480464 | 3',4',7-trihydroxyisoflavone results in increased expression of TP53 mRNA | CTD | PMID:22914566 |
Tp53 | Rat | 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | multiple interactions | EXP | | 6480464 | 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]; Melatonin inhibits more ... | CTD | PMID:14993511|PMID:17035936 |
Tp53 | Rat | 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | increases expression | EXP | | 6480464 | Puromycin Aminonucleoside results in increased expression of TP53 protein | CTD | PMID:14993511|PMID:15113391|PMID:16152783|PMID:17035936 |
Tp53 | Rat | 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | increases expression | ISO | RGD:11440 | 6480464 | Puromycin Aminonucleoside results in increased expression of TRP53 protein | CTD | PMID:15987750|PMID:17035936 |
Tp53 | Rat | 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | multiple interactions | ISO | RGD:11440 | 6480464 | 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TRP53 protein]; Dexamethasone inhibits more ... | CTD | PMID:15987750|PMID:17035936 |
Tp53 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | ISO | RGD:70502 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TP53 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TP53 more ... | CTD | PMID:19751709|PMID:21703328 |
Tp53 | Rat | 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | ISO | RGD:70502 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene affects the localization of TP53 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction more ... | CTD | PMID:19751709|PMID:20840854 |
Tp53 | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | EXP | | 6480464 | tetrabromobisphenol A results in increased expression of TP53 mRNA | CTD | PMID:28970181 |
Tp53 | Rat | 3,3',5,5'-tetrabromobisphenol A | multiple interactions | ISO | RGD:11440 | 6480464 | [Flame Retardants results in increased abundance of tetrabromobisphenol A] which results in increased phosphorylation of more ... | CTD | PMID:38995820 |
Tp53 | Rat | 3,3',5,5'-tetrabromobisphenol A | increases mutagenesis | EXP | | 6480464 | tetrabromobisphenol A results in increased mutagenesis of TP53 gene | CTD | PMID:26353976 |
Tp53 | Rat | 3,3',5,5'-tetraiodothyroacetic acid | multiple interactions | EXP | | 6480464 | tetraiodothyroacetic acid inhibits the reaction [Thyroxine affects the localization of TP53 protein modified form] | CTD | PMID:17984113 |
Tp53 | Rat | 3,3',5,5'-tetraiodothyroacetic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [heteronemin affects the susceptibility to tetraiodothyroacetic acid] which results in decreased expression of TP53 mRNA; more ... | CTD | PMID:35151786 |
Tp53 | Rat | 3,3',5,5'-tetraiodothyroacetic acid | decreases expression | ISO | RGD:70502 | 6480464 | tetraiodothyroacetic acid results in decreased expression of TP53 mRNA | CTD | PMID:35151786 |
Tp53 | Rat | 3,3'-Dichlorobenzidine | affects activity | ISO | RGD:70502 | 6480464 | 3,3'-Dichlorobenzidine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 3,3'-diindolylmethane | multiple interactions | ISO | RGD:70502 | 6480464 | 3,3'-diindolylmethane results in increased expression of and results in increased phosphorylation of and results in more ... | CTD | PMID:22290291 |
Tp53 | Rat | 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine | decreases expression | ISO | RGD:70502 | 6480464 | 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine results in decreased expression of TP53 mRNA | CTD | PMID:23810796 |
Tp53 | Rat | 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine | increases expression | ISO | RGD:70502 | 6480464 | 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine results in increased expression of TP53 protein | CTD | PMID:23810796 |
Tp53 | Rat | 3,6-diaminoacridine | increases activity | ISO | RGD:70502 | 6480464 | Proflavine results in increased activity of TP53 protein | CTD | PMID:30818834 |
Tp53 | Rat | 3,6-diaminoacridine | affects activity | ISO | RGD:70502 | 6480464 | Proflavine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 3,7-dihydropurine-6-thione | affects activity | ISO | RGD:70502 | 6480464 | Mercaptopurine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione | multiple interactions | ISO | RGD:70502 | 6480464 | bisindolylmaleimide I results in decreased degradation of and results in increased expression of TP53 protein | CTD | PMID:16055726 |
Tp53 | Rat | 3-aminobenzamide | multiple interactions | ISO | RGD:70502 | 6480464 | 3-aminobenzamide inhibits the reaction [Capsaicin results in increased expression of TP53 protein]; 3-aminobenzamide inhibits the more ... | CTD | PMID:22226932 |
Tp53 | Rat | 3-BROMO-7-NITROINDAZOLE | multiple interactions | ISO | RGD:11440 | 6480464 | 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TRP53 protein] | CTD | PMID:23985028 |
Tp53 | Rat | 3-bromopyruvic acid | multiple interactions | ISO | RGD:70502 | 6480464 | bromopyruvate promotes the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]; SOD1 protein inhibits more ... | CTD | PMID:21548882 |
Tp53 | Rat | 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone | increases mutagenesis | EXP | | 6480464 | 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone results in increased mutagenesis of TP53 gene | CTD | PMID:11152562 |
Tp53 | Rat | 3-chloropropane-1,2-diol | increases expression | ISO | RGD:70502 | 6480464 | alpha-Chlorohydrin results in increased expression of TP53 protein | CTD | PMID:28070108 |
Tp53 | Rat | 3-hydroxybutyric acid | multiple interactions | ISO | RGD:70502 | 6480464 | 3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in increased acetylation of TP53 more ... | CTD | PMID:25440059 |
Tp53 | Rat | 3-iodoprop-2-yn-1-yl butylcarbamate | affects activity | ISO | RGD:70502 | 6480464 | 3-iodo-2-propynylbutylcarbamate affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 3-methyladenine | multiple interactions | ISO | RGD:70502 | 6480464 | 3-methyladenine inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased more ... | CTD | PMID:22927544|PMID:23380477|PMID:30555576 |
Tp53 | Rat | 3-methyladenine | multiple interactions | ISO | RGD:11440 | 6480464 | 3-methyladenine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TRP53 more ... | CTD | PMID:30555576 |
Tp53 | Rat | 3-methylcholanthrene | multiple interactions | ISO | RGD:11440 | 6480464 | Methylcholanthrene promotes the reaction [TRP53 protein binds to ABCB1B promoter]; Methylcholanthrene promotes the reaction [TRP53 more ... | CTD | PMID:11096091|PMID:20570689 |
Tp53 | Rat | 3-methylcholanthrene | increases expression | EXP | | 6480464 | Methylcholanthrene results in increased expression of TP53 mRNA | CTD | PMID:23273579 |
Tp53 | Rat | 3-methylfuran | decreases expression | EXP | | 6480464 | 3-methylfuran results in decreased expression of TP53 mRNA | CTD | PMID:38160780 |
Tp53 | Rat | 3-Nitrobenzanthrone | decreases expression | ISO | RGD:70502 | 6480464 | 3-nitrobenzanthrone results in decreased expression of TP53 mRNA; 3-nitrobenzanthrone results in decreased expression of TP53 more ... | CTD | PMID:34036453 |
Tp53 | Rat | 3-Nitrobenzanthrone | increases mutagenesis | ISO | RGD:70502 | 6480464 | 3-nitrobenzanthrone results in increased mutagenesis of TP53 gene | CTD | PMID:18765419 |
Tp53 | Rat | 3-Nitrobenzanthrone | increases expression | ISO | RGD:11440 | 6480464 | 3-nitrobenzanthrone results in increased expression of TRP53 protein | CTD | PMID:25230394 |
Tp53 | Rat | 3-Nitrofluoranthene | multiple interactions | ISO | RGD:11440 | 6480464 | 3-nitrofluoranthene results in increased phosphorylation of and affects the localization of TRP53 protein | CTD | PMID:19041363 |
Tp53 | Rat | 3-phenylprop-2-enal | decreases expression | ISO | RGD:70502 | 6480464 | cinnamaldehyde results in decreased expression of TP53 mRNA | CTD | PMID:17178418 |
Tp53 | Rat | 4'-epidoxorubicin | multiple interactions | ISO | RGD:70502 | 6480464 | 3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of TP53 mRNA]; [Epirubicin analog co-treated more ... | CTD | PMID:22914566|PMID:26335193 |
Tp53 | Rat | 4'-epidoxorubicin | increases expression | ISO | RGD:70502 | 6480464 | Epirubicin results in increased expression of TP53 mRNA | CTD | PMID:22914566|PMID:26335193 |
Tp53 | Rat | 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid | multiple interactions | ISO | RGD:70502 | 6480464 | 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein] | CTD | PMID:10951577 |
Tp53 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:11440 | 6480464 | bisphenol S results in increased expression of TRP53 mRNA | CTD | PMID:32742594|PMID:39298647 |
Tp53 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | RGD:70502 | 6480464 | bisphenol S results in decreased methylation of TP53 gene | CTD | PMID:38338858 |
Tp53 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:70502 | 6480464 | bisphenol S results in increased expression of TP53 mRNA; bisphenol S results in increased expression more ... | CTD | PMID:36565802 |
Tp53 | Rat | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | multiple interactions | ISO | RGD:70502 | 6480464 | 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TP53 protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone inhibits the more ... | CTD | PMID:18805435|PMID:19931552 |
Tp53 | Rat | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | increases expression | ISO | RGD:70502 | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TP53 protein | CTD | PMID:19931552|PMID:21776270|PMID:26231820 |
Tp53 | Rat | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | multiple interactions | ISO | RGD:11440 | 6480464 | [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of TRP53 mRNA | CTD | PMID:21167638 |
Tp53 | Rat | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | increases ADP-ribosylation | ISO | RGD:70502 | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased ADP-ribosylation of TP53 protein | CTD | PMID:20421341 |
Tp53 | Rat | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | increases phosphorylation | ISO | RGD:70502 | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of TP53 protein | CTD | PMID:20421341 |
Tp53 | Rat | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | decreases expression | ISO | RGD:70502 | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TP53 protein | CTD | PMID:18805435 |
Tp53 | Rat | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | affects localization | ISO | RGD:70502 | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone affects the localization of TP53 protein | CTD | PMID:19931552|PMID:20421341 |
Tp53 | Rat | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2,6-dinitrotoluene affects the expression of TP53 mRNA | CTD | PMID:21346803 |
Tp53 | Rat | 4-Aminobenzamide | multiple interactions | ISO | RGD:11440 | 6480464 | 4-aminobenzamide promotes the reaction [Acetaminophen results in decreased expression of TRP53 protein] | CTD | PMID:11461765 |
Tp53 | Rat | 4-aminofolic acid | affects activity | ISO | RGD:70502 | 6480464 | Aminopterin affects the activity of TP53 protein; Aminopterin metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 4-chloroaniline | affects expression | ISO | RGD:70502 | 6480464 | 4-chloroaniline affects the expression of TP53 mRNA | CTD | PMID:27825931 |
Tp53 | Rat | 4-hydroperoxycyclophosphamide | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [perfosfamide results in increased expression of TP53] | CTD | PMID:18034189 |
Tp53 | Rat | 4-hydroperoxycyclophosphamide | multiple interactions | ISO | RGD:11440 | 6480464 | perfosfamide results in increased expression of and results in increased phosphorylation of and results in more ... | CTD | PMID:17068108 |
Tp53 | Rat | 4-hydroperoxycyclophosphamide | increases expression | ISO | RGD:70502 | 6480464 | perfosfamide results in increased expression of TP53 | CTD | PMID:18034189 |
Tp53 | Rat | 4-hydroxy-TEMPO | increases expression | ISO | RGD:70502 | 6480464 | tempol results in increased expression of TP53 protein | CTD | PMID:15601469 |
Tp53 | Rat | 4-hydroxynon-2-enal | increases mutagenesis | ISO | RGD:70502 | 6480464 | 4-hydroxy-2-nonenal results in increased mutagenesis of TP53 gene | CTD | PMID:11050162 |
Tp53 | Rat | 4-hydroxynon-2-enal | affects abundance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the abundance of 4-hydroxy-2-nonenal | CTD | PMID:22229939 |
Tp53 | Rat | 4-hydroxynon-2-enal | increases expression | ISO | RGD:70502 | 6480464 | 4-hydroxy-2-nonenal results in increased expression of TP53 mRNA; 4-hydroxy-2-nonenal results in increased expression of TP53 more ... | CTD | PMID:15607904 |
Tp53 | Rat | 4-hydroxyphenyl retinamide | affects expression | ISO | RGD:70502 | 6480464 | Fenretinide affects the expression of TP53 | CTD | PMID:16720286 |
Tp53 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:70502 | 6480464 | Fenretinide results in increased expression of TP53 mRNA; Fenretinide results in increased expression of TP53 more ... | CTD | PMID:16540676|PMID:16570282|PMID:17159502|PMID:17216584 |
Tp53 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:70502 | 6480464 | Fenretinide results in decreased expression of TP53 mRNA | CTD | PMID:7811993 |
Tp53 | Rat | 4-methylumbelliferone | affects activity | ISO | RGD:70502 | 6480464 | Hymecromone affects the activity of TP53 protein; Hymecromone metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 4-Nerolidylcatechol | increases expression | ISO | RGD:70502 | 6480464 | 4-nerolidylcatechol results in increased expression of TP53 protein | CTD | PMID:22372875|PMID:32334110 |
Tp53 | Rat | 4-nitrophenol | affects glucuronidation | ISO | RGD:70502 | 6480464 | TP53 protein affects the glucuronidation of 4-nitrophenol | CTD | PMID:11695553 |
Tp53 | Rat | 4-nitroquinoline N-oxide | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to 4-Nitroquinoline-1-oxide | CTD | PMID:16543248 |
Tp53 | Rat | 4-nitroquinoline N-oxide | increases expression | ISO | RGD:70502 | 6480464 | 4-Nitroquinoline-1-oxide results in increased expression of TP53 protein | CTD | PMID:32087850 |
Tp53 | Rat | 4-nitroquinoline N-oxide | decreases expression | EXP | | 6480464 | 4-Nitroquinoline-1-oxide results in decreased expression of TP53 protein | CTD | PMID:20599846 |
Tp53 | Rat | 4-nonylphenol | increases expression | EXP | | 6480464 | 4-nonylphenol results in increased expression of TP53 mRNA; 4-nonylphenol results in increased expression of TP53 more ... | CTD | PMID:27087316|PMID:27109770 |
Tp53 | Rat | 4-nonylphenol | increases phosphorylation | ISO | RGD:70502 | 6480464 | 4-nonylphenol results in increased phosphorylation of TP53 protein | CTD | PMID:32466334 |
Tp53 | Rat | 4-phenylbutyric acid | multiple interactions | EXP | | 6480464 | 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of TP53 protein] | CTD | PMID:30980806 |
Tp53 | Rat | 4-tert-Octylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of TP53 mRNA | CTD | PMID:17011747 |
Tp53 | Rat | 4-tert-Octylphenol | increases phosphorylation | ISO | RGD:70502 | 6480464 | 4-tert-octylphenol results in increased phosphorylation of TP53 protein | CTD | PMID:32466334 |
Tp53 | Rat | 5'-S-methyl-5'-thioadenosine | increases expression | ISO | RGD:70502 | 6480464 | 5'-methylthioadenosine results in increased expression of TP53 protein | CTD | PMID:31712395 |
Tp53 | Rat | 5,6,7,8-tetrahydrobiopterin | multiple interactions | ISO | RGD:70502 | 6480464 | sapropterin inhibits the reaction [Methotrexate results in increased expression of TP53 protein] | CTD | PMID:22183962 |
Tp53 | Rat | 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole | increases phosphorylation | ISO | RGD:70502 | 6480464 | Dichlororibofuranosylbenzimidazole results in increased phosphorylation of TP53 protein | CTD | PMID:24102143 |
Tp53 | Rat | 5-(2-chloroethyl)-4-methylthiazole | multiple interactions | EXP | | 6480464 | Chlormethiazole inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein] | CTD | PMID:16330492 |
Tp53 | Rat | 5-aminolevulinic acid | increases expression | ISO | RGD:70502 | 6480464 | Aminolevulinic Acid analog results in increased expression of TP53 | CTD | PMID:17311614 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | multiple interactions | ISO | RGD:70502 | 6480464 | [Decitabine affects the methylation of BAX gene] affects the reaction [TP53 protein results in increased more ... | CTD | PMID:14722112|PMID:15753979|PMID:17133271|PMID:17389721|PMID:17977830|PMID:18223691|PMID:18608210|PMID:18992151|PMID:19010910|PMID:19037090|PMID:19363521|PMID:22534328|PMID:23300844 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | increases phosphorylation | ISO | RGD:70502 | 6480464 | Decitabine results in increased phosphorylation of TP53 protein | CTD | PMID:18636160|PMID:19732952 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | decreases ubiquitination | ISO | RGD:70502 | 6480464 | Decitabine results in decreased ubiquitination of TP53 protein | CTD | PMID:17977830 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | decreases methylation | ISO | RGD:70502 | 6480464 | Decitabine results in decreased methylation of TP53 promoter | CTD | PMID:19037090 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | increases acetylation | ISO | RGD:70502 | 6480464 | Decitabine results in increased acetylation of TP53 protein | CTD | PMID:17977830 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | increases expression | EXP | | 6480464 | Decitabine results in increased expression of TP53 mRNA | CTD | PMID:21449042 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | affects localization | ISO | RGD:70502 | 6480464 | Decitabine affects the localization of TP53 protein; Decitabine affects the localization of TP53 protein modified more ... | CTD | PMID:17991895|PMID:19037090 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:11440 | 6480464 | Decitabine results in increased expression of TRP53 mRNA | CTD | PMID:27915011 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:70502 | 6480464 | Decitabine results in increased expression of TP53 mRNA; Decitabine results in increased expression of TP53 more ... | CTD | PMID:15753979|PMID:16025287|PMID:17785578|PMID:17977830|PMID:19037090|PMID:19037991|PMID:19950695|PMID:20480522|PMID:22534328|PMID:36318118 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | increases activity | ISO | RGD:70502 | 6480464 | Decitabine results in increased activity of TP53 protein | CTD | PMID:30818834 |
Tp53 | Rat | 5-aza-2'-deoxycytidine | decreases methylation | EXP | | 6480464 | Decitabine results in decreased methylation of TP53 promoter | CTD | PMID:21449042 |
Tp53 | Rat | 5-azacytidine | increases expression | EXP | | 6480464 | Azacitidine results in increased expression of TP53 mRNA; Azacitidine results in increased expression of TP53 more ... | CTD | PMID:16427046 |
Tp53 | Rat | 5-azacytidine | affects activity | ISO | RGD:70502 | 6480464 | Azacitidine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 5-chloro-7-iodoquinolin-8-ol | multiple interactions | ISO | RGD:70502 | 6480464 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Clioquinol results in increased phosphorylation of TP53 protein] | CTD | PMID:22627294 |
Tp53 | Rat | 5-chloro-7-iodoquinolin-8-ol | increases phosphorylation | ISO | RGD:70502 | 6480464 | Clioquinol results in increased phosphorylation of TP53 protein | CTD | PMID:22627294 |
Tp53 | Rat | 5-fluorouracil | increases expression | ISO | RGD:11440 | 6480464 | Fluorouracil results in increased expression of TRP53 protein | CTD | PMID:16949053|PMID:31288002|PMID:35101590|PMID:9050858 |
Tp53 | Rat | 5-fluorouracil | affects activity | ISO | RGD:70502 | 6480464 | Fluorouracil affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 5-fluorouracil | multiple interactions | ISO | RGD:11440 | 6480464 | Fluorouracil promotes the reaction [Luteolin results in increased expression of TRP53 protein]; Luteolin promotes the more ... | CTD | PMID:31288002 |
Tp53 | Rat | 5-fluorouracil | increases acetylation | ISO | RGD:70502 | 6480464 | Fluorouracil results in increased acetylation of TP53 protein mutant form | CTD | PMID:27129209 |
Tp53 | Rat | 5-fluorouracil | increases phosphorylation | ISO | RGD:70502 | 6480464 | Fluorouracil results in increased phosphorylation of TP53 protein | CTD | PMID:15489892|PMID:17971768|PMID:19010883|PMID:25744307 |
Tp53 | Rat | 5-fluorouracil | affects phosphorylation | ISO | RGD:70502 | 6480464 | Fluorouracil affects the phosphorylation of TP53 protein | CTD | PMID:23941782 |
Tp53 | Rat | 5-fluorouracil | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 promoter mutant form results in decreased susceptibility to Fluorouracil | CTD | PMID:22445862 |
Tp53 | Rat | 5-fluorouracil | decreases expression | ISO | RGD:70502 | 6480464 | Fluorouracil results in decreased expression of TP53 mRNA | CTD | PMID:16709241|PMID:18930000 |
Tp53 | Rat | 5-fluorouracil | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 results in increased susceptibility to Fluorouracil | CTD | PMID:9050858 |
Tp53 | Rat | 5-fluorouracil | increases activity | ISO | RGD:11440 | 6480464 | Fluorouracil results in increased activity of TRP53 protein | CTD | PMID:16949053 |
Tp53 | Rat | 5-fluorouracil | increases expression | EXP | | 6480464 | Fluorouracil results in increased expression of TP53 protein; Fluorouracil results in increased expression of TRP53 more ... | CTD | PMID:15459018|PMID:35101590 |
Tp53 | Rat | 5-fluorouracil | multiple interactions | EXP | | 6480464 | ferrostatin-1 inhibits the reaction [Fluorouracil results in increased expression of TRP53 protein]; Fluorouracil promotes the more ... | CTD | PMID:15459018|PMID:16330492|PMID:35101590 |
Tp53 | Rat | 5-fluorouracil | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Fluorouracil; TP53 results in increased susceptibility to Fluorouracil | CTD | PMID:14646558|PMID:14704126|PMID:16686938 |
Tp53 | Rat | 5-fluorouracil | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 gene polymorphism affects the susceptibility to Fluorouracil; TP53 protein affects the susceptibility to Fluorouracil | CTD | PMID:14665630|PMID:15041737|PMID:15534911|PMID:15608686|PMID:17339891|PMID:18498133|PMID:18600534|PMID:22525470 |
Tp53 | Rat | 5-fluorouracil | increases expression | ISO | RGD:70502 | 6480464 | Fluorouracil results in increased expression of TP53; Fluorouracil results in increased expression of TP53 mRNA; more ... | CTD | PMID:11750847|PMID:12082016|PMID:12792779|PMID:14646558|PMID:14665630|PMID:15016801|PMID:15546879|PMID:15865071|PMID:15896711|PMID:16584549|PMID:16709241|PMID:16963839|PMID:17056233|PMID:17699798|PMID:19015155|PMID:19098008|PMID:22445862|PMID:23056627|PMID:23941782|PMID:26544897|PMID:27129209|PMID:29879413|PMID:30177839|PMID:34151400|PMID:9192825 |
Tp53 | Rat | 5-fluorouracil | increases activity | ISO | RGD:70502 | 6480464 | Fluorouracil results in increased activity of TP53 protein | CTD | PMID:18779317|PMID:19010883 |
Tp53 | Rat | 5-fluorouracil | decreases degradation | ISO | RGD:70502 | 6480464 | Fluorouracil results in decreased degradation of TP53 protein | CTD | PMID:15625077 |
Tp53 | Rat | 5-fluorouracil | multiple interactions | ISO | RGD:70502 | 6480464 | [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to more ... | CTD | PMID:14665630|PMID:15016801|PMID:15152939|PMID:15161716|PMID:15254702|PMID:15489892|PMID:15546879|PMID:15625077|PMID:15896711|PMID:15999354|PMID:16077963|PMID:16168113|PMID:16557594|PMID:16963839|PMID:17634554|PMID:17637740|PMID:17699798|PMID:17971768|PMID:17982676|PMID:18497562|PMID:18600534|PMID:18698031|PMID:18779317|PMID:18930000|PMID:19097688|PMID:19106633|PMID:20367642|PMID:21205074|PMID:22966307|PMID:23941782|PMID:25744307|PMID:26544897|PMID:27129209|PMID:32800223 |
Tp53 | Rat | 5-Geranyloxy-7-methoxycoumarin | increases phosphorylation | ISO | RGD:70502 | 6480464 | 5-geranyloxy-7-methoxycoumarin results in increased phosphorylation of TRP53 protein | CTD | PMID:23345169 |
Tp53 | Rat | 5-methoxypsoralen | multiple interactions | ISO | RGD:70502 | 6480464 | 5-Methoxypsoralen results in increased expression of and results in increased phosphorylation of TP53 protein | CTD | PMID:30576070 |
Tp53 | Rat | 5-methoxypsoralen | affects activity | ISO | RGD:70502 | 6480464 | 5-Methoxypsoralen metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide | increases acetylation | ISO | RGD:70502 | 6480464 | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased acetylation of TP53 protein | CTD | PMID:24726431|PMID:29545174 |
Tp53 | Rat | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide | increases acetylation | EXP | | 6480464 | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased acetylation of TP53 protein | CTD | PMID:35307491 |
Tp53 | Rat | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide | multiple interactions | EXP | | 6480464 | [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide co-treated with [Potassium Dichromate results in increased abundance of chromium hexavalent ion]] results in more ... | CTD | PMID:35307491 |
Tp53 | Rat | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide | increases acetylation | ISO | RGD:11440 | 6480464 | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased acetylation of TRP53 protein | CTD | PMID:21593185|PMID:32017914 |
Tp53 | Rat | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide | multiple interactions | ISO | RGD:11440 | 6480464 | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Cisplatin results in increased acetylation of TRP53 more ... | CTD | PMID:21593185|PMID:24040102|PMID:25665036 |
Tp53 | Rat | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide | multiple interactions | ISO | RGD:70502 | 6480464 | Camptothecin inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased acetylation of TP53 protein] | CTD | PMID:24726431 |
Tp53 | Rat | 6-O-methylguanine | multiple interactions | ISO | RGD:70502 | 6480464 | [O(6)-benzylguanine results in increased susceptibility to O-(6)-methylguanine] which results in increased expression of TP53 mRNA more ... | CTD | PMID:29666243 |
Tp53 | Rat | 6-oxocampestanol | increases expression | ISO | RGD:70502 | 6480464 | 6-oxocampestanol results in increased expression of TP53 protein | CTD | PMID:32001316 |
Tp53 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TP53 mRNA | CTD | PMID:24780913 |
Tp53 | Rat | 7,12-dimethyltetraphene | multiple interactions | ISO | RGD:11440 | 6480464 | [9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in increased activity of TRP53 protein; [Butyric Acid co-treated with more ... | CTD | PMID:20043298|PMID:22009531|PMID:23717041|PMID:25478867|PMID:33347706|PMID:35908932 |
Tp53 | Rat | 7,12-dimethyltetraphene | increases phosphorylation | ISO | RGD:11440 | 6480464 | 9,10-Dimethyl-1,2-benzanthracene results in increased phosphorylation of TRP53 protein | CTD | PMID:35908932 |
Tp53 | Rat | 7,12-dimethyltetraphene | multiple interactions | EXP | | 6480464 | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 protein]; more ... | CTD | PMID:30101532|PMID:34896434|PMID:39214269 |
Tp53 | Rat | 7,12-dimethyltetraphene | increases expression | EXP | | 6480464 | 9,10-Dimethyl-1,2-benzanthracene results in increased expression of TP53 mRNA | CTD | PMID:24269759 |
Tp53 | Rat | 7,12-dimethyltetraphene | decreases expression | EXP | | 6480464 | 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 more ... | CTD | PMID:24269759|PMID:30101532|PMID:34896434|PMID:39214269 |
Tp53 | Rat | 7,12-dimethyltetraphene | increases expression | ISO | RGD:11440 | 6480464 | 9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of TRP53 protein modified form; 9,10-Dimethyl-1,2-benzanthracene results in increased more ... | CTD | PMID:12734332|PMID:20043298|PMID:23717041|PMID:25478867|PMID:32553695 |
Tp53 | Rat | 7,12-dimethyltetraphene | decreases expression | ISO | RGD:11440 | 6480464 | 9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TRP53 mRNA | CTD | PMID:33347706 |
Tp53 | Rat | 7,12-dimethyltetraphene | increases activity | ISO | RGD:70502 | 6480464 | 9,10-Dimethyl-1,2-benzanthracene results in increased activity of TP53 protein | CTD | PMID:20655369 |
Tp53 | Rat | 7,12-dimethyltetraphene | multiple interactions | ISO | RGD:70502 | 6480464 | 2,4,3',5'-tetramethoxystilbene inhibits the reaction [[CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene] which results in more ... | CTD | PMID:22009531|PMID:32553695 |
Tp53 | Rat | 7,8-diacetoxy-4-methylcoumarin | increases expression | ISO | RGD:70502 | 6480464 | 7,8-diacetoxy-4-methylcoumarin results in increased expression of TP53 protein | CTD | PMID:19061872 |
Tp53 | Rat | 7,9-dihydro-1H-purine-2,6,8(3H)-trione | increases phosphorylation | ISO | RGD:11440 | 6480464 | Uric Acid results in increased phosphorylation of TRP53 protein | CTD | PMID:23619996 |
Tp53 | Rat | 7-amino-4-hydroxy-2-naphthalenesulfonic acid | affects activity | ISO | RGD:70502 | 6480464 | 7-amino-4-hydroxy-2-naphthalenesulfonic acid affects the activity of TP53 protein; 7-amino-4-hydroxy-2-naphthalenesulfonic acid metabolite affects the activity of more ... | CTD | PMID:35435491 |
Tp53 | Rat | 7-ketocholesterol | increases expression | EXP | | 6480464 | 7-ketocholesterol results in increased expression of TP53 protein | CTD | PMID:25845326 |
Tp53 | Rat | 7-ketocholesterol | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of TP53 protein]; BAY 11-7085 inhibits more ... | CTD | PMID:25845326 |
Tp53 | Rat | 7-nitroindazole | multiple interactions | EXP | | 6480464 | [7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat results in more ... | CTD | PMID:20478973 |
Tp53 | Rat | 8-Br-cAMP | increases expression | ISO | RGD:70502 | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TP53; 8-Bromo Cyclic Adenosine Monophosphate results more ... | CTD | PMID:10642304|PMID:11802967 |
Tp53 | Rat | 8-bromo-3',5'-cyclic GMP | increases expression | EXP | | 6480464 | 8-bromocyclic GMP results in increased expression of TP53 protein | CTD | PMID:9888876 |
Tp53 | Rat | 9,10-phenanthroquinone | affects localization | ISO | RGD:70502 | 6480464 | 9,10-phenanthrenequinone affects the localization of TP53 protein | CTD | PMID:29108775 |
Tp53 | Rat | 9,11,13-octadecatrienoic acid | increases expression | ISO | RGD:70502 | 6480464 | eleostearic acid results in increased expression of TP53 protein | CTD | PMID:15961301 |
Tp53 | Rat | 9-aminoacridine | multiple interactions | ISO | RGD:70502 | 6480464 | Aminacrine results in increased stability of and results in increased activity of TP53 protein | CTD | PMID:16177561 |
Tp53 | Rat | 9-aminoacridine | affects activity | ISO | RGD:70502 | 6480464 | Aminacrine analog affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | 9-Methoxycamptothecin | increases expression | ISO | RGD:70502 | 6480464 | 9-methoxycamptothecin results in increased expression of TP53 mRNA; 9-methoxycamptothecin results in increased expression of TP53 more ... | CTD | PMID:23369935 |
Tp53 | Rat | ABT-737 | multiple interactions | ISO | RGD:70502 | 6480464 | [ABT-737 co-treated with hydroquinone] results in increased expression of TRP53 protein | CTD | PMID:28843007 |
Tp53 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of TP53 mRNA | CTD | PMID:31881176 |
Tp53 | Rat | acetamiprid | increases expression | ISO | RGD:11440 | 6480464 | acetamiprid results in increased expression of TP53 protein | CTD | PMID:36457797 |
Tp53 | Rat | acetic acid | decreases expression | ISO | RGD:70502 | 6480464 | Acetic Acid results in decreased expression of TP53 mRNA | CTD | PMID:35750087 |
Tp53 | Rat | acetylsalicylic acid | increases acetylation | ISO | RGD:70502 | 6480464 | Aspirin results in increased acetylation of TP53 protein | CTD | PMID:19212664 |
Tp53 | Rat | acetylsalicylic acid | multiple interactions | ISO | RGD:70502 | 6480464 | Aspirin inhibits the reaction [sodium bichromate results in increased expression of TP53 protein] | CTD | PMID:10942736 |
Tp53 | Rat | acetylsalicylic acid | increases expression | ISO | RGD:11440 | 6480464 | Aspirin results in increased expression of TRP53 protein | CTD | PMID:16880202 |
Tp53 | Rat | acetylsalicylic acid | increases expression | ISO | RGD:70502 | 6480464 | Aspirin results in increased expression of TP53 protein | CTD | PMID:12535653 |
Tp53 | Rat | aconitine | increases expression | EXP | | 6480464 | Aconitine results in increased expression of TP53 protein | CTD | PMID:24840785 |
Tp53 | Rat | acridine orange | multiple interactions | ISO | RGD:70502 | 6480464 | Acridine Orange results in increased stability of and results in increased activity of TP53 protein | CTD | PMID:16177561 |
Tp53 | Rat | acridine orange free base | multiple interactions | ISO | RGD:70502 | 6480464 | Acridine Orange results in increased stability of and results in increased activity of TP53 protein | CTD | PMID:16177561 |
Tp53 | Rat | acrolein | affects metabolic processing | ISO | RGD:70502 | 6480464 | Acrolein affects the metabolism of TP53 protein | CTD | PMID:12807757 |
Tp53 | Rat | acrolein | increases expression | ISO | RGD:70502 | 6480464 | Acrolein results in increased expression of TP53 protein | CTD | PMID:34958888 |
Tp53 | Rat | acrolein | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Acrolein | CTD | PMID:29964147 |
Tp53 | Rat | acrolein | multiple interactions | EXP | | 6480464 | [ferric oxide analog co-treated with Acrolein] results in increased expression of TP53 protein | CTD | PMID:24847785 |
Tp53 | Rat | acrolein | increases mutagenesis | ISO | RGD:70502 | 6480464 | Acrolein results in increased mutagenesis of TP53 gene | CTD | PMID:17030796 |
Tp53 | Rat | acrolein | decreases activity | ISO | RGD:70502 | 6480464 | Acrolein results in decreased activity of TP53 protein | CTD | PMID:12807757|PMID:16753831 |
Tp53 | Rat | acrolein | affects binding | ISO | RGD:70502 | 6480464 | Acrolein binds to TP53 gene | CTD | PMID:17030796 |
Tp53 | Rat | acrolein | multiple interactions | ISO | RGD:70502 | 6480464 | [TP53 protein affects the susceptibility to Acrolein] which affects the localization of CCNB1 protein; Acrolein more ... | CTD | PMID:12807757|PMID:29964147 |
Tp53 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of TP53 mRNA | CTD | PMID:36598108|PMID:37987225 |
Tp53 | Rat | acrylamide | multiple interactions | EXP | | 6480464 | naringin inhibits the reaction [Acrylamide results in increased expression of TP53 mRNA]; Selenium inhibits the more ... | CTD | PMID:36598108|PMID:37987225 |
Tp53 | Rat | acrylamide | increases expression | ISO | RGD:11440 | 6480464 | Acrylamide results in increased expression of TRP53 mRNA; Acrylamide results in increased expression of TRP53 more ... | CTD | PMID:25531190|PMID:28067054|PMID:34906654 |
Tp53 | Rat | acrylamide | multiple interactions | ISO | RGD:11440 | 6480464 | ATF3 protein promotes the reaction [Acrylamide results in increased expression of TRP53 protein] | CTD | PMID:25531190 |
Tp53 | Rat | acrylamide | multiple interactions | ISO | RGD:70502 | 6480464 | Acrylamide results in increased phosphorylation of and results in increased expression of TP53 protein | CTD | PMID:19426797 |
Tp53 | Rat | acrylamide | increases expression | ISO | RGD:70502 | 6480464 | Acrylamide results in increased expression of TP53 protein modified form | CTD | PMID:20734998 |
Tp53 | Rat | acrylamide | increases mutagenesis | ISO | RGD:70502 | 6480464 | Acrylamide results in increased mutagenesis of TP53 gene | CTD | PMID:15240786 |
Tp53 | Rat | acrylonitrile | increases expression | ISO | RGD:70502 | 6480464 | Acrylonitrile results in increased expression of TP53 protein | CTD | PMID:33132245 |
Tp53 | Rat | actinomycin D | multiple interactions | ISO | RGD:70502 | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of and results in increased secretion more ... | CTD | PMID:10531375|PMID:12807743|PMID:12927789|PMID:16024796|PMID:23968587|PMID:38460933 |
Tp53 | Rat | actinomycin D | multiple interactions | ISO | RGD:70502 | 150537096 | Actinomycin D inhibits the reaction [Sunitinib increases expression of TP53 mRNA and protein in breast more ... | RGD | |
Tp53 | Rat | actinomycin D | increases activity | ISO | RGD:70502 | 6480464 | Dactinomycin results in increased activity of TP53 protein | CTD | PMID:12869419|PMID:20655369 |
Tp53 | Rat | actinomycin D | increases expression | ISO | RGD:70502 | 6480464 | Dactinomycin results in increased expression of TP53 protein; Dactinomycin results in increased expression of TP53 more ... | CTD | PMID:12927789|PMID:17581298 |
Tp53 | Rat | adavosertib | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in increased susceptibility to adavosertib | CTD | PMID:25125259 |
Tp53 | Rat | adavosertib | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in increased susceptibility to adavosertib | CTD | PMID:25125259 |
Tp53 | Rat | adefovir pivoxil | affects activity | ISO | RGD:70502 | 6480464 | adefovir dipivoxil affects the activity of TP53 protein | CTD | PMID:25596134|PMID:35435491 |
Tp53 | Rat | aflatoxin B1 | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Aflatoxin B1 | CTD | PMID:24380836 |
Tp53 | Rat | aflatoxin B1 | affects activity | ISO | RGD:70502 | 6480464 | Aflatoxin B1 metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | aflatoxin B1 | increases phosphorylation | ISO | RGD:70502 | 6480464 | Aflatoxin B1 results in increased phosphorylation of TP53 protein | CTD | PMID:32106047|PMID:33984424 |
Tp53 | Rat | aflatoxin B1 | increases methylation | ISO | RGD:70502 | 6480464 | Aflatoxin B1 results in increased methylation of TP53 gene | CTD | PMID:28458013 |
Tp53 | Rat | aflatoxin B1 | decreases expression | ISO | RGD:70502 | 6480464 | Aflatoxin B1 results in decreased expression of TP53 mRNA | CTD | PMID:28943387 |
Tp53 | Rat | aflatoxin B1 | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression more ... | CTD | PMID:28181396 |
Tp53 | Rat | aflatoxin B1 | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Aflatoxin B1 | CTD | PMID:28882572 |
Tp53 | Rat | aflatoxin B1 | increases expression | ISO | RGD:70502 | 6480464 | Aflatoxin B1 results in increased expression of TP53 mRNA; Aflatoxin B1 results in increased expression more ... | CTD | PMID:22100608|PMID:30668976|PMID:31542801|PMID:34089297 |
Tp53 | Rat | aflatoxin B1 | multiple interactions | ISO | RGD:70502 | 6480464 | [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of TP53 more ... | CTD | PMID:20655369|PMID:22100608|PMID:28882572|PMID:30668976 |
Tp53 | Rat | aflatoxin B1 | increases activity | ISO | RGD:70502 | 6480464 | Aflatoxin B1 results in increased activity of TP53 protein | CTD | PMID:20655369 |
Tp53 | Rat | aflatoxin B1 | increases mutagenesis | ISO | RGD:70502 | 6480464 | Aflatoxin B1 results in increased mutagenesis of TP53 gene | CTD | PMID:12619106|PMID:15946497 |
Tp53 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of TP53 mRNA; Aflatoxin B1 results in increased expression more ... | CTD | PMID:28181396|PMID:28442411|PMID:32418920|PMID:9163691 |
Tp53 | Rat | aflatoxin B1 | affects expression | ISO | RGD:70502 | 6480464 | Aflatoxin B1 affects the expression of TP53 protein | CTD | PMID:20106945 |
Tp53 | Rat | aflatoxin B1 | increases expression | ISO | RGD:11440 | 6480464 | Aflatoxin B1 results in increased expression of TRP53 mRNA; Aflatoxin B1 results in increased expression more ... | CTD | PMID:28789997|PMID:29274131|PMID:30126036|PMID:9667752 |
Tp53 | Rat | Aflatoxin G1 | increases expression | ISO | RGD:70502 | 6480464 | aflatoxin G1 results in increased expression of TP53 protein modified form | CTD | PMID:23907605 |
Tp53 | Rat | Aflatoxin G1 | increases activity | ISO | RGD:70502 | 6480464 | aflatoxin G1 results in increased activity of TP53 protein | CTD | PMID:23907605 |
Tp53 | Rat | Aflatoxin G1 | multiple interactions | ISO | RGD:70502 | 6480464 | Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of TP53 protein modified form]; more ... | CTD | PMID:23907605 |
Tp53 | Rat | AICA ribonucleotide | multiple interactions | ISO | RGD:70502 | 6480464 | [Resveratrol co-treated with AICA ribonucleotide] inhibits the reaction [Glucose results in increased expression of TP53 more ... | CTD | PMID:26188290|PMID:33070465 |
Tp53 | Rat | AICA ribonucleotide | increases phosphorylation | ISO | RGD:70502 | 6480464 | AICA ribonucleotide results in increased phosphorylation of TP53 protein | CTD | PMID:33070465 |
Tp53 | Rat | alantolactone | increases expression | ISO | RGD:70502 | 6480464 | alantolactone results in increased expression of TP53 protein | CTD | PMID:22721982 |
Tp53 | Rat | albendazole | affects activity | ISO | RGD:70502 | 6480464 | Albendazole affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | albendazole S-oxide | affects activity | ISO | RGD:70502 | 6480464 | albendazole sulfoxide affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | albuterol | increases expression | ISO | RGD:70502 | 6480464 | Albuterol results in increased expression of TP53 | CTD | PMID:11802967 |
Tp53 | Rat | aldehydo-D-glucose | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytic Acid inhibits the reaction [Glucose results in increased expression of more ... | CTD | PMID:20068143|PMID:21548882|PMID:24218232|PMID:24451382|PMID:26188290|PMID:27049278|PMID:33962019|PMID:35264022|PMID:38000455 |
Tp53 | Rat | aldehydo-D-glucose | increases expression | EXP | | 6480464 | Glucose results in increased expression of TP53 protein | CTD | PMID:38483099 |
Tp53 | Rat | aldehydo-D-glucose | multiple interactions | ISO | RGD:11440 | 6480464 | [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of TRP53 protein; [Oxygen deficiency more ... | CTD | PMID:28675767 |
Tp53 | Rat | aldehydo-D-glucose | increases expression | ISO | RGD:70502 | 6480464 | Glucose results in increased expression of TP53 mRNA; Glucose results in increased expression of TP53 more ... | CTD | PMID:26188290|PMID:27049278|PMID:35264022|PMID:38000455|PMID:38483099 |
Tp53 | Rat | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in more ... | CTD | PMID:23451161|PMID:25997894 |
Tp53 | Rat | aldehydo-D-glucose | increases acetylation | ISO | RGD:70502 | 6480464 | Glucose results in increased acetylation of TP53 protein | CTD | PMID:20068143 |
Tp53 | Rat | aldehydo-D-glucose | affects localization | ISO | RGD:70502 | 6480464 | Glucose affects the localization of TP53 protein | CTD | PMID:24218232 |
Tp53 | Rat | all-cis-docosa-7,10,13,16-tetraenoic acid | multiple interactions | ISO | RGD:11440 | 6480464 | [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance more ... | CTD | PMID:30258081 |
Tp53 | Rat | all-trans-retinoic acid | decreases expression | ISO | RGD:11440 | 6480464 | Tretinoin results in decreased expression of TRP53 mRNA | CTD | PMID:16604517 |
Tp53 | Rat | all-trans-retinoic acid | increases expression | ISO | RGD:11440 | 6480464 | Tretinoin results in increased expression of TRP53 protein | CTD | PMID:33823233 |
Tp53 | Rat | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of TP53 protein | CTD | PMID:17962954 |
Tp53 | Rat | all-trans-retinoic acid | increases expression | ISO | RGD:70502 | 6480464 | Tretinoin results in increased expression of TP53 mRNA; Tretinoin results in increased expression of TP53 more ... | CTD | PMID:15254726|PMID:16054129|PMID:16473924|PMID:16752155|PMID:16935849|PMID:20507312 |
Tp53 | Rat | all-trans-retinoic acid | increases activity | ISO | RGD:70502 | 6480464 | Tretinoin results in increased activity of TP53 protein | CTD | PMID:15674351 |
Tp53 | Rat | all-trans-retinoic acid | decreases expression | ISO | RGD:70502 | 6480464 | Tretinoin results in decreased expression of TP53 mRNA; Tretinoin results in decreased expression of TP53 more ... | CTD | PMID:16461808|PMID:34742744 |
Tp53 | Rat | all-trans-retinoic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [Tretinoin co-treated with zoledronic acid] results in decreased expression of TP53 protein; [Tretinoin results in more ... | CTD | PMID:16740359|PMID:17293044|PMID:17327230|PMID:20349282|PMID:21532991|PMID:21548882 |
Tp53 | Rat | all-trans-retinoic acid | affects expression | ISO | RGD:70502 | 6480464 | Tretinoin affects the expression of TP53 | CTD | PMID:16720286 |
Tp53 | Rat | allethrin | increases expression | EXP | | 6480464 | Allethrins results in increased expression of TP53 mRNA | CTD | PMID:25072698 |
Tp53 | Rat | allethrin | decreases expression | EXP | | 6480464 | Allethrins results in decreased expression of TP53 mRNA | CTD | PMID:23595975 |
Tp53 | Rat | allethrin | affects expression | EXP | | 6480464 | Allethrins affects the expression of TP53 protein | CTD | PMID:22356257 |
Tp53 | Rat | alliin | multiple interactions | ISO | RGD:70502 | 6480464 | alliin promotes the reaction [FGF2 protein results in increased expression of TP53 protein] | CTD | PMID:16351512 |
Tp53 | Rat | allose | increases expression | ISO | RGD:70502 | 6480464 | allose results in increased expression of TP53 mRNA; allose results in increased expression of TP53 more ... | CTD | PMID:18930000 |
Tp53 | Rat | allose | multiple interactions | ISO | RGD:70502 | 6480464 | Fluorouracil promotes the reaction [allose results in increased expression of TP53 protein] | CTD | PMID:18930000 |
Tp53 | Rat | Aloe emodin | increases expression | ISO | RGD:70502 | 6480464 | aloe emodin results in increased expression of TP53 protein | CTD | PMID:19928967 |
Tp53 | Rat | alpha-D-galactose | increases expression | ISO | RGD:70502 | 6480464 | Galactose results in increased expression of TP53 protein | CTD | PMID:23036742|PMID:29426000 |
Tp53 | Rat | alpha-D-galactose | increases expression | EXP | | 6480464 | Galactose results in increased expression of TP53 protein | CTD | PMID:39265715 |
Tp53 | Rat | alpha-D-galactose | multiple interactions | EXP | | 6480464 | [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in more ... | CTD | PMID:25997894|PMID:39265715 |
Tp53 | Rat | alpha-D-galactose | multiple interactions | ISO | RGD:70502 | 6480464 | Phycocyanin inhibits the reaction [Galactose results in increased expression of TP53 protein] | CTD | PMID:23036742 |
Tp53 | Rat | alpha-hexachlorocyclohexane | increases expression | EXP | | 6480464 | alpha-hexachlorocyclohexane results in increased expression of TP53 mRNA | CTD | PMID:16940010 |
Tp53 | Rat | alpha-hexachlorocyclohexane | affects expression | EXP | | 6480464 | alpha-hexachlorocyclohexane affects the expression of TRP53 mRNA | CTD | PMID:16940010 |
Tp53 | Rat | alpha-hexachlorocyclohexane | decreases expression | EXP | | 6480464 | alpha-hexachlorocyclohexane results in decreased expression of TP53 mRNA | CTD | PMID:16940010 |
Tp53 | Rat | alpha-mangostin | increases expression | ISO | RGD:70502 | 6480464 | mangostin results in increased expression of TP53 protein | CTD | PMID:24480042 |
Tp53 | Rat | alpha-mangostin | multiple interactions | ISO | RGD:70502 | 6480464 | mangostin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TP53 mRNA] | CTD | PMID:26357513 |
Tp53 | Rat | alpha-naphthoflavone | multiple interactions | EXP | | 6480464 | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [leptomycin B results in increased expression of more ... | CTD | PMID:15459018 |
Tp53 | Rat | alpha-naphthoflavone | multiple interactions | ISO | RGD:70502 | 6480464 | alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene] which results in more ... | CTD | PMID:32553695 |
Tp53 | Rat | alpha-naphthoflavone | increases expression | ISO | RGD:70502 | 6480464 | alpha-naphthoflavone results in increased expression of TP53 protein | CTD | PMID:29274324 |
Tp53 | Rat | alpha-naphthoflavone | multiple interactions | ISO | RGD:11440 | 6480464 | alpha-naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased phosphorylation of TRP53 protein]; alpha-naphthoflavone inhibits the more ... | CTD | PMID:35908932|PMID:9006915 |
Tp53 | Rat | alpha-phellandrene | increases phosphorylation | ISO | RGD:11440 | 6480464 | alpha phellandrene results in increased phosphorylation of TRP53 protein | CTD | PMID:24861204 |
Tp53 | Rat | alpha-phellandrene | affects localization | ISO | RGD:70502 | 6480464 | alpha phellandrene affects the localization of TP53 protein | CTD | PMID:25649747 |
Tp53 | Rat | alpha-phellandrene | decreases expression | ISO | RGD:11440 | 6480464 | alpha phellandrene results in decreased expression of TRP53 protein | CTD | PMID:24861204 |
Tp53 | Rat | alpha-phellandrene | increases expression | ISO | RGD:11440 | 6480464 | alpha phellandrene results in increased expression of TRP53 protein modified form | CTD | PMID:24861204 |
Tp53 | Rat | alsterpaullone | affects localization | ISO | RGD:70502 | 6480464 | alsterpaullone affects the localization of TP53 protein | CTD | PMID:16055726 |
Tp53 | Rat | alsterpaullone | multiple interactions | ISO | RGD:70502 | 6480464 | alsterpaullone results in decreased degradation of and results in increased expression of TP53 protein | CTD | PMID:16055726 |
Tp53 | Rat | alternariol | increases expression | ISO | RGD:70502 | 6480464 | alternariol results in increased expression of TP53 protein | CTD | PMID:22542754 |
Tp53 | Rat | aluminium oxide | increases expression | ISO | RGD:70502 | 6480464 | Aluminum Oxide analog results in increased expression of TP53 mRNA | CTD | PMID:23132795 |
Tp53 | Rat | alvocidib | decreases expression | ISO | RGD:70502 | 6480464 | alvocidib results in decreased expression of TP53 protein | CTD | PMID:9808574 |
Tp53 | Rat | alvocidib | multiple interactions | ISO | RGD:70502 | 6480464 | [docetaxel co-treated with alvocidib] results in increased expression of TP53 protein | CTD | PMID:15297405 |
Tp53 | Rat | alvocidib | increases expression | ISO | RGD:70502 | 6480464 | [alvocidib results in increased expression of TP53 protein] which results in increased expression of CDKN1B more ... | CTD | PMID:10537362|PMID:12589031|PMID:15180955 |
Tp53 | Rat | amifostine | multiple interactions | ISO | RGD:70502 | 6480464 | [Amifostine co-treated with TP53] results in increased expression of MYC mRNA; olomoucine inhibits the reaction more ... | CTD | PMID:14555708|PMID:16628227 |
Tp53 | Rat | amifostine | increases expression | ISO | RGD:70502 | 6480464 | Amifostine results in increased expression of TP53 protein | CTD | PMID:12618886 |
Tp53 | Rat | amifostine | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 affects the susceptibility to Amifostine | CTD | PMID:12618886 |
Tp53 | Rat | amifostine | increases activity | ISO | RGD:70502 | 6480464 | Amifostine results in increased activity of TP53 protein | CTD | PMID:16628227 |
Tp53 | Rat | amiodarone | decreases expression | ISO | RGD:70502 | 6480464 | Amiodarone results in decreased expression of TP53 mRNA | CTD | PMID:35641671 |
Tp53 | Rat | ammonium chloride | increases expression | EXP | | 6480464 | Ammonium Chloride results in increased expression of TP53 protein | CTD | PMID:16483693 |
Tp53 | Rat | ammonium chloride | increases expression | ISO | RGD:11440 | 6480464 | Ammonium Chloride results in increased expression of TRP53 mRNA | CTD | PMID:31310755 |
Tp53 | Rat | ammonium chloride | multiple interactions | ISO | RGD:70502 | 6480464 | Ammonium Chloride affects the expression of and affects the phosphorylation of TP53 protein; NR1I2 protein more ... | CTD | PMID:29908302 |
Tp53 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of TP53 mRNA | CTD | PMID:16483693 |
Tp53 | Rat | amodiaquine | increases activity | ISO | RGD:70502 | 6480464 | Amodiaquine results in increased activity of TP53 protein | CTD | PMID:12082016 |
Tp53 | Rat | amodiaquine | affects expression | ISO | RGD:70502 | 6480464 | Amodiaquine affects the expression of TP53 protein | CTD | PMID:24113242 |
Tp53 | Rat | amosite asbestos | affects localization | ISO | RGD:70502 | 6480464 | Asbestos, Amosite affects the localization of TP53 protein | CTD | PMID:16357363 |
Tp53 | Rat | amosite asbestos | multiple interactions | ISO | RGD:11440 | 6480464 | Asbestos, Amosite results in increased susceptibility to [NF2 protein mutant form co-treated with CDKN2A protein more ... | CTD | PMID:37441092 |
Tp53 | Rat | amosite asbestos | multiple interactions | EXP | | 6480464 | Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 protein] | CTD | PMID:16357363 |
Tp53 | Rat | amosite asbestos | increases expression | EXP | | 6480464 | Asbestos, Amosite results in increased expression of TP53 protein | CTD | PMID:16357363 |
Tp53 | Rat | amosite asbestos | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Asbestos, Amosite | CTD | PMID:16357363 |
Tp53 | Rat | amosite asbestos | multiple interactions | ISO | RGD:70502 | 6480464 | Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]; Phytic Acid more ... | CTD | PMID:16357363 |
Tp53 | Rat | amosite asbestos | increases expression | ISO | RGD:70502 | 6480464 | Asbestos, Amosite results in increased expression of TP53 mRNA; Asbestos, Amosite results in increased expression more ... | CTD | PMID:16357363 |
Tp53 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of TP53 mRNA | CTD | PMID:30779732 |
Tp53 | Rat | amphetamine | increases expression | ISO | RGD:11440 | 6480464 | Amphetamine results in increased expression of TRP53 mRNA; Amphetamine results in increased expression of TRP53 more ... | CTD | PMID:15731293 |
Tp53 | Rat | amphibole asbestos | multiple interactions | ISO | RGD:70502 | 6480464 | Asbestos, Amphibole results in increased phosphorylation of and results in increased stability of TP53 protein | CTD | PMID:20705543 |
Tp53 | Rat | amphibole asbestos | affects expression | ISO | RGD:70502 | 6480464 | Asbestos, Amphibole affects the expression of TP53 protein | CTD | PMID:20855422 |
Tp53 | Rat | amsacrine | increases activity | ISO | RGD:70502 | 6480464 | Amsacrine analog results in increased activity of TP53 protein | CTD | PMID:12082016 |
Tp53 | Rat | amsacrine | increases glutathionylation | ISO | RGD:70502 | 6480464 | Amsacrine results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | amsacrine | multiple interactions | ISO | RGD:70502 | 6480464 | Amsacrine results in increased stability of and results in increased activity of TP53 protein | CTD | PMID:16177561 |
Tp53 | Rat | amsacrine | increases expression | ISO | RGD:70502 | 6480464 | Amsacrine results in increased expression of TP53 protein | CTD | PMID:11774253 |
Tp53 | Rat | andrographolide | multiple interactions | ISO | RGD:70502 | 6480464 | andrographolide results in increased expression of and results in increased phosphorylation of TP53 protein; Fluorouracil more ... | CTD | PMID:18619950|PMID:19097688 |
Tp53 | Rat | andrographolide | increases expression | ISO | RGD:70502 | 6480464 | andrographolide results in increased expression of TP53 | CTD | PMID:19097688 |
Tp53 | Rat | anthra[1,9-cd]pyrazol-6(2H)-one | multiple interactions | ISO | RGD:11440 | 6480464 | pyrazolanthrone promotes the reaction [TRP53 gene mutant form results in decreased susceptibility to sodium arsenite] | CTD | PMID:16166651 |
Tp53 | Rat | anthra[1,9-cd]pyrazol-6(2H)-one | multiple interactions | EXP | | 6480464 | pyrazolanthrone inhibits the reaction [Colistin results in increased expression of TP53 protein] | CTD | PMID:28842171 |
Tp53 | Rat | anthra[1,9-cd]pyrazol-6(2H)-one | increases phosphorylation | ISO | RGD:70502 | 6480464 | pyrazolanthrone results in increased phosphorylation of TP53 protein | CTD | PMID:25305377 |
Tp53 | Rat | anthra[1,9-cd]pyrazol-6(2H)-one | increases expression | ISO | RGD:70502 | 6480464 | pyrazolanthrone results in increased expression of TP53 protein; pyrazolanthrone results in increased expression of TP53 more ... | CTD | PMID:15034932|PMID:16061660|PMID:26630137 |
Tp53 | Rat | anthra[1,9-cd]pyrazol-6(2H)-one | decreases expression | ISO | RGD:70502 | 6480464 | pyrazolanthrone results in decreased expression of TP53 protein | CTD | PMID:16450001 |
Tp53 | Rat | anthra[1,9-cd]pyrazol-6(2H)-one | multiple interactions | ISO | RGD:70502 | 6480464 | [sodium arsenite co-treated with pyrazolanthrone] promotes the reaction [HSPA9 protein binds to TP53 protein modified more ... | CTD | PMID:15034932|PMID:17292493|PMID:20191265|PMID:22706169|PMID:25939952|PMID:26630137|PMID:31734849|PMID:32238696|PMID:36319700 |
Tp53 | Rat | anthra[1,9-cd]pyrazol-6(2H)-one | increases phosphorylation | EXP | | 6480464 | pyrazolanthrone results in increased phosphorylation of TP53 protein | CTD | PMID:16046226 |
Tp53 | Rat | antimony trichloride | increases expression | ISO | RGD:11440 | 6480464 | antimony trichloride results in increased expression of TRP53 mRNA; antimony trichloride results in increased expression more ... | CTD | PMID:34091186 |
Tp53 | Rat | antimony trichloride | multiple interactions | ISO | RGD:11440 | 6480464 | antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of TRP53 protein]; arsenic more ... | CTD | PMID:34091186 |
Tp53 | Rat | antimycin A | increases acetylation | ISO | RGD:11440 | 6480464 | Antimycin A results in increased acetylation of TRP53 protein | CTD | PMID:24040102 |
Tp53 | Rat | antimycin A | multiple interactions | ISO | RGD:11440 | 6480464 | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide promotes the reaction [Antimycin A results in increased acetylation of TRP53 protein]; Resveratrol inhibits more ... | CTD | PMID:24040102 |
Tp53 | Rat | antimycin A | increases response to substance | ISO | RGD:70502 | 6480464 | TRP53 protein results in increased susceptibility to Antimycin A | CTD | PMID:24040102 |
Tp53 | Rat | aphidicolin | multiple interactions | ISO | RGD:11440 | 6480464 | [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased more ... | CTD | PMID:22003191 |
Tp53 | Rat | apigenin | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the reaction [Apigenin results in increased expression of CDKN1A protein] | CTD | PMID:11790449 |
Tp53 | Rat | apigenin | affects activity | ISO | RGD:70502 | 6480464 | Apigenin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | apigenin | increases expression | ISO | RGD:70502 | 6480464 | Apigenin results in increased expression of TP53 protein | CTD | PMID:16023288 |
Tp53 | Rat | apocynin | multiple interactions | EXP | | 6480464 | acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 more ... | CTD | PMID:22431579 |
Tp53 | Rat | arachidonic acid | multiple interactions | ISO | RGD:11440 | 6480464 | [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance more ... | CTD | PMID:30258081 |
Tp53 | Rat | arachidonic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [TP53 protein results in increased expression of ALOX12B mRNA] which results in increased metabolism of more ... | CTD | PMID:30258081 |
Tp53 | Rat | arachidonyl-2'-chloroethylamide | multiple interactions | ISO | RGD:11440 | 6480464 | arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased phosphorylation of TRP53 protein] | CTD | PMID:31256211 |
Tp53 | Rat | arecoline | increases expression | ISO | RGD:70502 | 6480464 | Arecoline results in increased expression of TP53 protein | CTD | PMID:22108589 |
Tp53 | Rat | arecoline | multiple interactions | ISO | RGD:70502 | 6480464 | [[Arecoline results in decreased expression of CDC25C] co-treated with [Arecoline results in increased expression of more ... | CTD | PMID:22108589 |
Tp53 | Rat | arecoline hydrobromide | increases phosphorylation | EXP | | 6480464 | arecoline hydrobromide results in increased phosphorylation of TP53 protein | CTD | PMID:17997002 |
Tp53 | Rat | Arg-Gly-Asp | multiple interactions | ISO | RGD:70502 | 6480464 | arginyl-glycyl-aspartic acid inhibits the reaction [Resveratrol results in increased phosphorylation of TP53 protein] | CTD | PMID:16790523 |
Tp53 | Rat | aristolochic acid A | increases expression | ISO | RGD:70502 | 6480464 | aristolochic acid I results in increased expression of TP53 mRNA | CTD | PMID:33212167 |
Tp53 | Rat | aristolochic acid A | multiple interactions | ISO | RGD:70502 | 6480464 | aristolochic acid I results in increased expression of and results in increased phosphorylation of TP53 more ... | CTD | PMID:33938965 |
Tp53 | Rat | aristolochic acid A | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to aristolochic acid I | CTD | PMID:31602497 |
Tp53 | Rat | aristolochic acid A | increases expression | ISO | RGD:11440 | 6480464 | aristolochic acid I results in increased expression of TRP53 protein | CTD | PMID:31602497 |
Tp53 | Rat | aristolochic acid A | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 protein affects the reaction [aristolochic acid I results in increased expression of H2AX protein]; more ... | CTD | PMID:31602497 |
Tp53 | Rat | aristolochic acids | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased phosphorylation of TP53 protein] | CTD | PMID:24792323 |
Tp53 | Rat | aristolochic acids | increases phosphorylation | ISO | RGD:70502 | 6480464 | Aristolochic Acids results in increased phosphorylation of TP53 protein | CTD | PMID:24792323 |
Tp53 | Rat | Aroclor 1254 | increases expression | ISO | RGD:11440 | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of TRP53 mRNA | CTD | PMID:25113976 |
Tp53 | Rat | Aroclor 1254 | increases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of TP53 protein | CTD | PMID:35822628 |
Tp53 | Rat | Aroclor 1254 | multiple interactions | EXP | | 6480464 | 2-(1',2',3',4'-tetrahydroxybutyl)thiazolidine-4-carboxylic acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of TP53 protein] | CTD | PMID:35822628 |
Tp53 | Rat | arsane | affects expression | ISO | RGD:70502 | 6480464 | Arsenic affects the expression of TP53 mRNA; Arsenic affects the expression of TP53 protein | CTD | PMID:17450239|PMID:18414638 |
Tp53 | Rat | arsane | multiple interactions | ISO | RGD:70502 | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TP53 more ... | CTD | PMID:34998823|PMID:39836092 |
Tp53 | Rat | arsane | multiple interactions | ISO | RGD:11440 | 6480464 | [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [[Sodium Fluoride results in more ... | CTD | PMID:35714946 |
Tp53 | Rat | arsane | multiple interactions | EXP | | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TP53 more ... | CTD | PMID:31542844|PMID:32402895 |
Tp53 | Rat | arsane | increases mutagenesis | ISO | RGD:70502 | 6480464 | Arsenic results in increased mutagenesis of TP53 exon; Arsenic results in increased mutagenesis of TP53 more ... | CTD | PMID:15967209|PMID:17450239|PMID:21756780|PMID:26772154|PMID:34998823 |
Tp53 | Rat | arsane | affects localization | ISO | RGD:11440 | 6480464 | Arsenic affects the localization of TRP53 protein | CTD | PMID:27289040 |
Tp53 | Rat | arsane | decreases phosphorylation | ISO | RGD:70502 | 6480464 | Arsenic results in decreased phosphorylation of TP53 protein | CTD | PMID:24473091 |
Tp53 | Rat | arsane | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 polymorphism affects the susceptibility to Arsenic | CTD | PMID:21982800 |
Tp53 | Rat | arsane | increases methylation | ISO | RGD:70502 | 6480464 | Arsenic results in increased methylation of TP53 promoter | CTD | PMID:16251483|PMID:21756780 |
Tp53 | Rat | arsane | decreases expression | ISO | RGD:70502 | 6480464 | Arsenic results in decreased expression of TP53 mRNA; Arsenic results in decreased expression of TP53 more ... | CTD | PMID:19945496|PMID:28785074 |
Tp53 | Rat | arsane | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in increased susceptibility to Arsenic; TP53 gene polymorphism results in more ... | CTD | PMID:16930632|PMID:23643801 |
Tp53 | Rat | arsane | increases expression | ISO | RGD:70502 | 6480464 | Arsenic results in increased expression of TP53 mRNA; Arsenic results in increased expression of TP53 more ... | CTD | PMID:12899209|PMID:23174854|PMID:27122327|PMID:34998823 |
Tp53 | Rat | arsane | decreases methylation | ISO | RGD:70502 | 6480464 | Arsenic results in decreased methylation of TP53 exon | CTD | PMID:21756780 |
Tp53 | Rat | arsenic acid | increases expression | ISO | RGD:11440 | 6480464 | arsenic acid results in increased expression of TRP53 mRNA | CTD | PMID:8946558 |
Tp53 | Rat | arsenic atom | affects expression | ISO | RGD:70502 | 6480464 | Arsenic affects the expression of TP53 mRNA; Arsenic affects the expression of TP53 protein | CTD | PMID:17450239|PMID:18414638 |
Tp53 | Rat | arsenic atom | multiple interactions | ISO | RGD:70502 | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TP53 more ... | CTD | PMID:34998823|PMID:39836092 |
Tp53 | Rat | arsenic atom | multiple interactions | ISO | RGD:11440 | 6480464 | [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [[Sodium Fluoride results in more ... | CTD | PMID:35714946 |
Tp53 | Rat | arsenic atom | multiple interactions | EXP | | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TP53 more ... | CTD | PMID:31542844|PMID:32402895 |
Tp53 | Rat | arsenic atom | increases mutagenesis | ISO | RGD:70502 | 6480464 | Arsenic results in increased mutagenesis of TP53 exon; Arsenic results in increased mutagenesis of TP53 more ... | CTD | PMID:15967209|PMID:17450239|PMID:21756780|PMID:26772154|PMID:34998823 |
Tp53 | Rat | arsenic atom | affects localization | ISO | RGD:11440 | 6480464 | Arsenic affects the localization of TRP53 protein | CTD | PMID:27289040 |
Tp53 | Rat | arsenic atom | decreases phosphorylation | ISO | RGD:70502 | 6480464 | Arsenic results in decreased phosphorylation of TP53 protein | CTD | PMID:24473091 |
Tp53 | Rat | arsenic atom | increases methylation | ISO | RGD:70502 | 6480464 | Arsenic results in increased methylation of TP53 promoter | CTD | PMID:16251483|PMID:21756780 |
Tp53 | Rat | arsenic atom | decreases methylation | ISO | RGD:70502 | 6480464 | Arsenic results in decreased methylation of TP53 exon | CTD | PMID:21756780 |
Tp53 | Rat | arsenic atom | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 polymorphism affects the susceptibility to Arsenic | CTD | PMID:21982800 |
Tp53 | Rat | arsenic atom | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in increased susceptibility to Arsenic; TP53 gene polymorphism results in more ... | CTD | PMID:16930632|PMID:23643801 |
Tp53 | Rat | arsenic atom | increases expression | ISO | RGD:70502 | 6480464 | Arsenic results in increased expression of TP53 mRNA; Arsenic results in increased expression of TP53 more ... | CTD | PMID:12899209|PMID:23174854|PMID:27122327|PMID:34998823 |
Tp53 | Rat | arsenic atom | decreases expression | ISO | RGD:70502 | 6480464 | Arsenic results in decreased expression of TP53 mRNA; Arsenic results in decreased expression of TP53 more ... | CTD | PMID:19945496|PMID:28785074 |
Tp53 | Rat | arsenic trichloride | increases phosphorylation | ISO | RGD:11440 | 6480464 | arsenic trichloride results in increased phosphorylation of TRP53 protein | CTD | PMID:16283526 |
Tp53 | Rat | arsenic trichloride | multiple interactions | ISO | RGD:11440 | 6480464 | arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of TRP53 mRNA]; arsenic more ... | CTD | PMID:34091186 |
Tp53 | Rat | arsenite(3-) | increases expression | ISO | RGD:70502 | 6480464 | arsenite results in increased expression of TP53 mRNA; arsenite results in increased expression of TP53 more ... | CTD | PMID:12126965|PMID:22260869|PMID:25281835|PMID:30177839 |
Tp53 | Rat | arsenite(3-) | increases activity | ISO | RGD:70502 | 6480464 | arsenite results in increased activity of TP53 protein | CTD | PMID:30177839 |
Tp53 | Rat | arsenite(3-) | decreases degradation | ISO | RGD:11440 | 6480464 | arsenite results in decreased degradation of TRP53 protein | CTD | PMID:23396362 |
Tp53 | Rat | arsenite(3-) | decreases phosphorylation | ISO | RGD:70502 | 6480464 | arsenite results in decreased phosphorylation of TP53 protein | CTD | PMID:22447124 |
Tp53 | Rat | arsenite(3-) | multiple interactions | ISO | RGD:11440 | 6480464 | AKT1 protein modified form inhibits the reaction [arsenite results in increased expression of and results more ... | CTD | PMID:16739126|PMID:18929588|PMID:23396362 |
Tp53 | Rat | arsenite(3-) | affects methylation | ISO | RGD:70502 | 6480464 | arsenite affects the methylation of TP53 promoter | CTD | PMID:11489357 |
Tp53 | Rat | arsenite(3-) | multiple interactions | ISO | RGD:70502 | 6480464 | 3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]; [[[arsenite more ... | CTD | PMID:12126965|PMID:20199942|PMID:22260869|PMID:22366412|PMID:22447124|PMID:23968587|PMID:25281835|PMID:30177839|PMID:33097607 |
Tp53 | Rat | arsenous acid | multiple interactions | EXP | | 6480464 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of TP53 protein]; pifithrin inhibits more ... | CTD | PMID:17487067|PMID:23337567|PMID:29130132 |
Tp53 | Rat | arsenous acid | increases expression | ISO | RGD:11440 | 6480464 | Arsenic Trioxide results in increased expression of TRP53 mRNA; Arsenic Trioxide results in increased expression more ... | CTD | PMID:34091186 |
Tp53 | Rat | arsenous acid | affects expression | ISO | RGD:70502 | 6480464 | Arsenic Trioxide affects the expression of TP53 | CTD | PMID:11775218 |
Tp53 | Rat | arsenous acid | multiple interactions | ISO | RGD:70502 | 6480464 | [Arsenic Trioxide co-treated with Curcumin] results in increased expression of TP53 protein; [Arsenic Trioxide co-treated more ... | CTD | PMID:12851490|PMID:15904916|PMID:17064470|PMID:18167198|PMID:20377131|PMID:23851143|PMID:23968587|PMID:24738333|PMID:25574600|PMID:26110921|PMID:27430728|PMID:29266867|PMID:29274334|PMID:29944906|PMID:30012499|PMID:31307525|PMID:31734849|PMID:32017938|PMID:34042274|PMID:36352148 |
Tp53 | Rat | arsenous acid | decreases expression | ISO | RGD:70502 | 6480464 | Arsenic Trioxide results in decreased expression of TP53 mRNA; Arsenic Trioxide results in decreased expression more ... | CTD | PMID:21454520|PMID:27825931|PMID:29164574|PMID:36442592 |
Tp53 | Rat | arsenous acid | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 affects the susceptibility to Arsenic Trioxide; TP53 protein affects the susceptibility to Arsenic Trioxide | CTD | PMID:12851490|PMID:29535630|PMID:35030298 |
Tp53 | Rat | arsenous acid | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein mutant form results in decreased susceptibility to Arsenic Trioxide | CTD | PMID:21454520|PMID:24884809 |
Tp53 | Rat | arsenous acid | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of TP53 mRNA; Arsenic Trioxide results in increased expression more ... | CTD | PMID:21145380|PMID:22801079|PMID:29130132|PMID:31734849 |
Tp53 | Rat | arsenous acid | increases degradation | ISO | RGD:70502 | 6480464 | Arsenic Trioxide results in increased degradation of TP53 protein | CTD | PMID:19457607 |
Tp53 | Rat | arsenous acid | increases activity | EXP | | 6480464 | Arsenic Trioxide results in increased activity of TP53 protein | CTD | PMID:17487067 |
Tp53 | Rat | arsenous acid | increases phosphorylation | ISO | RGD:70502 | 6480464 | Arsenic Trioxide results in increased phosphorylation of TP53 protein | CTD | PMID:29944906|PMID:30472098|PMID:36801614 |
Tp53 | Rat | arsenous acid | multiple interactions | ISO | RGD:11440 | 6480464 | Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in increased more ... | CTD | PMID:21565247|PMID:27638049|PMID:34091186 |
Tp53 | Rat | arsenous acid | increases phosphorylation | ISO | RGD:11440 | 6480464 | Arsenic Trioxide results in increased phosphorylation of TP53 protein | CTD | PMID:27638049 |
Tp53 | Rat | arsenous acid | increases expression | ISO | RGD:70502 | 6480464 | Arsenic Trioxide results in increased expression of TP53 mRNA; Arsenic Trioxide results in increased expression more ... | CTD | PMID:10841286|PMID:10850458|PMID:11146441|PMID:11834893|PMID:12490120|PMID:15352174|PMID:15904916|PMID:15979894|PMID:16467208|PMID:17530438|PMID:19444595|PMID:19769630|PMID:20200477|PMID:20953137|PMID:21454520|PMID:21792014|PMID:23440206|PMID:23851143|PMID:26110921|PMID:27430728|PMID:29274334|PMID:31307525|PMID:31734849|PMID:32017938|PMID:34042274 |
Tp53 | Rat | arsenous acid | increases phosphorylation | EXP | | 6480464 | Arsenic Trioxide results in increased phosphorylation of TP53 protein | CTD | PMID:23337567 |
Tp53 | Rat | artesunate | increases expression | ISO | RGD:70502 | 6480464 | Artesunate results in increased expression of TP53 protein | CTD | PMID:33259807 |
Tp53 | Rat | artesunate | multiple interactions | ISO | RGD:70502 | 6480464 | Artesunate inhibits the reaction [TPT1 protein binds to TP53 protein] | CTD | PMID:33259807 |
Tp53 | Rat | asbestos | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 gene SNP affects the susceptibility to Asbestos | CTD | PMID:23435014 |
Tp53 | Rat | asbestos | increases expression | ISO | RGD:70502 | 6480464 | Asbestos results in increased expression of TP53 protein | CTD | PMID:8049841 |
Tp53 | Rat | asbestos | affects localization | ISO | RGD:70502 | 6480464 | Asbestos affects the localization of TP53 protein | CTD | PMID:25466987 |
Tp53 | Rat | asbestos | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in increased susceptibility to Asbestos | CTD | PMID:15136429 |
Tp53 | Rat | aspartame | increases expression | ISO | RGD:11440 | 6480464 | Aspartame results in increased expression of TRP53; Aspartame results in increased expression of TRP53 mRNA | CTD | PMID:17354619|PMID:32951320 |
Tp53 | Rat | aspartame | multiple interactions | ISO | RGD:11440 | 6480464 | [Fats, Unsaturated co-treated with Aspartame] affects the expression of TRP53 mRNA; [Fats, Unsaturated co-treated with more ... | CTD | PMID:23783067 |
Tp53 | Rat | astaxanthin | multiple interactions | EXP | | 6480464 | astaxanthine inhibits the reaction [Cyclophosphamide results in increased expression of TP53 protein] | CTD | PMID:20038455 |
Tp53 | Rat | astilbin | multiple interactions | ISO | RGD:70502 | 6480464 | astilbin inhibits the reaction [Cisplatin results in increased expression of TP53 protein] | CTD | PMID:29471006 |
Tp53 | Rat | Atipamezole | multiple interactions | EXP | | 6480464 | atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in more ... | CTD | PMID:30597158 |
Tp53 | Rat | atorvastatin calcium | increases expression | ISO | RGD:70502 | 6480464 | Atorvastatin results in increased expression of TP53 protein | CTD | PMID:29630879 |
Tp53 | Rat | atorvastatin calcium | multiple interactions | ISO | RGD:11440 | 6480464 | Atorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the more ... | CTD | PMID:37121058 |
Tp53 | Rat | ATP | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein inhibits the reaction [Deoxyglucose results in decreased abundance of Adenosine Triphosphate] | CTD | PMID:21042727 |
Tp53 | Rat | ATP | increases abundance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in increased abundance of Adenosine Triphosphate | CTD | PMID:33070465 |
Tp53 | Rat | Atranorin | decreases expression | ISO | RGD:70502 | 6480464 | atranorin results in decreased expression of TP53 protein | CTD | PMID:22285236 |
Tp53 | Rat | atrasentan | multiple interactions | EXP | | 6480464 | atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 more ... | CTD | PMID:22431579 |
Tp53 | Rat | atrazine | increases expression | EXP | | 6480464 | Atrazine results in increased expression of TP53 mRNA; Atrazine results in increased expression of TP53 more ... | CTD | PMID:30084861|PMID:9486943 |
Tp53 | Rat | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of TP53 mRNA | CTD | PMID:34663174 |
Tp53 | Rat | atrazine | multiple interactions | ISO | RGD:11440 | 6480464 | Curcumin inhibits the reaction [Atrazine results in increased expression of TP53 mRNA]; Curcumin inhibits the more ... | CTD | PMID:38301994 |
Tp53 | Rat | atrazine | decreases expression | ISO | RGD:11440 | 6480464 | Atrazine results in decreased expression of TRP53 mRNA | CTD | PMID:33463082 |
Tp53 | Rat | atrazine | increases expression | ISO | RGD:11440 | 6480464 | Atrazine results in increased expression of TP53 mRNA; Atrazine results in increased expression of TP53 more ... | CTD | PMID:33485040|PMID:38301994 |
Tp53 | Rat | atrazine | decreases expression | ISO | RGD:70502 | 6480464 | Atrazine results in decreased expression of TP53 mRNA; Atrazine results in decreased expression of TP53 more ... | CTD | PMID:21333729|PMID:22378314|PMID:34435054 |
Tp53 | Rat | atrazine | multiple interactions | EXP | | 6480464 | kolaviron inhibits the reaction [Atrazine affects the expression of TP53] | CTD | PMID:21726175 |
Tp53 | Rat | atrazine | affects expression | EXP | | 6480464 | Atrazine affects the expression of TP53 | CTD | PMID:21726175 |
Tp53 | Rat | atrazine | multiple interactions | ISO | RGD:70502 | 6480464 | kolaviron inhibits the reaction [Atrazine results in decreased expression of TP53 mRNA]; kolaviron inhibits the more ... | CTD | PMID:21333729 |
Tp53 | Rat | atrazine | affects localization | EXP | | 6480464 | Atrazine affects the localization of TP53 protein | CTD | PMID:9486943 |
Tp53 | Rat | atropine | multiple interactions | ISO | RGD:70502 | 6480464 | Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]; Atropine inhibits the more ... | CTD | PMID:12762645 |
Tp53 | Rat | Auriculasin | multiple interactions | ISO | RGD:70502 | 6480464 | [TNFSF10 protein co-treated with auriculasin] results in increased expression of TP53 protein; TNFRSF10B protein affects more ... | CTD | PMID:30817944 |
Tp53 | Rat | aurofusarin | increases expression | ISO | RGD:70502 | 6480464 | aurofusarin results in increased expression of TP53 protein | CTD | PMID:29248571 |
Tp53 | Rat | axitinib | affects activity | ISO | RGD:70502 | 6480464 | Axitinib affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | azadirachtin A | increases expression | ISO | RGD:70502 | 6480464 | azadirachtin results in increased expression of TP53 mRNA; azadirachtin results in increased expression of TP53 more ... | CTD | PMID:20429769 |
Tp53 | Rat | azaribine | affects activity | ISO | RGD:70502 | 6480464 | azaribine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | azathioprine | increases expression | ISO | RGD:70502 | 6480464 | Azathioprine results in increased expression of TP53 protein | CTD | PMID:14961032 |
Tp53 | Rat | azathioprine | increases mutagenesis | ISO | RGD:70502 | 6480464 | Azathioprine results in increased mutagenesis of TP53 gene | CTD | PMID:17979968 |
Tp53 | Rat | azetidine | affects localization | ISO | RGD:11440 | 6480464 | azetidine affects the localization of TRP53 protein | CTD | PMID:18813348 |
Tp53 | Rat | azinphos-ethyl | affects activity | ISO | RGD:70502 | 6480464 | azinphos ethyl metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | azinphos-methyl | affects activity | ISO | RGD:70502 | 6480464 | Azinphosmethyl metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Azoxymethane | increases expression | EXP | | 6480464 | Azoxymethane results in increased expression of TRP53 mRNA | CTD | PMID:20043115 |
Tp53 | Rat | Azoxymethane | increases phosphorylation | EXP | | 6480464 | Azoxymethane results in increased phosphorylation of TP53 protein | CTD | PMID:18239060 |
Tp53 | Rat | bafilomycin A1 | multiple interactions | ISO | RGD:70502 | 6480464 | [bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased more ... | CTD | PMID:23380477 |
Tp53 | Rat | baicalein | increases expression | ISO | RGD:70502 | 6480464 | baicalein results in increased expression of TP53 protein | CTD | PMID:21457722 |
Tp53 | Rat | baicalein | affects binding | ISO | RGD:70502 | 6480464 | baicalein binds to TP53 protein | CTD | PMID:38230788 |
Tp53 | Rat | baicalein | multiple interactions | ISO | RGD:70502 | 6480464 | baicalein inhibits the reaction [Cholesterol, LDL analog results in increased expression of TP53 mRNA]; baicalein more ... | CTD | PMID:37354967|PMID:38230788 |
Tp53 | Rat | baicalein | increases expression | EXP | | 6480464 | baicalein results in increased expression of TP53 protein | CTD | PMID:11513834 |
Tp53 | Rat | baicalin | increases expression | ISO | RGD:70502 | 6480464 | baicalin results in increased expression of TP53 protein | CTD | PMID:21457722 |
Tp53 | Rat | barban | affects activity | ISO | RGD:70502 | 6480464 | barban affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | bathocuproine disulfonic acid | multiple interactions | ISO | RGD:70502 | 6480464 | bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which more ... | CTD | PMID:11964141 |
Tp53 | Rat | belinostat | decreases expression | ISO | RGD:70502 | 6480464 | belinostat results in decreased expression of TP53 mRNA | CTD | PMID:19606018 |
Tp53 | Rat | belinostat | decreases expression | ISO | RGD:11440 | 6480464 | belinostat results in decreased expression of TRP53 mRNA; belinostat results in decreased expression of TRP53 more ... | CTD | PMID:29733868 |
Tp53 | Rat | benomyl | affects activity | ISO | RGD:70502 | 6480464 | Benomyl affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Bensulide | affects activity | ISO | RGD:70502 | 6480464 | bensulide metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | benzalkonium chloride | decreases expression | ISO | RGD:70502 | 6480464 | Benzalkonium Compounds results in decreased expression of TP53 mRNA | CTD | PMID:28236482 |
Tp53 | Rat | benzene | increases phosphorylation | ISO | RGD:70502 | 6480464 | Benzene results in increased phosphorylation of TP53 protein | CTD | PMID:8076368 |
Tp53 | Rat | benzene | multiple interactions | EXP | | 6480464 | Benzene results in increased phosphorylation of and results in increased activity of TP53 protein | CTD | PMID:9118908 |
Tp53 | Rat | benzene | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 SNP affects the susceptibility to Benzene | CTD | PMID:18978339 |
Tp53 | Rat | benzene | decreases expression | ISO | RGD:70502 | 6480464 | Benzene results in decreased expression of TP53 mRNA | CTD | PMID:19505915 |
Tp53 | Rat | benzene | increases mutagenesis | ISO | RGD:70502 | 6480464 | Benzene results in increased mutagenesis of TP53 gene | CTD | PMID:19862502 |
Tp53 | Rat | benzene | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Benzene | CTD | PMID:19326098|PMID:20018183 |
Tp53 | Rat | benzene | increases expression | ISO | RGD:70502 | 6480464 | Benzene results in increased expression of TP53 mRNA | CTD | PMID:21382456 |
Tp53 | Rat | benzene | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 protein affects the reaction [Benzene results in decreased expression of CCR7 mRNA]; TRP53 protein more ... | CTD | PMID:11274754|PMID:11896287|PMID:12857942|PMID:12928149|PMID:15935813 |
Tp53 | Rat | benzene | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in increased susceptibility to Benzene | CTD | PMID:19478238 |
Tp53 | Rat | benzene | increases expression | ISO | RGD:11440 | 6480464 | Benzene results in increased expression of TRP53 mRNA; Benzene results in increased expression of TRP53 more ... | CTD | PMID:11896287|PMID:17162533|PMID:18281070 |
Tp53 | Rat | benzene | increases phosphorylation | EXP | | 6480464 | Benzene results in increased phosphorylation of TP53 protein | CTD | PMID:8076368 |
Tp53 | Rat | benzene | increases expression | EXP | | 6480464 | Benzene results in increased expression of TP53 protein | CTD | PMID:18093815 |
Tp53 | Rat | benzene | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene SNP results in increased susceptibility to Benzene | CTD | PMID:16728435 |
Tp53 | Rat | benzidine | increases expression | ISO | RGD:70502 | 6480464 | benzidine results in increased expression of TP53 protein mutant form | CTD | PMID:15748509|PMID:17690521 |
Tp53 | Rat | benzo[a]pyrene | multiple interactions | ISO | RGD:70502 | 6480464 | 2,4,4'-trichlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression more ... | CTD | PMID:10837373|PMID:11782367|PMID:12807757|PMID:15625077|PMID:15698582|PMID:15837074|PMID:16041517|PMID:16258175|PMID:20840854|PMID:21457773|PMID:22120587|PMID:22266578|PMID:24361490|PMID:24664296|PMID:24954032|PMID:25398514|PMID:25744307|PMID:26343999|PMID:28882572|PMID:29471073|PMID:32553695|PMID:36982514 |
Tp53 | Rat | benzo[a]pyrene | decreases acetylation | ISO | RGD:11440 | 6480464 | Benzo(a)pyrene results in decreased acetylation of TRP53 protein | CTD | PMID:28681665 |
Tp53 | Rat | benzo[a]pyrene | affects methylation | ISO | RGD:70502 | 6480464 | Benzo(a)pyrene affects the methylation of TP53 5' UTR | CTD | PMID:27901495 |
Tp53 | Rat | benzo[a]pyrene | increases mutagenesis | EXP | | 6480464 | Benzo(a)pyrene results in increased mutagenesis of TP53 gene | CTD | PMID:9314051 |
Tp53 | Rat | benzo[a]pyrene | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in increased susceptibility to Benzo(a)pyrene | CTD | PMID:21715664|PMID:25995008 |
Tp53 | Rat | benzo[a]pyrene | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Benzo(a)pyrene | CTD | PMID:25398514 |
Tp53 | Rat | benzo[a]pyrene | increases phosphorylation | ISO | RGD:70502 | 6480464 | Benzo(a)pyrene results in increased phosphorylation of TP53 protein | CTD | PMID:15837074|PMID:24361490|PMID:25744307|PMID:27694624 |
Tp53 | Rat | benzo[a]pyrene | affects phosphorylation | ISO | RGD:70502 | 6480464 | Benzo(a)pyrene affects the phosphorylation of TP53 protein | CTD | PMID:24362009 |
Tp53 | Rat | benzo[a]pyrene | increases mutagenesis | ISO | RGD:70502 | 6480464 | Benzo(a)pyrene results in increased mutagenesis of TP53 gene | CTD | PMID:22319594 |
Tp53 | Rat | benzo[a]pyrene | decreases expression | ISO | RGD:11440 | 6480464 | Benzo(a)pyrene results in decreased expression of TP53 protein; Benzo(a)pyrene results in decreased expression of TRP53 more ... | CTD | PMID:20869020|PMID:22641617|PMID:36193556 |
Tp53 | Rat | benzo[a]pyrene | increases phosphorylation | EXP | | 6480464 | Benzo(a)pyrene results in increased phosphorylation of TP53 protein | CTD | PMID:17961608|PMID:18634860|PMID:34529316 |
Tp53 | Rat | benzo[a]pyrene | increases phosphorylation | ISO | RGD:11440 | 6480464 | Benzo(a)pyrene results in increased phosphorylation of TRP53 protein | CTD | PMID:19041363|PMID:19874837|PMID:22120587|PMID:28681665 |
Tp53 | Rat | benzo[a]pyrene | affects expression | ISO | RGD:70502 | 6480464 | Benzo(a)pyrene affects the expression of TP53; Benzo(a)pyrene affects the expression of TP53 mRNA; Benzo(a)pyrene affects more ... | CTD | PMID:21393351|PMID:24362009|PMID:27825931 |
Tp53 | Rat | benzo[a]pyrene | increases activity | EXP | | 6480464 | Benzo(a)pyrene results in increased activity of TRP53 protein | CTD | PMID:19931295 |
Tp53 | Rat | benzo[a]pyrene | affects localization | ISO | RGD:70502 | 6480464 | Benzo(a)pyrene affects the localization of TP53 protein | CTD | PMID:20840854 |
Tp53 | Rat | benzo[a]pyrene | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 affects the susceptibility to Benzo(a)pyrene; TP53 protein affects the susceptibility to Benzo(a)pyrene | CTD | PMID:10837373|PMID:28882572|PMID:29471073 |
Tp53 | Rat | benzo[a]pyrene | increases expression | ISO | RGD:70502 | 6480464 | Benzo(a)pyrene metabolite results in increased expression of TP53 protein; Benzo(a)pyrene results in increased expression of more ... | CTD | PMID:10837373|PMID:11782367|PMID:12807757|PMID:15548639|PMID:15808406|PMID:16041517|PMID:16258175|PMID:18174961|PMID:19027820|PMID:20064835|PMID:20862736|PMID:21714911|PMID:22044530|PMID:22053912|PMID:22120587|PMID:22227536|PMID:22266578|PMID:22889811|PMID:26343999|PMID:29218508|PMID:31542801|PMID:32087850|PMID:32234424|PMID:32717239|PMID:35641671 |
Tp53 | Rat | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of TP53 mRNA; Benzo(a)pyrene results in increased expression of TP53 more ... | CTD | PMID:19408242|PMID:20064080|PMID:21604763|PMID:34283317|PMID:9789950 |
Tp53 | Rat | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene results in increased mutagenesis of TP53 gene] which affects the folding of TP53 protein; more ... | CTD | PMID:15459018|PMID:19408242|PMID:20064080|PMID:21745554|PMID:34529316|PMID:9314051 |
Tp53 | Rat | benzo[a]pyrene | increases activity | ISO | RGD:70502 | 6480464 | Benzo(a)pyrene results in increased activity of TP53 protein | CTD | PMID:12807757 |
Tp53 | Rat | benzo[a]pyrene | affects activity | ISO | RGD:70502 | 6480464 | Benzo(a)pyrene affects the activity of TP53 protein | CTD | PMID:20624995 |
Tp53 | Rat | benzo[a]pyrene | decreases expression | ISO | RGD:70502 | 6480464 | Benzo(a)pyrene results in decreased expression of TP53 mRNA; Benzo(a)pyrene results in decreased expression of TP53 more ... | CTD | PMID:18247414|PMID:29126329 |
Tp53 | Rat | benzo[a]pyrene | increases expression | ISO | RGD:11440 | 6480464 | Benzo(a)pyrene metabolite results in increased expression of TRP53 protein modified form; Benzo(a)pyrene results in increased more ... | CTD | PMID:18656336|PMID:19428948|PMID:19896525|PMID:19961161|PMID:21745588|PMID:22120587|PMID:25230394|PMID:28032951|PMID:32553695 |
Tp53 | Rat | benzo[a]pyrene | affects localization | ISO | RGD:11440 | 6480464 | Benzo(a)pyrene affects the localization of TRP53 protein | CTD | PMID:17240030|PMID:9006915 |
Tp53 | Rat | benzo[a]pyrene | multiple interactions | ISO | RGD:11440 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... | CTD | PMID:11096091|PMID:18656336|PMID:20570689|PMID:20869020|PMID:22120587|PMID:23052197|PMID:27858113|PMID:28032951|PMID:28681665|PMID:36193556|PMID:9006915 |
Tp53 | Rat | benzo[a]pyrene diol epoxide I | multiple interactions | ISO | RGD:70502 | 6480464 | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TP53 protein]; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide more ... | CTD | PMID:11782367|PMID:12727806|PMID:18085531|PMID:21983885 |
Tp53 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:70502 | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TP53 mRNA | CTD | PMID:34454013 |
Tp53 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | RGD:11440 | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TRP53 mRNA; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression more ... | CTD | PMID:19428948|PMID:24837741 |
Tp53 | Rat | benzo[a]pyrene diol epoxide I | affects binding | ISO | RGD:70502 | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide binds to TP53 gene | CTD | PMID:12727806 |
Tp53 | Rat | benzo[a]pyrene diol epoxide I | increases phosphorylation | ISO | RGD:70502 | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of TP53 protein | CTD | PMID:20382639 |
Tp53 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | RGD:70502 | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TP53 mRNA; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression more ... | CTD | PMID:11782367|PMID:19150397|PMID:20382639 |
Tp53 | Rat | benzo[a]pyrene diol epoxide I | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | CTD | PMID:21983885 |
Tp53 | Rat | Benzo[a]pyrene-7,8-diol | multiple interactions | ISO | RGD:70502 | 6480464 | [TP53 protein results in increased susceptibility to Etoposide] which results in decreased chemical synthesis of more ... | CTD | PMID:15698582|PMID:29471073 |
Tp53 | Rat | Benzo[a]pyrene-7,8-diol | increases chemical synthesis | ISO | RGD:70502 | 6480464 | TP53 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol | CTD | PMID:29471073 |
Tp53 | Rat | benzo[b]fluoranthene | increases expression | ISO | RGD:70502 | 6480464 | benzo(b)fluoranthene results in increased expression of TP53 protein | CTD | PMID:21776270 |
Tp53 | Rat | benzo[b]fluoranthene | affects activity | ISO | RGD:70502 | 6480464 | benzo(b)fluoranthene affects the activity of TP53 protein; benzo(b)fluoranthene metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | benzo[b]fluoranthene | multiple interactions | ISO | RGD:11440 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... | CTD | PMID:27858113 |
Tp53 | Rat | BENZO[G]CHRYSENE | increases phosphorylation | EXP | | 6480464 | benzo(g)chrysene results in increased phosphorylation of TP53 protein | CTD | PMID:17961608 |
Tp53 | Rat | Benzo[k]fluoranthene | affects activity | ISO | RGD:70502 | 6480464 | benzo(k)fluoranthene affects the activity of TP53 protein; benzo(k)fluoranthene metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | berberine | increases expression | ISO | RGD:70502 | 6480464 | Berberine results in increased expression of TP53 mRNA; Berberine results in increased expression of TP53 more ... | CTD | PMID:20656010 |
Tp53 | Rat | berberine | multiple interactions | ISO | RGD:70502 | 6480464 | [Berberine co-treated with Niacinamide] results in increased expression of and results in increased acetylation of more ... | CTD | PMID:26712469 |
Tp53 | Rat | beryllium dichloride | increases expression | ISO | RGD:11440 | 6480464 | beryllium chloride results in increased expression of TRP53 mRNA | CTD | PMID:23793613 |
Tp53 | Rat | beryllium sulfate | multiple interactions | ISO | RGD:70502 | 6480464 | beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter] | CTD | PMID:17395767 |
Tp53 | Rat | beryllium sulfate | increases expression | ISO | RGD:70502 | 6480464 | beryllium sulfate results in increased expression of TP53 protein | CTD | PMID:17395767|PMID:20974702 |
Tp53 | Rat | Besigomsin | multiple interactions | ISO | RGD:11440 | 6480464 | schizandrol B inhibits the reaction [Acetaminophen results in increased activity of TRP53 protein]; schizandrol B more ... | CTD | PMID:25319358 |
Tp53 | Rat | beta-carboline | affects activity | ISO | RGD:70502 | 6480464 | norharman metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | beta-D-fructofuranose 1,6-bisphosphate | increases expression | ISO | RGD:70502 | 6480464 | fructose-1,6-diphosphate results in increased expression of TP53 protein | CTD | PMID:33078453 |
Tp53 | Rat | beta-lapachone | decreases expression | ISO | RGD:70502 | 6480464 | beta-lapachone results in decreased expression of TP53 mRNA | CTD | PMID:38218311 |
Tp53 | Rat | beta-naphthoflavone | multiple interactions | ISO | RGD:70502 | 6480464 | [beta-Naphthoflavone binds to and results in increased activity of AHR protein] results in decreased susceptibility more ... | CTD | PMID:22044530 |
Tp53 | Rat | betalain | increases expression | ISO | RGD:70502 | 6480464 | Betalains results in increased expression of TP53 mRNA | CTD | PMID:33522684 |
Tp53 | Rat | betaxolol | multiple interactions | ISO | RGD:70502 | 6480464 | Betaxolol results in increased expression of and results in increased phosphorylation of TP53 protein | CTD | PMID:38325520 |
Tp53 | Rat | betulinic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [Betulinic Acid co-treated with Oxygen deficiency] results in increased expression of TP53 protein | CTD | PMID:33181113 |
Tp53 | Rat | betulinic acid | increases expression | ISO | RGD:70502 | 6480464 | Betulinic Acid results in increased expression of TP53 protein | CTD | PMID:33181113 |
Tp53 | Rat | bexarotene | multiple interactions | ISO | RGD:70502 | 6480464 | bexarotene results in increased phosphorylation of and results in increased activity of TP53 protein | CTD | PMID:19067706 |
Tp53 | Rat | bicalutamide | increases expression | ISO | RGD:70502 | 6480464 | bicalutamide results in increased expression of TP53 protein | CTD | PMID:15638997 |
Tp53 | Rat | bicalutamide | multiple interactions | ISO | RGD:70502 | 6480464 | bicalutamide inhibits the reaction [bisphenol A results in increased phosphorylation of TP53 protein] | CTD | PMID:29383186 |
Tp53 | Rat | bifenthrin | increases expression | ISO | RGD:11440 | 6480464 | bifenthrin results in increased expression of TRP53 mRNA | CTD | PMID:20097460|PMID:27916261 |
Tp53 | Rat | bifenthrin | decreases expression | ISO | RGD:11440 | 6480464 | bifenthrin results in decreased expression of TRP53 mRNA | CTD | PMID:26071804 |
Tp53 | Rat | biphenyl-2-ol | multiple interactions | ISO | RGD:70502 | 6480464 | [2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene; more ... | CTD | PMID:10334203 |
Tp53 | Rat | biphenyl-4-amine | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to 4-biphenylamine | CTD | PMID:11804609 |
Tp53 | Rat | biphenyl-4-amine | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine affects the reaction [4-biphenylamine affects the expression of TP53 protein]; TP53 protein inhibits the more ... | CTD | PMID:32905825 |
Tp53 | Rat | biphenyl-4-amine | decreases expression | ISO | RGD:70502 | 6480464 | 4-biphenylamine results in decreased expression of TP53 mRNA | CTD | PMID:32905825 |
Tp53 | Rat | biphenyl-4-amine | affects expression | ISO | RGD:70502 | 6480464 | 4-biphenylamine affects the expression of TP53 protein | CTD | PMID:32905825 |
Tp53 | Rat | biphenyl-4-amine | affects binding | ISO | RGD:70502 | 6480464 | 4-biphenylamine binds to TP53 gene | CTD | PMID:12376482 |
Tp53 | Rat | bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:11440 | 6480464 | Mustard Gas results in increased expression of TRP53 protein | CTD | PMID:19560481 |
Tp53 | Rat | bis(2-chloroethyl) sulfide | decreases expression | ISO | RGD:11440 | 6480464 | Mustard Gas results in decreased expression of TRP53 mRNA | CTD | PMID:19778212 |
Tp53 | Rat | bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:70502 | 6480464 | Mustard Gas results in increased expression of TP53 protein; Mustard Gas results in increased expression more ... | CTD | PMID:11428642|PMID:19748996|PMID:22119920|PMID:25102026|PMID:9665388 |
Tp53 | Rat | bis(2-chloroethyl) sulfide | increases phosphorylation | ISO | RGD:70502 | 6480464 | Mustard Gas results in increased phosphorylation of TP53 protein | CTD | PMID:19845377|PMID:20143454|PMID:22119920 |
Tp53 | Rat | bis(2-chloroethyl) sulfide | multiple interactions | ISO | RGD:70502 | 6480464 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Mustard Gas results in increased expression of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits more ... | CTD | PMID:22119920 |
Tp53 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:11440 | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated more ... | CTD | PMID:20659492|PMID:35739755|PMID:36583613 |
Tp53 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:11440 | 6480464 | Diethylhexyl Phthalate results in increased expression of TP53 mRNA | CTD | PMID:36583613 |
Tp53 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:70502 | 6480464 | Diethylhexyl Phthalate results in decreased expression of TP53 mRNA; Diethylhexyl Phthalate results in decreased expression more ... | CTD | PMID:37734194 |
Tp53 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:70502 | 6480464 | KLF7 protein inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of TP53 mRNA]; KLF7 more ... | CTD | PMID:37734194 |
Tp53 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:70502 | 6480464 | Diethylhexyl Phthalate results in increased expression of TP53 protein | CTD | PMID:31163220 |
Tp53 | Rat | bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of TP53 mRNA; Diethylhexyl Phthalate results in increased expression more ... | CTD | PMID:28115068|PMID:32710958 |
Tp53 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | Ethanol promotes the reaction [Diethylhexyl Phthalate results in increased expression of TP53 mRNA] | CTD | PMID:28115068 |
Tp53 | Rat | Bisoxatin acetate | affects activity | ISO | RGD:70502 | 6480464 | bisoxatin acetate affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TP53 mRNA; bisphenol A results in increased expression more ... | CTD | PMID:23146694|PMID:25344109|PMID:25454643|PMID:27208089|PMID:27296223|PMID:27539358|PMID:32172062|PMID:32428650|PMID:32810514|PMID:34505250|PMID:38513920 |
Tp53 | Rat | bisphenol A | decreases methylation | ISO | RGD:70502 | 6480464 | bisphenol A results in decreased methylation of TP53 gene | CTD | PMID:38338858 |
Tp53 | Rat | bisphenol A | increases expression | ISO | RGD:11440 | 6480464 | bisphenol A results in increased expression of TP53 protein; bisphenol A results in increased expression more ... | CTD | PMID:36633214|PMID:38021376|PMID:38725370 |
Tp53 | Rat | bisphenol A | affects expression | ISO | RGD:11440 | 6480464 | bisphenol A affects the expression of TRP53 protein | CTD | PMID:33509759 |
Tp53 | Rat | bisphenol A | multiple interactions | ISO | RGD:11440 | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated more ... | CTD | PMID:35739755|PMID:36633214|PMID:38725370 |
Tp53 | Rat | bisphenol A | increases phosphorylation | ISO | RGD:70502 | 6480464 | bisphenol A results in increased phosphorylation of TP53 protein | CTD | PMID:29275510|PMID:29383186|PMID:32466334|PMID:36232920 |
Tp53 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TP53 gene | CTD | PMID:28505145 |
Tp53 | Rat | bisphenol A | increases expression | ISO | RGD:70502 | 6480464 | bisphenol A analog results in increased expression of TP53 mRNA; bisphenol A results in increased more ... | CTD | PMID:21277958|PMID:24831732|PMID:29128613|PMID:29275510|PMID:31681507|PMID:32387340|PMID:36572933|PMID:36633214 |
Tp53 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TP53 mRNA | CTD | PMID:25181051 |
Tp53 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with naringin] results in decreased expression of TP53 protein; [bisphenol A co-treated more ... | CTD | PMID:25454643|PMID:32172062|PMID:32428650|PMID:32810514|PMID:34505250|PMID:38513920 |
Tp53 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A analog results in decreased expression of TP53 mRNA; bisphenol A analog results in more ... | CTD | PMID:26982218|PMID:33296240|PMID:35427877 |
Tp53 | Rat | bisphenol A | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased phosphorylation of TP53 protein]; bicalutamide inhibits more ... | CTD | PMID:23222814|PMID:24831732|PMID:28238728|PMID:29383186|PMID:31681507|PMID:36633214|PMID:37009741 |
Tp53 | Rat | bisphenol A | decreases expression | ISO | RGD:70502 | 6480464 | bisphenol A results in decreased expression of TP53 mRNA; bisphenol A results in decreased expression more ... | CTD | PMID:23222814|PMID:27998958|PMID:28238728 |
Tp53 | Rat | bisphenol AF | affects activity | ISO | RGD:70502 | 6480464 | bisphenol AF affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | bisphenol F | increases expression | ISO | RGD:11440 | 6480464 | bisphenol F results in increased expression of TRP53 protein | CTD | PMID:29102535 |
Tp53 | Rat | bisphenol F | decreases methylation | ISO | RGD:70502 | 6480464 | bisphenol F results in decreased methylation of TP53 gene | CTD | PMID:38338858 |
Tp53 | Rat | bisphenol F | decreases expression | ISO | RGD:11440 | 6480464 | bisphenol F results in decreased expression of TRP53 mRNA | CTD | PMID:38685157 |
Tp53 | Rat | bisphenol F | decreases expression | ISO | RGD:70502 | 6480464 | bisphenol F results in decreased expression of TP53 mRNA | CTD | PMID:31875995 |
Tp53 | Rat | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of TP53 protein | CTD | PMID:37601897 |
Tp53 | Rat | bisphenol F diglycidyl ether | affects activity | ISO | RGD:70502 | 6480464 | bisphenol F diglycidyl ether affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | bithionol | affects activity | ISO | RGD:70502 | 6480464 | Bithionol affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | bleomycin A2 | increases expression | ISO | RGD:11440 | 6480464 | Bleomycin results in increased expression of TRP53 protein | CTD | PMID:9683175 |
Tp53 | Rat | bleomycin A2 | increases phosphorylation | ISO | RGD:70502 | 6480464 | Bleomycin results in increased phosphorylation of TP53 protein | CTD | PMID:24933654 |
Tp53 | Rat | bleomycin A2 | increases expression | ISO | RGD:70502 | 6480464 | Bleomycin results in increased expression of TP53 mRNA | CTD | PMID:26800624 |
Tp53 | Rat | bleomycin A2 | multiple interactions | ISO | RGD:70502 | 6480464 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 more ... | CTD | PMID:24933654|PMID:26800624 |
Tp53 | Rat | bleomycin A2 | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Bleomycin | CTD | PMID:20135637 |
Tp53 | Rat | boric acid | decreases expression | ISO | RGD:11440 | 6480464 | boric acid results in decreased expression of TRP53 mRNA | CTD | PMID:31368021 |
Tp53 | Rat | bortezomib | multiple interactions | ISO | RGD:70502 | 6480464 | [CASP8 protein results in increased activity of CASP3 protein] affects the reaction [Bortezomib results in more ... | CTD | PMID:12393500|PMID:16373703|PMID:16617327|PMID:17351739 |
Tp53 | Rat | bortezomib | affects activity | ISO | RGD:70502 | 6480464 | Bortezomib affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | bortezomib | increases activity | ISO | RGD:70502 | 6480464 | Bortezomib results in increased activity of TP53 protein | CTD | PMID:30818834 |
Tp53 | Rat | bortezomib | multiple interactions | ISO | RGD:11440 | 6480464 | [SCIO-469 co-treated with Bortezomib] results in increased expression of TRP53 protein | CTD | PMID:16617327 |
Tp53 | Rat | bortezomib | increases stability | ISO | RGD:70502 | 6480464 | Bortezomib results in increased stability of TP53 protein | CTD | PMID:15543232 |
Tp53 | Rat | bortezomib | increases expression | ISO | RGD:70502 | 6480464 | Bortezomib results in increased expression of TP53 protein | CTD | PMID:12393500|PMID:15173093|PMID:16617327|PMID:17898295|PMID:18534018|PMID:18790767|PMID:21532991|PMID:36401358 |
Tp53 | Rat | bosutinib | affects activity | ISO | RGD:70502 | 6480464 | bosutinib analog affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | brassinolide | increases expression | ISO | RGD:70502 | 6480464 | brassinolide results in increased expression of TP53 protein | CTD | PMID:20833159 |
Tp53 | Rat | bromochloroacetic acid | multiple interactions | EXP | | 6480464 | bromochloroacetic acid promotes the reaction [Bromates results in increased phosphorylation of TP53 protein] | CTD | PMID:21864635 |
Tp53 | Rat | Bromofos | affects activity | ISO | RGD:70502 | 6480464 | bromophos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Bromophos-ethyl | affects activity | ISO | RGD:70502 | 6480464 | ethyl bromophos affects the activity of TP53 protein; ethyl bromophos metabolite affects the activity of more ... | CTD | PMID:35435491 |
Tp53 | Rat | bromuconazole | increases expression | EXP | | 6480464 | bromuconazole results in increased expression of TP53 mRNA | CTD | PMID:36370923 |
Tp53 | Rat | bucladesine | multiple interactions | ISO | RGD:70502 | 6480464 | [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression more ... | CTD | PMID:22534328 |
Tp53 | Rat | budesonide | decreases expression | ISO | RGD:70502 | 6480464 | Budesonide results in decreased expression of TP53 protein | CTD | PMID:15475437 |
Tp53 | Rat | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of TP53 mRNA | CTD | PMID:24136188 |
Tp53 | Rat | busulfan | multiple interactions | ISO | RGD:70502 | 6480464 | Busulfan affects the phosphorylation of and affects the activity of TP53 protein | CTD | PMID:16882877 |
Tp53 | Rat | busulfan | increases expression | ISO | RGD:70502 | 6480464 | Busulfan results in increased expression of TP53 mRNA | CTD | PMID:35641671 |
Tp53 | Rat | buta-1,3-diene | decreases expression | ISO | RGD:11440 | 6480464 | 1,3-butadiene results in decreased expression of TRP53 mRNA | CTD | PMID:29038090 |
Tp53 | Rat | butanal | decreases expression | ISO | RGD:70502 | 6480464 | butyraldehyde results in decreased expression of TP53 mRNA | CTD | PMID:26079696 |
Tp53 | Rat | butane-2,3-dione | increases expression | ISO | RGD:11440 | 6480464 | Diacetyl results in increased expression of TRP53 mRNA | CTD | PMID:37399938 |
Tp53 | Rat | butylated hydroxyanisole | multiple interactions | EXP | | 6480464 | Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TP53 protein] | CTD | PMID:18593901 |
Tp53 | Rat | butylated hydroxyanisole | multiple interactions | ISO | RGD:11440 | 6480464 | Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein] | CTD | PMID:18593901 |
Tp53 | Rat | Butylbenzyl phthalate | increases methylation | ISO | RGD:70502 | 6480464 | butylbenzyl phthalate results in increased methylation of TP53 promoter | CTD | PMID:35487445 |
Tp53 | Rat | Butylbenzyl phthalate | multiple interactions | ISO | RGD:11440 | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated more ... | CTD | PMID:35739755 |
Tp53 | Rat | Butylbenzyl phthalate | decreases expression | ISO | RGD:70502 | 6480464 | butylbenzyl phthalate results in decreased expression of TP53 mRNA | CTD | PMID:31016752|PMID:35487445 |
Tp53 | Rat | butyric acid | multiple interactions | ISO | RGD:70502 | 6480464 | [1'-acetoxychavicol acetate co-treated with Butyric Acid] results in increased phosphorylation of TP53 protein | CTD | PMID:24480522 |
Tp53 | Rat | butyric acid | decreases expression | ISO | RGD:70502 | 6480464 | Butyric Acid results in decreased expression of TP53 mRNA | CTD | PMID:34581912 |
Tp53 | Rat | butyric acid | increases expression | ISO | RGD:11440 | 6480464 | Butyric Acid results in increased expression of TP53 mRNA | CTD | PMID:37341073 |
Tp53 | Rat | butyric acid | multiple interactions | ISO | RGD:11440 | 6480464 | [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in more ... | CTD | PMID:25478867 |
Tp53 | Rat | C.I. Natural Red 20 | increases expression | ISO | RGD:70502 | 6480464 | shikonin results in increased expression of TP53 protein | CTD | PMID:28684144 |
Tp53 | Rat | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of TP53 mRNA | CTD | PMID:19167457 |
Tp53 | Rat | C60 fullerene | multiple interactions | ISO | RGD:70502 | 6480464 | fullerene C60 analog results in increased phosphorylation of and results in increased expression of TP53 more ... | CTD | PMID:20045429 |
Tp53 | Rat | cadmium acetate | increases phosphorylation | ISO | RGD:70502 | 6480464 | cadmium acetate results in increased phosphorylation of TP53 protein | CTD | PMID:20839231 |
Tp53 | Rat | cadmium acetate | decreases expression | ISO | RGD:70502 | 6480464 | cadmium acetate results in decreased expression of TP53 mRNA | CTD | PMID:18155341 |
Tp53 | Rat | cadmium acetate | multiple interactions | ISO | RGD:70502 | 6480464 | cadmium acetate results in increased degradation of and affects the localization of TP53 protein | CTD | PMID:15450950 |
Tp53 | Rat | cadmium atom | increases expression | ISO | RGD:11440 | 6480464 | Cadmium results in increased expression of TP53 protein; Cadmium results in increased expression of TRP53 more ... | CTD | PMID:12189181|PMID:21467746|PMID:23095357 |
Tp53 | Rat | cadmium atom | decreases expression | ISO | RGD:70502 | 6480464 | Cadmium results in decreased expression of TP53 protein mutant form | CTD | PMID:28507149 |
Tp53 | Rat | cadmium atom | increases activity | ISO | RGD:11440 | 6480464 | Cadmium results in increased activity of TRP53 protein | CTD | PMID:22634143 |
Tp53 | Rat | cadmium atom | affects folding | ISO | RGD:11440 | 6480464 | Cadmium affects the folding of TRP53 protein | CTD | PMID:8467489 |
Tp53 | Rat | cadmium atom | increases phosphorylation | EXP | | 6480464 | Cadmium results in increased phosphorylation of TP53 protein | CTD | PMID:18463101|PMID:27658547 |
Tp53 | Rat | cadmium atom | increases expression | EXP | | 6480464 | Cadmium results in increased expression of TP53 protein | CTD | PMID:24212999 |
Tp53 | Rat | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of and more ... | CTD | PMID:18463101|PMID:21467746|PMID:27658547|PMID:33031904 |
Tp53 | Rat | cadmium atom | increases expression | ISO | RGD:70502 | 6480464 | Cadmium results in increased expression of TP53 protein | CTD | PMID:12189181|PMID:28507149|PMID:32976933 |
Tp53 | Rat | cadmium atom | decreases activity | ISO | RGD:11440 | 6480464 | Cadmium results in decreased activity of TRP53 protein | CTD | PMID:10531375 |
Tp53 | Rat | cadmium atom | increases activity | EXP | | 6480464 | Cadmium results in increased activity of TP53 protein | CTD | PMID:16730872 |
Tp53 | Rat | cadmium atom | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Cadmium | CTD | PMID:17174997 |
Tp53 | Rat | cadmium atom | multiple interactions | ISO | RGD:70502 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which affects the folding of TP53 protein; more ... | CTD | PMID:10531375|PMID:17174997|PMID:21605570|PMID:28507149|PMID:33040242|PMID:35301059|PMID:35504338 |
Tp53 | Rat | cadmium atom | affects localization | ISO | RGD:70502 | 6480464 | Cadmium affects the localization of TP53 protein | CTD | PMID:25101185 |
Tp53 | Rat | cadmium atom | multiple interactions | ISO | RGD:11440 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TRP53 more ... | CTD | PMID:12189181|PMID:32199951|PMID:37022104 |
Tp53 | Rat | cadmium dichloride | affects phosphorylation | ISO | RGD:70502 | 6480464 | Cadmium Chloride affects the phosphorylation of TP53 protein | CTD | PMID:23941782 |
Tp53 | Rat | cadmium dichloride | increases acetylation | EXP | | 6480464 | Cadmium Chloride results in increased acetylation of TP53 protein | CTD | PMID:36493885 |
Tp53 | Rat | cadmium dichloride | decreases expression | ISO | RGD:70502 | 6480464 | Cadmium Chloride results in decreased expression of TP53 mRNA | CTD | PMID:38568856 |
Tp53 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of TP53 mRNA | CTD | PMID:30606898|PMID:31077537 |
Tp53 | Rat | cadmium dichloride | affects activity | ISO | RGD:70502 | 6480464 | Cadmium Chloride affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | cadmium dichloride | affects expression | EXP | | 6480464 | Cadmium Chloride affects the expression of TP53 mRNA | CTD | PMID:10647914 |
Tp53 | Rat | cadmium dichloride | decreases activity | ISO | RGD:70502 | 6480464 | Cadmium Chloride results in decreased activity of TP53 protein | CTD | PMID:25446071 |
Tp53 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of TP53 mRNA; Cadmium Chloride results in increased expression more ... | CTD | PMID:16600092|PMID:19615436|PMID:21181359|PMID:23405080|PMID:24492640|PMID:36493885|PMID:37451666 |
Tp53 | Rat | cadmium dichloride | affects localization | ISO | RGD:70502 | 6480464 | Cadmium Chloride affects the localization of TP53 protein | CTD | PMID:25118938 |
Tp53 | Rat | cadmium dichloride | increases activity | ISO | RGD:11440 | 6480464 | Cadmium Chloride results in increased activity of TRP53 protein | CTD | PMID:23376140 |
Tp53 | Rat | cadmium dichloride | increases expression | ISO | RGD:70502 | 6480464 | Cadmium Chloride results in increased expression of TP53 mRNA; Cadmium Chloride results in increased expression more ... | CTD | PMID:12676607|PMID:23941782|PMID:25111876|PMID:26472689|PMID:32512071 |
Tp53 | Rat | cadmium dichloride | increases expression | ISO | RGD:11440 | 6480464 | Cadmium Chloride results in increased expression of TP53 protein; Cadmium Chloride results in increased expression more ... | CTD | PMID:15501611|PMID:18974090|PMID:22314386|PMID:23376140|PMID:25111876 |
Tp53 | Rat | cadmium dichloride | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Cadmium Chloride | CTD | PMID:21252392 |
Tp53 | Rat | cadmium dichloride | decreases activity | ISO | RGD:11440 | 6480464 | Cadmium Chloride results in decreased activity of TRP53 protein | CTD | PMID:10531375 |
Tp53 | Rat | cadmium dichloride | multiple interactions | ISO | RGD:11440 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TRP53 more ... | CTD | PMID:11516527|PMID:12135628|PMID:21252392|PMID:23880315|PMID:32199951|PMID:37022104 |
Tp53 | Rat | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of TP53 mRNA; [Cadmium Chloride more ... | CTD | PMID:16600092|PMID:24492640|PMID:31077537|PMID:33031904|PMID:36493885|PMID:37451666 |
Tp53 | Rat | cadmium dichloride | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Cadmium Chloride | CTD | PMID:17174997 |
Tp53 | Rat | cadmium dichloride | increases activity | EXP | | 6480464 | Cadmium Chloride results in increased activity of TP53 protein | CTD | PMID:16730872 |
Tp53 | Rat | cadmium dichloride | increases phosphorylation | ISO | RGD:70502 | 6480464 | Cadmium Chloride results in increased phosphorylation of TP53 protein | CTD | PMID:12676607 |
Tp53 | Rat | cadmium dichloride | multiple interactions | ISO | RGD:70502 | 6480464 | [Cadmium Chloride results in decreased activity of TP53 protein] inhibits the reaction [TP53 protein binds more ... | CTD | PMID:10531375|PMID:17174997|PMID:23941782|PMID:25118938|PMID:25446071|PMID:25744307|PMID:33040242|PMID:35301059|PMID:35504338 |
Tp53 | Rat | caffeine | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TP53 more ... | CTD | PMID:12393500|PMID:16024610|PMID:16777994|PMID:17919456|PMID:17977830|PMID:19028473|PMID:19735649|PMID:22226932|PMID:22927544|PMID:23274516|PMID:23523585|PMID:30555576|PMID:31168028 |
Tp53 | Rat | caffeine | decreases phosphorylation | ISO | RGD:70502 | 6480464 | Caffeine results in decreased phosphorylation of TP53 protein | CTD | PMID:35688186 |
Tp53 | Rat | caffeine | multiple interactions | ISO | RGD:11440 | 6480464 | 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TRP53 more ... | CTD | PMID:12907610|PMID:30555576 |
Tp53 | Rat | caffeine | decreases mutagenesis | ISO | RGD:11440 | 6480464 | Caffeine results in decreased mutagenesis of TRP53 gene | CTD | PMID:15975959 |
Tp53 | Rat | caffeine | multiple interactions | EXP | | 6480464 | Caffeine inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 protein]; Caffeine inhibits the more ... | CTD | PMID:11751435 |
Tp53 | Rat | caffeine | increases phosphorylation | ISO | RGD:70502 | 6480464 | Caffeine results in increased phosphorylation of TP53 protein | CTD | PMID:12811820 |
Tp53 | Rat | Calcimycin | multiple interactions | ISO | RGD:70502 | 6480464 | [[Air Pollutants results in increased abundance of Particulate Matter] which co-treated with Calcimycin] affects the more ... | CTD | PMID:26419736 |
Tp53 | Rat | Calcimycin | increases expression | ISO | RGD:70502 | 6480464 | Calcimycin results in increased expression of TP53 mRNA | CTD | PMID:26419736 |
Tp53 | Rat | calcitriol | increases expression | ISO | RGD:70502 | 6480464 | Calcitriol results in increased expression of TP53 protein | CTD | PMID:12071473 |
Tp53 | Rat | calcitriol | decreases expression | ISO | RGD:11440 | 6480464 | Calcitriol results in decreased expression of TP53 protein | CTD | PMID:38725370 |
Tp53 | Rat | calcitriol | multiple interactions | ISO | RGD:11440 | 6480464 | Calcitriol inhibits the reaction [bisphenol A results in increased expression of TP53 protein] | CTD | PMID:38725370 |
Tp53 | Rat | calcium atom | decreases expression | ISO | RGD:70502 | 6480464 | Calcium results in decreased expression of TP53 protein | CTD | PMID:16043423 |
Tp53 | Rat | calcium atom | affects localization | ISO | RGD:70502 | 6480464 | TP53 protein affects the localization of Calcium | CTD | PMID:15059885 |
Tp53 | Rat | calcium silicate | increases expression | ISO | RGD:11440 | 6480464 | calcium silicate results in increased expression of TRP53 mRNA | CTD | PMID:29279043 |
Tp53 | Rat | calcium(0) | decreases expression | ISO | RGD:70502 | 6480464 | Calcium results in decreased expression of TP53 protein | CTD | PMID:16043423 |
Tp53 | Rat | calcium(0) | affects localization | ISO | RGD:70502 | 6480464 | TP53 protein affects the localization of Calcium | CTD | PMID:15059885 |
Tp53 | Rat | calyculin A | multiple interactions | ISO | RGD:70502 | 6480464 | calyculin A inhibits the reaction [N-caproylsphingosine affects the splicing of and results in increased expression more ... | CTD | PMID:25195822 |
Tp53 | Rat | camptothecin | multiple interactions | EXP | | 6480464 | Camptothecin promotes the reaction [TP53 protein binds to CREBBP protein]; pifithrin inhibits the reaction [Camptothecin more ... | CTD | PMID:11279278|PMID:13679428 |
Tp53 | Rat | camptothecin | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Camptothecin | CTD | PMID:20477944 |
Tp53 | Rat | camptothecin | decreases acetylation | ISO | RGD:70502 | 6480464 | Camptothecin results in decreased acetylation of TP53 protein | CTD | PMID:24726431 |
Tp53 | Rat | camptothecin | increases expression | ISO | RGD:70502 | 6480464 | Camptothecin results in increased expression of TP53 protein | CTD | PMID:12082016|PMID:17555331|PMID:19481069|PMID:20978201|PMID:24726431|PMID:9673414 |
Tp53 | Rat | camptothecin | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Camptothecin | CTD | PMID:23285096|PMID:9673414 |
Tp53 | Rat | camptothecin | increases phosphorylation | EXP | | 6480464 | Camptothecin results in increased phosphorylation of TP53 protein | CTD | PMID:13679428 |
Tp53 | Rat | camptothecin | increases activity | EXP | | 6480464 | Camptothecin results in increased activity of TP53 protein | CTD | PMID:11279278|PMID:13679428 |
Tp53 | Rat | camptothecin | increases glutathionylation | ISO | RGD:70502 | 6480464 | Camptothecin results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | camptothecin | multiple interactions | ISO | RGD:70502 | 6480464 | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole promotes the reaction [Camptothecin results in increased expression of TP53 protein]; [SIRT1 mutant form more ... | CTD | PMID:11741290|PMID:17555331|PMID:19481069|PMID:24726431 |
Tp53 | Rat | camptothecin | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 mutant form results in decreased susceptibility to Camptothecin; TP53 protein mutant form results in more ... | CTD | PMID:10692111|PMID:24726431|PMID:25269479 |
Tp53 | Rat | camptothecin | increases phosphorylation | ISO | RGD:70502 | 6480464 | Camptothecin results in increased phosphorylation of TP53 protein | CTD | PMID:17555331|PMID:26657896 |
Tp53 | Rat | candesartan | increases expression | EXP | | 6480464 | candesartan results in increased expression of TP53 mRNA; candesartan results in increased expression of TP53 more ... | CTD | PMID:11409658 |
Tp53 | Rat | cannabidiol | decreases expression | EXP | | 6480464 | Cannabidiol results in decreased expression of TP53 mRNA | CTD | PMID:32553926 |
Tp53 | Rat | cannabidiol | increases expression | ISO | RGD:70502 | 6480464 | Cannabidiol results in increased expression of TP53 mRNA; Cannabidiol results in increased expression of TP53 more ... | CTD | PMID:27918106|PMID:32992648|PMID:38342230 |
Tp53 | Rat | cannabidiol | multiple interactions | ISO | RGD:70502 | 6480464 | [Cannabidiol co-treated with moringin] results in decreased expression of TP53 mRNA; [Oxygen co-treated with Ozone] more ... | CTD | PMID:30096889|PMID:32992648|PMID:36519830 |
Tp53 | Rat | cannabidiol | decreases expression | ISO | RGD:70502 | 6480464 | Cannabidiol results in decreased expression of TP53 mRNA; Cannabidiol results in decreased expression of TP53 more ... | CTD | PMID:30713602|PMID:31349651|PMID:33244087 |
Tp53 | Rat | capsaicin | increases expression | ISO | RGD:70502 | 6480464 | Capsaicin results in increased expression of TP53 mRNA; Capsaicin results in increased expression of TP53 more ... | CTD | PMID:16540674|PMID:18991268|PMID:19331147|PMID:19502594|PMID:19846903|PMID:20646592|PMID:22226932|PMID:9461043 |
Tp53 | Rat | capsaicin | increases expression | ISO | RGD:11440 | 6480464 | Capsaicin results in increased expression of TRP53 | CTD | PMID:20069556 |
Tp53 | Rat | capsaicin | decreases degradation | ISO | RGD:70502 | 6480464 | Capsaicin results in decreased degradation of TP53 protein | CTD | PMID:17292493 |
Tp53 | Rat | capsaicin | increases degradation | ISO | RGD:70502 | 6480464 | Capsaicin results in increased degradation of TP53 protein | CTD | PMID:19699254 |
Tp53 | Rat | capsaicin | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 affects the susceptibility to Capsaicin | CTD | PMID:19846903 |
Tp53 | Rat | capsaicin | increases phosphorylation | ISO | RGD:70502 | 6480464 | Capsaicin results in increased phosphorylation of TP53 protein | CTD | PMID:14871840 |
Tp53 | Rat | capsaicin | multiple interactions | ISO | RGD:70502 | 6480464 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity more ... | CTD | PMID:14871840|PMID:17292493|PMID:19139269|PMID:19502594|PMID:19699254|PMID:19846903|PMID:22226932 |
Tp53 | Rat | carbachol | multiple interactions | ISO | RGD:11440 | 6480464 | Carbachol inhibits the reaction [APP protein modified form results in increased expression of TRP53 protein] | CTD | PMID:10758335 |
Tp53 | Rat | carbamate ester | multiple interactions | ISO | RGD:70502 | 6480464 | Carbamates analog promotes the reaction [ATM protein results in increased phosphorylation of and results in more ... | CTD | PMID:19376255 |
Tp53 | Rat | carbamate ester | increases phosphorylation | ISO | RGD:11440 | 6480464 | Carbamates analog results in increased phosphorylation of TRP53 protein | CTD | PMID:19197993 |
Tp53 | Rat | carbamate ester | affects expression | ISO | RGD:11440 | 6480464 | Carbamates affects the expression of TRP53 protein | CTD | PMID:21303328 |
Tp53 | Rat | carbamazepine | affects expression | ISO | RGD:70502 | 6480464 | Carbamazepine affects the expression of TP53 mRNA | CTD | PMID:24752500 |
Tp53 | Rat | carbendazim | increases expression | EXP | | 6480464 | carbendazim results in increased expression of TP53 mRNA | CTD | PMID:35513110 |
Tp53 | Rat | carbendazim | affects activity | ISO | RGD:70502 | 6480464 | carbendazim affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | CARBENOXOLONE | affects expression | ISO | RGD:70502 | 6480464 | Carbenoxolone affects the expression of TP53 mRNA | CTD | PMID:23678415 |
Tp53 | Rat | carbofuran | multiple interactions | ISO | RGD:70502 | 6480464 | Carbofuran results in decreased stability of and results in increased degradation of and results in more ... | CTD | PMID:22445671 |
Tp53 | Rat | carbon nanotube | multiple interactions | ISO | RGD:70502 | 6480464 | Nanotubes, Carbon results in decreased expression of and results in increased phosphorylation of TP53 protein | CTD | PMID:23634900 |
Tp53 | Rat | carbon nanotube | increases expression | ISO | RGD:11440 | 6480464 | Nanotubes, Carbon analog results in increased expression of TRP53 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681 |
Tp53 | Rat | carbon nanotube | decreases expression | ISO | RGD:70502 | 6480464 | Nanotubes, Carbon results in decreased expression of TP53 mRNA | CTD | PMID:15585362 |
Tp53 | Rat | Carbophenothion | affects activity | ISO | RGD:70502 | 6480464 | carbophenothion metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | carboplatin | increases expression | ISO | RGD:70502 | 6480464 | Carboplatin results in increased expression of TP53 mRNA; Carboplatin results in increased expression of TP53 more ... | CTD | PMID:15131059|PMID:33002289|PMID:9664115 |
Tp53 | Rat | carboplatin | multiple interactions | ISO | RGD:70502 | 6480464 | [Carboplatin co-treated with Gallic Acid] results in increased expression of TP53 protein; [Gallic Acid co-treated more ... | CTD | PMID:33002289 |
Tp53 | Rat | carfilzomib | increases activity | ISO | RGD:70502 | 6480464 | carfilzomib results in increased activity of TP53 protein | CTD | PMID:30818834 |
Tp53 | Rat | carfilzomib | affects activity | ISO | RGD:70502 | 6480464 | carfilzomib affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Carmofur | affects activity | ISO | RGD:70502 | 6480464 | carmofur affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | carmustine | increases expression | ISO | RGD:70502 | 6480464 | Carmustine results in increased expression of TP53 protein | CTD | PMID:15735757|PMID:16193384|PMID:18632648 |
Tp53 | Rat | carmustine | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 results in increased susceptibility to Carmustine | CTD | PMID:10455409 |
Tp53 | Rat | carmustine | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in decreased susceptibility to Carmustine | CTD | PMID:16193384 |
Tp53 | Rat | carmustine | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein modified form affects the susceptibility to Carmustine | CTD | PMID:11861384 |
Tp53 | Rat | carmustine | multiple interactions | ISO | RGD:70502 | 6480464 | [Carmustine co-treated with O(6)-benzylguanine] results in increased expression of TP53 protein; MDM4 protein promotes the more ... | CTD | PMID:15735757|PMID:20472715 |
Tp53 | Rat | carteolol | affects expression | ISO | RGD:70502 | 6480464 | Carteolol affects the expression of TP53 mRNA | CTD | PMID:37120125 |
Tp53 | Rat | carvedilol | affects expression | EXP | | 6480464 | carvedilol affects the expression of TP53 protein | CTD | PMID:22000973 |
Tp53 | Rat | carvedilol | multiple interactions | EXP | | 6480464 | carvedilol inhibits the reaction [Potassium Dichromate results in increased expression of TP53 protein] | CTD | PMID:25245570 |
Tp53 | Rat | casticin | increases expression | ISO | RGD:70502 | 6480464 | casticin results in increased expression of TP53 protein modified form | CTD | PMID:29098808 |
Tp53 | Rat | casticin | decreases expression | ISO | RGD:70502 | 6480464 | casticin results in decreased expression of TP53 protein | CTD | PMID:29098808 |
Tp53 | Rat | cefalotin | increases expression | ISO | RGD:70502 | 6480464 | Cephalothin results in increased expression of TP53 protein | CTD | PMID:15012731 |
Tp53 | Rat | cefotaxime | increases expression | ISO | RGD:70502 | 6480464 | Cefotaxime results in increased expression of TP53 protein | CTD | PMID:15012731 |
Tp53 | Rat | celastrol | increases expression | ISO | RGD:70502 | 6480464 | celastrol results in increased expression of TP53 protein | CTD | PMID:27374097 |
Tp53 | Rat | celastrol | multiple interactions | ISO | RGD:70502 | 6480464 | Uridine inhibits the reaction [celastrol results in increased expression of TP53 protein] | CTD | PMID:27374097 |
Tp53 | Rat | celecoxib | increases expression | ISO | RGD:70502 | 6480464 | Celecoxib results in increased expression of TP53 mRNA; Celecoxib results in increased expression of TP53 more ... | CTD | PMID:18202791|PMID:19706164 |
Tp53 | Rat | celecoxib | multiple interactions | EXP | | 6480464 | Celecoxib inhibits the reaction [Gentamicins results in increased expression of TP53 protein] | CTD | PMID:31628940 |
Tp53 | Rat | celecoxib | multiple interactions | ISO | RGD:11440 | 6480464 | [Celecoxib co-treated with docetaxel] results in increased expression of TRP53 protein; Celecoxib promotes the reaction more ... | CTD | PMID:15458769|PMID:16052515 |
Tp53 | Rat | celecoxib | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 results in increased susceptibility to Celecoxib | CTD | PMID:19706164 |
Tp53 | Rat | celecoxib | multiple interactions | ISO | RGD:70502 | 6480464 | [FEC protocol co-treated with Celecoxib] results in decreased expression of TP53 protein; Celecoxib results in more ... | CTD | PMID:16507397|PMID:18760266|PMID:19706164 |
Tp53 | Rat | cepharanthine | increases expression | ISO | RGD:70502 | 6480464 | cepharanthine results in increased expression of TP53 protein | CTD | PMID:31255635 |
Tp53 | Rat | ceric oxide | increases phosphorylation | ISO | RGD:70502 | 6480464 | ceric oxide results in increased phosphorylation of TP53 protein | CTD | PMID:24987704 |
Tp53 | Rat | ceric oxide | multiple interactions | ISO | RGD:70502 | 6480464 | [Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in more ... | CTD | PMID:36982514 |
Tp53 | Rat | cerium | decreases expression | ISO | RGD:70502 | 6480464 | Cerium results in decreased expression of TP53 mRNA | CTD | PMID:35641671 |
Tp53 | Rat | cetrorelix | increases expression | ISO | RGD:70502 | 6480464 | cetrorelix results in increased expression of TP53 protein | CTD | PMID:21062912 |
Tp53 | Rat | CGS-21680 | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TP53 more ... | CTD | PMID:30555576 |
Tp53 | Rat | chalcones | increases expression | ISO | RGD:70502 | 6480464 | Chalcones analog results in increased expression of TP53 mRNA | CTD | PMID:32856275 |
Tp53 | Rat | chlorambucil | increases expression | ISO | RGD:70502 | 6480464 | Chlorambucil results in increased expression of TP53; Chlorambucil results in increased expression of TP53 protein | CTD | PMID:18092340|PMID:8822937 |
Tp53 | Rat | chlorambucil | affects activity | ISO | RGD:70502 | 6480464 | Chlorambucil affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | chlorambucil | multiple interactions | ISO | RGD:70502 | 6480464 | [Theophylline co-treated with Chlorambucil] results in increased expression of TP53; IL4 protein inhibits the reaction more ... | CTD | PMID:8822937 |
Tp53 | Rat | chlorfenvinfos | affects activity | ISO | RGD:70502 | 6480464 | Chlorfenvinphos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | chloroacetaldehyde | affects activity | ISO | RGD:70502 | 6480464 | chloroacetaldehyde affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | chloroethene | multiple interactions | ISO | RGD:70502 | 6480464 | CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]; CYP2E1 more ... | CTD | PMID:12010862|PMID:12705718|PMID:14602524|PMID:16097394|PMID:16881598|PMID:17384900 |
Tp53 | Rat | chloroethene | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 polymorphism affects the susceptibility to Vinyl Chloride | CTD | PMID:24464562 |
Tp53 | Rat | chloroethene | decreases expression | ISO | RGD:70502 | 6480464 | Vinyl Chloride results in decreased expression of TP53 mRNA | CTD | PMID:22076037 |
Tp53 | Rat | chloroethene | increases expression | ISO | RGD:70502 | 6480464 | Vinyl Chloride results in increased expression of TP53 protein; Vinyl Chloride results in increased expression more ... | CTD | PMID:12670519|PMID:14979067|PMID:16474264 |
Tp53 | Rat | chloroethene | increases mutagenesis | ISO | RGD:70502 | 6480464 | Vinyl Chloride results in increased mutagenesis of TP53 gene | CTD | PMID:12010862|PMID:12670519|PMID:16881598|PMID:17384900 |
Tp53 | Rat | chloroethene | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene SNP results in increased susceptibility to Vinyl Chloride | CTD | PMID:18226366 |
Tp53 | Rat | chloroform | increases expression | EXP | | 6480464 | Chloroform results in increased expression of TP53 mRNA | CTD | PMID:17522070 |
Tp53 | Rat | chloroform | increases phosphorylation | EXP | | 6480464 | Chloroform results in increased phosphorylation of TP53 protein | CTD | PMID:8076368 |
Tp53 | Rat | chloroform | increases phosphorylation | ISO | RGD:70502 | 6480464 | Chloroform results in increased phosphorylation of TP53 protein | CTD | PMID:8076368 |
Tp53 | Rat | chlorogenic acid | multiple interactions | ISO | RGD:11440 | 6480464 | Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of TRP53 protein] | CTD | PMID:25043994 |
Tp53 | Rat | chlorogenic acid | increases expression | ISO | RGD:11440 | 6480464 | Chlorogenic Acid results in increased expression of TRP53 mRNA | CTD | PMID:33058431 |
Tp53 | Rat | chlorophyllin | multiple interactions | ISO | RGD:11440 | 6480464 | chlorophyllin inhibits the reaction [titanium dioxide results in increased mutagenesis of TRP53 exon] | CTD | PMID:25129858 |
Tp53 | Rat | chlorophyllin | multiple interactions | EXP | | 6480464 | chlorophyllin inhibits the reaction [Cyclophosphamide results in increased mutagenesis of TP53 exon] | CTD | PMID:19227835 |
Tp53 | Rat | chloropicrin | increases expression | ISO | RGD:70502 | 6480464 | chloropicrin results in increased expression of TP53 protein | CTD | PMID:22516760|PMID:24548678 |
Tp53 | Rat | chloropicrin | increases phosphorylation | ISO | RGD:70502 | 6480464 | chloropicrin results in increased phosphorylation of TP53 protein | CTD | PMID:31884112 |
Tp53 | Rat | chloroquine | increases activity | ISO | RGD:70502 | 6480464 | Chloroquine results in increased activity of TP53; Chloroquine results in increased activity of TP53 protein | CTD | PMID:12082016|PMID:18089834 |
Tp53 | Rat | chloroquine | multiple interactions | ISO | RGD:70502 | 6480464 | Chloroquine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein] | CTD | PMID:22927544 |
Tp53 | Rat | chloroquine | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 mutant form inhibits the reaction [Chloroquine results in increased activity of CASP3 protein] | CTD | PMID:11589424 |
Tp53 | Rat | chlorpromazine | affects activity | EXP | | 6480464 | Chlorpromazine affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of TP53 mRNA | CTD | PMID:12464398|PMID:17452286 |
Tp53 | Rat | chlorpyrifos | affects activity | ISO | RGD:70502 | 6480464 | Chlorpyrifos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | chlorpyrifos | affects expression | ISO | RGD:11440 | 6480464 | Chlorpyrifos affects the expression of TRP53 mRNA | CTD | PMID:30378422 |
Tp53 | Rat | chlorpyrifos | decreases expression | ISO | RGD:11440 | 6480464 | Chlorpyrifos results in decreased expression of TRP53 mRNA | CTD | PMID:30378422 |
Tp53 | Rat | chlorpyrifos | multiple interactions | ISO | RGD:11440 | 6480464 | BBC3 gene mutant form inhibits the reaction [Chlorpyrifos results in increased expression of TRP53 mRNA]; more ... | CTD | PMID:32120800|PMID:34289071 |
Tp53 | Rat | chlorpyrifos | increases expression | ISO | RGD:11440 | 6480464 | Chlorpyrifos results in increased expression of TRP53 mRNA; Chlorpyrifos results in increased expression of TRP53 more ... | CTD | PMID:32120800|PMID:34289071 |
Tp53 | Rat | chlorpyrifos | increases expression | ISO | RGD:70502 | 6480464 | Chlorpyrifos results in increased expression of TP53 mRNA | CTD | PMID:30981936 |
Tp53 | Rat | chlorpyrifos | decreases expression | ISO | RGD:70502 | 6480464 | Chlorpyrifos results in decreased expression of TP53 protein | CTD | PMID:27993609 |
Tp53 | Rat | chlorpyrifos | multiple interactions | ISO | RGD:70502 | 6480464 | [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to more ... | CTD | PMID:27993609|PMID:32800223 |
Tp53 | Rat | chlorpyrifos-methyl | affects activity | ISO | RGD:70502 | 6480464 | chlorpyrifos-methyl metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | cholesterol | multiple interactions | ISO | RGD:70502 | 6480464 | [[[EGF protein binds to 1,2-dioleoyl-3-phosphoethanolamine-n-(poly(ethyleneglycol))-hydroxy succinamide] co-treated with [1,2-distearoyllecithin co-treated with Cholesterol co-treated with 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene more ... | CTD | PMID:35385781 |
Tp53 | Rat | choline | decreases expression | EXP | | 6480464 | Choline results in decreased expression of TP53 mRNA | CTD | PMID:16014740 |
Tp53 | Rat | choline | decreases expression | ISO | RGD:11440 | 6480464 | Choline results in decreased expression of TRP53 mRNA | CTD | PMID:16014740 |
Tp53 | Rat | chromium atom | multiple interactions | ISO | RGD:70502 | 6480464 | CDKN1A affects the reaction [Chromium results in increased expression of TP53 protein]; Chromium promotes the more ... | CTD | PMID:18024214|PMID:18602874 |
Tp53 | Rat | chromium atom | increases expression | ISO | RGD:70502 | 6480464 | Chromium results in increased expression of TP53 protein | CTD | PMID:18024214 |
Tp53 | Rat | chromium(6+) | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein results in increased susceptibility to chromium hexavalent ion | CTD | PMID:12324196 |
Tp53 | Rat | chromium(6+) | multiple interactions | EXP | | 6480464 | [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide co-treated with [Potassium Dichromate results in increased abundance of chromium hexavalent ion]] results in more ... | CTD | PMID:35307491 |
Tp53 | Rat | chromium(6+) | multiple interactions | ISO | RGD:11440 | 6480464 | [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation more ... | CTD | PMID:35643323 |
Tp53 | Rat | chromium(6+) | increases expression | EXP | | 6480464 | chromium hexavalent ion results in increased expression of TP53 protein | CTD | PMID:24530425|PMID:32679048 |
Tp53 | Rat | chromium(6+) | increases stability | ISO | RGD:70502 | 6480464 | chromium hexavalent ion results in increased stability of TP53 protein | CTD | PMID:31388677 |
Tp53 | Rat | chromium(6+) | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to chromium hexavalent ion | CTD | PMID:10574974|PMID:16166740 |
Tp53 | Rat | chromium(6+) | increases expression | ISO | RGD:70502 | 6480464 | chromium hexavalent ion results in increased expression of TP53 mRNA; chromium hexavalent ion results in more ... | CTD | PMID:10788560|PMID:16166740|PMID:27793765|PMID:29069462 |
Tp53 | Rat | chromium(6+) | multiple interactions | ISO | RGD:70502 | 6480464 | [chromium hexavalent ion binds to TP53 gene] which results in increased mutagenesis of TP53 gene; more ... | CTD | PMID:14971653|PMID:15831465|PMID:16166740|PMID:22791815|PMID:22886373|PMID:31388677 |
Tp53 | Rat | chromium(6+) | affects binding | ISO | RGD:70502 | 6480464 | chromium hexavalent ion binds to TP53 gene | CTD | PMID:22791815 |
Tp53 | Rat | chromium(6+) | increases activity | ISO | RGD:70502 | 6480464 | chromium hexavalent ion results in increased activity of TP53 protein | CTD | PMID:10574974 |
Tp53 | Rat | chromium(6+) | increases mutagenesis | ISO | RGD:70502 | 6480464 | chromium hexavalent ion results in increased mutagenesis of TP53 gene | CTD | PMID:22791815 |
Tp53 | Rat | chromium(6+) | decreases expression | ISO | RGD:70502 | 6480464 | chromium hexavalent ion results in decreased expression of TP53 protein | CTD | PMID:22666341 |
Tp53 | Rat | chrysene | multiple interactions | ISO | RGD:11440 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... | CTD | PMID:22120587|PMID:27858113 |
Tp53 | Rat | chrysene | increases expression | ISO | RGD:11440 | 6480464 | chrysene results in increased expression of TRP53 protein | CTD | PMID:22120587 |
Tp53 | Rat | chrysin | increases degradation | ISO | RGD:70502 | 6480464 | chrysin results in increased degradation of TP53 protein | CTD | PMID:14634213 |
Tp53 | Rat | chrysin | affects activity | ISO | RGD:70502 | 6480464 | chrysin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | chrysin | multiple interactions | ISO | RGD:70502 | 6480464 | [Cisplatin co-treated with chrysin] affects the localization of TP53 protein; [Cisplatin co-treated with chrysin] results more ... | CTD | PMID:25770930 |
Tp53 | Rat | chrysin | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with chrysin] results in increased expression of TP53 protein; chrysin inhibits the reaction more ... | CTD | PMID:21167192|PMID:29247772 |
Tp53 | Rat | chrysin 5,7-dimethyl ether | multiple interactions | EXP | | 6480464 | [5,7-dimethoxyflavone co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA; [5,7-dimethoxyflavone co-treated with Diethylnitrosamine] more ... | CTD | PMID:21554863 |
Tp53 | Rat | ciclopirox | affects activity | ISO | RGD:70502 | 6480464 | Ciclopirox affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | cidofovir anhydrous | increases expression | ISO | RGD:70502 | 6480464 | Cidofovir results in increased expression of TP53 protein | CTD | PMID:11697818 |
Tp53 | Rat | cidofovir anhydrous | affects activity | ISO | RGD:70502 | 6480464 | Cidofovir affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | cilostazol | increases expression | ISO | RGD:70502 | 6480464 | cilostazol results in increased expression of TP53 protein | CTD | PMID:10642304 |
Tp53 | Rat | cilostazol | multiple interactions | EXP | | 6480464 | cilostazol inhibits the reaction [Nitroprusside results in increased phosphorylation of TP53 protein] | CTD | PMID:18311796 |
Tp53 | Rat | Cirsimarin | decreases expression | ISO | RGD:70502 | 6480464 | cirsimarin results in decreased expression of TP53 mRNA | CTD | PMID:35710092 |
Tp53 | Rat | cis-caffeic acid | affects expression | ISO | RGD:70502 | 6480464 | caffeic acid affects the expression of TP53 protein | CTD | PMID:11522280 |
Tp53 | Rat | cis-caffeic acid | multiple interactions | ISO | RGD:70502 | 6480464 | caffeic acid promotes the reaction [Thapsigargin results in decreased expression of TP53 mRNA] | CTD | PMID:19442820 |
Tp53 | Rat | cisplatin | increases expression | ISO | RGD:11440 | 6480464 | Cisplatin results in increased expression of TRP53; Cisplatin results in increased expression of TRP53 mRNA; more ... | CTD | PMID:18558085|PMID:19428948|PMID:20510337|PMID:20702592|PMID:20883750|PMID:21552291|PMID:22269388|PMID:23770416|PMID:25043994|PMID:25308879|PMID:26768586|PMID:28119452|PMID:35842499|PMID:38688426 |
Tp53 | Rat | cisplatin | increases stability | ISO | RGD:70502 | 6480464 | Cisplatin results in increased stability of TP53 protein | CTD | PMID:32238696 |
Tp53 | Rat | cisplatin | affects activity | ISO | RGD:70502 | 6480464 | Cisplatin affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | cisplatin | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Cisplatin | CTD | PMID:12185594|PMID:17670903|PMID:20477944 |
Tp53 | Rat | cisplatin | affects localization | ISO | RGD:11440 | 6480464 | Cisplatin affects the localization of TRP53 protein; Cisplatin affects the localization of TRP53 protein modified more ... | CTD | PMID:24560772|PMID:26193055 |
Tp53 | Rat | cisplatin | increases phosphorylation | EXP | | 6480464 | Cisplatin results in increased phosphorylation of TP53 protein | CTD | PMID:33393703 |
Tp53 | Rat | cisplatin | increases phosphorylation | ISO | RGD:70502 | 6480464 | Cisplatin results in increased phosphorylation of TP53 protein | CTD | PMID:20145152|PMID:21285353|PMID:21532991|PMID:21552291|PMID:21660965|PMID:21801448|PMID:29944906 |
Tp53 | Rat | cisplatin | decreases expression | ISO | RGD:11440 | 6480464 | Cisplatin results in decreased expression of TRP53 protein | CTD | PMID:20566416 |
Tp53 | Rat | cisplatin | increases response to substance | EXP | | 6480464 | TP53 protein results in increased susceptibility to Cisplatin | CTD | PMID:15315938 |
Tp53 | Rat | cisplatin | multiple interactions | EXP | | 6480464 | [epigallocatechin gallate co-treated with coenzyme Q10] inhibits the reaction [Cisplatin results in increased phosphorylation of more ... | CTD | PMID:15315938|PMID:18310471|PMID:20650967|PMID:25184746|PMID:25640527|PMID:26120027|PMID:26612654|PMID:26739623|PMID:28119452|PMID:28414026|PMID:29852128|PMID:33393703|PMID:35842499|PMID:36567042 |
Tp53 | Rat | cisplatin | increases acetylation | EXP | | 6480464 | Cisplatin results in increased acetylation of TP53 protein | CTD | PMID:21416250 |
Tp53 | Rat | cisplatin | increases phosphorylation | ISO | RGD:11440 | 6480464 | Cisplatin results in increased phosphorylation of TP53 protein; Cisplatin results in increased phosphorylation of TRP53 more ... | CTD | PMID:20883750|PMID:21151649|PMID:21285353|PMID:21552291|PMID:21633170|PMID:26193055|PMID:31256211 |
Tp53 | Rat | cisplatin | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Cisplatin; TP53 protein modified form affects the susceptibility to more ... | CTD | PMID:11861384|PMID:22331493|PMID:32238696 |
Tp53 | Rat | cisplatin | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 mutant form results in increased susceptibility to Cisplatin; TP53 protein results in increased susceptibility more ... | CTD | PMID:16193384|PMID:16211088|PMID:19548002|PMID:21258400|PMID:21447800|PMID:21532991|PMID:21552291|PMID:21875941|PMID:29471073 |
Tp53 | Rat | cisplatin | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in decreased susceptibility to Cisplatin; TP53 protein results in decreased more ... | CTD | PMID:15578696|PMID:15990222|PMID:16020667 |
Tp53 | Rat | cisplatin | increases glutathionylation | ISO | RGD:70502 | 6480464 | Cisplatin results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | cisplatin | increases localization | ISO | RGD:70502 | 6480464 | Cisplatin results in increased localization of TP53 protein; Cisplatin results in increased localization of TP53 more ... | CTD | PMID:21109480 |
Tp53 | Rat | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of TP53 mRNA; Cisplatin results in increased expression of TP53 more ... | CTD | PMID:20650967|PMID:25184746|PMID:25640527|PMID:26120027|PMID:26612654|PMID:26739623|PMID:28119452|PMID:28414026|PMID:29852128|PMID:35842499|PMID:36567042 |
Tp53 | Rat | cisplatin | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein results in increased susceptibility to Cisplatin | CTD | PMID:21552291 |
Tp53 | Rat | cisplatin | increases expression | ISO | RGD:70502 | 6480464 | Cisplatin results in increased expression of TP53; Cisplatin results in increased expression of TP53 mRNA; more ... | CTD | PMID:12082016|PMID:15454482|PMID:15496615|PMID:15990222|PMID:16193384|PMID:16601104|PMID:16797627|PMID:17555331|PMID:19144690|PMID:20100536|PMID:20477830|PMID:20514524|PMID:20623183|PMID:20674069|PMID:20878077|PMID:21109480|PMID:21216935|PMID:21274007|PMID:21356574|PMID:21429301|PMID:21532991|PMID:21552291|PMID:21624110|PMID:21696631|PMID:21742020|PMID:21858171|PMID:21880462|PMID:23300844|PMID:25776512|PMID:26961604|PMID:27358234|PMID:29471006|PMID:29471073|PMID:29690507|PMID:29962303|PMID:34126102|PMID:9664115 |
Tp53 | Rat | cisplatin | increases acetylation | ISO | RGD:70502 | 6480464 | Cisplatin results in increased acetylation of TP53 protein | CTD | PMID:21532991 |
Tp53 | Rat | cisplatin | decreases phosphorylation | ISO | RGD:70502 | 6480464 | Cisplatin results in decreased phosphorylation of TP53 protein | CTD | PMID:15854392 |
Tp53 | Rat | cisplatin | increases acetylation | ISO | RGD:11440 | 6480464 | Cisplatin results in increased acetylation of TRP53 protein | CTD | PMID:21593185 |
Tp53 | Rat | cisplatin | affects localization | ISO | RGD:70502 | 6480464 | Cisplatin affects the localization of TP53 protein | CTD | PMID:21858171 |
Tp53 | Rat | cisplatin | multiple interactions | ISO | RGD:70502 | 6480464 | 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one promotes the reaction [Cisplatin results in increased localization of TP53 protein mutant form]; [[Chlorpyrifos more ... | CTD | PMID:12807743|PMID:14562046|PMID:15254702|PMID:15496615|PMID:15999354|PMID:16077963|PMID:16601104|PMID:17216584|PMID:17498666|PMID:17555331|PMID:19548002|PMID:20145152|PMID:20514524|PMID:20623183|PMID:20674069|PMID:20878077|PMID:21109480|PMID:21152876|PMID:21205074|PMID:21216935|PMID:21258400|PMID:21285353|PMID:21429301|PMID:21489314|PMID:21489989|PMID:21509038|PMID:21532991|PMID:21552291|PMID:21624110|PMID:21660965|PMID:21696631|PMID:21742020|PMID:21858171|PMID:21875941|PMID:22269388|PMID:22331493|PMID:24799992|PMID:25770930|PMID:27514524|PMID:28371273|PMID:29471006|PMID:29471073|PMID:29690507|PMID:29944906|PMID:29962303|PMID:30871063|PMID:32238696|PMID:32800223|PMID:33520990|PMID:34126102|PMID:34822033 |
Tp53 | Rat | cisplatin | multiple interactions | ISO | RGD:11440 | 6480464 | 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Cisplatin results in increased expression of TRP53 protein]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the more ... | CTD | PMID:15983031|PMID:17670903|PMID:18558085|PMID:20510337|PMID:20702592|PMID:21285353|PMID:21552291|PMID:21593185|PMID:22003191|PMID:22269388|PMID:23770416|PMID:24560772|PMID:25043994|PMID:25308879|PMID:26193055|PMID:26768586|PMID:28119452|PMID:31256211|PMID:34089817|PMID:35842499|PMID:38688426 |
Tp53 | Rat | cladribine | affects activity | ISO | RGD:70502 | 6480464 | Cladribine affects the activity of TP53 protein; Cladribine metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | clodronic acid | affects activity | ISO | RGD:70502 | 6480464 | Clodronic Acid affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | clofarabine | multiple interactions | ISO | RGD:70502 | 6480464 | [resveratrol co-treated with clofarabine] affects the localization of TP53 protein modified form; [resveratrol co-treated with more ... | CTD | PMID:24239893 |
Tp53 | Rat | clofarabine | affects activity | ISO | RGD:70502 | 6480464 | Clofarabine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of TP53 mRNA | CTD | PMID:17602206 |
Tp53 | Rat | clofibric acid | affects expression | EXP | | 6480464 | Clofibric Acid affects the expression of TP53 mRNA | CTD | PMID:17602206 |
Tp53 | Rat | clopidogrel | increases expression | ISO | RGD:70502 | 6480464 | clopidogrel results in increased expression of TP53 mRNA; clopidogrel results in increased expression of TP53 more ... | CTD | PMID:9447704 |
Tp53 | Rat | clotrimazole | increases expression | ISO | RGD:70502 | 6480464 | Clotrimazole results in increased expression of TP53 protein | CTD | PMID:10223459 |
Tp53 | Rat | clozapine | increases expression | ISO | RGD:70502 | 6480464 | Clozapine results in increased expression of TP53 mRNA | CTD | PMID:16160616 |
Tp53 | Rat | clozapine | multiple interactions | ISO | RGD:70502 | 6480464 | CSF3 protein inhibits the reaction [Clozapine results in increased expression of TP53 mRNA] | CTD | PMID:16160616 |
Tp53 | Rat | cobalt atom | increases expression | ISO | RGD:70502 | 6480464 | Cobalt results in increased expression of TP53 protein | CTD | PMID:21598295 |
Tp53 | Rat | cobalt atom | multiple interactions | ISO | RGD:70502 | 6480464 | [tungsten carbide co-treated with Cobalt] results in increased expression of and results in increased stability more ... | CTD | PMID:23052192|PMID:24068677 |
Tp53 | Rat | cobalt dichloride | multiple interactions | ISO | RGD:70502 | 6480464 | 3-methyladenine inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased more ... | CTD | PMID:10951577|PMID:16527254|PMID:19714248|PMID:21687937|PMID:22269387|PMID:23380477|PMID:25446071|PMID:30381462 |
Tp53 | Rat | cobalt dichloride | increases stability | ISO | RGD:70502 | 6480464 | cobaltous chloride results in increased stability of TP53 protein | CTD | PMID:30381462 |
Tp53 | Rat | cobalt dichloride | increases expression | ISO | RGD:11440 | 6480464 | cobaltous chloride results in increased expression of TRP53 mRNA | CTD | PMID:24265542 |
Tp53 | Rat | cobalt dichloride | multiple interactions | ISO | RGD:11440 | 6480464 | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole promotes the reaction [cobaltous chloride results in increased expression of TRP53 mRNA] | CTD | PMID:24265542 |
Tp53 | Rat | cobalt dichloride | decreases activity | ISO | RGD:70502 | 6480464 | cobaltous chloride results in decreased activity of TP53 protein | CTD | PMID:25446071 |
Tp53 | Rat | cobalt dichloride | increases expression | ISO | RGD:70502 | 6480464 | cobaltous chloride results in increased expression of TP53 mRNA; cobaltous chloride results in increased expression more ... | CTD | PMID:20974702|PMID:22269387|PMID:23380477 |
Tp53 | Rat | cobalt dichloride | decreases expression | ISO | RGD:11440 | 6480464 | cobaltous chloride results in decreased expression of TRP53 mRNA | CTD | PMID:16772336 |
Tp53 | Rat | cobalt dichloride | multiple interactions | EXP | | 6480464 | cobaltous chloride promotes the reaction [Diethylnitrosamine results in increased expression of TP53 protein] | CTD | PMID:11751435 |
Tp53 | Rat | cocaine | affects expression | ISO | RGD:11440 | 6480464 | Cocaine affects the expression of TRP53 mRNA | CTD | PMID:15681117 |
Tp53 | Rat | coenzyme Q10 | multiple interactions | ISO | RGD:11440 | 6480464 | coenzyme Q10 inhibits the reaction [Cisplatin results in increased expression of TRP53 protein] | CTD | PMID:20510337 |
Tp53 | Rat | coenzyme Q10 | multiple interactions | EXP | | 6480464 | [epigallocatechin gallate co-treated with coenzyme Q10] inhibits the reaction [Cisplatin results in increased phosphorylation of more ... | CTD | PMID:33393703 |
Tp53 | Rat | colforsin daropate hydrochloride | increases expression | ISO | RGD:70502 | 6480464 | Colforsin results in increased expression of TP53 protein | CTD | PMID:10642304 |
Tp53 | Rat | colistin | increases expression | EXP | | 6480464 | Colistin results in increased expression of TP53 protein | CTD | PMID:28842171 |
Tp53 | Rat | colistin | multiple interactions | EXP | | 6480464 | Anisomycin promotes the reaction [Colistin results in increased expression of TP53 protein]; pyrazolanthrone inhibits the more ... | CTD | PMID:28842171 |
Tp53 | Rat | conjugated linoleic acid | increases expression | ISO | RGD:70502 | 6480464 | Linoleic Acids, Conjugated results in increased expression of TP53 protein | CTD | PMID:15961301 |
Tp53 | Rat | copper atom | multiple interactions | ISO | RGD:70502 | 6480464 | [2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene; more ... | CTD | PMID:10334203|PMID:11275476|PMID:11964141|PMID:15880691|PMID:16391388|PMID:17327230|PMID:20931265|PMID:30911355 |
Tp53 | Rat | copper atom | increases expression | ISO | RGD:70502 | 6480464 | Copper results in increased expression of TP53 protein | CTD | PMID:15880691|PMID:20875833 |
Tp53 | Rat | copper atom | increases oxidation | ISO | RGD:70502 | 6480464 | Copper results in increased oxidation of TP53 protein | CTD | PMID:11964141 |
Tp53 | Rat | copper atom | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Copper | CTD | PMID:15880691 |
Tp53 | Rat | copper atom | decreases activity | ISO | RGD:70502 | 6480464 | Copper results in decreased activity of TP53 protein | CTD | PMID:16246896 |
Tp53 | Rat | copper atom | multiple interactions | EXP | | 6480464 | [Copper deficiency co-treated with tetrathiomolybdate] results in increased expression of TP53 protein; [Copper Sulfate results more ... | CTD | PMID:22276220|PMID:34577062 |
Tp53 | Rat | copper(0) | multiple interactions | ISO | RGD:70502 | 6480464 | [2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene; more ... | CTD | PMID:10334203|PMID:11275476|PMID:11964141|PMID:15880691|PMID:16391388|PMID:17327230|PMID:20931265|PMID:30911355 |
Tp53 | Rat | copper(0) | increases expression | ISO | RGD:70502 | 6480464 | Copper results in increased expression of TP53 protein | CTD | PMID:15880691|PMID:20875833 |
Tp53 | Rat | copper(0) | increases oxidation | ISO | RGD:70502 | 6480464 | Copper results in increased oxidation of TP53 protein | CTD | PMID:11964141 |
Tp53 | Rat | copper(0) | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Copper | CTD | PMID:15880691 |
Tp53 | Rat | copper(0) | decreases activity | ISO | RGD:70502 | 6480464 | Copper results in decreased activity of TP53 protein | CTD | PMID:16246896 |
Tp53 | Rat | copper(0) | multiple interactions | EXP | | 6480464 | [Copper deficiency co-treated with tetrathiomolybdate] results in increased expression of TP53 protein; [Copper Sulfate results more ... | CTD | PMID:22276220|PMID:34577062 |
Tp53 | Rat | copper(II) chloride | increases expression | ISO | RGD:11440 | 6480464 | cupric chloride results in increased expression of TRP53 protein | CTD | PMID:23313662 |
Tp53 | Rat | copper(II) chloride | decreases expression | ISO | RGD:70502 | 6480464 | cupric chloride results in decreased expression of TP53 mRNA | CTD | PMID:38568856 |
Tp53 | Rat | copper(II) chloride | multiple interactions | ISO | RGD:70502 | 6480464 | [cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein; CAT protein inhibits more ... | CTD | PMID:29803612 |
Tp53 | Rat | copper(II) chloride | decreases expression | ISO | RGD:11440 | 6480464 | cupric chloride results in decreased expression of TRP53 protein | CTD | PMID:24170445 |
Tp53 | Rat | copper(II) chloride | affects expression | ISO | RGD:11440 | 6480464 | cupric chloride affects the expression of TRP53 mRNA | CTD | PMID:23313662 |
Tp53 | Rat | copper(II) sulfate | multiple interactions | ISO | RGD:70502 | 6480464 | Copper Sulfate results in increased phosphorylation of and results in increased expression of TP53 protein | CTD | PMID:15001399 |
Tp53 | Rat | copper(II) sulfate | multiple interactions | EXP | | 6480464 | [Copper Sulfate results in increased abundance of Copper] which results in increased expression of TP53 more ... | CTD | PMID:34577062 |
Tp53 | Rat | copper(II) sulfate | decreases expression | ISO | RGD:70502 | 6480464 | Copper Sulfate results in decreased expression of TP53 mRNA | CTD | PMID:27825931 |
Tp53 | Rat | copper(II) sulfate | increases expression | ISO | RGD:11440 | 6480464 | Copper Sulfate results in increased expression of TRP53 mRNA | CTD | PMID:25216733 |
Tp53 | Rat | cordycepin | multiple interactions | EXP | | 6480464 | ADORA2A mutant form inhibits the reaction [cordycepin results in increased phosphorylation of and results in more ... | CTD | PMID:23690541|PMID:24704558 |
Tp53 | Rat | cordycepin | multiple interactions | ISO | RGD:70502 | 6480464 | [Cisplatin co-treated with cordycepin] results in increased phosphorylation of TP53 protein | CTD | PMID:33520990 |
Tp53 | Rat | cordycepin | affects expression | ISO | RGD:70502 | 6480464 | cordycepin affects the expression of TP53 mRNA | CTD | PMID:36881089 |
Tp53 | Rat | cordycepin | increases phosphorylation | ISO | RGD:11440 | 6480464 | cordycepin results in increased phosphorylation of TRP53 protein | CTD | PMID:26303320 |
Tp53 | Rat | cordycepin | increases expression | ISO | RGD:70502 | 6480464 | cordycepin results in increased expression of TP53 mRNA | CTD | PMID:28987792 |
Tp53 | Rat | coumaphos | affects activity | ISO | RGD:70502 | 6480464 | Coumaphos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | coumarin | increases expression | ISO | RGD:70502 | 6480464 | coumarin analog results in increased expression of TP53 mRNA; coumarin analog results in increased expression more ... | CTD | PMID:32578917 |
Tp53 | Rat | coumarin 460 | affects activity | ISO | RGD:70502 | 6480464 | 4-methyl-7-diethylaminocoumarin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Crenigacestat | multiple interactions | ISO | RGD:70502 | 6480464 | crenigacestat inhibits the reaction [Homoharringtonine results in increased expression of TP53 protein] | CTD | PMID:31307525 |
Tp53 | Rat | cridanimod | affects activity | ISO | RGD:70502 | 6480464 | 10-carboxymethyl-9-acridanone affects the activity of TP53 protein; 10-carboxymethyl-9-acridanone metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | crocidolite asbestos | multiple interactions | ISO | RGD:70502 | 6480464 | Asbestos, Crocidolite results in decreased expression of and results in increased phosphorylation of TP53 protein; more ... | CTD | PMID:20705543|PMID:23634900 |
Tp53 | Rat | crocidolite asbestos | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Asbestos, Crocidolite | CTD | PMID:9400702 |
Tp53 | Rat | crocidolite asbestos | multiple interactions | ISO | RGD:11440 | 6480464 | OGG1 protein mutant form promotes the reaction [Asbestos, Crocidolite results in increased expression of TRP53 more ... | CTD | PMID:24918270 |
Tp53 | Rat | crocidolite asbestos | increases expression | ISO | RGD:11440 | 6480464 | Asbestos, Crocidolite results in increased expression of TRP53 protein | CTD | PMID:24918270 |
Tp53 | Rat | crocidolite asbestos | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in increased susceptibility to Asbestos, Crocidolite | CTD | PMID:12151629|PMID:18303189 |
Tp53 | Rat | crocidolite asbestos | increases mutagenesis | ISO | RGD:11440 | 6480464 | Asbestos, Crocidolite results in increased mutagenesis of TRP53 exon | CTD | PMID:10992274 |
Tp53 | Rat | crocidolite asbestos | increases phosphorylation | ISO | RGD:70502 | 6480464 | Asbestos, Crocidolite results in increased phosphorylation of TP53 protein | CTD | PMID:12676607 |
Tp53 | Rat | crocidolite asbestos | increases expression | ISO | RGD:70502 | 6480464 | Asbestos, Crocidolite results in increased expression of TP53 protein | CTD | PMID:12676607 |
Tp53 | Rat | crocidolite asbestos | affects expression | ISO | RGD:70502 | 6480464 | Asbestos, Crocidolite affects the expression of TP53 mRNA; Asbestos, Crocidolite affects the expression of TP53 more ... | CTD | PMID:17331233|PMID:21570478 |
Tp53 | Rat | crocidolite asbestos | decreases expression | ISO | RGD:70502 | 6480464 | Asbestos, Crocidolite results in decreased expression of TP53 protein; Asbestos, Crocidolite results in decreased expression more ... | CTD | PMID:21570478|PMID:23634900 |
Tp53 | Rat | crocin-1 | multiple interactions | ISO | RGD:11440 | 6480464 | crocin inhibits the reaction [Paraquat results in increased expression of TRP53 mRNA]; crocin inhibits the more ... | CTD | PMID:26231423|PMID:31911963 |
Tp53 | Rat | crotonaldehyde | increases expression | EXP | | 6480464 | 2-butenal results in increased expression of TP53 protein | CTD | PMID:23535401 |
Tp53 | Rat | Crufomate | affects activity | ISO | RGD:70502 | 6480464 | crufomate metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | cryptolepine | increases expression | ISO | RGD:70502 | 6480464 | cryptolepine results in increased expression of TP53 protein | CTD | PMID:16120219 |
Tp53 | Rat | cryptolepine | increases activity | ISO | RGD:70502 | 6480464 | cryptolepine results in increased activity of TP53 protein | CTD | PMID:16120219 |
Tp53 | Rat | crystal violet | multiple interactions | ISO | RGD:70502 | 6480464 | Gentian Violet inhibits the reaction [NOX1 protein results in decreased activity of TP53 protein]; Gentian more ... | CTD | PMID:24535435 |
Tp53 | Rat | crystal violet | affects activity | ISO | RGD:70502 | 6480464 | Gentian Violet affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | CU-O LINKAGE | decreases expression | ISO | RGD:70502 | 6480464 | cupric oxide results in decreased expression of TP53 mRNA | CTD | PMID:22077320|PMID:32285662 |
Tp53 | Rat | CU-O LINKAGE | multiple interactions | ISO | RGD:11440 | 6480464 | cupric oxide analog results in decreased phosphorylation of and results in decreased expression of TRP53 more ... | CTD | PMID:25336953 |
Tp53 | Rat | CU-O LINKAGE | multiple interactions | ISO | RGD:70502 | 6480464 | cupric oxide analog results in decreased phosphorylation of and results in decreased expression of TP53 more ... | CTD | PMID:25336953 |
Tp53 | Rat | cudraflavone B | increases expression | ISO | RGD:70502 | 6480464 | cudraflavone B results in increased expression of TP53 protein | CTD | PMID:23881456 |
Tp53 | Rat | cudraflavone B | multiple interactions | ISO | RGD:70502 | 6480464 | resveratrol inhibits the reaction [cudraflavone B results in increased expression of TP53 protein]; sirtinol promotes more ... | CTD | PMID:23881456 |
Tp53 | Rat | Cuprizon | increases expression | ISO | RGD:11440 | 6480464 | Cuprizone results in increased expression of TRP53 mRNA; Cuprizone results in increased expression of TRP53 more ... | CTD | PMID:18550754 |
Tp53 | Rat | Cuprizon | decreases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein mutant form results in decreased susceptibility to Cuprizone | CTD | PMID:18550754 |
Tp53 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of TP53 mRNA | CTD | PMID:26577399|PMID:27523638 |
Tp53 | Rat | curcumin | multiple interactions | ISO | RGD:70502 | 6480464 | [Arsenic Trioxide co-treated with Curcumin] results in increased expression of TP53 protein; [Curcumin co-treated with more ... | CTD | PMID:19020741|PMID:21134073|PMID:23222814|PMID:24664296|PMID:24831732|PMID:27430728|PMID:30935902|PMID:36352148 |
Tp53 | Rat | curcumin | decreases expression | ISO | RGD:70502 | 6480464 | Curcumin analog results in decreased expression of TP53 mRNA; Curcumin results in decreased expression of more ... | CTD | PMID:26409325|PMID:30935902|PMID:33582110 |
Tp53 | Rat | curcumin | decreases expression | ISO | RGD:11440 | 6480464 | Curcumin results in decreased expression of TP53 protein | CTD | PMID:22714040 |
Tp53 | Rat | curcumin | multiple interactions | ISO | RGD:11440 | 6480464 | [Curcumin co-treated with Quercetin] inhibits the reaction [Benzo(a)pyrene results in decreased acetylation of TRP53 protein]; more ... | CTD | PMID:21519798|PMID:28681665|PMID:35817260|PMID:38301994 |
Tp53 | Rat | curcumin | increases expression | ISO | RGD:11440 | 6480464 | Curcumin results in increased expression of TRP53 mRNA | CTD | PMID:25822711 |
Tp53 | Rat | curcumin | increases expression | ISO | RGD:70502 | 6480464 | [Curcumin results in increased expression of SERPINB5] which results in increased expression of TP53 protein; more ... | CTD | PMID:19944674|PMID:23222814|PMID:25256401|PMID:25644192 |
Tp53 | Rat | curcumin | multiple interactions | EXP | | 6480464 | [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased more ... | CTD | PMID:19227835|PMID:26612707|PMID:34047412|PMID:34577062|PMID:38369055 |
Tp53 | Rat | curcumin | increases phosphorylation | ISO | RGD:70502 | 6480464 | Curcumin results in increased phosphorylation of TP53 protein | CTD | PMID:17332930|PMID:19020741|PMID:21134073 |
Tp53 | Rat | curcumin | increases acetylation | ISO | RGD:70502 | 6480464 | Curcumin results in increased acetylation of TP53 protein | CTD | PMID:17332930 |
Tp53 | Rat | curcumin | affects expression | ISO | RGD:70502 | 6480464 | Curcumin affects the expression of TP53 protein; Curcumin analog affects the expression of TP53 mRNA; more ... | CTD | PMID:17041101|PMID:24211270 |
Tp53 | Rat | curcumin | affects localization | ISO | RGD:70502 | 6480464 | Curcumin affects the localization of TP53 protein | CTD | PMID:17332930 |
Tp53 | Rat | cyanamide | multiple interactions | EXP | | 6480464 | [Ethanol co-treated with Cyanamide] results in increased expression of TP53 mRNA | CTD | PMID:12003908 |
Tp53 | Rat | cycloheximide | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 mutant form results in increased susceptibility to Cycloheximide | CTD | PMID:21875941 |
Tp53 | Rat | cycloheximide | increases degradation | ISO | RGD:70502 | 6480464 | Cycloheximide results in increased degradation of TP53 protein | CTD | PMID:31645432 |
Tp53 | Rat | cycloheximide | decreases expression | ISO | RGD:70502 | 6480464 | Cycloheximide results in decreased expression of TP53 protein | CTD | PMID:20943951|PMID:35821281 |
Tp53 | Rat | cycloheximide | multiple interactions | ISO | RGD:11440 | 6480464 | Cycloheximide inhibits the reaction [Cyclosporine results in increased expression of TRP53 protein] | CTD | PMID:10760090 |
Tp53 | Rat | cycloheximide | multiple interactions | EXP | | 6480464 | Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein] | CTD | PMID:9790906 |
Tp53 | Rat | cycloheximide | multiple interactions | ISO | RGD:70502 | 6480464 | Cycloheximide inhibits the reaction [Fluorouracil results in increased expression of TP53 protein]; Cycloheximide promotes the more ... | CTD | PMID:15016801|PMID:27993609|PMID:31645432 |
Tp53 | Rat | cyclophosphamide | multiple interactions | EXP | | 6480464 | astaxanthine inhibits the reaction [Cyclophosphamide results in increased expression of TP53 protein]; chlorophyllin inhibits the more ... | CTD | PMID:19227835|PMID:20038455|PMID:32197949 |
Tp53 | Rat | cyclophosphamide | increases activity | ISO | RGD:70502 | 6480464 | Cyclophosphamide metabolite results in increased activity of TP53 protein | CTD | PMID:20655369|PMID:22010212 |
Tp53 | Rat | cyclophosphamide | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein promotes the reaction [Methotrexate results in increased susceptibility to Cyclophosphamide metabolite] | CTD | PMID:22010212 |
Tp53 | Rat | cyclophosphamide | increases expression | EXP | | 6480464 | Cyclophosphamide results in increased expression of TP53 mRNA; Cyclophosphamide results in increased expression of TP53 more ... | CTD | PMID:20038455|PMID:32197949 |
Tp53 | Rat | cyclophosphamide | increases mutagenesis | ISO | RGD:70502 | 6480464 | Cyclophosphamide results in increased mutagenesis of TP53 exon | CTD | PMID:9610789 |
Tp53 | Rat | cyclophosphamide | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 affects the susceptibility to Cyclophosphamide | CTD | PMID:10766175 |
Tp53 | Rat | cyclophosphamide | increases mutagenesis | EXP | | 6480464 | Cyclophosphamide results in increased mutagenesis of TP53 exon | CTD | PMID:19227835 |
Tp53 | Rat | cyclophosphamide | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Cyclophosphamide | CTD | PMID:15182437 |
Tp53 | Rat | cyclosporin A | increases expression | ISO | RGD:70502 | 6480464 | Cyclosporine results in increased expression of TP53 mRNA | CTD | PMID:20106945 |
Tp53 | Rat | cyclosporin A | affects expression | EXP | | 6480464 | Cyclosporine affects the expression of TP53 protein | CTD | PMID:24971338 |
Tp53 | Rat | cyclosporin A | affects activity | EXP | | 6480464 | Cyclosporine affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | cyclosporin A | affects activity | ISO | RGD:70502 | 6480464 | Cyclosporine affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | cyclosporin A | multiple interactions | ISO | RGD:70502 | 6480464 | [Cyclosporine co-treated with NGF protein] results in increased expression of TP53 mRNA; Cyclosporine inhibits the more ... | CTD | PMID:24244623|PMID:26884717|PMID:28703385 |
Tp53 | Rat | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of TP53; Cyclosporine results in increased expression of TP53 mRNA | CTD | PMID:24971338|PMID:25299210 |
Tp53 | Rat | cyclosporin A | increases expression | ISO | RGD:11440 | 6480464 | Cyclosporine results in increased expression of TRP53 protein | CTD | PMID:10760090 |
Tp53 | Rat | cyclosporin A | multiple interactions | ISO | RGD:11440 | 6480464 | Cycloheximide inhibits the reaction [Cyclosporine results in increased expression of TRP53 protein]; Cyclosporine inhibits the more ... | CTD | PMID:10205001|PMID:10760090|PMID:26884717 |
Tp53 | Rat | cyfluthrin | increases expression | ISO | RGD:70502 | 6480464 | cyfluthrin results in increased expression of TP53 mRNA | CTD | PMID:31330490 |
Tp53 | Rat | cyhalothrin | increases expression | ISO | RGD:11440 | 6480464 | cyhalothrin results in increased expression of TRP53 mRNA | CTD | PMID:20097460 |
Tp53 | Rat | cylindrospermopsin | increases expression | EXP | | 6480464 | cylindrospermopsin results in increased expression of TP53 mRNA; cylindrospermopsin results in increased expression of TP53 more ... | CTD | PMID:34687773 |
Tp53 | Rat | cypermethrin | multiple interactions | EXP | | 6480464 | Vitamin E inhibits the reaction [cypermethrin results in increased expression of TP53 mRNA] | CTD | PMID:24759048 |
Tp53 | Rat | cypermethrin | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of TP53 mRNA] | CTD | PMID:29945211 |
Tp53 | Rat | cypermethrin | increases expression | ISO | RGD:70502 | 6480464 | cypermethrin results in increased expression of TP53 mRNA | CTD | PMID:29945211|PMID:32028016|PMID:36063984 |
Tp53 | Rat | cypermethrin | increases mutagenesis | ISO | RGD:70502 | 6480464 | cypermethrin results in increased mutagenesis of TP53 exon | CTD | PMID:28584332 |
Tp53 | Rat | cypermethrin | decreases expression | ISO | RGD:70502 | 6480464 | cypermethrin results in decreased expression of TP53 mRNA | CTD | PMID:27704156 |
Tp53 | Rat | cypermethrin | increases expression | EXP | | 6480464 | cypermethrin results in increased expression of TP53 mRNA; cypermethrin results in increased expression of TP53 more ... | CTD | PMID:22528246|PMID:24759048 |
Tp53 | Rat | cytarabine | multiple interactions | ISO | RGD:70502 | 6480464 | [fludarabine co-treated with Cytarabine co-treated with docetaxel] results in increased expression of TP53 protein; Caffeine more ... | CTD | PMID:17977830|PMID:9703875 |
Tp53 | Rat | cytarabine | affects activity | ISO | RGD:70502 | 6480464 | Cytarabine affects the activity of TP53 protein; Cytarabine metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | cytarabine | increases activity | ISO | RGD:70502 | 6480464 | Cytarabine results in increased activity of TP53 protein | CTD | PMID:22010212 |
Tp53 | Rat | cytarabine | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Cytarabine | CTD | PMID:20477944 |
Tp53 | Rat | cytarabine | increases expression | ISO | RGD:70502 | 6480464 | [Cytarabine results in increased expression of TP53 protein] which results in increased expression of BAX more ... | CTD | PMID:10200513|PMID:12082016|PMID:12781215|PMID:17977830|PMID:24675086 |
Tp53 | Rat | cytarabine | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in increased susceptibility to Cytarabine | CTD | PMID:24675086 |
Tp53 | Rat | cytarabine | increases expression | EXP | | 6480464 | Cytarabine results in increased expression of TP53 protein | CTD | PMID:14766721|PMID:15203180|PMID:22212197|PMID:9880587 |
Tp53 | Rat | cytarabine | increases phosphorylation | ISO | RGD:70502 | 6480464 | Cytarabine results in increased phosphorylation of TP53 protein | CTD | PMID:10200513|PMID:17977830|PMID:19628630 |
Tp53 | Rat | cytochalasin B | increases expression | ISO | RGD:70502 | 6480464 | Cytochalasin B results in increased expression of TP53 protein | CTD | PMID:27640744 |
Tp53 | Rat | D-fructofuranose 1,6-bisphosphate | increases expression | ISO | RGD:70502 | 6480464 | fructose-1,6-diphosphate results in increased expression of TP53 protein | CTD | PMID:33078453 |
Tp53 | Rat | D-glucose | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytic Acid inhibits the reaction [Glucose results in increased expression of more ... | CTD | PMID:20068143|PMID:21548882|PMID:24218232|PMID:24451382|PMID:26188290|PMID:27049278|PMID:33962019|PMID:35264022|PMID:38000455 |
Tp53 | Rat | D-glucose | increases expression | EXP | | 6480464 | Glucose results in increased expression of TP53 protein | CTD | PMID:38483099 |
Tp53 | Rat | D-glucose | multiple interactions | ISO | RGD:11440 | 6480464 | [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of TRP53 protein; [Oxygen deficiency more ... | CTD | PMID:28675767 |
Tp53 | Rat | D-glucose | increases expression | ISO | RGD:70502 | 6480464 | Glucose results in increased expression of TP53 mRNA; Glucose results in increased expression of TP53 more ... | CTD | PMID:26188290|PMID:27049278|PMID:35264022|PMID:38000455|PMID:38483099 |
Tp53 | Rat | D-glucose | multiple interactions | EXP | | 6480464 | [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in more ... | CTD | PMID:23451161|PMID:25997894 |
Tp53 | Rat | D-glucose | increases acetylation | ISO | RGD:70502 | 6480464 | Glucose results in increased acetylation of TP53 protein | CTD | PMID:20068143 |
Tp53 | Rat | D-glucose | affects localization | ISO | RGD:70502 | 6480464 | Glucose affects the localization of TP53 protein | CTD | PMID:24218232 |
Tp53 | Rat | D-mannitol | multiple interactions | ISO | RGD:70502 | 6480464 | Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 more ... | CTD | PMID:29803612 |
Tp53 | Rat | D-penicillamine | increases expression | ISO | RGD:70502 | 6480464 | Penicillamine results in increased expression of TP53 protein | CTD | PMID:22843330 |
Tp53 | Rat | D-penicillamine | decreases expression | ISO | RGD:70502 | 6480464 | Penicillamine results in decreased expression of TP53 mRNA | CTD | PMID:22843330 |
Tp53 | Rat | daidzein | increases expression | ISO | RGD:70502 | 6480464 | daidzein results in increased expression of TP53 protein | CTD | PMID:19800779 |
Tp53 | Rat | dapagliflozin | multiple interactions | EXP | | 6480464 | dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TP53 more ... | CTD | PMID:34391751 |
Tp53 | Rat | DAPT | decreases expression | ISO | RGD:70502 | 6480464 | N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in decreased expression of TP53 protein | CTD | PMID:25005833 |
Tp53 | Rat | DAPT | multiple interactions | ISO | RGD:70502 | 6480464 | Hydrogen Peroxide inhibits the reaction [N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in decreased expression of TP53 protein] | CTD | PMID:25005833 |
Tp53 | Rat | daunorubicin | multiple interactions | ISO | RGD:70502 | 6480464 | [Daunorubicin co-treated with Magnetite Nanoparticles] results in increased activity of TP53 protein; Daunorubicin results in more ... | CTD | PMID:21518493|PMID:23872705 |
Tp53 | Rat | daunorubicin | affects activity | ISO | RGD:70502 | 6480464 | Daunorubicin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | daunorubicin | increases phosphorylation | EXP | | 6480464 | Daunorubicin results in increased phosphorylation of TP53 protein | CTD | PMID:38290791 |
Tp53 | Rat | daunorubicin | multiple interactions | EXP | | 6480464 | Dexrazoxane inhibits the reaction [Daunorubicin results in increased phosphorylation of TP53 protein]; XK 469 inhibits more ... | CTD | PMID:38290791 |
Tp53 | Rat | daunorubicin | increases activity | ISO | RGD:70502 | 6480464 | Daunorubicin results in increased activity of TP53 protein | CTD | PMID:12112851 |
Tp53 | Rat | daunorubicin | increases expression | ISO | RGD:70502 | 6480464 | Daunorubicin results in increased expression of TP53 mRNA | CTD | PMID:12656675 |
Tp53 | Rat | DDE | increases expression | ISO | RGD:70502 | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of TP53 mRNA | CTD | PMID:19545618|PMID:38568856 |
Tp53 | Rat | DDE | increases activity | ISO | RGD:70502 | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased activity of TP53 protein | CTD | PMID:27589886 |
Tp53 | Rat | DDT | decreases expression | ISO | RGD:11440 | 6480464 | DDT results in decreased expression of TRP53 protein | CTD | PMID:23684557 |
Tp53 | Rat | DDT | decreases expression | EXP | | 6480464 | DDT results in decreased expression of TP53 mRNA; DDT results in decreased expression of TP53 more ... | CTD | PMID:25410620 |
Tp53 | Rat | DDT | increases methylation | EXP | | 6480464 | DDT results in increased methylation of TP53 promoter | CTD | PMID:25410620 |
Tp53 | Rat | DDT | multiple interactions | ISO | RGD:11440 | 6480464 | DDT inhibits the reaction [TRP53 protein binds to CDKN1A promoter] | CTD | PMID:23684557 |
Tp53 | Rat | deguelin | decreases expression | ISO | RGD:70502 | 6480464 | [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression more ... | CTD | PMID:22227970|PMID:25242579 |
Tp53 | Rat | deguelin | increases expression | ISO | RGD:70502 | 6480464 | deguelin results in increased expression of TP53 mRNA | CTD | PMID:33512557 |
Tp53 | Rat | dehydroepiandrosterone | increases expression | ISO | RGD:70502 | 6480464 | Dehydroepiandrosterone results in increased expression of TP53 mRNA | CTD | PMID:15752352 |
Tp53 | Rat | DENSPM | multiple interactions | ISO | RGD:70502 | 6480464 | N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of TP53 protein]; TP53 protein inhibits more ... | CTD | PMID:15546879 |
Tp53 | Rat | deoxycholic acid | increases expression | EXP | | 6480464 | Deoxycholic Acid results in increased expression of TP53 mRNA | CTD | PMID:20137712 |
Tp53 | Rat | deoxycholic acid | multiple interactions | EXP | | 6480464 | TP53 protein affects the reaction [[Deoxycholic Acid results in increased expression of CCND1 protein] which more ... | CTD | PMID:17431217|PMID:20137712 |
Tp53 | Rat | Deoxycorticosterone acetate | multiple interactions | EXP | | 6480464 | [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression more ... | CTD | PMID:22228705 |
Tp53 | Rat | deoxynivalenol | multiple interactions | ISO | RGD:11440 | 6480464 | [pifithrin results in decreased activity of TP53 protein] which results in decreased susceptibility to deoxynivalenol; more ... | CTD | PMID:15976193|PMID:22491426|PMID:35817260 |
Tp53 | Rat | deoxynivalenol | increases expression | ISO | RGD:11440 | 6480464 | deoxynivalenol results in increased expression of TRP53 protein | CTD | PMID:35817260 |
Tp53 | Rat | deoxynivalenol | decreases expression | ISO | RGD:70502 | 6480464 | deoxynivalenol results in decreased expression of TP53 protein | CTD | PMID:33890134 |
Tp53 | Rat | deoxynivalenol | increases expression | ISO | RGD:70502 | 6480464 | deoxynivalenol results in increased expression of TP53 mRNA | CTD | PMID:30668976 |
Tp53 | Rat | deoxynivalenol | multiple interactions | ISO | RGD:70502 | 6480464 | [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of TP53 more ... | CTD | PMID:30668976 |
Tp53 | Rat | deoxynivalenol | increases activity | ISO | RGD:70502 | 6480464 | deoxynivalenol results in increased activity of TP53 protein | CTD | PMID:19664677 |
Tp53 | Rat | Deoxyschizandrin | increases expression | ISO | RGD:70502 | 6480464 | schizandrin A results in increased expression of TP53 protein | CTD | PMID:32057180 |
Tp53 | Rat | Deoxyschizandrin | multiple interactions | ISO | RGD:70502 | 6480464 | MEG3 protein affects the reaction [schizandrin A results in increased expression of TP53 protein] | CTD | PMID:32057180 |
Tp53 | Rat | dequalinium | increases expression | ISO | RGD:70502 | 6480464 | Dequalinium results in increased expression of TP53 protein | CTD | PMID:21548882 |
Tp53 | Rat | desferrioxamine B | multiple interactions | ISO | RGD:70502 | 6480464 | [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TP53 mRNA; [Glucose co-treated with Deferoxamine] more ... | CTD | PMID:10942736|PMID:16357363|PMID:16527254|PMID:33962019|PMID:34126102|PMID:35690295 |
Tp53 | Rat | desferrioxamine B | multiple interactions | EXP | | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Deferoxamine results in increased activity of TP53 protein] which results in more ... | CTD | PMID:19950214|PMID:34577062 |
Tp53 | Rat | desferrioxamine B | decreases expression | ISO | RGD:70502 | 6480464 | Deferoxamine results in decreased expression of TP53 protein | CTD | PMID:38483099 |
Tp53 | Rat | desferrioxamine B | increases phosphorylation | EXP | | 6480464 | Deferoxamine results in increased phosphorylation of TP53 protein | CTD | PMID:17563398 |
Tp53 | Rat | desferrioxamine B | decreases expression | EXP | | 6480464 | Deferoxamine results in decreased expression of TP53 protein | CTD | PMID:38483099 |
Tp53 | Rat | desferrioxamine B | increases activity | EXP | | 6480464 | Deferoxamine results in increased activity of TP53 protein | CTD | PMID:19950214 |
Tp53 | Rat | desferrioxamine B | increases expression | ISO | RGD:70502 | 6480464 | Deferoxamine results in increased expression of TP53 protein | CTD | PMID:23483119 |
Tp53 | Rat | desferrioxamine B | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in decreased susceptibility to Deferoxamine | CTD | PMID:16527254 |
Tp53 | Rat | dexamethasone | multiple interactions | ISO | RGD:70502 | 6480464 | Dexamethasone inhibits the reaction [TP53 protein binds to FPR1 promoter] | CTD | PMID:19037090 |
Tp53 | Rat | dexamethasone | increases activity | ISO | RGD:70502 | 6480464 | Dexamethasone results in increased activity of TP53 protein | CTD | PMID:22010212 |
Tp53 | Rat | dexamethasone | multiple interactions | ISO | RGD:11440 | 6480464 | Dexamethasone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TRP53 protein] | CTD | PMID:15987750 |
Tp53 | Rat | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of TP53 mRNA | CTD | PMID:17522070 |
Tp53 | Rat | dexamethasone | decreases expression | ISO | RGD:70502 | 6480464 | Dexamethasone results in decreased expression of TP53 protein | CTD | PMID:19037090 |
Tp53 | Rat | dexmedetomidine | multiple interactions | EXP | | 6480464 | atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in more ... | CTD | PMID:30597158 |
Tp53 | Rat | dextran sulfate | increases expression | ISO | RGD:11440 | 6480464 | Dextran Sulfate results in increased expression of TRP53 protein | CTD | PMID:16049979 |
Tp53 | Rat | Di-n-octyl phthalate | multiple interactions | ISO | RGD:11440 | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated more ... | CTD | PMID:35739755 |
Tp53 | Rat | Diacetoxyscirpenol | decreases expression | ISO | RGD:11440 | 6480464 | diacetoxyscirpenol results in decreased expression of TRP53 mRNA | CTD | PMID:31836554 |
Tp53 | Rat | Dialifor | affects activity | ISO | RGD:70502 | 6480464 | dialifor metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | diallyl disulfide | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]; Glutathione inhibits more ... | CTD | PMID:11925476|PMID:19202565 |
Tp53 | Rat | diallyl disulfide | multiple interactions | EXP | | 6480464 | [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of TP53 mRNA | CTD | PMID:31077537 |
Tp53 | Rat | diallyl disulfide | increases expression | ISO | RGD:70502 | 6480464 | diallyl disulfide results in increased expression of TP53 protein | CTD | PMID:11925476|PMID:19202565 |
Tp53 | Rat | Diallyl sulfide | increases expression | EXP | | 6480464 | allyl sulfide results in increased expression of TP53 mRNA | CTD | PMID:17125941 |
Tp53 | Rat | Diallyl sulfide | increases expression | ISO | RGD:70502 | 6480464 | allyl sulfide results in increased expression of TP53 mRNA | CTD | PMID:24650757 |
Tp53 | Rat | Diallyl sulfide | multiple interactions | EXP | | 6480464 | [allyl sulfide co-treated with Diethylstilbestrol] results in increased expression of TP53 mRNA | CTD | PMID:17125941 |
Tp53 | Rat | diallyl trisulfide | increases expression | ISO | RGD:70502 | 6480464 | diallyl trisulfide results in increased expression of TP53 mRNA; diallyl trisulfide results in increased expression more ... | CTD | PMID:19823037|PMID:23754639|PMID:24415872|PMID:28571773 |
Tp53 | Rat | diallyl trisulfide | multiple interactions | ISO | RGD:70502 | 6480464 | diallyl trisulfide results in increased expression of and affects the localization of TP53 protein | CTD | PMID:19823037 |
Tp53 | Rat | diallyl trisulfide | affects localization | ISO | RGD:70502 | 6480464 | diallyl trisulfide affects the localization of TP53 protein | CTD | PMID:24415872 |
Tp53 | Rat | diarsenic trioxide | increases phosphorylation | ISO | RGD:11440 | 6480464 | Arsenic Trioxide results in increased phosphorylation of TP53 protein | CTD | PMID:27638049 |
Tp53 | Rat | diarsenic trioxide | increases expression | ISO | RGD:11440 | 6480464 | Arsenic Trioxide results in increased expression of TRP53 mRNA; Arsenic Trioxide results in increased expression more ... | CTD | PMID:34091186 |
Tp53 | Rat | diarsenic trioxide | increases degradation | ISO | RGD:70502 | 6480464 | Arsenic Trioxide results in increased degradation of TP53 protein | CTD | PMID:19457607 |
Tp53 | Rat | diarsenic trioxide | decreases expression | ISO | RGD:70502 | 6480464 | Arsenic Trioxide results in decreased expression of TP53 mRNA; Arsenic Trioxide results in decreased expression more ... | CTD | PMID:21454520|PMID:27825931|PMID:29164574|PMID:36442592 |
Tp53 | Rat | diarsenic trioxide | increases expression | ISO | RGD:70502 | 6480464 | Arsenic Trioxide results in increased expression of TP53 mRNA; Arsenic Trioxide results in increased expression more ... | CTD | PMID:10841286|PMID:10850458|PMID:11146441|PMID:11834893|PMID:12490120|PMID:15352174|PMID:15904916|PMID:15979894|PMID:16467208|PMID:17530438|PMID:19444595|PMID:19769630|PMID:20200477|PMID:20953137|PMID:21454520|PMID:21792014|PMID:23440206|PMID:23851143|PMID:26110921|PMID:27430728|PMID:29274334|PMID:31307525|PMID:31734849|PMID:32017938|PMID:34042274 |
Tp53 | Rat | diarsenic trioxide | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 affects the susceptibility to Arsenic Trioxide; TP53 protein affects the susceptibility to Arsenic Trioxide | CTD | PMID:12851490|PMID:29535630|PMID:35030298 |
Tp53 | Rat | diarsenic trioxide | increases activity | EXP | | 6480464 | Arsenic Trioxide results in increased activity of TP53 protein | CTD | PMID:17487067 |
Tp53 | Rat | diarsenic trioxide | multiple interactions | ISO | RGD:11440 | 6480464 | Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in increased more ... | CTD | PMID:21565247|PMID:27638049|PMID:34091186 |
Tp53 | Rat | diarsenic trioxide | increases phosphorylation | ISO | RGD:70502 | 6480464 | Arsenic Trioxide results in increased phosphorylation of TP53 protein | CTD | PMID:29944906|PMID:30472098|PMID:36801614 |
Tp53 | Rat | diarsenic trioxide | multiple interactions | ISO | RGD:70502 | 6480464 | [Arsenic Trioxide co-treated with Curcumin] results in increased expression of TP53 protein; [Arsenic Trioxide co-treated more ... | CTD | PMID:12851490|PMID:15904916|PMID:17064470|PMID:18167198|PMID:20377131|PMID:23851143|PMID:23968587|PMID:24738333|PMID:25574600|PMID:26110921|PMID:27430728|PMID:29266867|PMID:29274334|PMID:29944906|PMID:30012499|PMID:31307525|PMID:31734849|PMID:32017938|PMID:34042274|PMID:36352148 |
Tp53 | Rat | diarsenic trioxide | affects expression | ISO | RGD:70502 | 6480464 | Arsenic Trioxide affects the expression of TP53 | CTD | PMID:11775218 |
Tp53 | Rat | diarsenic trioxide | increases phosphorylation | EXP | | 6480464 | Arsenic Trioxide results in increased phosphorylation of TP53 protein | CTD | PMID:23337567 |
Tp53 | Rat | diarsenic trioxide | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein mutant form results in decreased susceptibility to Arsenic Trioxide | CTD | PMID:21454520|PMID:24884809 |
Tp53 | Rat | diarsenic trioxide | multiple interactions | EXP | | 6480464 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of TP53 protein]; pifithrin inhibits more ... | CTD | PMID:17487067|PMID:23337567|PMID:29130132 |
Tp53 | Rat | diarsenic trioxide | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of TP53 mRNA; Arsenic Trioxide results in increased expression more ... | CTD | PMID:21145380|PMID:22801079|PMID:29130132|PMID:31734849 |
Tp53 | Rat | diazinon | increases expression | EXP | | 6480464 | Diazinon results in increased expression of TP53 mRNA | CTD | PMID:17452286 |
Tp53 | Rat | diazinon | increases expression | ISO | RGD:70502 | 6480464 | Diazinon results in increased expression of TP53 mRNA | CTD | PMID:27920530 |
Tp53 | Rat | diazinon | multiple interactions | ISO | RGD:70502 | 6480464 | [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression more ... | CTD | PMID:27920530 |
Tp53 | Rat | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of TP53 mRNA | CTD | PMID:22546817 |
Tp53 | Rat | diazoxide | decreases expression | EXP | | 6480464 | Diazoxide results in decreased expression of TP53 mRNA | CTD | PMID:16426753 |
Tp53 | Rat | diazoxon | affects activity | ISO | RGD:70502 | 6480464 | diazoxon metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | dibenz[a,h]anthracene | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the reaction [1,2,5,6-dibenzanthracene results in increased expression of CYP1A1 protein] | CTD | PMID:25398514 |
Tp53 | Rat | dibenz[a,h]anthracene | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to 1,2,5,6-dibenzanthracene | CTD | PMID:25398514 |
Tp53 | Rat | Dibenzo[a,e]pyrene | increases phosphorylation | EXP | | 6480464 | dibenzo(a,e)pyrene results in increased phosphorylation of TP53 protein | CTD | PMID:17961608 |
Tp53 | Rat | dibenzo[a,l]pyrene | multiple interactions | ISO | RGD:70502 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [dibenzo(a,l)pyrene affects the localization of and results in increased expression of more ... | CTD | PMID:24954032|PMID:25398514 |
Tp53 | Rat | dibenzo[a,l]pyrene | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to dibenzo(a,l)pyrene | CTD | PMID:25398514 |
Tp53 | Rat | dibenzo[a,l]pyrene | increases phosphorylation | EXP | | 6480464 | dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein | CTD | PMID:16005925|PMID:17961608 |
Tp53 | Rat | dibenzo[a,l]pyrene | increases expression | ISO | RGD:70502 | 6480464 | dibenzo(a,l)pyrene results in increased expression of TP53 protein | CTD | PMID:15548639 |
Tp53 | Rat | dibenzo[a,l]pyrene | increases expression | ISO | RGD:11440 | 6480464 | dibenzo(a,l)pyrene results in increased expression of TRP53 protein | CTD | PMID:20353797 |
Tp53 | Rat | dibenzo[a,l]pyrene | multiple interactions | ISO | RGD:11440 | 6480464 | [dibenzo(a,l)pyrene co-treated with sodium arsenite] results in increased expression of TRP53 protein | CTD | PMID:20353797 |
Tp53 | Rat | dibenzo[a,l]pyrene | multiple interactions | EXP | | 6480464 | pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein]; SB 203580 inhibits more ... | CTD | PMID:16005925 |
Tp53 | Rat | Dibutyl phosphate | affects binding | ISO | RGD:70502 | 6480464 | di-n-butylphosphoric acid binds to TP53 gene | CTD | PMID:25510514 |
Tp53 | Rat | Dibutyl phosphate | affects expression | ISO | RGD:70502 | 6480464 | di-n-butylphosphoric acid affects the expression of TP53 mRNA | CTD | PMID:37042841 |
Tp53 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of TP53 protein | CTD | PMID:28067064 |
Tp53 | Rat | dibutyl phthalate | multiple interactions | ISO | RGD:11440 | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated more ... | CTD | PMID:35739755 |
Tp53 | Rat | dibutyl phthalate | increases methylation | ISO | RGD:70502 | 6480464 | Dibutyl Phthalate results in increased methylation of TP53 promoter | CTD | PMID:35487445 |
Tp53 | Rat | dibutyl phthalate | decreases expression | ISO | RGD:70502 | 6480464 | Dibutyl Phthalate results in decreased expression of TP53 mRNA | CTD | PMID:35487445 |
Tp53 | Rat | dichlorine | increases expression | ISO | RGD:70502 | 6480464 | Chlorine results in increased expression of TP53 protein modified form | CTD | PMID:35065218 |
Tp53 | Rat | dichlorine | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine promotes the reaction [Chlorine results in increased expression of TP53 protein modified form] | CTD | PMID:35065218 |
Tp53 | Rat | dichloroacetic acid | increases expression | ISO | RGD:11440 | 6480464 | Dichloroacetic Acid results in increased expression of TRP53 protein | CTD | PMID:22705712 |
Tp53 | Rat | Dichlorophen | affects activity | ISO | RGD:70502 | 6480464 | Dichlorophen affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | dichlorvos | decreases expression | EXP | | 6480464 | Dichlorvos results in decreased expression of TP53 mRNA | CTD | PMID:23053939 |
Tp53 | Rat | dichlorvos | increases expression | EXP | | 6480464 | Dichlorvos results in increased expression of TP53 mRNA; Dichlorvos results in increased expression of TP53 more ... | CTD | PMID:24369695 |
Tp53 | Rat | dichlorvos | multiple interactions | EXP | | 6480464 | TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 mRNA]; TEMPOL-H inhibits the more ... | CTD | PMID:24369695 |
Tp53 | Rat | dichromic acid | increases expression | ISO | RGD:70502 | 6480464 | chromic acid results in increased expression of TP53 mRNA | CTD | PMID:27005777 |
Tp53 | Rat | diclofenac | multiple interactions | ISO | RGD:11440 | 6480464 | Diclofenac promotes the reaction [Doxorubicin results in increased expression of TRP53 protein] | CTD | PMID:15458769 |
Tp53 | Rat | diclofenac | increases expression | EXP | | 6480464 | Diclofenac results in increased expression of TP53 mRNA | CTD | PMID:29027214 |
Tp53 | Rat | diclofenac | increases expression | ISO | RGD:70502 | 6480464 | Diclofenac results in increased expression of TP53 mRNA; Diclofenac results in increased expression of TP53 more ... | CTD | PMID:29027214|PMID:32087850 |
Tp53 | Rat | diclofenac | affects expression | ISO | RGD:70502 | 6480464 | Diclofenac affects the expression of TP53 mRNA | CTD | PMID:24752500 |
Tp53 | Rat | dicoumarol | multiple interactions | ISO | RGD:70502 | 6480464 | Dicumarol inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein modified form]; more ... | CTD | PMID:14634213|PMID:16061648|PMID:17959154|PMID:26630137 |
Tp53 | Rat | dicoumarol | decreases expression | ISO | RGD:70502 | 6480464 | Dicumarol results in decreased expression of TP53 protein | CTD | PMID:22692362 |
Tp53 | Rat | dicoumarol | increases degradation | ISO | RGD:70502 | 6480464 | Dicumarol results in increased degradation of TP53 protein | CTD | PMID:14634213 |
Tp53 | Rat | dicrotophos | increases expression | ISO | RGD:70502 | 6480464 | dicrotophos results in increased expression of TP53 mRNA | CTD | PMID:28302478 |
Tp53 | Rat | dicrotophos | affects activity | ISO | RGD:70502 | 6480464 | dicrotophos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Dictamnine | increases expression | ISO | RGD:70502 | 6480464 | dictamnine results in increased expression of TP53 protein | CTD | PMID:34861243 |
Tp53 | Rat | dicyclanil | increases expression | ISO | RGD:11440 | 6480464 | dicyclanil results in increased expression of TRP53 mRNA | CTD | PMID:15664270 |
Tp53 | Rat | Didecyldimethylammonium | increases expression | ISO | RGD:70502 | 6480464 | didecyldimethylammonium results in increased expression of TP53 protein modified form | CTD | PMID:32763356 |
Tp53 | Rat | dieckol | multiple interactions | ISO | RGD:11440 | 6480464 | dieckol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TRP53 mRNA] | CTD | PMID:33347706 |
Tp53 | Rat | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of TP53 mRNA | CTD | PMID:22546817 |
Tp53 | Rat | dieldrin | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in decreased susceptibility to Dieldrin | CTD | PMID:32421776 |
Tp53 | Rat | dieldrin | increases activity | ISO | RGD:11440 | 6480464 | Dieldrin results in increased activity of TRP53 protein | CTD | PMID:22634143 |
Tp53 | Rat | dienestrol | affects activity | ISO | RGD:70502 | 6480464 | Dienestrol affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | diepoxybutane | increases expression | ISO | RGD:70502 | 6480464 | diepoxybutane results in increased expression of TP53 protein | CTD | PMID:14998682 |
Tp53 | Rat | diepoxybutane | increases phosphorylation | ISO | RGD:70502 | 6480464 | diepoxybutane results in increased phosphorylation of TP53 protein | CTD | PMID:29405768 |
Tp53 | Rat | diepoxybutane | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diepoxybutane results in increased phosphorylation of TP53 protein]; ATM protein affects more ... | CTD | PMID:20024960|PMID:29405768|PMID:31953984|PMID:36775894 |
Tp53 | Rat | diethanolamine | decreases expression | ISO | RGD:11440 | 6480464 | diethanolamine results in decreased expression of TRP53 mRNA | CTD | PMID:16014740 |
Tp53 | Rat | diethanolamine | decreases expression | EXP | | 6480464 | diethanolamine results in decreased expression of TP53 mRNA | CTD | PMID:16014740 |
Tp53 | Rat | diethyl maleate | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 protein affects the reaction [diethyl maleate results in increased expression of BTG2 mRNA] | CTD | PMID:22003191 |
Tp53 | Rat | diethyl maleate | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]; TP53 more ... | CTD | PMID:27982581 |
Tp53 | Rat | diethyl phthalate | multiple interactions | ISO | RGD:11440 | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated more ... | CTD | PMID:35739755 |
Tp53 | Rat | diethyl sulfate | increases expression | ISO | RGD:70502 | 6480464 | diethyl sulfate results in increased expression of TP53 protein | CTD | PMID:23830811 |
Tp53 | Rat | diethyl sulfate | decreases expression | ISO | RGD:70502 | 6480464 | diethyl sulfate results in decreased expression of TP53 protein | CTD | PMID:23830811 |
Tp53 | Rat | diethyldithiocarbamic acid | multiple interactions | ISO | RGD:70502 | 6480464 | Ditiocarb inhibits the reaction [cobaltous chloride results in increased expression of and results in increased more ... | CTD | PMID:10951577 |
Tp53 | Rat | diethyldithiocarbamic acid | increases expression | ISO | RGD:70502 | 6480464 | Ditiocarb results in increased expression of TP53 protein | CTD | PMID:11964141 |
Tp53 | Rat | diethylstilbestrol | multiple interactions | EXP | | 6480464 | [allyl sulfide co-treated with Diethylstilbestrol] results in increased expression of TP53 mRNA | CTD | PMID:17125941 |
Tp53 | Rat | diethylstilbestrol | decreases expression | ISO | RGD:70502 | 6480464 | Diethylstilbestrol results in decreased expression of TP53 mRNA | CTD | PMID:27825931 |
Tp53 | Rat | diethylstilbestrol | increases expression | ISO | RGD:11440 | 6480464 | Diethylstilbestrol results in increased expression of TRP53 mRNA; Diethylstilbestrol results in increased expression of TRP53 more ... | CTD | PMID:15545218|PMID:16510352|PMID:9667752 |
Tp53 | Rat | diethylstilbestrol | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 affects the susceptibility to Diethylstilbestrol | CTD | PMID:15545218 |
Tp53 | Rat | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of TP53 mRNA | CTD | PMID:17011747 |
Tp53 | Rat | diethylstilbestrol | decreases expression | EXP | | 6480464 | Diethylstilbestrol results in decreased expression of TP53 mRNA | CTD | PMID:17125941 |
Tp53 | Rat | digitoxin | decreases expression | ISO | RGD:70502 | 6480464 | Digitoxin analog results in decreased expression of TP53 protein; Digitoxin results in decreased expression of more ... | CTD | PMID:22037315 |
Tp53 | Rat | dihydroartemisinin | increases phosphorylation | ISO | RGD:70502 | 6480464 | artenimol results in increased phosphorylation of TP53 protein | CTD | PMID:21547369 |
Tp53 | Rat | dihydroartemisinin | multiple interactions | ISO | RGD:70502 | 6480464 | artenimol inhibits the reaction [TP53 protein mutant form results in increased export of Doxorubicin]; artenimol more ... | CTD | PMID:31976328 |
Tp53 | Rat | dihydrocapsaicin | increases phosphorylation | ISO | RGD:70502 | 6480464 | dihydrocapsaicin results in increased phosphorylation of TP53 protein | CTD | PMID:19139269 |
Tp53 | Rat | dihydrolipoic acid | multiple interactions | ISO | RGD:11440 | 6480464 | 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide inhibits the reaction [dihydrolipoic acid results in increased expression of TRP53 mRNA]; Acetylcysteine inhibits more ... | CTD | PMID:21462292 |
Tp53 | Rat | dihydrolipoic acid | increases expression | ISO | RGD:11440 | 6480464 | dihydrolipoic acid results in increased expression of TRP53 mRNA | CTD | PMID:21462292 |
Tp53 | Rat | Diisodecyl phthalate | multiple interactions | ISO | RGD:11440 | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated more ... | CTD | PMID:35739755 |
Tp53 | Rat | diisononyl phthalate | multiple interactions | ISO | RGD:11440 | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated more ... | CTD | PMID:35739755 |
Tp53 | Rat | Dimefox | increases expression | ISO | RGD:70502 | 6480464 | dimefox results in increased expression of TP53 mRNA | CTD | PMID:18418871 |
Tp53 | Rat | dimethylarsinic acid | increases expression | EXP | | 6480464 | Cacodylic Acid results in increased expression of TP53 mRNA | CTD | PMID:17720352 |
Tp53 | Rat | dimethylarsinic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TP53 more ... | CTD | PMID:23192986 |
Tp53 | Rat | dimetilan | affects activity | ISO | RGD:70502 | 6480464 | dimetilan metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | dinophysistoxin 2 | affects localization | ISO | RGD:70502 | 6480464 | dinophysistoxin 2 affects the localization of TP53 protein | CTD | PMID:21512803 |
Tp53 | Rat | dioscin | multiple interactions | ISO | RGD:11440 | 6480464 | dioscin inhibits the reaction [Acetaminophen results in increased expression of TRP53 protein]; dioscin inhibits the more ... | CTD | PMID:22939915|PMID:24146112 |
Tp53 | Rat | dioscin | increases expression | ISO | RGD:70502 | 6480464 | dioscin results in increased expression of TP53 mRNA; dioscin results in increased expression of TP53 more ... | CTD | PMID:22334414|PMID:29990575 |
Tp53 | Rat | dioscin | multiple interactions | EXP | | 6480464 | dioscin inhibits the reaction [Ethanol results in increased expression of TRP53 protein] | CTD | PMID:24146112 |
Tp53 | Rat | diosmin | multiple interactions | EXP | | 6480464 | Diosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein] | CTD | PMID:23665045 |
Tp53 | Rat | dioxygen | multiple interactions | ISO | RGD:70502 | 6480464 | 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]; [Betulinic more ... | CTD | PMID:10951577|PMID:19578757|PMID:23144690|PMID:29690507|PMID:30381462|PMID:32992648|PMID:33181113|PMID:34126102|PMID:35123992 |
Tp53 | Rat | dioxygen | increases metabolic processing | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in increased metabolism of Oxygen | CTD | PMID:33070465 |
Tp53 | Rat | dioxygen | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein mutant form results in increased susceptibility to Oxygen deficiency | CTD | PMID:30381462 |
Tp53 | Rat | dioxygen | increases stability | ISO | RGD:70502 | 6480464 | Oxygen deficiency results in increased stability of TP53 protein | CTD | PMID:30381462 |
Tp53 | Rat | dioxygen | increases expression | ISO | RGD:70502 | 6480464 | Oxygen deficiency results in increased expression of TP53 protein; Oxygen deficiency results in increased expression more ... | CTD | PMID:29690507|PMID:35123992 |
Tp53 | Rat | dioxygen | multiple interactions | ISO | RGD:11440 | 6480464 | [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of TRP53 protein; [Oxygen deficiency more ... | CTD | PMID:28675767 |
Tp53 | Rat | dioxygen | affects activity | ISO | RGD:70502 | 6480464 | Oxygen deficiency affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | dioxygen | increases expression | EXP | | 6480464 | Oxygen deficiency results in increased expression of TP53 protein | CTD | PMID:10657591 |
Tp53 | Rat | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of TP53 protein; mangiferin inhibits more ... | CTD | PMID:10657591|PMID:23451161 |
Tp53 | Rat | dioxygen | increases expression | ISO | RGD:11440 | 6480464 | Oxygen deficiency results in increased expression of TRP53 protein | CTD | PMID:10951577 |
Tp53 | Rat | diphenoxylate | affects activity | ISO | RGD:70502 | 6480464 | Diphenoxylate affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | dipyridamole | affects activity | ISO | RGD:70502 | 6480464 | Dipyridamole metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | diquat | multiple interactions | EXP | | 6480464 | Diquat results in increased expression of and affects the localization of TP53 protein; pifithrin inhibits more ... | CTD | PMID:29484840 |
Tp53 | Rat | disodium selenite | increases phosphorylation | ISO | RGD:70502 | 6480464 | Sodium Selenite results in increased phosphorylation of TP53 protein | CTD | PMID:15845651 |
Tp53 | Rat | disodium selenite | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Sodium Selenite | CTD | PMID:22200533 |
Tp53 | Rat | disodium selenite | multiple interactions | ISO | RGD:11440 | 6480464 | Diethylhexyl Phthalate inhibits the reaction [Sodium Selenite results in decreased expression of TRP53 protein]; Sodium more ... | CTD | PMID:20659492 |
Tp53 | Rat | disodium selenite | decreases expression | ISO | RGD:11440 | 6480464 | Sodium Selenite results in decreased expression of TRP53 protein | CTD | PMID:20659492 |
Tp53 | Rat | disodium selenite | increases expression | ISO | RGD:11440 | 6480464 | Sodium Selenite results in increased expression of TRP53 mRNA | CTD | PMID:16542727 |
Tp53 | Rat | disodium selenite | multiple interactions | ISO | RGD:70502 | 6480464 | Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of TP53 protein]; Sodium Selenite more ... | CTD | PMID:20390378|PMID:21515331 |
Tp53 | Rat | disulfoton | affects activity | ISO | RGD:70502 | 6480464 | Disulfoton metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | donepezil hydrochloride | multiple interactions | EXP | | 6480464 | Donepezil inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] | CTD | PMID:19345205 |
Tp53 | Rat | dopamine | multiple interactions | ISO | RGD:70502 | 6480464 | [Dopamine results in increased expression of HIF1A protein] which results in increased expression of and more ... | CTD | PMID:19410601 |
Tp53 | Rat | dopamine | increases expression | ISO | RGD:70502 | 6480464 | [Dopamine results in increased expression of HIF1A protein] which results in increased expression of TP53 more ... | CTD | PMID:19410601 |
Tp53 | Rat | dorsomorphin | affects localization | ISO | RGD:70502 | 6480464 | dorsomorphin affects the localization of TP53 protein | CTD | PMID:23274516 |
Tp53 | Rat | dorsomorphin | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to dorsomorphin | CTD | PMID:23274516 |
Tp53 | Rat | dorsomorphin | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [dorsomorphin results in increased expression of and results in increased phosphorylation more ... | CTD | PMID:19020741|PMID:23274516 |
Tp53 | Rat | doxorubicin | increases phosphorylation | ISO | RGD:70502 | 6480464 | Doxorubicin results in increased phosphorylation of TP53 protein | CTD | PMID:15177039|PMID:15671536|PMID:19106633|PMID:20346999 |
Tp53 | Rat | doxorubicin | affects activity | ISO | RGD:70502 | 6480464 | Doxorubicin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | doxorubicin | increases acetylation | EXP | | 6480464 | Doxorubicin results in increased acetylation of TP53 protein | CTD | PMID:34713381 |
Tp53 | Rat | doxorubicin | increases acetylation | ISO | RGD:11440 | 6480464 | Doxorubicin results in increased acetylation of TRP53 protein | CTD | PMID:34713381 |
Tp53 | Rat | doxorubicin | increases export | ISO | RGD:70502 | 6480464 | TP53 protein mutant form results in increased export of Doxorubicin | CTD | PMID:31976328 |
Tp53 | Rat | doxorubicin | decreases expression | ISO | RGD:11440 | 6480464 | Doxorubicin results in decreased expression of TRP53 mRNA | CTD | PMID:29653124|PMID:38244039 |
Tp53 | Rat | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of TP53 mRNA | CTD | PMID:27255381 |
Tp53 | Rat | doxorubicin | increases activity | ISO | RGD:70502 | 6480464 | Doxorubicin results in increased activity of TP53 protein | CTD | PMID:15141020|PMID:17124180|PMID:22010212 |
Tp53 | Rat | doxorubicin | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein mutant form affects the susceptibility to Doxorubicin | CTD | PMID:24812279 |
Tp53 | Rat | doxorubicin | increases phosphorylation | EXP | | 6480464 | Doxorubicin results in increased phosphorylation of TP53 protein | CTD | PMID:32652078|PMID:38651543 |
Tp53 | Rat | doxorubicin | increases expression | ISO | RGD:11440 | 6480464 | Doxorubicin results in increased expression of TP53 protein; Doxorubicin results in increased expression of TRP53 more ... | CTD | PMID:15458769|PMID:16949053|PMID:20144634|PMID:20363884|PMID:22763982|PMID:25665036|PMID:25896364|PMID:29653124|PMID:34713381|PMID:36811345|PMID:38395252 |
Tp53 | Rat | doxorubicin | increases activity | ISO | RGD:11440 | 6480464 | Doxorubicin results in increased activity of TRP53 protein | CTD | PMID:12006519|PMID:16949053|PMID:24586632 |
Tp53 | Rat | doxorubicin | affects localization | ISO | RGD:11440 | 6480464 | Doxorubicin affects the localization of TRP53 protein | CTD | PMID:20955365 |
Tp53 | Rat | doxorubicin | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Doxorubicin | CTD | PMID:14704126|PMID:15601469|PMID:15823547|PMID:16211088|PMID:20856197|PMID:9395239 |
Tp53 | Rat | doxorubicin | increases stability | ISO | RGD:70502 | 6480464 | Doxorubicin results in increased stability of TP53 protein | CTD | PMID:25124555 |
Tp53 | Rat | doxorubicin | affects expression | ISO | RGD:70502 | 6480464 | Doxorubicin affects the expression of TP53 mRNA; Doxorubicin affects the expression of TP53 protein | CTD | PMID:12006519|PMID:17893511|PMID:27825931|PMID:35218280 |
Tp53 | Rat | doxorubicin | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein results in increased susceptibility to Doxorubicin | CTD | PMID:10969820 |
Tp53 | Rat | doxorubicin | decreases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in decreased susceptibility to Doxorubicin; TRP53 gene polymorphism results in more ... | CTD | PMID:16013437|PMID:16843502|PMID:17404018|PMID:19103993 |
Tp53 | Rat | doxorubicin | multiple interactions | ISO | RGD:11440 | 6480464 | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Doxorubicin results in increased expression of TRP53 more ... | CTD | PMID:10969820|PMID:14766674|PMID:15458769|PMID:16013437|PMID:16432175|PMID:16843502|PMID:17404018|PMID:20363884|PMID:22242153|PMID:22763982|PMID:24586632|PMID:24812279|PMID:25665036|PMID:25896364|PMID:36811345|PMID:38395252 |
Tp53 | Rat | doxorubicin | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in decreased susceptibility to Doxorubicin; TP53 protein mutant form results more ... | CTD | PMID:15578696|PMID:17369602|PMID:31976328 |
Tp53 | Rat | doxorubicin | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 gene affects the susceptibility to Doxorubicin; TP53 protein affects the susceptibility to Doxorubicin | CTD | PMID:15182437|PMID:17085670|PMID:17912235|PMID:25124555|PMID:36634904|PMID:39427782 |
Tp53 | Rat | doxorubicin | increases glutathionylation | ISO | RGD:70502 | 6480464 | Doxorubicin results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | doxorubicin | increases expression | ISO | RGD:70502 | 6480464 | Doxorubicin results in increased expression of TP53; Doxorubicin results in increased expression of TP53 mRNA; more ... | CTD | PMID:10969820|PMID:11779855|PMID:12082016|PMID:14665630|PMID:15555623|PMID:15601469|PMID:15671536|PMID:15763944|PMID:15781256|PMID:15939500|PMID:16001973|PMID:16013437|PMID:16108013|PMID:16404146|PMID:16537896|PMID:16857806|PMID:17088865|PMID:17285121|PMID:17339365|PMID:17912235|PMID:17959036|PMID:18377724|PMID:19074854|PMID:19351845|PMID:19560264|PMID:20856197|PMID:20978201|PMID:21356574|PMID:21624110|PMID:22927544|PMID:26025680|PMID:26969377|PMID:27129209|PMID:34126102|PMID:34783124|PMID:36442531|PMID:36634904|PMID:38423379 |
Tp53 | Rat | doxorubicin | increases acetylation | ISO | RGD:70502 | 6480464 | Doxorubicin results in increased acetylation of TP53 protein; Doxorubicin results in increased acetylation of TP53 more ... | CTD | PMID:16826403|PMID:27129209 |
Tp53 | Rat | doxorubicin | decreases expression | ISO | RGD:70502 | 6480464 | Doxorubicin results in decreased expression of TP53 mRNA | CTD | PMID:18510171 |
Tp53 | Rat | doxorubicin | affects localization | ISO | RGD:70502 | 6480464 | Doxorubicin affects the localization of TP53 protein | CTD | PMID:19363521|PMID:26025680 |
Tp53 | Rat | doxorubicin | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of more ... | CTD | PMID:11779855|PMID:15059885|PMID:15489221|PMID:15578696|PMID:15763944|PMID:15823547|PMID:15939500|PMID:16168113|PMID:16432175|PMID:16826403|PMID:17079232|PMID:17088865|PMID:17124180|PMID:17285121|PMID:17608641|PMID:17634554|PMID:17653088|PMID:17682292|PMID:17912235|PMID:17959036|PMID:18269916|PMID:18377724|PMID:18698031|PMID:19074854|PMID:19106633|PMID:19351845|PMID:19363521|PMID:19714248|PMID:20155316|PMID:20856197|PMID:21624110|PMID:22927544|PMID:24738333|PMID:24816189|PMID:25124555|PMID:26025680|PMID:26969377|PMID:27129209|PMID:27163855|PMID:27634759|PMID:30258081|PMID:31976328|PMID:34126102|PMID:34783124|PMID:35218280|PMID:36634904|PMID:37345903|PMID:37406984|PMID:39427782|PMID:9815696 |
Tp53 | Rat | doxorubicin | multiple interactions | EXP | | 6480464 | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt promotes the reaction [Doxorubicin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased more ... | CTD | PMID:16687611|PMID:17285121|PMID:18632596|PMID:18775851|PMID:22015447|PMID:22155320|PMID:24902966|PMID:25997894|PMID:26318906|PMID:30836069|PMID:30885636|PMID:32652078|PMID:34047412|PMID:34273911|PMID:34713381|PMID:38395252|PMID:38651543|PMID:39214269 |
Tp53 | Rat | doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of TP53 mRNA; Doxorubicin results in increased expression of TP53 more ... | CTD | PMID:15667795|PMID:15983034|PMID:17285121|PMID:18632596|PMID:18775851|PMID:20470772|PMID:21194538|PMID:22015447|PMID:22155320|PMID:24902966|PMID:25997894|PMID:26318906|PMID:30009776|PMID:30836069|PMID:30885636|PMID:34047412|PMID:34273911|PMID:34713381|PMID:38395252 |
Tp53 | Rat | edifenphos | affects activity | ISO | RGD:70502 | 6480464 | edifenphos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | eflornithine | increases expression | EXP | | 6480464 | Eflornithine results in increased expression of TP53 mRNA | CTD | PMID:11502571 |
Tp53 | Rat | eflornithine | increases stability | EXP | | 6480464 | Eflornithine results in increased stability of TP53 mRNA; Eflornithine results in increased stability of TP53 more ... | CTD | PMID:11502571 |
Tp53 | Rat | eflornithine | multiple interactions | EXP | | 6480464 | Spermidine inhibits the reaction [Eflornithine results in increased expression of TP53 mRNA] | CTD | PMID:11502571 |
Tp53 | Rat | EHT 1864 | affects expression | ISO | RGD:70502 | 6480464 | EHT 1864 affects the expression of TP53 protein | CTD | PMID:35331739 |
Tp53 | Rat | elemental selenium | multiple interactions | ISO | RGD:70502 | 6480464 | [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression more ... | CTD | PMID:19244175|PMID:27920530 |
Tp53 | Rat | elemental selenium | decreases expression | ISO | RGD:70502 | 6480464 | Selenium results in decreased expression of TP53 protein | CTD | PMID:17523932 |
Tp53 | Rat | elemental selenium | multiple interactions | EXP | | 6480464 | [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 more ... | CTD | PMID:16600092|PMID:21628957|PMID:37987225 |
Tp53 | Rat | elemental selenium | increases expression | ISO | RGD:70502 | 6480464 | Selenium results in increased expression of TP53 mRNA | CTD | PMID:19244175 |
Tp53 | Rat | ellagic acid | increases expression | ISO | RGD:70502 | 6480464 | Ellagic Acid results in increased expression of TP53 mRNA; Ellagic Acid results in increased expression more ... | CTD | PMID:23554011|PMID:35179410 |
Tp53 | Rat | ellagic acid | multiple interactions | ISO | RGD:70502 | 6480464 | Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]; pifithrin inhibits more ... | CTD | PMID:15735102 |
Tp53 | Rat | ellagic acid | multiple interactions | EXP | | 6480464 | Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 mRNA]; Ellagic Acid more ... | CTD | PMID:27965107 |
Tp53 | Rat | ellipticine | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein promotes the reaction [[ellipticine results in increased susceptibility to Benzo(a)pyrene] which results in more ... | CTD | PMID:29471073 |
Tp53 | Rat | ellipticine | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to ellipticine | CTD | PMID:29471073 |
Tp53 | Rat | ellipticine | increases expression | ISO | RGD:70502 | 6480464 | ellipticine results in increased expression of TP53 protein | CTD | PMID:29471073 |
Tp53 | Rat | emodin | affects expression | EXP | | 6480464 | Emodin affects the expression of TP53 protein | CTD | PMID:19549930 |
Tp53 | Rat | emodin | increases expression | EXP | | 6480464 | Emodin results in increased expression of TP53 protein | CTD | PMID:37393915 |
Tp53 | Rat | emodin | multiple interactions | EXP | | 6480464 | 2-tert-butylhydroquinone inhibits the reaction [Emodin results in increased expression of TP53 protein]; AKT activator SC79 more ... | CTD | PMID:37393915 |
Tp53 | Rat | emodin | increases expression | ISO | RGD:11440 | 6480464 | Emodin results in increased expression of TP53 protein | CTD | PMID:37393915 |
Tp53 | Rat | emtricitabine | multiple interactions | ISO | RGD:70502 | 6480464 | [Emtricitabine co-treated with Tenofovir] results in increased expression of TP53 protein | CTD | PMID:31545371 |
Tp53 | Rat | endosulfan | increases expression | ISO | RGD:70502 | 6480464 | Endosulfan results in increased expression of TP53 mRNA | CTD | PMID:29705383 |
Tp53 | Rat | endrin | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Endrin | CTD | PMID:10802220 |
Tp53 | Rat | entinostat | multiple interactions | ISO | RGD:70502 | 6480464 | entinostat promotes the reaction [Etoposide results in increased expression of and results in increased acetylation more ... | CTD | PMID:25699604 |
Tp53 | Rat | entinostat | increases expression | ISO | RGD:70502 | 6480464 | entinostat results in increased expression of TP53 protein | CTD | PMID:25699604 |
Tp53 | Rat | enzyme inhibitor | multiple interactions | ISO | RGD:70502 | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 |
Tp53 | Rat | EPN | affects activity | ISO | RGD:70502 | 6480464 | Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | epoxiconazole | decreases expression | ISO | RGD:11440 | 6480464 | epoxiconazole results in decreased expression of TRP53 mRNA | CTD | PMID:35436446 |
Tp53 | Rat | erdosteine | multiple interactions | ISO | RGD:11440 | 6480464 | erdosteine inhibits the reaction [Cisplatin affects the localization of TRP53 protein modified form]; erdosteine inhibits more ... | CTD | PMID:26193055 |
Tp53 | Rat | erlotinib hydrochloride | multiple interactions | ISO | RGD:70502 | 6480464 | Erlotinib Hydrochloride promotes the reaction [Arsenic Trioxide results in increased expression of TP53 mRNA]; Erlotinib more ... | CTD | PMID:25895606|PMID:29274334 |
Tp53 | Rat | erlotinib hydrochloride | increases expression | ISO | RGD:70502 | 6480464 | Erlotinib Hydrochloride results in increased expression of TP53 protein | CTD | PMID:25895606 |
Tp53 | Rat | erythromycin estolate | decreases expression | EXP | | 6480464 | Erythromycin Estolate results in decreased expression of TP53 mRNA | CTD | PMID:17522070 |
Tp53 | Rat | erythrosin B | increases activity | ISO | RGD:70502 | 6480464 | Erythrosine results in increased activity of TP53 protein | CTD | PMID:9168006 |
Tp53 | Rat | esculetin | increases degradation | ISO | RGD:70502 | 6480464 | esculetin results in increased degradation of TP53 protein | CTD | PMID:14634213 |
Tp53 | Rat | esculetin | increases expression | ISO | RGD:70502 | 6480464 | esculetin results in increased expression of TP53 protein | CTD | PMID:31313495 |
Tp53 | Rat | estragole | increases phosphorylation | EXP | | 6480464 | estragole results in increased phosphorylation of TP53 protein | CTD | PMID:29054680 |
Tp53 | Rat | etacrynic acid | affects localization | ISO | RGD:70502 | 6480464 | Ethacrynic Acid affects the localization of TP53 protein | CTD | PMID:25817893 |
Tp53 | Rat | ethacridine | affects activity | ISO | RGD:70502 | 6480464 | Ethacridine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | ethanol | multiple interactions | EXP | | 6480464 | [2,4-dichlorophenoxyacetic acid isooctyl ester results in increased abundance of 2,4-Dichlorophenoxyacetic Acid] promotes the reaction [Ethanol more ... | CTD | PMID:12003908|PMID:24146112|PMID:24769256|PMID:28115068|PMID:30844427|PMID:33314588|PMID:36085217 |
Tp53 | Rat | ethanol | multiple interactions | ISO | RGD:70502 | 6480464 | Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 more ... | CTD | PMID:29803612 |
Tp53 | Rat | ethanol | increases acetylation | EXP | | 6480464 | Ethanol results in increased acetylation of TP53 protein | CTD | PMID:24769256 |
Tp53 | Rat | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of TP53 mRNA; Ethanol results in increased expression of TP53 more ... | CTD | PMID:23273579|PMID:24146112|PMID:29769550|PMID:30844427|PMID:33314588|PMID:36085217 |
Tp53 | Rat | ethanol | increases expression | ISO | RGD:11440 | 6480464 | Ethanol results in increased expression of TP53 mRNA; Ethanol results in increased expression of TRP53 more ... | CTD | PMID:24146112|PMID:28849987|PMID:37271273 |
Tp53 | Rat | ethanol | multiple interactions | ISO | RGD:11440 | 6480464 | [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with more ... | CTD | PMID:24146112|PMID:27270636|PMID:28849987|PMID:37271273 |
Tp53 | Rat | ethidium | affects activity | ISO | RGD:70502 | 6480464 | Ethidium affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | ethion | affects activity | ISO | RGD:70502 | 6480464 | ethion metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | ethyl 4-nitrophenyl ethylphosphonate | affects activity | ISO | RGD:70502 | 6480464 | Armin metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Ethyl acrylate | increases expression | ISO | RGD:11440 | 6480464 | ethyl acrylate results in increased expression of TRP53 protein | CTD | PMID:9667752 |
Tp53 | Rat | Ethyl icosapentate | multiple interactions | EXP | | 6480464 | eicosapentaenoic acid ethyl ester inhibits the reaction [Methotrexate results in increased expression of TP53 protein] | CTD | PMID:37450014 |
Tp53 | Rat | ethylenediaminetetraacetic acid | multiple interactions | ISO | RGD:70502 | 6480464 | Edetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP53 protein] inhibits more ... | CTD | PMID:25446071 |
Tp53 | Rat | etomoxir | increases expression | EXP | | 6480464 | etomoxir results in increased expression of TP53 mRNA | CTD | PMID:19234235 |
Tp53 | Rat | etoposide | multiple interactions | ISO | RGD:70502 | 6480464 | 2,4,4'-trichlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 2,4,5,2',5'-pentachlorobiphenyl inhibits the more ... | CTD | PMID:11895857|PMID:15964798|PMID:16882877|PMID:18698031|PMID:19751709|PMID:20299546|PMID:20623183|PMID:21801448|PMID:23144690|PMID:23396362|PMID:24067374|PMID:25078064|PMID:25699604|PMID:25744307|PMID:26259609|PMID:27129209|PMID:27358234|PMID:27982581|PMID:29471073|PMID:30177839|PMID:37956312|PMID:9815696 |
Tp53 | Rat | etoposide | affects activity | ISO | RGD:70502 | 6480464 | Etoposide affects the activity of TP53 protein; Etoposide metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | etoposide | increases activity | ISO | RGD:70502 | 6480464 | Etoposide results in increased activity of TP53 protein | CTD | PMID:16120219|PMID:20655369|PMID:22010212|PMID:30818834 |
Tp53 | Rat | etoposide | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Etoposide | CTD | PMID:20477944 |
Tp53 | Rat | etoposide | increases phosphorylation | ISO | RGD:70502 | 6480464 | Etoposide results in increased phosphorylation of TP53 protein | CTD | PMID:21801448|PMID:23144690|PMID:25744307 |
Tp53 | Rat | etoposide | increases expression | ISO | RGD:70502 | 6480464 | [Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 more ... | CTD | PMID:11895857|PMID:12082016|PMID:15131059|PMID:16120219|PMID:19751709|PMID:21212465|PMID:23396362|PMID:27129209|PMID:27358234|PMID:27982581|PMID:29471073|PMID:31542801 |
Tp53 | Rat | etoposide | increases expression | EXP | | 6480464 | Etoposide results in increased expression of TP53 protein | CTD | PMID:17516866|PMID:23690541 |
Tp53 | Rat | etoposide | multiple interactions | EXP | | 6480464 | cordycepin promotes the reaction [Etoposide results in increased expression of TP53 protein]; Etoposide promotes the more ... | CTD | PMID:15459018|PMID:16330492|PMID:17516866|PMID:23690541 |
Tp53 | Rat | etoposide | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Etoposide; TP53 results in increased susceptibility to Etoposide | CTD | PMID:16882877|PMID:21552291|PMID:29471073 |
Tp53 | Rat | etoposide | increases acetylation | ISO | RGD:70502 | 6480464 | Etoposide results in increased acetylation of TP53 protein; Etoposide results in increased acetylation of TP53 more ... | CTD | PMID:20299546|PMID:27129209 |
Tp53 | Rat | etoposide | multiple interactions | ISO | RGD:11440 | 6480464 | [CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the more ... | CTD | PMID:21526190|PMID:22003191|PMID:22242153|PMID:24067374 |
Tp53 | Rat | etoposide | increases expression | ISO | RGD:11440 | 6480464 | Etoposide results in increased expression of TRP53 protein | CTD | PMID:21526190 |
Tp53 | Rat | eugenol | multiple interactions | EXP | | 6480464 | Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TP53 protein] | CTD | PMID:19851710 |
Tp53 | Rat | eugenol | increases mutagenesis | ISO | RGD:70502 | 6480464 | Eugenol results in increased mutagenesis of TP53 gene | CTD | PMID:15576237 |
Tp53 | Rat | eugenol | increases expression | ISO | RGD:11440 | 6480464 | Eugenol results in increased expression of TRP53 mRNA; Eugenol results in increased expression of TRP53 more ... | CTD | PMID:20537511 |
Tp53 | Rat | eugenol | multiple interactions | ISO | RGD:11440 | 6480464 | Eugenol promotes the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein] | CTD | PMID:20043298 |
Tp53 | Rat | EUK-134 | multiple interactions | ISO | RGD:70502 | 6480464 | EUK-134 inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]; EUK-134 inhibits more ... | CTD | PMID:25005833 |
Tp53 | Rat | eurycomanone | decreases expression | ISO | RGD:70502 | 6480464 | eurycomanone results in decreased expression of TP53 protein | CTD | PMID:21903368 |
Tp53 | Rat | Evodiamine | increases expression | ISO | RGD:70502 | 6480464 | evodiamine results in increased expression of TP53 protein | CTD | PMID:32057900 |
Tp53 | Rat | Evodiamine | multiple interactions | ISO | RGD:70502 | 6480464 | XMU-MP-1 inhibits the reaction [evodiamine results in increased expression of TP53 protein] | CTD | PMID:32057900 |
Tp53 | Rat | famphur | affects activity | ISO | RGD:70502 | 6480464 | famophos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | fenamiphos | affects activity | ISO | RGD:70502 | 6480464 | fenamiphos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | fenbendazole | increases expression | EXP | | 6480464 | Fenbendazole results in increased expression of TP53 protein | CTD | PMID:23411599 |
Tp53 | Rat | fenbendazole | increases expression | ISO | RGD:70502 | 6480464 | Fenbendazole analog results in increased expression of TP53 protein; Fenbendazole results in increased expression of more ... | CTD | PMID:35569513 |
Tp53 | Rat | fenitrothion | multiple interactions | EXP | | 6480464 | [Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [Fenitrothion results in more ... | CTD | PMID:31173782|PMID:33393722|PMID:33439051|PMID:34968465 |
Tp53 | Rat | fenitrothion | affects activity | ISO | RGD:70502 | 6480464 | Fenitrothion metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | fenitrothion | increases expression | EXP | | 6480464 | Fenitrothion results in increased expression of TP53 mRNA; Fenitrothion results in increased expression of TP53 more ... | CTD | PMID:31173782|PMID:33393722|PMID:33439051|PMID:34968465 |
Tp53 | Rat | fenofibrate | increases expression | EXP | | 6480464 | Fenofibrate results in increased expression of TP53 mRNA | CTD | PMID:17264098 |
Tp53 | Rat | fenofibrate | affects activity | ISO | RGD:70502 | 6480464 | Fenofibrate affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | fenofibrate | affects activity | EXP | | 6480464 | Fenofibrate affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | fenpropathrin | increases expression | EXP | | 6480464 | fenpropathrin results in increased expression of TP53 mRNA | CTD | PMID:38369055 |
Tp53 | Rat | fenpropathrin | multiple interactions | EXP | | 6480464 | Curcumin inhibits the reaction [fenpropathrin results in increased expression of TP53 mRNA] | CTD | PMID:38369055 |
Tp53 | Rat | fenpyroximate | increases expression | ISO | RGD:70502 | 6480464 | fenpyroximate results in increased expression of TP53 mRNA | CTD | PMID:36933581 |
Tp53 | Rat | fensulfothion | affects activity | ISO | RGD:70502 | 6480464 | fensulfothion metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | fenthion | increases expression | ISO | RGD:11440 | 6480464 | Fenthion results in increased expression of TRP53 mRNA | CTD | PMID:34813904 |
Tp53 | Rat | fenthion | affects activity | ISO | RGD:70502 | 6480464 | Fenthion metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | fenticlor | affects activity | ISO | RGD:70502 | 6480464 | fentichlor affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | fentin acetate | affects activity | ISO | RGD:70502 | 6480464 | phentin acetate affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of TP53 mRNA; fenvalerate results in increased expression of TP53 more ... | CTD | PMID:33656234 |
Tp53 | Rat | ferric ammonium citrate | increases expression | ISO | RGD:70502 | 6480464 | ferric ammonium citrate results in increased expression of TP53 protein | CTD | PMID:38483099 |
Tp53 | Rat | ferric ammonium citrate | increases expression | EXP | | 6480464 | ferric ammonium citrate results in increased expression of TP53 protein | CTD | PMID:38483099 |
Tp53 | Rat | ferric oxide | multiple interactions | EXP | | 6480464 | [ferric oxide analog co-treated with Acrolein] results in increased expression of TP53 protein | CTD | PMID:24847785 |
Tp53 | Rat | ferric oxide | increases phosphorylation | EXP | | 6480464 | ferric oxide analog results in increased phosphorylation of TP53 protein | CTD | PMID:22995439 |
Tp53 | Rat | ferrosoferric oxide | multiple interactions | ISO | RGD:70502 | 6480464 | [Ferrosoferric Oxide binds to titanium dioxide] which results in increased expression of TP53 protein | CTD | PMID:30098274 |
Tp53 | Rat | ferrostatin-1 | multiple interactions | EXP | | 6480464 | ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TP53 protein]; ferrostatin-1 inhibits the more ... | CTD | PMID:33737050|PMID:35101590 |
Tp53 | Rat | finasteride | multiple interactions | EXP | | 6480464 | Finasteride inhibits the reaction [Dietary Fats results in increased expression of TP53 protein]; Finasteride inhibits more ... | CTD | PMID:39265715 |
Tp53 | Rat | fingolimod hydrochloride | increases phosphorylation | ISO | RGD:70502 | 6480464 | Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein | CTD | PMID:25939952 |
Tp53 | Rat | fingolimod hydrochloride | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein]; necrostatin-1 inhibits more ... | CTD | PMID:25939952 |
Tp53 | Rat | fipronil | affects localization | ISO | RGD:70502 | 6480464 | fipronil affects the localization of TP53 protein | CTD | PMID:21296133 |
Tp53 | Rat | fisetin | multiple interactions | ISO | RGD:70502 | 6480464 | [Cisplatin co-treated with fisetin] affects the localization of TP53 protein; [Cisplatin co-treated with fisetin] results more ... | CTD | PMID:21216935|PMID:22931364 |
Tp53 | Rat | fisetin | multiple interactions | EXP | | 6480464 | fisetin inhibits the reaction [Cisplatin results in increased expression of TP53 protein] | CTD | PMID:25184746 |
Tp53 | Rat | fisetin | affects localization | ISO | RGD:70502 | 6480464 | fisetin affects the localization of TP53 protein | CTD | PMID:21216935 |
Tp53 | Rat | fisetin | increases expression | ISO | RGD:70502 | 6480464 | fisetin results in increased expression of TP53 protein | CTD | PMID:21216935 |
Tp53 | Rat | flavanone | multiple interactions | ISO | RGD:70502 | 6480464 | flavanone results in increased expression of and results in increased phosphorylation of TP53 protein | CTD | PMID:22056764 |
Tp53 | Rat | flavanones | increases expression | ISO | RGD:70502 | 6480464 | Flavanones results in increased expression of TP53 protein | CTD | PMID:21616090 |
Tp53 | Rat | flavanones | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in decreased susceptibility to Flavanones | CTD | PMID:21616090 |
Tp53 | Rat | flavanones | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 gene mutant form promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]; more ... | CTD | PMID:21616090 |
Tp53 | Rat | flavonoids | increases activity | ISO | RGD:70502 | 6480464 | Flavonoids results in increased activity of TP53 protein | CTD | PMID:12082016 |
Tp53 | Rat | floxuridine | increases expression | ISO | RGD:70502 | 6480464 | Floxuridine results in increased expression of TP53 protein | CTD | PMID:19015155 |
Tp53 | Rat | floxuridine | affects activity | ISO | RGD:70502 | 6480464 | Floxuridine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | fluazinam | increases expression | ISO | RGD:70502 | 6480464 | fluazinam results in increased expression of TP53 protein | CTD | PMID:21907236 |
Tp53 | Rat | flubendazole | increases activity | ISO | RGD:70502 | 6480464 | flubendazole results in increased activity of TP53 protein | CTD | PMID:32652169 |
Tp53 | Rat | flucytosine | increases expression | ISO | RGD:70502 | 6480464 | Flucytosine results in increased expression of TP53 protein | CTD | PMID:15592511 |
Tp53 | Rat | flumethrin | increases expression | ISO | RGD:70502 | 6480464 | flumethrin results in increased expression of TP53 mRNA | CTD | PMID:34142587 |
Tp53 | Rat | fluoranthene | multiple interactions | ISO | RGD:11440 | 6480464 | fluoranthene promotes the reaction [Benzo(a)pyrene results in increased expression of TRP53 mRNA]; fluoranthene promotes the more ... | CTD | PMID:22120587 |
Tp53 | Rat | fluoranthene | increases expression | ISO | RGD:11440 | 6480464 | fluoranthene results in increased expression of TRP53 protein | CTD | PMID:22120587 |
Tp53 | Rat | fluoranthene | multiple interactions | ISO | RGD:70502 | 6480464 | fluoranthene promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein] | CTD | PMID:22120587 |
Tp53 | Rat | fluorometholone | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Fluorometholone inhibits the reaction [Glucose results in increased expression of TP53 more ... | CTD | PMID:35264022 |
Tp53 | Rat | fluoxetine | increases expression | ISO | RGD:11440 | 6480464 | Fluoxetine results in increased expression of TRP53 mRNA | CTD | PMID:21497159 |
Tp53 | Rat | fluoxetine | increases expression | ISO | RGD:70502 | 6480464 | Fluoxetine results in increased expression of TP53 mRNA | CTD | PMID:18836303 |
Tp53 | Rat | flurbiprofen | multiple interactions | ISO | RGD:70502 | 6480464 | Flurbiprofen results in increased abundance of and results in increased phosphorylation of TP53 protein | CTD | PMID:15710360 |
Tp53 | Rat | flurbiprofen | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Flurbiprofen | CTD | PMID:15710360 |
Tp53 | Rat | flurbiprofen | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein mutant form results in decreased susceptibility to Flurbiprofen | CTD | PMID:15710360 |
Tp53 | Rat | flurbiprofen | increases expression | ISO | RGD:70502 | 6480464 | Flurbiprofen results in increased expression of TP53 protein | CTD | PMID:11687965 |
Tp53 | Rat | flusalan | affects activity | ISO | RGD:70502 | 6480464 | fluorophene affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of TP53 mRNA | CTD | PMID:24136188 |
Tp53 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of TP53 mRNA | CTD | PMID:24793618 |
Tp53 | Rat | folic acid | affects methylation | EXP | | 6480464 | Folic Acid affects the methylation of TP53 protein | CTD | PMID:17056795 |
Tp53 | Rat | folic acid | increases expression | ISO | RGD:70502 | 6480464 | Folic Acid results in increased expression of TP53 protein | CTD | PMID:26056802 |
Tp53 | Rat | folic acid | decreases expression | ISO | RGD:11440 | 6480464 | Folic Acid results in decreased expression of TRP53 mRNA | CTD | PMID:25629700 |
Tp53 | Rat | folic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [Folic Acid co-treated with Methyl Methanesulfonate] results in decreased expression of TP53 mRNA; AG 1879 more ... | CTD | PMID:22183962|PMID:26056802|PMID:27113042|PMID:29250709|PMID:30581319 |
Tp53 | Rat | folic acid | affects expression | ISO | RGD:70502 | 6480464 | Folic Acid affects the expression of TP53 mRNA; Folic Acid affects the expression of TP53 more ... | CTD | PMID:16361273|PMID:16611376 |
Tp53 | Rat | folic acid | multiple interactions | ISO | RGD:11440 | 6480464 | [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization more ... | CTD | PMID:16112698|PMID:25559736|PMID:28471487 |
Tp53 | Rat | folic acid | multiple interactions | EXP | | 6480464 | [Folic Acid co-treated with Isoflavones] results in decreased expression of TP53 protein; Folic Acid inhibits more ... | CTD | PMID:20060418|PMID:8863662 |
Tp53 | Rat | fonofos | affects activity | ISO | RGD:70502 | 6480464 | Fonofos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | formaldehyde | increases expression | ISO | RGD:70502 | 6480464 | Formaldehyde results in increased expression of TP53 mRNA; Formaldehyde results in increased expression of TP53 more ... | CTD | PMID:15715472|PMID:22525295 |
Tp53 | Rat | formaldehyde | decreases expression | ISO | RGD:70502 | 6480464 | Formaldehyde results in decreased expression of TP53 protein | CTD | PMID:26400731 |
Tp53 | Rat | formaldehyde | increases expression | EXP | | 6480464 | Formaldehyde results in increased expression of TP53 protein | CTD | PMID:39142364 |
Tp53 | Rat | formaldehyde | multiple interactions | EXP | | 6480464 | Fish Oils inhibits the reaction [Formaldehyde results in increased expression of TP53 protein] | CTD | PMID:39142364 |
Tp53 | Rat | formic acid | multiple interactions | ISO | RGD:70502 | 6480464 | formic acid inhibits the reaction [sodium bichromate results in increased expression of TP53 protein] | CTD | PMID:10942736 |
Tp53 | Rat | formononetin | multiple interactions | EXP | | 6480464 | formononetin inhibits the reaction [Cisplatin results in increased expression of TP53 protein] | CTD | PMID:28414026 |
Tp53 | Rat | formononetin | decreases expression | ISO | RGD:70502 | 6480464 | formononetin results in decreased expression of TP53 protein | CTD | PMID:28414026 |
Tp53 | Rat | formononetin | multiple interactions | ISO | RGD:70502 | 6480464 | XI-006 inhibits the reaction [formononetin results in decreased expression of TP53 protein] | CTD | PMID:28414026 |
Tp53 | Rat | fosthiazate | affects activity | ISO | RGD:70502 | 6480464 | fosthiazate metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | fostriecin | multiple interactions | ISO | RGD:70502 | 6480464 | fostriecin promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 more ... | CTD | PMID:24954032 |
Tp53 | Rat | fotemustine | increases expression | ISO | RGD:70502 | 6480464 | fotemustine results in increased expression of TP53 protein; fotemustine results in increased expression of TP53 more ... | CTD | PMID:25125662 |
Tp53 | Rat | fotemustine | multiple interactions | ISO | RGD:70502 | 6480464 | fotemustine promotes the reaction [TP53 protein binds to POLH promoter] | CTD | PMID:25125662 |
Tp53 | Rat | fructose | multiple interactions | ISO | RGD:11440 | 6480464 | [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with more ... | CTD | PMID:37271273 |
Tp53 | Rat | fulvestrant | multiple interactions | ISO | RGD:70502 | 6480464 | Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of TP53 protein]; Fulvestrant inhibits more ... | CTD | PMID:15870704|PMID:29383186 |
Tp53 | Rat | fulvestrant | decreases expression | ISO | RGD:70502 | 6480464 | fulvestrant results in decreased expression of TP53 protein | CTD | PMID:24169358 |
Tp53 | Rat | fumaraldehyde | decreases expression | ISO | RGD:70502 | 6480464 | malealdehyde results in decreased expression of TP53 mRNA | CTD | PMID:35750087 |
Tp53 | Rat | fumonisin B1 | multiple interactions | ISO | RGD:70502 | 6480464 | [fumonisin B1 results in decreased chemical synthesis of Ceramides] which affects the splicing of and more ... | CTD | PMID:25195822 |
Tp53 | Rat | fumonisin B1 | decreases expression | ISO | RGD:70502 | 6480464 | fumonisin B1 results in decreased expression of TP53 mRNA | CTD | PMID:27757495 |
Tp53 | Rat | fumonisin B1 | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression more ... | CTD | PMID:28181396 |
Tp53 | Rat | fumonisin B1 | increases expression | EXP | | 6480464 | fumonisin B1 results in increased expression of TP53 protein | CTD | PMID:28181396 |
Tp53 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of TP53 gene | CTD | PMID:22079235 |
Tp53 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TP53 protein | CTD | PMID:20124500 |
Tp53 | Rat | Fusarenone X | increases expression | ISO | RGD:11440 | 6480464 | fusarenon-X results in increased expression of TRP53 mRNA | CTD | PMID:24983900 |
Tp53 | Rat | Fusaric acid | affects phosphorylation | ISO | RGD:11440 | 6480464 | Fusaric Acid affects the phosphorylation of TRP53 protein | CTD | PMID:32156565 |
Tp53 | Rat | galactose | increases expression | ISO | RGD:70502 | 6480464 | Galactose results in increased expression of TP53 protein | CTD | PMID:23036742|PMID:29426000 |
Tp53 | Rat | galactose | increases expression | EXP | | 6480464 | Galactose results in increased expression of TP53 protein | CTD | PMID:39265715 |
Tp53 | Rat | galactose | multiple interactions | EXP | | 6480464 | [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in more ... | CTD | PMID:25997894|PMID:39265715 |
Tp53 | Rat | galactose | multiple interactions | ISO | RGD:70502 | 6480464 | Phycocyanin inhibits the reaction [Galactose results in increased expression of TP53 protein] | CTD | PMID:23036742 |
Tp53 | Rat | gallic acid | decreases expression | ISO | RGD:70502 | 6480464 | Gallic Acid results in decreased expression of TP53 mRNA | CTD | PMID:21887735 |
Tp53 | Rat | gallic acid | increases expression | ISO | RGD:70502 | 6480464 | Gallic Acid results in increased expression of TP53 mRNA; Gallic Acid results in increased expression more ... | CTD | PMID:33002289 |
Tp53 | Rat | gallic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [Carboplatin co-treated with Gallic Acid] results in increased expression of TP53 protein; [Gallic Acid co-treated more ... | CTD | PMID:33002289 |
Tp53 | Rat | gamma-hexachlorocyclohexane | multiple interactions | ISO | RGD:70502 | 6480464 | [Hexachlorocyclohexane co-treated with Estradiol] results in increased expression of TP53 protein | CTD | PMID:18174961 |
Tp53 | Rat | gamma-tocopherol | increases activity | ISO | RGD:70502 | 6480464 | Tocopherols results in increased activity of TP53 protein | CTD | PMID:15883045 |
Tp53 | Rat | ganciclovir | increases expression | ISO | RGD:70502 | 6480464 | Ganciclovir results in increased expression of TP53 protein | CTD | PMID:15592511 |
Tp53 | Rat | gefitinib | multiple interactions | ISO | RGD:70502 | 6480464 | [TP53 protein results in decreased expression of AURKA protein] which results in increased susceptibility to more ... | CTD | PMID:21216229|PMID:29383186 |
Tp53 | Rat | gefitinib | increases expression | EXP | | 6480464 | gefitinib results in increased expression of TP53 mRNA; gefitinib results in increased expression of TP53 more ... | CTD | PMID:27084042 |
Tp53 | Rat | gefitinib | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to gefitinib | CTD | PMID:21216229 |
Tp53 | Rat | geldanamycin | affects localization | ISO | RGD:70502 | 6480464 | geldanamycin affects the localization of TP53 protein | CTD | PMID:17293044 |
Tp53 | Rat | geldanamycin | affects expression | ISO | RGD:70502 | 6480464 | geldanamycin affects the expression of TP53 protein | CTD | PMID:24211270 |
Tp53 | Rat | geldanamycin | multiple interactions | ISO | RGD:70502 | 6480464 | Tretinoin inhibits the reaction [geldanamycin affects the localization of TP53 protein] | CTD | PMID:17293044 |
Tp53 | Rat | gemcitabine | affects activity | ISO | RGD:70502 | 6480464 | Gemcitabine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | gemcitabine | multiple interactions | ISO | RGD:70502 | 6480464 | [TFAP2A protein co-treated with TP53 gene mutant form] results in decreased susceptibility to Gemcitabine; Nicotine more ... | CTD | PMID:16601104|PMID:21489314 |
Tp53 | Rat | gemcitabine | increases expression | ISO | RGD:70502 | 6480464 | Gemcitabine results in increased expression of TP53 protein | CTD | PMID:12082016|PMID:16601104|PMID:17671697 |
Tp53 | Rat | Geniposide | multiple interactions | ISO | RGD:70502 | 6480464 | geniposide inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]; geniposide inhibits more ... | CTD | PMID:37940031 |
Tp53 | Rat | genistein | multiple interactions | ISO | RGD:70502 | 6480464 | [Fluorouracil co-treated with Genistein] results in increased expression of TP53 mRNA; [Genistein co-treated with trichostatin more ... | CTD | PMID:15177039|PMID:15896711|PMID:22626855|PMID:26768552 |
Tp53 | Rat | genistein | multiple interactions | EXP | | 6480464 | [Genistein co-treated with vinclozolin] results in decreased expression of TP53 mRNA | CTD | PMID:32827888 |
Tp53 | Rat | genistein | decreases expression | ISO | RGD:11440 | 6480464 | Genistein results in decreased expression of TRP53 mRNA | CTD | PMID:31593742 |
Tp53 | Rat | genistein | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Genistein | CTD | PMID:26768552 |
Tp53 | Rat | genistein | increases expression | ISO | RGD:70502 | 6480464 | Genistein results in increased expression of TP53 protein | CTD | PMID:19800779 |
Tp53 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TP53 mRNA; Gentamicins results in increased expression of TP53 more ... | CTD | PMID:22061828|PMID:31628940 |
Tp53 | Rat | gentamycin | multiple interactions | EXP | | 6480464 | Celecoxib inhibits the reaction [Gentamicins results in increased expression of TP53 protein] | CTD | PMID:31628940 |
Tp53 | Rat | gentamycin | increases expression | ISO | RGD:70502 | 6480464 | Gentamicins results in increased expression of TP53 mRNA | CTD | PMID:29992668 |
Tp53 | Rat | geraniol | multiple interactions | EXP | | 6480464 | geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 more ... | CTD | PMID:21907755 |
Tp53 | Rat | geraniol | increases expression | ISO | RGD:70502 | 6480464 | geraniol results in increased expression of TP53 mRNA | CTD | PMID:27683099 |
Tp53 | Rat | gingerol | increases expression | ISO | RGD:70502 | 6480464 | gingerol results in increased expression of TP53 protein | CTD | PMID:18030663|PMID:25034532 |
Tp53 | Rat | gingerol | multiple interactions | ISO | RGD:11440 | 6480464 | gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the more ... | CTD | PMID:18030663|PMID:37121058 |
Tp53 | Rat | gingerol | multiple interactions | ISO | RGD:70502 | 6480464 | [gingerol results in increased expression of TP53 protein] which results in increased susceptibility to TNFSF10 more ... | CTD | PMID:18030663|PMID:25034532|PMID:28988496 |
Tp53 | Rat | ginkgolide B | multiple interactions | ISO | RGD:11440 | 6480464 | ginkgolide B inhibits the reaction [Cisplatin promotes the reaction [TRP53 protein binds to NOX4 promoter]]; more ... | CTD | PMID:26768586 |
Tp53 | Rat | ginsenoside Rg1 | multiple interactions | ISO | RGD:70502 | 6480464 | ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of TP53 mRNA] | CTD | PMID:34783124 |
Tp53 | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of TP53 mRNA | CTD | PMID:24136188 |
Tp53 | Rat | gliclazide | increases expression | ISO | RGD:70502 | 6480464 | Gliclazide results in increased expression of TP53 mRNA | CTD | PMID:33652124 |
Tp53 | Rat | glimepiride | increases expression | ISO | RGD:70502 | 6480464 | glimepiride results in increased expression of TP53 mRNA | CTD | PMID:33652124 |
Tp53 | Rat | glucaric acid | multiple interactions | ISO | RGD:11440 | 6480464 | [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in more ... | CTD | PMID:25478867 |
Tp53 | Rat | glucose | affects localization | ISO | RGD:70502 | 6480464 | Glucose affects the localization of TP53 protein | CTD | PMID:24218232 |
Tp53 | Rat | glucose | increases expression | EXP | | 6480464 | Glucose results in increased expression of TP53 protein | CTD | PMID:38483099 |
Tp53 | Rat | glucose | multiple interactions | ISO | RGD:11440 | 6480464 | [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of TRP53 protein; [Oxygen deficiency more ... | CTD | PMID:28675767 |
Tp53 | Rat | glucose | increases expression | ISO | RGD:70502 | 6480464 | Glucose results in increased expression of TP53 mRNA; Glucose results in increased expression of TP53 more ... | CTD | PMID:26188290|PMID:27049278|PMID:35264022|PMID:38000455|PMID:38483099 |
Tp53 | Rat | glucose | multiple interactions | EXP | | 6480464 | [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in more ... | CTD | PMID:23451161|PMID:25997894 |
Tp53 | Rat | glucose | increases acetylation | ISO | RGD:70502 | 6480464 | Glucose results in increased acetylation of TP53 protein | CTD | PMID:20068143 |
Tp53 | Rat | glucose | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytic Acid inhibits the reaction [Glucose results in increased expression of more ... | CTD | PMID:20068143|PMID:21548882|PMID:24218232|PMID:24451382|PMID:26188290|PMID:27049278|PMID:33962019|PMID:35264022|PMID:38000455 |
Tp53 | Rat | glutaraldehyde | decreases expression | ISO | RGD:70502 | 6480464 | Glutaral results in decreased expression of TP53 mRNA | CTD | PMID:28236482 |
Tp53 | Rat | glutathione | multiple interactions | ISO | RGD:70502 | 6480464 | [Buthionine Sulfoximine results in decreased abundance of Glutathione] inhibits the reaction [Benzo(a)pyrene results in increased more ... | CTD | PMID:12807757|PMID:17555331|PMID:19202565|PMID:22927544|PMID:27634759 |
Tp53 | Rat | glutathione | increases glutathionylation | ISO | RGD:70502 | 6480464 | Glutathione results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | glutathione | decreases abundance | ISO | RGD:70502 | 6480464 | TP53 protein results in decreased abundance of Glutathione | CTD | PMID:12967322 |
Tp53 | Rat | glutathione | increases expression | ISO | RGD:70502 | 6480464 | Glutathione results in increased expression of TP53 protein | CTD | PMID:10897038 |
Tp53 | Rat | glutathione disulfide | multiple interactions | ISO | RGD:70502 | 6480464 | Dithiothreitol inhibits the reaction [Glutathione Disulfide results in increased glutathionylation of TP53 protein]; Glutathione Disulfide more ... | CTD | PMID:15993333|PMID:17555331 |
Tp53 | Rat | glutathione disulfide | increases glutathionylation | ISO | RGD:70502 | 6480464 | Glutathione Disulfide results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | Glutathione ethyl ester | multiple interactions | ISO | RGD:70502 | 6480464 | S-ethyl glutathione inhibits the reaction [Camptothecin results in increased expression of TP53 protein modified form]; more ... | CTD | PMID:17555331 |
Tp53 | Rat | glyburide | multiple interactions | EXP | | 6480464 | Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA]; Glyburide inhibits the more ... | CTD | PMID:30817903|PMID:33387473 |
Tp53 | Rat | glyburide | increases expression | ISO | RGD:70502 | 6480464 | Glyburide results in increased expression of TP53 mRNA | CTD | PMID:33652124 |
Tp53 | Rat | glycerol | increases activity | ISO | RGD:70502 | 6480464 | Glycerol results in increased activity of TP53 protein mutant form | CTD | PMID:15975526 |
Tp53 | Rat | glycine betaine | multiple interactions | EXP | | 6480464 | Betaine inhibits the reaction [Doxorubicin results in increased phosphorylation of TP53 protein] | CTD | PMID:38651543 |
Tp53 | Rat | glycitein | increases expression | ISO | RGD:70502 | 6480464 | glycitein results in increased expression of TP53 protein | CTD | PMID:19800779 |
Tp53 | Rat | glycoursodeoxycholic acid | multiple interactions | EXP | | 6480464 | glycoursodeoxycholic acid inhibits the reaction [TP53 protein results in increased expression of BAX mRNA] | CTD | PMID:17881359 |
Tp53 | Rat | glycyrrhetinate | decreases expression | EXP | | 6480464 | Glycyrrhetinic Acid results in decreased expression of TP53 protein | CTD | PMID:38348715 |
Tp53 | Rat | glycyrrhetinic acid | decreases expression | EXP | | 6480464 | Glycyrrhetinic Acid results in decreased expression of TP53 protein | CTD | PMID:38348715 |
Tp53 | Rat | glycyrrhizinic acid | increases expression | ISO | RGD:70502 | 6480464 | Glycyrrhizic Acid results in increased expression of TP53 mRNA | CTD | PMID:35844403 |
Tp53 | Rat | glyphosate | increases expression | ISO | RGD:70502 | 6480464 | Glyphosate results in increased expression of TP53 mRNA | CTD | PMID:31874349 |
Tp53 | Rat | glyphosate | decreases expression | ISO | RGD:70502 | 6480464 | Glyphosate results in decreased expression of TP53 mRNA | CTD | PMID:31751608 |
Tp53 | Rat | glyphosate | multiple interactions | ISO | RGD:70502 | 6480464 | [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to more ... | CTD | PMID:32800223 |
Tp53 | Rat | glyphosate | increases activity | ISO | RGD:11440 | 6480464 | Glyphosate results in increased activity of TRP53 protein | CTD | PMID:22634143 |
Tp53 | Rat | glyphosate | increases methylation | ISO | RGD:70502 | 6480464 | Glyphosate results in increased methylation of TP53 promoter | CTD | PMID:31751608 |
Tp53 | Rat | gold atom | increases expression | ISO | RGD:11440 | 6480464 | Gold analog results in increased expression of TRP53 mRNA | CTD | PMID:22486372 |
Tp53 | Rat | gold(0) | increases expression | ISO | RGD:11440 | 6480464 | Gold analog results in increased expression of TRP53 mRNA | CTD | PMID:22486372 |
Tp53 | Rat | Goserelin | decreases expression | ISO | RGD:70502 | 6480464 | Goserelin results in decreased expression of TP53 protein | CTD | PMID:16973256 |
Tp53 | Rat | gossypol | multiple interactions | ISO | RGD:11440 | 6480464 | [gossypol acetic acid results in increased abundance of Gossypol] promotes the reaction [ponatinib results in more ... | CTD | PMID:34699866 |
Tp53 | Rat | graphene oxide | decreases expression | ISO | RGD:70502 | 6480464 | graphene oxide results in decreased expression of TP53 protein | CTD | PMID:33219560 |
Tp53 | Rat | graphene oxide | increases expression | ISO | RGD:70502 | 6480464 | graphene oxide results in increased expression of TP53 mRNA | CTD | PMID:33219560|PMID:33219585 |
Tp53 | Rat | guggulsterone | multiple interactions | ISO | RGD:70502 | 6480464 | KL protein affects the reaction [pregna-4,17-diene-3,16-dione inhibits the reaction [Oxygen deficiency results in increased expression more ... | CTD | PMID:35123992 |
Tp53 | Rat | GW 4064 | decreases expression | ISO | RGD:70502 | 6480464 | GW 4064 results in decreased expression of TP53 mRNA; GW 4064 results in decreased expression more ... | CTD | PMID:28496032 |
Tp53 | Rat | GW 6471 | multiple interactions | EXP | | 6480464 | GW 6471 inhibits the reaction [SIRT6 protein inhibits the reaction [Doxorubicin results in increased expression more ... | CTD | PMID:38395252 |
Tp53 | Rat | Gyrophoric acid | decreases expression | ISO | RGD:70502 | 6480464 | gyrophoric acid results in decreased expression of TP53 protein | CTD | PMID:22285236 |
Tp53 | Rat | haloperidol | increases expression | EXP | | 6480464 | Haloperidol results in increased expression of TP53 mRNA; Haloperidol results in increased expression of TP53 more ... | CTD | PMID:16462815 |
Tp53 | Rat | harmalol | increases expression | ISO | RGD:70502 | 6480464 | harmalol results in increased expression of TP53 mRNA; harmalol results in increased expression of TP53 more ... | CTD | PMID:27590872 |
Tp53 | Rat | heparin | decreases expression | ISO | RGD:70502 | 6480464 | Heparin analog results in decreased expression of TP53 protein | CTD | PMID:20201787 |
Tp53 | Rat | heptachlor | decreases expression | ISO | RGD:70502 | 6480464 | Heptachlor results in decreased expression of TP53 protein | CTD | PMID:9544696 |
Tp53 | Rat | hesperetin | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [hesperetin results in increased expression of TP53 protein]; hesperetin inhibits the more ... | CTD | PMID:15795422|PMID:37487865 |
Tp53 | Rat | hesperetin | increases expression | ISO | RGD:70502 | 6480464 | hesperetin results in increased expression of TP53 protein | CTD | PMID:37487865 |
Tp53 | Rat | hesperidin | multiple interactions | EXP | | 6480464 | Hesperidin inhibits the reaction [sodium arsenite results in increased expression of TP53 protein] | CTD | PMID:30066062 |
Tp53 | Rat | hexachlorophene | affects activity | ISO | RGD:70502 | 6480464 | Hexachlorophene affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | hexadecanoic acid | multiple interactions | ISO | RGD:70502 | 6480464 | 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased more ... | CTD | PMID:24451382|PMID:32369900 |
Tp53 | Rat | hexanal | decreases expression | ISO | RGD:70502 | 6480464 | n-hexanal results in decreased expression of TP53 mRNA | CTD | PMID:12921975 |
Tp53 | Rat | homocysteine | increases phosphorylation | EXP | | 6480464 | Homocysteine results in increased phosphorylation of TP53 protein | CTD | PMID:13679428 |
Tp53 | Rat | homocysteine | multiple interactions | ISO | RGD:70502 | 6480464 | Folic Acid affects the reaction [Homocysteine affects the expression of TP53 mRNA]; Folic Acid affects more ... | CTD | PMID:29250709 |
Tp53 | Rat | homocysteine | affects expression | ISO | RGD:70502 | 6480464 | Homocysteine affects the expression of TP53 mRNA; Homocysteine affects the expression of TP53 protein | CTD | PMID:29250709 |
Tp53 | Rat | hycanthone | affects activity | ISO | RGD:70502 | 6480464 | Hycanthone affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | hydralazine | multiple interactions | ISO | RGD:70502 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of TP53 mRNA | CTD | PMID:17183730 |
Tp53 | Rat | hydralazine | increases activity | ISO | RGD:70502 | 6480464 | Hydralazine results in increased activity of TP53 protein | CTD | PMID:12082016 |
Tp53 | Rat | hydrogen peroxide | multiple interactions | ISO | RGD:70502 | 6480464 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Hydrogen Peroxide promotes the reaction [Resveratrol results in increased phosphorylation of more ... | CTD | PMID:10531375|PMID:15081873|PMID:15795422|PMID:18681908|PMID:21552291|PMID:23639522|PMID:23859249|PMID:24067374|PMID:24451382|PMID:24933654|PMID:24967384|PMID:25005833|PMID:25108166|PMID:27049278|PMID:28526263|PMID:29110037|PMID:29185360|PMID:30139380|PMID:30265530|PMID:32980322|PMID:35759867|PMID:36567042|PMID:37940031|PMID:8943236|PMID:9535218 |
Tp53 | Rat | hydrogen peroxide | increases expression | ISO | RGD:11440 | 158013773 | hydrogen peroxide increases expression of Trp53 protein in C-kit+ cardiac progenitor cells | RGD | |
Tp53 | Rat | hydrogen peroxide | multiple interactions | ISO | RGD:11440 | 158013773 | melatonin inhibits the reaction [hydrogen peroxide increases expression of Trp53 protein in C-kit+ cardiac progenitor more ... | RGD | |
Tp53 | Rat | hydrogen peroxide | multiple interactions | EXP | | 6480464 | 2-(4-((dimethylamino)methyl)benzylidene)-5,6-dimethoxy-2,3-dihydroinden-1-one inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]; donepezil inhibits more ... | CTD | PMID:12414117|PMID:12642403|PMID:14689451|PMID:16647178|PMID:19345205|PMID:20041988|PMID:27525270 |
Tp53 | Rat | hydrogen peroxide | increases expression | EXP | | 6480464 | Hydrogen Peroxide results in increased expression of TP53 mRNA; Hydrogen Peroxide results in increased expression more ... | CTD | PMID:12414117|PMID:12642403|PMID:14689451|PMID:16647178|PMID:19345205|PMID:20041988|PMID:27525270 |
Tp53 | Rat | hydrogen peroxide | increases acetylation | ISO | RGD:11440 | 6480464 | Hydrogen Peroxide results in increased acetylation of TRP53 protein | CTD | PMID:25512378 |
Tp53 | Rat | hydrogen peroxide | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Hydrogen Peroxide | CTD | PMID:20477944 |
Tp53 | Rat | hydrogen peroxide | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in decreased susceptibility to Hydrogen Peroxide | CTD | PMID:21552291|PMID:24067374 |
Tp53 | Rat | hydrogen peroxide | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Hydrogen Peroxide | CTD | PMID:17301063 |
Tp53 | Rat | hydrogen peroxide | increases acetylation | ISO | RGD:70502 | 6480464 | Hydrogen Peroxide results in increased acetylation of TP53 protein | CTD | PMID:18681908|PMID:30139380 |
Tp53 | Rat | hydrogen peroxide | decreases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein results in decreased susceptibility to Hydrogen Peroxide | CTD | PMID:21552291 |
Tp53 | Rat | hydrogen peroxide | increases expression | ISO | RGD:11440 | 6480464 | Hydrogen Peroxide results in increased expression of TRP53; Hydrogen Peroxide results in increased expression of more ... | CTD | PMID:21552291|PMID:21705337|PMID:25242411 |
Tp53 | Rat | hydrogen peroxide | increases phosphorylation | ISO | RGD:11440 | 6480464 | Hydrogen Peroxide results in increased phosphorylation of TRP53 | CTD | PMID:21552291 |
Tp53 | Rat | hydrogen peroxide | multiple interactions | ISO | RGD:11440 | 6480464 | CAV1 gene mutant form inhibits the reaction [Hydrogen Peroxide results in increased acetylation of TRP53 more ... | CTD | PMID:10922372|PMID:21552291|PMID:21705337|PMID:25242411|PMID:25512378 |
Tp53 | Rat | hydrogen peroxide | increases phosphorylation | ISO | RGD:70502 | 6480464 | Hydrogen Peroxide results in increased phosphorylation of TP53; Hydrogen Peroxide results in increased phosphorylation of more ... | CTD | PMID:21552291|PMID:24933654 |
Tp53 | Rat | hydrogen peroxide | increases glutathionylation | ISO | RGD:70502 | 6480464 | Hydrogen Peroxide results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | hydrogen peroxide | increases expression | ISO | RGD:70502 | 6480464 | [Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of more ... | CTD | PMID:11964141|PMID:15081873|PMID:21454520|PMID:21552291|PMID:23639522|PMID:23859249|PMID:24967384|PMID:25005833|PMID:25108166|PMID:27049278|PMID:29185360|PMID:29486183|PMID:30265530|PMID:32980322|PMID:33709623|PMID:35759867|PMID:36567042|PMID:36796651|PMID:37940031|PMID:9535218|PMID:9989825 |
Tp53 | Rat | hydrogen peroxide | increases activity | ISO | RGD:70502 | 6480464 | Hydrogen Peroxide results in increased activity of TP53 protein | CTD | PMID:15242773 |
Tp53 | Rat | hydrogen peroxide | decreases expression | ISO | RGD:70502 | 6480464 | Hydrogen Peroxide results in decreased expression of TP53 mRNA | CTD | PMID:12419474 |
Tp53 | Rat | hydroquinone | increases expression | ISO | RGD:70502 | 6480464 | hydroquinone results in increased expression of TP53 protein; hydroquinone results in increased expression of TRP53 more ... | CTD | PMID:17875398|PMID:28843007|PMID:35123993|PMID:39029599 |
Tp53 | Rat | hydroquinone | increases expression | ISO | RGD:11440 | 6480464 | hydroquinone results in increased expression of TRP53 protein | CTD | PMID:23940708 |
Tp53 | Rat | hydroquinone | affects expression | ISO | RGD:70502 | 6480464 | hydroquinone affects the expression of TP53 protein | CTD | PMID:27515134 |
Tp53 | Rat | hydroquinone | decreases expression | ISO | RGD:70502 | 6480464 | hydroquinone results in decreased expression of TP53 mRNA; hydroquinone results in decreased expression of TP53 more ... | CTD | PMID:26047893|PMID:27515134|PMID:33771647|PMID:33932074 |
Tp53 | Rat | hydroquinone | multiple interactions | ISO | RGD:70502 | 6480464 | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of TP53 protein]; 2-tert-butylhydroquinone more ... | CTD | PMID:17875398|PMID:28444915|PMID:28843007|PMID:33771647|PMID:33932074|PMID:35123993|PMID:39029599 |
Tp53 | Rat | hydroxamic acid | increases acetylation | ISO | RGD:70502 | 6480464 | Hydroxamic Acids analog results in increased acetylation of TP53 protein | CTD | PMID:19084294 |
Tp53 | Rat | hydroxychloroquine | multiple interactions | ISO | RGD:70502 | 6480464 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Hydroxychloroquine results in increased expression of TP53 protein]; [Hydroxychloroquine co-treated with more ... | CTD | PMID:38311193 |
Tp53 | Rat | hydroxyurea | increases expression | ISO | RGD:70502 | 6480464 | Hydroxyurea results in increased expression of TP53 protein; Hydroxyurea results in increased expression of TP53 more ... | CTD | PMID:10978678|PMID:16005713|PMID:21840268|PMID:25125662 |
Tp53 | Rat | hydroxyurea | increases phosphorylation | ISO | RGD:70502 | 6480464 | Hydroxyurea results in increased phosphorylation of TP53 protein | CTD | PMID:32466334 |
Tp53 | Rat | hydroxyurea | multiple interactions | ISO | RGD:11440 | 6480464 | Hydroxyurea results in increased expression of and results in increased phosphorylation of TRP53 protein; Hydroxyurea more ... | CTD | PMID:16356682|PMID:27208086|PMID:29228353 |
Tp53 | Rat | hydroxyurea | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 affects the susceptibility to Hydroxyurea | CTD | PMID:29228353 |
Tp53 | Rat | ibuprofen | affects activity | ISO | RGD:70502 | 6480464 | Ibuprofen affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | icariin | increases expression | ISO | RGD:11440 | 6480464 | icariin results in increased expression of TRP53 mRNA; icariin results in increased expression of TRP53 more ... | CTD | PMID:15878162 |
Tp53 | Rat | Icaritin | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [icaritin results in increased phosphorylation of TP53 protein]; icaritin results in more ... | CTD | PMID:38431053 |
Tp53 | Rat | ICI D1694 | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the reaction [raltitrexed results in increased expression of FAS protein]; TP53 protein more ... | CTD | PMID:15161716|PMID:16204068 |
Tp53 | Rat | ICI D1694 | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to raltitrexed | CTD | PMID:17339891 |
Tp53 | Rat | ICI-164384 | multiple interactions | ISO | RGD:70502 | 6480464 | ICI 164384 inhibits the reaction [bisphenol A results in increased expression of TP53 protein]; ICI more ... | CTD | PMID:31681507 |
Tp53 | Rat | idarubicin | multiple interactions | ISO | RGD:11440 | 6480464 | Dexrazoxane inhibits the reaction [Idarubicin results in increased expression of TRP53 mRNA] | CTD | PMID:28973540 |
Tp53 | Rat | idarubicin | increases expression | ISO | RGD:11440 | 6480464 | Idarubicin results in increased expression of TRP53 mRNA | CTD | PMID:28973540 |
Tp53 | Rat | ifosfamide | affects activity | ISO | RGD:70502 | 6480464 | Ifosfamide affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | ifosfamide | multiple interactions | EXP | | 6480464 | morin inhibits the reaction [Ifosfamide results in increased expression of TP53 protein] | CTD | PMID:31722249 |
Tp53 | Rat | ifosfamide | increases expression | EXP | | 6480464 | Ifosfamide results in increased expression of TP53 protein | CTD | PMID:31722249 |
Tp53 | Rat | indole-3-methanol | decreases expression | ISO | RGD:70502 | 6480464 | indole-3-carbinol results in decreased expression of TP53 protein | CTD | PMID:29992829 |
Tp53 | Rat | indole-3-methanol | multiple interactions | ISO | RGD:70502 | 6480464 | indole-3-carbinol results in increased expression of and results in increased phosphorylation of TP53 protein | CTD | PMID:34085558 |
Tp53 | Rat | indometacin | increases expression | ISO | RGD:70502 | 6480464 | Indomethacin results in increased expression of TP53 mRNA; Indomethacin results in increased expression of TP53 more ... | CTD | PMID:10403534|PMID:11260862|PMID:29027214 |
Tp53 | Rat | indometacin | increases expression | EXP | | 6480464 | Indomethacin results in increased expression of TP53 mRNA | CTD | PMID:29027214|PMID:36868495 |
Tp53 | Rat | Inotodiol | increases expression | ISO | RGD:70502 | 6480464 | inotodiol results in increased expression of TP53 protein | CTD | PMID:21359924 |
Tp53 | Rat | Inotodiol | multiple interactions | ISO | RGD:70502 | 6480464 | inotodiol inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA] | CTD | PMID:35759867 |
Tp53 | Rat | inuviscolide | multiple interactions | ISO | RGD:70502 | 6480464 | Caffeine inhibits the reaction [inuviscolide results in increased phosphorylation of TP53 protein]; inuviscolide results in more ... | CTD | PMID:17919456 |
Tp53 | Rat | Iodofenphos | affects activity | ISO | RGD:70502 | 6480464 | iodofenphos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | iohexol | increases expression | ISO | RGD:70502 | 6480464 | Iohexol results in increased expression of TP53 mRNA | CTD | PMID:29705293 |
Tp53 | Rat | iopamidol | increases expression | ISO | RGD:70502 | 6480464 | Iopamidol results in increased expression of TP53 mRNA | CTD | PMID:29705293 |
Tp53 | Rat | irinotecan | increases expression | ISO | RGD:70502 | 6480464 | Irinotecan results in increased expression of TP53 mRNA; Irinotecan results in increased expression of TP53 more ... | CTD | PMID:16963839|PMID:22510560|PMID:22898888 |
Tp53 | Rat | irinotecan | affects activity | ISO | RGD:70502 | 6480464 | Irinotecan affects the activity of TP53 protein; Irinotecan metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | irinotecan | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Irinotecan | CTD | PMID:16963839 |
Tp53 | Rat | irinotecan | increases phosphorylation | ISO | RGD:70502 | 6480464 | Irinotecan results in increased phosphorylation of TP53 protein | CTD | PMID:22510560 |
Tp53 | Rat | irinotecan | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 results in increased susceptibility to Irinotecan | CTD | PMID:22898888 |
Tp53 | Rat | irinotecan | multiple interactions | ISO | RGD:70502 | 6480464 | [Irinotecan co-treated with Bortezomib] results in increased ubiquitination of TP53 protein; Irinotecan results in increased more ... | CTD | PMID:16204068|PMID:16373703|PMID:16963839|PMID:22898888 |
Tp53 | Rat | iron(III) nitrilotriacetate | multiple interactions | EXP | | 6480464 | [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA; [ferric nitrilotriacetate co-treated more ... | CTD | PMID:21907755 |
Tp53 | Rat | isatin | multiple interactions | ISO | RGD:70502 | 6480464 | [Copper binds to Isatin binds to 2-(2-aminoethyl)pyridine] which results in increased expression of TP53 protein; more ... | CTD | PMID:17327230 |
Tp53 | Rat | Isazofos | affects activity | ISO | RGD:70502 | 6480464 | isazophos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | isocarbophos | affects activity | ISO | RGD:70502 | 6480464 | isocarbophos affects the activity of TP53 protein; isocarbophos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | isocyanates | increases expression | ISO | RGD:70502 | 6480464 | Isocyanates results in increased expression of TP53 protein | CTD | PMID:19283680 |
Tp53 | Rat | isofenphos | affects activity | ISO | RGD:70502 | 6480464 | isofenphos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | isoflavones | multiple interactions | EXP | | 6480464 | [Folic Acid co-treated with Isoflavones] results in decreased expression of TP53 protein | CTD | PMID:20060418 |
Tp53 | Rat | isoflurane | decreases expression | EXP | | 6480464 | Isoflurane results in decreased expression of TP53 mRNA | CTD | PMID:16978161 |
Tp53 | Rat | isoliquiritigenin | increases expression | ISO | RGD:11440 | 6480464 | isoliquiritigenin results in increased expression of TRP53 mRNA | CTD | PMID:27702603 |
Tp53 | Rat | isoprenaline | increases expression | EXP | | 6480464 | Isoproterenol results in increased expression of TP53 protein | CTD | PMID:19466570 |
Tp53 | Rat | isoprenaline | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation more ... | CTD | PMID:32924446 |
Tp53 | Rat | isoprenaline | decreases expression | ISO | RGD:70502 | 6480464 | Isoproterenol results in decreased expression of TP53 mRNA | CTD | PMID:24286936 |
Tp53 | Rat | isoprenaline | increases expression | ISO | RGD:70502 | 6480464 | Isoproterenol results in increased expression of TP53 mRNA | CTD | PMID:24286936 |
Tp53 | Rat | isoprocarb | affects activity | ISO | RGD:70502 | 6480464 | isoprocarb metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | isotretinoin | increases expression | ISO | RGD:11440 | 6480464 | Isotretinoin results in increased expression of TRP53 | CTD | PMID:18652567 |
Tp53 | Rat | isovitexin | increases expression | ISO | RGD:70502 | 6480464 | isovitexin results in increased expression of TP53 mRNA; isovitexin results in increased expression of TP53 more ... | CTD | PMID:37939611 |
Tp53 | Rat | ivermectin | multiple interactions | ISO | RGD:70502 | 6480464 | Ivermectin inhibits the reaction [geranylgeranic acid affects the localization of TP53 protein mutant form] | CTD | PMID:24658405 |
Tp53 | Rat | juglone | multiple interactions | ISO | RGD:70502 | 6480464 | [juglone co-treated with Ascorbic Acid] results in increased phosphorylation of TP53 protein | CTD | PMID:29992683 |
Tp53 | Rat | kaempferol | multiple interactions | ISO | RGD:70502 | 6480464 | Caffeine inhibits the reaction [kaempferol results in increased phosphorylation of TP53 protein]; TP53 protein affects more ... | CTD | PMID:19028473 |
Tp53 | Rat | kaempferol | decreases expression | ISO | RGD:70502 | 6480464 | kaempferol results in decreased expression of TP53 protein | CTD | PMID:37115092 |
Tp53 | Rat | kaempferol | multiple interactions | EXP | | 6480464 | kaempferol inhibits the reaction [Doxorubicin promotes the reaction [TP53 protein binds to BAX promoter]]; kaempferol more ... | CTD | PMID:22155320 |
Tp53 | Rat | kaempferol | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to kaempferol | CTD | PMID:19028473 |
Tp53 | Rat | kaempferol | increases phosphorylation | ISO | RGD:70502 | 6480464 | kaempferol results in increased phosphorylation of TP53 protein | CTD | PMID:19028473 |
Tp53 | Rat | kaempferol | increases expression | ISO | RGD:70502 | 6480464 | kaempferol results in increased expression of TP53 protein | CTD | PMID:19028473 |
Tp53 | Rat | kainic acid | increases expression | EXP | | 6480464 | Kainic Acid results in increased expression of TP53 protein | CTD | PMID:20955365 |
Tp53 | Rat | ketamine | increases expression | ISO | RGD:70502 | 6480464 | Ketamine results in increased expression of TP53 protein | CTD | PMID:19919587 |
Tp53 | Rat | keto-D-fructose 1,6-bisphosphate | increases expression | ISO | RGD:70502 | 6480464 | fructose-1,6-diphosphate results in increased expression of TP53 protein | CTD | PMID:33078453 |
Tp53 | Rat | kojic acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA | CTD | PMID:18544905 |
Tp53 | Rat | kojic acid | multiple interactions | ISO | RGD:11440 | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of TRP53 more ... | CTD | PMID:17917374 |
Tp53 | Rat | kresoxim-methyl | increases activity | ISO | RGD:70502 | 6480464 | kresoxim-methyl results in increased activity of TP53 protein | CTD | PMID:30818834 |
Tp53 | Rat | L-1,4-dithiothreitol | multiple interactions | ISO | RGD:70502 | 6480464 | Dithiothreitol inhibits the reaction [[Cadmium Chloride results in decreased activity of TP53 protein] inhibits the more ... | CTD | PMID:17555331|PMID:25446071 |
Tp53 | Rat | L-ascorbic acid | multiple interactions | EXP | | 6480464 | Ascorbic Acid inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]; Ascorbic more ... | CTD | PMID:20067818|PMID:21262251 |
Tp53 | Rat | L-ascorbic acid | multiple interactions | ISO | RGD:11440 | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of TRP53 more ... | CTD | PMID:17917374|PMID:32632975 |
Tp53 | Rat | L-ascorbic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of more ... | CTD | PMID:20067818|PMID:20530418|PMID:21429301|PMID:22245848|PMID:25977998|PMID:29992683|PMID:31388677 |
Tp53 | Rat | lactacystin | multiple interactions | EXP | | 6480464 | lactacystin inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]; lactacystin results in more ... | CTD | PMID:16330492|PMID:18463101 |
Tp53 | Rat | lactacystin | increases ubiquitination | EXP | | 6480464 | lactacystin results in increased ubiquitination of TP53 protein | CTD | PMID:18463101 |
Tp53 | Rat | lactucin | increases expression | ISO | RGD:70502 | 6480464 | lactucin results in increased expression of TP53 protein | CTD | PMID:36364182 |
Tp53 | Rat | lanreotide | multiple interactions | EXP | | 6480464 | lanreotide inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 mRNA] | CTD | PMID:19874807 |
Tp53 | Rat | lansoprazole | multiple interactions | EXP | | 6480464 | Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of TP53 mRNA] | CTD | PMID:28412091 |
Tp53 | Rat | lapachol | affects activity | ISO | RGD:70502 | 6480464 | lapachol affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | lead diacetate | decreases expression | ISO | RGD:70502 | 6480464 | lead acetate results in decreased expression of TP53 mRNA | CTD | PMID:38568856 |
Tp53 | Rat | lead diacetate | multiple interactions | EXP | | 6480464 | [lead acetate results in increased abundance of Lead] which results in increased expression of TP53 more ... | CTD | PMID:39276841 |
Tp53 | Rat | lead nitrate | multiple interactions | ISO | RGD:70502 | 6480464 | [lead nitrate results in increased abundance of Lead] which results in increased expression of TP53 more ... | CTD | PMID:30738203|PMID:31682781 |
Tp53 | Rat | lead nitrate | increases expression | ISO | RGD:70502 | 6480464 | lead nitrate results in increased expression of TP53 mRNA | CTD | PMID:31682781 |
Tp53 | Rat | lead(0) | decreases expression | ISO | RGD:70502 | 6480464 | Lead results in decreased expression of TP53 mRNA | CTD | PMID:19921347 |
Tp53 | Rat | lead(0) | increases expression | EXP | | 6480464 | Lead results in increased expression of TP53 protein | CTD | PMID:29630945 |
Tp53 | Rat | lead(0) | multiple interactions | EXP | | 6480464 | [lead acetate results in increased abundance of Lead] which results in increased expression of TP53 more ... | CTD | PMID:29630945|PMID:39276841 |
Tp53 | Rat | lead(0) | increases expression | ISO | RGD:70502 | 6480464 | Lead results in increased expression of TP53 protein | CTD | PMID:22610977|PMID:32976933 |
Tp53 | Rat | lead(0) | multiple interactions | ISO | RGD:70502 | 6480464 | [Lead co-treated with APP protein modified form] results in increased expression of TP53 protein; [lead more ... | CTD | PMID:22610977|PMID:30738203 |
Tp53 | Rat | leptomycin B | multiple interactions | ISO | RGD:70502 | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [leptomycin B results in increased expression of TP53 protein]; [leptomycin B more ... | CTD | PMID:15625077|PMID:16467109|PMID:19010883|PMID:19751709|PMID:20803015|PMID:21454520|PMID:24792400|PMID:31645432 |
Tp53 | Rat | leptomycin B | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in increased susceptibility to leptomycin B | CTD | PMID:20803015 |
Tp53 | Rat | leptomycin B | increases expression | ISO | RGD:70502 | 6480464 | leptomycin B results in increased expression of TP53 protein | CTD | PMID:16467109|PMID:19751709 |
Tp53 | Rat | leptomycin B | multiple interactions | EXP | | 6480464 | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [leptomycin B results in increased expression of more ... | CTD | PMID:15459018 |
Tp53 | Rat | leptomycin B | increases expression | EXP | | 6480464 | leptomycin B results in increased expression of TP53 protein | CTD | PMID:15459018 |
Tp53 | Rat | leptomycin B | affects expression | EXP | | 6480464 | leptomycin B affects the expression of TP53 protein | CTD | PMID:11751435 |
Tp53 | Rat | leptomycin B | decreases degradation | ISO | RGD:70502 | 6480464 | leptomycin B results in decreased degradation of TP53 protein | CTD | PMID:15625077 |
Tp53 | Rat | leptophos | affects activity | ISO | RGD:70502 | 6480464 | Leptophos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | levamisole | decreases expression | ISO | RGD:70502 | 6480464 | Levamisole results in decreased expression of TP53 mRNA; Levamisole results in decreased expression of TP53 more ... | CTD | PMID:11139434 |
Tp53 | Rat | levetiracetam | increases activity | EXP | | 6480464 | Levetiracetam results in increased activity of TP53 protein | CTD | PMID:37098359 |
Tp53 | Rat | levetiracetam | multiple interactions | EXP | | 6480464 | Quercetin inhibits the reaction [Levetiracetam results in increased activity of TP53 protein] | CTD | PMID:37098359 |
Tp53 | Rat | lidocaine | affects expression | ISO | RGD:11440 | 6480464 | Lidocaine affects the expression of TRP53 mRNA | CTD | PMID:18931217 |
Tp53 | Rat | lidocaine | decreases expression | EXP | | 6480464 | Lidocaine results in decreased expression of TP53 mRNA | CTD | PMID:35283115 |
Tp53 | Rat | limonene | increases expression | ISO | RGD:70502 | 6480464 | limonene results in increased expression of TP53 protein | CTD | PMID:12921557 |
Tp53 | Rat | linalool | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 results in increased susceptibility to linalool | CTD | PMID:19922762 |
Tp53 | Rat | linalool | increases expression | ISO | RGD:70502 | 6480464 | linalool results in increased expression of TP53 mRNA; linalool results in increased expression of TP53 more ... | CTD | PMID:19922762|PMID:26703569 |
Tp53 | Rat | lipoic acid | multiple interactions | EXP | | 6480464 | Thioctic Acid inhibits the reaction [Methotrexate results in increased expression of TP53 protein] | CTD | PMID:19900424 |
Tp53 | Rat | lipopolysaccharide | increases expression | EXP | | 6480464 | Lipopolysaccharides results in increased expression of TP53 mRNA; Lipopolysaccharides results in increased expression of TP53 more ... | CTD | PMID:30084861|PMID:9409811 |
Tp53 | Rat | lipopolysaccharide | increases expression | ISO | RGD:70502 | 6480464 | Lipopolysaccharides results in increased expression of TP53 protein | CTD | PMID:32329368 |
Tp53 | Rat | lipopolysaccharide | multiple interactions | ISO | RGD:70502 | 6480464 | MIR22 inhibits the reaction [Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of TP53 more ... | CTD | PMID:32329368 |
Tp53 | Rat | lipopolysaccharide | increases expression | ISO | RGD:11440 | 6480464 | Lipopolysaccharides results in increased expression of TRP53 mRNA; Lipopolysaccharides results in increased expression of TRP53 more ... | CTD | PMID:18550754|PMID:23170834 |
Tp53 | Rat | lipopolysaccharide | multiple interactions | ISO | RGD:11440 | 6480464 | [Lipopolysaccharides co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of TRP53 mRNA; [Lipopolysaccharides co-treated with more ... | CTD | PMID:10205001|PMID:18550754|PMID:23107598|PMID:23170834|PMID:33865415 |
Tp53 | Rat | lipopolysaccharide | multiple interactions | EXP | | 6480464 | pifithrin inhibits the reaction [Lipopolysaccharides results in increased localization of TP53 protein] | CTD | PMID:12665479 |
Tp53 | Rat | lipopolysaccharide | increases localization | EXP | | 6480464 | Lipopolysaccharides results in increased localization of TP53 protein | CTD | PMID:12665479 |
Tp53 | Rat | lithium atom | multiple interactions | ISO | RGD:70502 | 6480464 | Lithium inhibits the reaction [GSK3B protein binds to TP53 protein]; Lithium inhibits the reaction [sodium more ... | CTD | PMID:15475000|PMID:17849503 |
Tp53 | Rat | lithium atom | multiple interactions | ISO | RGD:11440 | 6480464 | TP53 affects the reaction [Lithium results in increased expression of CDKN1A protein] | CTD | PMID:11337498 |
Tp53 | Rat | lithium chloride | increases expression | ISO | RGD:70502 | 6480464 | Lithium Chloride results in increased expression of TP53 protein | CTD | PMID:17210701 |
Tp53 | Rat | lithium chloride | multiple interactions | ISO | RGD:11440 | 6480464 | Lithium Chloride results in decreased degradation of and results in increased expression of TRP53 protein | CTD | PMID:16055726 |
Tp53 | Rat | lithium hydride | multiple interactions | ISO | RGD:11440 | 6480464 | TP53 affects the reaction [Lithium results in increased expression of CDKN1A protein] | CTD | PMID:11337498 |
Tp53 | Rat | lithium hydride | multiple interactions | ISO | RGD:70502 | 6480464 | Lithium inhibits the reaction [GSK3B protein binds to TP53 protein]; Lithium inhibits the reaction [sodium more ... | CTD | PMID:15475000|PMID:17849503 |
Tp53 | Rat | Lobetyolin | decreases phosphorylation | ISO | RGD:70502 | 6480464 | lobetyolin results in decreased phosphorylation of TP53 protein | CTD | PMID:34075790 |
Tp53 | Rat | losartan | affects expression | EXP | | 6480464 | Losartan affects the expression of TP53 protein | CTD | PMID:22000973 |
Tp53 | Rat | lovastatin | multiple interactions | ISO | RGD:70502 | 6480464 | Lovastatin inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]; Lovastatin results in more ... | CTD | PMID:17088865|PMID:21199873 |
Tp53 | Rat | lovastatin | multiple interactions | EXP | | 6480464 | Lovastatin inhibits the reaction [Cisplatin results in increased expression of TP53 protein modified form] | CTD | PMID:26739623 |
Tp53 | Rat | lovastatin | increases expression | ISO | RGD:70502 | 6480464 | Lovastatin results in increased expression of TP53 mRNA | CTD | PMID:21199873 |
Tp53 | Rat | lupeol | multiple interactions | ISO | RGD:70502 | 6480464 | lupeol inhibits the reaction [mancozeb results in increased expression of TP53 mRNA] | CTD | PMID:27235710 |
Tp53 | Rat | luteolin | multiple interactions | ISO | RGD:11440 | 6480464 | Fluorouracil promotes the reaction [Luteolin results in increased expression of TRP53 protein]; Luteolin inhibits the more ... | CTD | PMID:23770416|PMID:31288002 |
Tp53 | Rat | luteolin | decreases expression | ISO | RGD:11440 | 6480464 | Luteolin results in decreased expression of TRP53 mRNA | CTD | PMID:36819991 |
Tp53 | Rat | luteolin | increases expression | ISO | RGD:11440 | 6480464 | Luteolin results in increased expression of TRP53 protein | CTD | PMID:31288002 |
Tp53 | Rat | luteolin | multiple interactions | EXP | | 6480464 | Luteolin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]; Luteolin inhibits more ... | CTD | PMID:27525270|PMID:32035215 |
Tp53 | Rat | luteolin | increases expression | EXP | | 6480464 | Luteolin results in increased expression of TP53 mRNA | CTD | PMID:31201582 |
Tp53 | Rat | luzindole | multiple interactions | ISO | RGD:11440 | 158013773 | luzindole inhibits the reaction [melatonin inhibits the reaction [hydrogen peroxide increases expression of Trp53 protein more ... | RGD | |
Tp53 | Rat | LY294002 | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of more ... | CTD | PMID:15763944|PMID:16024610|PMID:17534123|PMID:20856197|PMID:26942697|PMID:30265530|PMID:32687844|PMID:35264022 |
Tp53 | Rat | LY294002 | multiple interactions | EXP | | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Deferoxamine results in increased activity of TP53 protein] which results in more ... | CTD | PMID:19950214 |
Tp53 | Rat | LY294002 | increases phosphorylation | ISO | RGD:70502 | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of TP53 protein | CTD | PMID:25305377 |
Tp53 | Rat | LY294002 | increases expression | ISO | RGD:70502 | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of TP53 mRNA; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of TP53 more ... | CTD | PMID:15001399|PMID:34677630 |
Tp53 | Rat | lycopene | decreases expression | ISO | RGD:70502 | 6480464 | lycopene results in decreased expression of TP53 mRNA | CTD | PMID:16886892 |
Tp53 | Rat | lycopene | multiple interactions | ISO | RGD:11440 | 6480464 | Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TP53 mRNA] | CTD | PMID:36583613 |
Tp53 | Rat | lysophosphatidylcholine | multiple interactions | ISO | RGD:11440 | 6480464 | [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance more ... | CTD | PMID:30258081 |
Tp53 | Rat | lysophosphatidylethanolamine | multiple interactions | ISO | RGD:11440 | 6480464 | [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance more ... | CTD | PMID:30258081 |
Tp53 | Rat | maculosin | multiple interactions | ISO | RGD:11440 | 6480464 | maculosin inhibits the reaction [Diethylnitrosamine results in decreased expression of TRP53 mRNA]; maculosin inhibits the more ... | CTD | PMID:34726822 |
Tp53 | Rat | magnesium dichloride | affects expression | EXP | | 6480464 | Magnesium Chloride affects the expression of TP53 mRNA | CTD | PMID:10506531 |
Tp53 | Rat | magnesium oxide | multiple interactions | ISO | RGD:70502 | 6480464 | [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression more ... | CTD | PMID:27920530 |
Tp53 | Rat | malathion | multiple interactions | ISO | RGD:70502 | 6480464 | Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein] | CTD | PMID:12762645 |
Tp53 | Rat | malathion | multiple interactions | ISO | RGD:11440 | 6480464 | Plant Extracts inhibits the reaction [Malathion results in increased expression of TRP53 protein]; Polyphenols inhibits more ... | CTD | PMID:32120800 |
Tp53 | Rat | malathion | multiple interactions | EXP | | 6480464 | [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 more ... | CTD | PMID:21628957 |
Tp53 | Rat | malathion | increases expression | EXP | | 6480464 | Malathion results in increased expression of TP53 mRNA | CTD | PMID:21628957 |
Tp53 | Rat | malathion | increases expression | ISO | RGD:11440 | 6480464 | Malathion results in increased expression of TRP53 protein | CTD | PMID:12505448|PMID:32120800 |
Tp53 | Rat | malathion | increases expression | ISO | RGD:70502 | 6480464 | Malathion results in increased expression of TP53 mRNA; Malathion results in increased expression of TP53 more ... | CTD | PMID:12762645|PMID:18204794|PMID:19787260 |
Tp53 | Rat | maleimide | multiple interactions | ISO | RGD:70502 | 6480464 | maleimide analog binds to and results in increased activity of TP53 protein mutant form | CTD | PMID:15998635 |
Tp53 | Rat | malonaldehyde | increases mutagenesis | ISO | RGD:70502 | 6480464 | Malondialdehyde results in increased mutagenesis of TP53 gene | CTD | PMID:30658077 |
Tp53 | Rat | mancozeb | decreases expression | ISO | RGD:70502 | 6480464 | mancozeb results in decreased expression of TRP53 mRNA; mancozeb results in decreased expression of TRP53 more ... | CTD | PMID:22369882 |
Tp53 | Rat | mancozeb | multiple interactions | ISO | RGD:70502 | 6480464 | lupeol inhibits the reaction [mancozeb results in increased expression of TP53 mRNA] | CTD | PMID:27235710 |
Tp53 | Rat | mancozeb | increases expression | ISO | RGD:70502 | 6480464 | mancozeb results in increased expression of TP53 mRNA | CTD | PMID:27235710 |
Tp53 | Rat | mancozeb | decreases expression | ISO | RGD:11440 | 6480464 | mancozeb results in decreased expression of TRP53 mRNA; mancozeb results in decreased expression of TRP53 more ... | CTD | PMID:22369882 |
Tp53 | Rat | maneb | multiple interactions | ISO | RGD:11440 | 6480464 | 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TRP53 protein]; more ... | CTD | PMID:20964710|PMID:23963992|PMID:23985028 |
Tp53 | Rat | manganese atom | increases expression | EXP | | 6480464 | Manganese results in increased expression of TP53 mRNA; Manganese results in increased expression of TP53 more ... | CTD | PMID:23997110|PMID:24845367|PMID:25027559|PMID:25448048 |
Tp53 | Rat | manganese atom | increases response to substance | EXP | | 6480464 | TP53 protein results in increased susceptibility to Manganese | CTD | PMID:25791630 |
Tp53 | Rat | manganese atom | multiple interactions | EXP | | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of TP53 more ... | CTD | PMID:25027559|PMID:25448048|PMID:25791630|PMID:30844427|PMID:33314588 |
Tp53 | Rat | manganese(0) | increases expression | EXP | | 6480464 | Manganese results in increased expression of TP53 mRNA; Manganese results in increased expression of TP53 more ... | CTD | PMID:23997110|PMID:24845367|PMID:25027559|PMID:25448048 |
Tp53 | Rat | manganese(0) | increases response to substance | EXP | | 6480464 | TP53 protein results in increased susceptibility to Manganese | CTD | PMID:25791630 |
Tp53 | Rat | manganese(0) | multiple interactions | EXP | | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of TP53 more ... | CTD | PMID:25027559|PMID:25448048|PMID:25791630|PMID:30844427|PMID:33314588 |
Tp53 | Rat | manganese(II) chloride | increases expression | EXP | | 6480464 | manganese chloride results in increased expression of TP53 mRNA | CTD | PMID:17623882 |
Tp53 | Rat | manganese(II) chloride | multiple interactions | EXP | | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of TP53 more ... | CTD | PMID:30844427|PMID:33314588 |
Tp53 | Rat | mangiferin | multiple interactions | EXP | | 6480464 | mangiferin inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein] | CTD | PMID:10657591 |
Tp53 | Rat | masoprocol | multiple interactions | ISO | RGD:70502 | 6480464 | MYC affects the reaction [Masoprocol results in increased expression of TP53 protein] | CTD | PMID:15034932 |
Tp53 | Rat | masoprocol | increases expression | ISO | RGD:70502 | 6480464 | Masoprocol results in increased expression of TP53 protein | CTD | PMID:15034932 |
Tp53 | Rat | mechlorethamine | increases expression | ISO | RGD:70502 | 6480464 | Mechlorethamine results in increased expression of TP53 protein | CTD | PMID:16738803 |
Tp53 | Rat | mechlorethamine | affects binding | ISO | RGD:70502 | 6480464 | Mechlorethamine binds to TP53 protein | CTD | PMID:35312310 |
Tp53 | Rat | mechlorethamine | multiple interactions | ISO | RGD:70502 | 6480464 | Mechlorethamine results in increased expression of and affects the localization of TP53 protein; Mechlorethamine results more ... | CTD | PMID:35312310 |
Tp53 | Rat | mechlorethamine | increases stability | ISO | RGD:70502 | 6480464 | Mechlorethamine results in increased stability of TP53 protein | CTD | PMID:35312310 |
Tp53 | Rat | mechlorethamine | decreases activity | ISO | RGD:70502 | 6480464 | Mechlorethamine results in decreased activity of TP53 protein | CTD | PMID:35312310 |
Tp53 | Rat | mechlorethamine | increases alkylation | ISO | RGD:70502 | 6480464 | Mechlorethamine results in increased alkylation of TP53 protein | CTD | PMID:35312310 |
Tp53 | Rat | mechlorethamine | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 affects the susceptibility to Mechlorethamine; TRP53 protein affects the susceptibility to Mechlorethamine | CTD | PMID:12185594|PMID:23845566 |
Tp53 | Rat | mechlorethamine | multiple interactions | ISO | RGD:11440 | 6480464 | Mechlorethamine results in increased phosphorylation of and results in increased expression of TRP53 protein | CTD | PMID:25891025 |
Tp53 | Rat | medroxyprogesterone acetate | multiple interactions | ISO | RGD:70502 | 6480464 | [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression more ... | CTD | PMID:22534328 |
Tp53 | Rat | meglumine amidotrizoate | increases expression | EXP | | 6480464 | Diatrizoate Meglumine results in increased expression of TP53 mRNA | CTD | PMID:28412091 |
Tp53 | Rat | meglumine amidotrizoate | multiple interactions | EXP | | 6480464 | Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of TP53 mRNA] | CTD | PMID:28412091 |
Tp53 | Rat | MeIQ | increases mutagenesis | ISO | RGD:11440 | 6480464 | 2-amino-3,4-dimethylimidazo(4,5-f)quinoline results in increased mutagenesis of TRP53 exon; 2-amino-3,4-dimethylimidazo(4,5-f)quinoline results in increased mutagenesis of TRP53 more ... | CTD | PMID:7818762|PMID:8844820|PMID:9119951 |
Tp53 | Rat | MeIQx | increases mutagenesis | EXP | | 6480464 | 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased mutagenesis of TP53 gene | CTD | PMID:8844820 |
Tp53 | Rat | MeIQx | increases expression | ISO | RGD:70502 | 6480464 | 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of TP53 protein | CTD | PMID:23810796 |
Tp53 | Rat | melatonin | increases expression | ISO | RGD:70502 | 6480464 | Melatonin results in increased expression of TP53 protein | CTD | PMID:12071473 |
Tp53 | Rat | melatonin | multiple interactions | ISO | RGD:11440 | 6480464 | Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TRP53 mRNA]; more ... | CTD | PMID:20964710|PMID:23963992|PMID:35643323|PMID:36421005|PMID:36633214|PMID:37994397 |
Tp53 | Rat | melatonin | multiple interactions | ISO | RGD:70502 | 6480464 | Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of TP53 mRNA]; more ... | CTD | PMID:24799992|PMID:33962019|PMID:36633214|PMID:38000455 |
Tp53 | Rat | melatonin | multiple interactions | EXP | | 6480464 | Melatonin inhibits the reaction [bisphenol A results in increased expression of TP53 protein]; Melatonin inhibits more ... | CTD | PMID:14993511|PMID:20041988|PMID:25454643 |
Tp53 | Rat | melphalan | affects activity | ISO | RGD:70502 | 6480464 | Melphalan affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | menadione | multiple interactions | ISO | RGD:70502 | 6480464 | [sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of TP53 protein; EUK-134 more ... | CTD | PMID:19082730|PMID:25005833 |
Tp53 | Rat | menadione | affects activity | ISO | RGD:70502 | 6480464 | Vitamin K 3 affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | menadione | increases expression | ISO | RGD:70502 | 6480464 | Vitamin K 3 results in increased expression of TP53 protein | CTD | PMID:21533478|PMID:25005833 |
Tp53 | Rat | mercaptopurine | affects activity | ISO | RGD:70502 | 6480464 | Mercaptopurine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | mercury atom | affects folding | ISO | RGD:11440 | 6480464 | Mercury affects the folding of TRP53 protein | CTD | PMID:8467489 |
Tp53 | Rat | mercury dichloride | increases expression | ISO | RGD:11440 | 6480464 | Mercuric Chloride results in increased expression of TRP53 mRNA | CTD | PMID:23202902 |
Tp53 | Rat | mercury(0) | affects folding | ISO | RGD:11440 | 6480464 | Mercury affects the folding of TRP53 protein | CTD | PMID:8467489 |
Tp53 | Rat | metformin | multiple interactions | ISO | RGD:70502 | 150404268 | Metformin increases expression and phosphorylation of TP53 protein in epithelial cell of alveolus of lung | RGD | |
Tp53 | Rat | metformin | decreases expression | ISO | RGD:70502 | 6480464 | Metformin results in decreased expression of TP53 protein | CTD | PMID:29185360 |
Tp53 | Rat | metformin | multiple interactions | ISO | RGD:70502 | 6480464 | [Hydrogen Peroxide co-treated with Metformin] results in decreased expression of TP53 protein; [Metformin co-treated with more ... | CTD | PMID:29185360|PMID:38479708 |
Tp53 | Rat | metformin | affects activity | EXP | | 6480464 | Metformin affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | methamidophos | affects activity | ISO | RGD:70502 | 6480464 | methamidophos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | methamphetamine | increases expression | ISO | RGD:11440 | 6480464 | Methamphetamine results in increased expression of TRP53 protein; Methamphetamine results in increased expression of TRP53 more ... | CTD | PMID:11457507|PMID:17234339 |
Tp53 | Rat | methamphetamine | multiple interactions | EXP | | 6480464 | Luteolin inhibits the reaction [Methamphetamine results in increased expression of TP53 protein] | CTD | PMID:32035215 |
Tp53 | Rat | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of TP53 protein | CTD | PMID:32035215|PMID:32676729 |
Tp53 | Rat | methamphetamine | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Methamphetamine | CTD | PMID:12050851|PMID:9369336 |
Tp53 | Rat | methamphetamine | multiple interactions | ISO | RGD:11440 | 6480464 | NOS1 protein affects the reaction [Methamphetamine results in increased expression of TRP53 protein]; SOD1 protein more ... | CTD | PMID:11457507|PMID:9369336 |
Tp53 | Rat | methapyrilene | increases expression | EXP | | 6480464 | Methapyrilene results in increased expression of TP53 mRNA | CTD | PMID:26558467 |
Tp53 | Rat | methidathion | increases expression | ISO | RGD:11440 | 6480464 | methidathion results in increased expression of TRP53 mRNA | CTD | PMID:34813904 |
Tp53 | Rat | methoctramine tetrahydrochloride | increases expression | EXP | | 6480464 | methoctramine analog results in increased expression of TP53 protein | CTD | PMID:19576191 |
Tp53 | Rat | methotrexate | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the more ... | CTD | PMID:17637740|PMID:19548002|PMID:21114963|PMID:21624110|PMID:21875941|PMID:22010212|PMID:22183962|PMID:24967384 |
Tp53 | Rat | methotrexate | increases expression | ISO | RGD:11440 | 6480464 | Methotrexate results in increased expression of TRP53 mRNA | CTD | PMID:23836430 |
Tp53 | Rat | methotrexate | increases expression | ISO | RGD:70502 | 6480464 | Methotrexate results in increased expression of TP53 mRNA; Methotrexate results in increased expression of TP53 more ... | CTD | PMID:21624110|PMID:21678067|PMID:22183962|PMID:24967384|PMID:29027214 |
Tp53 | Rat | methotrexate | decreases expression | ISO | RGD:70502 | 6480464 | Methotrexate results in decreased expression of TP53 mRNA | CTD | PMID:17400583|PMID:24449571 |
Tp53 | Rat | methotrexate | decreases response to substance | ISO | RGD:11440 | 6480464 | TRP53 mRNA results in decreased susceptibility to Methotrexate; TRP53 protein results in decreased susceptibility to more ... | CTD | PMID:16918715 |
Tp53 | Rat | methotrexate | multiple interactions | EXP | | 6480464 | eicosapentaenoic acid ethyl ester inhibits the reaction [Methotrexate results in increased expression of TP53 protein]; more ... | CTD | PMID:19900424|PMID:32666843|PMID:35842499|PMID:37450014 |
Tp53 | Rat | methotrexate | increases expression | EXP | | 6480464 | Methotrexate results in increased expression of TP53 mRNA; Methotrexate results in increased expression of TP53 more ... | CTD | PMID:19900424|PMID:29027214|PMID:32666843|PMID:37450014 |
Tp53 | Rat | methotrexate | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 mutant form results in increased susceptibility to Methotrexate; TP53 protein results in increased susceptibility more ... | CTD | PMID:19548002|PMID:21875941 |
Tp53 | Rat | methoxsalen | increases expression | ISO | RGD:70502 | 6480464 | Methoxsalen results in increased expression of TP53 protein | CTD | PMID:22796345 |
Tp53 | Rat | methoxsalen | multiple interactions | ISO | RGD:70502 | 6480464 | Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of TP53 protein modified form] | CTD | PMID:23907605 |
Tp53 | Rat | methoxyacetic acid | multiple interactions | ISO | RGD:70502 | 6480464 | withanone inhibits the reaction [methoxyacetic acid results in increased expression of TP53 protein] | CTD | PMID:21573189 |
Tp53 | Rat | methoxyacetic acid | increases expression | ISO | RGD:70502 | 6480464 | methoxyacetic acid results in increased expression of TP53 protein | CTD | PMID:21573189 |
Tp53 | Rat | methoxychlor | increases phosphorylation | ISO | RGD:70502 | 6480464 | Methoxychlor results in increased phosphorylation of TP53 protein | CTD | PMID:32466334 |
Tp53 | Rat | methyl caffeate | increases expression | ISO | RGD:70502 | 6480464 | methyl caffeate analog results in increased expression of TP53 protein | CTD | PMID:25481497 |
Tp53 | Rat | methyl isocyanate | affects expression | ISO | RGD:70502 | 6480464 | methyl isocyanate affects the expression of TP53 protein | CTD | PMID:19513903 |
Tp53 | Rat | methyl isocyanate | decreases expression | ISO | RGD:11440 | 6480464 | methyl isocyanate results in decreased expression of TRP53 protein | CTD | PMID:22223508 |
Tp53 | Rat | methyl methanesulfonate | multiple interactions | ISO | RGD:70502 | 6480464 | [Folic Acid co-treated with Methyl Methanesulfonate] results in decreased expression of TP53 mRNA; Cadmium Chloride more ... | CTD | PMID:10531375|PMID:17079232|PMID:25078064|PMID:30581319 |
Tp53 | Rat | methyl methanesulfonate | increases expression | ISO | RGD:70502 | 6480464 | Methyl Methanesulfonate results in increased expression of TP53 protein | CTD | PMID:32087850 |
Tp53 | Rat | methyl methanesulfonate | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in increased susceptibility to Methyl Methanesulfonate | CTD | PMID:25595616 |
Tp53 | Rat | methyl methanesulfonate | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 protein affects the reaction [Methyl Methanesulfonate results in increased expression of BTG2 mRNA] | CTD | PMID:22003191 |
Tp53 | Rat | methyl methanesulfonate | increases activity | ISO | RGD:70502 | 6480464 | Methyl Methanesulfonate results in increased activity of TP53 protein | CTD | PMID:20655369 |
Tp53 | Rat | methylarsonic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TP53 more ... | CTD | PMID:23192986 |
Tp53 | Rat | methylene bis(thiocyanate) | affects activity | ISO | RGD:70502 | 6480464 | methylene bis(thiocyanate) affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | methylene blue | affects activity | ISO | RGD:70502 | 6480464 | Methylene Blue affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | methylisothiazolinone | increases expression | ISO | RGD:70502 | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of TP53 protein modified form | CTD | PMID:29110394 |
Tp53 | Rat | methylisothiazolinone | increases phosphorylation | ISO | RGD:70502 | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased phosphorylation of TP53 protein | CTD | PMID:31629900 |
Tp53 | Rat | methylmercury chloride | increases expression | ISO | RGD:11440 | 6480464 | methylmercuric chloride results in increased expression of TRP53 mRNA | CTD | PMID:23202902 |
Tp53 | Rat | methylmercury chloride | decreases expression | ISO | RGD:70502 | 6480464 | methylmercuric chloride results in decreased expression of TP53 mRNA | CTD | PMID:37210002 |
Tp53 | Rat | metiram | multiple interactions | ISO | RGD:70502 | 6480464 | [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to more ... | CTD | PMID:32800223 |
Tp53 | Rat | mevinphos | affects activity | ISO | RGD:70502 | 6480464 | Mevinphos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | microcystin | increases expression | EXP | | 6480464 | Microcystins results in increased expression of TP53 mRNA; Microcystins results in increased expression of TP53 more ... | CTD | PMID:19760617 |
Tp53 | Rat | microcystin RR | increases expression | ISO | RGD:70502 | 6480464 | microcystin RR results in increased expression of TP53 protein | CTD | PMID:19111056 |
Tp53 | Rat | microcystin RR | increases expression | ISO | RGD:11440 | 6480464 | microcystin RR results in increased expression of TRP53 protein | CTD | PMID:20196164 |
Tp53 | Rat | microcystin-LR | increases expression | ISO | RGD:70502 | 6480464 | cyanoginosin LR results in increased expression of TP53; cyanoginosin LR results in increased expression of more ... | CTD | PMID:16624733|PMID:18214937|PMID:20421190|PMID:22539157 |
Tp53 | Rat | microcystin-LR | increases expression | EXP | | 6480464 | cyanoginosin LR results in increased expression of TP53 protein | CTD | PMID:31157505 |
Tp53 | Rat | microcystin-LR | multiple interactions | EXP | | 6480464 | [cyanoginosin LR co-treated with Buthionine Sulfoximine] results in increased expression of TP53 protein; pifithrin inhibits more ... | CTD | PMID:25410294|PMID:31157505 |
Tp53 | Rat | microcystin-LR | increases expression | ISO | RGD:11440 | 6480464 | cyanoginosin LR results in increased expression of TRP53 protein | CTD | PMID:23454832|PMID:28414124 |
Tp53 | Rat | microcystin-LR | increases phosphorylation | ISO | RGD:11440 | 6480464 | cyanoginosin LR results in increased phosphorylation of TRP53 protein | CTD | PMID:23891578 |
Tp53 | Rat | microcystin-LR | increases phosphorylation | ISO | RGD:70502 | 6480464 | cyanoginosin LR results in increased phosphorylation of TP53 protein | CTD | PMID:20421190 |
Tp53 | Rat | midostaurin | multiple interactions | ISO | RGD:70502 | 6480464 | midostaurin affects the reaction [Resveratrol results in increased phosphorylation of and results in increased activity more ... | CTD | PMID:15542774 |
Tp53 | Rat | mifepristone | decreases expression | ISO | RGD:11440 | 6480464 | Mifepristone results in decreased expression of TRP53 mRNA | CTD | PMID:12605714 |
Tp53 | Rat | minocycline | decreases expression | EXP | | 6480464 | Minocycline results in decreased expression of TP53 protein | CTD | PMID:15172883 |
Tp53 | Rat | mitomycin C | increases expression | ISO | RGD:70502 | 6480464 | Mitomycin results in increased expression of TP53; Mitomycin results in increased expression of TP53 mRNA; more ... | CTD | PMID:12082016|PMID:16186332|PMID:18647660|PMID:19834285|PMID:24675086|PMID:34624459 |
Tp53 | Rat | mitomycin C | affects activity | ISO | RGD:70502 | 6480464 | Mitomycin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | mitomycin C | affects localization | ISO | RGD:70502 | 6480464 | Mitomycin affects the localization of TP53 protein | CTD | PMID:35882637 |
Tp53 | Rat | mitomycin C | increases stability | ISO | RGD:70502 | 6480464 | Mitomycin results in increased stability of TP53 protein | CTD | PMID:20536192 |
Tp53 | Rat | mitomycin C | multiple interactions | ISO | RGD:70502 | 6480464 | [Mitomycin results in increased stability of TP53 protein] which results in increased expression of CDKN1A more ... | CTD | PMID:17530733|PMID:18647660|PMID:19834285|PMID:20536192|PMID:24675086|PMID:34624459 |
Tp53 | Rat | mitomycin C | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Mitomycin | CTD | PMID:15182437|PMID:20000476 |
Tp53 | Rat | Mitotane | multiple interactions | ISO | RGD:70502 | 6480464 | [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of more ... | CTD | PMID:9815696 |
Tp53 | Rat | Mitotane | increases expression | EXP | | 6480464 | Mitotane analog results in increased expression of TP53 mRNA; Mitotane results in increased expression of more ... | CTD | PMID:23485034 |
Tp53 | Rat | Mitotane | affects expression | EXP | | 6480464 | Mitotane analog affects the expression of TP53 protein | CTD | PMID:23485034 |
Tp53 | Rat | mitoxantrone | affects activity | ISO | RGD:70502 | 6480464 | Mitoxantrone affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | MK-2206 | multiple interactions | ISO | RGD:11440 | 6480464 | [mirdametinib co-treated with MK 2206] results in increased expression of and results in increased phosphorylation more ... | CTD | PMID:28691888 |
Tp53 | Rat | molinate | affects activity | ISO | RGD:70502 | 6480464 | molinate metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | molybdenum atom | multiple interactions | ISO | RGD:70502 | 6480464 | Molybdenum analog results in increased expression of and results in increased phosphorylation of TP53 protein | CTD | PMID:26391003 |
Tp53 | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:11440 | 6480464 | pifithrin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TP53 protein]; Selenomethionine inhibits the more ... | CTD | PMID:20659492|PMID:33162236 |
Tp53 | Rat | mono(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of TP53 mRNA | CTD | PMID:34141174 |
Tp53 | Rat | mono(2-ethylhexyl) phthalate | increases expression | ISO | RGD:70502 | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of TP53 protein | CTD | PMID:28988496 |
Tp53 | Rat | mono(2-ethylhexyl) phthalate | increases activity | ISO | RGD:70502 | 6480464 | mono-(2-ethylhexyl)phthalate results in increased activity of TP53 protein | CTD | PMID:21515331 |
Tp53 | Rat | mono(2-ethylhexyl) phthalate | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in decreased susceptibility to mono-(2-ethylhexyl)phthalate | CTD | PMID:24706461 |
Tp53 | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:70502 | 6480464 | gingerol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TP53 protein]; mono-(2-ethylhexyl)phthalate results in more ... | CTD | PMID:21515331|PMID:24706461|PMID:28988496 |
Tp53 | Rat | mono(2-ethylhexyl) phthalate | increases expression | ISO | RGD:11440 | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of TP53 protein; mono-(2-ethylhexyl)phthalate results in increased expression of TRP53 more ... | CTD | PMID:20659492|PMID:33162236|PMID:36174712 |
Tp53 | Rat | monobenzone | affects activity | ISO | RGD:70502 | 6480464 | monobenzone affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | monobenzyl phthalate | increases methylation | ISO | RGD:70502 | 6480464 | mono-benzyl phthalate results in increased methylation of TP53 promoter | CTD | PMID:35487445 |
Tp53 | Rat | monobenzyl phthalate | decreases expression | ISO | RGD:70502 | 6480464 | mono-benzyl phthalate results in decreased expression of TP53 mRNA | CTD | PMID:35487445 |
Tp53 | Rat | Monobutylphthalate | affects expression | EXP | | 6480464 | monobutyl phthalate affects the expression of TP53 mRNA; monobutyl phthalate affects the expression of TRP53 more ... | CTD | PMID:20864626|PMID:34141174 |
Tp53 | Rat | Monobutylphthalate | decreases expression | ISO | RGD:70502 | 6480464 | monobutyl phthalate results in decreased expression of TP53 mRNA | CTD | PMID:35487445 |
Tp53 | Rat | Monobutylphthalate | increases methylation | ISO | RGD:70502 | 6480464 | monobutyl phthalate results in increased methylation of TP53 promoter | CTD | PMID:35487445 |
Tp53 | Rat | monocrotaline | multiple interactions | ISO | RGD:70502 | 6480464 | [CYP3A4 protein results in increased metabolism of Monocrotaline] which results in increased expression of TP53 more ... | CTD | PMID:33884520 |
Tp53 | Rat | monocrotophos | increases expression | EXP | | 6480464 | Monocrotophos results in increased expression of TP53 mRNA; Monocrotophos results in increased expression of TP53 more ... | CTD | PMID:20957986|PMID:21445290 |
Tp53 | Rat | monomethyl succinate | multiple interactions | ISO | RGD:70502 | 6480464 | monomethyl succinate inhibits the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein] | CTD | PMID:21548882 |
Tp53 | Rat | monosodium L-glutamate | multiple interactions | ISO | RGD:11440 | 6480464 | [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of TRP53 mRNA; more ... | CTD | PMID:23783067 |
Tp53 | Rat | montelukast | multiple interactions | EXP | | 6480464 | montelukast inhibits the reaction [Rotenone results in increased expression of TP53 mRNA] | CTD | PMID:30222980 |
Tp53 | Rat | morin | increases expression | ISO | RGD:70502 | 6480464 | morin results in increased expression of TP53 mRNA | CTD | PMID:28689916 |
Tp53 | Rat | morin | multiple interactions | EXP | | 6480464 | morin inhibits the reaction [Ifosfamide results in increased expression of TP53 protein] | CTD | PMID:31722249 |
Tp53 | Rat | Morindone | increases expression | ISO | RGD:70502 | 6480464 | morindone results in increased expression of TP53 protein mutant form | CTD | PMID:38423379 |
Tp53 | Rat | Morindone | multiple interactions | ISO | RGD:70502 | 6480464 | [TP53 protein mutant form affects the susceptibility to morindone] which affects the expression of BAX more ... | CTD | PMID:38423379 |
Tp53 | Rat | Morindone | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein mutant form affects the susceptibility to morindone | CTD | PMID:38423379 |
Tp53 | Rat | Morindone | decreases expression | ISO | RGD:70502 | 6480464 | morindone results in decreased expression of TP53 mRNA mutant form | CTD | PMID:38423379 |
Tp53 | Rat | morphine | multiple interactions | ISO | RGD:70502 | 6480464 | [Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which more ... | CTD | PMID:12702572|PMID:12927789|PMID:19397953 |
Tp53 | Rat | morphine | increases expression | ISO | RGD:70502 | 6480464 | Morphine results in increased expression of TP53 mRNA | CTD | PMID:19397953 |
Tp53 | Rat | motexafin gadolinium | multiple interactions | ISO | RGD:70502 | 6480464 | [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of more ... | CTD | PMID:20530418 |
Tp53 | Rat | mozavaptan | affects activity | ISO | RGD:70502 | 6480464 | mozavaptan affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | mycophenolic acid | affects activity | ISO | RGD:70502 | 6480464 | Mycophenolic Acid affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | myo-inositol hexakisphosphate | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytic Acid inhibits the reaction [Glucose results in increased expression of more ... | CTD | PMID:16357363|PMID:38000455 |
Tp53 | Rat | myo-inositol hexakisphosphate | multiple interactions | EXP | | 6480464 | Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 protein] | CTD | PMID:16357363 |
Tp53 | Rat | myricetin | multiple interactions | ISO | RGD:70502 | 6480464 | myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of TP53 mRNA] | CTD | PMID:32342131 |
Tp53 | Rat | myricetin | increases expression | ISO | RGD:70502 | 6480464 | myricetin analog results in increased expression of TP53 mRNA; myricetin analog results in increased expression more ... | CTD | PMID:32220605 |
Tp53 | Rat | myricitrin | multiple interactions | ISO | RGD:70502 | 6480464 | myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] | CTD | PMID:23639522 |
Tp53 | Rat | myrtenal | multiple interactions | EXP | | 6480464 | myrtenal inhibits the reaction [[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA]; more ... | CTD | PMID:22436021 |
Tp53 | Rat | Myrtucommulone A | increases expression | ISO | RGD:11440 | 6480464 | myrtucommulone A results in increased expression of TRP53 mRNA | CTD | PMID:26032814 |
Tp53 | Rat | N(gamma)-nitro-L-arginine methyl ester | increases expression | EXP | | 6480464 | NG-Nitroarginine Methyl Ester results in increased expression of TP53 protein | CTD | PMID:32172062|PMID:32428650|PMID:32810514 |
Tp53 | Rat | N(gamma)-nitro-L-arginine methyl ester | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TP53 protein; [NG-Nitroarginine more ... | CTD | PMID:32172062|PMID:32428650|PMID:32810514 |
Tp53 | Rat | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | increases expression | ISO | RGD:70502 | 6480464 | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP53 protein | CTD | PMID:12888634 |
Tp53 | Rat | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | affects localization | ISO | RGD:70502 | 6480464 | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the localization of TP53 protein | CTD | PMID:18778698 |
Tp53 | Rat | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | multiple interactions | ISO | RGD:70502 | 6480464 | [Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased more ... | CTD | PMID:18778698|PMID:18951928 |
Tp53 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TP53 protein | CTD | PMID:12587291 |
Tp53 | Rat | N,N-dimethylformamide | multiple interactions | ISO | RGD:70502 | 6480464 | CAT protein inhibits the reaction [Dimethylformamide results in increased expression of TP53 protein]; Thiocarbamates analog more ... | CTD | PMID:29984871 |
Tp53 | Rat | N,N-dimethylformamide | increases expression | ISO | RGD:70502 | 6480464 | Dimethylformamide results in increased expression of TP53 protein modified form | CTD | PMID:29984871 |
Tp53 | Rat | N-acetoxy-2-acetamidofluorene | multiple interactions | EXP | | 6480464 | [Acetoxyacetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TP53 protein | CTD | PMID:10741303 |
Tp53 | Rat | N-acetyl-L-cysteine | multiple interactions | ISO | RGD:70502 | 6480464 | [Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased more ... | CTD | PMID:10951577|PMID:14871840|PMID:15059885|PMID:15489221|PMID:15496615|PMID:15904916|PMID:17555331|PMID:18034189|PMID:18951928|PMID:19202565|PMID:19728331|PMID:20530418|PMID:22183962|PMID:22260869|PMID:22927544|PMID:23274516|PMID:23711929|PMID:24792323|PMID:24967384|PMID:25305377|PMID:25939952|PMID:26451628|PMID:26884717|PMID:26942697|PMID:27634759|PMID:29944906|PMID:29945211|PMID:29962303|PMID:30265530|PMID:30408460|PMID:30555576|PMID:31433961|PMID:31715134|PMID:32017938|PMID:32540572|PMID:32905825|PMID:35065218|PMID:35123993|PMID:37487865|PMID:38311193|PMID:38431053|PMID:9535218 |
Tp53 | Rat | N-acetyl-L-cysteine | increases expression | ISO | RGD:70502 | 6480464 | Acetylcysteine results in increased expression of TP53 protein | CTD | PMID:31433961|PMID:35123993 |
Tp53 | Rat | N-acetyl-L-cysteine | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of TP53 protein]; Acetylcysteine inhibits the more ... | CTD | PMID:18563748|PMID:23907460|PMID:25845326|PMID:27658547|PMID:28181396|PMID:31173782|PMID:32402895|PMID:32924446|PMID:33031904|PMID:36493885 |
Tp53 | Rat | N-acetyl-L-cysteine | decreases expression | EXP | | 6480464 | Acetylcysteine results in decreased expression of TP53 protein | CTD | PMID:23183129 |
Tp53 | Rat | N-acetyl-L-cysteine | multiple interactions | ISO | RGD:11440 | 6480464 | Acetylcysteine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TRP53 protein]; Acetylcysteine inhibits the more ... | CTD | PMID:11864783|PMID:18996350|PMID:20955365|PMID:21462292|PMID:21549813|PMID:21565247|PMID:30555576|PMID:33961949 |
Tp53 | Rat | N-acetyl-L-cysteine | increases phosphorylation | EXP | | 6480464 | Acetylcysteine results in increased phosphorylation of TP53 protein | CTD | PMID:23907460 |
Tp53 | Rat | N-acetyl-L-cysteine | decreases activity | ISO | RGD:70502 | 6480464 | Acetylcysteine results in decreased activity of TP53 protein | CTD | PMID:15059885 |
Tp53 | Rat | N-acetylsphingosine | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the more ... | CTD | PMID:9535218 |
Tp53 | Rat | N-acetylsphingosine | increases expression | ISO | RGD:70502 | 6480464 | N-acetylsphingosine results in increased expression of TP53 mRNA; N-acetylsphingosine results in increased expression of TP53 more ... | CTD | PMID:9535218 |
Tp53 | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | multiple interactions | ISO | RGD:70502 | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] more ... | CTD | PMID:18951928|PMID:19699254|PMID:20530418|PMID:21454520|PMID:27129209|PMID:27993609 |
Tp53 | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | increases expression | EXP | | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 protein modified form | CTD | PMID:26612707 |
Tp53 | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | increases ubiquitination | EXP | | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of TP53 protein | CTD | PMID:18463101 |
Tp53 | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | multiple interactions | EXP | | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein more ... | CTD | PMID:16330492|PMID:18463101|PMID:26612707 |
Tp53 | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | increases expression | ISO | RGD:70502 | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression more ... | CTD | PMID:10837373|PMID:31806706|PMID:35821281 |
Tp53 | Rat | N-butyl-N-(4-hydroxybutyl)nitrosamine | affects activity | ISO | RGD:11440 | 6480464 | TRP53 affects the activity of Butylhydroxybutylnitrosamine | CTD | PMID:10395176 |
Tp53 | Rat | N-ethyl-N-nitrosourea | increases mutagenesis | EXP | | 6480464 | Ethylnitrosourea results in increased mutagenesis of TP53 gene | CTD | PMID:16495775 |
Tp53 | Rat | N-ethyl-N-nitrosourea | decreases expression | ISO | RGD:11440 | 6480464 | Ethylnitrosourea results in decreased expression of TRP53 protein | CTD | PMID:28549617 |
Tp53 | Rat | N-ethyl-N-nitrosourea | increases mutagenesis | ISO | RGD:70502 | 6480464 | Ethylnitrosourea results in increased mutagenesis of TP53 gene | CTD | PMID:14715658 |
Tp53 | Rat | N-ethyl-N-nitrosourea | multiple interactions | ISO | RGD:70502 | 6480464 | [Ethylnitrosourea results in increased mutagenesis of TP53 gene] which results in decreased activity of TP53 more ... | CTD | PMID:14715658 |
Tp53 | Rat | N-ethyl-N-nitrosourea | increases expression | ISO | RGD:11440 | 6480464 | Ethylnitrosourea results in increased expression of TRP53 protein | CTD | PMID:9667752 |
Tp53 | Rat | N-ethyl-N-nitrosourea | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in increased susceptibility to Ethylnitrosourea | CTD | PMID:16436596 |
Tp53 | Rat | N-ethyl-N-nitrosourea | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 affects the susceptibility to Ethylnitrosourea | CTD | PMID:11053539 |
Tp53 | Rat | N-ethyl-N-nitrosourea | increases mutagenesis | ISO | RGD:11440 | 6480464 | Ethylnitrosourea results in increased mutagenesis of TRP53 exon; Ethylnitrosourea results in increased mutagenesis of TRP53 more ... | CTD | PMID:15790496|PMID:16357521|PMID:16724327 |
Tp53 | Rat | N-hydroxy-2-acetamidofluorene | increases expression | EXP | | 6480464 | Hydroxyacetylaminofluorene results in increased expression of TP53 protein | CTD | PMID:9163691 |
Tp53 | Rat | N-hydroxy-4-aminobiphenyl | multiple interactions | ISO | RGD:70502 | 6480464 | [N-hydroxy-4-aminobiphenyl co-treated with Copper] results in increased mutagenesis of TP53 gene | CTD | PMID:11275476 |
Tp53 | Rat | N-hydroxy-PhIP | increases mutagenesis | ISO | RGD:70502 | 6480464 | 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of TP53 protein | CTD | PMID:33189884 |
Tp53 | Rat | N-methyl-4-phenylpyridinium | increases acetylation | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased acetylation of TP53 protein | CTD | PMID:17583434 |
Tp53 | Rat | N-methyl-4-phenylpyridinium | multiple interactions | EXP | | 6480464 | ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TP53 protein]; pifithrin inhibits the more ... | CTD | PMID:33737050 |
Tp53 | Rat | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of TP53 protein | CTD | PMID:26677001|PMID:33737050 |
Tp53 | Rat | N-methyl-4-phenylpyridinium | decreases expression | ISO | RGD:70502 | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of TP53 mRNA | CTD | PMID:24810058 |
Tp53 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | RGD:70502 | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of TP53 mRNA; 1-Methyl-4-phenylpyridinium results in increased expression of TP53 more ... | CTD | PMID:26357513|PMID:28481321 |
Tp53 | Rat | N-methyl-4-phenylpyridinium | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to 1-Methyl-4-phenylpyridinium | CTD | PMID:23500530 |
Tp53 | Rat | N-methyl-4-phenylpyridinium | multiple interactions | ISO | RGD:70502 | 6480464 | [EEF1A2 protein affects the susceptibility to 1-Methyl-4-phenylpyridinium] which affects the expression of TP53 mRNA; atractylenolide more ... | CTD | PMID:12710931|PMID:26357513|PMID:28481321|PMID:37051183 |
Tp53 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | increases expression | ISO | RGD:70502 | 6480464 | Methylnitronitrosoguanidine results in increased expression of TP53 mRNA; Methylnitronitrosoguanidine results in increased expression of TP53 more ... | CTD | PMID:12634122|PMID:26921499 |
Tp53 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | multiple interactions | ISO | RGD:70502 | 6480464 | ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]; CHEK2 protein more ... | CTD | PMID:26025680|PMID:26921499 |
Tp53 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | increases expression | ISO | RGD:11440 | 6480464 | Methylnitronitrosoguanidine results in increased expression of TRP53 protein | CTD | PMID:11516527|PMID:12135628|PMID:9667752 |
Tp53 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | multiple interactions | ISO | RGD:11440 | 6480464 | [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TRP53 mRNA; Cadmium Chloride inhibits more ... | CTD | PMID:11516527|PMID:12135628 |
Tp53 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | decreases expression | EXP | | 6480464 | Methylnitronitrosoguanidine results in decreased expression of TP53 protein | CTD | PMID:19851710 |
Tp53 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | multiple interactions | EXP | | 6480464 | Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TP53 protein]; resveratrol inhibits the more ... | CTD | PMID:17147953|PMID:19851710 |
Tp53 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | increases acetylation | EXP | | 6480464 | Methylnitronitrosoguanidine results in increased acetylation of TP53 protein | CTD | PMID:17147953 |
Tp53 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Methylnitronitrosoguanidine | CTD | PMID:15589979 |
Tp53 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein mutant form results in decreased susceptibility to Methylnitronitrosoguanidine | CTD | PMID:15589979 |
Tp53 | Rat | N-methyl-N-nitrosourea | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with Methylnitrosourea co-treated with Progesterone] results in decreased expression of TP53 mRNA; [Methylnitrosourea more ... | CTD | PMID:18593901|PMID:20732338 |
Tp53 | Rat | N-methyl-N-nitrosourea | multiple interactions | ISO | RGD:70502 | 6480464 | Methylnitrosourea results in increased expression of and results in increased phosphorylation of TP53 protein; TP53 more ... | CTD | PMID:27233451|PMID:29110037 |
Tp53 | Rat | N-methyl-N-nitrosourea | increases stability | ISO | RGD:70502 | 6480464 | Methylnitrosourea results in increased stability of TP53 protein | CTD | PMID:27233451 |
Tp53 | Rat | N-methyl-N-nitrosourea | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Methylnitrosourea | CTD | PMID:12185594 |
Tp53 | Rat | N-methyl-N-nitrosourea | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in increased susceptibility to Methylnitrosourea | CTD | PMID:11536039 |
Tp53 | Rat | N-methyl-N-nitrosourea | increases phosphorylation | ISO | RGD:11440 | 6480464 | Methylnitrosourea results in increased phosphorylation of TRP53 protein | CTD | PMID:18593901|PMID:21285353 |
Tp53 | Rat | N-methyl-N-nitrosourea | multiple interactions | ISO | RGD:11440 | 6480464 | Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein]; MAPK8 protein more ... | CTD | PMID:11536039|PMID:11850828|PMID:18593901|PMID:21285353 |
Tp53 | Rat | N-methyl-N-nitrosourea | increases phosphorylation | EXP | | 6480464 | Methylnitrosourea results in increased phosphorylation of TP53 protein | CTD | PMID:18593901 |
Tp53 | Rat | N-methyl-N-nitrosourea | increases expression | EXP | | 6480464 | Methylnitrosourea results in increased expression of TP53 mRNA | CTD | PMID:17412507|PMID:28688903 |
Tp53 | Rat | N-Nitrosodi-n-butylamine | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in increased susceptibility to dibutylnitrosamine | CTD | PMID:12706858 |
Tp53 | Rat | N-nitrosodiethylamine | decreases expression | EXP | | 6480464 | Diethylnitrosamine results in decreased expression of TP53 mRNA; Diethylnitrosamine results in decreased expression of TP53 more ... | CTD | PMID:21167192|PMID:21554863|PMID:24954034|PMID:30423403 |
Tp53 | Rat | N-nitrosodiethylamine | multiple interactions | ISO | RGD:70502 | 6480464 | [CYP2A6 protein results in increased metabolism of Diethylnitrosamine] which affects the localization of TP53 protein | CTD | PMID:35882637 |
Tp53 | Rat | N-nitrosodiethylamine | increases expression | ISO | RGD:70502 | 6480464 | Diethylnitrosamine results in increased expression of TP53 protein | CTD | PMID:21776270 |
Tp53 | Rat | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of TP53 mRNA; Diethylnitrosamine results in increased expression of TP53 more ... | CTD | PMID:11751435|PMID:14555611|PMID:18367157|PMID:19254457|PMID:19874807|PMID:20360939|PMID:9163691 |
Tp53 | Rat | N-nitrosodiethylamine | increases phosphorylation | EXP | | 6480464 | Diethylnitrosamine results in increased phosphorylation of TP53 protein | CTD | PMID:11751435 |
Tp53 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [5,7-dimethoxyflavone co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA; [5,7-dimethoxyflavone co-treated with Diethylnitrosamine] more ... | CTD | PMID:10741303|PMID:11003613|PMID:11751435|PMID:11915028|PMID:14633663|PMID:15459018|PMID:17602206|PMID:18367157|PMID:18544905|PMID:19874807|PMID:20360939|PMID:21167192|PMID:21554863|PMID:21907755|PMID:22436021|PMID:23665045|PMID:30423403 |
Tp53 | Rat | N-nitrosodiethylamine | increases expression | ISO | RGD:11440 | 6480464 | Diethylnitrosamine results in increased expression of TRP53 protein | CTD | PMID:19919837 |
Tp53 | Rat | N-nitrosodiethylamine | decreases expression | ISO | RGD:11440 | 6480464 | Diethylnitrosamine results in decreased expression of TRP53 mRNA; Diethylnitrosamine results in decreased expression of TRP53 more ... | CTD | PMID:18506893|PMID:19996281|PMID:34726822 |
Tp53 | Rat | N-nitrosodiethylamine | multiple interactions | ISO | RGD:11440 | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of TRP53 more ... | CTD | PMID:17917374|PMID:18506893|PMID:19919837|PMID:19996281|PMID:21167249|PMID:31067004|PMID:34726822 |
Tp53 | Rat | N-nitrosodiethylamine | | ISO | RGD:11440 | 127285675 | N-nitrosodiethylamine increases expression of Trp53 mRNA in liver | RGD | |
Tp53 | Rat | N-nitrosomorpholine | increases expression | EXP | | 6480464 | N-nitrosomorpholine results in increased expression of TP53 protein | CTD | PMID:10326863|PMID:14587038|PMID:7728945 |
Tp53 | Rat | N-tosyl-L-phenylalanyl chloromethyl ketone | multiple interactions | ISO | RGD:70502 | 6480464 | Tosylphenylalanyl Chloromethyl Ketone results in decreased phosphorylation of and results in increased activity of TP53 more ... | CTD | PMID:12821135 |
Tp53 | Rat | N-tosyl-L-phenylalanyl chloromethyl ketone | decreases expression | ISO | RGD:11440 | 6480464 | Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of TRP53 protein | CTD | PMID:11536013 |
Tp53 | Rat | N-tosyl-L-phenylalanyl chloromethyl ketone | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Tosylphenylalanyl Chloromethyl Ketone | CTD | PMID:12821135 |
Tp53 | Rat | NAD zwitterion | multiple interactions | ISO | RGD:70502 | 6480464 | [2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene; more ... | CTD | PMID:10334203|PMID:34216621 |
Tp53 | Rat | NAD zwitterion | multiple interactions | ISO | RGD:11440 | 6480464 | NAD promotes the reaction [Acetaminophen results in decreased expression of TRP53 protein] | CTD | PMID:11461765 |
Tp53 | Rat | NAD zwitterion | decreases expression | ISO | RGD:70502 | 6480464 | NAD results in decreased expression of TP53 protein | CTD | PMID:12390773 |
Tp53 | Rat | NAD(+) | multiple interactions | ISO | RGD:70502 | 6480464 | [2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene; more ... | CTD | PMID:10334203|PMID:34216621 |
Tp53 | Rat | NAD(+) | multiple interactions | ISO | RGD:11440 | 6480464 | NAD promotes the reaction [Acetaminophen results in decreased expression of TRP53 protein] | CTD | PMID:11461765 |
Tp53 | Rat | NAD(+) | decreases expression | ISO | RGD:70502 | 6480464 | NAD results in decreased expression of TP53 protein | CTD | PMID:12390773 |
Tp53 | Rat | NADP zwitterion | multiple interactions | ISO | RGD:70502 | 6480464 | NADP promotes the reaction [sodium bichromate results in increased expression of TP53 protein] | CTD | PMID:10942736 |
Tp53 | Rat | NADP(+) | multiple interactions | ISO | RGD:70502 | 6480464 | NADP promotes the reaction [sodium bichromate results in increased expression of TP53 protein] | CTD | PMID:10942736 |
Tp53 | Rat | naloxone | multiple interactions | ISO | RGD:70502 | 6480464 | Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 more ... | CTD | PMID:12927789|PMID:19397953 |
Tp53 | Rat | naloxone | decreases expression | EXP | | 6480464 | Naloxone results in decreased expression of TP53 mRNA | CTD | PMID:17522070 |
Tp53 | Rat | naphthalene | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to naphthalene | CTD | PMID:10802220 |
Tp53 | Rat | naphthalene | multiple interactions | ISO | RGD:70502 | 6480464 | [naphthalene binds to pyrrolo(2,1-c)(1,4)benzodiazepine] which results in increased expression of TP53 protein | CTD | PMID:21732540 |
Tp53 | Rat | naphthalenes | increases expression | ISO | RGD:70502 | 6480464 | Naphthalenes results in increased expression of TP53 protein | CTD | PMID:17224139 |
Tp53 | Rat | naringin | increases expression | ISO | RGD:70502 | 6480464 | naringin results in increased expression of TP53 mRNA | CTD | PMID:22847135 |
Tp53 | Rat | naringin | decreases expression | EXP | | 6480464 | naringin results in decreased expression of TP53 protein | CTD | PMID:32428650 |
Tp53 | Rat | naringin | multiple interactions | ISO | RGD:11440 | 6480464 | naringin inhibits the reaction [Doxorubicin results in increased expression of TRP53 protein]; SIRT1 protein affects more ... | CTD | PMID:36811345 |
Tp53 | Rat | naringin | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with naringin] results in decreased expression of TP53 protein; [NG-Nitroarginine Methyl Ester more ... | CTD | PMID:26120027|PMID:26612654|PMID:32172062|PMID:32428650|PMID:32810514|PMID:36598108 |
Tp53 | Rat | Neferine | multiple interactions | EXP | | 6480464 | neferine inhibits the reaction [Diethylnitrosamine results in decreased expression of TP53 mRNA] | CTD | PMID:30423403 |
Tp53 | Rat | neoastilbin | multiple interactions | ISO | RGD:70502 | 6480464 | astilbin inhibits the reaction [Cisplatin results in increased expression of TP53 protein] | CTD | PMID:29471006 |
Tp53 | Rat | neocuproine | multiple interactions | ISO | RGD:70502 | 6480464 | neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 more ... | CTD | PMID:29803612 |
Tp53 | Rat | nickel atom | multiple interactions | ISO | RGD:70502 | 6480464 | [cobalt ferrite binds to Nickel] which results in increased expression of TP53 protein; [Quercetin analog more ... | CTD | PMID:20577783|PMID:24068677|PMID:36073959 |
Tp53 | Rat | nickel atom | increases expression | ISO | RGD:70502 | 6480464 | Nickel analog results in increased expression of TP53 protein | CTD | PMID:23776134 |
Tp53 | Rat | nickel atom | decreases expression | ISO | RGD:70502 | 6480464 | Nickel results in decreased expression of TP53 mRNA | CTD | PMID:23195993 |
Tp53 | Rat | nickel dichloride | increases expression | ISO | RGD:11440 | 6480464 | nickel chloride results in increased expression of TRP53 mRNA; nickel chloride results in increased expression more ... | CTD | PMID:12426141|PMID:12839937|PMID:36421005 |
Tp53 | Rat | nickel dichloride | multiple interactions | ISO | RGD:11440 | 6480464 | Melatonin inhibits the reaction [nickel chloride results in increased expression of TRP53 mRNA]; Melatonin inhibits more ... | CTD | PMID:36421005 |
Tp53 | Rat | nickel dichloride | decreases activity | ISO | RGD:70502 | 6480464 | nickel chloride results in decreased activity of TP53 protein | CTD | PMID:25446071 |
Tp53 | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of TP53 mRNA | CTD | PMID:22546817 |
Tp53 | Rat | nickel dichloride | multiple interactions | ISO | RGD:70502 | 6480464 | [nickel chloride results in decreased activity of TP53 protein] inhibits the reaction [TP53 protein binds more ... | CTD | PMID:23566959|PMID:25446071 |
Tp53 | Rat | nickel dichloride | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 mutant form results in decreased susceptibility to nickel chloride | CTD | PMID:23566959 |
Tp53 | Rat | nickel dichloride | increases expression | ISO | RGD:70502 | 6480464 | nickel chloride results in increased expression of TP53 protein; nickel chloride results in increased expression more ... | CTD | PMID:23566959|PMID:28552779|PMID:29110037 |
Tp53 | Rat | nickel dichloride | increases phosphorylation | ISO | RGD:70502 | 6480464 | nickel chloride results in increased phosphorylation of TP53 protein | CTD | PMID:21466819 |
Tp53 | Rat | nickel ferrite | increases expression | ISO | RGD:70502 | 6480464 | nickel ferrite analog results in increased expression of TP53 mRNA; nickel ferrite results in increased more ... | CTD | PMID:21382431|PMID:25966046 |
Tp53 | Rat | nickel subsulfide | decreases expression | EXP | | 6480464 | nickel subsulfide results in decreased expression of TP53 mRNA | CTD | PMID:24952340 |
Tp53 | Rat | nickel sulfate | multiple interactions | ISO | RGD:70502 | 6480464 | nickel sulfate inhibits the reaction [Potassium Dichromate results in increased phosphorylation of TP53 protein] | CTD | PMID:20493934 |
Tp53 | Rat | nickel sulfate | increases expression | ISO | RGD:70502 | 6480464 | nickel sulfate results in increased expression of TP53 protein | CTD | PMID:21776270|PMID:23568779 |
Tp53 | Rat | niclosamide | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in increased susceptibility to Niclosamide; TP53 protein mutant form results more ... | CTD | PMID:30258081 |
Tp53 | Rat | niclosamide | multiple interactions | ISO | RGD:11440 | 6480464 | [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance more ... | CTD | PMID:30258081 |
Tp53 | Rat | niclosamide | increases expression | ISO | RGD:70502 | 6480464 | Niclosamide results in increased expression of TP53 mRNA; Niclosamide results in increased expression of TP53 more ... | CTD | PMID:22576131|PMID:29031202|PMID:30258081|PMID:36318118 |
Tp53 | Rat | niclosamide | increases expression | ISO | RGD:11440 | 6480464 | Niclosamide results in increased expression of TRP53 protein | CTD | PMID:30258081 |
Tp53 | Rat | niclosamide | multiple interactions | ISO | RGD:70502 | 6480464 | [Niclosamide binds to Polyethyleneimine] which results in increased expression of TP53 mRNA; TP53 gene mutant more ... | CTD | PMID:25988281|PMID:30258081 |
Tp53 | Rat | niclosamide | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in decreased susceptibility to Niclosamide | CTD | PMID:30258081 |
Tp53 | Rat | nicorandil | multiple interactions | EXP | | 6480464 | Nicorandil inhibits the reaction [Methotrexate results in increased expression of TP53 protein] | CTD | PMID:32666843 |
Tp53 | Rat | nicotinamide | multiple interactions | ISO | RGD:70502 | 6480464 | [Berberine co-treated with Niacinamide] results in increased expression of and results in increased acetylation of more ... | CTD | PMID:12782109|PMID:18482975|PMID:18681908|PMID:26712469 |
Tp53 | Rat | nicotinamide | multiple interactions | ISO | RGD:11440 | 6480464 | [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in more ... | CTD | PMID:25478867 |
Tp53 | Rat | nicotinamide | decreases expression | ISO | RGD:70502 | 6480464 | Niacinamide results in decreased expression of TP53 protein | CTD | PMID:12782109 |
Tp53 | Rat | nicotine | multiple interactions | ISO | RGD:70502 | 6480464 | 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [Nicotine results in decreased expression of TP53 protein]; [[Nicotine results in more ... | CTD | PMID:16601104|PMID:18805435|PMID:19139119|PMID:20727180|PMID:23907605|PMID:30272249 |
Tp53 | Rat | nicotine | increases expression | ISO | RGD:11440 | 6480464 | Nicotine results in increased expression of TRP53 mRNA; Nicotine results in increased expression of TRP53 more ... | CTD | PMID:30896085|PMID:31507073 |
Tp53 | Rat | nicotine | increases expression | ISO | RGD:70502 | 6480464 | Nicotine results in increased expression of TP53 protein | CTD | PMID:20727180 |
Tp53 | Rat | nicotine | decreases expression | ISO | RGD:70502 | 6480464 | Nicotine results in decreased expression of TP53 mRNA; Nicotine results in decreased expression of TP53 more ... | CTD | PMID:16011614|PMID:18247414|PMID:18805435|PMID:19139119|PMID:30272249 |
Tp53 | Rat | nicotine | decreases expression | ISO | RGD:11440 | 6480464 | Nicotine results in decreased expression of TRP53 protein | CTD | PMID:18835254 |
Tp53 | Rat | nicotine | multiple interactions | ISO | RGD:11440 | 6480464 | [Nicotine co-treated with Polylactic Acid-Polyglycolic Acid Copolymer] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression more ... | CTD | PMID:23933227|PMID:30896085 |
Tp53 | Rat | nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of TP53 mRNA | CTD | PMID:20339300|PMID:20426880 |
Tp53 | Rat | nicotine | affects response to substance | EXP | | 6480464 | TP53 protein affects the susceptibility to Nicotine | CTD | PMID:15983034 |
Tp53 | Rat | nicotine | affects expression | EXP | | 6480464 | Nicotine affects the expression of TP53 mRNA | CTD | PMID:10837795 |
Tp53 | Rat | nicotinic acid | multiple interactions | EXP | | 6480464 | Niacin deficiency inhibits the reaction [Etoposide results in increased expression of TP53 protein] | CTD | PMID:17516866 |
Tp53 | Rat | nicotinic acid | decreases expression | EXP | | 6480464 | Niacin deficiency results in decreased expression of TP53 mRNA | CTD | PMID:17516866 |
Tp53 | Rat | nicotinic acid | affects expression | EXP | | 6480464 | Niacin deficiency affects the expression of TP53 protein | CTD | PMID:17516866 |
Tp53 | Rat | nifedipine | increases activity | ISO | RGD:70502 | 6480464 | Nifedipine results in increased activity of TP53 protein | CTD | PMID:12082016 |
Tp53 | Rat | nifuroxazide | affects activity | ISO | RGD:70502 | 6480464 | nifuroxazide affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | nilotinib | increases secretion | ISO | RGD:70502 | 6480464 | nilotinib results in increased secretion of TP53 protein | CTD | PMID:29370077 |
Tp53 | Rat | nimustine | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 affects the reaction [Nimustine results in increased expression of DDB2 mRNA]; TP53 affects the more ... | CTD | PMID:18089819 |
Tp53 | Rat | nimustine | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Nimustine | CTD | PMID:15182437 |
Tp53 | Rat | ninhydrin | affects activity | ISO | RGD:70502 | 6480464 | Ninhydrin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | nitenpyram | increases expression | ISO | RGD:70502 | 6480464 | nitenpyram results in increased expression of TP53 mRNA | CTD | PMID:35568224 |
Tp53 | Rat | nitrates | multiple interactions | ISO | RGD:11440 | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of TRP53 more ... | CTD | PMID:35964746 |
Tp53 | Rat | nitric oxide | increases phosphorylation | ISO | RGD:70502 | 6480464 | Nitric Oxide results in increased phosphorylation of TP53 protein | CTD | PMID:15177039|PMID:16024610 |
Tp53 | Rat | nitric oxide | increases glutathionylation | ISO | RGD:70502 | 6480464 | Nitric Oxide results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | nitric oxide | increases expression | ISO | RGD:70502 | 6480464 | Nitric Oxide results in increased expression of TP53 protein | CTD | PMID:15979383 |
Tp53 | Rat | nitric oxide | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nitric Oxide results in increased phosphorylation of TP53 protein]; [Nitric Oxide more ... | CTD | PMID:10608825|PMID:16024610 |
Tp53 | Rat | nitric oxide | multiple interactions | ISO | RGD:11440 | 6480464 | [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] which results in increased expression of TRP53 more ... | CTD | PMID:7673702 |
Tp53 | Rat | nitric oxide | decreases expression | ISO | RGD:11440 | 6480464 | Nitric Oxide results in decreased expression of TRP53 protein | CTD | PMID:14634119 |
Tp53 | Rat | nitric oxide | multiple interactions | EXP | | 6480464 | [7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat results in more ... | CTD | PMID:20478973|PMID:8982730|PMID:9743513 |
Tp53 | Rat | nitric oxide | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Nitric Oxide | CTD | PMID:16024610 |
Tp53 | Rat | nitrofurazone | increases mutagenesis | ISO | RGD:70502 | 6480464 | Nitrofurazone results in increased mutagenesis of TP53 gene | CTD | PMID:15488632 |
Tp53 | Rat | nitrogen dioxide | increases expression | EXP | | 6480464 | Nitrogen Dioxide results in increased expression of TP53 mRNA; Nitrogen Dioxide results in increased expression more ... | CTD | PMID:22621880 |
Tp53 | Rat | nitrogen dioxide | multiple interactions | ISO | RGD:11440 | 6480464 | [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of more ... | CTD | PMID:27521637 |
Tp53 | Rat | nitrogen mustard | multiple interactions | ISO | RGD:70502 | 6480464 | caffeic acid phenethyl ester inhibits the reaction [Nitrogen Mustard Compounds results in increased phosphorylation of more ... | CTD | PMID:17204746 |
Tp53 | Rat | nitrogen mustard | increases phosphorylation | ISO | RGD:70502 | 6480464 | Nitrogen Mustard Compounds results in increased phosphorylation of TP53 protein | CTD | PMID:17204746 |
Tp53 | Rat | nitroprusside | multiple interactions | EXP | | 6480464 | cilostazol inhibits the reaction [Nitroprusside results in increased phosphorylation of TP53 protein] | CTD | PMID:18311796 |
Tp53 | Rat | nitroprusside | increases phosphorylation | EXP | | 6480464 | Nitroprusside results in increased phosphorylation of TP53 protein | CTD | PMID:18311796 |
Tp53 | Rat | nitroprusside | increases expression | ISO | RGD:70502 | 6480464 | Nitroprusside results in increased expression of TP53 protein | CTD | PMID:15979383 |
Tp53 | Rat | Nitrovin | affects activity | ISO | RGD:70502 | 6480464 | Nitrovin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | NMS-873 | increases expression | ISO | RGD:70502 | 6480464 | NMS-873 results in increased expression of TP53 protein | CTD | PMID:29693262 |
Tp53 | Rat | nocodazole | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of JUN protein]; TP53 protein more ... | CTD | PMID:12221076 |
Tp53 | Rat | nocodazole | increases expression | ISO | RGD:70502 | 6480464 | Nocodazole analog results in increased expression of TP53 protein; Nocodazole results in increased expression of more ... | CTD | PMID:21559451|PMID:28412508 |
Tp53 | Rat | Nonidet P-40 | decreases expression | ISO | RGD:70502 | 6480464 | Nonidet P-40 results in decreased expression of TP53 mRNA | CTD | PMID:26552463 |
Tp53 | Rat | norethisterone | multiple interactions | ISO | RGD:70502 | 6480464 | Norethindrone results in increased expression of and results in increased activity of TP53 protein | CTD | PMID:15905198 |
Tp53 | Rat | notoginsenoside R1 | multiple interactions | ISO | RGD:11440 | 6480464 | notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TRP53 mRNA]; notoginsenoside R1 more ... | CTD | PMID:23170834 |
Tp53 | Rat | NS-398 | multiple interactions | ISO | RGD:70502 | 6480464 | [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [Ceramides results in increased more ... | CTD | PMID:16928824|PMID:18446786|PMID:23495037|PMID:29242151 |
Tp53 | Rat | NS-398 | decreases expression | ISO | RGD:70502 | 6480464 | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of TP53 mRNA | CTD | PMID:29242151 |
Tp53 | Rat | NS-398 | multiple interactions | EXP | | 6480464 | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein] | CTD | PMID:17984113 |
Tp53 | Rat | Nutlin-3 | increases activity | ISO | RGD:70502 | 6480464 | nutlin 3 results in increased activity of TP53 protein | CTD | PMID:16014563 |
Tp53 | Rat | Nutlin-3 | increases stability | ISO | RGD:70502 | 6480464 | nutlin 3 results in increased stability of TP53 protein | CTD | PMID:21205074 |
Tp53 | Rat | Nutlin-3 | increases expression | ISO | RGD:70502 | 6480464 | nutlin 3 results in increased expression of TP53 mRNA; nutlin 3 results in increased expression more ... | CTD | PMID:16439685|PMID:18092340|PMID:19098008|PMID:21212465|PMID:21532991|PMID:21624110|PMID:22044530|PMID:22260869|PMID:24726431|PMID:35213076 |
Tp53 | Rat | Nutlin-3 | increases expression | ISO | RGD:11440 | 6480464 | nutlin 3 results in increased expression of TRP53 protein | CTD | PMID:16949053 |
Tp53 | Rat | Nutlin-3 | increases activity | ISO | RGD:11440 | 6480464 | nutlin 3 results in increased activity of TRP53 protein | CTD | PMID:16949053 |
Tp53 | Rat | Nutlin-3 | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 results in increased susceptibility to nutlin 3 | CTD | PMID:21624110 |
Tp53 | Rat | Nutlin-3 | multiple interactions | ISO | RGD:70502 | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of and results in increased secretion more ... | CTD | PMID:16014563|PMID:16439677|PMID:16439685|PMID:20530418|PMID:21109480|PMID:21205074|PMID:21509038|PMID:21624110|PMID:22044530|PMID:22260869|PMID:24726431|PMID:35213076|PMID:38460933 |
Tp53 | Rat | O-(chloroacetylcarbamoyl)fumagillol | increases expression | ISO | RGD:70502 | 6480464 | O-(chloroacetylcarbamoyl)fumagillol results in increased expression of TP53 protein | CTD | PMID:15276080 |
Tp53 | Rat | O-methyleugenol | increases expression | EXP | | 6480464 | methyleugenol results in increased expression of TP53 protein | CTD | PMID:23411599 |
Tp53 | Rat | O-methyleugenol | decreases expression | EXP | | 6480464 | methyleugenol results in decreased expression of TP53 mRNA | CTD | PMID:26011634 |
Tp53 | Rat | Obacunone | increases expression | ISO | RGD:70502 | 6480464 | obacunone results in increased expression of TP53 protein | CTD | PMID:21333732|PMID:25592883 |
Tp53 | Rat | ochratoxin A | decreases expression | EXP | | 6480464 | ochratoxin A results in decreased expression of TP53 | CTD | PMID:25218026 |
Tp53 | Rat | ochratoxin A | increases phosphorylation | ISO | RGD:70502 | 6480464 | ochratoxin A results in increased phosphorylation of TP53 protein | CTD | PMID:39117293 |
Tp53 | Rat | ochratoxin A | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form inhibits the reaction [ochratoxin A results in increased expression of CDKN1A more ... | CTD | PMID:25636497 |
Tp53 | Rat | ochratoxin A | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in increased susceptibility to ochratoxin A | CTD | PMID:25636497 |
Tp53 | Rat | ochratoxin A | increases expression | ISO | RGD:11440 | 6480464 | ochratoxin A results in increased expression of TRP53 protein | CTD | PMID:23261758|PMID:25636497 |
Tp53 | Rat | ochratoxin A | multiple interactions | ISO | RGD:70502 | 6480464 | MLH1 protein affects the reaction [ochratoxin A results in increased phosphorylation of TP53 protein]; ochratoxin more ... | CTD | PMID:24525463|PMID:32910239|PMID:39117293 |
Tp53 | Rat | ochratoxin A | decreases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein results in decreased susceptibility to ochratoxin A | CTD | PMID:23261758 |
Tp53 | Rat | ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of TP53 mRNA | CTD | PMID:19562491|PMID:23208426 |
Tp53 | Rat | ochratoxin A | increases phosphorylation | ISO | RGD:11440 | 6480464 | ochratoxin A results in increased phosphorylation of TRP53 protein | CTD | PMID:19445961 |
Tp53 | Rat | ochratoxin A | increases expression | ISO | RGD:70502 | 6480464 | ochratoxin A results in increased expression of TP53 mRNA; ochratoxin A results in increased expression more ... | CTD | PMID:19367635|PMID:28286205|PMID:31154016 |
Tp53 | Rat | Octicizer | increases expression | ISO | RGD:70502 | 6480464 | 2-ethylhexyldiphenylphosphate results in increased expression of TP53 mRNA | CTD | PMID:30981936 |
Tp53 | Rat | octreotide | decreases expression | ISO | RGD:70502 | 6480464 | Octreotide results in decreased expression of TP53 protein | CTD | PMID:21764706 |
Tp53 | Rat | okadaic acid | multiple interactions | ISO | RGD:70502 | 6480464 | Okadaic Acid affects the reaction [Estradiol promotes the reaction [Benzo(a)pyrene affects the localization of TP53 more ... | CTD | PMID:24954032 |
Tp53 | Rat | okadaic acid | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to Okadaic Acid | CTD | PMID:20477944 |
Tp53 | Rat | okadaic acid | decreases expression | ISO | RGD:70502 | 6480464 | Okadaic Acid results in decreased expression of TP53 mRNA; Okadaic Acid results in decreased expression more ... | CTD | PMID:18937299|PMID:31926150 |
Tp53 | Rat | okadaic acid | affects localization | ISO | RGD:70502 | 6480464 | Okadaic Acid affects the localization of TP53 protein | CTD | PMID:21512803 |
Tp53 | Rat | olanzapine | increases expression | ISO | RGD:70502 | 6480464 | olanzapine results in increased expression of TP53 mRNA | CTD | PMID:16160616 |
Tp53 | Rat | olaparib | multiple interactions | ISO | RGD:70502 | 6480464 | [Fluorouracil co-treated with olaparib] results in increased expression of TP53 protein; TP53 gene mutant form more ... | CTD | PMID:26544897 |
Tp53 | Rat | olaparib | increases phosphorylation | ISO | RGD:70502 | 6480464 | olaparib results in increased phosphorylation of TP53 protein | CTD | PMID:25531448 |
Tp53 | Rat | oleanolic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [Oleanolic Acid results in increased susceptibility to Doxorubicin] which affects the expression of TP53 mRNA | CTD | PMID:37345903 |
Tp53 | Rat | oleic acid | multiple interactions | ISO | RGD:70502 | 6480464 | 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased more ... | CTD | PMID:32369900 |
Tp53 | Rat | oleuropein | multiple interactions | EXP | | 6480464 | oleuropein inhibits the reaction [decamethrin results in increased expression of TP53 protein] | CTD | PMID:28595958 |
Tp53 | Rat | olomoucine | multiple interactions | ISO | RGD:70502 | 6480464 | olomoucine inhibits the reaction [TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of more ... | CTD | PMID:16628227 |
Tp53 | Rat | omacetaxine mepesuccinate | multiple interactions | ISO | RGD:70502 | 6480464 | [Arsenic Trioxide co-treated with Homoharringtonine] results in increased expression of TP53 protein; crenigacestat inhibits the more ... | CTD | PMID:31307525 |
Tp53 | Rat | omacetaxine mepesuccinate | increases expression | ISO | RGD:70502 | 6480464 | Homoharringtonine results in increased expression of TP53 protein | CTD | PMID:31307525 |
Tp53 | Rat | omethoate | decreases expression | ISO | RGD:70502 | 6480464 | dimethoxon results in decreased expression of TP53 mRNA | CTD | PMID:28718371 |
Tp53 | Rat | orlistat | multiple interactions | EXP | | 6480464 | Orlistat inhibits the reaction [Dietary Fats results in increased expression of TP53 mRNA] | CTD | PMID:32450208 |
Tp53 | Rat | oroxylin A | multiple interactions | ISO | RGD:70502 | 6480464 | diacetyldiphenylurea bisguanylhydrazone inhibits the reaction [5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in increased expression of TP53 protein modified form] | CTD | PMID:23470866 |
Tp53 | Rat | oroxylin A | increases expression | ISO | RGD:70502 | 6480464 | 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in increased expression of TP53 protein modified form | CTD | PMID:23470866 |
Tp53 | Rat | ortho-Aminoazotoluene | increases expression | ISO | RGD:11440 | 6480464 | o-Aminoazotoluene results in increased expression of TRP53 mRNA | CTD | PMID:15346788 |
Tp53 | Rat | ouabain | multiple interactions | ISO | RGD:70502 | 6480464 | Ouabain results in decreased expression of and results in increased phosphorylation of TP53 protein | CTD | PMID:31436044 |
Tp53 | Rat | oxaliplatin | multiple interactions | ISO | RGD:70502 | 6480464 | [pifithrin results in decreased activity of TP53 protein] results in decreased susceptibility to [Oxaliplatin results more ... | CTD | PMID:16227409|PMID:19015155|PMID:19728331|PMID:19735649|PMID:20708607 |
Tp53 | Rat | oxaliplatin | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to oxaliplatin | CTD | PMID:16227409 |
Tp53 | Rat | oxaliplatin | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to oxaliplatin | CTD | PMID:15041737 |
Tp53 | Rat | oxaliplatin | affects localization | ISO | RGD:70502 | 6480464 | oxaliplatin affects the localization of TP53 protein modified form | CTD | PMID:19735649 |
Tp53 | Rat | oxaliplatin | increases expression | ISO | RGD:70502 | 6480464 | oxaliplatin results in increased expression of TP53 protein; oxaliplatin results in increased expression of TP53 more ... | CTD | PMID:19015155|PMID:19728331|PMID:19735649|PMID:20708607 |
Tp53 | Rat | oxamyl | affects activity | ISO | RGD:70502 | 6480464 | oxamyl metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | oxfendazole | decreases expression | EXP | | 6480464 | oxfendazole results in decreased expression of TP53 mRNA | CTD | PMID:26558467 |
Tp53 | Rat | oxidopamine | multiple interactions | EXP | | 6480464 | SN50 peptide inhibits the reaction [Oxidopamine results in increased expression of TP53 protein] | CTD | PMID:17368433 |
Tp53 | Rat | oxidopamine | increases expression | EXP | | 6480464 | Oxidopamine results in increased expression of TP53 protein | CTD | PMID:17368433 |
Tp53 | Rat | oxirane | increases expression | ISO | RGD:11440 | 6480464 | Ethylene Oxide results in increased expression of TRP53 protein | CTD | PMID:17162533 |
Tp53 | Rat | oxybenzone | decreases expression | EXP | | 6480464 | oxybenzone results in decreased expression of TP53 mRNA | CTD | PMID:30316929 |
Tp53 | Rat | oxycarboxin | affects activity | ISO | RGD:70502 | 6480464 | oxycarboxin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of TP53 mRNA | CTD | PMID:36437433 |
Tp53 | Rat | ozone | affects expression | ISO | RGD:70502 | 6480464 | Ozone affects the expression of TP53 mRNA | CTD | PMID:35936665 |
Tp53 | Rat | ozone | multiple interactions | ISO | RGD:70502 | 6480464 | [Oxygen co-treated with Ozone] inhibits the reaction [Cannabidiol results in increased expression of TP53 mRNA]; more ... | CTD | PMID:32992648 |
Tp53 | Rat | ozone | multiple interactions | EXP | | 6480464 | Ozone inhibits the reaction [sodium arsenite results in decreased expression of TP53 mRNA] | CTD | PMID:36437433 |
Tp53 | Rat | p-menthan-3-ol | increases expression | ISO | RGD:70502 | 6480464 | Menthol results in increased expression of TP53 mRNA | CTD | PMID:26760959 |
Tp53 | Rat | p-tert-Amylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of TP53 mRNA | CTD | PMID:17011747 |
Tp53 | Rat | p-tert-Amylphenol | increases phosphorylation | ISO | RGD:70502 | 6480464 | 4-tert-octylphenol results in increased phosphorylation of TP53 protein | CTD | PMID:32466334 |
Tp53 | Rat | paclitaxel | multiple interactions | ISO | RGD:70502 | 6480464 | [Doxorubicin co-treated with Paclitaxel] results in increased expression of TP53 protein; [Paclitaxel co-treated with Carboplatin more ... | CTD | PMID:12440809|PMID:16168113|PMID:16413505|PMID:16601104|PMID:33002289|PMID:33422634 |
Tp53 | Rat | paclitaxel | increases expression | ISO | RGD:11440 | 6480464 | Paclitaxel results in increased expression of TP53 protein | CTD | PMID:9231689 |
Tp53 | Rat | paclitaxel | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in decreased susceptibility to Paclitaxel | CTD | PMID:15990222|PMID:16734730 |
Tp53 | Rat | paclitaxel | increases expression | ISO | RGD:70502 | 6480464 | [Paclitaxel results in increased expression of TP53 protein] which results in increased expression of BAX more ... | CTD | PMID:11774260|PMID:12082016|PMID:14991574|PMID:15990222|PMID:16601104|PMID:18451153|PMID:18516295|PMID:19815708|PMID:33002289|PMID:33422634|PMID:9041188 |
Tp53 | Rat | paclitaxel | decreases expression | ISO | RGD:70502 | 6480464 | Paclitaxel results in decreased expression of TP53 protein | CTD | PMID:11774260 |
Tp53 | Rat | paeoniflorin | multiple interactions | ISO | RGD:70502 | 6480464 | peoniflorin inhibits the reaction [cobaltous chloride results in increased expression of TP53 mRNA] | CTD | PMID:22269387 |
Tp53 | Rat | palbociclib | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein mutant form results in decreased susceptibility to palbociclib | CTD | PMID:21278246 |
Tp53 | Rat | panobinostat | multiple interactions | ISO | RGD:70502 | 6480464 | [panobinostat co-treated with SRT2183] results in increased acetylation of TP53 protein | CTD | PMID:23681230 |
Tp53 | Rat | panobinostat | increases acetylation | ISO | RGD:70502 | 6480464 | panobinostat results in increased acetylation of TP53 protein | CTD | PMID:23681230 |
Tp53 | Rat | para-Cresidine | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein mutant form results in increased susceptibility to cresidine | CTD | PMID:12512871 |
Tp53 | Rat | para-Nitrosodiphenylamine | affects activity | ISO | RGD:70502 | 6480464 | 4-nitroso-N-phenylaniline affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | paracetamol | multiple interactions | EXP | | 6480464 | Acetaminophen promotes the reaction [MDM2 protein binds to TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction more ... | CTD | PMID:16330492 |
Tp53 | Rat | paracetamol | increases expression | ISO | RGD:11440 | 6480464 | Acetaminophen results in increased expression of TRP53 protein | CTD | PMID:11461765|PMID:22939915|PMID:25956474 |
Tp53 | Rat | paracetamol | decreases expression | ISO | RGD:70502 | 6480464 | Acetaminophen results in decreased expression of TP53 mRNA | CTD | PMID:21420995|PMID:25704631 |
Tp53 | Rat | paracetamol | increases activity | EXP | | 6480464 | Acetaminophen results in increased activity of TP53 protein | CTD | PMID:25858767 |
Tp53 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TP53 mRNA | CTD | PMID:21807079 |
Tp53 | Rat | paracetamol | multiple interactions | ISO | RGD:11440 | 6480464 | 4-aminobenzamide promotes the reaction [Acetaminophen results in decreased expression of TRP53 protein]; Acetaminophen results in more ... | CTD | PMID:11461765|PMID:22939915|PMID:25319358|PMID:25956474 |
Tp53 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TP53 mRNA; Acetaminophen results in decreased expression of TP53 more ... | CTD | PMID:16330492|PMID:33387578 |
Tp53 | Rat | paracetamol | increases phosphorylation | EXP | | 6480464 | Acetaminophen results in increased phosphorylation of TP53 protein | CTD | PMID:16330492 |
Tp53 | Rat | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of TP53 mRNA | CTD | PMID:16701773 |
Tp53 | Rat | paraoxon | increases expression | ISO | RGD:11440 | 6480464 | Paraoxon results in increased expression of TRP53 protein | CTD | PMID:12831782 |
Tp53 | Rat | paraoxon | multiple interactions | ISO | RGD:11440 | 6480464 | benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane analog inhibits the reaction [Paraoxon results in increased expression of TRP53 protein] | CTD | PMID:12831782 |
Tp53 | Rat | Paraoxon-methyl | increases expression | ISO | RGD:70502 | 6480464 | methylparaoxon results in increased expression of TP53 mRNA | CTD | PMID:18418871 |
Tp53 | Rat | Paraoxon-methyl | affects activity | ISO | RGD:70502 | 6480464 | methylparaoxon metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | paraquat | multiple interactions | ISO | RGD:70502 | 6480464 | Paraquat promotes the reaction [Trientine results in increased phosphorylation of TP53 protein] | CTD | PMID:11369509 |
Tp53 | Rat | paraquat | increases phosphorylation | ISO | RGD:11440 | 6480464 | Paraquat results in increased phosphorylation of TRP53 protein | CTD | PMID:34811946 |
Tp53 | Rat | paraquat | increases expression | ISO | RGD:11440 | 6480464 | Paraquat results in increased expression of TP53; Paraquat results in increased expression of TRP53 mRNA | CTD | PMID:28012437|PMID:28428137|PMID:31911963 |
Tp53 | Rat | paraquat | increases expression | ISO | RGD:70502 | 6480464 | Paraquat results in increased expression of TP53 mRNA; Paraquat results in increased expression of TP53 more ... | CTD | PMID:10969820|PMID:15162845|PMID:18253895|PMID:18836921|PMID:19526292|PMID:24060684|PMID:28428137|PMID:34097952|PMID:35641671 |
Tp53 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of TP53 mRNA | CTD | PMID:18198484 |
Tp53 | Rat | paraquat | multiple interactions | ISO | RGD:11440 | 6480464 | 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TRP53 protein]; more ... | CTD | PMID:10969820|PMID:20964710|PMID:23963992|PMID:23985028|PMID:28012437|PMID:31911963|PMID:34811946 |
Tp53 | Rat | paraquat | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein results in increased susceptibility to Paraquat | CTD | PMID:10969820 |
Tp53 | Rat | paraquat | increases phosphorylation | EXP | | 6480464 | Paraquat results in increased phosphorylation of TP53 protein | CTD | PMID:20478973 |
Tp53 | Rat | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of TP53 mRNA; Paraquat results in increased expression of TP53 more ... | CTD | PMID:17561093|PMID:22678742|PMID:24912633 |
Tp53 | Rat | paraquat | increases phosphorylation | ISO | RGD:70502 | 6480464 | Paraquat results in increased phosphorylation of TP53 protein | CTD | PMID:11369509 |
Tp53 | Rat | paraquat | multiple interactions | EXP | | 6480464 | [7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat results in more ... | CTD | PMID:17561093|PMID:20478973|PMID:22678742 |
Tp53 | Rat | parathion | multiple interactions | ISO | RGD:70502 | 6480464 | [Parathion co-treated with Estradiol] results in increased expression of TP53 protein mutant form; Atropine inhibits more ... | CTD | PMID:12762645|PMID:17622325 |
Tp53 | Rat | parathion | affects activity | ISO | RGD:70502 | 6480464 | Parathion metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | parathion | increases expression | ISO | RGD:70502 | 6480464 | Parathion results in increased expression of TP53 protein; Parathion results in increased expression of TP53 more ... | CTD | PMID:12762645|PMID:17390078|PMID:17622325|PMID:19787260 |
Tp53 | Rat | parathion-methyl | increases expression | ISO | RGD:70502 | 6480464 | Methyl Parathion results in increased expression of TP53 mRNA | CTD | PMID:18418871 |
Tp53 | Rat | parathion-methyl | affects activity | ISO | RGD:70502 | 6480464 | Methyl Parathion metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | parthenolide | increases expression | ISO | RGD:70502 | 6480464 | parthenolide results in increased expression of TP53 protein | CTD | PMID:16024633 |
Tp53 | Rat | patulin | increases expression | ISO | RGD:11440 | 6480464 | Patulin results in increased expression of TRP53; Patulin results in increased expression of TRP53 protein | CTD | PMID:19000704|PMID:26095701 |
Tp53 | Rat | patulin | increases expression | ISO | RGD:70502 | 6480464 | Patulin results in increased expression of TP53 protein | CTD | PMID:19744505 |
Tp53 | Rat | pazopanib | multiple interactions | ISO | RGD:70502 | 6480464 | NFE2L2 protein affects the reaction [pazopanib results in increased expression of TP53 mRNA]; NFE2L2 protein more ... | CTD | PMID:38613465 |
Tp53 | Rat | pazopanib | increases expression | ISO | RGD:70502 | 6480464 | pazopanib results in increased expression of TP53 mRNA; pazopanib results in increased expression of TP53 more ... | CTD | PMID:38613465 |
Tp53 | Rat | PCB138 | multiple interactions | ISO | RGD:11440 | 6480464 | [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... | CTD | PMID:25510870 |
Tp53 | Rat | PD 0325901 | multiple interactions | ISO | RGD:11440 | 6480464 | [mirdametinib co-treated with MK 2206] results in increased expression of and results in increased phosphorylation more ... | CTD | PMID:28691888 |
Tp53 | Rat | PD 168393 | multiple interactions | ISO | RGD:70502 | 6480464 | [PD168393 co-treated with Paclitaxel] results in increased expression of TP53 protein | CTD | PMID:16413505 |
Tp53 | Rat | pectolinarigenin | increases expression | ISO | RGD:70502 | 6480464 | pectolinarigenin results in increased expression of TP53 protein | CTD | PMID:37393350 |
Tp53 | Rat | pectolinarigenin | multiple interactions | ISO | RGD:70502 | 6480464 | TOP2A protein affects the reaction [pectolinarigenin results in increased expression of TP53 protein] | CTD | PMID:37393350 |
Tp53 | Rat | pemetrexed | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the reaction [Pemetrexed results in increased expression of FAS protein] | CTD | PMID:15161716 |
Tp53 | Rat | pemetrexed | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Pemetrexed | CTD | PMID:17339891 |
Tp53 | Rat | pentachlorophenol | affects expression | ISO | RGD:70502 | 6480464 | Pentachlorophenol affects the expression of TP53 protein | CTD | PMID:12724925 |
Tp53 | Rat | pentachlorophenol | affects activity | ISO | RGD:70502 | 6480464 | Pentachlorophenol affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | pentachlorophenol | multiple interactions | ISO | RGD:11440 | 6480464 | Pentachlorophenol inhibits the reaction [lucidin 3-O-beta-primveroside results in increased expression of TRP53 protein modified form] | CTD | PMID:30874336 |
Tp53 | Rat | pentachlorophenol | increases expression | ISO | RGD:11440 | 6480464 | Pentachlorophenol results in increased expression of TRP53 protein | CTD | PMID:16823072 |
Tp53 | Rat | pentachlorophenol | increases phosphorylation | EXP | | 6480464 | Pentachlorophenol results in increased phosphorylation of TP53 protein | CTD | PMID:19442831 |
Tp53 | Rat | pentamidine | multiple interactions | ISO | RGD:70502 | 6480464 | Pentamidine inhibits the reaction [KAT5 protein results in increased acetylation of TP53 protein] | CTD | PMID:20144237 |
Tp53 | Rat | pentanal | decreases expression | ISO | RGD:70502 | 6480464 | pentanal results in decreased expression of TP53 mRNA | CTD | PMID:26079696 |
Tp53 | Rat | pentetic acid | multiple interactions | ISO | RGD:70502 | 6480464 | Pentetic Acid inhibits the reaction [pyrithione zinc results in increased expression of TP53 protein]; Pentetic more ... | CTD | PMID:21557991 |
Tp53 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | RGD:11440 | 6480464 | perfluorohexanesulfonic acid results in increased expression of TRP53 mRNA | CTD | PMID:37995155 |
Tp53 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | RGD:70502 | 6480464 | perfluorohexanesulfonic acid results in decreased expression of TP53 protein | CTD | PMID:34843762 |
Tp53 | Rat | perfluorooctane-1-sulfonic acid | increases expression | ISO | RGD:70502 | 6480464 | perfluorooctane sulfonic acid results in increased expression of TP53 mRNA; perfluorooctane sulfonic acid results in more ... | CTD | PMID:19468714|PMID:24301089|PMID:32700164 |
Tp53 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | RGD:11440 | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TRP53 mRNA | CTD | PMID:36331819 |
Tp53 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | RGD:70502 | 6480464 | perfluorooctane sulfonic acid results in decreased expression of TP53 protein | CTD | PMID:29063134 |
Tp53 | Rat | perfluorooctane-1-sulfonic acid | increases expression | ISO | RGD:11440 | 6480464 | perfluorooctane sulfonic acid results in increased expression of TRP53 mRNA | CTD | PMID:21115943 |
Tp53 | Rat | perfluorooctane-1-sulfonic acid | increases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in increased expression of TP53 mRNA; perfluorooctane sulfonic acid results in more ... | CTD | PMID:24616003 |
Tp53 | Rat | perfluorooctanoic acid | increases expression | ISO | RGD:70502 | 6480464 | perfluorooctanoic acid results in increased expression of TP53 mRNA; perfluorooctanoic acid results in increased expression more ... | CTD | PMID:25868421|PMID:34765786 |
Tp53 | Rat | perfluorooctanoic acid | increases phosphorylation | ISO | RGD:11440 | 6480464 | perfluorooctanoic acid results in increased phosphorylation of TRP53 protein | CTD | PMID:37044272 |
Tp53 | Rat | perfluorooctanoic acid | increases expression | ISO | RGD:11440 | 6480464 | perfluorooctanoic acid results in increased expression of TRP53 mRNA; perfluorooctanoic acid results in increased expression more ... | CTD | PMID:28219760|PMID:37044272 |
Tp53 | Rat | pergolide | multiple interactions | ISO | RGD:70502 | 6480464 | Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results more ... | CTD | PMID:15081873 |
Tp53 | Rat | pergolide | multiple interactions | ISO | RGD:11440 | 6480464 | Pergolide inhibits the reaction [Levodopa results in increased expression of TRP53 protein] | CTD | PMID:15672541 |
Tp53 | Rat | perifosine | multiple interactions | ISO | RGD:70502 | 6480464 | perifosine inhibits the reaction [cyadox results in increased expression of TP53 mRNA]; perifosine inhibits the more ... | CTD | PMID:30265530 |
Tp53 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TP53 protein | CTD | PMID:12587291 |
Tp53 | Rat | phenethyl caffeate | multiple interactions | ISO | RGD:70502 | 6480464 | caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of TP53 more ... | CTD | PMID:17204746|PMID:22692362|PMID:26056802 |
Tp53 | Rat | phenethyl caffeate | multiple interactions | EXP | | 6480464 | caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of TP53 mRNA] | CTD | PMID:20360939 |
Tp53 | Rat | phenethyl isothiocyanate | increases expression | ISO | RGD:70502 | 6480464 | phenethyl isothiocyanate results in increased expression of TP53 protein | CTD | PMID:16054126 |
Tp53 | Rat | phenindione | increases degradation | ISO | RGD:70502 | 6480464 | Phenindione results in increased degradation of TP53 protein | CTD | PMID:14634213 |
Tp53 | Rat | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of TP53 mRNA; Phenobarbital results in decreased expression of TP53 more ... | CTD | PMID:25247799 |
Tp53 | Rat | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of TP53 mRNA | CTD | PMID:23273579 |
Tp53 | Rat | phenobarbital | multiple interactions | ISO | RGD:11440 | 6480464 | Phenobarbital inhibits the reaction [MYC protein results in increased expression of TRP53 protein] | CTD | PMID:10449034 |
Tp53 | Rat | phenobarbital | multiple interactions | EXP | | 6480464 | [Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA; [Phenobarbital co-treated with Diethylnitrosamine] more ... | CTD | PMID:11751435|PMID:22436021 |
Tp53 | Rat | phenol | increases expression | ISO | RGD:11440 | 6480464 | Phenol results in increased expression of TRP53 protein | CTD | PMID:9667752 |
Tp53 | Rat | phenylmercury acetate | affects activity | ISO | RGD:70502 | 6480464 | Phenylmercuric Acetate affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | phenytoin | increases expression | ISO | RGD:70502 | 6480464 | Phenytoin results in increased expression of TP53 mRNA | CTD | PMID:11134551 |
Tp53 | Rat | PhIP | affects expression | ISO | RGD:70502 | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of TP53 mRNA | CTD | PMID:32342131 |
Tp53 | Rat | PhIP | increases phosphorylation | ISO | RGD:70502 | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of TP53 protein | CTD | PMID:32466334 |
Tp53 | Rat | PhIP | increases expression | ISO | RGD:70502 | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of TP53 protein | CTD | PMID:11425520|PMID:15635149|PMID:17156947|PMID:23810796 |
Tp53 | Rat | PhIP | multiple interactions | ISO | RGD:70502 | 6480464 | myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of TP53 mRNA] | CTD | PMID:32342131 |
Tp53 | Rat | phloretin | multiple interactions | EXP | | 6480464 | [Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 protein] | CTD | PMID:34896434 |
Tp53 | Rat | phloretin | multiple interactions | ISO | RGD:70502 | 6480464 | [Ruthenium binds to Phloretin] which results in increased expression of TP53 protein | CTD | PMID:34896434 |
Tp53 | Rat | phorate | increases expression | EXP | | 6480464 | Phorate results in increased expression of TP53 mRNA; Phorate results in increased expression of TP53 more ... | CTD | PMID:22197610 |
Tp53 | Rat | phorate | affects activity | ISO | RGD:70502 | 6480464 | Phorate metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | phorbol 13-acetate 12-myristate | decreases expression | ISO | RGD:70502 | 6480464 | Tetradecanoylphorbol Acetate results in decreased expression of TP53 protein | CTD | PMID:10910098 |
Tp53 | Rat | phorbol 13-acetate 12-myristate | increases phosphorylation | ISO | RGD:70502 | 6480464 | Tetradecanoylphorbol Acetate results in increased phosphorylation of TP53 protein | CTD | PMID:8076368|PMID:8927716 |
Tp53 | Rat | phorbol 13-acetate 12-myristate | increases phosphorylation | EXP | | 6480464 | Tetradecanoylphorbol Acetate results in increased phosphorylation of TP53 protein | CTD | PMID:8076368 |
Tp53 | Rat | phorbol 13-acetate 12-myristate | multiple interactions | ISO | RGD:70502 | 6480464 | Tetradecanoylphorbol Acetate inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased more ... | CTD | PMID:15542774 |
Tp53 | Rat | phosalone | increases expression | EXP | | 6480464 | phosalone results in increased expression of TP53 mRNA; phosalone results in increased expression of TP53 more ... | CTD | PMID:27965107 |
Tp53 | Rat | phosalone | multiple interactions | EXP | | 6480464 | Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 mRNA]; Ellagic Acid more ... | CTD | PMID:27965107 |
Tp53 | Rat | phosmet | affects activity | ISO | RGD:70502 | 6480464 | Phosmet metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | phosphamidon | affects activity | ISO | RGD:70502 | 6480464 | Phosphamidon metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | phosphatidylcholine | multiple interactions | ISO | RGD:70502 | 6480464 | Phosphatidylcholines inhibits the reaction [rubitecan results in increased expression of TP53 protein] | CTD | PMID:21695227 |
Tp53 | Rat | phoxim | affects activity | ISO | RGD:70502 | 6480464 | phoxim metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | phthalaldehyde | affects activity | ISO | RGD:70502 | 6480464 | o-Phthalaldehyde affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | picoxystrobin | increases activity | ISO | RGD:70502 | 6480464 | picoxystrobin results in increased activity of TP53 protein | CTD | PMID:30818834 |
Tp53 | Rat | picoxystrobin | affects activity | ISO | RGD:70502 | 6480464 | picoxystrobin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | pifithrin-alpha hydrobromide | decreases expression | ISO | RGD:70502 | 6480464 | pifithrin results in decreased expression of TP53 protein | CTD | PMID:12893085|PMID:16467109|PMID:16777994 |
Tp53 | Rat | pifithrin-alpha hydrobromide | decreases activity | ISO | RGD:11440 | 6480464 | pifithrin results in decreased activity of TRP53 protein | CTD | PMID:10702639|PMID:11914272|PMID:15976193 |
Tp53 | Rat | pifithrin-alpha hydrobromide | multiple interactions | EXP | | 6480464 | pifithrin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TP53 protein]; pifithrin inhibits the more ... | CTD | PMID:11279278|PMID:12143041|PMID:12665479|PMID:13679428|PMID:15144874|PMID:15315938|PMID:16005925|PMID:16687611|PMID:17487067|PMID:18775851|PMID:24567336|PMID:29484840|PMID:30009776|PMID:31157505|PMID:31618665|PMID:32924446|PMID:33031904|PMID:33737050|PMID:34091999 |
Tp53 | Rat | pifithrin-alpha hydrobromide | decreases activity | ISO | RGD:70502 | 6480464 | pifithrin results in decreased activity of TP53 protein | CTD | PMID:20878077|PMID:22886373|PMID:25956474|PMID:26259609 |
Tp53 | Rat | pifithrin-alpha hydrobromide | decreases activity | EXP | | 6480464 | pifithrin results in decreased activity of TP53 protein | CTD | PMID:11279278|PMID:12143041|PMID:13679428 |
Tp53 | Rat | pifithrin-alpha hydrobromide | affects expression | ISO | RGD:11440 | 6480464 | pifithrin affects the expression of TRP53 protein | CTD | PMID:16087272 |
Tp53 | Rat | pifithrin-alpha hydrobromide | decreases expression | EXP | | 6480464 | pifithrin results in decreased expression of TP53 mRNA; pifithrin results in decreased expression of TP53 more ... | CTD | PMID:18364113|PMID:34091999 |
Tp53 | Rat | pifithrin-alpha hydrobromide | multiple interactions | ISO | RGD:11440 | 6480464 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pifithrin results in increased expression of and results in increased activity more ... | CTD | PMID:11931974|PMID:12413886|PMID:12884365|PMID:14766674|PMID:15976193|PMID:17670903|PMID:18550754|PMID:18940243|PMID:21593185|PMID:22491426|PMID:23376438|PMID:33162236|PMID:35908932 |
Tp53 | Rat | pifithrin-alpha hydrobromide | multiple interactions | ISO | RGD:70502 | 6480464 | [pifithrin co-treated with cobaltous chloride] results in increased expression of and affects the localization of more ... | CTD | PMID:11889192|PMID:15735102|PMID:16258175|PMID:16357363|PMID:16467109|PMID:16777994|PMID:16814113|PMID:16882877|PMID:16946128|PMID:19098008|PMID:19706164|PMID:19735649|PMID:20045437|PMID:20708607|PMID:21660965|PMID:21810437|PMID:22226932|PMID:22886373|PMID:22983795|PMID:23152798|PMID:23380477|PMID:23665932|PMID:24535435|PMID:25435374|PMID:26884717|PMID:28757460|PMID:30543781|PMID:32540572|PMID:32687844|PMID:36982514 |
Tp53 | Rat | pifithrin-alpha hydrobromide | decreases phosphorylation | ISO | RGD:70502 | 6480464 | pifithrin results in decreased phosphorylation of TP53 protein | CTD | PMID:19735649|PMID:21810437 |
Tp53 | Rat | pinostrobin | increases expression | ISO | RGD:70502 | 6480464 | pinostrobin results in increased expression of TP53 mRNA | CTD | PMID:37208425 |
Tp53 | Rat | pinosylvin | increases expression | ISO | RGD:70502 | 6480464 | pinosylvin results in increased expression of TP53 protein | CTD | PMID:23333577 |
Tp53 | Rat | piperine | multiple interactions | ISO | RGD:70502 | 6480464 | [piperine co-treated with Curcumin] results in decreased expression of TP53 protein | CTD | PMID:30935902 |
Tp53 | Rat | Pirarubicin | affects activity | ISO | RGD:70502 | 6480464 | pirarubicin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | pirimicarb | affects activity | ISO | RGD:70502 | 6480464 | pirimicarb metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Pirimiphos-ethyl | affects activity | ISO | RGD:70502 | 6480464 | pirimiphos-ethyl metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of TP53 mRNA | CTD | PMID:22484513 |
Tp53 | Rat | piroxicam | multiple interactions | ISO | RGD:70502 | 6480464 | Piroxicam promotes the reaction [Cisplatin results in increased expression of TP53 protein] | CTD | PMID:21858171 |
Tp53 | Rat | PK-11195 | multiple interactions | ISO | RGD:11440 | 6480464 | PK 11195 inhibits the reaction [Rotenone affects the localization of TRP53 protein] | CTD | PMID:23899557 |
Tp53 | Rat | platycodin D | decreases expression | ISO | RGD:70502 | 6480464 | platycodin D results in decreased expression of TP53 protein mutant form | CTD | PMID:27432230 |
Tp53 | Rat | plumbagin | increases expression | EXP | | 6480464 | plumbagin results in increased expression of TP53 protein | CTD | PMID:34302802 |
Tp53 | Rat | poly(I:C) | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the reaction [Poly I-C affects the localization of RELA protein]; TP53 protein more ... | CTD | PMID:18779317|PMID:20367642 |
Tp53 | Rat | poly(vinylpyrrolidone) | multiple interactions | ISO | RGD:70502 | 6480464 | [Silver co-treated with Povidone] affects the phosphorylation of TP53 protein; [Silver co-treated with Povidone] results more ... | CTD | PMID:27387714 |
Tp53 | Rat | polymyxin B2 | multiple interactions | ISO | RGD:70502 | 6480464 | baicalein inhibits the reaction [Polymyxin B results in increased acetylation of TP53 protein]; Polymyxin B more ... | CTD | PMID:37088170|PMID:37354967 |
Tp53 | Rat | ponatinib | increases expression | ISO | RGD:11440 | 6480464 | ponatinib results in increased expression of TRP53 protein | CTD | PMID:34699866 |
Tp53 | Rat | ponatinib | multiple interactions | ISO | RGD:11440 | 6480464 | [gossypol acetic acid results in increased abundance of Gossypol] promotes the reaction [ponatinib results in more ... | CTD | PMID:34699866 |
Tp53 | Rat | potassium bromate | increases phosphorylation | EXP | | 6480464 | potassium bromate results in increased phosphorylation of TP53 protein | CTD | PMID:20067818|PMID:25015661 |
Tp53 | Rat | potassium bromate | multiple interactions | EXP | | 6480464 | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]; Ascorbic Acid more ... | CTD | PMID:20067818 |
Tp53 | Rat | potassium bromate | increases phosphorylation | ISO | RGD:70502 | 6480464 | potassium bromate results in increased phosphorylation of TP53 protein | CTD | PMID:20067818 |
Tp53 | Rat | potassium bromate | multiple interactions | ISO | RGD:70502 | 6480464 | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]; Ascorbic Acid more ... | CTD | PMID:20067818 |
Tp53 | Rat | potassium chloride | multiple interactions | EXP | | 6480464 | [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression more ... | CTD | PMID:22228705 |
Tp53 | Rat | potassium chromate | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein modified form]; more ... | CTD | PMID:12727806|PMID:25977998 |
Tp53 | Rat | potassium chromate | increases expression | ISO | RGD:70502 | 6480464 | potassium chromate(VI) results in increased expression of TP53 protein; potassium chromate(VI) results in increased expression more ... | CTD | PMID:25977998 |
Tp53 | Rat | potassium dichromate | multiple interactions | EXP | | 6480464 | [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide co-treated with [Potassium Dichromate results in increased abundance of chromium hexavalent ion]] results in more ... | CTD | PMID:18563748|PMID:21262251|PMID:25245570|PMID:35307491 |
Tp53 | Rat | potassium dichromate | affects activity | ISO | RGD:70502 | 6480464 | Potassium Dichromate affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | potassium dichromate | increases expression | EXP | | 6480464 | Potassium Dichromate results in increased expression of TP53 mRNA; Potassium Dichromate results in increased expression more ... | CTD | PMID:18547707|PMID:18563748|PMID:21262251|PMID:25245570|PMID:26348139 |
Tp53 | Rat | potassium dichromate | increases phosphorylation | ISO | RGD:70502 | 6480464 | Potassium Dichromate results in increased phosphorylation of TP53 protein | CTD | PMID:20493934 |
Tp53 | Rat | potassium dichromate | multiple interactions | ISO | RGD:70502 | 6480464 | nickel sulfate inhibits the reaction [Potassium Dichromate results in increased phosphorylation of TP53 protein] | CTD | PMID:20493934 |
Tp53 | Rat | potassium dichromate | increases expression | ISO | RGD:11440 | 6480464 | Potassium Dichromate results in increased expression of TRP53 protein | CTD | PMID:19219935 |
Tp53 | Rat | potassium dichromate | increases localization | EXP | | 6480464 | Potassium Dichromate results in increased localization of TP53 protein modified form | CTD | PMID:21262251 |
Tp53 | Rat | potassium iodide | increases expression | EXP | | 6480464 | Potassium Iodide results in increased expression of TP53 protein | CTD | PMID:32593569 |
Tp53 | Rat | pravastatin | multiple interactions | ISO | RGD:70502 | 6480464 | [Pravastatin results in increased phosphorylation of MDM2 protein] which results in increased degradation of TP53 more ... | CTD | PMID:15625077|PMID:20884875 |
Tp53 | Rat | pravastatin | multiple interactions | EXP | | 6480464 | Pravastatin inhibits the reaction [Cisplatin results in increased expression of TP53 protein] | CTD | PMID:20650967 |
Tp53 | Rat | proanthocyanidin | increases expression | ISO | RGD:70502 | 6480464 | Proanthocyanidins results in increased expression of TP53 mRNA; Proanthocyanidins results in increased expression of TP53 more ... | CTD | PMID:29654773 |
Tp53 | Rat | procyanidin | decreases phosphorylation | ISO | RGD:70502 | 6480464 | procyanidin results in decreased phosphorylation of TP53 protein | CTD | PMID:15827326 |
Tp53 | Rat | procyanidin B1 | decreases expression | ISO | RGD:11440 | 6480464 | procyanidin B1 results in decreased expression of TRP53 mRNA; procyanidin B1 results in decreased expression more ... | CTD | PMID:34684730 |
Tp53 | Rat | progesterone | decreases expression | ISO | RGD:70502 | 6480464 | Progesterone results in decreased expression of TP53 protein | CTD | PMID:14529565 |
Tp53 | Rat | progesterone | multiple interactions | ISO | RGD:11440 | 6480464 | [Progesterone co-treated with Estrogens] results in increased expression of TRP53 mRNA; IGF1 protein inhibits the more ... | CTD | PMID:18562952 |
Tp53 | Rat | progesterone | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with Methylnitrosourea co-treated with Progesterone] results in decreased expression of TP53 mRNA; [Methylnitrosourea more ... | CTD | PMID:20732338 |
Tp53 | Rat | progesterone | multiple interactions | ISO | RGD:70502 | 6480464 | bisphenol A inhibits the reaction [Progesterone results in increased expression of TP53 mRNA]; TP53 mutant more ... | CTD | PMID:18850315|PMID:37009741 |
Tp53 | Rat | progesterone | increases expression | ISO | RGD:70502 | 6480464 | Progesterone results in increased expression of TP53 mRNA; Progesterone results in increased expression of TP53 more ... | CTD | PMID:18850315|PMID:37009741 |
Tp53 | Rat | progesterone | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein results in increased susceptibility to Progesterone | CTD | PMID:11053243 |
Tp53 | Rat | progesterone | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Progesterone | CTD | PMID:14529565 |
Tp53 | Rat | Promecarb | affects activity | ISO | RGD:70502 | 6480464 | promecarb metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | promethazine | decreases expression | EXP | | 6480464 | Promethazine results in decreased expression of TP53 mRNA | CTD | PMID:26011634 |
Tp53 | Rat | propachlor | affects activity | ISO | RGD:70502 | 6480464 | propachlor affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | propanal | decreases expression | ISO | RGD:70502 | 6480464 | propionaldehyde results in decreased expression of TP53 mRNA | CTD | PMID:26079696 |
Tp53 | Rat | propetamphos | affects activity | ISO | RGD:70502 | 6480464 | propetamphos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | propofol | multiple interactions | EXP | | 6480464 | Propofol inhibits the reaction [Doxorubicin results in increased expression of TP53 protein] | CTD | PMID:22015447 |
Tp53 | Rat | propofol | increases expression | ISO | RGD:70502 | 6480464 | Propofol results in increased expression of TP53 protein | CTD | PMID:28804952 |
Tp53 | Rat | propylparaben | increases expression | ISO | RGD:70502 | 6480464 | propylparaben results in increased expression of TP53 mRNA; propylparaben results in increased expression of TP53 more ... | CTD | PMID:24481588 |
Tp53 | Rat | prothiofos | affects activity | ISO | RGD:70502 | 6480464 | prothiophos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Ptaquiloside | decreases expression | ISO | RGD:70502 | 6480464 | ptaquiloside results in decreased expression of TP53 mRNA | CTD | PMID:22143989 |
Tp53 | Rat | Ptaquiloside | increases expression | ISO | RGD:70502 | 6480464 | ptaquiloside results in increased expression of TP53 mRNA; ptaquiloside results in increased expression of TP53 more ... | CTD | PMID:22143989 |
Tp53 | Rat | pterostilbene | increases expression | ISO | RGD:70502 | 6480464 | pterostilbene results in increased expression of TP53 mRNA | CTD | PMID:20152895 |
Tp53 | Rat | purine-6-thiol | affects activity | ISO | RGD:70502 | 6480464 | Mercaptopurine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | pyrazophos | affects activity | ISO | RGD:70502 | 6480464 | pyrazophos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | pyrene | multiple interactions | ISO | RGD:11440 | 6480464 | pyrene inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased phosphorylation of TRP53 protein]; pyrene promotes the more ... | CTD | PMID:22120587|PMID:35908932 |
Tp53 | Rat | pyrene | increases expression | ISO | RGD:11440 | 6480464 | pyrene results in increased expression of TRP53 protein | CTD | PMID:22120587 |
Tp53 | Rat | Pyridostigmine bromide | multiple interactions | EXP | | 6480464 | [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TP53 protein | CTD | PMID:12587291 |
Tp53 | Rat | pyrogallol | multiple interactions | ISO | RGD:70502 | 6480464 | pyrazolanthrone inhibits the reaction [Pyrogallol results in increased expression of TP53 protein]; SB 203580 inhibits more ... | CTD | PMID:20191265 |
Tp53 | Rat | pyrogallol | increases expression | ISO | RGD:70502 | 6480464 | Pyrogallol results in increased expression of TP53 protein | CTD | PMID:20191265 |
Tp53 | Rat | pyrroles | multiple interactions | ISO | RGD:70502 | 6480464 | pifithrin inhibits the reaction [Pyrroles analog results in increased phosphorylation of TP53 protein] | CTD | PMID:30543781 |
Tp53 | Rat | pyrroles | increases phosphorylation | ISO | RGD:70502 | 6480464 | Pyrroles analog results in increased phosphorylation of TP53 protein | CTD | PMID:30543781 |
Tp53 | Rat | pyrrolidine dithiocarbamate | multiple interactions | ISO | RGD:70502 | 6480464 | [pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of more ... | CTD | PMID:11964141 |
Tp53 | Rat | pyrrolidine dithiocarbamate | multiple interactions | ISO | RGD:11440 | 6480464 | pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased more ... | CTD | PMID:25559736 |
Tp53 | Rat | pyrrolidine dithiocarbamate | decreases expression | EXP | | 6480464 | pyrrolidine dithiocarbamic acid results in decreased expression of TP53 protein | CTD | PMID:16049548 |
Tp53 | Rat | pyruvic acid | multiple interactions | EXP | | 6480464 | [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in more ... | CTD | PMID:25997894 |
Tp53 | Rat | quartz | increases expression | EXP | | 6480464 | Quartz results in increased expression of TRP53 protein | CTD | PMID:11306444 |
Tp53 | Rat | quartz | multiple interactions | ISO | RGD:70502 | 6480464 | FOSL1 promotes the reaction [Quartz results in decreased expression of TP53 protein]; MIR34C inhibits the more ... | CTD | PMID:35499148 |
Tp53 | Rat | quartz | decreases expression | ISO | RGD:70502 | 6480464 | Quartz results in decreased expression of TP53 mRNA; Quartz results in decreased expression of TP53 more ... | CTD | PMID:27917503|PMID:35499148 |
Tp53 | Rat | quartz | increases mutagenesis | EXP | | 6480464 | Quartz results in increased mutagenesis of TRP53 protein | CTD | PMID:11306444 |
Tp53 | Rat | quercetin | increases acetylation | ISO | RGD:70502 | 6480464 | Quercetin results in increased acetylation of TP53 protein | CTD | PMID:25896587 |
Tp53 | Rat | quercetin | decreases expression | ISO | RGD:11440 | 6480464 | Quercetin results in decreased expression of TRP53 mRNA | CTD | PMID:36819991 |
Tp53 | Rat | quercetin | affects expression | ISO | RGD:70502 | 6480464 | Quercetin affects the expression of TP53 mRNA | CTD | PMID:32530119 |
Tp53 | Rat | quercetin | increases expression | ISO | RGD:11440 | 6480464 | Quercetin results in increased expression of TRP53 mRNA; Quercetin results in increased expression of TRP53 more ... | CTD | PMID:25658812|PMID:25862958 |
Tp53 | Rat | quercetin | increases phosphorylation | ISO | RGD:70502 | 6480464 | Quercetin results in increased phosphorylation of TP53 protein | CTD | PMID:22983795 |
Tp53 | Rat | quercetin | multiple interactions | EXP | | 6480464 | [1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000) co-treated with Quercetin] results in increased expression of TP53 protein; Acetylcysteine inhibits more ... | CTD | PMID:16647178|PMID:23529952|PMID:23907460|PMID:24316378|PMID:24902966|PMID:26944603|PMID:27525270|PMID:33439051|PMID:35337893|PMID:37098359|PMID:38387710 |
Tp53 | Rat | quercetin | decreases expression | ISO | RGD:70502 | 6480464 | Quercetin results in decreased expression of TP53 mRNA; Quercetin results in decreased expression of TP53 more ... | CTD | PMID:16720314|PMID:16948901|PMID:23727915|PMID:24849437 |
Tp53 | Rat | quercetin | multiple interactions | ISO | RGD:70502 | 6480464 | [Cisplatin co-treated with Quercetin] results in decreased expression of TP53 mRNA; [Quercetin analog co-treated with more ... | CTD | PMID:15177039|PMID:15735102|PMID:15795422|PMID:18323654|PMID:19424582|PMID:20577783|PMID:22983795|PMID:23918355|PMID:25078064|PMID:25108166|PMID:25896587|PMID:27514524|PMID:32329368|PMID:32530119 |
Tp53 | Rat | quercetin | affects expression | EXP | | 6480464 | Quercetin affects the expression of TP53 protein | CTD | PMID:22000973 |
Tp53 | Rat | quercetin | multiple interactions | ISO | RGD:11440 | 6480464 | [Curcumin co-treated with Quercetin] inhibits the reaction [Benzo(a)pyrene results in decreased acetylation of TRP53 protein]; more ... | CTD | PMID:18813348|PMID:28681665|PMID:34726822 |
Tp53 | Rat | quercetin | affects localization | ISO | RGD:11440 | 6480464 | Quercetin affects the localization of TRP53 protein | CTD | PMID:18813348 |
Tp53 | Rat | quercetin | increases expression | EXP | | 6480464 | Quercetin results in increased expression of TP53 mRNA | CTD | PMID:18095365 |
Tp53 | Rat | quercetin | increases expression | ISO | RGD:70502 | 6480464 | Quercetin analog results in increased expression of TP53 mRNA; Quercetin analog results in increased expression more ... | CTD | PMID:14715546|PMID:17973296|PMID:19293639|PMID:19623560|PMID:20803121|PMID:21632981|PMID:21933852|PMID:25289772|PMID:25896587|PMID:26311153|PMID:26341291 |
Tp53 | Rat | quercetin 3-O-beta-D-glucofuranoside | multiple interactions | EXP | | 6480464 | isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] | CTD | PMID:30817903 |
Tp53 | Rat | quercetin 3-O-beta-D-glucopyranoside | multiple interactions | EXP | | 6480464 | isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA] | CTD | PMID:30817903 |
Tp53 | Rat | quinacrine | increases activity | ISO | RGD:70502 | 6480464 | Quinacrine results in increased activity of TP53 protein | CTD | PMID:12082016 |
Tp53 | Rat | quinacrine | affects activity | ISO | RGD:70502 | 6480464 | Quinacrine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | quinacrine | multiple interactions | ISO | RGD:70502 | 6480464 | Quinacrine results in increased stability of and results in increased activity of TP53 protein | CTD | PMID:16177561 |
Tp53 | Rat | quinalphos | affects activity | ISO | RGD:70502 | 6480464 | quinalphos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | quinidine | decreases expression | EXP | | 6480464 | Quinidine results in decreased expression of TP53 mRNA | CTD | PMID:17522070 |
Tp53 | Rat | quinoline | increases activity | ISO | RGD:70502 | 6480464 | quinoline analog results in increased activity of TP53 protein | CTD | PMID:12082016 |
Tp53 | Rat | quinoline | increases expression | ISO | RGD:70502 | 6480464 | [quinoline analog results in increased expression of TP53 protein] which results in increased expression of more ... | CTD | PMID:18645022 |
Tp53 | Rat | quizartinib | decreases expression | ISO | RGD:70502 | 6480464 | quizartinib results in decreased expression of TP53 protein | CTD | PMID:34665271 |
Tp53 | Rat | quizartinib | multiple interactions | ISO | RGD:70502 | 6480464 | RGFP966 promotes the reaction [quizartinib results in decreased expression of TP53 protein]; romidepsin promotes the more ... | CTD | PMID:34665271 |
Tp53 | Rat | raloxifene | increases expression | ISO | RGD:70502 | 6480464 | Raloxifene Hydrochloride results in increased expression of TP53 mRNA | CTD | PMID:29705353 |
Tp53 | Rat | raloxifene | multiple interactions | ISO | RGD:70502 | 6480464 | [Raloxifene Hydrochloride co-treated with Resveratrol] results in increased expression of TP53 mRNA | CTD | PMID:29705353 |
Tp53 | Rat | razoxane | affects activity | ISO | RGD:70502 | 6480464 | Razoxane affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Reactive blue 2 | increases degradation | ISO | RGD:70502 | 6480464 | Cibacron Blue F 3GA results in increased degradation of TP53 protein | CTD | PMID:14634213 |
Tp53 | Rat | reactive oxygen species | affects localization | ISO | RGD:70502 | 6480464 | Reactive Oxygen Species affects the localization of TP53 protein | CTD | PMID:26884717 |
Tp53 | Rat | reactive oxygen species | increases expression | ISO | RGD:70502 | 6480464 | Reactive Oxygen Species results in increased expression of TP53 protein | CTD | PMID:10951577|PMID:27634759 |
Tp53 | Rat | reactive oxygen species | multiple interactions | ISO | RGD:70502 | 6480464 | [[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which more ... | CTD | PMID:15059885|PMID:15880691|PMID:17136320|PMID:21042727|PMID:22886373|PMID:26884717|PMID:27634759|PMID:34822033 |
Tp53 | Rat | reactive oxygen species | increases phosphorylation | ISO | RGD:11440 | 6480464 | Reactive Oxygen Species results in increased phosphorylation of TRP53 protein | CTD | PMID:16412576 |
Tp53 | Rat | reactive oxygen species | multiple interactions | ISO | RGD:11440 | 6480464 | [pifithrin results in decreased activity of TRP53 protein] inhibits the reaction [zearalenol affects the abundance more ... | CTD | PMID:20955365|PMID:23376438|PMID:26884717 |
Tp53 | Rat | reactive oxygen species | increases abundance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased abundance of Reactive Oxygen Species | CTD | PMID:15059885 |
Tp53 | Rat | reactive oxygen species | affects localization | ISO | RGD:11440 | 6480464 | Reactive Oxygen Species affects the localization of TRP53 protein | CTD | PMID:26884717 |
Tp53 | Rat | resveratrol | multiple interactions | ISO | RGD:70502 | 6480464 | 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one promotes the reaction [TP53 protein results in increased susceptibility to Resveratrol]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the more ... | CTD | PMID:11889192|PMID:11895857|PMID:12131363|PMID:15542774|PMID:16518869|PMID:16790523|PMID:16814113|PMID:16928824|PMID:17534123|PMID:17868649|PMID:17959154|PMID:18222423|PMID:18446786|PMID:18497562|PMID:18681908|PMID:19559722|PMID:19631782|PMID:19810103|PMID:19846903|PMID:20068143|PMID:21743969|PMID:23088850|PMID:23152798|PMID:23217256|PMID:23257246|PMID:23495037|PMID:23651583|PMID:23859249|PMID:23881456|PMID:24218232|PMID:24239893|PMID:24603648|PMID:24933654|PMID:25533949|PMID:25895606|PMID:25991017|PMID:26188290|PMID:26969377|PMID:27049278|PMID:29242151|PMID:29705353|PMID:34216621 |
Tp53 | Rat | resveratrol | decreases activity | ISO | RGD:70502 | 6480464 | resveratrol results in decreased activity of TP53 protein | CTD | PMID:22252971|PMID:25956474 |
Tp53 | Rat | resveratrol | decreases expression | EXP | | 6480464 | Resveratrol results in decreased expression of TP53 mRNA; Resveratrol results in decreased expression of TP53 more ... | CTD | PMID:23792339|PMID:33775663 |
Tp53 | Rat | resveratrol | affects localization | ISO | RGD:70502 | 6480464 | resveratrol affects the localization of TP53 protein | CTD | PMID:18446786|PMID:24587049 |
Tp53 | Rat | resveratrol | increases expression | ISO | RGD:11440 | 6480464 | resveratrol results in increased expression of TRP53 protein | CTD | PMID:15122319|PMID:25505154 |
Tp53 | Rat | resveratrol | increases phosphorylation | ISO | RGD:70502 | 6480464 | resveratrol results in increased phosphorylation of TP53 protein | CTD | PMID:16790523|PMID:16814113|PMID:16928824|PMID:18222423|PMID:23495037|PMID:23651583|PMID:24933654|PMID:25311616|PMID:29242151 |
Tp53 | Rat | resveratrol | increases acetylation | ISO | RGD:11440 | 6480464 | resveratrol results in increased acetylation of TP53 protein | CTD | PMID:25533949 |
Tp53 | Rat | resveratrol | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to resveratrol | CTD | PMID:11889192|PMID:16518869|PMID:23152798 |
Tp53 | Rat | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of TP53 protein; resveratrol results in increased expression of TP53 more ... | CTD | PMID:20797428|PMID:20972827 |
Tp53 | Rat | resveratrol | increases expression | ISO | RGD:70502 | 6480464 | [Resveratrol results in increased expression of TP53 protein] which results in increased expression of GDF15 more ... | CTD | PMID:11889192|PMID:11895857|PMID:15149879|PMID:15993843|PMID:16091005|PMID:16209266|PMID:16759640|PMID:17007014|PMID:17050787|PMID:17088997|PMID:17261084|PMID:18089832|PMID:18347188|PMID:19800779|PMID:19846903|PMID:21743969|PMID:22029423|PMID:23152798|PMID:25242450|PMID:25436977|PMID:25776512|PMID:25895606|PMID:26341291|PMID:26911335|PMID:26969377|PMID:26970359|PMID:29242151|PMID:29274324|PMID:29705353 |
Tp53 | Rat | resveratrol | increases activity | ISO | RGD:70502 | 6480464 | Resveratrol results in increased activity of TP53 protein | CTD | PMID:20504360|PMID:21740780 |
Tp53 | Rat | resveratrol | increases activity | ISO | RGD:11440 | 6480464 | resveratrol results in increased activity of TRP53 protein | CTD | PMID:12687016 |
Tp53 | Rat | resveratrol | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 affects the susceptibility to resveratrol | CTD | PMID:18497562|PMID:19846903 |
Tp53 | Rat | resveratrol | affects expression | ISO | RGD:70502 | 6480464 | resveratrol affects the expression of TP53 protein | CTD | PMID:11522280 |
Tp53 | Rat | resveratrol | decreases expression | ISO | RGD:11440 | 6480464 | resveratrol results in decreased expression of TRP53 protein | CTD | PMID:16369916 |
Tp53 | Rat | resveratrol | affects expression | ISO | RGD:11440 | 6480464 | resveratrol affects the expression of TRP53 mRNA | CTD | PMID:16369916 |
Tp53 | Rat | resveratrol | increases phosphorylation | EXP | | 6480464 | resveratrol results in increased phosphorylation of TP53 protein | CTD | PMID:17984113 |
Tp53 | Rat | resveratrol | multiple interactions | ISO | RGD:11440 | 6480464 | 1-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-2,7,9a-benzo(cd)azulen-6-one inhibits the reaction [Resveratrol results in increased acetylation of TP53 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the more ... | CTD | PMID:11245472|PMID:11933078|PMID:17581637|PMID:19819963|PMID:21593185|PMID:22763982|PMID:24040102|PMID:24885036|PMID:25440059|PMID:25533949|PMID:25665036|PMID:25956474 |
Tp53 | Rat | resveratrol | multiple interactions | EXP | | 6480464 | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Resveratrol results in increased phosphorylation of TP53 protein]; Resveratrol inhibits the more ... | CTD | PMID:17147953|PMID:17984113|PMID:20797428|PMID:23792339|PMID:24492640|PMID:24894866|PMID:34968465|PMID:36493885 |
Tp53 | Rat | resveratrol | decreases acetylation | ISO | RGD:11440 | 6480464 | resveratrol results in decreased acetylation of TRP53 protein | CTD | PMID:17581637|PMID:23129026|PMID:24040102 |
Tp53 | Rat | RGFP966 | multiple interactions | ISO | RGD:70502 | 6480464 | RGFP966 promotes the reaction [quizartinib results in decreased expression of TP53 protein] | CTD | PMID:34665271 |
Tp53 | Rat | ribavirin | increases expression | ISO | RGD:70502 | 6480464 | Ribavirin results in increased expression of TP53 protein | CTD | PMID:32112805 |
Tp53 | Rat | ribavirin | affects activity | ISO | RGD:70502 | 6480464 | Ribavirin affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | ribavirin | increases expression | ISO | RGD:11440 | 6480464 | Ribavirin results in increased expression of TRP53 protein | CTD | PMID:33577917 |
Tp53 | Rat | riboflavin | increases expression | ISO | RGD:70502 | 6480464 | Riboflavin results in increased expression of TP53 protein | CTD | PMID:12654180 |
Tp53 | Rat | riddelliine | increases expression | EXP | | 6480464 | riddelliine results in increased expression of TP53 protein | CTD | PMID:12460743|PMID:20737008 |
Tp53 | Rat | riddelliine | increases mutagenesis | ISO | RGD:11440 | 6480464 | riddelliine results in increased mutagenesis of TRP53 gene | CTD | PMID:13678655|PMID:20737008 |
Tp53 | Rat | ritonavir | multiple interactions | ISO | RGD:70502 | 6480464 | FTI 277 inhibits the reaction [Ritonavir results in increased expression of TP53 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin more ... | CTD | PMID:20884875 |
Tp53 | Rat | ritonavir | increases expression | ISO | RGD:70502 | 6480464 | Ritonavir results in increased expression of TP53 protein | CTD | PMID:19386116|PMID:20884875 |
Tp53 | Rat | rivastigmine | affects activity | ISO | RGD:70502 | 6480464 | Rivastigmine metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | romidepsin | multiple interactions | ISO | RGD:70502 | 6480464 | romidepsin promotes the reaction [quizartinib results in decreased expression of TP53 protein] | CTD | PMID:34665271 |
Tp53 | Rat | Roridin A | increases expression | ISO | RGD:11440 | 6480464 | roridin A results in increased expression of TRP53 mRNA | CTD | PMID:17483119 |
Tp53 | Rat | rotenone | affects localization | ISO | RGD:70502 | 6480464 | Rotenone affects the localization of TP53 protein | CTD | PMID:21223980 |
Tp53 | Rat | rotenone | decreases expression | ISO | RGD:70502 | 6480464 | Rotenone results in decreased expression of TP53 mRNA | CTD | PMID:37210002 |
Tp53 | Rat | rotenone | affects localization | ISO | RGD:11440 | 6480464 | Rotenone affects the localization of TRP53 protein | CTD | PMID:23899557 |
Tp53 | Rat | rotenone | multiple interactions | EXP | | 6480464 | Catechin inhibits the reaction [Rotenone results in increased expression of TP53 mRNA]; GAPDH mutant form more ... | CTD | PMID:25725130|PMID:30222980|PMID:35337893 |
Tp53 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of TP53 mRNA; Rotenone results in increased expression of TP53 more ... | CTD | PMID:25725130|PMID:28374803|PMID:30222980|PMID:35187747|PMID:35337893 |
Tp53 | Rat | rotenone | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein results in increased susceptibility to Rotenone | CTD | PMID:26031332 |
Tp53 | Rat | rotenone | increases expression | ISO | RGD:70502 | 6480464 | Rotenone results in increased expression of TP53 mRNA; Rotenone results in increased expression of TP53 more ... | CTD | PMID:18191903|PMID:23963993|PMID:25991017|PMID:29886133 |
Tp53 | Rat | rotenone | multiple interactions | ISO | RGD:11440 | 6480464 | PK 11195 inhibits the reaction [Rotenone affects the localization of TRP53 protein]; TRP53 affects the more ... | CTD | PMID:21893155|PMID:23899557|PMID:26031332 |
Tp53 | Rat | rotenone | increases localization | ISO | RGD:11440 | 6480464 | Rotenone results in increased localization of TRP53 protein | CTD | PMID:21893155 |
Tp53 | Rat | rotenone | increases expression | ISO | RGD:11440 | 6480464 | Rotenone results in increased expression of TP53 protein; Rotenone results in increased expression of TRP53 more ... | CTD | PMID:10630619|PMID:26031332|PMID:35919817 |
Tp53 | Rat | rotenone | multiple interactions | ISO | RGD:70502 | 6480464 | [PSME4 protein affects the susceptibility to Rotenone] which results in decreased expression of TP53 mRNA; more ... | CTD | PMID:21223980|PMID:25991017|PMID:28703385|PMID:29886133|PMID:32368861 |
Tp53 | Rat | royal jelly | multiple interactions | ISO | RGD:11440 | 6480464 | royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] | CTD | PMID:30896085 |
Tp53 | Rat | rubitecan | multiple interactions | ISO | RGD:70502 | 6480464 | Phosphatidylcholines inhibits the reaction [rubitecan results in increased expression of TP53 protein] | CTD | PMID:21695227 |
Tp53 | Rat | rubitecan | increases expression | ISO | RGD:70502 | 6480464 | rubitecan results in increased expression of TP53 protein | CTD | PMID:21695227 |
Tp53 | Rat | ruthenium atom | increases expression | ISO | RGD:70502 | 6480464 | Ruthenium results in increased expression of TP53 protein | CTD | PMID:17210701 |
Tp53 | Rat | ruthenium atom | multiple interactions | ISO | RGD:70502 | 6480464 | [Ruthenium binds to Phloretin] which results in increased expression of TP53 protein | CTD | PMID:34896434 |
Tp53 | Rat | ruthenium atom | multiple interactions | EXP | | 6480464 | [Ruthenium binds to Phloretin] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 protein] | CTD | PMID:34896434 |
Tp53 | Rat | rutin | multiple interactions | EXP | | 6480464 | Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of TP53 mRNA] | CTD | PMID:27239252 |
Tp53 | Rat | rutin | multiple interactions | ISO | RGD:70502 | 6480464 | Rutin inhibits the reaction [Cisplatin results in increased expression of TP53 protein] | CTD | PMID:29962303 |
Tp53 | Rat | rutin | multiple interactions | ISO | RGD:11440 | 6480464 | Rutin inhibits the reaction [Carbon Tetrachloride results in increased expression of TRP53 protein] | CTD | PMID:29522708 |
Tp53 | Rat | ruxolitinib | multiple interactions | ISO | RGD:70502 | 6480464 | [ruxolitinib co-treated with Arsenic Trioxide] results in increased expression of TP53 mRNA; [ruxolitinib co-treated with more ... | CTD | PMID:30012499 |
Tp53 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | increases expression | ISO | RGD:70502 | 6480464 | S-(1,2-dichlorovinyl)cysteine results in increased expression of TP53 protein | CTD | PMID:15967204 |
Tp53 | Rat | S-(2-Chloroethyl)glutathione | increases mutagenesis | ISO | RGD:70502 | 6480464 | S-(2-chloroethyl)glutathione results in increased mutagenesis of TP53 gene | CTD | PMID:14715658 |
Tp53 | Rat | S-(2-Chloroethyl)glutathione | multiple interactions | ISO | RGD:70502 | 6480464 | [S-(2-chloroethyl)glutathione results in increased mutagenesis of TP53 gene] which results in decreased activity of TP53 more ... | CTD | PMID:14715658 |
Tp53 | Rat | S-allylcysteine | multiple interactions | ISO | RGD:70502 | 6480464 | SB 203580 inhibits the reaction [S-allylcysteine results in increased phosphorylation of TP53 protein] | CTD | PMID:31067004 |
Tp53 | Rat | S-allylcysteine | increases phosphorylation | ISO | RGD:70502 | 6480464 | S-allylcysteine results in increased phosphorylation of TP53 protein | CTD | PMID:31067004 |
Tp53 | Rat | S-allylcysteine | multiple interactions | ISO | RGD:11440 | 6480464 | [Diethylnitrosamine co-treated with S-allylcysteine] results in increased phosphorylation of TRP53 protein | CTD | PMID:31067004 |
Tp53 | Rat | S-butyl-DL-homocysteine (S,R)-sulfoximine | multiple interactions | ISO | RGD:70502 | 6480464 | [Buthionine Sulfoximine results in decreased abundance of Glutathione] inhibits the reaction [Benzo(a)pyrene results in increased more ... | CTD | PMID:12807757 |
Tp53 | Rat | S-butyl-DL-homocysteine (S,R)-sulfoximine | multiple interactions | EXP | | 6480464 | [cyanoginosin LR co-treated with Buthionine Sulfoximine] results in increased expression of TP53 protein | CTD | PMID:25410294 |
Tp53 | Rat | S-nitroso-L-cysteine | multiple interactions | ISO | RGD:70502 | 6480464 | S-nitrosocysteine inhibits the reaction [SIRT1 protein results in decreased acetylation of TP53 protein] | CTD | PMID:24451382 |
Tp53 | Rat | S-nitroso-N-acetyl-D-penicillamine | multiple interactions | ISO | RGD:11440 | 6480464 | [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] which results in increased expression of TRP53 more ... | CTD | PMID:7673702 |
Tp53 | Rat | S-nitroso-N-acetyl-D-penicillamine | multiple interactions | ISO | RGD:70502 | 6480464 | S-Nitroso-N-Acetylpenicillamine promotes the reaction [FGF2 protein results in increased expression of TP53 protein] | CTD | PMID:16351512 |
Tp53 | Rat | S-nitrosoglutathione | multiple interactions | EXP | | 6480464 | [S-Nitrosoglutathione results in increased abundance of Nitric Oxide] which results in increased expression of TP53 more ... | CTD | PMID:8982730 |
Tp53 | Rat | S-nitrosoglutathione | multiple interactions | ISO | RGD:70502 | 6480464 | [S-Nitrosoglutathione results in increased nitrosation of PRKN protein] inhibits the reaction [PRKN protein binds to more ... | CTD | PMID:23985028 |
Tp53 | Rat | Salinomycin | decreases expression | ISO | RGD:70502 | 6480464 | salinomycin results in decreased expression of TP53 mRNA | CTD | PMID:34806536 |
Tp53 | Rat | salvianolic acid B | decreases acetylation | ISO | RGD:70502 | 6480464 | salvianolic acid B results in decreased acetylation of TP53 protein | CTD | PMID:24769256 |
Tp53 | Rat | salvianolic acid B | multiple interactions | EXP | | 6480464 | salvianolic acid B inhibits the reaction [Ethanol results in increased acetylation of TP53 protein] | CTD | PMID:24769256 |
Tp53 | Rat | sappanchalcone | increases expression | ISO | RGD:70502 | 6480464 | sappanchalcone results in increased expression of TP53 protein | CTD | PMID:21963806 |
Tp53 | Rat | sappanchalcone | multiple interactions | ISO | RGD:70502 | 6480464 | sappanchalcone results in increased expression of and results in increased phosphorylation of TP53 protein | CTD | PMID:32590072 |
Tp53 | Rat | sapropterin | multiple interactions | ISO | RGD:70502 | 6480464 | sapropterin inhibits the reaction [Methotrexate results in increased expression of TP53 protein] | CTD | PMID:22183962 |
Tp53 | Rat | SB 203580 | multiple interactions | EXP | | 6480464 | SB 203580 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein] | CTD | PMID:16005925 |
Tp53 | Rat | SB 203580 | multiple interactions | ISO | RGD:11440 | 6480464 | SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of and results in increased more ... | CTD | PMID:15976193|PMID:27270636 |
Tp53 | Rat | SB 203580 | multiple interactions | ISO | RGD:70502 | 6480464 | SB 203580 inhibits the reaction [[Cisplatin co-treated with fisetin] results in increased phosphorylation of TP53 more ... | CTD | PMID:15734884|PMID:17136320|PMID:19020741|PMID:19082730|PMID:20191265|PMID:21216935|PMID:31067004|PMID:38431053 |
Tp53 | Rat | selenium atom | multiple interactions | ISO | RGD:70502 | 6480464 | [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression more ... | CTD | PMID:19244175|PMID:27920530 |
Tp53 | Rat | selenium atom | decreases expression | ISO | RGD:70502 | 6480464 | Selenium results in decreased expression of TP53 protein | CTD | PMID:17523932 |
Tp53 | Rat | selenium atom | multiple interactions | EXP | | 6480464 | [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 more ... | CTD | PMID:16600092|PMID:21628957|PMID:37987225 |
Tp53 | Rat | selenium atom | increases expression | ISO | RGD:70502 | 6480464 | Selenium results in increased expression of TP53 mRNA | CTD | PMID:19244175 |
Tp53 | Rat | selenomethionine | multiple interactions | ISO | RGD:70502 | 6480464 | AR protein promotes the reaction [Selenomethionine results in increased expression of TP53 mRNA]; Selenomethionine inhibits more ... | CTD | PMID:17205524|PMID:21515331 |
Tp53 | Rat | selenomethionine | decreases expression | ISO | RGD:11440 | 6480464 | Selenomethionine results in decreased expression of TRP53 protein | CTD | PMID:20659492 |
Tp53 | Rat | selenomethionine | multiple interactions | ISO | RGD:11440 | 6480464 | Diethylhexyl Phthalate inhibits the reaction [Selenomethionine results in decreased expression of TRP53 protein]; Selenomethionine inhibits more ... | CTD | PMID:20659492 |
Tp53 | Rat | selenomethionine | increases expression | ISO | RGD:70502 | 6480464 | Selenomethionine results in increased expression of TP53 mRNA | CTD | PMID:17205524 |
Tp53 | Rat | selenomethionine | decreases activity | ISO | RGD:70502 | 6480464 | Selenomethionine results in decreased activity of TP53 protein | CTD | PMID:17100737 |
Tp53 | Rat | selinexor | increases expression | ISO | RGD:70502 | 6480464 | selinexor results in increased expression of TP53 protein | CTD | PMID:37899423 |
Tp53 | Rat | selinexor | multiple interactions | ISO | RGD:70502 | 6480464 | [INCB057643 co-treated with selinexor] results in increased expression of TP53 protein | CTD | PMID:37899423 |
Tp53 | Rat | senecionine | increases expression | ISO | RGD:11440 | 6480464 | senecionine results in increased expression of TRP53 mRNA; senecionine results in increased expression of TRP53 more ... | CTD | PMID:35357534 |
Tp53 | Rat | senecionine | increases expression | ISO | RGD:70502 | 6480464 | senecionine results in increased expression of TP53 mRNA | CTD | PMID:35357534 |
Tp53 | Rat | serpentine asbestos | decreases expression | EXP | | 6480464 | Asbestos, Serpentine results in decreased expression of TP53 mRNA; Asbestos, Serpentine results in decreased expression more ... | CTD | PMID:32755622 |
Tp53 | Rat | serpentine asbestos | increases expression | EXP | | 6480464 | Asbestos, Serpentine results in increased expression of TP53 protein | CTD | PMID:9115760 |
Tp53 | Rat | serpentine asbestos | increases expression | ISO | RGD:70502 | 6480464 | Asbestos, Serpentine results in increased expression of TP53 protein | CTD | PMID:12676607 |
Tp53 | Rat | serpentine asbestos | multiple interactions | ISO | RGD:70502 | 6480464 | wortmannin inhibits the reaction [Asbestos, Serpentine results in increased expression of TP53 protein]; wortmannin inhibits more ... | CTD | PMID:12676607 |
Tp53 | Rat | serpentine asbestos | increases phosphorylation | ISO | RGD:70502 | 6480464 | Asbestos, Serpentine results in increased phosphorylation of TP53 protein | CTD | PMID:12676607 |
Tp53 | Rat | sevoflurane | increases expression | ISO | RGD:70502 | 6480464 | sevoflurane results in increased expression of TP53 mRNA | CTD | PMID:19572936 |
Tp53 | Rat | Shikonin | increases expression | ISO | RGD:70502 | 6480464 | shikonin results in increased expression of TP53 protein | CTD | PMID:28684144 |
Tp53 | Rat | sildenafil citrate | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein inhibits the reaction [Sildenafil Citrate results in increased susceptibility to Doxorubicin] | CTD | PMID:20155316 |
Tp53 | Rat | sildenafil citrate | increases expression | ISO | RGD:11440 | 6480464 | Sildenafil Citrate results in increased expression of TP53 protein | CTD | PMID:38059649 |
Tp53 | Rat | silibinin | increases phosphorylation | ISO | RGD:70502 | 6480464 | Silybin results in increased phosphorylation of TP53 protein | CTD | PMID:16777994 |
Tp53 | Rat | silibinin | affects localization | ISO | RGD:70502 | 6480464 | Silybin affects the localization of TP53 protein | CTD | PMID:16777994 |
Tp53 | Rat | silibinin | increases expression | ISO | RGD:70502 | 6480464 | Silybin results in increased expression of TP53 protein | CTD | PMID:16777994 |
Tp53 | Rat | silibinin | multiple interactions | ISO | RGD:70502 | 6480464 | Caffeine inhibits the reaction [Silybin results in increased phosphorylation of TP53 protein]; pifithrin inhibits the more ... | CTD | PMID:16777994|PMID:19834285 |
Tp53 | Rat | silicon dioxide | multiple interactions | ISO | RGD:70502 | 6480464 | [BMI1 protein co-treated with Silicon Dioxide] results in increased expression of TP53 protein; Ascorbic Acid more ... | CTD | PMID:22245848|PMID:22931364|PMID:31082419|PMID:35288261 |
Tp53 | Rat | silicon dioxide | decreases expression | ISO | RGD:70502 | 6480464 | Silicon Dioxide results in decreased expression of TP53 mRNA; Silicon Dioxide results in decreased expression more ... | CTD | PMID:25351596|PMID:35288261 |
Tp53 | Rat | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of TP53 protein | CTD | PMID:26865670 |
Tp53 | Rat | silicon dioxide | increases phosphorylation | ISO | RGD:11440 | 6480464 | Silicon Dioxide results in increased phosphorylation of TRP53 protein | CTD | PMID:27616297 |
Tp53 | Rat | silicon dioxide | multiple interactions | EXP | | 6480464 | ZC3H12A affects the reaction [Silicon Dioxide results in increased expression of TP53 protein] | CTD | PMID:26865670 |
Tp53 | Rat | silicon dioxide | increases expression | ISO | RGD:70502 | 6480464 | Silicon Dioxide results in increased expression of TP53 mRNA; Silicon Dioxide results in increased expression more ... | CTD | PMID:20060462|PMID:21766316|PMID:22245848|PMID:22931364 |
Tp53 | Rat | silmitasertib | decreases expression | ISO | RGD:70502 | 6480464 | silmitasertib results in decreased expression of TP53 protein | CTD | PMID:25798061 |
Tp53 | Rat | silmitasertib | affects expression | ISO | RGD:70502 | 6480464 | silmitasertib affects the expression of TP53 protein | CTD | PMID:25798061 |
Tp53 | Rat | silver atom | increases expression | ISO | RGD:70502 | 6480464 | Silver results in increased expression of TP53 protein | CTD | PMID:22546375 |
Tp53 | Rat | silver atom | increases expression | ISO | RGD:11440 | 6480464 | Silver results in increased expression of TRP53 mRNA; Silver results in increased expression of TRP53 more ... | CTD | PMID:29665414 |
Tp53 | Rat | silver atom | multiple interactions | ISO | RGD:70502 | 6480464 | [Silver co-treated with Povidone] affects the phosphorylation of TP53 protein; [Silver co-treated with Povidone] results more ... | CTD | PMID:22546375|PMID:27387714 |
Tp53 | Rat | silver(0) | increases expression | ISO | RGD:70502 | 6480464 | Silver results in increased expression of TP53 protein | CTD | PMID:22546375 |
Tp53 | Rat | silver(0) | increases expression | ISO | RGD:11440 | 6480464 | Silver results in increased expression of TRP53 mRNA; Silver results in increased expression of TRP53 more ... | CTD | PMID:29665414 |
Tp53 | Rat | silver(0) | multiple interactions | ISO | RGD:70502 | 6480464 | [Silver co-treated with Povidone] affects the phosphorylation of TP53 protein; [Silver co-treated with Povidone] results more ... | CTD | PMID:22546375|PMID:27387714 |
Tp53 | Rat | silver(1+) nitrate | decreases expression | ISO | RGD:70502 | 6480464 | Silver Nitrate analog results in decreased expression of TP53 mRNA | CTD | PMID:22831968 |
Tp53 | Rat | simvastatin | multiple interactions | ISO | RGD:70502 | 6480464 | pifithrin inhibits the reaction [Simvastatin results in increased expression of TP53 protein]; Simvastatin promotes the more ... | CTD | PMID:15625077|PMID:20045437|PMID:21199873 |
Tp53 | Rat | simvastatin | increases expression | ISO | RGD:70502 | 6480464 | Simvastatin results in increased expression of TP53 mRNA; Simvastatin results in increased expression of TP53 more ... | CTD | PMID:20045437|PMID:21199873 |
Tp53 | Rat | simvastatin | increases expression | EXP | | 6480464 | Simvastatin results in increased expression of TP53 protein | CTD | PMID:18804536 |
Tp53 | Rat | simvastatin | increases phosphorylation | ISO | RGD:70502 | 6480464 | Simvastatin results in increased phosphorylation of TP53 protein | CTD | PMID:20045437 |
Tp53 | Rat | sinapic acid | multiple interactions | EXP | | 6480464 | sinapinic acid inhibits the reaction [Vancomycin results in increased expression of TP53 mRNA] | CTD | PMID:39059777 |
Tp53 | Rat | sirolimus | multiple interactions | ISO | RGD:70502 | 6480464 | [Sirolimus results in decreased activity of MTOR protein] which results in decreased phosphorylation of TP53 more ... | CTD | PMID:11602639|PMID:19560264|PMID:30555576 |
Tp53 | Rat | sirolimus | multiple interactions | ISO | RGD:11440 | 6480464 | Sirolimus inhibits the reaction [arsenite results in increased expression of and results in increased phosphorylation more ... | CTD | PMID:23396362 |
Tp53 | Rat | sirolimus | increases expression | EXP | | 6480464 | Sirolimus results in increased expression of TP53 mRNA | CTD | PMID:24971338 |
Tp53 | Rat | sirolimus | decreases phosphorylation | ISO | RGD:70502 | 6480464 | Sirolimus results in decreased phosphorylation of TP53 protein | CTD | PMID:11602639 |
Tp53 | Rat | sirtinol | multiple interactions | ISO | RGD:70502 | 6480464 | [sirtinol results in decreased activity of SIRT1 protein] promotes the reaction [Hydrogen Peroxide results in more ... | CTD | PMID:18298901|PMID:18681908|PMID:23881456 |
Tp53 | Rat | sirtinol | multiple interactions | ISO | RGD:11440 | 6480464 | sirtinol inhibits the reaction [resveratrol inhibits the reaction [Doxorubicin results in increased expression of TRP53 more ... | CTD | PMID:25665036 |
Tp53 | Rat | skatole | multiple interactions | ISO | RGD:70502 | 6480464 | Skatole results in increased phosphorylation of and affects the localization of TP53 protein | CTD | PMID:19700606 |
Tp53 | Rat | sodium arsenite | increases methylation | ISO | RGD:11440 | 6480464 | sodium arsenite results in increased methylation of TP53 gene | CTD | PMID:32068019 |
Tp53 | Rat | sodium arsenite | multiple interactions | EXP | | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TP53 more ... | CTD | PMID:30066062|PMID:31163222|PMID:31542844|PMID:32402895|PMID:36437433 |
Tp53 | Rat | sodium arsenite | increases phosphorylation | EXP | | 6480464 | sodium arsenite results in increased phosphorylation of TP53 protein | CTD | PMID:31163222 |
Tp53 | Rat | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of TP53 mRNA; sodium arsenite results in decreased expression more ... | CTD | PMID:28785074|PMID:36437433 |
Tp53 | Rat | sodium arsenite | affects localization | ISO | RGD:11440 | 6480464 | sodium arsenite affects the localization of TRP53 protein | CTD | PMID:27723467 |
Tp53 | Rat | sodium arsenite | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to sodium arsenite | CTD | PMID:20477944 |
Tp53 | Rat | sodium arsenite | decreases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in decreased susceptibility to sodium arsenite | CTD | PMID:16166651 |
Tp53 | Rat | sodium arsenite | increases stability | ISO | RGD:11440 | 6480464 | sodium arsenite results in increased stability of TRP53 protein | CTD | PMID:18996350 |
Tp53 | Rat | sodium arsenite | increases phosphorylation | ISO | RGD:11440 | 6480464 | sodium arsenite results in increased phosphorylation of TRP53 protein | CTD | PMID:16166651|PMID:18996350|PMID:23890198 |
Tp53 | Rat | sodium arsenite | decreases expression | ISO | RGD:11440 | 6480464 | sodium arsenite results in decreased expression of TRP53 mRNA | CTD | PMID:16014739 |
Tp53 | Rat | sodium arsenite | multiple interactions | ISO | RGD:11440 | 6480464 | [dibenzo(a,l)pyrene co-treated with sodium arsenite] results in increased expression of TRP53 protein; [sodium arsenite results more ... | CTD | PMID:16166651|PMID:18996350|PMID:20353797|PMID:20477944|PMID:22003191|PMID:25787150|PMID:27723467|PMID:29944914|PMID:35714946 |
Tp53 | Rat | sodium arsenite | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein mutant form results in decreased susceptibility to sodium arsenite; TP53 protein results in more ... | CTD | PMID:16614167|PMID:21454520 |
Tp53 | Rat | sodium arsenite | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to sodium arsenite; TP53 protein mutant form affects the susceptibility more ... | CTD | PMID:16338954|PMID:17567589|PMID:20000476|PMID:22331493 |
Tp53 | Rat | sodium arsenite | increases ribosylation | ISO | RGD:70502 | 6480464 | sodium arsenite results in increased ribosylation of TP53 protein | CTD | PMID:20036271 |
Tp53 | Rat | sodium arsenite | increases phosphorylation | ISO | RGD:70502 | 6480464 | sodium arsenite results in increased phosphorylation of TP53 protein | CTD | PMID:16614167|PMID:20375080|PMID:22706169|PMID:26091798|PMID:28586017|PMID:36958258 |
Tp53 | Rat | sodium arsenite | increases methylation | ISO | RGD:70502 | 6480464 | sodium arsenite results in increased methylation of TP53 promoter | CTD | PMID:22551203 |
Tp53 | Rat | sodium arsenite | increases expression | ISO | RGD:70502 | 6480464 | sodium arsenite results in increased expression of TP53 mRNA; sodium arsenite results in increased expression more ... | CTD | PMID:11507245|PMID:11813266|PMID:15734884|PMID:16338954|PMID:17567589|PMID:19382146|PMID:19931552|PMID:20390378|PMID:22102309|PMID:22706169|PMID:23219847|PMID:23549458|PMID:26091798|PMID:28703385|PMID:31120745|PMID:33256086 |
Tp53 | Rat | sodium arsenite | increases activity | ISO | RGD:70502 | 6480464 | sodium arsenite results in increased activity of TP53 protein | CTD | PMID:17567589|PMID:19931552|PMID:23219847 |
Tp53 | Rat | sodium arsenite | decreases phosphorylation | ISO | RGD:70502 | 6480464 | sodium arsenite results in decreased phosphorylation of TP53 protein | CTD | PMID:22706169|PMID:27287256 |
Tp53 | Rat | sodium arsenite | decreases methylation | ISO | RGD:70502 | 6480464 | sodium arsenite results in decreased methylation of TP53 gene | CTD | PMID:25199682 |
Tp53 | Rat | sodium arsenite | decreases expression | ISO | RGD:70502 | 6480464 | sodium arsenite results in decreased expression of TP53 mRNA; sodium arsenite results in decreased expression more ... | CTD | PMID:12377979|PMID:17567589|PMID:19615344|PMID:21454520|PMID:22199297|PMID:22692362|PMID:22706169|PMID:24068038|PMID:27908234|PMID:38568856 |
Tp53 | Rat | sodium arsenite | affects localization | ISO | RGD:70502 | 6480464 | sodium arsenite affects the localization of TP53 protein | CTD | PMID:19010883|PMID:19931552|PMID:20375080 |
Tp53 | Rat | sodium arsenite | affects expression | ISO | RGD:70502 | 6480464 | sodium arsenite affects the expression of TP53 mRNA | CTD | PMID:23804311 |
Tp53 | Rat | sodium arsenite | multiple interactions | ISO | RGD:70502 | 6480464 | 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [sodium arsenite results in decreased phosphorylation of TP53 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile promotes more ... | CTD | PMID:11507245|PMID:15734884|PMID:16614167|PMID:16966095|PMID:17849503|PMID:19010883|PMID:19082730|PMID:19931552|PMID:20375080|PMID:20390378|PMID:21292642|PMID:21454520|PMID:21696631|PMID:22331493|PMID:22692362|PMID:22706169|PMID:23192986|PMID:26148435|PMID:27287256|PMID:28703385|PMID:28785074|PMID:29319823|PMID:33256086|PMID:34798143|PMID:36087615|PMID:39836092 |
Tp53 | Rat | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of TP53 mRNA; sodium arsenite results in increased expression more ... | CTD | PMID:16797887|PMID:30066062|PMID:31163222 |
Tp53 | Rat | sodium arsenite | increases expression | ISO | RGD:11440 | 6480464 | sodium arsenite results in increased expression of TP53 protein; sodium arsenite results in increased expression more ... | CTD | PMID:16338954|PMID:20353797|PMID:27723467|PMID:29854073|PMID:30278210 |
Tp53 | Rat | sodium azide | multiple interactions | ISO | RGD:70502 | 6480464 | Sodium Azide inhibits the reaction [2-butylamino-2-demethoxy-hypocrellin B results in increased expression of TP53 mRNA] | CTD | PMID:17045927 |
Tp53 | Rat | sodium benzoate | multiple interactions | ISO | RGD:70502 | 6480464 | Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA] | CTD | PMID:16357363 |
Tp53 | Rat | sodium benzoate | increases expression | EXP | | 6480464 | Sodium Benzoate results in increased expression of TP53 protein | CTD | PMID:32911041 |
Tp53 | Rat | sodium chloride | increases expression | ISO | RGD:70502 | 6480464 | Sodium Chloride results in increased expression of TP53 mRNA | CTD | PMID:23634900 |
Tp53 | Rat | sodium chloride | multiple interactions | ISO | RGD:11440 | 6480464 | Sodium Chloride results in increased phosphorylation of and affects the localization of TRP53 protein | CTD | PMID:15975986 |
Tp53 | Rat | sodium chloride | multiple interactions | EXP | | 6480464 | [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein; acetovanillone inhibits the more ... | CTD | PMID:22431579 |
Tp53 | Rat | sodium cholate | multiple interactions | ISO | RGD:11440 | 6480464 | [Cholesterol, Dietary co-treated with Sodium Cholate] results in decreased expression of TRP53 protein; MET gene more ... | CTD | PMID:27394961 |
Tp53 | Rat | sodium chromate | increases expression | ISO | RGD:70502 | 6480464 | sodium chromate(VI) results in increased expression of TP53 protein | CTD | PMID:16283527 |
Tp53 | Rat | sodium chromate | multiple interactions | ISO | RGD:11440 | 6480464 | [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation more ... | CTD | PMID:35643323 |
Tp53 | Rat | sodium dichromate | multiple interactions | ISO | RGD:11440 | 6480464 | CAT protein inhibits the reaction [sodium bichromate results in increased phosphorylation of TRP53 protein]; TRP53 more ... | CTD | PMID:20298709 |
Tp53 | Rat | sodium dichromate | decreases expression | EXP | | 6480464 | sodium bichromate results in decreased expression of TP53 mRNA; sodium bichromate results in decreased expression more ... | CTD | PMID:21437922 |
Tp53 | Rat | sodium dichromate | decreases expression | ISO | RGD:70502 | 6480464 | sodium bichromate results in decreased expression of TP53 mRNA | CTD | PMID:27825931 |
Tp53 | Rat | sodium dichromate | increases phosphorylation | ISO | RGD:70502 | 6480464 | sodium bichromate results in increased phosphorylation of TP53 protein | CTD | PMID:26091798 |
Tp53 | Rat | sodium dichromate | affects response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein affects the susceptibility to sodium bichromate | CTD | PMID:10802220|PMID:11678597 |
Tp53 | Rat | sodium dichromate | increases expression | ISO | RGD:70502 | 6480464 | sodium bichromate results in increased expression of TP53 mRNA; sodium bichromate results in increased expression more ... | CTD | PMID:10942736|PMID:26091798 |
Tp53 | Rat | sodium dichromate | multiple interactions | ISO | RGD:70502 | 6480464 | [sodium bichromate results in increased abundance of chromium hexavalent ion] which results in increased activity more ... | CTD | PMID:10942736|PMID:14971653 |
Tp53 | Rat | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of TP53 mRNA | CTD | PMID:11960910 |
Tp53 | Rat | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of TP53 mRNA | CTD | PMID:22561333 |
Tp53 | Rat | sodium dichromate | increases phosphorylation | ISO | RGD:11440 | 6480464 | sodium bichromate results in increased phosphorylation of TRP53 protein | CTD | PMID:20298709 |
Tp53 | Rat | sodium disulfite | decreases expression | ISO | RGD:70502 | 6480464 | sodium metabisulfite results in decreased expression of TP53 mRNA | CTD | PMID:35067933 |
Tp53 | Rat | sodium fluoride | increases expression | ISO | RGD:70502 | 6480464 | Sodium Fluoride results in increased expression of TP53 mRNA; Sodium Fluoride results in increased expression more ... | CTD | PMID:22525295|PMID:38342390 |
Tp53 | Rat | sodium fluoride | multiple interactions | ISO | RGD:11440 | 6480464 | 2-(2-(4-heptylphenyl)ethyl)-6-hydroxy-benzoic acid inhibits the reaction [Sodium Fluoride results in increased acetylation of TRP53 protein]; [2-(2-(4-heptylphenyl)ethyl)-6-hydroxy-benzoic more ... | CTD | PMID:30738887|PMID:31927229|PMID:35714946 |
Tp53 | Rat | sodium fluoride | increases expression | ISO | RGD:11440 | 6480464 | Sodium Fluoride results in increased expression of TRP53 mRNA | CTD | PMID:27862939|PMID:30225638 |
Tp53 | Rat | sodium fluoride | increases acetylation | ISO | RGD:11440 | 6480464 | Sodium Fluoride results in increased acetylation of TRP53 protein | CTD | PMID:31927229 |
Tp53 | Rat | sodium hydrogencarbonate | multiple interactions | ISO | RGD:11440 | 6480464 | [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization more ... | CTD | PMID:25559736 |
Tp53 | Rat | Sodium salicylate | multiple interactions | EXP | | 6480464 | Sodium Salicylate inhibits the reaction [Paraquat results in increased expression of TP53 protein] | CTD | PMID:17561093 |
Tp53 | Rat | Soman | increases expression | ISO | RGD:11440 | 6480464 | Soman results in increased expression of TRP53 protein | CTD | PMID:16054742 |
Tp53 | Rat | sorafenib | multiple interactions | ISO | RGD:70502 | 6480464 | sorafenib promotes the reaction [GSK3B protein results in increased phosphorylation of TP53 protein] | CTD | PMID:17991738 |
Tp53 | Rat | spermidine | multiple interactions | EXP | | 6480464 | Spermidine inhibits the reaction [Eflornithine results in increased expression of TP53 mRNA] | CTD | PMID:11502571 |
Tp53 | Rat | starch | multiple interactions | ISO | RGD:11440 | 6480464 | Starch inhibits the reaction [Ethanol results in increased expression of TP53 mRNA] | CTD | PMID:28849987 |
Tp53 | Rat | staurosporine | multiple interactions | ISO | RGD:70502 | 6480464 | Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein more ... | CTD | PMID:15542774 |
Tp53 | Rat | staurosporine | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 protein affects the reaction [HR protein affects the reaction [Staurosporine results in increased activity more ... | CTD | PMID:20886113 |
Tp53 | Rat | staurosporine | multiple interactions | EXP | | 6480464 | HR protein inhibits the reaction [Staurosporine results in increased expression of TP53 protein] | CTD | PMID:20886113 |
Tp53 | Rat | sterigmatocystin | increases expression | EXP | | 6480464 | Sterigmatocystin results in increased expression of TP53 mRNA | CTD | PMID:34126181 |
Tp53 | Rat | stilbenoid | increases expression | ISO | RGD:70502 | 6480464 | [Stilbenes results in increased expression of TP53 protein] which results in increased expression of BAX more ... | CTD | PMID:23059970 |
Tp53 | Rat | streptozocin | multiple interactions | ISO | RGD:11440 | 6480464 | 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; [Dietary Fats more ... | CTD | PMID:11375343|PMID:22744176|PMID:29059224|PMID:29673160|PMID:38483099 |
Tp53 | Rat | streptozocin | increases expression | EXP | | 6480464 | Streptozocin results in increased expression of TP53 mRNA; Streptozocin results in increased expression of TP53 more ... | CTD | PMID:15976052|PMID:23792339|PMID:30817903|PMID:30980806|PMID:33387473 |
Tp53 | Rat | streptozocin | multiple interactions | EXP | | 6480464 | 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; [Dietary Fats more ... | CTD | PMID:23792339|PMID:30817903|PMID:30980806|PMID:33387473|PMID:34391751 |
Tp53 | Rat | streptozocin | increases expression | ISO | RGD:11440 | 6480464 | Streptozocin results in increased expression of TRP53; Streptozocin results in increased expression of TRP53 mRNA; more ... | CTD | PMID:11375343|PMID:22744176|PMID:29059224|PMID:29673160 |
Tp53 | Rat | styrene oxide | affects expression | ISO | RGD:70502 | 6480464 | styrene oxide affects the expression of TP53 mRNA | CTD | PMID:11230554 |
Tp53 | Rat | succimer | multiple interactions | EXP | | 6480464 | Succimer inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in more ... | CTD | PMID:31163222|PMID:32402895 |
Tp53 | Rat | sucrose | multiple interactions | ISO | RGD:11440 | 6480464 | 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of more ... | CTD | PMID:15975986|PMID:37516258 |
Tp53 | Rat | sulforaphane | multiple interactions | ISO | RGD:11440 | 6480464 | sulforaphane inhibits the reaction [TRP53 gene mutant form results in decreased susceptibility to Doxorubicin]; sulforaphane more ... | CTD | PMID:16843502|PMID:17404018 |
Tp53 | Rat | sulforaphane | multiple interactions | ISO | RGD:70502 | 6480464 | sulforaphane inhibits the reaction [triptolide results in increased expression of TP53 protein] | CTD | PMID:36990132 |
Tp53 | Rat | sulforaphane | decreases expression | ISO | RGD:70502 | 6480464 | sulforaphane results in decreased expression of TP53 protein | CTD | PMID:27878984 |
Tp53 | Rat | sulfotep | affects activity | ISO | RGD:70502 | 6480464 | sulfotepp metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | sulfur dioxide | multiple interactions | EXP | | 6480464 | [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 mRNA; [Sulfur Dioxide co-treated more ... | CTD | PMID:19408242|PMID:20064080|PMID:30503585 |
Tp53 | Rat | sulfur dioxide | multiple interactions | ISO | RGD:11440 | 6480464 | [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of more ... | CTD | PMID:27521637 |
Tp53 | Rat | sulfur dioxide | increases expression | EXP | | 6480464 | Sulfur Dioxide results in increased expression of TP53 mRNA; Sulfur Dioxide results in increased expression more ... | CTD | PMID:19408242|PMID:19434695|PMID:20064080 |
Tp53 | Rat | sulindac | multiple interactions | ISO | RGD:70502 | 6480464 | [Sulindac results in increased abundance of Reactive Oxygen Species] which results in increased activity of more ... | CTD | PMID:17136320 |
Tp53 | Rat | sulindac | decreases expression | ISO | RGD:11440 | 6480464 | Sulindac results in decreased expression of TRP53 protein | CTD | PMID:15020200 |
Tp53 | Rat | sulindac | increases expression | ISO | RGD:70502 | 6480464 | Sulindac results in increased expression of TP53 protein | CTD | PMID:15713900 |
Tp53 | Rat | sulindac | affects localization | ISO | RGD:70502 | 6480464 | Sulindac affects the localization of TP53 protein | CTD | PMID:17136320 |
Tp53 | Rat | sulindac sulfide | decreases expression | ISO | RGD:70502 | 6480464 | sulindac sulfide results in decreased expression of TP53 protein | CTD | PMID:9192825 |
Tp53 | Rat | sulprofos | affects activity | ISO | RGD:70502 | 6480464 | sulprofos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | sunitinib | increases expression | ISO | RGD:70502 | 150537096 | Sunitinib increases expression of TP53 mRNA and protein in breast epithelium | RGD | |
Tp53 | Rat | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of TP53 protein | CTD | PMID:38101598 |
Tp53 | Rat | sunitinib | increases expression | ISO | RGD:11440 | 6480464 | Sunitinib results in increased expression of TP53 protein | CTD | PMID:38101598 |
Tp53 | Rat | suramin | multiple interactions | ISO | RGD:70502 | 6480464 | Suramin results in decreased activity of [SIRT1 protein results in decreased acetylation of TP53 protein] | CTD | PMID:18482975 |
Tp53 | Rat | swainsonine | increases expression | ISO | RGD:11440 | 6480464 | Swainsonine results in increased expression of TRP53 protein | CTD | PMID:36402259 |
Tp53 | Rat | syringic acid | increases expression | ISO | RGD:70502 | 6480464 | syringic acid results in increased expression of TP53 protein | CTD | PMID:33548266 |
Tp53 | Rat | syringin | increases expression | ISO | RGD:70502 | 6480464 | syringin results in increased expression of TP53 protein | CTD | PMID:35580997 |
Tp53 | Rat | T-2 toxin | increases expression | ISO | RGD:70502 | 6480464 | T-2 Toxin results in increased expression of TP53 protein | CTD | PMID:19524637 |
Tp53 | Rat | T-2 toxin | decreases expression | ISO | RGD:70502 | 6480464 | T-2 Toxin results in decreased expression of TP53 mRNA | CTD | PMID:34581912 |
Tp53 | Rat | T-2 toxin | increases expression | ISO | RGD:11440 | 6480464 | T-2 Toxin results in increased expression of TRP53 mRNA; T-2 Toxin results in increased expression more ... | CTD | PMID:29432840 |
Tp53 | Rat | T-2 toxin | increases expression | EXP | | 6480464 | T-2 Toxin results in increased expression of TP53 mRNA; T-2 Toxin results in increased expression more ... | CTD | PMID:21296132|PMID:29567467|PMID:29870751 |
Tp53 | Rat | tacrine | multiple interactions | EXP | | 6480464 | Tacrine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]; Tacrine inhibits more ... | CTD | PMID:12414117 |
Tp53 | Rat | tacrolimus hydrate | multiple interactions | EXP | | 6480464 | Tacrolimus inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] | CTD | PMID:12642403 |
Tp53 | Rat | tacrolimus hydrate | multiple interactions | ISO | RGD:11440 | 6480464 | Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TRP53 more ... | CTD | PMID:10205001 |
Tp53 | Rat | tamoxifen | increases expression | ISO | RGD:70502 | 6480464 | Tamoxifen results in increased expression of TP53 mRNA; Tamoxifen results in increased expression of TP53 more ... | CTD | PMID:16450001|PMID:20549698|PMID:30153467|PMID:32530119|PMID:34821461 |
Tp53 | Rat | tamoxifen | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 gene mutant form results in decreased susceptibility to Tamoxifen | CTD | PMID:10786679 |
Tp53 | Rat | tamoxifen | affects expression | ISO | RGD:11440 | 6480464 | Tamoxifen affects the expression of TRP53 mRNA | CTD | PMID:17555576 |
Tp53 | Rat | tamoxifen | increases mutagenesis | EXP | | 6480464 | Tamoxifen results in increased mutagenesis of TP53 gene | CTD | PMID:8033108 |
Tp53 | Rat | tamoxifen | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Tamoxifen | CTD | PMID:20549698 |
Tp53 | Rat | tamoxifen | multiple interactions | ISO | RGD:70502 | 6480464 | [Tamoxifen co-treated with naringenin] results in increased expression of TP53 mRNA; Tamoxifen affects the reaction more ... | CTD | PMID:20549698|PMID:30153467|PMID:31681507|PMID:32530119 |
Tp53 | Rat | tamoxifen | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Tamoxifen | CTD | PMID:15832264 |
Tp53 | Rat | tanespimycin | decreases expression | ISO | RGD:70502 | 6480464 | tanespimycin results in decreased expression of TP53 protein | CTD | PMID:10564678 |
Tp53 | Rat | Tanshinone I | increases expression | ISO | RGD:70502 | 6480464 | tanshinone results in increased expression of TP53 protein | CTD | PMID:16009009 |
Tp53 | Rat | Tanshinone I | decreases expression | ISO | RGD:11440 | 6480464 | tanshinone results in decreased expression of TRP53 mRNA | CTD | PMID:36819991 |
Tp53 | Rat | Tanshinone I | decreases expression | ISO | RGD:70502 | 6480464 | tanshinone results in decreased expression of TP53 protein | CTD | PMID:19885617|PMID:20369472 |
Tp53 | Rat | taurine | multiple interactions | EXP | | 6480464 | Taurine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TRP53 mRNA]; Taurine inhibits the more ... | CTD | PMID:30101532 |
Tp53 | Rat | tauroursodeoxycholic acid | multiple interactions | EXP | | 6480464 | ursodoxicoltaurine inhibits the reaction [TP53 protein results in increased expression of BAX mRNA]; ursodoxicoltaurine results more ... | CTD | PMID:15255934|PMID:17881359 |
Tp53 | Rat | tauroursodeoxycholic acid | multiple interactions | ISO | RGD:70502 | 6480464 | ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results more ... | CTD | PMID:16923170 |
Tp53 | Rat | tauroursodeoxycholic acid | affects response to substance | EXP | | 6480464 | TP53 protein affects the susceptibility to ursodoxicoltaurine | CTD | PMID:17431217 |
Tp53 | Rat | Tegafur | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to [Uracil co-treated with Tegafur] | CTD | PMID:15182437 |
Tp53 | Rat | Tegafur | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Tegafur | CTD | PMID:15182437 |
Tp53 | Rat | temozolomide | multiple interactions | ISO | RGD:70502 | 6480464 | [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to more ... | CTD | PMID:17216584|PMID:20980775|PMID:29164620|PMID:32800223 |
Tp53 | Rat | temozolomide | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 protein affects the reaction [[temozolomide co-treated with O(6)-benzylguanine] results in increased expression of BAX more ... | CTD | PMID:20980775 |
Tp53 | Rat | temozolomide | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to temozolomide | CTD | PMID:16405512 |
Tp53 | Rat | temozolomide | decreases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in decreased susceptibility to temozolomide | CTD | PMID:16193384 |
Tp53 | Rat | temozolomide | increases expression | ISO | RGD:70502 | 6480464 | temozolomide results in increased expression of TP53 protein | CTD | PMID:16193384 |
Tp53 | Rat | tenofovir disoproxil fumarate | multiple interactions | ISO | RGD:70502 | 6480464 | [Emtricitabine co-treated with Tenofovir] results in increased expression of TP53 protein | CTD | PMID:31545371 |
Tp53 | Rat | tenofovir disoproxil fumarate | increases expression | ISO | RGD:70502 | 6480464 | Tenofovir results in increased expression of TP53 protein | CTD | PMID:31545371 |
Tp53 | Rat | terbufos | affects activity | ISO | RGD:70502 | 6480464 | terbufos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | terbutylazine | multiple interactions | ISO | RGD:70502 | 6480464 | terbutylazine results in decreased stability of and results in increased degradation of and results in more ... | CTD | PMID:22445671 |
Tp53 | Rat | Terfenadine | increases expression | ISO | RGD:70502 | 6480464 | Terfenadine results in increased expression of TP53 protein | CTD | PMID:12244568 |
Tp53 | Rat | teriflunomide | increases expression | ISO | RGD:70502 | 6480464 | teriflunomide results in increased expression of TP53 mRNA; teriflunomide results in increased expression of TP53 more ... | CTD | PMID:10076546 |
Tp53 | Rat | tert-butyl hydroperoxide | multiple interactions | ISO | RGD:70502 | 6480464 | [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of TP53 mRNA; Antineoplastic Agents, Immunological inhibits more ... | CTD | PMID:12782109|PMID:17555331|PMID:35690295 |
Tp53 | Rat | tert-butyl hydroperoxide | increases expression | ISO | RGD:11440 | 6480464 | tert-Butylhydroperoxide results in increased expression of TRP53 mRNA; tert-Butylhydroperoxide results in increased expression of TRP53 more ... | CTD | PMID:18619952 |
Tp53 | Rat | tert-butyl hydroperoxide | increases phosphorylation | ISO | RGD:11440 | 6480464 | tert-Butylhydroperoxide results in increased phosphorylation of TRP53 protein | CTD | PMID:15879681 |
Tp53 | Rat | tert-butyl hydroperoxide | multiple interactions | ISO | RGD:11440 | 6480464 | Catechin inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of TRP53 protein] | CTD | PMID:15879681 |
Tp53 | Rat | tert-butyl hydroperoxide | increases glutathionylation | ISO | RGD:70502 | 6480464 | tert-Butylhydroperoxide results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | tert-butyl hydroperoxide | increases expression | ISO | RGD:70502 | 6480464 | tert-Butylhydroperoxide results in increased expression of TP53 protein | CTD | PMID:12782109 |
Tp53 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | RGD:70502 | 6480464 | tert-Butylhydroperoxide results in decreased expression of TP53 mRNA | CTD | PMID:12419474 |
Tp53 | Rat | testosterone | multiple interactions | EXP | | 6480464 | chrysin inhibits the reaction [Testosterone results in decreased expression of TP53 mRNA] | CTD | PMID:29247772 |
Tp53 | Rat | testosterone | decreases expression | EXP | | 6480464 | Testosterone results in decreased expression of TP53 mRNA | CTD | PMID:29247772 |
Tp53 | Rat | testosterone | decreases expression | ISO | RGD:11440 | 6480464 | Testosterone results in decreased expression of TRP53 protein | CTD | PMID:18030663 |
Tp53 | Rat | testosterone | multiple interactions | ISO | RGD:11440 | 6480464 | gingerol inhibits the reaction [Testosterone results in decreased expression of TRP53 protein] | CTD | PMID:18030663 |
Tp53 | Rat | testosterone | multiple interactions | ISO | RGD:70502 | 6480464 | [Testosterone co-treated with gingerol] results in increased expression of TP53 protein | CTD | PMID:18030663 |
Tp53 | Rat | tetrachloroethene | increases expression | ISO | RGD:70502 | 6480464 | Tetrachloroethylene results in increased expression of TP53 protein | CTD | PMID:12160929 |
Tp53 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of TP53 mRNA | CTD | PMID:17522070|PMID:31150632 |
Tp53 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TP53 mRNA] | CTD | PMID:31150632 |
Tp53 | Rat | tetrachloromethane | multiple interactions | ISO | RGD:11440 | 6480464 | Lipids inhibits the reaction [Carbon Tetrachloride results in increased expression of TRP53 protein]; Rutin inhibits more ... | CTD | PMID:25445725|PMID:29522708 |
Tp53 | Rat | tetrachloromethane | increases expression | ISO | RGD:11440 | 6480464 | Carbon Tetrachloride results in increased expression of TRP53 protein | CTD | PMID:25445725|PMID:29522708 |
Tp53 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TP53 mRNA | CTD | PMID:17256749 |
Tp53 | Rat | tetrachlorvinphos | affects activity | ISO | RGD:70502 | 6480464 | Tetrachlorvinphos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | tetracycline | increases expression | EXP | | 6480464 | Tetracycline results in increased expression of TP53 mRNA | CTD | PMID:17522070 |
Tp53 | Rat | tetraphene | multiple interactions | ISO | RGD:11440 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... | CTD | PMID:22120587|PMID:27858113 |
Tp53 | Rat | tetraphene | increases expression | ISO | RGD:11440 | 6480464 | benz(a)anthracene results in increased expression of TRP53 protein | CTD | PMID:22120587 |
Tp53 | Rat | tetrathiomolybdate(2-) | multiple interactions | EXP | | 6480464 | [Copper deficiency co-treated with tetrathiomolybdate] results in increased expression of TP53 protein | CTD | PMID:22276220 |
Tp53 | Rat | tetrathiomolybdate(2-) | increases phosphorylation | ISO | RGD:70502 | 6480464 | tetrathiomolybdate results in increased phosphorylation of TP53 protein | CTD | PMID:37290678 |
Tp53 | Rat | tetrazolium violet | increases expression | ISO | RGD:11440 | 6480464 | tetrazolium violet results in increased expression of TRP53 protein | CTD | PMID:18547555 |
Tp53 | Rat | thalidomide | increases expression | ISO | RGD:70502 | 6480464 | Thalidomide analog results in increased expression of TP53 mRNA | CTD | PMID:20525221 |
Tp53 | Rat | thapsigargin | decreases expression | ISO | RGD:70502 | 6480464 | Thapsigargin results in decreased expression of TP53 mRNA | CTD | PMID:19442820 |
Tp53 | Rat | thapsigargin | multiple interactions | ISO | RGD:70502 | 6480464 | caffeic acid promotes the reaction [Thapsigargin results in decreased expression of TP53 mRNA] | CTD | PMID:19442820 |
Tp53 | Rat | theaflavin | multiple interactions | ISO | RGD:11440 | 6480464 | [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased more ... | CTD | PMID:18656336|PMID:23717041 |
Tp53 | Rat | theophylline | multiple interactions | ISO | RGD:70502 | 6480464 | [Theophylline co-treated with Chlorambucil] results in increased expression of TP53; IL4 protein inhibits the reaction more ... | CTD | PMID:8822937 |
Tp53 | Rat | theophylline | decreases expression | EXP | | 6480464 | Theophylline results in decreased expression of TP53 mRNA | CTD | PMID:17522070 |
Tp53 | Rat | theophylline | decreases expression | ISO | RGD:70502 | 6480464 | Theophylline results in decreased expression of TP53 | CTD | PMID:8822937 |
Tp53 | Rat | thiabendazole | increases expression | EXP | | 6480464 | Thiabendazole results in increased expression of TP53 mRNA | CTD | PMID:18539377 |
Tp53 | Rat | thimerosal | affects activity | ISO | RGD:70502 | 6480464 | Thimerosal affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | thioacetamide | multiple interactions | EXP | | 6480464 | Thioacetamide results in increased expression of and results in increased phosphorylation of and results in more ... | CTD | PMID:16937528 |
Tp53 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TP53 mRNA; Thioacetamide results in increased expression of TP53 more ... | CTD | PMID:23411599|PMID:26011634|PMID:34492290 |
Tp53 | Rat | Thiobencarb | affects activity | ISO | RGD:70502 | 6480464 | benthiocarb metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Thioinosine | affects activity | ISO | RGD:70502 | 6480464 | Thioinosine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | thioridazine | affects activity | ISO | RGD:70502 | 6480464 | Thioridazine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | thiostrepton | decreases expression | ISO | RGD:70502 | 6480464 | Thiostrepton results in decreased expression of TP53 mRNA; Thiostrepton results in decreased expression of TP53 more ... | CTD | PMID:22321511 |
Tp53 | Rat | thiourea | multiple interactions | ISO | RGD:70502 | 6480464 | Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 more ... | CTD | PMID:29803612 |
Tp53 | Rat | thiram | decreases expression | ISO | RGD:70502 | 6480464 | Thiram results in decreased expression of TP53 mRNA | CTD | PMID:38568856 |
Tp53 | Rat | thymoquinone | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of TP53 protein] | CTD | PMID:31433961 |
Tp53 | Rat | thymoquinone | multiple interactions | ISO | RGD:11440 | 6480464 | thymoquinone inhibits the reaction [Benzo(a)pyrene results in decreased expression of TP53 protein] | CTD | PMID:36193556 |
Tp53 | Rat | thymoquinone | increases expression | ISO | RGD:70502 | 6480464 | thymoquinone results in increased expression of TP53 protein | CTD | PMID:21609759|PMID:31433961|PMID:34627931 |
Tp53 | Rat | thyroxine | affects localization | EXP | | 6480464 | Thyroxine affects the localization of TP53 protein modified form | CTD | PMID:17984113 |
Tp53 | Rat | thyroxine | multiple interactions | EXP | | 6480464 | tetraiodothyroacetic acid inhibits the reaction [Thyroxine affects the localization of TP53 protein modified form] | CTD | PMID:17984113 |
Tp53 | Rat | tioguanine | increases activity | ISO | RGD:70502 | 6480464 | Thioguanine results in increased activity of TP53 protein | CTD | PMID:22010212 |
Tp53 | Rat | tipifarnib | decreases expression | EXP | | 6480464 | tipifarnib results in decreased expression of TP53 mRNA | CTD | PMID:16403772 |
Tp53 | Rat | tirapazamine | increases expression | ISO | RGD:70502 | 6480464 | tirapazamine results in increased expression of TP53 | CTD | PMID:15814660 |
Tp53 | Rat | tirapazamine | increases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein mutant form results in increased susceptibility to tirapazamine | CTD | PMID:16012721 |
Tp53 | Rat | tirapazamine | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 results in increased susceptibility to tirapazamine | CTD | PMID:15814660 |
Tp53 | Rat | tiratricol | affects activity | ISO | RGD:70502 | 6480464 | 3,3',5-triiodothyroacetic acid affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | Tiron | multiple interactions | EXP | | 6480464 | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 protein]; more ... | CTD | PMID:39214269 |
Tp53 | Rat | titanium dioxide | multiple interactions | ISO | RGD:11440 | 6480464 | chlorophyllin inhibits the reaction [titanium dioxide results in increased mutagenesis of TRP53 exon] | CTD | PMID:25129858 |
Tp53 | Rat | titanium dioxide | increases phosphorylation | ISO | RGD:70502 | 6480464 | titanium dioxide results in increased phosphorylation of TP53 protein | CTD | PMID:30126039 |
Tp53 | Rat | titanium dioxide | multiple interactions | ISO | RGD:70502 | 6480464 | [Ferrosoferric Oxide binds to titanium dioxide] which results in increased expression of TP53 protein; titanium more ... | CTD | PMID:30098274|PMID:30738203 |
Tp53 | Rat | titanium dioxide | increases expression | ISO | RGD:11440 | 6480464 | titanium dioxide results in increased expression of TRP53 mRNA | CTD | PMID:29128614|PMID:29264374 |
Tp53 | Rat | titanium dioxide | increases phosphorylation | EXP | | 6480464 | titanium dioxide results in increased phosphorylation of TP53 protein | CTD | PMID:20863874 |
Tp53 | Rat | titanium dioxide | increases expression | ISO | RGD:70502 | 6480464 | titanium dioxide results in increased expression of TP53; titanium dioxide results in increased expression of more ... | CTD | PMID:19695317|PMID:20362650|PMID:21067279|PMID:23111874|PMID:30098274|PMID:30910687 |
Tp53 | Rat | titanium dioxide | increases mutagenesis | ISO | RGD:11440 | 6480464 | titanium dioxide results in increased mutagenesis of TRP53 exon | CTD | PMID:25129858 |
Tp53 | Rat | tocopherol | increases activity | ISO | RGD:70502 | 6480464 | Tocopherols results in increased activity of TP53 protein | CTD | PMID:15883045 |
Tp53 | Rat | tolbutamide | increases expression | EXP | | 6480464 | Tolbutamide results in increased expression of TP53 mRNA | CTD | PMID:16426753 |
Tp53 | Rat | toluene | increases phosphorylation | ISO | RGD:70502 | 6480464 | Toluene results in increased phosphorylation of TP53 protein | CTD | PMID:8076368 |
Tp53 | Rat | toluene | multiple interactions | EXP | | 6480464 | Toluene results in increased phosphorylation of and results in increased activity of TP53 protein | CTD | PMID:9118908 |
Tp53 | Rat | toluene | increases phosphorylation | EXP | | 6480464 | Toluene results in increased phosphorylation of TP53 protein | CTD | PMID:8076368 |
Tp53 | Rat | Tomentosin | increases expression | ISO | RGD:70502 | 6480464 | tomentosin results in increased expression of TP53 protein | CTD | PMID:27922187 |
Tp53 | Rat | Tomentosin | multiple interactions | ISO | RGD:70502 | 6480464 | Caffeine inhibits the reaction [tomentosin results in increased phosphorylation of TP53 protein]; tomentosin results in more ... | CTD | PMID:17919456|PMID:32787465 |
Tp53 | Rat | toosendanin | decreases expression | ISO | RGD:70502 | 6480464 | toosendanin analog results in decreased expression of TP53 protein; toosendanin results in decreased expression of more ... | CTD | PMID:36781147 |
Tp53 | Rat | topotecan | multiple interactions | ISO | RGD:70502 | 6480464 | [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with Topotecan] promotes the reaction [TP53 protein binds to BAX promoter]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide more ... | CTD | PMID:19812371|PMID:23376119|PMID:25667043 |
Tp53 | Rat | topotecan | affects activity | ISO | RGD:70502 | 6480464 | Topotecan affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | topotecan | increases phosphorylation | ISO | RGD:70502 | 6480464 | Topotecan results in increased phosphorylation of TP53 protein | CTD | PMID:25667043 |
Tp53 | Rat | topotecan | increases expression | ISO | RGD:70502 | 6480464 | Topotecan results in increased expression of TP53 protein | CTD | PMID:12698201|PMID:20038611|PMID:23376119 |
Tp53 | Rat | topotecan | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 inhibits the reaction [Topotecan results in increased activity of CASP3 protein]; TRP53 inhibits the more ... | CTD | PMID:19812371 |
Tp53 | Rat | topotecan | increases activity | ISO | RGD:70502 | 6480464 | Topotecan results in increased activity of TP53 protein | CTD | PMID:12698201|PMID:30818834 |
Tp53 | Rat | trans-caffeic acid | multiple interactions | ISO | RGD:70502 | 6480464 | caffeic acid promotes the reaction [Thapsigargin results in decreased expression of TP53 mRNA] | CTD | PMID:19442820 |
Tp53 | Rat | trans-caffeic acid | affects expression | ISO | RGD:70502 | 6480464 | caffeic acid affects the expression of TP53 protein | CTD | PMID:11522280 |
Tp53 | Rat | trans-piceid | multiple interactions | EXP | | 6480464 | polydatin inhibits the reaction [Arsenic Trioxide results in increased expression of TP53 mRNA] | CTD | PMID:29130132 |
Tp53 | Rat | trans-pinosylvin | increases expression | ISO | RGD:70502 | 6480464 | pinosylvin results in increased expression of TP53 protein | CTD | PMID:23333577 |
Tp53 | Rat | triamterene | affects activity | ISO | RGD:70502 | 6480464 | Triamterene affects the activity of TP53 protein; Triamterene metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | triazophos | affects activity | ISO | RGD:70502 | 6480464 | triazophos metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | tribufos | affects activity | ISO | RGD:70502 | 6480464 | butyl phosphorotrithioate metabolite affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | tributylstannane | increases expression | ISO | RGD:70502 | 6480464 | tributyltin results in increased expression of TP53 protein | CTD | PMID:25743928|PMID:36319700 |
Tp53 | Rat | tributylstannane | multiple interactions | ISO | RGD:70502 | 6480464 | 2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [tributyltin results in increased expression of TP53 protein]; pyrazolanthrone inhibits the more ... | CTD | PMID:36319700 |
Tp53 | Rat | tributylstannane | increases expression | ISO | RGD:11440 | 6480464 | tributyltin results in increased expression of TRP53 protein | CTD | PMID:33720505|PMID:36319700 |
Tp53 | Rat | tributylstannane | decreases expression | ISO | RGD:70502 | 6480464 | tributyltin results in decreased expression of TP53 protein | CTD | PMID:26961604 |
Tp53 | Rat | trichlorfon | increases expression | ISO | RGD:70502 | 6480464 | Trichlorfon results in increased expression of TP53 protein | CTD | PMID:19631781 |
Tp53 | Rat | trichloroethene | increases expression | ISO | RGD:70502 | 6480464 | Trichloroethylene results in increased expression of TP53 protein | CTD | PMID:12160929 |
Tp53 | Rat | trichostatin A | multiple interactions | ISO | RGD:70502 | 6480464 | [Genistein co-treated with trichostatin A] results in increased expression of TP53 protein; anacardic acid inhibits more ... | CTD | PMID:15964798|PMID:16467109|PMID:20043870|PMID:22626855|PMID:25699604|PMID:26768552 |
Tp53 | Rat | trichostatin A | increases expression | ISO | RGD:70502 | 6480464 | trichostatin A results in increased expression of TP53 mRNA; trichostatin A results in increased expression more ... | CTD | PMID:16865256|PMID:25699604|PMID:26768552 |
Tp53 | Rat | trichostatin A | decreases expression | EXP | | 6480464 | trichostatin A results in decreased expression of TP53 mRNA | CTD | PMID:23558232 |
Tp53 | Rat | trichostatin A | decreases activity | EXP | | 6480464 | trichostatin A results in decreased activity of TP53 protein | CTD | PMID:16426753 |
Tp53 | Rat | trichostatin A | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to trichostatin A | CTD | PMID:16467109 |
Tp53 | Rat | trichostatin A | decreases expression | ISO | RGD:70502 | 6480464 | trichostatin A results in decreased expression of TP53 mRNA; trichostatin A results in decreased expression more ... | CTD | PMID:15179185|PMID:19606018 |
Tp53 | Rat | triclosan | decreases expression | ISO | RGD:70502 | 6480464 | Triclosan results in decreased expression of TP53 mRNA | CTD | PMID:34681664 |
Tp53 | Rat | triethyl phosphate | affects binding | ISO | RGD:70502 | 6480464 | triethyl phosphate binds to TP53 gene | CTD | PMID:25510514 |
Tp53 | Rat | trifluridine | affects activity | ISO | RGD:70502 | 6480464 | Trifluridine affects the activity of TP53 protein | CTD | PMID:35435491 |
Tp53 | Rat | trimethyl phosphate | affects binding | ISO | RGD:70502 | 6480464 | trimethyl phosphate binds to TP53 gene | CTD | PMID:25510514 |
Tp53 | Rat | trimethylenediamine | multiple interactions | ISO | RGD:70502 | 6480464 | [Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of TP53 protein; more ... | CTD | PMID:17327230 |
Tp53 | Rat | trimethyltin | increases activity | ISO | RGD:11440 | 6480464 | trimethyltin results in increased activity of TRP53 protein | CTD | PMID:22634143 |
Tp53 | Rat | triphenyl phosphate | affects binding | ISO | RGD:70502 | 6480464 | triphenyl phosphate binds to TP53 gene | CTD | PMID:25510514 |
Tp53 | Rat | triphenyl phosphate | affects expression | ISO | RGD:70502 | 6480464 | triphenyl phosphate affects the expression of TP53 mRNA | CTD | PMID:37042841 |
Tp53 | Rat | triphenyl phosphate | increases expression | ISO | RGD:70502 | 6480464 | triphenyl phosphate results in increased expression of TP53 mRNA | CTD | PMID:25510514 |
Tp53 | Rat | triphenylstannane | increases expression | ISO | RGD:70502 | 6480464 | triphenyltin results in increased expression of TP53 protein | CTD | PMID:25743928 |
Tp53 | Rat | Triptolide | increases expression | ISO | RGD:11440 | 6480464 | triptolide results in increased expression of TRP53 mRNA; triptolide results in increased expression of TRP53 more ... | CTD | PMID:26990902|PMID:30009776|PMID:32835833 |
Tp53 | Rat | Triptolide | multiple interactions | ISO | RGD:70502 | 6480464 | NFE2L2 protein inhibits the reaction [triptolide results in increased expression of TP53 protein]; sulforaphane inhibits more ... | CTD | PMID:36990132 |
Tp53 | Rat | Triptolide | affects localization | ISO | RGD:11440 | 6480464 | triptolide affects the localization of TRP53 protein | CTD | PMID:36990132 |
Tp53 | Rat | Triptolide | affects localization | EXP | | 6480464 | triptolide affects the localization of TP53 protein | CTD | PMID:31618665 |
Tp53 | Rat | Triptolide | multiple interactions | ISO | RGD:11440 | 6480464 | triptolide results in increased expression of and results in increased phosphorylation of TRP53 protein; TRP53 more ... | CTD | PMID:30009776|PMID:31618665 |
Tp53 | Rat | Triptolide | multiple interactions | EXP | | 6480464 | pifithrin inhibits the reaction [triptolide results in increased expression of and results in increased phosphorylation more ... | CTD | PMID:30009776|PMID:31618665 |
Tp53 | Rat | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of TP53 mRNA; triptolide results in increased expression of TP53 more ... | CTD | PMID:30009776 |
Tp53 | Rat | Triptolide | decreases response to substance | ISO | RGD:11440 | 6480464 | TRP53 gene mutant form results in decreased susceptibility to triptolide | CTD | PMID:30009776 |
Tp53 | Rat | triptonide | affects expression | ISO | RGD:11440 | 6480464 | triptonide affects the expression of TRP53 mRNA | CTD | PMID:33045310 |
Tp53 | Rat | tris(2,3-dibromopropyl) phosphate | increases expression | EXP | | 6480464 | tris(2,3-dibromopropyl)phosphate results in increased expression of TP53 protein | CTD | PMID:9163691 |
Tp53 | Rat | tris(2-chloroethyl) phosphate | affects binding | ISO | RGD:70502 | 6480464 | tris(chloroethyl)phosphate binds to TP53 gene | CTD | PMID:25510514 |
Tp53 | Rat | tris(2-chloroethyl) phosphate | decreases expression | ISO | RGD:70502 | 6480464 | tris(chloroethyl)phosphate results in decreased expression of TP53 protein | CTD | PMID:28886428 |
Tp53 | Rat | Tris(2-ethylhexyl) phosphate | affects binding | ISO | RGD:70502 | 6480464 | tris(2-ethylhexyl)phosphate binds to TP53 gene | CTD | PMID:25510514 |
Tp53 | Rat | troglitazone | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to troglitazone | CTD | PMID:12824901 |
Tp53 | Rat | troglitazone | increases expression | ISO | RGD:70502 | 6480464 | troglitazone results in increased expression of TP53 mRNA; troglitazone results in increased expression of TP53 more ... | CTD | PMID:12595159|PMID:12824901|PMID:16303758|PMID:16374840|PMID:17143939|PMID:19631733 |
Tp53 | Rat | troglitazone | decreases expression | ISO | RGD:70502 | 6480464 | troglitazone results in decreased expression of TP53 mRNA | CTD | PMID:19631733 |
Tp53 | Rat | troglitazone | multiple interactions | ISO | RGD:70502 | 6480464 | troglitazone promotes the reaction [TP53 protein results in increased expression of PRODH mRNA] | CTD | PMID:16303758 |
Tp53 | Rat | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of TP53 mRNA; troglitazone results in increased expression of TP53 more ... | CTD | PMID:11068018|PMID:15767042 |
Tp53 | Rat | tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate | multiple interactions | ISO | RGD:70502 | 6480464 | Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]; Atropine inhibits the more ... | CTD | PMID:12762645 |
Tp53 | Rat | tropisetron | multiple interactions | EXP | | 6480464 | Tropisetron inhibits the reaction [Streptozocin results in increased expression of TP53 protein] | CTD | PMID:33387473 |
Tp53 | Rat | Tryptanthrine | multiple interactions | ISO | RGD:70502 | 6480464 | tryptanthrine results in decreased expression of and results in increased degradation of TP53 protein | CTD | PMID:17482571 |
Tp53 | Rat | Tungsten carbide | multiple interactions | ISO | RGD:70502 | 6480464 | [tungsten carbide co-treated with Cobalt] results in increased expression of and results in increased stability more ... | CTD | PMID:23052192 |
Tp53 | Rat | tunicamycin | multiple interactions | ISO | RGD:70502 | 6480464 | Tunicamycin promotes the reaction [Capsaicin results in increased degradation of TP53 protein] | CTD | PMID:19699254 |
Tp53 | Rat | tunicamycin | multiple interactions | ISO | RGD:11440 | 6480464 | TRP53 protein affects the reaction [HR protein affects the reaction [Tunicamycin results in increased activity more ... | CTD | PMID:20886113 |
Tp53 | Rat | tunicamycin | multiple interactions | EXP | | 6480464 | HR protein inhibits the reaction [Tunicamycin results in increased expression of TP53 protein] | CTD | PMID:20886113 |
Tp53 | Rat | tyrphostin AG 1478 | multiple interactions | ISO | RGD:70502 | 6480464 | RTKI cpd inhibits the reaction [sodium arsenite results in increased expression of TP53 protein] | CTD | PMID:15734884 |
Tp53 | Rat | uracil | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to [Uracil co-treated with Tegafur] | CTD | PMID:15182437 |
Tp53 | Rat | urethane | multiple interactions | ISO | RGD:11440 | 6480464 | Freund's Adjuvant promotes the reaction [Urethane results in decreased expression of TRP53 mRNA]; IFNG protein more ... | CTD | PMID:12810352 |
Tp53 | Rat | urethane | decreases expression | ISO | RGD:11440 | 6480464 | Urethane results in decreased expression of TRP53 mRNA | CTD | PMID:11091364 |
Tp53 | Rat | uridine | multiple interactions | ISO | RGD:70502 | 6480464 | Uridine inhibits the reaction [celastrol results in increased expression of TP53 protein] | CTD | PMID:27374097 |
Tp53 | Rat | Urolithin A | increases expression | ISO | RGD:70502 | 6480464 | 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in increased expression of TP53 protein | CTD | PMID:32179165 |
Tp53 | Rat | ursodeoxycholic acid | multiple interactions | ISO | RGD:70502 | 6480464 | MDM2 mutant form inhibits the reaction [Ursodeoxycholic Acid results in increased ubiquitination of TP53 protein]; more ... | CTD | PMID:19728331|PMID:20807506 |
Tp53 | Rat | ursodeoxycholic acid | multiple interactions | ISO | RGD:11440 | 6480464 | Ursodeoxycholic Acid inhibits the reaction [Cisplatin results in increased expression of TRP53 protein] | CTD | PMID:18558085 |
Tp53 | Rat | ursodeoxycholic acid | affects localization | EXP | | 6480464 | Ursodeoxycholic Acid affects the localization of TP53 protein | CTD | PMID:17881359 |
Tp53 | Rat | ursodeoxycholic acid | affects response to substance | EXP | | 6480464 | TP53 protein affects the susceptibility to Ursodeoxycholic Acid | CTD | PMID:17431217 |
Tp53 | Rat | ursodeoxycholic acid | multiple interactions | EXP | | 6480464 | [Ursodeoxycholic Acid promotes the reaction [TP53 protein binds to MDM2 protein]] which results in increased more ... | CTD | PMID:14514686|PMID:15222754|PMID:17881359|PMID:20137712|PMID:20807506 |
Tp53 | Rat | ursodeoxycholic acid | increases ubiquitination | ISO | RGD:70502 | 6480464 | Ursodeoxycholic Acid results in increased ubiquitination of TP53 protein | CTD | PMID:20807506 |
Tp53 | Rat | usnic acid | decreases expression | ISO | RGD:70502 | 6480464 | usnic acid results in decreased expression of TP53 protein | CTD | PMID:22285236 |
Tp53 | Rat | usnic acid | multiple interactions | ISO | RGD:70502 | 6480464 | Acetylcysteine inhibits the reaction [usnic acid results in increased expression of TP53 protein] | CTD | PMID:31715134 |
Tp53 | Rat | usnic acid | increases expression | ISO | RGD:70502 | 6480464 | usnic acid results in increased expression of TP53 mRNA; usnic acid results in increased expression more ... | CTD | PMID:22285236|PMID:31715134|PMID:32508146 |
Tp53 | Rat | valproic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of TP53 mRNA | CTD | PMID:17183730 |
Tp53 | Rat | valproic acid | decreases expression | ISO | RGD:70502 | 6480464 | Valproic Acid results in decreased expression of TP53 mRNA | CTD | PMID:28001369|PMID:37210002 |
Tp53 | Rat | valproic acid | increases methylation | ISO | RGD:70502 | 6480464 | Valproic Acid results in increased methylation of TP53 gene | CTD | PMID:29154799 |
Tp53 | Rat | valproic acid | affects expression | ISO | RGD:70502 | 6480464 | Valproic Acid affects the expression of TP53 mRNA | CTD | PMID:25979313 |
Tp53 | Rat | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of TP53 protein | CTD | PMID:23562654 |
Tp53 | Rat | valproic acid | increases expression | ISO | RGD:70502 | 6480464 | Valproic Acid results in increased expression of TP53 mRNA | CTD | PMID:22580532|PMID:22814014 |
Tp53 | Rat | valproic acid | increases expression | ISO | RGD:11440 | 6480464 | Valproic Acid results in increased expression of TRP53 mRNA; Valproic Acid results in increased expression more ... | CTD | PMID:16112698|PMID:19850124|PMID:9098922 |
Tp53 | Rat | valproic acid | multiple interactions | ISO | RGD:11440 | 6480464 | Folic Acid inhibits the reaction [Valproic Acid results in increased expression of TRP53 protein] | CTD | PMID:16112698 |
Tp53 | Rat | valsartan | multiple interactions | EXP | | 6480464 | Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of TP53 mRNA]; Valsartan inhibits the more ... | CTD | PMID:32197949|PMID:34273911 |
Tp53 | Rat | vanadium atom | multiple interactions | EXP | | 6480464 | Vanadium inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of TP53 protein]; Vanadium promotes the more ... | CTD | PMID:15565650|PMID:18155637 |
Tp53 | Rat | vanadium atom | increases activity | ISO | RGD:70502 | 6480464 | Vanadium results in increased activity of TP53 protein | CTD | PMID:19000753 |
Tp53 | Rat | vanadium dioxide | increases expression | ISO | RGD:70502 | 6480464 | vanadium dioxide results in increased expression of TP53 protein | CTD | PMID:33913241 |
Tp53 | Rat | vanadium(0) | multiple interactions | EXP | | 6480464 | Vanadium inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of TP53 protein]; Vanadium promotes the more ... | CTD | PMID:15565650|PMID:18155637 |
Tp53 | Rat | vanadium(0) | increases activity | ISO | RGD:70502 | 6480464 | Vanadium results in increased activity of TP53 protein | CTD | PMID:19000753 |
Tp53 | Rat | vancomycin | increases expression | EXP | | 6480464 | Vancomycin results in increased expression of TP53 mRNA | CTD | PMID:39059777 |
Tp53 | Rat | vancomycin | multiple interactions | EXP | | 6480464 | sinapinic acid inhibits the reaction [Vancomycin results in increased expression of TP53 mRNA] | CTD | PMID:39059777 |
Tp53 | Rat | vanillin | decreases expression | ISO | RGD:70502 | 6480464 | vanillin results in decreased expression of TP53 mRNA | CTD | PMID:17178418 |
Tp53 | Rat | venlafaxine hydrochloride | multiple interactions | EXP | | 6480464 | Venlafaxine Hydrochloride inhibits the reaction [Cisplatin results in increased expression of TP53 protein] | CTD | PMID:29852128 |
Tp53 | Rat | venom | multiple interactions | ISO | RGD:70502 | 6480464 | Viper Venoms results in increased expression of and affects the localization of TP53 protein | CTD | PMID:27613483 |
Tp53 | Rat | versicolorin A | increases phosphorylation | ISO | RGD:70502 | 6480464 | versicolorin A results in increased phosphorylation of TP53 protein | CTD | PMID:32106047|PMID:33984424 |
Tp53 | Rat | vincaleukoblastine | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of JUN protein]; TP53 protein more ... | CTD | PMID:12221076 |
Tp53 | Rat | vinclozolin | increases expression | ISO | RGD:11440 | 6480464 | vinclozolin results in increased expression of TRP53 mRNA | CTD | PMID:18940246 |
Tp53 | Rat | vinclozolin | decreases expression | ISO | RGD:70502 | 6480464 | vinclozolin results in decreased expression of TP53 protein | CTD | PMID:36498866 |
Tp53 | Rat | vinclozolin | multiple interactions | EXP | | 6480464 | [Genistein co-treated with vinclozolin] results in decreased expression of TP53 mRNA | CTD | PMID:32827888 |
Tp53 | Rat | vincristine | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Vincristine | CTD | PMID:14704126 |
Tp53 | Rat | vincristine | increases glutathionylation | ISO | RGD:70502 | 6480464 | Vincristine results in increased glutathionylation of TP53 protein | CTD | PMID:17555331 |
Tp53 | Rat | vincristine | increases expression | ISO | RGD:70502 | 6480464 | Vincristine results in increased expression of TP53 protein | CTD | PMID:12082016|PMID:15131059 |
Tp53 | Rat | vincristine | multiple interactions | ISO | RGD:70502 | 6480464 | [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of more ... | CTD | PMID:9815696 |
Tp53 | Rat | vincristine | increases activity | ISO | RGD:70502 | 6480464 | Vincristine results in increased activity of TP53 protein | CTD | PMID:22010212 |
Tp53 | Rat | vitamin D | increases expression | ISO | RGD:70502 | 6480464 | Vitamin D results in increased expression of TP53 mRNA | CTD | PMID:36442531 |
Tp53 | Rat | vitamin E | multiple interactions | EXP | | 6480464 | [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 more ... | CTD | PMID:21628957|PMID:24759048|PMID:25439240 |
Tp53 | Rat | vitamin E | increases expression | ISO | RGD:70502 | 6480464 | Vitamin E results in increased expression of TP53 mRNA | CTD | PMID:19244175 |
Tp53 | Rat | vitamin E | multiple interactions | ISO | RGD:70502 | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of TP53 mRNA; [Vitamin E co-treated more ... | CTD | PMID:15837074|PMID:19244175|PMID:24664296|PMID:30935902 |
Tp53 | Rat | vorinostat | decreases expression | ISO | RGD:11440 | 6480464 | Vorinostat results in decreased expression of TRP53 mRNA; Vorinostat results in decreased expression of TRP53 more ... | CTD | PMID:32512035 |
Tp53 | Rat | vorinostat | increases activity | ISO | RGD:70502 | 6480464 | Vorinostat results in increased activity of TP53 protein | CTD | PMID:30818834 |
Tp53 | Rat | vorinostat | increases acetylation | ISO | RGD:70502 | 6480464 | vorinostat results in increased acetylation of TP53 protein | CTD | PMID:19084294 |
Tp53 | Rat | vorinostat | multiple interactions | ISO | RGD:70502 | 6480464 | [vorinostat co-treated with Bortezomib] results in increased expression of TP53 protein; vorinostat inhibits the reaction more ... | CTD | PMID:17351739|PMID:19631782|PMID:19810103|PMID:21532991 |
Tp53 | Rat | vorinostat | increases expression | ISO | RGD:70502 | 6480464 | vorinostat results in increased expression of TP53 protein | CTD | PMID:17351739 |
Tp53 | Rat | warfarin | increases degradation | ISO | RGD:70502 | 6480464 | Warfarin results in increased degradation of TP53 protein | CTD | PMID:14634213 |
Tp53 | Rat | warfarin | increases expression | ISO | RGD:11440 | 6480464 | Warfarin results in increased expression of TRP53 mRNA; Warfarin results in increased expression of TRP53 more ... | CTD | PMID:29358327 |
Tp53 | Rat | WIN 55212-2 | increases expression | ISO | RGD:70502 | 6480464 | (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of TP53 protein | CTD | PMID:30776504 |
Tp53 | Rat | withaferin A | increases expression | ISO | RGD:70502 | 6480464 | withaferin A results in increased expression of TP53 mRNA | CTD | PMID:22973447 |
Tp53 | Rat | withaferin A | affects binding | ISO | RGD:70502 | 6480464 | withaferin A binds to TP53 protein | CTD | PMID:22973447 |
Tp53 | Rat | withaferin A | multiple interactions | ISO | RGD:70502 | 6480464 | [withaferin A inhibits the reaction [HSPA9 protein binds to TP53 protein]] which affects the localization more ... | CTD | PMID:22973447 |
Tp53 | Rat | Withanone | increases expression | ISO | RGD:70502 | 6480464 | withanone results in increased expression of TP53 mRNA | CTD | PMID:22973447 |
Tp53 | Rat | Withanone | multiple interactions | ISO | RGD:70502 | 6480464 | [withanone inhibits the reaction [HSPA9 protein binds to TP53 protein]] which affects the localization of more ... | CTD | PMID:21573189|PMID:22155302 |
Tp53 | Rat | wogonin | increases expression | ISO | RGD:70502 | 6480464 | wogonin results in increased expression of TP53 protein | CTD | PMID:21457722 |
Tp53 | Rat | wortmannin | multiple interactions | ISO | RGD:70502 | 6480464 | Wortmannin inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of TP53 protein]; Wortmannin more ... | CTD | PMID:12676607|PMID:15489221|PMID:15837074|PMID:16024610|PMID:17534123|PMID:18298901|PMID:19111594|PMID:22119920|PMID:22290291 |
Tp53 | Rat | wortmannin | decreases phosphorylation | ISO | RGD:70502 | 6480464 | wortmannin results in decreased phosphorylation of TP53 protein | CTD | PMID:22119920 |
Tp53 | Rat | wortmannin | multiple interactions | EXP | | 6480464 | wortmannin inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 protein]; wortmannin inhibits the more ... | CTD | PMID:11751435 |
Tp53 | Rat | Xanthatin | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to xanthatin | CTD | PMID:29074359 |
Tp53 | Rat | Xanthatin | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein promotes the reaction [xanthatin results in decreased expression of CDC25C protein modified form]; more ... | CTD | PMID:29074359 |
Tp53 | Rat | xanthohumol | increases expression | ISO | RGD:70502 | 6480464 | xanthohumol results in increased expression of TP53; xanthohumol results in increased expression of TP53 mRNA; more ... | CTD | PMID:23085367|PMID:26297991|PMID:27317025 |
Tp53 | Rat | XMU-MP-1 | multiple interactions | ISO | RGD:70502 | 6480464 | XMU-MP-1 inhibits the reaction [evodiamine results in increased expression of TP53 protein] | CTD | PMID:32057900 |
Tp53 | Rat | Y-27632 | increases expression | ISO | RGD:70502 | 6480464 | Y 27632 results in increased expression of TP53 protein | CTD | PMID:11839765 |
Tp53 | Rat | Y-27632 | decreases expression | ISO | RGD:70502 | 6480464 | Y 27632 results in decreased expression of TP53 mRNA | CTD | PMID:20878077 |
Tp53 | Rat | Y-27632 | multiple interactions | ISO | RGD:70502 | 6480464 | TP53 protein promotes the reaction [Y 27632 results in decreased susceptibility to Cisplatin]; Y 27632 more ... | CTD | PMID:20878077 |
Tp53 | Rat | Y-27632 | affects response to substance | ISO | RGD:70502 | 6480464 | TP53 protein affects the susceptibility to Y 27632 | CTD | PMID:20878077 |
Tp53 | Rat | zearalenone | decreases expression | ISO | RGD:11440 | 6480464 | Zearalenone results in decreased expression of TRP53 mRNA; Zearalenone results in decreased expression of TRP53 more ... | CTD | PMID:24412631|PMID:27473017 |
Tp53 | Rat | zearalenone | increases expression | ISO | RGD:11440 | 6480464 | Zearalenone results in increased expression of TRP53 protein | CTD | PMID:26231423 |
Tp53 | Rat | zearalenone | multiple interactions | ISO | RGD:11440 | 6480464 | crocin inhibits the reaction [Zearalenone results in increased expression of TRP53 protein] | CTD | PMID:26231423 |
Tp53 | Rat | zearalenone | multiple interactions | ISO | RGD:70502 | 6480464 | [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of TP53 more ... | CTD | PMID:30668976 |
Tp53 | Rat | zearalenone | increases expression | ISO | RGD:70502 | 6480464 | Zearalenone results in increased expression of TP53 mRNA | CTD | PMID:30668976 |
Tp53 | Rat | zebularine | increases expression | ISO | RGD:70502 | 6480464 | pyrimidin-2-one beta-ribofuranoside results in increased expression of TP53 protein | CTD | PMID:23320119 |
Tp53 | Rat | zerumbone | decreases expression | ISO | RGD:70502 | 6480464 | zerumbone results in decreased expression of TP53 mRNA | CTD | PMID:36122806 |
Tp53 | Rat | zidovudine | increases expression | ISO | RGD:70502 | 6480464 | Zidovudine results in increased expression of TP53 protein | CTD | PMID:16797627 |
Tp53 | Rat | zinc acetate | multiple interactions | ISO | RGD:70502 | 6480464 | [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of more ... | CTD | PMID:20530418 |
Tp53 | Rat | zinc atom | affects expression | ISO | RGD:70502 | 6480464 | Zinc affects the expression of TP53 protein | CTD | PMID:16636310 |
Tp53 | Rat | zinc atom | affects localization | ISO | RGD:70502 | 6480464 | Zinc affects the localization of TP53 protein | CTD | PMID:12107073 |
Tp53 | Rat | zinc atom | decreases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein results in decreased susceptibility to Zinc deficiency | CTD | PMID:12517797 |
Tp53 | Rat | zinc atom | multiple interactions | EXP | | 6480464 | [SLC30A10 protein affects the abundance of Zinc] which affects the expression of TP53 protein; [SLC30A3 more ... | CTD | PMID:22427991 |
Tp53 | Rat | zinc atom | increases expression | ISO | RGD:70502 | 6480464 | Zinc deficiency results in increased expression of TP53 mRNA; Zinc results in increased expression of more ... | CTD | PMID:12888634|PMID:15880691|PMID:18356318 |
Tp53 | Rat | zinc atom | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Zinc | CTD | PMID:15880691 |
Tp53 | Rat | zinc atom | multiple interactions | ISO | RGD:70502 | 6480464 | sodium arsenite inhibits the reaction [Zinc binds to TP53 protein]; TP53 protein inhibits the reaction more ... | CTD | PMID:15880691|PMID:36087615 |
Tp53 | Rat | zinc atom | multiple interactions | ISO | RGD:11440 | 6480464 | [Zinc deficiency promotes the reaction [TRP53 gene mutant form results in increased susceptibility to nitrosobenzylmethylamine]] more ... | CTD | PMID:11864783|PMID:12517797 |
Tp53 | Rat | zinc atom | increases expression | ISO | RGD:11440 | 6480464 | Zinc results in increased expression of TRP53 mRNA; Zinc results in increased expression of TRP53 more ... | CTD | PMID:11864783 |
Tp53 | Rat | zinc atom | affects binding | ISO | RGD:70502 | 6480464 | Zinc binds to TP53 protein | CTD | PMID:17327663|PMID:36087615 |
Tp53 | Rat | zinc atom | affects folding | ISO | RGD:70502 | 6480464 | Zinc affects the folding of TP53 protein | CTD | PMID:16768444 |
Tp53 | Rat | zinc dichloride | multiple interactions | ISO | RGD:70502 | 6480464 | zinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased phosphorylation more ... | CTD | PMID:19714248 |
Tp53 | Rat | zinc molecular entity | increases expression | ISO | RGD:70502 | 6480464 | Zinc Compounds results in increased expression of TP53 mRNA; Zinc Compounds results in increased expression more ... | CTD | PMID:24035972 |
Tp53 | Rat | zinc oxide | multiple interactions | ISO | RGD:70502 | 6480464 | Zinc Oxide results in increased phosphorylation of and results in increased expression of TP53 protein | CTD | PMID:21903158 |
Tp53 | Rat | zinc oxide | increases expression | ISO | RGD:11440 | 6480464 | Zinc Oxide analog results in increased expression of TRP53 protein | CTD | PMID:24614525 |
Tp53 | Rat | zinc protoporphyrin | multiple interactions | ISO | RGD:70502 | 6480464 | [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [cobaltiprotoporphyrin results in more ... | CTD | PMID:18042465 |
Tp53 | Rat | zinc protoporphyrin | multiple interactions | ISO | RGD:11440 | 6480464 | zinc protoporphyrin inhibits the reaction [resveratrol inhibits the reaction [Doxorubicin results in increased expression of more ... | CTD | PMID:22763982 |
Tp53 | Rat | zinc protoporphyrin | multiple interactions | EXP | | 6480464 | zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in decreased expression of TP53 protein] | CTD | PMID:20357190 |
Tp53 | Rat | zinc pyrithione | increases expression | ISO | RGD:70502 | 6480464 | pyrithione zinc results in increased expression of TP53 mRNA; pyrithione zinc results in increased expression more ... | CTD | PMID:21424779|PMID:21557991 |
Tp53 | Rat | zinc pyrithione | multiple interactions | ISO | RGD:70502 | 6480464 | Pentetic Acid inhibits the reaction [pyrithione zinc results in increased expression of TP53 protein]; Pentetic more ... | CTD | PMID:20151177|PMID:21557991 |
Tp53 | Rat | zinc sulfate | multiple interactions | ISO | RGD:70502 | 6480464 | [Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased more ... | CTD | PMID:15001399|PMID:18951928 |
Tp53 | Rat | zinc(0) | affects expression | ISO | RGD:70502 | 6480464 | Zinc affects the expression of TP53 protein | CTD | PMID:16636310 |
Tp53 | Rat | zinc(0) | affects folding | ISO | RGD:70502 | 6480464 | Zinc affects the folding of TP53 protein | CTD | PMID:16768444 |
Tp53 | Rat | zinc(0) | affects binding | ISO | RGD:70502 | 6480464 | Zinc binds to TP53 protein | CTD | PMID:17327663|PMID:36087615 |
Tp53 | Rat | zinc(0) | increases expression | ISO | RGD:11440 | 6480464 | Zinc results in increased expression of TRP53 mRNA; Zinc results in increased expression of TRP53 more ... | CTD | PMID:11864783 |
Tp53 | Rat | zinc(0) | multiple interactions | ISO | RGD:11440 | 6480464 | [Zinc deficiency promotes the reaction [TRP53 gene mutant form results in increased susceptibility to nitrosobenzylmethylamine]] more ... | CTD | PMID:11864783|PMID:12517797 |
Tp53 | Rat | zinc(0) | multiple interactions | ISO | RGD:70502 | 6480464 | sodium arsenite inhibits the reaction [Zinc binds to TP53 protein]; TP53 protein inhibits the reaction more ... | CTD | PMID:15880691|PMID:36087615 |
Tp53 | Rat | zinc(0) | increases response to substance | ISO | RGD:70502 | 6480464 | TP53 protein results in increased susceptibility to Zinc | CTD | PMID:15880691 |
Tp53 | Rat | zinc(0) | increases expression | ISO | RGD:70502 | 6480464 | Zinc deficiency results in increased expression of TP53 mRNA; Zinc results in increased expression of more ... | CTD | PMID:12888634|PMID:15880691|PMID:18356318 |
Tp53 | Rat | zinc(0) | multiple interactions | EXP | | 6480464 | [SLC30A10 protein affects the abundance of Zinc] which affects the expression of TP53 protein; [SLC30A3 more ... | CTD | PMID:22427991 |
Tp53 | Rat | zinc(0) | decreases response to substance | ISO | RGD:11440 | 6480464 | TRP53 protein results in decreased susceptibility to Zinc deficiency | CTD | PMID:12517797 |
Tp53 | Rat | zinc(0) | affects localization | ISO | RGD:70502 | 6480464 | Zinc affects the localization of TP53 protein | CTD | PMID:12107073 |
Tp53 | Rat | zoledronic acid | affects activity | ISO | RGD:70502 | 6480464 | zoledronic acid affects the activity of TP53 protein | CTD | PMID:25596134 |
Tp53 | Rat | zoledronic acid | multiple interactions | ISO | RGD:70502 | 6480464 | [Tretinoin co-treated with zoledronic acid] results in decreased expression of TP53 protein | CTD | PMID:20349282 |
Tp53 | Rat | zoledronic acid | increases expression | ISO | RGD:70502 | 6480464 | Zoledronic Acid results in increased expression of TP53 mRNA | CTD | PMID:35587103 |
Tp53 | Rat | zoxamide | affects activity | ISO | RGD:70502 | 6480464 | zoxamide affects the activity of TP53 protein | CTD | PMID:35435491 |