Psmc2 (proteasome 26S subunit, ATPase 2) - Rat Genome Database

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Gene: Psmc2 (proteasome 26S subunit, ATPase 2) Rattus norvegicus
Analyze
Symbol: Psmc2
Name: proteasome 26S subunit, ATPase 2
RGD ID: 3428
Description: Enables TBP-class protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in P-body and cytosol. Predicted to be part of proteasome regulatory particle, base subcomplex. Orthologous to human PSMC2 (proteasome 26S subunit, ATPase 2); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 26S protease regulatory subunit 7; 26S proteasome AAA-ATPase subunit RPT1; 26S proteasome regulatory subunit 7; MSS1; proteasome (prosome, macropain) 26S subunit, ATPase 2; proteasome 26S subunit ATPase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8414,148,080 - 14,162,390 (-)NCBIGRCr8
mRatBN7.2413,255,850 - 13,270,160 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl413,255,856 - 13,270,185 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx418,401,118 - 18,415,400 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0414,215,883 - 14,230,158 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0412,586,755 - 12,601,037 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.049,867,132 - 9,881,383 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl49,867,101 - 9,881,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.049,868,269 - 9,882,520 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.448,704,100 - 8,718,351 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.148,704,099 - 8,718,351 (-)NCBI
Celera48,847,110 - 8,861,246 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Psmc2RatNorman-Roberts syndrome  ISOPSMC2 (Homo sapiens)8554872ClinVar Annotator: match by term: Norman-Roberts syndromeClinVarPMID:10973257 more ...
Psmc2Ratpleomorphic xanthoastrocytoma  ISOPSMC2 (Homo sapiens)8554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Psmc2Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PSMC2 mRNA]CTDPMID:31150632
Psmc2Rat(1->4)-beta-D-glucan multiple interactionsISOPsmc2 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PSMC2 mRNACTDPMID:36331819
Psmc2Rat(S)-nicotine multiple interactionsISOPsmc2 (Mus musculus)6480464[Nicotine co-treated with 1-Methyl-4-phenyl-1 more ...CTDPMID:20230807
Psmc2Rat1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expressionISOPsmc2 (Mus musculus)64804641-Methyl-4-phenyl-1 more ...CTDPMID:20230807
Psmc2Rat1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactionsISOPsmc2 (Mus musculus)6480464[Nicotine co-treated with 1-Methyl-4-phenyl-1 more ...CTDPMID:20230807
Psmc2Rat17alpha-ethynylestradiol increases expressionISOPsmc2 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of PSMC2 mRNACTDPMID:17942748
Psmc2Rat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of PSMC2 mRNACTDPMID:29097150
Psmc2Rat17alpha-ethynylestradiol multiple interactionsISOPsmc2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PSMC2 mRNACTDPMID:17942748
Psmc2Rat17alpha-ethynylestradiol affects expressionISOPsmc2 (Mus musculus)6480464Ethinyl Estradiol affects the expression of PSMC2 mRNACTDPMID:17555576
Psmc2Rat17beta-estradiol increases expressionISOPsmc2 (Mus musculus)6480464Estradiol results in increased expression of PSMC2 mRNACTDPMID:39298647
Psmc2Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactionsISOPSMC2 (Homo sapiens)6480464Metribolone promotes the reaction [NDRG1 protein binds to PSMC2 protein]CTDPMID:17220478
Psmc2Rat1H-pyrazole increases expressionISOPsmc2 (Mus musculus)6480464pyrazole results in increased expression of PSMC2 mRNACTDPMID:17945193
Psmc2Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOPsmc2 (Mus musculus)64804642 more ...CTDPMID:30294300
Psmc2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPsmc2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PSMC2 mRNACTDPMID:17942748
Psmc2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPsmc2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PSMC2 mRNACTDPMID:21570461
Psmc2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPsmc2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of PSMC2 mRNACTDPMID:17942748 and PMID:19465110
Psmc2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PSMC2 mRNA and Tetrachlorodibenzodioxin results in increased expression of PSMC2 proteinCTDPMID:19201780 and PMID:26232522
Psmc2Rat2,6-dimethoxyphenol multiple interactionsISOPSMC2 (Homo sapiens)6480464[Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in decreased expression of and affects the localization of PSMC2 proteinCTDPMID:38598786
Psmc2Rat2-amino-14,16-dimethyloctadecan-3-ol decreases expressionISOPSMC2 (Homo sapiens)64804642-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of PSMC2 proteinCTDPMID:32044396
Psmc2Rat2-bromohexadecanoic acid multiple interactionsISOPSMC2 (Homo sapiens)64804642-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of PSMC2 protein]CTDPMID:38195004

1 to 20 of 141 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Psmc2Ratpositive regulation of proteasomal protein catabolic process involved_inIEAGO:00364021600115GO_REF:0000108GOCGO_REF:0000108
Psmc2Ratproteasome-mediated ubiquitin-dependent protein catabolic process involved_inIBAFB:FBgn0015282 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Psmc2Ratubiquitin-dependent protein catabolic process involved_inIEAUniProtKB:P35998 and ensembl:ENSP000002926441600115GO_REF:0000107EnsemblGO_REF:0000107
Psmc2Ratubiquitin-dependent protein catabolic process involved_inISOPSMC2 (Homo sapiens)1624291 PMID:9295362RGDPMID:9295362

Cellular Component
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Psmc2Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Psmc2Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Psmc2Ratcytoplasmic ribonucleoprotein granule located_inIEAUniProtKB:A0A140VK70 and ensembl:ENSP000002926441600115GO_REF:0000107EnsemblGO_REF:0000107
Psmc2Ratcytoplasmic ribonucleoprotein granule located_inISOPSMC2 (Homo sapiens) and UniProtKB:P35998-11624291 RGDGO_REF:0000052
Psmc2Ratcytoplasmic ribonucleoprotein granule located_inIEAUniProtKB:P35998 and ensembl:ENSP000002926441600115GO_REF:0000107EnsemblGO_REF:0000107
Psmc2Ratcytosol located_inISOPSMC2 (Homo sapiens) and UniProtKB:P35998-11624291 RGDGO_REF:0000052
Psmc2Ratcytosol located_inIEAUniProtKB:A0A140VK70 and ensembl:ENSP000002926441600115GO_REF:0000107EnsemblGO_REF:0000107
Psmc2Ratcytosol located_inIEAUniProtKB:P35998 and ensembl:ENSP000002926441600115GO_REF:0000107EnsemblGO_REF:0000107
Psmc2RatP-body located_inISSUniProtKB:P464711600115GO_REF:0000024UniProtGO_REF:0000024
Psmc2RatP-body located_inIEAUniProtKB:P46471 and ensembl:ENSMUSP000000307691600115GO_REF:0000107EnsemblGO_REF:0000107
Psmc2RatP-body located_inISOPsmc2 (Mus musculus)1624291 PMID:22078707RGDPMID:22078707
Psmc2Ratproteasome accessory complex part_ofISOPsmc2 (Mus musculus)1624291 PMID:16857966RGDPMID:16857966
Psmc2Ratproteasome accessory complex part_ofIEAUniProtKB:P46471 and ensembl:ENSMUSP000000307691600115GO_REF:0000107EnsemblGO_REF:0000107
Psmc2Ratproteasome accessory complex part_ofISSUniProtKB:P464711600115GO_REF:0000024UniProtGO_REF:0000024
Psmc2Ratproteasome complex part_ofISOPSMC2 (Homo sapiens)1624291 PMID:17323924 more ...RGDPMID:17323924 more ...
Psmc2Ratproteasome complex part_ofIEAUniProtKB-KW:KW-06471600115GO_REF:0000043UniProtGO_REF:0000043
Psmc2Ratproteasome complex part_ofIEAUniProtKB:P35998 and ensembl:ENSP000002926441600115GO_REF:0000107EnsemblGO_REF:0000107
Psmc2Ratproteasome regulatory particle, base subcomplex part_ofIBAFB:FBgn0015282 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 18 of 18 rows

Molecular Function
1 to 11 of 11 rows

  
1 to 11 of 11 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Psmc2Ratubiquitin/proteasome degradation pathway  IEA 6907045 KEGGrno:03050

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#
Reference Title
Reference Citation
1. Activity-dependent dynamics and sequestration of proteasomes in dendritic spines. Bingol B and Schuman EM, Nature. 2006 Jun 29;441(7097):1144-8.
2. Participation of the 26S proteasome in the regulation of progesterone receptor concentrations in the rat brain. Camacho-Arroyo I, etal., Neuroendocrinology 2002 Nov;76(5):267-71.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Structures of the rat proteasomal ATPases: determination of highly conserved structural motifs and rules for their spacing. Makino Y, etal., Biochem Biophys Res Commun 1996 Mar 27;220(3):1049-54.
6. Multiple mammalian proteasomal ATPases, but not proteasome itself, are associated with TATA-binding protein and a novel transcriptional activator, TIP120. Makino Y, etal., Genes Cells. 1999 Sep;4(9):529-39.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13. Tissue and cell distribution of a mammalian proteasomal ATPase, MSS1, and its complex formation with the basal transcription factors. Yanagi S, etal., Biochem Biophys Res Commun. 2000 Dec 20;279(2):568-73.
1 to 13 of 13 rows
PMID:9295362   PMID:9533861   PMID:9688553   PMID:16210410   PMID:16857966   PMID:17323924   PMID:18419753   PMID:19638347   PMID:19946888   PMID:21630459   PMID:22078707   PMID:22871113  
PMID:30053369   PMID:31904090   PMID:33450132  



Psmc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8414,148,080 - 14,162,390 (-)NCBIGRCr8
mRatBN7.2413,255,850 - 13,270,160 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl413,255,856 - 13,270,185 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx418,401,118 - 18,415,400 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0414,215,883 - 14,230,158 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0412,586,755 - 12,601,037 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.049,867,132 - 9,881,383 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl49,867,101 - 9,881,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.049,868,269 - 9,882,520 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.448,704,100 - 8,718,351 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.148,704,099 - 8,718,351 (-)NCBI
Celera48,847,110 - 8,861,246 (-)NCBICelera
Cytogenetic Map4q11NCBI
PSMC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387103,347,524 - 103,369,395 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7103,328,570 - 103,370,346 (+)EnsemblGRCh38hg38GRCh38
GRCh377102,987,971 - 103,009,842 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367102,775,325 - 102,795,892 (+)NCBINCBI36Build 36hg18NCBI36
Build 347102,582,039 - 102,602,606NCBI
Celera797,795,300 - 97,815,873 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef797,350,323 - 97,372,344 (+)NCBIHuRef
CHM1_17102,920,963 - 102,943,153 (+)NCBICHM1_1
T2T-CHM13v2.07104,661,962 - 104,683,844 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27102,348,337 - 102,370,208 (+)NCBI
Psmc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39521,990,273 - 22,008,785 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl521,990,281 - 22,008,785 (+)EnsemblGRCm39 Ensembl
GRCm38521,785,275 - 21,803,787 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl521,785,283 - 21,803,787 (+)EnsemblGRCm38mm10GRCm38
MGSCv37521,291,101 - 21,309,602 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36521,297,107 - 21,315,608 (+)NCBIMGSCv36mm8
Celera518,756,208 - 18,774,395 (+)NCBICelera
Cytogenetic Map5A3NCBI
cM Map59.97NCBI
Psmc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554108,341,065 - 8,356,148 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554108,341,218 - 8,355,515 (+)NCBIChiLan1.0ChiLan1.0
PSMC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26140,201,706 - 140,227,300 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17188,473,396 - 188,497,270 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0795,338,743 - 95,359,353 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17108,083,019 - 108,103,595 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7108,083,203 - 108,103,494 (+)Ensemblpanpan1.1panPan2
PSMC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11816,845,593 - 16,859,010 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1816,845,594 - 16,858,911 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1816,488,537 - 16,501,956 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01817,136,145 - 17,149,599 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1817,136,146 - 17,149,526 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11816,900,975 - 16,914,588 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01816,839,559 - 16,853,208 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01817,107,769 - 17,121,439 (-)NCBIUU_Cfam_GSD_1.0
Psmc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511859,026,969 - 59,043,987 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647920,148,632 - 20,168,130 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647920,150,738 - 20,167,765 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSMC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9103,362,599 - 103,376,343 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19103,362,684 - 103,376,048 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29113,971,194 - 113,984,560 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PSMC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12172,323,691 - 72,341,647 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2172,323,803 - 72,341,488 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604231,660,968 - 31,679,446 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psmc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473926,001,871 - 26,016,040 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473926,001,871 - 26,015,633 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Psmc2
160 total Variants

Predicted Target Of
Summary Value
Count of predictions:53
Count of miRNA genes:49
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000016450
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 30 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat

1 to 10 of 30 rows
RH142410  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2413,255,880 - 13,256,039 (+)MAPPERmRatBN7.2
Rnor_6.049,867,162 - 9,867,320NCBIRnor6.0
Rnor_5.049,868,299 - 9,868,457UniSTSRnor5.0
RGSC_v3.448,704,130 - 8,704,288UniSTSRGSC3.4
Celera48,847,140 - 8,847,298UniSTS
Cytogenetic Map4q11UniSTS
RH142567  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2413,263,934 - 13,264,045 (+)MAPPERmRatBN7.2
Rnor_6.049,875,216 - 9,875,326NCBIRnor6.0
Rnor_5.049,876,353 - 9,876,463UniSTSRnor5.0
RGSC_v3.448,712,184 - 8,712,294UniSTSRGSC3.4
Celera48,855,194 - 8,855,304UniSTS
Cytogenetic Map4q11UniSTS
RH140841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2413,255,879 - 13,256,072 (+)MAPPERmRatBN7.2
Rnor_6.049,867,161 - 9,867,353NCBIRnor6.0
Rnor_5.049,868,298 - 9,868,490UniSTSRnor5.0
RGSC_v3.448,704,129 - 8,704,321UniSTSRGSC3.4
Celera48,847,139 - 8,847,331UniSTS
RH 3.4 Map440.0UniSTS
Cytogenetic Map4q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 16 of 16 rows
RefSeq Transcripts NM_033236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC141152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC061542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D50694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 16 of 16 rows

Ensembl Acc Id: ENSRNOT00000016450   ⟹   ENSRNOP00000016450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl413,255,856 - 13,270,185 (-)Ensembl
Rnor_6.0 Ensembl49,867,101 - 9,881,484 (-)Ensembl
RefSeq Acc Id: NM_033236   ⟹   NP_150239
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8414,148,080 - 14,162,390 (-)NCBI
mRatBN7.2413,255,850 - 13,270,160 (-)NCBI
Rnor_6.049,867,132 - 9,881,383 (-)NCBI
Rnor_5.049,868,269 - 9,882,520 (-)NCBI
RGSC_v3.448,704,100 - 8,718,351 (-)RGD
Celera48,847,110 - 8,861,246 (-)RGD
Sequence:
1 to 10 of 10 rows
Protein RefSeqs NP_150239 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC53589 (Get FASTA)   NCBI Sequence Viewer  
  AAH61542 (Get FASTA)   NCBI Sequence Viewer  
  BAA09339 (Get FASTA)   NCBI Sequence Viewer  
  EDL99410 (Get FASTA)   NCBI Sequence Viewer  
  EDL99411 (Get FASTA)   NCBI Sequence Viewer  
  EDL99412 (Get FASTA)   NCBI Sequence Viewer  
  EDL99413 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016450
GenBank Protein Q63347 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_150239   ⟸   NM_033236
- UniProtKB: Q6P7R9 (UniProtKB/Swiss-Prot),   Q63347 (UniProtKB/Swiss-Prot),   Q62690 (UniProtKB/Swiss-Prot),   G3V7L6 (UniProtKB/TrEMBL),   A6K5A1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016450   ⟸   ENSRNOT00000016450
Name Modeler Protein Id AA Range Protein Structure
AF-Q63347-F1-model_v2 AlphaFold Q63347 1-433 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13692805
Promoter ID:EPDNEW_R3329
Type:multiple initiation site
Name:Psmc2_1
Description:proteasome 26S subunit, ATPase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.049,881,413 - 9,881,473EPDNEW


1 to 38 of 38 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-45988 BioCyc
Ensembl Genes ENSRNOG00000012026 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000016450 ENTREZGENE
Gene3D-CATH 1.10.8.60 UniProtKB/Swiss-Prot
  2.40.50.140 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6918933 IMAGE-MGC_LOAD
InterPro 26S_Proteasome_ATPase UniProtKB/Swiss-Prot
  AAA+_ATPase UniProtKB/Swiss-Prot
  AAA_lid_3 UniProtKB/Swiss-Prot
  ATPase_AAA_core UniProtKB/Swiss-Prot
  ATPase_AAA_CS UniProtKB/Swiss-Prot
  NA-bd_OB-fold UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  PRS7-like_OB UniProtKB/Swiss-Prot
KEGG Report rno:25581 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72754 IMAGE-MGC_LOAD
NCBI Gene 25581 ENTREZGENE
PANTHER 26S PROTEASOME REGULATORY SUBUNIT UniProtKB/Swiss-Prot
Pfam AAA UniProtKB/Swiss-Prot
  AAA_lid_3 UniProtKB/Swiss-Prot
  PRS7_OB UniProtKB/Swiss-Prot
PhenoGen Psmc2 PhenoGen
PROSITE AAA UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012026 RatGTEx
SMART AAA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A6K5A1 ENTREZGENE, UniProtKB/TrEMBL
  A6K5A2_RAT UniProtKB/TrEMBL
  A6K5A3_RAT UniProtKB/TrEMBL
  A6K5A4_RAT UniProtKB/TrEMBL
  G3V7L6 ENTREZGENE, UniProtKB/TrEMBL
  PRS7_RAT UniProtKB/Swiss-Prot
  Q62690 ENTREZGENE
  Q63347 ENTREZGENE
  Q6P7R9 ENTREZGENE
UniProt Secondary Q62690 UniProtKB/Swiss-Prot
  Q6P7R9 UniProtKB/Swiss-Prot
1 to 38 of 38 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-19 Psmc2  proteasome 26S subunit, ATPase 2  Psmc2  proteasome (prosome, macropain) 26S subunit, ATPase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Psmc2  Proteasome (prosome, macropain) 26S subunit, ATPase      Symbol and Name status set to approved 70586 APPROVED