Pgm1 (phosphoglucomutase 1) - Rat Genome Database

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Gene: Pgm1 (phosphoglucomutase 1) Rattus norvegicus
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Symbol: Pgm1
Name: phosphoglucomutase 1
RGD ID: 3316
Description: Enables phosphoglucomutase activity. Involved in cellular response to magnetism and glucose metabolic process. Located in Z disc. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation It; endometrial cancer; and teratoma. Orthologous to human PGM1 (phosphoglucomutase 1); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; fructose-1,6-bisphosphatase deficiency pathway; galactokinase deficiency pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glucose phosphomutase 1; PGM 1; phosphoglucomutase-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85119,710,734 - 119,770,159 (+)NCBIGRCr8
mRatBN7.25114,595,298 - 114,654,728 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5114,595,293 - 114,654,728 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5117,151,682 - 117,211,109 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05118,877,005 - 118,936,428 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05118,939,539 - 118,998,971 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05118,743,632 - 118,803,055 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5118,743,632 - 118,803,055 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05122,648,579 - 122,708,212 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45120,595,650 - 120,655,915 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5113,142,712 - 113,202,105 (+)NCBICelera
RH 3.4 Map5 RGD
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
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Qualifier
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Original Reference(s)
Pgm1Ratendometrial cancer  ISOPGM1 (Homo sapiens)2299870 RGD 
Pgm1Ratteratoma  ISOPGM1 (Homo sapiens)2299871 RGD 
Object Symbol
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Original Reference(s)
Pgm1Ratcongenital disorder of glycosylation  ISOPGM1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Pgm1Ratcongenital disorder of glycosylation It  ISOPGM1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16199547 more ...
Pgm1RatCraniosynostosis Syndrome, Autosomal Recessive  ISOPGM1 (Homo sapiens)8554872ClinVar Annotator: match by term: Craniosynostosis syndromeClinVarPMID:25741868
Pgm1Ratgenetic disease  ISOPGM1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:24499211 more ...
Pgm1Ratintellectual disability  ISOPGM1 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disability and severeClinVarPMID:25741868
Object Symbol
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Original Reference(s)
Pgm1RatChemical and Drug Induced Liver Injury  ISOPGM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25231249
Pgm1RatColorectal Neoplasms  ISOPGM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25944804
Pgm1Ratcongenital disorder of glycosylation It  ISOPGM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Pgm1RatMyocardial Ischemia  ISOPGM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16214533
Object Symbol
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Original Reference(s)
Pgm1Ratcongenital disorder of glycosylation It  ISOPGM1 (Homo sapiens)7240710 OMIM 

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Original Reference(s)
Pgm1Rat(-)-demecolcine decreases expressionISOPGM1 (Homo sapiens)6480464Demecolcine results in decreased expression of PGM1 mRNACTDPMID:23649840
Pgm1Rat(1->4)-beta-D-glucan multiple interactionsISOPgm1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PGM1 mRNACTDPMID:36331819
Pgm1Rat1,2-dimethylhydrazine decreases expressionISOPgm1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of PGM1 mRNACTDPMID:22206623
Pgm1Rat17alpha-ethynylestradiol increases expressionISOPgm1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of PGM1 mRNACTDPMID:17942748
Pgm1Rat17alpha-ethynylestradiol multiple interactionsISOPgm1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PGM1 mRNACTDPMID:17942748
Pgm1Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of PGM1 proteinCTDPMID:32145629
Pgm1Rat17beta-estradiol decreases expressionISOPgm1 (Mus musculus)6480464Estradiol results in decreased expression of PGM1 mRNACTDPMID:39298647
Pgm1Rat1H-pyrazole increases expressionISOPgm1 (Mus musculus)6480464pyrazole results in increased expression of PGM1 mRNACTDPMID:17945193
Pgm1Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOPgm1 (Mus musculus)64804642 more ...CTDPMID:30294300
Pgm1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPgm1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PGM1 mRNACTDPMID:17942748
Pgm1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPgm1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of PGM1 mRNACTDPMID:27562557
Pgm1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPGM1 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of PGM1 mRNACTDPMID:23152189
Pgm1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPGM1 (Homo sapiens)64804642-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PGM1 mRNA] and alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PGM1 mRNA]CTDPMID:23152189
Pgm1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of PGM1 mRNACTDPMID:22298810
Pgm1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PGM1 mRNACTDPMID:18796159 more ...
Pgm1Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOPgm1 (Mus musculus)64804642 more ...CTDPMID:38648751
Pgm1Rat2,6-dimethoxyphenol multiple interactionsISOPGM1 (Homo sapiens)6480464[pyrogallol 1 and 3-dimethyl ether co-treated with Furaldehyde] results in increased expression of and affects the localization of PGM1 proteinCTDPMID:38598786
Pgm1Rat2-hydroxypropanoic acid decreases expressionISOPGM1 (Homo sapiens)6480464Lactic Acid results in decreased expression of PGM1 mRNACTDPMID:30851411
Pgm1Rat2-methoxyethanol decreases expressionEXP 6480464methyl cellosolve results in decreased expression of PGM1 proteinCTDPMID:15928459
Pgm1Rat4,4'-sulfonyldiphenol increases expressionISOPgm1 (Mus musculus)6480464bisphenol S results in increased expression of PGM1 mRNACTDPMID:39298647

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Biological Process
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Cellular Component

  
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Original Reference(s)
Pgm1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Pgm1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Pgm1Ratcytosol is_active_inIBAPANTHER:PTN000501426 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pgm1RatZ disc  IDA 11069392 RGD 

Molecular Function
1 to 17 of 17 rows

  
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Original Reference(s)
Pgm1Ratintramolecular phosphotransferase activity enablesIEAInterPro:IPR005841 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Pgm1Ratisomerase activity enablesIEAUniProtKB-KW:KW-04131600115GO_REF:0000043UniProtGO_REF:0000043
Pgm1Ratmagnesium ion binding enablesIEAUniProtKB:P36871 and ensembl:ENSP000003601251600115GO_REF:0000107EnsemblGO_REF:0000107
Pgm1Ratmagnesium ion binding enablesIEAInterPro:IPR0160661600115GO_REF:0000002InterProGO_REF:0000002
Pgm1Ratmagnesium ion binding enablesISOPGM1 (Homo sapiens)1624291 PMID:26972339RGDPMID:26972339
Pgm1Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Pgm1Ratphosphoglucomutase activity enablesISOPGM1 (Homo sapiens)1624291 PMID:1530890 more ...RGDPMID:1530890 more ...
Pgm1Ratphosphoglucomutase activity enablesIEAUniProtKB:Q9D0F9 and ensembl:ENSMUSP000000612271600115GO_REF:0000107EnsemblGO_REF:0000107
Pgm1Ratphosphoglucomutase activity enablesIEARHEA:235361600115GO_REF:0000116RHEAGO_REF:0000116
Pgm1Ratphosphoglucomutase activity enablesIBAFB:FBgn0003076 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pgm1Ratphosphoglucomutase activity enablesIEAEC:5.4.2.21600115GO_REF:0000003UniProtGO_REF:0000003
Pgm1Ratphosphoglucomutase activity enablesISOPgm1 (Mus musculus)1624291 PMID:31077402 more ...RGDPMID:31077402 more ...
Pgm1Ratphosphoglucomutase activity enablesIEAInterPro:IPR0452441600115GO_REF:0000002InterProGO_REF:0000002
Pgm1Ratphosphoglucomutase activity enablesIDA 633702PMID:8224913UniProt 
Pgm1Ratphosphoglucomutase activity enablesIEAUniProtKB:P36871 and ensembl:ENSP000003601251600115GO_REF:0000107EnsemblGO_REF:0000107
Pgm1Ratprotein binding  IPILdb3 (Rattus norvegicus)11069392 RGD 
Pgm1Ratprotein binding enablesISOPGM1 (Homo sapiens)1624291UniProtKB:Q9BSI4 and PMID:21044950RGDPMID:21044950
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RGD Manual Annotations


  
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Original Reference(s)
Pgm1Ratglycogen biosynthetic pathway   ISOPGM1 (Homo sapiens)2304188 RGD 
Pgm1Ratglycogen degradation pathway   ISOPGM1 (Homo sapiens)2304188 RGD 

Imported Annotations - SMPDB

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Original Reference(s)
Pgm1Ratcongenital sucrase-isomaltase deficiency pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00557
Pgm1Ratfructose-1,6-bisphosphatase deficiency pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00562
Pgm1Ratgalactokinase deficiency pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00495
Pgm1Ratgalactose metabolic pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00043
Pgm1Ratgalactosemia pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00182
Pgm1RatGALE deficiency pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00496
Pgm1Ratgluconeogenesis pathway   ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00128
Pgm1Ratglycogen storage disease type Ia pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00374
Pgm1Ratglycogen storage disease type Ia pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00581
Pgm1Ratglycogen storage disease type Ib pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00573
Pgm1Ratglycogen storage disease type III pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00553
Pgm1Ratglycogen storage disease type IV pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00554
Pgm1Ratglycogen storage disease type VI pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00555
Pgm1Ratnucleotide sugar metabolic pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00010
Pgm1Ratpentose phosphate pathway   ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00031
Pgm1Ratphosphoenolpyruvate carboxykinase deficiency pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00560
Pgm1Ratribose 5-phosphate isomerase deficiency pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00519
Pgm1Ratstarch and sucrose metabolic pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00058
Pgm1Rattransaldolase deficiency pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00520
Pgm1Rattriosephosphate isomerase deficiency pathway  ISOPGM1 (Homo sapiens)10402751 SMPDBSMP:00563
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Imported Annotations - KEGG (archival)

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Original Reference(s)
Pgm1Ratamino sugar metabolic pathway  IEA 6907045 KEGGrno:00520
Pgm1Ratgalactose metabolic pathway  IEA 6907045 KEGGrno:00052
Pgm1Ratgluconeogenesis pathway   IEA 6907045 KEGGrno:00010
Pgm1Ratglycolysis pathway   IEA 6907045 KEGGrno:00010
Pgm1Ratglycolysis/gluconeogenesis pathway  IEA 6907045 KEGGrno:00010
Pgm1Ratnucleotide sugar metabolic pathway  IEA 6907045 KEGGrno:00520
Pgm1Ratpentose phosphate pathway   IEA 6907045 KEGGrno:00030
Pgm1Ratpurine metabolic pathway  IEA 6907045 KEGGrno:00230
Pgm1Ratstarch and sucrose metabolic pathway  IEA 6907045 KEGGrno:00500
1 to 9 of 9 rows

Imported Annotations - PID (archival)

Object Symbol
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Original Reference(s)
Pgm1Rathypoxia inducible factor pathway   ISOPGM1 (Homo sapiens)6484113 PIDPID:200202

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#
Reference Title
Reference Citation
1. Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy. Arimura T, etal., Cardiovasc Res. 2009 Jul 1;83(1):80-8. doi: 10.1093/cvr/cvp119. Epub 2009 Apr 17.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
6. Gene loss in human teratomas. Linder D, Proc Natl Acad Sci U S A. 1969 Jul;63(3):699-704.
7. Isoenzymes of hexokinase, 6-phosphogluconate dehydrogenase, phosphoglucomutase and lactate dehydrogenase in uterine cancer. Marshall MJ, etal., Br J Cancer. 1979 Sep;40(3):380-90.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. Long-term alcohol intake enhances ADP-ribosylation of the multifunctional enzyme, phosphoglucomutase, in rat liver. Nomura F, etal., Hepatology 1996 Nov;24(5):1246-9.
11. Isolation and immunohistochemical localization of a chondroitin sulfate proteoglycan from adult rat brain. Normand G, etal., J Neurochem. 1988 Sep;51(3):665-76.
12. Differentiation of chromaffin cells elicited by ELF MF modifies gene expression pattern. Olivares-Banuelos T, etal., Cell Biol Int. 2004;28(4):273-9.
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
16. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
17. GOA pipeline RGD automated data pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Comprehensive gene review and curation RGD comprehensive gene curation
1 to 20 of 22 rows
PMID:1530890   PMID:1840235   PMID:4646763   PMID:5392465   PMID:7323947   PMID:7444718   PMID:7665162   PMID:12477932   PMID:19056867   PMID:23533145   PMID:25288802   PMID:26945066  
PMID:26972339  



Pgm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85119,710,734 - 119,770,159 (+)NCBIGRCr8
mRatBN7.25114,595,298 - 114,654,728 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5114,595,293 - 114,654,728 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5117,151,682 - 117,211,109 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05118,877,005 - 118,936,428 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05118,939,539 - 118,998,971 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05118,743,632 - 118,803,055 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5118,743,632 - 118,803,055 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05122,648,579 - 122,708,212 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45120,595,650 - 120,655,915 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5113,142,712 - 113,202,105 (+)NCBICelera
RH 3.4 Map5 RGD
Cytogenetic Map5q33NCBI
PGM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,593,411 - 63,660,245 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl163,593,411 - 63,660,245 (+)EnsemblGRCh38hg38GRCh38
GRCh37164,059,082 - 64,125,916 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,831,535 - 63,898,504 (+)NCBINCBI36Build 36hg18NCBI36
Build 34163,770,967 - 63,837,935NCBI
Celera162,348,856 - 62,415,793 (+)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef162,166,918 - 62,233,884 (+)NCBIHuRef
CHM1_1164,174,737 - 64,241,622 (+)NCBICHM1_1
T2T-CHM13v2.0163,469,205 - 63,536,042 (+)NCBIT2T-CHM13v2.0
Pgm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39499,786,648 - 99,844,491 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl499,786,611 - 99,844,491 (+)EnsemblGRCm39 Ensembl
GRCm38499,929,451 - 99,987,294 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl499,929,414 - 99,987,294 (+)EnsemblGRCm38mm10GRCm38
MGSCv37499,602,056 - 99,659,899 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36499,427,439 - 99,485,223 (+)NCBIMGSCv36mm8
Celera498,273,961 - 98,332,209 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map445.71NCBI
Pgm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542326,408,595 - 26,437,527 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542326,408,775 - 26,437,527 (-)NCBIChiLan1.0ChiLan1.0
PGM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21163,193,482 - 163,262,694 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11162,344,100 - 162,411,352 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0162,849,451 - 62,916,359 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1164,658,599 - 64,725,496 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,658,599 - 64,725,496 (+)Ensemblpanpan1.1panPan2
PGM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1546,444,433 - 46,577,621 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl546,515,295 - 46,577,622 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha546,505,433 - 46,638,431 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0546,624,512 - 46,757,954 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl546,672,266 - 46,757,997 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1546,586,542 - 46,719,720 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0546,532,568 - 46,666,112 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0546,790,338 - 46,923,562 (-)NCBIUU_Cfam_GSD_1.0
Pgm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505876,845,424 - 76,905,846 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366921,160,623 - 1,221,746 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366921,160,836 - 1,221,270 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6148,851,183 - 148,994,952 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16148,851,183 - 148,918,891 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26137,171,270 - 137,233,581 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PGM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12069,391,487 - 69,495,156 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2069,428,996 - 69,466,191 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603347,968,869 - 48,035,370 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474230,542,448 - 30,592,162 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474230,543,161 - 30,592,117 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pgm1
457 total Variants

Predicted Target Of
Summary Value
Count of predictions:72
Count of miRNA genes:69
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000013785
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 46 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
7794743Bp373Blood pressure QTL 3730.0058arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5112175546116047089Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat

1 to 10 of 46 rows
D5Rhm1   No map positions available.
D5Rhm2  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85119,774,989 - 119,775,157 (+)Marker Load Pipeline
mRatBN7.25114,659,557 - 114,659,726 (+)MAPPERmRatBN7.2
Rnor_6.05118,807,885 - 118,808,053NCBIRnor6.0
Rnor_5.05122,713,042 - 122,713,210UniSTSRnor5.0
RGSC_v3.45120,660,745 - 120,660,913UniSTSRGSC3.4
Celera5113,206,935 - 113,207,103UniSTS
Cytogenetic Map5q33UniSTS
BF386789  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25114,594,795 - 114,594,990 (+)MAPPERmRatBN7.2
Rnor_6.05118,743,130 - 118,743,324NCBIRnor6.0
Rnor_5.05122,648,077 - 122,648,271UniSTSRnor5.0
RGSC_v3.45120,595,148 - 120,595,342UniSTSRGSC3.4
Celera5113,142,210 - 113,142,404UniSTS
RH 3.4 Map5791.3UniSTS
Cytogenetic Map5q33UniSTS
RH142295  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85119,742,627 - 119,743,215 (+)Marker Load Pipeline
mRatBN7.25114,627,194 - 114,627,782 (+)MAPPERmRatBN7.2
Rnor_6.05118,775,524 - 118,776,111NCBIRnor6.0
Rnor_5.05122,680,510 - 122,681,097UniSTSRnor5.0
RGSC_v3.45120,628,325 - 120,628,912UniSTSRGSC3.4
Celera5113,174,572 - 113,175,159UniSTS
RH 3.4 Map5791.3UniSTS
Cytogenetic Map5q33UniSTS
RH141738  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25114,654,451 - 114,654,660 (+)MAPPERmRatBN7.2
Rnor_6.05118,802,779 - 118,802,987NCBIRnor6.0
Rnor_5.05122,707,936 - 122,708,144UniSTSRnor5.0
RGSC_v3.45120,655,639 - 120,655,847UniSTSRGSC3.4
Celera5113,201,829 - 113,202,037UniSTS
RH 3.4 Map5793.1UniSTS
Cytogenetic Map5q33UniSTS
ha2531  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22136,958,572 - 136,959,506 (+)MAPPERmRatBN7.2
mRatBN7.25114,606,869 - 114,607,662 (+)MAPPERmRatBN7.2
Rnor_6.05118,755,205 - 118,755,997NCBIRnor6.0
Rnor_6.02142,094,995 - 142,095,928NCBIRnor6.0
Rnor_5.05122,660,152 - 122,660,944UniSTSRnor5.0
Rnor_5.02161,781,593 - 161,782,526UniSTSRnor5.0
RGSC_v3.42141,796,704 - 141,797,637UniSTSRGSC3.4
RGSC_v3.45120,607,223 - 120,608,015UniSTSRGSC3.4
Celera5113,154,160 - 113,154,952UniSTS
Celera2131,456,163 - 131,457,096UniSTS
Cytogenetic Map5q33UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000013785   ⟹   ENSRNOP00000013785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5114,595,293 - 114,654,727 (+)Ensembl
Rnor_6.0 Ensembl5118,743,632 - 118,803,055 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103908   ⟹   ENSRNOP00000097832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5114,619,959 - 114,654,728 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118798   ⟹   ENSRNOP00000081014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5114,621,360 - 114,654,728 (+)Ensembl
RefSeq Acc Id: NM_017033   ⟹   NP_058729
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85119,710,734 - 119,770,159 (+)NCBI
mRatBN7.25114,595,298 - 114,654,728 (+)NCBI
Rnor_6.05118,743,632 - 118,803,055 (+)NCBI
Rnor_5.05122,648,579 - 122,708,212 (+)NCBI
RGSC_v3.45120,595,650 - 120,655,915 (+)RGD
Celera5113,142,712 - 113,202,105 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238442   ⟹   XP_006238504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85119,736,187 - 119,770,159 (+)NCBI
mRatBN7.25114,620,858 - 114,654,728 (+)NCBI
Rnor_6.05118,769,155 - 118,803,055 (+)NCBI
Rnor_5.05122,648,579 - 122,708,212 (+)NCBI
Sequence:
RefSeq Acc Id: NP_058729   ⟸   NM_017033
- UniProtKB: P38652 (UniProtKB/Swiss-Prot),   Q499Q4 (UniProtKB/TrEMBL),   A6JRM5 (UniProtKB/TrEMBL),   F7F2L9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238504   ⟸   XM_006238442
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000013785   ⟸   ENSRNOT00000013785
Ensembl Acc Id: ENSRNOP00000097832   ⟸   ENSRNOT00000103908
Ensembl Acc Id: ENSRNOP00000081014   ⟸   ENSRNOT00000118798
Name Modeler Protein Id AA Range Protein Structure
AF-P38652-F1-model_v2 AlphaFold P38652 1-562 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693856
Promoter ID:EPDNEW_R4381
Type:initiation region
Name:Pgm1_1
Description:phosphoglucomutase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05118,743,600 - 118,743,660EPDNEW


1 to 40 of 42 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-40563 BioCyc
BioCyc Pathway PWY-5941 [glycogen degradation II] BioCyc
  PWY-7343 [UDP-alpha-D-glucose biosynthesis] BioCyc
BioCyc Pathway Image PWY-5941 BioCyc
  PWY-7343 BioCyc
Ensembl Genes ENSRNOG00000009889 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000013785 ENTREZGENE
  ENSRNOT00000103908 ENTREZGENE
Gene3D-CATH Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 UniProtKB/Swiss-Prot
  Alpha-D-phosphohexomutase, C-terminal domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7937943 IMAGE-MGC_LOAD
  IMAGE:8367784 IMAGE-MGC_LOAD
InterPro A-D-PHexomutase_a/b/a-I UniProtKB/Swiss-Prot
  A-D-PHexomutase_a/b/a-I/II/III UniProtKB/Swiss-Prot
  A-D-PHexomutase_a/b/a-II UniProtKB/Swiss-Prot
  A-D-PHexomutase_a/b/a-III UniProtKB/Swiss-Prot
  A-D-PHexomutase_C_sf UniProtKB/Swiss-Prot
  A-D-PHexomutase_CS UniProtKB/Swiss-Prot
  Alpha-D-phosphohexomutase_SF UniProtKB/Swiss-Prot
  PGM UniProtKB/Swiss-Prot
MGC_CLONE MGC:124624 IMAGE-MGC_LOAD
  MGC:156500 IMAGE-MGC_LOAD
NCBI Gene 24645 ENTREZGENE
PANTHER PHOSPHOGLUCOMUTASE-1 UniProtKB/Swiss-Prot
  PTHR22573 UniProtKB/Swiss-Prot
Pfam PGM_PMM_I UniProtKB/Swiss-Prot
  PGM_PMM_II UniProtKB/Swiss-Prot
  PGM_PMM_III UniProtKB/Swiss-Prot
PhenoGen Pgm1 PhenoGen
PRINTS PGMPMM UniProtKB/Swiss-Prot
PROSITE PGM_PMM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009889 RatGTEx
Superfamily-SCOP SSF53738 UniProtKB/Swiss-Prot
  SSF55957 UniProtKB/Swiss-Prot
UniProt A0A8I5ZRI9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AV00 ENTREZGENE, UniProtKB/TrEMBL
  A1A5L2_RAT UniProtKB/TrEMBL
  A6JRM5 ENTREZGENE, UniProtKB/TrEMBL
  F7F2L9 ENTREZGENE, UniProtKB/TrEMBL
  P38652 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 40 of 42 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Pgm1  Phosphoglucomutase 1      Symbol and Name status set to approved 70586 APPROVED

Note Type Note Reference
gene_protein 58 kDa 724639
gene_regulation substrate for Ca2+/calmodulindependent protein kinase; ADP-ribosylation increased in liver by long-term alcohol intake 724639