Mras (muscle RAS oncogene homolog) - Rat Genome Database

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Gene: Mras (muscle RAS oncogene homolog) Rattus norvegicus
Analyze
Symbol: Mras
Name: muscle RAS oncogene homolog
RGD ID: 3111
Description: Predicted to enable GTP-dependent protein binding activity; GTPase activity; and guanyl ribonucleotide binding activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in endomembrane system and membrane. Predicted to be part of protein phosphatase type 1 complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 11. Orthologous to human MRAS (muscle RAS oncogene homolog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: muscle and microspikes RAS; ras-related protein M-Ras; ras-related protein R-Ras3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,823,374 - 108,886,104 (-)NCBIGRCr8
mRatBN7.2899,944,036 - 100,006,771 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,944,036 - 99,996,408 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8105,610,343 - 105,663,748 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08103,809,642 - 103,863,053 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08101,652,159 - 101,705,561 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08107,629,028 - 107,656,851 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8107,629,028 - 107,681,512 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08107,054,728 - 107,082,497 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48104,244,660 - 104,272,556 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18104,264,114 - 104,292,011 (-)NCBI
Celera899,345,811 - 99,373,539 (-)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MrasRatgenetic disease  ISOMRAS (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 more ...
MrasRatNoonan syndrome 11  ISOMRAS (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25252692 more ...
MrasRatRASopathy  ISOMRAS (Homo sapiens)8554872ClinVar Annotator: match by term: RASopathyClinVarPMID:25741868 more ...
MrasRatspermatogenic failure 57  ISOMRAS (Homo sapiens)8554872ClinVar Annotator: match by term: Male infertility with azoospermia or oligozoospermia due to single gene mutationClinVarPMID:29493581
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MrasRatcarotid artery disease  ISOMRAS (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19198612
MrasRatcoronary artery disease  ISOMRAS (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21378990 and PMID:35590109
MrasRatCoronary Disease  ISOMRAS (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28869590
MrasRattype 2 diabetes mellitus  ISOMRAS (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28869590
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MrasRatNoonan syndrome 11  ISOMRAS (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MrasRat1,2-dimethylhydrazine affects expressionISOMras (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of MRAS mRNACTDPMID:22206623
MrasRat15-acetyldeoxynivalenol increases expressionISOMRAS (Homo sapiens)648046415-acetyldeoxynivalenol results in increased expression of MRAS mRNACTDPMID:23792671
MrasRat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of MRAS mRNACTDPMID:15212814
MrasRat17alpha-ethynylestradiol multiple interactionsISOMras (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MRAS mRNACTDPMID:17942748
MrasRat17beta-estradiol multiple interactionsISOMRAS (Homo sapiens)6480464[Estradiol co-treated with Progesterone] results in increased expression of MRAS mRNA and [Estradiol co-treated with TGFB1 protein] results in increased expression of MRAS mRNACTDPMID:20660070 and PMID:30165855
MrasRat2,2',5,5'-tetrachlorobiphenyl increases expressionISOMRAS (Homo sapiens)64804642 more ...CTDPMID:21703328
MrasRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOMras (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of MRAS mRNACTDPMID:19933214
MrasRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of MRAS mRNACTDPMID:34747641
MrasRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of MRAS mRNACTDPMID:27913140
MrasRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOMras (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of MRAS mRNACTDPMID:21570461
MrasRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOMRAS (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of MRAS mRNACTDPMID:20106945 and PMID:21632981
MrasRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOMras (Mus musculus)6480464[Tetrachlorodibenzodioxin affects the methylation of MRAS intron] which results in decreased expression of MRAS mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MRAS mRNACTDPMID:17942748 and PMID:33017471
MrasRat2-hydroxypropanoic acid decreases expressionISOMRAS (Homo sapiens)6480464Lactic Acid results in decreased expression of MRAS mRNACTDPMID:30851411
MrasRat4,4'-diaminodiphenylmethane decreases expressionISOMras (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of MRAS mRNACTDPMID:18648102
MrasRat4,4'-sulfonyldiphenol decreases expressionISOMras (Mus musculus)6480464bisphenol S results in decreased expression of MRAS mRNACTDPMID:39298647
MrasRat5-fluorouracil affects expressionISOMRAS (Homo sapiens)6480464Fluorouracil affects the expression of MRAS mRNACTDPMID:16584549
MrasRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of MRAS mRNACTDPMID:30047161
MrasRat8-Br-cAMP increases expressionISOMRAS (Homo sapiens)64804648-Bromo Cyclic Adenosine Monophosphate results in increased expression of MRAS mRNACTDPMID:22079614
MrasRatacetamide increases expressionEXP 6480464acetamide results in increased expression of MRAS mRNACTDPMID:31881176
MrasRataflatoxin B1 increases methylationISOMRAS (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of MRAS geneCTDPMID:27153756

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Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MrasRatcellular response to leukemia inhibitory factor acts_upstream_of_or_withinISOMras (Mus musculus)1624291 PMID:20439489RGDPMID:20439489
MrasRatRas protein signal transduction involved_inISOMRAS (Homo sapiens)1624291 PMID:28289718RGDPMID:28289718
MrasRatsignal transduction involved_inIEAInterPro:IPR0208491600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MrasRatendomembrane system located_inIEAUniProtKB-SubCell:SL-01471600115GO_REF:0000044UniProtGO_REF:0000044
MrasRatmembrane located_inIEAInterPro:IPR0208491600115GO_REF:0000002InterProGO_REF:0000002
MrasRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
MrasRatplasma membrane is_active_inIBACGD:CAL0000184093 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MrasRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
MrasRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
MrasRatprotein phosphatase type 1 complex part_ofISOMRAS (Homo sapiens)1624291 PMID:35768504 more ...RGDPMID:35768504 more ...

Molecular Function
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Object Symbol
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Evidence
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Reference
Notes
Source
Original Reference(s)
MrasRatG protein activity enablesIEAEC:3.6.5.21600115GO_REF:0000003UniProtGO_REF:0000003
MrasRatGDP binding enablesIBAPANTHER:PTN000631348 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MrasRatGTP binding enablesIEAUniProtKB-KW:KW-03421600115GO_REF:0000043UniProtGO_REF:0000043
MrasRatGTP binding enablesIBAMGI:108053 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MrasRatGTP binding enablesIEAInterPro:IPR001806 more ...1600115GO_REF:0000002InterProGO_REF:0000002
MrasRatGTP-dependent protein binding enablesISOMRAS (Homo sapiens)1624291UniProtKB:Q92565 and PMID:10934204RGDPMID:10934204
MrasRatGTPase activity enablesIEAInterPro:IPR0018061600115GO_REF:0000002InterProGO_REF:0000002
MrasRatGTPase activity enablesIBACGD:CAL0000181665 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
MrasRatGTPase activity enablesISOMRAS (Homo sapiens)1624291 PMID:28289718RGDPMID:28289718
MrasRathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
MrasRatnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
MrasRatprotein binding enablesIPIUniProtKB:O087738554645PMID:19319189UniProt 
MrasRatprotein binding enablesISOMRAS (Homo sapiens)1624291UniProtKB:Q9UQ13 more ...RGDPMID:25137548 more ...
1 to 13 of 13 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MrasRatmitogen activated protein kinase signaling pathway   IEA 6907045 KEGGrno:04010

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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Novel small GTPase M-Ras participates in reorganization of actin cytoskeleton. Matsumoto K, etal., Oncogene 1997 Nov 13;15(20):2409-17.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
10. Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector. Willard FS, etal., PLoS One. 2009;4(3):e4884. doi: 10.1371/journal.pone.0004884. Epub 2009 Mar 25.
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PMID:10934204   PMID:12477932   PMID:16923128   PMID:19444311   PMID:20439489   PMID:23376485   PMID:28289718  



Mras
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,823,374 - 108,886,104 (-)NCBIGRCr8
mRatBN7.2899,944,036 - 100,006,771 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,944,036 - 99,996,408 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8105,610,343 - 105,663,748 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08103,809,642 - 103,863,053 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08101,652,159 - 101,705,561 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08107,629,028 - 107,656,851 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8107,629,028 - 107,681,512 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08107,054,728 - 107,082,497 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48104,244,660 - 104,272,556 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18104,264,114 - 104,292,011 (-)NCBI
Celera899,345,811 - 99,373,539 (-)NCBICelera
Cytogenetic Map8q31NCBI
MRAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383138,347,648 - 138,405,535 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3138,347,648 - 138,405,534 (+)EnsemblGRCh38hg38GRCh38
GRCh373138,066,490 - 138,124,377 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363139,549,315 - 139,607,067 (+)NCBINCBI36Build 36hg18NCBI36
Build 343139,574,404 - 139,607,073NCBI
Celera3136,491,513 - 136,549,286 (+)NCBICelera
Cytogenetic Map3q22.3NCBI
HuRef3135,441,552 - 135,499,356 (+)NCBIHuRef
CHM1_13138,030,261 - 138,088,159 (+)NCBICHM1_1
T2T-CHM13v2.03141,088,198 - 141,146,101 (+)NCBIT2T-CHM13v2.0
Mras
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39999,267,473 - 99,319,505 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl999,267,473 - 99,319,434 (-)EnsemblGRCm39 Ensembl
GRCm38999,385,420 - 99,437,700 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl999,385,420 - 99,437,381 (-)EnsemblGRCm38mm10GRCm38
MGSCv37999,285,839 - 99,337,131 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36999,197,328 - 99,246,063 (-)NCBIMGSCv36mm8
Celera998,920,430 - 98,971,712 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.63NCBI
Mras
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955501615,303 - 670,782 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955501615,303 - 670,404 (-)NCBIChiLan1.0ChiLan1.0
MRAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22136,253,974 - 136,311,964 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13136,258,713 - 136,316,693 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03135,377,488 - 135,435,338 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13142,827,020 - 142,884,582 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3142,827,020 - 142,884,582 (+)Ensemblpanpan1.1panPan2
MRAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12334,558,278 - 34,613,987 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2334,582,314 - 34,611,763 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2334,550,398 - 34,607,319 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02335,098,326 - 35,155,275 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2335,099,325 - 35,157,728 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12334,779,709 - 34,836,613 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02334,845,153 - 34,902,406 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02335,096,331 - 35,153,294 (+)NCBIUU_Cfam_GSD_1.0
Mras
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560273,933,041 - 73,985,346 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936540672,544 - 725,143 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936540672,783 - 725,129 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1379,139,764 - 79,211,135 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11379,137,489 - 79,211,139 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21386,781,175 - 86,826,924 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11552,137,409 - 52,195,247 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1552,135,727 - 52,170,020 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604125,149,689 - 25,208,288 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mras
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473014,879,484 - 14,940,255 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473014,879,631 - 14,938,683 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Mras
269 total Variants

Predicted Target Of
Summary Value
Count of predictions:962
Count of miRNA genes:331
Interacting mature miRNAs:443
Transcripts:ENSRNOT00000050374
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 28 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)888612425107550209Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat

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alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000050374   ⟹   ENSRNOP00000045851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl899,944,036 - 99,978,327 (-)Ensembl
Rnor_6.0 Ensembl8107,629,028 - 107,656,861 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000077963   ⟹   ENSRNOP00000072543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl899,946,502 - 99,996,408 (-)Ensembl
Rnor_6.0 Ensembl8107,631,488 - 107,681,512 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118697   ⟹   ENSRNOP00000085134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl899,944,036 - 99,973,929 (-)Ensembl
RefSeq Acc Id: NM_001388501   ⟹   NP_001375430
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88108,823,374 - 108,876,147 (-)NCBI
mRatBN7.2899,944,036 - 99,996,814 (-)NCBI
RefSeq Acc Id: NM_012981   ⟹   NP_037113
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88108,823,374 - 108,875,911 (-)NCBI
mRatBN7.2899,944,036 - 99,996,578 (-)NCBI
Rnor_6.08107,629,028 - 107,656,851 (-)NCBI
Rnor_5.08107,054,728 - 107,082,497 (-)NCBI
RGSC_v3.48104,244,660 - 104,272,556 (-)RGD
Celera899,345,811 - 99,373,539 (-)RGD
Sequence:
RefSeq Acc Id: XM_039080883   ⟹   XP_038936811
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88108,823,377 - 108,857,628 (-)NCBI
mRatBN7.2899,944,039 - 99,978,326 (-)NCBI
RefSeq Acc Id: XM_039080884   ⟹   XP_038936812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88108,823,377 - 108,875,859 (-)NCBI
mRatBN7.2899,944,039 - 99,996,526 (-)NCBI
RefSeq Acc Id: XM_039080887   ⟹   XP_038936815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88108,823,377 - 108,886,104 (-)NCBI
mRatBN7.2899,944,039 - 100,006,771 (-)NCBI
RefSeq Acc Id: XM_063264949   ⟹   XP_063121019
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88108,823,377 - 108,875,859 (-)NCBI
RefSeq Acc Id: NP_037113   ⟸   NM_012981
- UniProtKB: P97538 (UniProtKB/Swiss-Prot),   O09021 (UniProtKB/Swiss-Prot),   Q5RKJ7 (UniProtKB/TrEMBL),   A6I2D6 (UniProtKB/TrEMBL),   A0A0G2K389 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072543   ⟸   ENSRNOT00000077963
Ensembl Acc Id: ENSRNOP00000045851   ⟸   ENSRNOT00000050374
RefSeq Acc Id: NP_001375430   ⟸   NM_001388501
- UniProtKB: P97538 (UniProtKB/Swiss-Prot),   O09021 (UniProtKB/Swiss-Prot),   Q5RKJ7 (UniProtKB/TrEMBL),   A6I2D6 (UniProtKB/TrEMBL),   A0A0G2K389 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936815   ⟸   XM_039080887
- Peptide Label: isoform X2
- UniProtKB: P97538 (UniProtKB/Swiss-Prot),   O09021 (UniProtKB/Swiss-Prot),   Q5RKJ7 (UniProtKB/TrEMBL),   A6I2D6 (UniProtKB/TrEMBL),   A0A0G2K389 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-P97538-F1-model_v2 AlphaFold P97538 1-208 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29396 BioCyc
Ensembl Genes ENSRNOG00000014060 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000050374 ENTREZGENE
  ENSRNOT00000118697 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7130510 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  Small_GTPase UniProtKB/Swiss-Prot
  Small_GTPase_Ras-type UniProtKB/Swiss-Prot
MGC_CLONE MGC:93575 IMAGE-MGC_LOAD
NCBI Gene 25482 ENTREZGENE
PANTHER PTHR24070 UniProtKB/Swiss-Prot
Pfam Ras UniProtKB/Swiss-Prot
PhenoGen Mras PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot
PROSITE RAS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014060 RatGTEx
SMART RAB UniProtKB/Swiss-Prot
  RAN UniProtKB/Swiss-Prot
  RAS UniProtKB/Swiss-Prot
  RHO UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
TIGR TC206441
UniProt A0A0G2K389 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A109 ENTREZGENE, UniProtKB/TrEMBL
  A6I2D6 ENTREZGENE, UniProtKB/TrEMBL
  F7FMZ0 ENTREZGENE, UniProtKB/TrEMBL
  O09021 ENTREZGENE
  P97538 ENTREZGENE
  Q5RKJ7 ENTREZGENE
  RASM_RAT UniProtKB/Swiss-Prot
UniProt Secondary O09021 UniProtKB/Swiss-Prot
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-11 Mras  muscle RAS oncogene homolog  Mras  muscle and microspikes RAS  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Mras  Muscle and microspikes RAS      Symbol and Name status set to approved 70586 APPROVED

Note Type Note Reference
gene_function has GTP-binding and GTPase activities 729080