Symbol:
Anpep
Name:
alanyl aminopeptidase, membrane
RGD ID:
2991
Description:
Enables aminopeptidase activity and peptide binding activity. Involved in metanephric proximal tubule development; peptide catabolic process; and protein processing. Located in brush border membrane. Orthologous to human ANPEP (alanyl aminopeptidase, membrane); PARTICIPATES IN angiotensin IV signaling pathway; renin-angiotensin cascade pathway; glutathione metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,2,2-tetramine.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
alanyl (membrane) aminopeptidase; alanyl aminopeptidase; aminopeptidase M; aminopeptidase N; AP-M; AP-N; Apm; APN; cluster of differentiation antigen 13 (CD13); kidney aminopeptidase M; kidney Zn peptidase; KZP; Lap1; leucine arylaminopeptidase 1; membrane alanine aminopeptidase; microsomal aminopeptidase; rAPN
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ANPEP (alanyl aminopeptidase, membrane) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Anpep (alanyl aminopeptidase, membrane) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Anpep (alanyl aminopeptidase, membrane) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ANPEP (alanyl aminopeptidase, membrane) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ANPEP (alanyl aminopeptidase, membrane) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Anpep (alanyl aminopeptidase, membrane) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ANPEP (alanyl aminopeptidase, membrane) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
ANPEP (alanyl aminopeptidase, membrane) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Anpep (alanyl aminopeptidase, membrane) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Anpep (alanyl aminopeptidase, membrane)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
ANPEP (alanyl aminopeptidase, membrane)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
si:ch211-106j24.1
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Danio rerio (zebrafish):
anpepb (alanyl (membrane) aminopeptidase b)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
si:ch211-276a23.5
Alliance
DIOPT (OrthoFinder|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
CG14516
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoInspector|PANTHER|SonicParanoid)
Drosophila melanogaster (fruit fly):
CG31445
Alliance
DIOPT (Ensembl Compara|Hieranoid|OMA|OrthoInspector|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
SP1029
Alliance
DIOPT (Ensembl Compara|Hieranoid|OMA|OrthoInspector|PANTHER)
Drosophila melanogaster (fruit fly):
CG11951
Alliance
DIOPT (Ensembl Compara|Hieranoid|OMA|OrthoInspector|PANTHER)
Caenorhabditis elegans (roundworm):
anp-1
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA|OrthoInspector|PANTHER|SonicParanoid)
Drosophila melanogaster (fruit fly):
CG46339
Alliance
DIOPT (Ensembl Compara|OMA|PANTHER|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):
TMA108
Alliance
DIOPT (Ensembl Compara|PANTHER)
Xenopus tropicalis (tropical clawed frog):
anpep
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Candidate Gene For:
Mcs32
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 143,176,645 - 143,219,447 (-) NCBI GRCr8 mRatBN7.2 1 133,767,332 - 133,810,137 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 133,767,332 - 133,785,789 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 141,676,519 - 141,695,002 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 148,845,924 - 148,864,407 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 141,763,630 - 141,782,111 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 141,561,364 - 141,604,249 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 141,561,334 - 141,604,273 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 142,522,426 - 142,565,721 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 135,600,751 - 135,619,208 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 135,679,156 - 135,697,614 (-) NCBI Celera 1 125,830,648 - 125,849,086 (-) NCBI Celera RH 3.4 Map 1 1063.2 RGD Cytogenetic Map 1 q31 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Anpep Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ANPEP mRNA] CTD PMID:31150632 Anpep Rat (1->4)-beta-D-glucan multiple interactions ISO Anpep (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ANPEP mRNA CTD PMID:36331819 Anpep Rat 1,10-phenanthroline decreases activity ISO ANPEP (Homo sapiens) 6480464 1 and 10-phenanthroline results in decreased activity of ANPEP protein CTD PMID:17109655 Anpep Rat 1,10-phenanthroline multiple interactions ISO ANPEP (Homo sapiens) 6480464 Edetic Acid promotes the reaction [1 and 10-phenanthroline results in decreased activity of ANPEP protein] CTD PMID:17109655 Anpep Rat 1,2-dimethylhydrazine multiple interactions ISO Anpep (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANPEP mRNA CTD PMID:22206623 Anpep Rat 1,2-dimethylhydrazine decreases expression ISO Anpep (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of ANPEP mRNA CTD PMID:22206623 Anpep Rat 17beta-estradiol affects expression ISO ANPEP (Homo sapiens) 6480464 Estradiol affects the expression of ANPEP mRNA CTD PMID:22574217 Anpep Rat 17beta-estradiol decreases expression ISO Anpep (Mus musculus) 6480464 Estradiol results in decreased expression of ANPEP mRNA CTD PMID:39298647 Anpep Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of ANPEP mRNA CTD PMID:32145629 Anpep Rat 17beta-estradiol multiple interactions ISO ANPEP (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of ANPEP mRNA CTD PMID:30165855 Anpep Rat 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of ANPEP mRNA CTD PMID:26496021 Anpep Rat 17beta-estradiol increases expression ISO Anpep (Mus musculus) 6480464 Estradiol results in increased expression of ANPEP mRNA CTD PMID:19484750 Anpep Rat 2,2,2-tetramine multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in decreased expression of ANPEP protein] CTD PMID:19634143 Anpep Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Anpep (Mus musculus) 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of ANPEP mRNA CTD PMID:16214954 Anpep Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ANPEP mRNA CTD PMID:34747641 Anpep Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Anpep (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ANPEP mRNA CTD PMID:18796159 and PMID:26290441 Anpep Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO ANPEP (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of ANPEP mRNA CTD PMID:11489354 more ... Anpep Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ANPEP mRNA CTD PMID:21215274 Anpep Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Anpep (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of ANPEP mRNA CTD PMID:19933214 Anpep Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO ANPEP (Homo sapiens) 6480464 2 more ... CTD PMID:26705709 Anpep Rat 2-bromohexadecanoic acid multiple interactions ISO ANPEP (Homo sapiens) 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of ANPEP protein] CTD PMID:38195004 Anpep Rat 2-palmitoylglycerol increases expression ISO ANPEP (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of ANPEP mRNA CTD PMID:37199045 Anpep Rat 3,3',4,4',5-pentachlorobiphenyl increases expression ISO ANPEP (Homo sapiens) 6480464 3 more ... CTD PMID:35618242 Anpep Rat 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO Anpep (Mus musculus) 6480464 3 more ... CTD PMID:19467301 Anpep Rat 4,4'-sulfonyldiphenol increases expression ISO Anpep (Mus musculus) 6480464 bisphenol S results in increased expression of ANPEP mRNA CTD PMID:30951980 Anpep Rat 4,4'-sulfonyldiphenol affects methylation ISO Anpep (Mus musculus) 6480464 bisphenol S affects the methylation of ANPEP gene CTD PMID:31683443 Anpep Rat 4,4'-sulfonyldiphenol decreases methylation ISO Anpep (Mus musculus) 6480464 bisphenol S results in decreased methylation of ANPEP exon CTD PMID:33297965 Anpep Rat 4,4'-sulfonyldiphenol decreases expression ISO Anpep (Mus musculus) 6480464 bisphenol S results in decreased expression of ANPEP mRNA CTD PMID:39298647 Anpep Rat 4-hydroxyphenyl retinamide decreases activity ISO ANPEP (Homo sapiens) 6480464 Fenretinide results in decreased activity of ANPEP protein CTD PMID:15958647 Anpep Rat 5-aza-2'-deoxycytidine increases expression ISO ANPEP (Homo sapiens) 6480464 Decitabine results in increased expression of ANPEP mRNA CTD PMID:19194470 Anpep Rat 5-aza-2'-deoxycytidine multiple interactions ISO ANPEP (Homo sapiens) 6480464 Decitabine promotes the reaction [Phenylbutyrates results in increased expression of ANPEP protein] CTD PMID:15946563 Anpep Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ANPEP mRNA CTD PMID:25825206 Anpep Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of ANPEP mRNA CTD PMID:31881176 Anpep Rat acetylsalicylic acid increases activity ISO ANPEP (Homo sapiens) 6480464 Aspirin results in increased activity of ANPEP protein CTD PMID:16216591 Anpep Rat acetylsalicylic acid increases expression ISO ANPEP (Homo sapiens) 6480464 Aspirin results in increased expression of ANPEP mRNA and Aspirin results in increased expression of ANPEP protein CTD PMID:16216591 Anpep Rat aflatoxin B1 decreases expression ISO ANPEP (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of ANPEP mRNA CTD PMID:27153756 Anpep Rat all-trans-retinoic acid decreases expression ISO ANPEP (Homo sapiens) 6480464 Tretinoin results in decreased expression of ANPEP mRNA CTD PMID:33167477 Anpep Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ANPEP mRNA CTD PMID:16483693 Anpep Rat antirheumatic drug decreases expression ISO ANPEP (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of ANPEP mRNA CTD PMID:24449571 Anpep Rat Aroclor 1254 increases expression ISO Anpep (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of ANPEP mRNA CTD PMID:23650126 Anpep Rat arsane increases expression EXP 6480464 Arsenic results in increased expression of ANPEP mRNA CTD PMID:18315880 Anpep Rat arsane multiple interactions ISO ANPEP (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ANPEP mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ANPEP mRNA CTD PMID:39836092 Anpep Rat arsane affects methylation ISO ANPEP (Homo sapiens) 6480464 Arsenic affects the methylation of ANPEP gene CTD PMID:25304211 Anpep Rat arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of ANPEP mRNA CTD PMID:18315880 Anpep Rat arsenic atom multiple interactions ISO ANPEP (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ANPEP mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ANPEP mRNA CTD PMID:39836092 Anpep Rat arsenic atom affects methylation ISO ANPEP (Homo sapiens) 6480464 Arsenic affects the methylation of ANPEP gene CTD PMID:25304211 Anpep Rat arsenite(3-) multiple interactions ISO ANPEP (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to ANPEP protein] CTD PMID:32406909 Anpep Rat arsenous acid decreases expression ISO ANPEP (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of ANPEP mRNA CTD PMID:15949261 Anpep Rat benzene multiple interactions EXP 6480464 [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of ANPEP mRNA CTD PMID:17905399 Anpep Rat benzene increases expression ISO ANPEP (Homo sapiens) 6480464 Benzene results in increased expression of ANPEP mRNA CTD PMID:19162166 Anpep Rat benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of ANPEP mRNA CTD PMID:21839799 Anpep Rat benzo[a]pyrene increases methylation ISO ANPEP (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ANPEP 3' UTR and Benzo(a)pyrene results in increased methylation of ANPEP 5' UTR CTD PMID:27901495 Anpep Rat benzo[a]pyrene affects methylation ISO ANPEP (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ANPEP promoter CTD PMID:27901495 Anpep Rat benzo[a]pyrene multiple interactions ISO Anpep (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ANPEP mRNA CTD PMID:27858113 Anpep Rat benzo[b]fluoranthene multiple interactions ISO Anpep (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ANPEP mRNA CTD PMID:27858113 Anpep Rat bis(2-ethylhexyl) phthalate multiple interactions ISO Anpep (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ANPEP mRNA CTD PMID:39150890 Anpep Rat bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 Genistein promotes the reaction [Diethylhexyl Phthalate affects the expression of ANPEP mRNA] CTD PMID:32533902 Anpep Rat bis(2-ethylhexyl) phthalate affects expression EXP 6480464 Diethylhexyl Phthalate affects the expression of ANPEP mRNA CTD PMID:32533902 Anpep Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of ANPEP mRNA CTD PMID:26496021 Anpep Rat bisphenol A decreases expression ISO ANPEP (Homo sapiens) 6480464 bisphenol A results in decreased expression of ANPEP protein CTD PMID:34186270 Anpep Rat bisphenol A decreases expression ISO Anpep (Mus musculus) 6480464 bisphenol A results in decreased expression of ANPEP mRNA CTD PMID:33221593 Anpep Rat bisphenol A affects expression ISO ANPEP (Homo sapiens) 6480464 bisphenol A affects the expression of ANPEP mRNA CTD PMID:30903817 Anpep Rat bisphenol A increases expression ISO Anpep (Mus musculus) 6480464 bisphenol A results in increased expression of ANPEP mRNA CTD PMID:30951980 and PMID:32156529 Anpep Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ANPEP mRNA CTD PMID:25181051 more ... Anpep Rat bisphenol AF increases expression ISO ANPEP (Homo sapiens) 6480464 bisphenol AF results in increased expression of ANPEP protein CTD PMID:34186270 Anpep Rat Bisphenol B increases expression ISO ANPEP (Homo sapiens) 6480464 bisphenol B results in increased expression of ANPEP protein CTD PMID:34186270 Anpep Rat bisphenol F increases expression ISO Anpep (Mus musculus) 6480464 bisphenol F results in increased expression of ANPEP mRNA CTD PMID:30951980 Anpep Rat buta-1,3-diene decreases expression ISO Anpep (Mus musculus) 6480464 1 and 3-butadiene results in decreased expression of ANPEP mRNA CTD PMID:29038090 Anpep Rat Butylbenzyl phthalate multiple interactions ISO Anpep (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ANPEP mRNA CTD PMID:39150890 Anpep Rat C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of ANPEP mRNA CTD PMID:19167457 Anpep Rat cadmium atom multiple interactions ISO ANPEP (Homo sapiens) 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of ANPEP protein] more ... CTD PMID:29741670 and PMID:38195004 Anpep Rat cadmium dichloride multiple interactions ISO ANPEP (Homo sapiens) 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of ANPEP protein] more ... CTD PMID:29741670 and PMID:38195004 Anpep Rat cadmium dichloride increases expression ISO ANPEP (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of ANPEP mRNA CTD PMID:38382870 Anpep Rat cannabidiol increases expression ISO ANPEP (Homo sapiens) 6480464 Cannabidiol results in increased expression of ANPEP mRNA CTD PMID:27932991 Anpep Rat carbon nanotube decreases expression ISO Anpep (Mus musculus) 6480464 Nanotubes and Carbon results in decreased expression of ANPEP mRNA CTD PMID:25554681 Anpep Rat chromium(6+) affects expression ISO Anpep (Mus musculus) 6480464 chromium hexavalent ion affects the expression of ANPEP mRNA CTD PMID:28472532 Anpep Rat chrysene multiple interactions ISO Anpep (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ANPEP mRNA CTD PMID:27858113 Anpep Rat cisplatin decreases expression ISO ANPEP (Homo sapiens) 6480464 Cisplatin results in decreased expression of ANPEP mRNA CTD PMID:27594783 Anpep Rat cobalt dichloride affects expression ISO ANPEP (Homo sapiens) 6480464 cobaltous chloride affects the expression of ANPEP mRNA CTD PMID:20105288 Anpep Rat cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of ANPEP mRNA CTD PMID:24386269 Anpep Rat cobalt dichloride decreases expression ISO ANPEP (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of ANPEP mRNA CTD PMID:19320972 Anpep Rat copper atom decreases expression EXP 6480464 Copper results in decreased expression of ANPEP mRNA CTD PMID:22465980 Anpep Rat copper(0) decreases expression EXP 6480464 Copper results in decreased expression of ANPEP mRNA CTD PMID:22465980 Anpep Rat copper(II) chloride decreases expression ISO ANPEP (Homo sapiens) 6480464 cupric chloride results in decreased expression of ANPEP mRNA CTD PMID:17211630 Anpep Rat copper(II) sulfate decreases expression ISO ANPEP (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of ANPEP mRNA CTD PMID:19549813 Anpep Rat crocidolite asbestos decreases expression ISO Anpep (Mus musculus) 6480464 Asbestos and Crocidolite results in decreased expression of ANPEP mRNA CTD PMID:29279043 Anpep Rat crocidolite asbestos increases expression ISO Anpep (Mus musculus) 6480464 Asbestos and Crocidolite results in increased expression of ANPEP mRNA CTD PMID:19446018 Anpep Rat crocidolite asbestos increases expression ISO ANPEP (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of ANPEP mRNA CTD PMID:24160326 Anpep Rat cyclosporin A increases secretion EXP 6480464 Cyclosporine results in increased secretion of ANPEP protein CTD PMID:7514309 Anpep Rat cyclosporin A decreases expression ISO ANPEP (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ANPEP mRNA CTD PMID:20106945 more ... Anpep Rat daidzein multiple interactions ISO ANPEP (Homo sapiens) 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 Anpep Rat daidzein 7-O-beta-D-glucoside multiple interactions ISO ANPEP (Homo sapiens) 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 Anpep Rat DDT decreases expression EXP 6480464 DDT results in decreased expression of ANPEP mRNA CTD PMID:30207508 Anpep Rat deoxynivalenol decreases expression ISO ANPEP (Homo sapiens) 6480464 deoxynivalenol results in decreased expression of ANPEP mRNA CTD PMID:31863870 Anpep Rat diarsenic trioxide decreases expression ISO ANPEP (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of ANPEP mRNA CTD PMID:15949261 Anpep Rat Dibutyl phosphate affects expression ISO ANPEP (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of ANPEP mRNA CTD PMID:37042841 Anpep Rat dibutyl phthalate multiple interactions ISO Anpep (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ANPEP mRNA CTD PMID:39150890 Anpep Rat dicrotophos increases expression ISO ANPEP (Homo sapiens) 6480464 dicrotophos results in increased expression of ANPEP mRNA CTD PMID:28302478 Anpep Rat diethyl phthalate multiple interactions ISO Anpep (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ANPEP mRNA CTD PMID:39150890 Anpep Rat diethylstilbestrol increases expression ISO ANPEP (Homo sapiens) 6480464 Diethylstilbestrol results in increased expression of ANPEP mRNA CTD PMID:19371625 Anpep Rat diisobutyl phthalate multiple interactions ISO Anpep (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ANPEP mRNA CTD PMID:39150890 Anpep Rat diisononyl phthalate multiple interactions ISO Anpep (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of ANPEP mRNA CTD PMID:39150890 Anpep Rat diuron decreases expression EXP 6480464 Diuron results in decreased expression of ANPEP mRNA CTD PMID:21551480 and PMID:25152437 Anpep Rat elemental selenium increases expression ISO ANPEP (Homo sapiens) 6480464 Selenium results in increased expression of ANPEP mRNA CTD PMID:19244175 Anpep Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of ANPEP mRNA CTD PMID:29391264 Anpep Rat ethylenediaminetetraacetic acid multiple interactions ISO ANPEP (Homo sapiens) 6480464 Edetic Acid promotes the reaction [1 and 10-phenanthroline results in decreased activity of ANPEP protein] CTD PMID:17109655 Anpep Rat fenthion increases expression ISO Anpep (Mus musculus) 6480464 Fenthion results in increased expression of ANPEP mRNA CTD PMID:34813904 Anpep Rat flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of ANPEP mRNA CTD PMID:24136188 Anpep Rat folic acid multiple interactions ISO Anpep (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANPEP mRNA CTD PMID:22206623 Anpep Rat furan increases methylation EXP 6480464 furan results in increased methylation of ANPEP gene CTD PMID:22079235 Anpep Rat furan increases expression EXP 6480464 furan results in increased expression of ANPEP mRNA CTD PMID:26194646 Anpep Rat genistein multiple interactions ISO ANPEP (Homo sapiens) 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 Anpep Rat genistein multiple interactions EXP 6480464 Genistein promotes the reaction [Diethylhexyl Phthalate affects the expression of ANPEP mRNA] CTD PMID:32533902 Anpep Rat genistein 7-O-beta-D-glucoside multiple interactions ISO ANPEP (Homo sapiens) 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 Anpep Rat gentamycin increases secretion ISO ANPEP (Homo sapiens) 6480464 Gentamicins results in increased secretion of ANPEP protein CTD PMID:582724 Anpep Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of ANPEP mRNA CTD PMID:33387578 Anpep Rat glycitein multiple interactions ISO ANPEP (Homo sapiens) 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 Anpep Rat glycitin multiple interactions ISO ANPEP (Homo sapiens) 6480464 [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 Anpep Rat GW 4064 increases expression ISO Anpep (Mus musculus) 6480464 GW 4064 results in increased expression of ANPEP mRNA CTD PMID:26655953 Anpep Rat inulin multiple interactions ISO Anpep (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ANPEP mRNA CTD PMID:36331819 Anpep Rat ivermectin decreases expression ISO ANPEP (Homo sapiens) 6480464 Ivermectin results in decreased expression of ANPEP protein CTD PMID:32959892 Anpep Rat L-ascorbic acid multiple interactions ISO ANPEP (Homo sapiens) 6480464 [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ANPEP mRNA CTD PMID:17639512 Anpep Rat manganese atom multiple interactions ISO ANPEP (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ANPEP mRNA CTD PMID:39836092 Anpep Rat manganese(0) multiple interactions ISO ANPEP (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ANPEP mRNA CTD PMID:39836092 Anpep Rat manganese(II) chloride multiple interactions ISO ANPEP (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ANPEP mRNA CTD PMID:39836092 Anpep Rat methidathion increases expression ISO Anpep (Mus musculus) 6480464 methidathion results in increased expression of ANPEP mRNA CTD PMID:34813904 Anpep Rat methotrexate increases expression ISO ANPEP (Homo sapiens) 6480464 Methotrexate results in increased expression of ANPEP protein CTD PMID:2877729 Anpep Rat methylmercury chloride increases expression ISO ANPEP (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of ANPEP mRNA CTD PMID:28001369 Anpep Rat methylmercury(1+) multiple interactions EXP 6480464 [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of ANPEP mRNA CTD PMID:17905399 Anpep Rat mifepristone decreases expression ISO ANPEP (Homo sapiens) 6480464 Mifepristone results in decreased expression of ANPEP mRNA CTD PMID:17584828 Anpep Rat nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of ANPEP mRNA CTD PMID:24136188 Anpep Rat nickel atom decreases expression ISO ANPEP (Homo sapiens) 6480464 Nickel results in decreased expression of ANPEP mRNA CTD PMID:23195993 Anpep Rat nickel atom increases expression ISO ANPEP (Homo sapiens) 6480464 Nickel results in increased expression of ANPEP mRNA CTD PMID:24768652 and PMID:25583101 Anpep Rat nickel sulfate decreases expression ISO Anpep (Mus musculus) 6480464 nickel sulfate results in decreased expression of ANPEP mRNA CTD PMID:16166746 Anpep Rat nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of ANPEP mRNA CTD PMID:24136188 Anpep Rat ozone multiple interactions ISO Anpep (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ANPEP mRNA CTD PMID:34911549 Anpep Rat ozone increases expression ISO Anpep (Mus musculus) 6480464 Ozone results in increased expression of ANPEP mRNA CTD PMID:33026818 Anpep Rat paracetamol affects expression ISO Anpep (Mus musculus) 6480464 Acetaminophen affects the expression of ANPEP mRNA CTD PMID:17562736 Anpep Rat paracetamol decreases expression ISO ANPEP (Homo sapiens) 6480464 Acetaminophen results in decreased expression of ANPEP mRNA CTD PMID:29067470 Anpep Rat PD 0325901 decreases expression ISO ANPEP (Homo sapiens) 6480464 mirdametinib results in decreased expression of ANPEP mRNA CTD PMID:25119042 Anpep Rat perfluorohexanesulfonic acid multiple interactions ISO Anpep (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2 more ... CTD PMID:36270329 Anpep Rat perfluorononanoic acid multiple interactions ISO Anpep (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2 more ... CTD PMID:36270329 Anpep Rat perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of ANPEP mRNA CTD PMID:19162173 Anpep Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Anpep (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ANPEP mRNA more ... CTD PMID:36270329 and PMID:36331819 Anpep Rat perfluorooctanoic acid multiple interactions ISO Anpep (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2 more ... CTD PMID:36270329 Anpep Rat phenobarbital multiple interactions ISO Anpep (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ANPEP mRNA] CTD PMID:19482888 Anpep Rat phenobarbital affects expression ISO Anpep (Mus musculus) 6480464 Phenobarbital affects the expression of ANPEP mRNA CTD PMID:23091169 Anpep Rat phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of ANPEP mRNA CTD PMID:19162173 Anpep Rat phenobarbital increases expression ISO Anpep (Mus musculus) 6480464 Phenobarbital results in increased expression of ANPEP mRNA CTD PMID:19482888 Anpep Rat pirimiphos-methyl decreases activity EXP 6480464 pirimiphos methyl results in decreased activity of ANPEP protein CTD PMID:9204212 Anpep Rat pirinixic acid multiple interactions ISO Anpep (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ANPEP mRNA CTD PMID:19710929 Anpep Rat pirinixic acid increases expression ISO Anpep (Mus musculus) 6480464 pirinixic acid results in increased expression of ANPEP mRNA CTD PMID:18301758 and PMID:23811191 Anpep Rat porphyrins decreases activity ISO ANPEP (Homo sapiens) 6480464 Porphyrins analog results in decreased activity of ANPEP protein CTD PMID:19189318 Anpep Rat potassium chromate decreases expression ISO ANPEP (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of ANPEP mRNA CTD PMID:22714537 Anpep Rat pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of ANPEP mRNA CTD PMID:19162173 Anpep Rat quercetin multiple interactions ISO ANPEP (Homo sapiens) 6480464 [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ANPEP mRNA CTD PMID:17639512 Anpep Rat rotenone increases expression ISO ANPEP (Homo sapiens) 6480464 Rotenone results in increased expression of ANPEP protein CTD PMID:8833408 Anpep Rat selenium atom increases expression ISO ANPEP (Homo sapiens) 6480464 Selenium results in increased expression of ANPEP mRNA CTD PMID:19244175 Anpep Rat serpentine asbestos increases expression ISO ANPEP (Homo sapiens) 6480464 Asbestos and Serpentine results in increased expression of ANPEP mRNA CTD PMID:24160326 Anpep Rat silicon dioxide increases expression ISO ANPEP (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of ANPEP mRNA CTD PMID:25895662 Anpep Rat silicon dioxide increases expression ISO Anpep (Mus musculus) 6480464 Silicon Dioxide results in increased expression of ANPEP mRNA CTD PMID:29203145 Anpep Rat simvastatin increases expression ISO Anpep (Mus musculus) 6480464 Simvastatin results in increased expression of ANPEP mRNA CTD PMID:19262002 Anpep Rat sodium arsenate decreases expression ISO Anpep (Mus musculus) 6480464 sodium arsenate results in decreased expression of ANPEP mRNA CTD PMID:21795629 Anpep Rat sodium arsenite decreases expression ISO Anpep (Mus musculus) 6480464 sodium arsenite results in decreased expression of ANPEP protein CTD PMID:29044176 Anpep Rat sodium arsenite multiple interactions ISO ANPEP (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ANPEP mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ANPEP mRNA CTD PMID:39836092 Anpep Rat sodium arsenite decreases expression ISO ANPEP (Homo sapiens) 6480464 sodium arsenite results in decreased expression of ANPEP mRNA CTD PMID:38568856 Anpep Rat Soman decreases expression EXP 6480464 Soman results in decreased expression of ANPEP mRNA CTD PMID:19281266 Anpep Rat Soman increases expression EXP 6480464 Soman results in increased expression of ANPEP mRNA CTD PMID:19281266 Anpep Rat sotorasib multiple interactions ISO ANPEP (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANPEP mRNA CTD PMID:36139627 Anpep Rat streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of ANPEP protein CTD PMID:19634143 Anpep Rat streptozocin multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in decreased expression of ANPEP protein] CTD PMID:19634143 Anpep Rat succimer multiple interactions ISO Anpep (Mus musculus) 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ANPEP mRNA CTD PMID:26378955 Anpep Rat tacrolimus hydrate increases secretion EXP 6480464 Tacrolimus results in increased secretion of ANPEP protein CTD PMID:7514309 Anpep Rat tamoxifen affects expression ISO Anpep (Mus musculus) 6480464 Tamoxifen affects the expression of ANPEP mRNA CTD PMID:20937368 Anpep Rat tert-butyl hydroperoxide increases expression ISO ANPEP (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of ANPEP mRNA CTD PMID:15336504 Anpep Rat Tesaglitazar increases expression EXP 6480464 tesaglitazar results in increased expression of ANPEP mRNA CTD PMID:21515302 Anpep Rat tetrachloromethane decreases expression ISO Anpep (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of ANPEP mRNA CTD PMID:17484886 Anpep Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ANPEP mRNA CTD PMID:31150632 Anpep Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ANPEP mRNA] CTD PMID:31150632 Anpep Rat tetraphene multiple interactions ISO Anpep (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ANPEP mRNA CTD PMID:27858113 Anpep Rat thimerosal decreases expression ISO ANPEP (Homo sapiens) 6480464 Thimerosal results in decreased expression of ANPEP mRNA CTD PMID:27188386 Anpep Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of ANPEP mRNA CTD PMID:34492290 Anpep Rat thiram decreases expression ISO ANPEP (Homo sapiens) 6480464 Thiram results in decreased expression of ANPEP mRNA CTD PMID:38568856 Anpep Rat tobramycin decreases activity EXP 6480464 Tobramycin results in decreased activity of ANPEP protein CTD PMID:6653171 Anpep Rat toluene increases expression EXP 6480464 Toluene results in increased expression of ANPEP mRNA CTD PMID:22967744 Anpep Rat trametinib multiple interactions ISO ANPEP (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ANPEP mRNA CTD PMID:36139627 Anpep Rat trichloroethene multiple interactions EXP 6480464 [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of ANPEP mRNA CTD PMID:17905399 Anpep Rat triphenyl phosphate affects expression ISO ANPEP (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ANPEP mRNA CTD PMID:37042841 Anpep Rat Triptolide affects expression EXP 6480464 triptolide affects the expression of ANPEP protein CTD PMID:32519852 Anpep Rat triptonide decreases expression ISO Anpep (Mus musculus) 6480464 triptonide results in decreased expression of ANPEP mRNA CTD PMID:33045310 Anpep Rat troglitazone increases expression ISO ANPEP (Homo sapiens) 6480464 troglitazone results in increased expression of ANPEP mRNA CTD PMID:19140230 Anpep Rat valproic acid affects expression ISO ANPEP (Homo sapiens) 6480464 Valproic Acid affects the expression of ANPEP mRNA CTD PMID:25979313 Anpep Rat valproic acid decreases expression ISO ANPEP (Homo sapiens) 6480464 Valproic Acid results in decreased expression of ANPEP mRNA CTD PMID:28001369 and PMID:29154799 Anpep Rat valproic acid decreases methylation ISO ANPEP (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of ANPEP gene CTD PMID:28853863 and PMID:29201983 Anpep Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of ANPEP mRNA CTD PMID:19015723 Anpep Rat vorinostat decreases expression ISO ANPEP (Homo sapiens) 6480464 vorinostat results in decreased expression of ANPEP mRNA CTD PMID:27188386 Anpep Rat zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of ANPEP mRNA CTD PMID:11717422 Anpep Rat zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of ANPEP mRNA CTD PMID:11717422 Anpep Rat zoledronic acid increases expression ISO ANPEP (Homo sapiens) 6480464 zoledronic acid results in increased expression of ANPEP mRNA CTD PMID:24714768
Imported Annotations - SMPDB
Imported Annotations - KEGG (archival)
(+)-schisandrin B (EXP) (1->4)-beta-D-glucan (ISO) 1,10-phenanthroline (ISO) 1,2-dimethylhydrazine (ISO) 17beta-estradiol (EXP,ISO) 2,2,2-tetramine (EXP) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 2-bromohexadecanoic acid (ISO) 2-palmitoylglycerol (ISO) 3,3',4,4',5-pentachlorobiphenyl (ISO) 3,3',4,4'-tetrachlorobiphenyl (ISO) 4,4'-sulfonyldiphenol (ISO) 4-hydroxyphenyl retinamide (ISO) 5-aza-2'-deoxycytidine (ISO) 6-propyl-2-thiouracil (EXP) acetamide (EXP) acetylsalicylic acid (ISO) aflatoxin B1 (ISO) all-trans-retinoic acid (ISO) ammonium chloride (EXP) antirheumatic drug (ISO) Aroclor 1254 (ISO) arsane (EXP,ISO) arsenic atom (EXP,ISO) arsenite(3-) (ISO) arsenous acid (ISO) benzene (EXP,ISO) benzo[a]pyrene (EXP,ISO) benzo[b]fluoranthene (ISO) bis(2-ethylhexyl) phthalate (EXP,ISO) bisphenol A (EXP,ISO) bisphenol AF (ISO) Bisphenol B (ISO) bisphenol F (ISO) buta-1,3-diene (ISO) Butylbenzyl phthalate (ISO) C60 fullerene (EXP) cadmium atom (ISO) cadmium dichloride (ISO) cannabidiol (ISO) carbon nanotube (ISO) chromium(6+) (ISO) chrysene (ISO) cisplatin (ISO) cobalt dichloride (EXP,ISO) copper atom (EXP) copper(0) (EXP) copper(II) chloride (ISO) copper(II) sulfate (ISO) crocidolite asbestos (ISO) cyclosporin A (EXP,ISO) daidzein (ISO) daidzein 7-O-beta-D-glucoside (ISO) DDT (EXP) deoxynivalenol (ISO) diarsenic trioxide (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (ISO) dicrotophos (ISO) diethyl phthalate (ISO) diethylstilbestrol (ISO) diisobutyl phthalate (ISO) diisononyl phthalate (ISO) diuron (EXP) elemental selenium (ISO) endosulfan (EXP) ethylenediaminetetraacetic acid (ISO) fenthion (ISO) flutamide (EXP) folic acid (ISO) furan (EXP) genistein (EXP,ISO) genistein 7-O-beta-D-glucoside (ISO) gentamycin (EXP,ISO) glycitein (ISO) glycitin (ISO) GW 4064 (ISO) inulin (ISO) ivermectin (ISO) L-ascorbic acid (ISO) manganese atom (ISO) manganese(0) (ISO) manganese(II) chloride (ISO) methidathion (ISO) methotrexate (ISO) methylmercury chloride (ISO) methylmercury(1+) (EXP) mifepristone (ISO) nefazodone (EXP) nickel atom (ISO) nickel sulfate (ISO) nimesulide (EXP) ozone (ISO) paracetamol (ISO) PD 0325901 (ISO) perfluorohexanesulfonic acid (ISO) perfluorononanoic acid (ISO) perfluorooctane-1-sulfonic acid (EXP,ISO) perfluorooctanoic acid (ISO) phenobarbital (EXP,ISO) pirimiphos-methyl (EXP) pirinixic acid (ISO) porphyrins (ISO) potassium chromate (ISO) pregnenolone 16alpha-carbonitrile (EXP) quercetin (ISO) rotenone (ISO) selenium atom (ISO) serpentine asbestos (ISO) silicon dioxide (ISO) simvastatin (ISO) sodium arsenate (ISO) sodium arsenite (ISO) Soman (EXP) sotorasib (ISO) streptozocin (EXP) succimer (ISO) tacrolimus hydrate (EXP) tamoxifen (ISO) tert-butyl hydroperoxide (ISO) Tesaglitazar (EXP) tetrachloromethane (EXP,ISO) tetraphene (ISO) thimerosal (ISO) thioacetamide (EXP) thiram (ISO) tobramycin (EXP) toluene (EXP) trametinib (ISO) trichloroethene (EXP) triphenyl phosphate (ISO) Triptolide (EXP) triptonide (ISO) troglitazone (ISO) valproic acid (ISO) vinclozolin (EXP) vorinostat (ISO) zinc atom (EXP) zinc(0) (EXP) zoledronic acid (ISO)
1.
Renin-angiotensin system-regulating aminopeptidase activities are modified in the pineal gland of rats with breast cancer induced by N-methyl-nitrosourea.
Carrera MP, etal., Cancer Invest. 2006 Mar;24(2):149-53.
2.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
4.
KEGG: Kyoto Encyclopedia of Genes and Genomes
KEGG
5.
Elucidating the molecular physiopathology of acute respiratory distress syndrome in severe acute respiratory syndrome patients.
Kong SL, etal., Virus Res. 2009 Nov;145(2):260-9. Epub 2009 Jul 25.
6.
High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.
Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
7.
Targeting the renin-angiotensin system: what's new?
Leckie BJ Curr Med Chem Cardiovasc Hematol Agents. 2005 Jan;3(1):23-32.
8.
Molecular cloning and amino acid sequence of rat kidney aminopeptidase M: a member of a super family of zinc-metallohydrolases.
Malfroy B, etal., Biochem Biophys Res Commun 1989 May 30;161(1):236-41.
9.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
10.
Renogenic characterization and in vitro differentiation of rat amniotic fluid stem cells into renal proximal tubular- and juxtaglomerular-like cells.
Minocha E, etal., In Vitro Cell Dev Biol Anim. 2019 Feb;55(2):138-147. doi: 10.1007/s11626-018-00315-2. Epub 2019 Jan 15.
11.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
12.
Intrarenal aminopeptidase N inhibition restores defective angiontesin II type 2-mediated natriuresis in spontaneously hypertensive rats.
Padia SH, etal., Hypertension. 2010 Feb;55(2):474-80. Epub 2009 Dec 7.
13.
Insulin-regulated aminopeptidase/placental leucil Aminopeptidase (IRAP/P-lAP) and angiotensin IV-forming activities are modified in serum of rats with breast cancer induced by N-methyl-nitrosourea.
Pilar Carrera M, etal., Anticancer Res. 2006 Mar-Apr;26(2A):1011-4.
14.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
15.
SMPDB Annotation Import Pipeline
Pipeline to import SMPDB annotations from SMPDB into RGD
16.
The luminal membrane of rat thick limb expresses AT1 receptor and aminopeptidase activities.
Poumarat JS, etal., Kidney Int. 2002 Aug;62(2):434-45.
17.
GOA pipeline
RGD automated data pipeline
18.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
20.
Rat brain contains high levels of mannose-6-phosphorylated glycoproteins including lysosomal enzymes and palmitoyl-protein thioesterase, an enzyme implicated in infantile neuronal lipofuscinosis.
Sleat DE, etal., J Biol Chem. 1996 Aug 9;271(32):19191-8.
21.
Amino acid sequence deduced from a rat kidney cDNA suggests it encodes the Zn-peptidase aminopeptidase N.
Watt VM and Yip CC, J Biol Chem 1989 Apr 5;264(10):5480-7.
22.
Human aminopeptidase N is a receptor for human coronavirus 229E.
Yeager CL, etal., Nature 1992 Jun 4;357(6377):420-2.
Anpep Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 143,176,645 - 143,219,447 (-) NCBI GRCr8 mRatBN7.2 1 133,767,332 - 133,810,137 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 133,767,332 - 133,785,789 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 141,676,519 - 141,695,002 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 148,845,924 - 148,864,407 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 141,763,630 - 141,782,111 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 141,561,364 - 141,604,249 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 141,561,334 - 141,604,273 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 142,522,426 - 142,565,721 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 135,600,751 - 135,619,208 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 135,679,156 - 135,697,614 (-) NCBI Celera 1 125,830,648 - 125,849,086 (-) NCBI Celera RH 3.4 Map 1 1063.2 RGD Cytogenetic Map 1 q31 NCBI
ANPEP Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 15 89,784,895 - 89,814,852 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 15 89,784,895 - 89,815,401 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 15 90,328,126 - 90,358,084 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 15 88,129,130 - 88,159,076 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 15 88,129,130 - 88,150,938 NCBI Celera 15 66,730,914 - 66,760,859 (-) NCBI Celera Cytogenetic Map 15 q26.1 NCBI HuRef 15 66,440,812 - 66,470,613 (-) NCBI HuRef CHM1_1 15 90,169,132 - 90,199,097 (-) NCBI CHM1_1 T2T-CHM13v2.0 15 87,540,783 - 87,570,713 (-) NCBI T2T-CHM13v2.0
Anpep Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 7 79,471,551 - 79,497,958 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 7 79,471,551 - 79,510,807 (-) Ensembl GRCm39 Ensembl GRCm38 7 79,821,803 - 79,848,210 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 7 79,821,803 - 79,861,059 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 7 86,966,689 - 86,987,238 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 7 79,695,316 - 79,715,797 (-) NCBI MGSCv36 mm8 Celera 7 77,221,100 - 77,243,027 (-) NCBI Celera Cytogenetic Map 7 D2 NCBI cM Map 7 45.19 NCBI
Anpep Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955416 15,424,932 - 15,444,075 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955416 15,415,981 - 15,442,032 (+) NCBI ChiLan1.0 ChiLan1.0
ANPEP Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 16 79,335,577 - 79,365,554 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 15 83,037,936 - 83,059,833 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 15 68,479,349 - 68,509,238 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 15 87,681,826 - 87,703,713 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 15 87,681,826 - 87,703,713 (-) Ensembl panpan1.1 panPan2
ANPEP Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 3 52,764,418 - 52,779,516 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 3 52,764,418 - 52,779,746 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 3 55,398,319 - 55,413,377 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 3 53,181,131 - 53,196,208 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 3 53,181,130 - 53,203,507 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 3 52,702,917 - 52,717,931 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 3 52,912,916 - 52,927,956 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 3 53,253,252 - 53,268,352 (-) NCBI UU_Cfam_GSD_1.0
Anpep Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024408640 130,745,212 - 130,770,994 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936483 15,563,528 - 15,589,601 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936483 15,563,540 - 15,582,521 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
ANPEP Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 7 55,351,087 - 55,373,881 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 7 55,351,081 - 55,373,856 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 7 60,240,144 - 60,262,909 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3 Pig Cytomap 7 cen-q21 NCBI
ANPEP Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 29 8,324,094 - 8,354,491 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 29 8,323,797 - 8,346,581 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666059 38,429,007 - 38,487,801 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Anpep
.
Predicted Target Of
Count of predictions: 62 Count of miRNA genes: 54 Interacting mature miRNAs: 61 Transcripts: ENSRNOT00000020002 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
61442 Strs1 Sensitivity to stroke QTL 1 7.4 cerebrum integrity trait (VT:0010549) post-insult time to onset of cerebrovascular lesion (CMO:0002343) 1 121767634 166767634 Rat 1578780 Cm52 Cardiac mass QTL 52 3.3 0.0001 heart mass (VT:0007028) heart wet weight (CMO:0000069) 1 81591954 219808434 Rat 1578654 Bss10 Bone structure and strength QTL 10 4 femur morphology trait (VT:0000559) femoral neck cortical cross-sectional area (CMO:0001702) 1 49393172 159356837 Rat 1598866 Bp287 Blood pressure QTL 287 5.1 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 121006655 166006655 Rat 1578770 Stresp23 Stress response QTL 23 kidney sympathetic nerve activity (VT:0004050) stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786) 1 123350408 182418476 Rat 9590300 Scort16 Serum corticosterone level QTL 16 4.39 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 1 103111621 148111621 Rat 2298545 Neuinf8 Neuroinflammation QTL 8 4.6 nervous system integrity trait (VT:0010566) spinal cord beta-2 microglobulin mRNA level (CMO:0002125) 1 57336763 151090257 Rat 7794788 Mcs32 Mammary carcinoma susceptibility QTL 32 2.61 mammary gland integrity trait (VT:0010552) mammary tumor incidence/prevalence measurement (CMO:0000946) 1 115540693 238914717 Rat 631199 Cm23 Cardiac mass QTL 23 4.6 0.0004 heart left ventricle mass (VT:0007031) heart left ventricle wet weight (CMO:0000071) 1 115585465 172949803 Rat 2313402 Anxrr24 Anxiety related response QTL 24 aggression-related behavior trait (VT:0015014) tameness/aggressiveness composite score (CMO:0002136) 1 48963584 144267916 Rat 1598850 Bp297 Blood pressure QTL 297 2.1 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 121006655 166006655 Rat 631570 Bp94 Blood pressure QTL 94 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 123479780 142990467 Rat 152025235 Bw194 Body weight QTL 194 4.86 body mass (VT:0001259) 1 123556856 242907031 Rat 152025232 Bw192 Body weight QTL 192 3.93 body mass (VT:0001259) 1 117917486 196963478 Rat 724521 Uae1 Urinary albumin excretion QTL 1 3.8 0.0001 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 1 90508614 173018436 Rat 1358902 Bw47 Body weight QTL 47 1.67 body mass (VT:0001259) body weight (CMO:0000012) 1 90508614 180359386 Rat 61346 Rf2 Renal disease susceptibility QTL 2 3.7 urine protein amount (VT:0005160) urine protein level (CMO:0000591) 1 99267916 144267916 Rat 8655649 Arrd1 Age-related retinal degeneration QTL 1 4.89 retinal layer morphology trait (VT:0003727) percentage of study population developing retinopathy during a period of time (CMO:0002453) 1 100357752 183970443 Rat 1300153 Bp171 Blood pressure QTL 171 3.37 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 1 90664883 143200202 Rat 2317833 Alcrsp19 Alcohol response QTL 19 12.4 0.001 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 1 100979852 145979852 Rat 731168 Bp154 Blood pressure QTL 154 3.4 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 94642644 214537671 Rat 631202 Gluco13 Glucose level QTL 13 0.0001 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 1 131763437 159756369 Rat 631205 Bp196 Blood pressure QTL 196 4 0.0001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 118944897 199050459 Rat 1300158 Bp173 Blood pressure QTL 173 3.48 arterial blood pressure trait (VT:2000000) blood pressure time series experimental set point of the baroreceptor response (CMO:0002593) 1 115540693 185145286 Rat 1641897 Alcrsp1 Alcohol response QTL 1 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 1 100979852 145979852 Rat 1331749 Hrtrt11 Heart rate QTL 11 2.973 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 1 94494440 198211706 Rat 1331751 Bp199 Blood pressure QTL 199 3.60022 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 1 94494440 181830018 Rat 2293142 Bp314 Blood pressure QTL 314 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 92184926 137184926 Rat 9685799 Bp375 Blood pressure QTL 375 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 125611501 170611501 Rat 2293140 Bp313 Blood pressure QTL 313 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 121833674 166833674 Rat 9685802 Bp376 Blood pressure QTL 376 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 126540680 171540680 Rat 724529 Cm16 Cardiac mass QTL 16 2.7 heart mass (VT:0007028) calculated heart weight (CMO:0000073) 1 87580395 150700247 Rat 61370 Mcs3 Mammary carcinoma susceptibility QTL 3 2.15 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 1 102268556 147268556 Rat 1641895 Bp298 Blood pressure QTL 298 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 123350408 182418476 Rat 70209 Niddm23 Non-insulin dependent diabetes mellitus QTL 23 2.82 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 94494440 198324465 Rat 631496 Bp97 Blood pressure QTL 97 3.08 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 106047847 151047847 Rat 634314 Niddm44 Non-insulin dependent diabetes mellitus QTL 44 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 49393289 199050459 Rat 2303591 Gluco41 Glucose level QTL 41 2 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 102168504 147168504 Rat 1331793 Bp200 Blood pressure QTL 200 3.71601 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 94494440 172949803 Rat 2313060 Bss71 Bone structure and strength QTL 71 2.6 0.0001 long bone metaphysis morphology trait (VT:0000133) tibia midshaft total cross-sectional area (CMO:0001715) 1 118944747 163944747 Rat 6893347 Bw98 Body weight QTL 98 0.2 0.53 body mass (VT:0001259) body weight (CMO:0000012) 1 133680936 178680936 Rat 1354591 Cm36 Cardiac mass QTL 36 4.1 heart left ventricle mass (VT:0007031) calculated heart weight (CMO:0000073) 1 102813953 201278233 Rat 7421630 Bp362 Blood pressure QTL 362 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 118608292 241799120 Rat 70225 Bp58 Blood pressure QTL 58 3.3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 32356093 162846471 Rat 10059597 Bp377 Blood pressure QTL 377 3.42 0.025 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 32737458 199368955 Rat 61399 Tcat1 Tongue tumor resistance QTL 1 3.3 tongue integrity trait (VT:0010553) number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879) 1 99267916 144267916 Rat 6893361 Bw104 Body weight QTL 104 0.59 0.27 body mass (VT:0001259) body weight (CMO:0000012) 1 133680936 178680936 Rat 724567 Tcas6 Tongue tumor susceptibility QTL 6 6.85 tongue integrity trait (VT:0010553) number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950) 1 92948896 144267916 Rat 738006 Anxrr14 Anxiety related response QTL 14 4 0.00035 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 1 130636910 175636910 Rat 1558645 Bw55 Body weight QTL 55 3.2 0.004 body mass (VT:0001259) body weight (CMO:0000012) 1 133680936 178680936 Rat 1354615 Cm32 Cardiac mass QTL 32 5.2 heart left ventricle mass (VT:0007031) heart left ventricle wet weight (CMO:0000071) 1 102813953 201278233 Rat 634348 Bp138 Blood pressure QTL 138 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 125611501 168883176 Rat 8694370 Bw154 Body weight QTL 154 8.91 0.001 body lean mass (VT:0010483) lean tissue morphological measurement (CMO:0002184) 1 103111621 148111621 Rat 738028 Anxrr12 Anxiety related response QTL 12 4.9 0.00001 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 1 130636910 175636910 Rat 1354623 Rf46 Renal function QTL 46 3.8 blood creatinine amount (VT:0005328) plasma creatinine level (CMO:0000537) 1 102813953 151162766 Rat 631654 Bp107 Blood pressure QTL 107 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 125611501 170611501 Rat 631544 Bp84 Blood pressure QTL 84 5.6 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 123350408 181759564 Rat 152025212 Bw190 Body weight QTL 190 5.7 body mass (VT:0001259) 1 123556856 196963478 Rat 631549 Bp89 Blood pressure QTL 89 5.7 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 123350581 201284552 Rat 1358189 Cstrr1 Cold stress response QTL 1 0.0001 catecholamine amount (VT:0010543) urine norepinephrine level (CMO:0001629) 1 123350408 182418476 Rat 1354606 Bp246 Blood pressure QTL 246 3.6 arterial blood pressure trait (VT:2000000) pulse pressure (CMO:0000292) 1 102813953 218753816 Rat
D1Rat350
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 1 143,196,215 - 143,196,370 (+) Marker Load Pipeline mRatBN7.2 1 133,786,907 - 133,787,062 (+) MAPPER mRatBN7.2 Rnor_6.0 1 141,580,935 - 141,581,089 NCBI Rnor6.0 Rnor_5.0 1 142,541,997 - 142,542,151 UniSTS Rnor5.0 RGSC_v3.4 1 135,620,322 - 135,620,477 RGD RGSC3.4 RGSC_v3.4 1 135,620,323 - 135,620,477 UniSTS RGSC3.4 RGSC_v3.1 1 135,698,729 - 135,698,883 RGD Celera 1 125,850,075 - 125,850,229 UniSTS RH 3.4 Map 1 1058.1 UniSTS RH 3.4 Map 1 1058.1 RGD SHRSP x BN Map 1 68.8399 UniSTS SHRSP x BN Map 1 68.8399 RGD FHH x ACI Map 1 67.73 RGD Cytogenetic Map 1 q31 UniSTS
RH130139
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 1 133,767,436 - 133,767,626 (+) MAPPER mRatBN7.2 Rnor_6.0 1 141,561,469 - 141,561,658 NCBI Rnor6.0 Rnor_5.0 1 142,522,531 - 142,522,720 UniSTS Rnor5.0 RGSC_v3.4 1 135,600,856 - 135,601,045 UniSTS RGSC3.4 Celera 1 125,830,753 - 125,830,942 UniSTS RH 3.4 Map 1 1062.9 UniSTS Cytogenetic Map 1 q31 UniSTS
RH94699
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 1 133,767,385 - 133,767,584 (+) MAPPER mRatBN7.2 Rnor_6.0 1 141,561,418 - 141,561,616 NCBI Rnor6.0 Rnor_5.0 1 142,522,480 - 142,522,678 UniSTS Rnor5.0 RGSC_v3.4 1 135,600,805 - 135,601,003 UniSTS RGSC3.4 Celera 1 125,830,702 - 125,830,900 UniSTS RH 3.4 Map 1 1063.2 UniSTS Cytogenetic Map 1 q31 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
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Ensembl Acc Id:
ENSRNOT00000020002 ⟹ ENSRNOP00000020002
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 1 133,767,332 - 133,785,789 (-) Ensembl Rnor_6.0 Ensembl 1 141,561,457 - 141,579,871 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000092125 ⟹ ENSRNOP00000069456
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 1 133,767,332 - 133,785,789 (-) Ensembl Rnor_6.0 Ensembl 1 141,561,334 - 141,604,273 (-) Ensembl
RefSeq Acc Id:
NM_031012 ⟹ NP_112274
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 143,176,645 - 143,195,101 (-) NCBI mRatBN7.2 1 133,767,332 - 133,785,789 (-) NCBI Rnor_6.0 1 141,561,364 - 141,579,820 (-) NCBI Rnor_5.0 1 142,522,426 - 142,565,721 (-) NCBI RGSC_v3.4 1 135,600,751 - 135,619,208 (-) RGD Celera 1 125,830,648 - 125,849,086 (-) RGD
Sequence:
CTCCCTGCCCACCAGCATCATGGCCAAGGGTTTCTACATTTCCAAGACCCTGGGCATCTTGGGCATCCTGTTAGGTGTGGCAGCCGTATGCACCATCATAGCTCTGTCGGTGGTCTACGCTCAGGAGA
hide sequence
RefSeq Acc Id:
XM_006229407 ⟹ XP_006229469
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 143,176,646 - 143,200,776 (-) NCBI mRatBN7.2 1 133,767,333 - 133,791,462 (-) NCBI Rnor_6.0 1 141,561,365 - 141,585,498 (-) NCBI Rnor_5.0 1 142,522,426 - 142,565,721 (-) NCBI
Sequence:
ACTTCCCTTTAACCCGCGGGGCCGGGCGGGCGGGCGGCGGCAAGGCAGGAGCAGCTCGGAGCAGCGCGCTGTCCTAGGAAGATTAGTGTCACCGCCTTTCCCCCTGCCTCTGGGTGCCAAGCCTGCAG
hide sequence
RefSeq Acc Id:
XM_006229408 ⟹ XP_006229470
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 143,176,646 - 143,197,340 (-) NCBI mRatBN7.2 1 133,767,333 - 133,788,027 (-) NCBI Rnor_6.0 1 141,561,365 - 141,582,066 (-) NCBI Rnor_5.0 1 142,522,426 - 142,565,721 (-) NCBI
Sequence:
GAGACCAGAGGGCCGGGCAGAATCTAGCTCTTTGTTTGGAGAGGGGATTAACCGAATGGACTTG
hide sequence
RefSeq Acc Id:
XM_006229409 ⟹ XP_006229471
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 143,176,646 - 143,219,447 (-) NCBI mRatBN7.2 1 133,767,333 - 133,810,137 (-) NCBI Rnor_6.0 1 141,561,365 - 141,604,249 (-) NCBI Rnor_5.0 1 142,522,426 - 142,565,721 (-) NCBI
Sequence:
TCCCATTCTGGGCCAGTATGTGAGAGACAGAGGGGTATGGAACCTATTCTTTCCTGAGTTAGGACTCTGTGGGAAGGATACAGGAAGGAAGTCCTGCCAACCGCCATCCCGAGGGAGGGGCTTCAGAA
hide sequence
RefSeq Acc Id:
NP_112274 ⟸ NM_031012
- Peptide Label:
precursor
- UniProtKB:
Q9JHP4 (UniProtKB/Swiss-Prot), P15684 (UniProtKB/Swiss-Prot), A0A0G2JVE6 (UniProtKB/TrEMBL)
- Sequence:
MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSAIAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYIFKGSSTVRFTCNETTNVIIIHSKKLN
hide sequence
RefSeq Acc Id:
XP_006229471 ⟸ XM_006229409
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2JVE6 (UniProtKB/TrEMBL), A6JC72 (UniProtKB/TrEMBL), G3V7W7 (UniProtKB/TrEMBL)
- Sequence:
MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSAIAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYIFKGSSTVRFTCNETTNVIIIHSKKLN
hide sequence
RefSeq Acc Id:
XP_006229469 ⟸ XM_006229407
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2JVE6 (UniProtKB/TrEMBL), A6JC72 (UniProtKB/TrEMBL), G3V7W7 (UniProtKB/TrEMBL)
- Sequence:
MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSAIAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYIFKGSSTVRFTCNETTNVIIIHSKKLN
hide sequence
RefSeq Acc Id:
XP_006229470 ⟸ XM_006229408
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2JVE6 (UniProtKB/TrEMBL), A6JC72 (UniProtKB/TrEMBL), G3V7W7 (UniProtKB/TrEMBL)
- Sequence:
MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSAIAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYIFKGSSTVRFTCNETTNVIIIHSKKLN
hide sequence
Ensembl Acc Id:
ENSRNOP00000069456 ⟸ ENSRNOT00000092125
Ensembl Acc Id:
ENSRNOP00000020002 ⟸ ENSRNOT00000020002
RGD ID: 13690135 Promoter ID: EPDNEW_R657 Type: multiple initiation site Name: Anpep_1 Description: alanyl aminopeptidase, membrane SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 1 141,579,844 - 141,579,904 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2016-01-13
Anpep
alanyl aminopeptidase, membrane
Anpep
alanyl (membrane) aminopeptidase
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2002-06-10
Anpep
alanyl (membrane) aminopeptidase
Symbol and Name status set to approved
70586 APPROVED
2001-12-10
Anpep
alanyl (membrane) aminopeptidase
Symbol and Name updated to reflect Human and Mouse nomenclature
69665 APPROVED
Note Type
Note
Reference
gene_expression
expressed in large amount in kidney, lung, liver, heart and aorta
69943
gene_expression
expressed in large amount in kidney, lung, liver, heart and aorta
69944
gene_function
broad specificity aminopeptidase; found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells
724707
gene_process
plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases; may be involved in the metabolism of regulatory peptides of diverse cell types; may have a role in angiogenesis
724707
gene_process
plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases
69943
gene_process
plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases
69944
gene_product
glycoprotein, member of the peptidase family m1 (zinc metalloprotease)
69943
gene_product
glycoprotein, member of the peptidase family m1 (zinc metalloprotease)
69944
gene_protein
965 amino acids, 140 kDa
69943
gene_protein
965 amino acids, 140 kDa
69944
