Symbol:
Gss
Name:
glutathione synthetase
RGD ID:
2752
Description:
Enables several functions, including anion binding activity; glutathione synthase activity; and identical protein binding activity. Involved in several processes, including glutathione biosynthetic process; response to amino acid; and response to tumor necrosis factor. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in Alzheimer's disease; congenital nonspherocytic hemolytic anemia 6; glutathione synthetase deficiency; and glutatione synthetase deficiency with 5-oxoprolinuria. Orthologous to human GSS (glutathione synthetase); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; glutamic acid/glutamate metabolic pathway; glutathione metabolic pathway; INTERACTS WITH (R)-lipoic acid; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
glutathione synthase; Glutathione synthetase gene; GSH synthetase; GSH-S
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
GSS (glutathione synthetase) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Gss (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Gss (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
GSS (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
GSS (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Gss (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
GSS (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
GSS (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Gss (glutathione synthetase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Gss (glutathione synthetase)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
GSS (glutathione synthetase)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
gss (glutathione synthetase)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
GSH2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Drosophila melanogaster (fruit fly):
Gss1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Drosophila melanogaster (fruit fly):
Gss2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Caenorhabditis elegans (roundworm):
gss-1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
gss
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 164,508,005 - 164,538,343 (-) NCBI GRCr8 mRatBN7.2 3 144,047,849 - 144,078,197 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 144,047,850 - 144,078,198 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 3 147,914,375 - 147,944,469 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 156,531,652 - 156,561,750 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 154,271,186 - 154,301,288 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 3 151,076,254 - 151,106,557 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 151,076,254 - 151,106,557 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 157,443,738 - 157,474,042 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 146,057,517 - 146,087,820 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 3 145,963,138 - 145,993,442 (-) NCBI Celera 3 142,772,407 - 142,802,700 (-) NCBI Celera Cytogenetic Map 3 q42 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Gss Rat (-)-epigallocatechin 3-gallate decreases expression ISO GSS (Homo sapiens) 6480464 epigallocatechin gallate results in decreased expression of GSS mRNA CTD PMID:18851785 Gss Rat (-)-epigallocatechin 3-gallate increases expression ISO Gss (Mus musculus) 6480464 epigallocatechin gallate results in increased expression of GSS mRNA CTD PMID:25585349 Gss Rat (-)-quinic acid multiple interactions ISO GSS (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with Quinic Acid analog] results in increased expression of GSS mRNA CTD PMID:21751221 Gss Rat (1->4)-beta-D-glucan multiple interactions ISO Gss (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GSS mRNA CTD PMID:36331819 Gss Rat (R)-lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [methylmercuric chloride results in decreased activity of GSS protein] CTD PMID:32061141 Gss Rat 1,2-dimethylhydrazine increases expression EXP 6480464 1 and 2-Dimethylhydrazine results in increased expression of GSS mRNA CTD PMID:32387197 Gss Rat 1,2-dimethylhydrazine multiple interactions ISO Gss (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of GSS mRNA] CTD PMID:22206623 Gss Rat 1,2-dimethylhydrazine increases expression ISO Gss (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of GSS mRNA CTD PMID:22206623 Gss Rat 1,4-benzoquinone increases expression ISO GSS (Homo sapiens) 6480464 quinone results in increased expression of GSS protein CTD PMID:21059386 Gss Rat 1,4-benzoquinone multiple interactions ISO GSS (Homo sapiens) 6480464 NFE2L2 mRNA affects the reaction [quinone results in increased expression of GSS protein] CTD PMID:21059386 Gss Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of GSS mRNA CTD PMID:20551477 Gss Rat 17alpha-ethynylestradiol increases expression ISO Gss (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of GSS mRNA CTD PMID:17942748 Gss Rat 17alpha-ethynylestradiol multiple interactions ISO Gss (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GSS mRNA CTD PMID:17942748 Gss Rat 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of GSS mRNA CTD PMID:17108234 and PMID:29097150 Gss Rat 17beta-estradiol decreases expression ISO GSS (Homo sapiens) 6480464 Estradiol results in decreased expression of GSS mRNA CTD PMID:16705744 Gss Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of GSS mRNA CTD PMID:32145629 Gss Rat 17beta-estradiol multiple interactions ISO Gss (Mus musculus) 6480464 [Polyphenols co-treated with Estradiol] results in decreased expression of GSS mRNA CTD PMID:30077407 Gss Rat 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO GSS (Homo sapiens) 6480464 Metribolone results in increased expression of GSS protein CTD PMID:17152098 Gss Rat 1H-pyrazole increases expression ISO Gss (Mus musculus) 6480464 pyrazole results in increased expression of GSS mRNA CTD PMID:17945193 Gss Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Gss (Mus musculus) 6480464 2 more ... CTD PMID:32352317 Gss Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Gss (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GSS mRNA CTD PMID:17942748 Gss Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Gss (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of GSS mRNA CTD PMID:21570461 Gss Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of GSS mRNA CTD PMID:21215274 and PMID:33387578 Gss Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Gss (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of GSS mRNA CTD PMID:15328365 and PMID:18163543 Gss Rat 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of GSS mRNA CTD PMID:21346803 Gss Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of GSS mRNA CTD PMID:21346803 Gss Rat 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of GSS mRNA CTD PMID:21346803 Gss Rat 2-acetamidofluorene increases expression ISO Gss (Mus musculus) 6480464 2-Acetylaminofluorene results in increased expression of GSS mRNA CTD PMID:17317680 Gss Rat 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of GSS mRNA CTD PMID:15890375 Gss Rat 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of GSS mRNA CTD PMID:10978506 Gss Rat 2-tert-butylhydroquinone multiple interactions ISO Gss (Mus musculus) 6480464 [2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of GSS mRNA CTD PMID:32428544 Gss Rat 2-tert-butylhydroquinone increases expression ISO Gss (Mus musculus) 6480464 2-tert-butylhydroquinone results in increased expression of GSS mRNA CTD PMID:19183254 and PMID:32428544 Gss Rat 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 Gss Rat 3,7-dihydropurine-6-thione increases expression ISO GSS (Homo sapiens) 6480464 Mercaptopurine results in increased expression of GSS mRNA CTD PMID:18222062 Gss Rat 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin analog results in increased expression of GSS protein and alpha-Chlorohydrin results in increased expression of GSS protein CTD PMID:26072098 and PMID:26597043 Gss Rat 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of GSS protein CTD PMID:26072098 Gss Rat 3-methylcholanthrene increases activity ISO Gss (Mus musculus) 6480464 Methylcholanthrene results in increased activity of GSS protein CTD PMID:23712962 Gss Rat 3-methylcholanthrene increases expression ISO Gss (Mus musculus) 6480464 Methylcholanthrene results in increased expression of GSS mRNA CTD PMID:23712962 Gss Rat 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1 and 2-dithiol-3-thione results in increased expression of GSS mRNA CTD PMID:19162173 Gss Rat 4,4'-diaminodiphenylmethane increases expression ISO Gss (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of GSS mRNA CTD PMID:18648102 Gss Rat 4,4'-sulfonyldiphenol increases expression ISO Gss (Mus musculus) 6480464 bisphenol S results in increased expression of GSS mRNA CTD PMID:39298647 Gss Rat 4,4'-sulfonyldiphenol increases expression ISO GSS (Homo sapiens) 6480464 bisphenol S results in increased expression of GSS protein CTD PMID:34186270 Gss Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSS mRNA CTD PMID:15890375 Gss Rat 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of GSS mRNA CTD PMID:21346803 Gss Rat 4-hydroxynon-2-enal increases expression ISO Gss (Mus musculus) 6480464 4-hydroxy-2-nonenal results in increased expression of GSS mRNA CTD PMID:19191707 Gss Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of GSS mRNA CTD PMID:39441382 Gss Rat 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:12376462 Gss Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of GSS mRNA CTD PMID:22459607 Gss Rat actinomycin D multiple interactions ISO GSS (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of and results in increased secretion of GSS protein CTD PMID:38460933 Gss Rat aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of GSS mRNA CTD PMID:15890375 Gss Rat aflatoxin B1 multiple interactions ISO Gss (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of GSS mRNA] CTD PMID:35063475 Gss Rat aflatoxin B1 decreases expression ISO Gss (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of GSS mRNA CTD PMID:35063475 Gss Rat aflatoxin B1 increases expression ISO Gss (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of GSS mRNA CTD PMID:19770486 Gss Rat all-trans-retinoic acid decreases expression ISO GSS (Homo sapiens) 6480464 Tretinoin results in decreased expression of GSS mRNA CTD PMID:33167477 Gss Rat alpha-D-galactose decreases expression ISO GSS (Homo sapiens) 6480464 Galactose results in decreased expression of GSS mRNA CTD PMID:23274001 Gss Rat alpha-D-galactose multiple interactions ISO GSS (Homo sapiens) 6480464 sodium bisulfide inhibits the reaction [Galactose results in decreased expression of GSS mRNA] CTD PMID:23274001 Gss Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of GSS mRNA CTD PMID:16483693 Gss Rat Anetholtrithion increases activity ISO GSS (Homo sapiens) 6480464 Anethole Trithione results in increased activity of GSS protein CTD PMID:11213483 Gss Rat arecoline decreases expression ISO GSS (Homo sapiens) 6480464 Arecoline results in decreased expression of GSS mRNA CTD PMID:17682004 Gss Rat aristolochic acid A increases expression ISO GSS (Homo sapiens) 6480464 aristolochic acid I results in increased expression of GSS mRNA and aristolochic acid I results in increased expression of GSS protein CTD PMID:33212167 Gss Rat arsane increases expression ISO GSS (Homo sapiens) 6480464 Arsenic results in increased expression of GSS protein CTD PMID:18487201 Gss Rat arsane increases expression ISO Gss (Mus musculus) 6480464 Arsenic results in increased expression of GSS mRNA and Arsenic results in increased expression of GSS protein CTD PMID:35523338 Gss Rat arsane multiple interactions ISO Gss (Mus musculus) 6480464 NFE2L2 protein affects the reaction [Arsenic results in increased expression of GSS mRNA] and NFE2L2 protein affects the reaction [Arsenic results in increased expression of GSS protein] CTD PMID:35523338 Gss Rat arsane multiple interactions ISO GSS (Homo sapiens) 6480464 [Arsenic results in increased expression of GSS protein] which results in increased chemical synthesis of Glutathione CTD PMID:18487201 Gss Rat arsenic atom increases expression ISO GSS (Homo sapiens) 6480464 Arsenic results in increased expression of GSS protein CTD PMID:18487201 Gss Rat arsenic atom increases expression ISO Gss (Mus musculus) 6480464 Arsenic results in increased expression of GSS mRNA and Arsenic results in increased expression of GSS protein CTD PMID:35523338 Gss Rat arsenic atom multiple interactions ISO Gss (Mus musculus) 6480464 NFE2L2 protein affects the reaction [Arsenic results in increased expression of GSS mRNA] and NFE2L2 protein affects the reaction [Arsenic results in increased expression of GSS protein] CTD PMID:35523338 Gss Rat arsenic atom multiple interactions ISO GSS (Homo sapiens) 6480464 [Arsenic results in increased expression of GSS protein] which results in increased chemical synthesis of Glutathione CTD PMID:18487201 Gss Rat azathioprine increases expression ISO GSS (Homo sapiens) 6480464 Azathioprine results in increased expression of GSS mRNA CTD PMID:18222062 Gss Rat Azoxymethane multiple interactions ISO Gss (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GSS mRNA CTD PMID:29950665 Gss Rat benzo[a]pyrene increases expression ISO Gss (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of GSS mRNA CTD PMID:19770486 and PMID:21715664 Gss Rat benzo[a]pyrene multiple interactions ISO Gss (Mus musculus) 6480464 [lipopolysaccharide and E coli O55-B5 co-treated with Benzo(a)pyrene] affects the expression of GSS mRNA CTD PMID:28987381 Gss Rat beta-lapachone decreases expression ISO GSS (Homo sapiens) 6480464 beta-lapachone results in decreased expression of GSS mRNA CTD PMID:38218311 Gss Rat bis(2-chloroethyl) sulfide increases expression ISO Gss (Mus musculus) 6480464 Mustard Gas results in increased expression of GSS mRNA CTD PMID:18955075 Gss Rat bis(2-ethylhexyl) phthalate increases expression ISO Gss (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of GSS mRNA CTD PMID:35917956 and PMID:36610486 Gss Rat bis(2-ethylhexyl) phthalate decreases expression ISO Gss (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of GSS mRNA CTD PMID:35550907 Gss Rat bis(2-ethylhexyl) phthalate multiple interactions ISO Gss (Mus musculus) 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSS mRNA] CTD PMID:35917956 and PMID:36610486 Gss Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GSS mRNA CTD PMID:25181051 more ... Gss Rat bisphenol A decreases expression ISO GSS (Homo sapiens) 6480464 bisphenol A results in decreased expression of GSS protein CTD PMID:34186270 Gss Rat bisphenol A multiple interactions ISO GSS (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of GSS gene CTD PMID:31601247 Gss Rat bisphenol A increases expression ISO GSS (Homo sapiens) 6480464 bisphenol A results in increased expression of GSS protein CTD PMID:33024228 and PMID:37567409 Gss Rat bisphenol A increases expression ISO Gss (Mus musculus) 6480464 bisphenol A results in increased expression of GSS mRNA CTD PMID:33221593 Gss Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of GSS gene CTD PMID:28505145 Gss Rat Bisphenol B increases expression ISO GSS (Homo sapiens) 6480464 bisphenol B results in increased expression of GSS protein CTD PMID:34186270 Gss Rat bisphenol F increases expression ISO Gss (Mus musculus) 6480464 bisphenol F results in increased expression of GSS mRNA CTD PMID:38685157 Gss Rat bisphenol F increases expression ISO GSS (Homo sapiens) 6480464 bisphenol F results in increased expression of GSS protein CTD PMID:34186270 Gss Rat butan-1-ol multiple interactions ISO GSS (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GSS mRNA CTD PMID:29432896 Gss Rat cadmium dichloride increases expression ISO GSS (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of GSS protein CTD PMID:24527689 Gss Rat cadmium dichloride increases expression ISO Gss (Mus musculus) 6480464 Cadmium Chloride results in increased expression of GSS mRNA CTD PMID:25528414 Gss Rat cadmium sulfide increases expression ISO GSS (Homo sapiens) 6480464 cadmium sulfide results in increased expression of GSS mRNA CTD PMID:27866839 Gss Rat celecoxib affects expression ISO Gss (Mus musculus) 6480464 Celecoxib affects the expression of GSS mRNA CTD PMID:20562220 Gss Rat chloroprene increases expression ISO Gss (Mus musculus) 6480464 Chloroprene results in increased expression of GSS mRNA CTD PMID:23125180 Gss Rat chlorpyrifos affects expression EXP 6480464 Chlorpyrifos affects the expression of GSS mRNA CTD PMID:19440498 Gss Rat cisplatin increases expression ISO GSS (Homo sapiens) 6480464 Cisplatin results in increased expression of GSS mRNA CTD PMID:27392435 and PMID:27594783 Gss Rat cisplatin multiple interactions ISO Gss (Mus musculus) 6480464 [2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of GSS mRNA CTD PMID:32428544 Gss Rat cisplatin increases expression ISO Gss (Mus musculus) 6480464 Cisplatin results in increased expression of GSS mRNA CTD PMID:32428544 Gss Rat cisplatin multiple interactions ISO GSS (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of GSS mRNA CTD PMID:27392435 Gss Rat clofibrate multiple interactions ISO Gss (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of GSS mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GSS mRNA] CTD PMID:17585979 Gss Rat cobalt dichloride decreases expression ISO GSS (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of GSS mRNA CTD PMID:19376846 Gss Rat copper atom decreases expression EXP 6480464 Copper results in decreased expression of GSS mRNA CTD PMID:22465980 Gss Rat copper atom affects binding ISO GSS (Homo sapiens) 6480464 GSS protein binds to Copper CTD PMID:15359738 Gss Rat copper(0) decreases expression EXP 6480464 Copper results in decreased expression of GSS mRNA CTD PMID:22465980 Gss Rat copper(0) affects binding ISO GSS (Homo sapiens) 6480464 GSS protein binds to Copper CTD PMID:15359738 Gss Rat copper(II) sulfate decreases expression ISO GSS (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of GSS mRNA CTD PMID:19549813 Gss Rat Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of GSS mRNA CTD PMID:26577399 Gss Rat curcumin increases expression ISO Gss (Mus musculus) 6480464 Curcumin results in increased expression of GSS mRNA CTD PMID:19183254 Gss Rat curcumin multiple interactions ISO Gss (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of GSS mRNA] CTD PMID:35063475 Gss Rat deoxynivalenol increases expression ISO GSS (Homo sapiens) 6480464 deoxynivalenol results in increased expression of GSS mRNA CTD PMID:37419272 Gss Rat deoxynivalenol multiple interactions ISO GSS (Homo sapiens) 6480464 Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GSS protein] and Resveratrol promotes the reaction [deoxynivalenol results in increased expression of GSS protein] CTD PMID:37419272 Gss Rat dextran sulfate multiple interactions ISO Gss (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GSS mRNA CTD PMID:29950665 Gss Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of GSS mRNA CTD PMID:21266533 Gss Rat dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of GSS mRNA CTD PMID:18636392 Gss Rat dichlorine increases expression EXP 6480464 Chlorine results in increased expression of GSS mRNA CTD PMID:18636392 Gss Rat diethyl malate multiple interactions ISO Gss (Mus musculus) 6480464 S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSS mRNA] CTD PMID:24814887 Gss Rat diethyl malate affects expression ISO Gss (Mus musculus) 6480464 diethyl malate affects the expression of GSS mRNA CTD PMID:24814887 Gss Rat diethyl maleate increases expression EXP 6480464 diethyl maleate results in increased expression of GSS mRNA CTD PMID:10978506 Gss Rat diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of GSS mRNA CTD PMID:15890375 Gss Rat diquat increases expression ISO GSS (Homo sapiens) 6480464 Diquat results in increased expression of GSS protein CTD PMID:38128689 Gss Rat enilconazole decreases expression ISO Gss (Mus musculus) 6480464 enilconazole results in decreased expression of GSS mRNA CTD PMID:29451352 Gss Rat erdosteine increases expression ISO Gss (Mus musculus) 6480464 erdosteine results in increased expression of GSS protein CTD PMID:26193055 Gss Rat ethanol multiple interactions ISO Gss (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of GSS mRNA CTD PMID:30517762 Gss Rat ethyl methanesulfonate increases expression ISO GSS (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of GSS mRNA CTD PMID:23649840 Gss Rat fenamidone increases expression ISO Gss (Mus musculus) 6480464 fenamidone results in increased expression of GSS mRNA CTD PMID:27029645 Gss Rat fenthion increases expression ISO Gss (Mus musculus) 6480464 Fenthion results in increased expression of GSS mRNA CTD PMID:34813904 Gss Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of GSS mRNA CTD PMID:24136188 Gss Rat flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of GSS mRNA CTD PMID:24793618 Gss Rat folic acid decreases expression ISO Gss (Mus musculus) 6480464 Folic Acid deficiency results in decreased expression of GSS CTD PMID:25384423 Gss Rat folic acid multiple interactions ISO Gss (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of GSS mRNA] CTD PMID:22206623 Gss Rat formaldehyde increases expression ISO GSS (Homo sapiens) 6480464 Formaldehyde results in increased expression of GSS mRNA CTD PMID:23649840 Gss Rat fulvestrant multiple interactions ISO GSS (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of GSS gene CTD PMID:31601247 Gss Rat furan increases expression EXP 6480464 furan results in increased expression of GSS mRNA CTD PMID:25539665 and PMID:27402187 Gss Rat galactose multiple interactions ISO GSS (Homo sapiens) 6480464 sodium bisulfide inhibits the reaction [Galactose results in decreased expression of GSS mRNA] CTD PMID:23274001 Gss Rat galactose decreases expression ISO GSS (Homo sapiens) 6480464 Galactose results in decreased expression of GSS mRNA CTD PMID:23274001 Gss Rat genistein decreases expression ISO GSS (Homo sapiens) 6480464 Genistein results in decreased expression of GSS mRNA CTD PMID:16705744 Gss Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of GSS mRNA CTD PMID:33387578 Gss Rat glafenine increases expression EXP 6480464 Glafenine results in increased expression of GSS mRNA CTD PMID:24136188 Gss Rat glutathione multiple interactions ISO GSS (Homo sapiens) 6480464 [Arsenic results in increased expression of GSS protein] which results in increased chemical synthesis of Glutathione CTD PMID:18487201 Gss Rat Glutathione ethyl ester multiple interactions ISO Gss (Mus musculus) 6480464 S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSS mRNA] CTD PMID:24814887 Gss Rat Hexachloro-1,3-butadiene decreases activity EXP 6480464 hexachlorobutadiene results in decreased activity of GSS protein CTD PMID:15669050 Gss Rat hydrogen peroxide increases expression ISO GSS (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of GSS mRNA CTD PMID:19902159 Gss Rat hydrogen peroxide multiple interactions ISO GSS (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with Quinic Acid analog] results in increased expression of GSS mRNA CTD PMID:21751221 Gss Rat hydroquinone increases expression ISO GSS (Homo sapiens) 6480464 hydroquinone results in increased expression of GSS protein CTD PMID:21059386 Gss Rat hydroquinone multiple interactions ISO GSS (Homo sapiens) 6480464 NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein] CTD PMID:21059386 Gss Rat hypochlorous acid increases expression ISO Gss (Mus musculus) 6480464 Hypochlorous Acid results in increased expression of GSS mRNA CTD PMID:17980396 Gss Rat indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of GSS mRNA CTD PMID:36868495 Gss Rat iron atom multiple interactions ISO GSS (Homo sapiens) 6480464 Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GSS mRNA] CTD PMID:19073151 Gss Rat iron atom decreases expression ISO GSS (Homo sapiens) 6480464 Iron results in decreased expression of GSS mRNA CTD PMID:19073151 Gss Rat iron(0) decreases expression ISO GSS (Homo sapiens) 6480464 Iron results in decreased expression of GSS mRNA CTD PMID:19073151 Gss Rat iron(0) multiple interactions ISO GSS (Homo sapiens) 6480464 Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GSS mRNA] CTD PMID:19073151 Gss Rat isoflurane decreases expression ISO Gss (Mus musculus) 6480464 Isoflurane results in decreased expression of GSS protein CTD PMID:35249202 Gss Rat ivermectin decreases expression ISO GSS (Homo sapiens) 6480464 Ivermectin results in decreased expression of GSS protein CTD PMID:32959892 Gss Rat lead diacetate increases expression ISO Gss (Mus musculus) 6480464 lead acetate results in increased expression of GSS mRNA CTD PMID:25270620 Gss Rat leflunomide increases expression EXP 6480464 leflunomide results in increased expression of GSS mRNA CTD PMID:24136188 Gss Rat lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [methylmercuric chloride results in decreased activity of GSS protein] CTD PMID:32061141 Gss Rat lithocholic acid affects expression ISO GSS (Homo sapiens) 6480464 Lithocholic Acid affects the expression of GSS mRNA and Lithocholic Acid affects the expression of GSS protein CTD PMID:20146260 Gss Rat lithocholic acid multiple interactions ISO GSS (Homo sapiens) 6480464 S-Adenosylmethionine inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA] more ... CTD PMID:20146260 Gss Rat LY294002 multiple interactions ISO GSS (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ursodeoxycholic Acid results in increased expression of GSS mRNA] CTD PMID:19073151 Gss Rat LY294002 decreases expression ISO GSS (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of GSS mRNA CTD PMID:19073151 Gss Rat lycopene multiple interactions ISO Gss (Mus musculus) 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSS mRNA] CTD PMID:35917956 and PMID:36610486 Gss Rat mercaptopurine increases expression ISO GSS (Homo sapiens) 6480464 Mercaptopurine results in increased expression of GSS mRNA CTD PMID:18222062 Gss Rat mercury atom affects abundance ISO GSS (Homo sapiens) 6480464 GSS gene polymorphism affects the abundance of Mercury CTD PMID:21967774 Gss Rat mercury(0) affects abundance ISO GSS (Homo sapiens) 6480464 GSS gene polymorphism affects the abundance of Mercury CTD PMID:21967774 Gss Rat methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of GSS mRNA CTD PMID:15890375 Gss Rat methidathion increases expression ISO Gss (Mus musculus) 6480464 methidathion results in increased expression of GSS mRNA CTD PMID:34813904 Gss Rat methyl methanesulfonate increases expression ISO GSS (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of GSS mRNA CTD PMID:23649840 Gss Rat methylmercury chloride increases expression ISO Gss (Mus musculus) 6480464 methylmercuric chloride results in increased expression of GSS mRNA CTD PMID:20061341 Gss Rat methylmercury chloride decreases activity EXP 6480464 methylmercuric chloride results in decreased activity of GSS protein CTD PMID:32061141 Gss Rat methylmercury chloride multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [methylmercuric chloride results in decreased activity of GSS protein] CTD PMID:32061141 Gss Rat methylmercury chloride increases expression ISO GSS (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of GSS protein CTD PMID:27180086 Gss Rat microcystin-LR increases expression ISO Gss (Mus musculus) 6480464 cyanoginosin LR results in increased expression of GSS mRNA CTD PMID:17654400 and PMID:37342990 Gss Rat misonidazole increases response to substance ISO GSS (Homo sapiens) 6480464 GSS gene mutant form results in increased susceptibility to Misonidazole CTD PMID:3874843 Gss Rat N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in decreased methylation of GSS gene CTD PMID:33148267 Gss Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO Gss (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSS mRNA CTD PMID:20061341 Gss Rat N-methyl-N'-nitro-N-nitrosoguanidine decreases expression ISO GSS (Homo sapiens) 6480464 Methylnitronitrosoguanidine results in decreased expression of GSS mRNA CTD PMID:12634122 Gss Rat N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of GSS mRNA CTD PMID:19638242 Gss Rat N-nitrosodiethylamine increases expression ISO Gss (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of GSS mRNA CTD PMID:35523338 Gss Rat N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of GSS mRNA CTD PMID:15890375 Gss Rat N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of GSS protein CTD PMID:19716841 Gss Rat naphthalene decreases expression ISO Gss (Mus musculus) 6480464 naphthalene results in decreased expression of GSS mRNA CTD PMID:31020322 Gss Rat nefazodone increases expression EXP 6480464 nefazodone results in increased expression of GSS mRNA CTD PMID:24136188 Gss Rat nimesulide increases expression EXP 6480464 nimesulide results in increased expression of GSS mRNA CTD PMID:24136188 Gss Rat nitrogen dioxide decreases expression EXP 6480464 Nitrogen Dioxide results in decreased expression of GSS mRNA CTD PMID:16049373 Gss Rat Nutlin-3 multiple interactions ISO GSS (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of and results in increased secretion of GSS protein CTD PMID:38460933 Gss Rat ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of GSS mRNA CTD PMID:12700408 more ... Gss Rat oligopeptide increases activity ISO Gss (Mus musculus) 6480464 Oligopeptides results in increased activity of GSS protein CTD PMID:23796539 Gss Rat ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of GSS mRNA and [Ozone co-treated with Chlorine] results in decreased expression of GSS mRNA CTD PMID:18636392 and PMID:37047376 Gss Rat ozone increases expression EXP 6480464 Ozone results in increased expression of GSS mRNA CTD PMID:32991914 Gss Rat paracetamol multiple interactions ISO Gss (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of GSS mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GSS mRNA] CTD PMID:17585979 Gss Rat paracetamol increases expression ISO Gss (Mus musculus) 6480464 Acetaminophen results in increased expression of GSS mRNA CTD PMID:25499718 Gss Rat paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of GSS protein CTD PMID:16687475 Gss Rat paracetamol affects expression ISO Gss (Mus musculus) 6480464 Acetaminophen affects the expression of GSS mRNA CTD PMID:17562736 Gss Rat paraoxon increases expression ISO GSS (Homo sapiens) 6480464 Paraoxon results in increased expression of GSS CTD PMID:24486155 Gss Rat paraquat increases expression ISO Gss (Mus musculus) 6480464 Paraquat results in increased expression of GSS mRNA CTD PMID:31216030 Gss Rat paraquat increases expression EXP 6480464 Paraquat results in increased expression of GSS mRNA CTD PMID:32680482 Gss Rat paraquat multiple interactions ISO Gss (Mus musculus) 6480464 SIRT6 promotes the reaction [Paraquat results in increased expression of GSS mRNA] CTD PMID:31216030 Gss Rat pentachlorophenol increases expression ISO Gss (Mus musculus) 6480464 Pentachlorophenol results in increased expression of GSS mRNA CTD PMID:23892564 Gss Rat perfluorohexanesulfonic acid increases expression ISO Gss (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of GSS mRNA CTD PMID:37995155 Gss Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Gss (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GSS mRNA CTD PMID:36331819 Gss Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of GSS mRNA CTD PMID:19162173 Gss Rat permethrin multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in decreased methylation of GSS gene CTD PMID:33148267 Gss Rat phenobarbital affects expression ISO Gss (Mus musculus) 6480464 Phenobarbital affects the expression of GSS mRNA CTD PMID:23091169 Gss Rat PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of GSS mRNA CTD PMID:12376462 Gss Rat piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of GSS mRNA CTD PMID:15890375 and PMID:22484513 Gss Rat pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of GSS mRNA CTD PMID:15890375 Gss Rat pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of GSS mRNA CTD PMID:16940010 Gss Rat purine-6-thiol increases expression ISO GSS (Homo sapiens) 6480464 Mercaptopurine results in increased expression of GSS mRNA CTD PMID:18222062 Gss Rat quercetin increases expression ISO Gss (Mus musculus) 6480464 Quercetin results in increased expression of GSS mRNA CTD PMID:19183254 Gss Rat resveratrol multiple interactions ISO GSS (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of GSS mRNA more ... CTD PMID:23557933 and PMID:37419272 Gss Rat resveratrol increases expression ISO GSS (Homo sapiens) 6480464 Resveratrol results in increased expression of GSS mRNA CTD PMID:37419272 Gss Rat rotenone increases expression ISO Gss (Mus musculus) 6480464 Rotenone results in increased expression of GSS mRNA CTD PMID:23186747 Gss Rat S-adenosyl-L-methioninate multiple interactions ISO GSS (Homo sapiens) 6480464 S-Adenosylmethionine inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA] and S-Adenosylmethionine promotes the reaction [Ursodeoxycholic Acid inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA]] CTD PMID:20146260 Gss Rat S-adenosyl-L-methionine multiple interactions ISO GSS (Homo sapiens) 6480464 S-Adenosylmethionine inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA] and S-Adenosylmethionine promotes the reaction [Ursodeoxycholic Acid inhibits the reaction [Lithocholic Acid affects the expression of GSS mRNA]] CTD PMID:20146260 Gss Rat S-butyl-DL-homocysteine (S,R)-sulfoximine decreases activity EXP 6480464 Buthionine Sulfoximine results in decreased activity of GSS protein CTD PMID:10904027 Gss Rat S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression EXP 6480464 Buthionine Sulfoximine results in increased expression of GSS mRNA CTD PMID:10978506 Gss Rat SB 431542 multiple interactions ISO GSS (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of GSS protein CTD PMID:37664457 Gss Rat sodium arsenite decreases expression ISO GSS (Homo sapiens) 6480464 sodium arsenite results in decreased expression of GSS mRNA CTD PMID:12634122 and PMID:37956786 Gss Rat sodium arsenite increases expression ISO GSS (Homo sapiens) 6480464 sodium arsenite results in increased expression of GSS mRNA CTD PMID:32066060 Gss Rat sodium fluoride decreases expression ISO Gss (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of GSS protein CTD PMID:28918527 Gss Rat sunitinib increases expression ISO Gss (Mus musculus) 6480464 sunitinib results in increased expression of GSS mRNA CTD PMID:30031043 Gss Rat T-2 toxin affects expression EXP 6480464 T-2 Toxin affects the expression of GSS protein CTD PMID:26141394 Gss Rat T-2 toxin increases expression ISO GSS (Homo sapiens) 6480464 T-2 Toxin results in increased expression of GSS mRNA CTD PMID:34581912 Gss Rat tetrachloromethane increases expression ISO Gss (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of GSS mRNA CTD PMID:27339419 more ... Gss Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of GSS mRNA CTD PMID:31150632 Gss Rat tetrachloromethane multiple interactions ISO Gss (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of GSS mRNA CTD PMID:30517762 Gss Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of GSS mRNA CTD PMID:10978506 Gss Rat titanium dioxide multiple interactions ISO Gss (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GSS mRNA CTD PMID:29950665 Gss Rat titanium dioxide decreases methylation ISO Gss (Mus musculus) 6480464 titanium dioxide results in decreased methylation of GSS promoter CTD PMID:35295148 Gss Rat toluene affects expression EXP 6480464 Toluene affects the expression of GSS mRNA CTD PMID:18653662 Gss Rat triclosan affects expression ISO GSS (Homo sapiens) 6480464 Triclosan affects the expression of GSS mRNA CTD PMID:31714634 Gss Rat triptonide decreases expression ISO Gss (Mus musculus) 6480464 triptonide results in decreased expression of GSS mRNA CTD PMID:33045310 Gss Rat tris(2-butoxyethyl) phosphate increases expression ISO Gss (Mus musculus) 6480464 tris(2-butoxyethyl) phosphate results in increased expression of GSS mRNA CTD PMID:25808963 Gss Rat trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of GSS mRNA CTD PMID:24136188 Gss Rat ursodeoxycholic acid multiple interactions ISO GSS (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ursodeoxycholic Acid results in increased expression of GSS mRNA] more ... CTD PMID:19073151 and PMID:20146260 Gss Rat ursodeoxycholic acid increases expression ISO GSS (Homo sapiens) 6480464 Ursodeoxycholic Acid results in increased expression of GSS mRNA CTD PMID:19073151 Gss Rat valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of GSS mRNA CTD PMID:24136188 Gss Rat valproic acid affects expression ISO GSS (Homo sapiens) 6480464 Valproic Acid affects the expression of GSS mRNA CTD PMID:25979313 Gss Rat valproic acid decreases expression ISO GSS (Homo sapiens) 6480464 Valproic Acid results in decreased expression of GSS mRNA CTD PMID:28001369 Gss Rat vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of GSS gene CTD PMID:31079544 Gss Rat zinc oxide multiple interactions ISO Gss (Mus musculus) 6480464 Zinc Oxide affects the splicing of and results in increased expression of GSS mRNA CTD PMID:30500950
Imported Annotations - SMPDB
Imported Annotations - KEGG (archival)
(-)-epigallocatechin 3-gallate (ISO) (-)-quinic acid (ISO) (1->4)-beta-D-glucan (ISO) (R)-lipoic acid (EXP) 1,2-dimethylhydrazine (EXP,ISO) 1,4-benzoquinone (ISO) 1-naphthyl isothiocyanate (EXP) 17alpha-ethynylestradiol (EXP,ISO) 17beta-estradiol (EXP,ISO) 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO) 1H-pyrazole (ISO) 2,2',4,4',5,5'-hexachlorobiphenyl (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4,6-trinitrotoluene (EXP) 2,4-dinitrotoluene (EXP) 2,6-dinitrotoluene (EXP) 2-acetamidofluorene (ISO) 2-nitrofluorene (EXP) 2-tert-butylhydroquinone (EXP,ISO) 3,3',4,4',5-pentachlorobiphenyl (EXP) 3,7-dihydropurine-6-thione (ISO) 3-chloropropane-1,2-diol (EXP) 3-methylcholanthrene (ISO) 3H-1,2-dithiole-3-thione (EXP) 4,4'-diaminodiphenylmethane (ISO) 4,4'-sulfonyldiphenol (ISO) 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (EXP) 4-amino-2,6-dinitrotoluene (EXP) 4-hydroxynon-2-enal (ISO) 6-propyl-2-thiouracil (EXP) 7,12-dimethyltetraphene (EXP) acrylamide (EXP) actinomycin D (ISO) aflatoxin B1 (EXP,ISO) all-trans-retinoic acid (ISO) alpha-D-galactose (ISO) ammonium chloride (EXP) Anetholtrithion (ISO) arecoline (ISO) aristolochic acid A (ISO) arsane (ISO) arsenic atom (ISO) azathioprine (ISO) Azoxymethane (ISO) benzo[a]pyrene (ISO) beta-lapachone (ISO) bis(2-chloroethyl) sulfide (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) Bisphenol B (ISO) bisphenol F (ISO) butan-1-ol (ISO) cadmium dichloride (ISO) cadmium sulfide (ISO) celecoxib (ISO) chloroprene (ISO) chlorpyrifos (EXP) cisplatin (ISO) clofibrate (ISO) cobalt dichloride (ISO) copper atom (EXP,ISO) copper(0) (EXP,ISO) copper(II) sulfate (ISO) Cuprizon (EXP) curcumin (ISO) deoxynivalenol (ISO) dextran sulfate (ISO) dibutyl phthalate (EXP) dichlorine (EXP) diethyl malate (ISO) diethyl maleate (EXP) diethylstilbestrol (EXP) diquat (ISO) enilconazole (ISO) erdosteine (ISO) ethanol (ISO) ethyl methanesulfonate (ISO) fenamidone (ISO) fenthion (ISO) flutamide (EXP) folic acid (ISO) formaldehyde (ISO) fulvestrant (ISO) furan (EXP) galactose (ISO) genistein (ISO) gentamycin (EXP) glafenine (EXP) glutathione (ISO) Glutathione ethyl ester (ISO) Hexachloro-1,3-butadiene (EXP) hydrogen peroxide (ISO) hydroquinone (ISO) hypochlorous acid (ISO) indometacin (EXP) iron atom (ISO) iron(0) (ISO) isoflurane (ISO) ivermectin (ISO) lead diacetate (ISO) leflunomide (EXP) lipoic acid (EXP) lithocholic acid (ISO) LY294002 (ISO) lycopene (ISO) mercaptopurine (ISO) mercury atom (ISO) mercury(0) (ISO) methapyrilene (EXP) methidathion (ISO) methyl methanesulfonate (ISO) methylmercury chloride (EXP,ISO) microcystin-LR (ISO) misonidazole (ISO) N,N-diethyl-m-toluamide (EXP) N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO) N-methyl-N'-nitro-N-nitrosoguanidine (ISO) N-nitrosodiethylamine (EXP,ISO) N-nitrosodimethylamine (EXP) N-nitrosomorpholine (EXP) naphthalene (ISO) nefazodone (EXP) nimesulide (EXP) nitrogen dioxide (EXP) Nutlin-3 (ISO) ochratoxin A (EXP) oligopeptide (ISO) ozone (EXP) paracetamol (EXP,ISO) paraoxon (ISO) paraquat (EXP,ISO) pentachlorophenol (ISO) perfluorohexanesulfonic acid (ISO) perfluorooctane-1-sulfonic acid (ISO) perfluorooctanoic acid (EXP) permethrin (EXP) phenobarbital (ISO) PhIP (EXP) piperonyl butoxide (EXP) pirinixic acid (EXP) purine-6-thiol (ISO) quercetin (ISO) resveratrol (ISO) rotenone (ISO) S-adenosyl-L-methioninate (ISO) S-adenosyl-L-methionine (ISO) S-butyl-DL-homocysteine (S,R)-sulfoximine (EXP) SB 431542 (ISO) sodium arsenite (ISO) sodium fluoride (ISO) sunitinib (ISO) T-2 toxin (EXP,ISO) tetrachloromethane (EXP,ISO) thioacetamide (EXP) titanium dioxide (ISO) toluene (EXP) triclosan (ISO) triptonide (ISO) tris(2-butoxyethyl) phosphate (ISO) trovafloxacin (EXP) ursodeoxycholic acid (ISO) valdecoxib (EXP) valproic acid (ISO) vinclozolin (EXP) zinc oxide (ISO)
Molecular Function
ATP binding (IDA,IEA,ISO,ISS) glutathione binding (IBA,IDA,IEA,ISO,ISS) glutathione synthase activity (IBA,IDA,IEA,ISO) glycine binding (IDA) identical protein binding (IEA,IPI,ISO) ligase activity (IEA) magnesium ion binding (IEA,ISO,ISS) metal ion binding (IEA) nucleotide binding (IEA) peptide binding (IPI) protein binding (ISO) protein homodimerization activity (IEA,ISO,ISS)
1.
Glutathione synthesis in normal liver and in Yoshida AH-130 hepatoma.
Biocca ME, etal., Toxicol Pathol. 1986;14(4):415-6.
2.
Missense mutations in the human glutathione synthetase gene result in severe metabolic acidosis, 5-oxoprolinuria, hemolytic anemia and neurological dysfunction.
Dahl N, etal., Hum Mol Genet 1997 Jul;6(7):1147-52.
3.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
5.
Effects of chondroitin sulfate on alteration of actin cytoskeleton in rats with acute necrotizing pancreatitis.
He ZY and Guo RX, Hepatobiliary Pancreat Dis Int. 2007 Oct;6(5):537-43.
6.
Amino acid sequence of rat kidney glutathione synthetase.
Huang CS, etal., Proc Natl Acad Sci U S A 1995 Feb 14;92(4):1232-6.
7.
High fat feeding and dietary L-arginine supplementation differentially regulate gene expression in rat white adipose tissue.
Jobgen W, etal., Amino Acids. 2009 May;37(1):187-98. Epub 2009 Feb 12.
8.
KEGG: Kyoto Encyclopedia of Genes and Genomes
KEGG
9.
Coordinated changes in xenobiotic metabolizing enzyme gene expression in aging male rats.
Lee JS, etal., Toxicol Sci. 2008 Nov;106(1):263-83. Epub 2008 Jul 24.
10.
Gender differences in glutathione metabolism in Alzheimer's disease.
Liu H, etal., J Neurosci Res. 2005 Mar 15;79(6):861-7.
11.
Novel kinetics of mammalian glutathione synthetase: characterization of gamma-glutamyl substrate cooperative binding.
Luo JL, etal., Biochem Biophys Res Commun. 2000 Aug 28;275(2):577-81.
12.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
13.
OMIM Disease Annotation Pipeline
OMIM Disease Annotation Pipeline
14.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
15.
SMPDB Annotation Import Pipeline
Pipeline to import SMPDB annotations from SMPDB into RGD
16.
GOA pipeline
RGD automated data pipeline
17.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
19.
Mutations in the glutathione synthetase gene cause 5-oxoprolinuria.
Shi ZZ, etal., Nat Genet. 1996 Nov;14(3):361-5.
20.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
21.
Tentative Sequence Identification Numbers
Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
22.
A spectrophotometric assay of gamma-glutamylcysteine synthetase and glutathione synthetase in crude extracts from tissues and cultured mammalian cells.
Volohonsky G, etal., Chem Biol Interact. 2002 Apr 20;140(1):49-65.
23.
Tumour necrosis factor alpha induces co-ordinated activation of rat GSH synthetic enzymes via nuclear factor kappaB and activator protein-1.
Yang H, etal., Biochem J. 2005 Oct 15;391(Pt 2):399-408.
24.
Role of AP-1 in the coordinate induction of rat glutamate-cysteine ligase and glutathione synthetase by tert-butylhydroquinone.
Yang H, etal., J Biol Chem 2002 Sep 20;277(38):35232-9.
Gss Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 164,508,005 - 164,538,343 (-) NCBI GRCr8 mRatBN7.2 3 144,047,849 - 144,078,197 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 144,047,850 - 144,078,198 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 3 147,914,375 - 147,944,469 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 156,531,652 - 156,561,750 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 154,271,186 - 154,301,288 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 3 151,076,254 - 151,106,557 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 151,076,254 - 151,106,557 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 157,443,738 - 157,474,042 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 146,057,517 - 146,087,820 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 3 145,963,138 - 145,993,442 (-) NCBI Celera 3 142,772,407 - 142,802,700 (-) NCBI Celera Cytogenetic Map 3 q42 NCBI
GSS Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 20 34,928,432 - 34,956,027 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 20 34,928,432 - 34,956,027 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 20 33,516,235 - 33,543,830 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 20 32,979,897 - 33,007,262 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 20 32,979,897 - 33,007,262 NCBI Celera 20 30,265,329 - 30,292,695 (-) NCBI Celera Cytogenetic Map 20 q11.22 NCBI HuRef 20 30,294,556 - 30,321,979 (-) NCBI HuRef CHM1_1 20 33,417,456 - 33,444,826 (-) NCBI CHM1_1 T2T-CHM13v2.0 20 36,649,086 - 36,676,682 (-) NCBI T2T-CHM13v2.0
Gss Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 2 155,405,101 - 155,434,730 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 2 155,405,101 - 155,434,730 (-) Ensembl GRCm39 Ensembl GRCm38 2 155,563,181 - 155,592,810 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 2 155,563,181 - 155,592,810 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 2 155,388,919 - 155,418,442 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 2 155,254,624 - 155,284,147 (-) NCBI MGSCv36 mm8 Celera 2 161,495,432 - 161,524,969 (-) NCBI Celera Cytogenetic Map 2 H1 NCBI cM Map 2 77.26 NCBI
Gss Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955422 26,427,581 - 26,463,781 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955422 26,427,581 - 26,483,380 (+) NCBI ChiLan1.0 ChiLan1.0
GSS Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 21 40,661,205 - 40,688,813 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 20 40,654,308 - 40,682,219 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 20 31,256,734 - 31,284,356 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 20 32,381,745 - 32,409,327 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 20 32,381,745 - 32,409,297 (-) Ensembl panpan1.1 panPan2
GSS Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 24 23,973,807 - 24,000,281 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 24 23,901,045 - 23,997,286 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 24 23,619,971 - 23,646,466 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 24 24,665,657 - 24,692,375 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 24 24,665,043 - 24,692,288 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 24 23,952,937 - 23,979,420 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 24 24,048,251 - 24,074,736 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 24 24,487,171 - 24,513,688 (-) NCBI UU_Cfam_GSD_1.0
Gss Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024408640 172,955,595 - 172,983,992 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936561 5,765,610 - 5,793,567 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936561 5,765,637 - 5,793,951 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
GSS Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 17 38,312,720 - 38,342,298 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 17 38,316,199 - 38,342,253 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 17 43,511,098 - 43,539,281 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
GSS Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 2 39,230,629 - 39,258,511 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 2 39,230,487 - 39,254,648 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666050 87,554,278 - 87,582,240 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Gss
.
Predicted Target Of
Count of predictions: 82 Count of miRNA genes: 69 Interacting mature miRNAs: 78 Transcripts: ENSRNOT00000025657 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
2312673 Scl63 Serum cholesterol level QTL 63 0.001 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 3 98535255 168026850 Rat 1598877 Bp285 Blood pressure QTL 285 1.5 0.03 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 120538241 165538241 Rat 1578653 Vnigr3 Vascular neointimal growth QTL 3 3.1 artery morphology trait (VT:0002191) artery neointimal hyperplastic lesion area (CMO:0001414) 3 130656562 169034231 Rat 2302373 Gluco39 Glucose level QTL 39 5.01 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 3 98535386 161695835 Rat 1298068 Bp167 Blood pressure QTL 167 0.004 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 141074471 169034231 Rat 70216 Cm14 Cardiac mass QTL 14 2.1 heart mass (VT:0007028) heart wet weight (CMO:0000069) 3 31172320 163586636 Rat 2292591 Esta4 Estrogen-induced thymic atrophy QTL 4 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 3 47233211 147415807 Rat 2298477 Eau4 Experimental allergic uveoretinitis QTL 4 0.0011 uvea integrity trait (VT:0010551) experimental autoimmune uveitis score (CMO:0001504) 3 137398739 169034231 Rat 61335 Bp20 Blood pressure QTL 20 3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 141339236 155617360 Rat 1581568 Rf53 Renal function QTL 53 urine total protein amount (VT:0000032) urine protein excretion rate to body weight ratio (CMO:0001099) 3 56395968 161299569 Rat 1578754 Stresp16 Stress response QTL 16 4 0.001 blood renin amount (VT:0003349) plasma renin activity level (CMO:0000116) 3 112681431 157681431 Rat 1331726 Bp208 Blood pressure QTL 208 3.129 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 141339013 162184794 Rat 1300173 Rf11 Renal function QTL 11 3.38 renal blood flow trait (VT:2000006) absolute change in renal blood flow rate (CMO:0001168) 3 121056165 145956249 Rat 9589106 Insul23 Insulin level QTL 23 13.86 0.001 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 3 131635904 169034231 Rat 10755461 Coatc16 Coat color QTL 16 coat/hair pigmentation trait (VT:0010463) pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812) 3 122438700 167438700 Rat 8662816 Vetf4 Vascular elastic tissue fragility QTL 4 4 renal artery integrity trait (VT:0010642) number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563) 3 59242096 157323038 Rat 1559282 Emca5 Estrogen-induced mammary cancer QTL 5 3.9 mammary gland integrity trait (VT:0010552) percentage of study population developing mammary tumors during a period of time (CMO:0000948) 3 43827364 169034231 Rat 2303620 Vencon4 Ventilatory control QTL 4 3.9 respiration trait (VT:0001943) tidal volume (CMO:0000222) 3 127162703 168026850 Rat 631841 Niddm39 Non-insulin dependent diabetes mellitus QTL 39 3.36 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 3 94856903 159898684 Rat 1576306 Schws3 Schwannoma susceptibility QTL 3 0.001 nervous system integrity trait (VT:0010566) percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017) 3 118839124 163839124 Rat 619618 Rf3 Renal disease susceptibility QTL 3 6.5 0.001 urine albumin amount (VT:0002871) urine albumin excretion rate to body weight ratio (CMO:0001270) 3 107693393 152693393 Rat 1300159 Kidm4 Kidney mass QTL 4 3.83 kidney mass (VT:0002707) right kidney wet weight to body weight ratio (CMO:0001953) 3 121056165 157309487 Rat 5686842 Rf59 Renal function QTL 59 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 3 140069424 146976080 Rat 2301971 Cm71 Cardiac mass QTL 71 4.63 heart left ventricle mass (VT:0007031) heart left ventricle weight (CMO:0000776) 3 41874578 155617519 Rat 2312659 Slep7 Serum leptin concentration QTL 7 0.001 blood leptin amount (VT:0005667) serum leptin level (CMO:0000780) 3 98535255 168026850 Rat 631673 Iddm13 Insulin dependent diabetes mellitus QTL 13 1.3 0.663 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 3 130193298 161695983 Rat 2301970 Bw81 Body weight QTL 81 5.19 body mass (VT:0001259) body weight (CMO:0000012) 3 41874578 155617519 Rat 1581546 Pur13 Proteinuria QTL 13 2.93 0.0335 urine total protein amount (VT:0000032) urine protein excretion rate (CMO:0000759) 3 78196190 146592722 Rat 1578656 Vnigr2 Vascular neointimal growth QTL 2 4.2 artery morphology trait (VT:0002191) lesioned artery residual lumen area (CMO:0001417) 3 130656562 169034231 Rat 8552952 Pigfal13 Plasma insulin-like growth factor 1 level QTL 13 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 3 138799500 169034231 Rat 631541 Bp81 Blood pressure QTL 81 4 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 124122556 169034231 Rat 2293087 Iddm27 Insulin dependent diabetes mellitus QTL 27 2.68 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 3 97551417 147415807 Rat 2312670 Bw94 Body weight QTL 94 0.01 inguinal fat pad mass (VT:0010424) inguinal fat pad weight to body weight ratio (CMO:0001253) 3 98535255 168026850 Rat
D3Got112
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 144,050,848 - 144,051,023 (+) MAPPER mRatBN7.2 Rnor_6.0 3 151,079,253 - 151,079,427 NCBI Rnor6.0 Rnor_5.0 3 157,446,738 - 157,446,912 UniSTS Rnor5.0 RGSC_v3.4 3 146,060,515 - 146,060,690 RGD RGSC3.4 RGSC_v3.4 3 146,060,516 - 146,060,690 UniSTS RGSC3.4 RGSC_v3.1 3 145,966,138 - 145,966,312 RGD Celera 3 142,775,406 - 142,775,580 UniSTS RH 3.4 Map 3 1298.6 RGD RH 3.4 Map 3 1298.6 UniSTS Cytogenetic Map 3 q42 UniSTS
RH127607
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 144,048,021 - 144,048,222 (+) MAPPER mRatBN7.2 Rnor_6.0 3 151,076,426 - 151,076,626 NCBI Rnor6.0 Rnor_5.0 3 157,443,911 - 157,444,111 UniSTS Rnor5.0 RGSC_v3.4 3 146,057,689 - 146,057,889 UniSTS RGSC3.4 Celera 3 142,772,579 - 142,772,779 UniSTS RH 3.4 Map 3 1305.9 UniSTS Cytogenetic Map 3 q42 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000025657 ⟹ ENSRNOP00000025657
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 144,047,852 - 144,078,198 (-) Ensembl Rnor_6.0 Ensembl 3 151,076,254 - 151,106,557 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000115033 ⟹ ENSRNOP00000094043
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 144,047,850 - 144,078,028 (-) Ensembl
RefSeq Acc Id:
NM_012962 ⟹ NP_037094
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 164,508,005 - 164,538,306 (-) NCBI mRatBN7.2 3 144,047,850 - 144,078,154 (-) NCBI Rnor_6.0 3 151,076,254 - 151,106,557 (-) NCBI Rnor_5.0 3 157,443,738 - 157,474,042 (-) NCBI RGSC_v3.4 3 146,057,517 - 146,087,820 (-) RGD Celera 3 142,772,407 - 142,802,700 (-) RGD
Sequence:
TGGAGTTTGAGCTTGGCGAGCAGCTGGACAACGAGCGAGTTGGGATGGCCACCAGCTGGGGAAGCATCTTGCAGGATGAGAAGCAGCTGGAAGAGTTGGCACAGCAGGCCATAGACCGGGCCCTGGCT
hide sequence
RefSeq Acc Id:
XM_039104373 ⟹ XP_038960301
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 164,508,007 - 164,538,343 (-) NCBI mRatBN7.2 3 144,047,849 - 144,078,197 (-) NCBI
RefSeq Acc Id:
NP_037094 ⟸ NM_012962
- UniProtKB:
P46413 (UniProtKB/Swiss-Prot), A6KI44 (UniProtKB/TrEMBL), A0A8I6AYD3 (UniProtKB/TrEMBL)
- Sequence:
MATSWGSILQDEKQLEELAQQAIDRALAEGVLLRSAKNPSSSDVVTYAPFTLFPSPVPSTLLEQAYAVQMDFNILVDAVSQNSAFLEQTLSSTIKKDEYTARLFDIYKQVLKEGIAQTVFLGLNRSDY
hide sequence
Ensembl Acc Id:
ENSRNOP00000025657 ⟸ ENSRNOT00000025657
RefSeq Acc Id:
XP_038960301 ⟸ XM_039104373
- Peptide Label:
isoform X1
- UniProtKB:
A6KI45 (UniProtKB/TrEMBL), A0A8I6AYD3 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSRNOP00000094043 ⟸ ENSRNOT00000115033
RGD ID: 13692585 Promoter ID: EPDNEW_R3110 Type: initiation region Name: Gss_1 Description: glutathione synthetase SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 3 151,106,540 - 151,106,600 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2002-06-10
Gss
glutathione synthetase
Name updated
70584 APPROVED
Note Type
Note
Reference
gene_expression
mRNA and enzyme are detected in kidney
69853
