Gapdh (glyceraldehyde-3-phosphate dehydrogenase) - Rat Genome Database

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Gene: Gapdh (glyceraldehyde-3-phosphate dehydrogenase) Rattus norvegicus
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Symbol: Gapdh (Ensembl: Gapdhl3)
Name: glyceraldehyde-3-phosphate dehydrogenase (Ensembl:glyceraldehyde-3-phosphate dehydrogenase like 3)
RGD ID: 2661
Description: Enables several functions, including glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; identical protein binding activity; and peptidyl-cysteine S-nitrosylase activity. Involved in several processes, including gluconeogenesis; intracellular signaling cassette; and negative regulation of vascular associated smooth muscle cell apoptotic process. Located in cytosol; microtubule cytoskeleton; and nucleus. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Used to study Alzheimer's disease and middle cerebral artery infarction. Biomarker of several diseases, including brain glioma; diabetic retinopathy; obesity; oral squamous cell carcinoma; and rheumatic heart disease. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDH (glyceraldehyde-3-phosphate dehydrogenase); PARTICIPATES IN gluconeogenesis pathway; electron transport chain pathway; Fanconi syndrome pathway; INTERACTS WITH (-)-selegiline; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 38 kDa BFA-dependent ADP-ribosylation substrate; BARS-38; Gapd; peptidyl-cysteine S-nitrosylase GAPDH
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gapdh-ps1   Gapdh-ps118   Gapdh-ps119   Gapdh-ps2   Gapdh-ps36   Gapdh-ps49  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,648,592 - 159,653,436 (-)NCBIGRCr8
mRatBN7.24157,962,312 - 157,967,158 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,962,343 - 157,966,235 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.04157,676,336 - 157,680,322 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,693,580 - 224,697,455 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44161,282,215 - 161,286,090 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4146,699,388 - 146,703,263 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Original Reference(s)
GapdhRatAlzheimer's disease onsetISOGAPDH (Homo sapiens)1358618DNA:snps:5' utr more ...RGD 
GapdhRatAlzheimer's disease  ISOGAPDH (Homo sapiens)13792604 RGD 
GapdhRatAlzheimer's disease  ISOGapdh (Mus musculus)13792614protein:decreased activity:cerebral cortex and cerebellumRGD 
GapdhRatAlzheimer's disease susceptibilityISOGAPDH (Homo sapiens)13792611DNA:SNP:5' utr:rs3741916 (human)RGD 
GapdhRatAlzheimer's disease  ISOGAPDH (Homo sapiens)13792613protein:increased S-glutathionylation and decreased activity:inferior parietal cortexRGD 
GapdhRatAlzheimer's disease  ISOGAPDH (Homo sapiens)13792612DNA:SNPs more ...RGD 
GapdhRatAlzheimer's disease  IDA 13792614protein:decreased activity:cerebral cortex and hippocampusRGD 
GapdhRatbrain glioma  IEP 13792685 RGD 
GapdhRatCOVID-19  ISOGAPDH (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
GapdhRatdiabetic retinopathy  IEP 2315975associated with Diabetes Mellitus and ExperimentalRGD 
GapdhRatepilepsy  IEP 13792618 RGD 
GapdhRatExperimental Diabetes Mellitus treatmentIEP 13792671 RGD 
GapdhRatHuntington's disease  ISOGapdh (Mus musculus)13792684 RGD 
GapdhRatlymphangioleiomyomatosis  ISOGAPDH (Homo sapiens)152995523protein:increased expression:lung (human)RGD 
GapdhRatmiddle cerebral artery infarction  IDA 13792686 RGD 
GapdhRatMyocardial Reperfusion Injury treatmentIEP 11574725 RGD 
GapdhRatobesity treatmentIEP 13792668 RGD 
GapdhRatoral squamous cell carcinoma  IEP 13792673 RGD 
GapdhRatPregnancy in Diabetics  IEP 2315979associated with Diabetes Mellitus more ...RGD 
GapdhRatrheumatic heart disease  IEP 13792679 RGD 
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GapdhRatHyperphosphatemic Familial Tumoral Calcinosis 1  ISOGAPDH (Homo sapiens)8554872ClinVar Annotator: match by term: Tumoral calcinosis more ...ClinVarPMID:25378588 and PMID:29389098
GapdhRatlymphoproliferative syndrome 2  ISOGAPDH (Homo sapiens)8554872ClinVar Annotator: match by term: Lymphoproliferative syndrome 2ClinVarPMID:28492532
GapdhRatperoxisome biogenesis disorder 2B  ISOGAPDH (Homo sapiens)8554872ClinVar Annotator: match by term: Peroxisome biogenesis disorder 2BClinVarPMID:28492532
GapdhRatprimary autosomal recessive microcephaly 21  ISOGAPDH (Homo sapiens)8554872ClinVar Annotator: match by term: Microcephaly 21 more ...ClinVarPMID:25741868
GapdhRatTemtamy syndrome  ISOGAPDH (Homo sapiens)8554872ClinVar Annotator: match by term: Temtamy syndromeClinVarPMID:28492532
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Original Reference(s)
GapdhRatAcute Coronary Syndrome  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21751358
GapdhRatAnimal Disease Models  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27602772
GapdhRatColorectal Neoplasms  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25944804
GapdhRatEsophageal Neoplasms  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15986332
GapdhRathepatocellular carcinoma  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16767786 and PMID:21472284
GapdhRatHypoxia  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19579223
GapdhRatlung adenocarcinoma  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27602772
GapdhRatMouth Neoplasms  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15274141
GapdhRatNecrosis  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: therapeuticCTDPMID:25725130
GapdhRatosteoarthritis  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18784066
GapdhRatosteoporosis  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18924182
GapdhRatParkinsonism  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:29886133
GapdhRatsquamous cell carcinoma  ISOGAPDH (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15274141
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Original Reference(s)
GapdhRat(-)-selegiline multiple interactionsISOGAPDH (Homo sapiens)6480464Selegiline inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of GAPDH mRNA]CTDPMID:14724376
GapdhRat(-)-selegiline multiple interactionsEXP 6480464Selegiline inhibits the reaction [Paraquat affects the localization of GAPDH protein]CTDPMID:20478973
GapdhRat(-)-selegiline multiple interactionsISOGapdh (Mus musculus)6480464Selegiline inhibits the reaction [Hydroxyurea affects the localization of GAPDH protein]CTDPMID:23696560
GapdhRat(1->4)-beta-D-glucan multiple interactionsISOGapdh (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GAPDH mRNACTDPMID:36331819
GapdhRat(S)-nicotine multiple interactionsISOGapdh (Mus musculus)6480464[Nicotine co-treated with 1-Methyl-4-phenyl-1 more ...CTDPMID:20230807
GapdhRat1,10-phenanthroline increases expressionISOGAPDH (Homo sapiens)64804641 and 10-phenanthroline results in increased expression of GAPDH mRNACTDPMID:19502547
GapdhRat1,2-dimethylhydrazine multiple interactionsISOGapdh (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GAPDH mRNACTDPMID:22206623
GapdhRat1,2-naphthoquinone decreases activityISOGAPDH (Homo sapiens)64804641 and 2-naphthoquinone results in decreased activity of GAPDH proteinCTDPMID:21827172
GapdhRat1,2-naphthoquinone affects bindingISOGAPDH (Homo sapiens)64804641 and 2-naphthoquinone binds to GAPDH proteinCTDPMID:21827172
GapdhRat1,2-naphthoquinone multiple interactionsISOGAPDH (Homo sapiens)6480464[Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [1 more ...CTDPMID:21827172
GapdhRat1,3-dinitrobenzene increases oxidationEXP 64804643-dinitrobenzene results in increased oxidation of GAPDH proteinCTDPMID:25716674
GapdhRat1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expressionISOGapdh (Mus musculus)64804641-Methyl-4-phenyl-1 more ...CTDPMID:20230807
GapdhRat1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactionsISOGapdh (Mus musculus)6480464[Caffeine co-treated with 1-Methyl-4-phenyl-1 more ...CTDPMID:20230807
GapdhRat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of GAPDH mRNACTDPMID:10822019 and PMID:17557909
GapdhRat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of GAPDH mRNACTDPMID:32145629
GapdhRat17beta-estradiol decreases expressionISOGapdh (Mus musculus)6480464Estradiol results in decreased expression of GAPDH mRNACTDPMID:39298647
GapdhRat17beta-hydroxy-5alpha-androstan-3-one decreases activityEXP 6480464Dihydrotestosterone results in decreased activity of GAPDH proteinCTDPMID:10650946
GapdhRat17beta-hydroxy-5alpha-androstan-3-one multiple interactionsEXP 6480464nilutamide inhibits the reaction [Dihydrotestosterone results in decreased activity of GAPDH protein]CTDPMID:10650946
GapdhRat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOGapdh (Mus musculus)64804642 more ...CTDPMID:30294300
GapdhRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of GAPDH mRNA and Tetrachlorodibenzodioxin results in increased expression of GAPDH proteinCTDPMID:12361703 and PMID:33387578

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Biological Process
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Original Reference(s)
GapdhRatantimicrobial humoral immune response mediated by antimicrobial peptide involved_inISOGAPDH (Homo sapiens)1624291 PMID:22832495RGDPMID:22832495
GapdhRatapoptotic process involved_inIEAUniProtKB-KW:KW-00531600115GO_REF:0000043UniProtGO_REF:0000043
GapdhRatcAMP/PKA signal transduction  IMP 13792662 RGD 
GapdhRatcanonical glycolysis involved_inISOGapdh (Mus musculus)1624291 PMID:10777777 more ...RGDPMID:10777777 more ...
GapdhRatcellular response to type II interferon involved_inISOGAPDH (Homo sapiens)1624291 PMID:15479637RGDPMID:15479637
GapdhRatfemale pregnancy  IEP 13792674 RGD 
GapdhRatgluconeogenesis  IDA 2302795 RGD 
GapdhRatgluconeogenesis involved_inISOGapdh (Mus musculus)1624291 PMID:28258188RGDPMID:28258188
GapdhRatgluconeogenesis  IMP 13792662 RGD 
GapdhRatglucose metabolic process involved_inIEAInterPro:IPR0064241600115GO_REF:0000002InterProGO_REF:0000002
GapdhRatglycolytic process  IMP 13792662 RGD 
GapdhRatglycolytic process involved_inIBAFB:FBgn0001091 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
GapdhRatglycolytic process involved_inIEAUniProtKB-KW:KW-03241600115GO_REF:0000043UniProtGO_REF:0000043
GapdhRatglycolytic process involved_inIEAUniPathway:UPA001091600115GO_REF:0000041UniProtGO_REF:0000041
GapdhRatimmune system process involved_inIEAUniProtKB-KW:KW-03911600115GO_REF:0000043UniProtGO_REF:0000043
GapdhRatinnate immune response involved_inIEAUniProtKB-KW:KW-03991600115GO_REF:0000043UniProtGO_REF:0000043
GapdhRatmicrotubule cytoskeleton organization involved_inIDA 8553423PMID:15312048UniProt 
GapdhRatnegative regulation of endopeptidase activity involved_inISOGAPDH (Homo sapiens)1624291 PMID:22832495RGDPMID:22832495
GapdhRatnegative regulation of translation involved_inISOGapdh (Mus musculus)1624291 PMID:23071094RGDPMID:23071094
GapdhRatnegative regulation of translation involved_inISOGAPDH (Homo sapiens)1624291 PMID:15479637 and PMID:23071094RGDPMID:15479637 and PMID:23071094
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Cellular Component
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GapdhRatcytoplasm located_inIDA 8553423PMID:15312048UniProt 
GapdhRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
GapdhRatcytoplasm located_inISOGapdh (Mus musculus)1624291 PMID:15159393 more ...RGDPMID:15159393 more ...
GapdhRatcytoplasm located_inISOGAPDH (Homo sapiens)1624291 PMID:11785981 and PMID:24507776RGDPMID:11785981 and PMID:24507776
GapdhRatcytoskeleton located_inIEAUniProtKB-SubCell:SL-00901600115GO_REF:0000044UniProtGO_REF:0000044
GapdhRatcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
GapdhRatcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
GapdhRatcytosol is_active_inISOGapdh (Mus musculus)1624291 PMID:21347706 more ...RGDPMID:21347706 more ...
GapdhRatcytosol located_inISOGapdh (Mus musculus)1624291 PMID:21413931 more ...RGDPMID:21413931 more ...
GapdhRatcytosol is_active_inIBAMGI:95640 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
GapdhRatcytosol part_ofISOGAPDH (Homo sapiens)1624291 PMID:28404743RGDPMID:28404743
GapdhRatcytosol located_inIDA 8554488PMID:15951807UniProt 
GapdhRatcytosol located_inISOGAPDH (Homo sapiens)1624291 PMID:24101517RGDPMID:24101517
GapdhRatcytosol located_inIDA 8553565PMID:19607794UniProt 
GapdhRatcytosol located_inISOGAPDH (Homo sapiens) more ...1624291 RGDGO_REF:0000052
GapdhRatGAIT complex part_ofISOGAPDH (Homo sapiens)1624291 PMID:15479637 and PMID:23071094RGDPMID:15479637 and PMID:23071094
GapdhRatGAIT complex part_ofISOGapdh (Mus musculus)1624291 PMID:23071094RGDPMID:23071094
GapdhRatGAIT complex part_ofISSUniProtKB:P044061600115GO_REF:0000024UniProtGO_REF:0000024
GapdhRatglutamatergic synapse is_active_inIDA 13702148PMID:9371836SynGO 
GapdhRatintracellular membrane-bounded organelle located_inISOGAPDH (Homo sapiens) more ...1624291 RGDGO_REF:0000052
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Molecular Function
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GapdhRataspartic-type endopeptidase inhibitor activity enablesISOGAPDH (Homo sapiens)1624291 PMID:22832495RGDPMID:22832495
GapdhRatdisordered domain specific binding enablesISOGAPDH (Homo sapiens)1624291UniProtKB:P21758 and PMID:11785981RGDPMID:11785981
GapdhRatenzyme binding enablesISOGapdh (Mus musculus)1624291UniProtKB:Q8VCN5 and PMID:19903941RGDPMID:19903941
GapdhRatglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity  IDA 2302795 RGD 
GapdhRatglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity enablesIEAEC:1.2.1.121600115GO_REF:0000003UniProtGO_REF:0000003
GapdhRatglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity enablesIEARHEA:103001600115GO_REF:0000116RHEAGO_REF:0000116
GapdhRatglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity enablesIBACGD:CAL0000197744 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
GapdhRatglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity enablesIDA 8554488PMID:15951807UniProt 
GapdhRatglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity enablesIEAUniRule:UR0000689851600115GO_REF:0000104UniProtGO_REF:0000104
GapdhRatglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity enablesISOGapdh (Mus musculus)1624291MGI:2183515 PMID:15665293 more ...RGDPMID:15665293 more ...
GapdhRatidentical protein binding  IPIGapdh (Rattus norvegicus)11574725homodimerization and homotetramerizationRGD 
GapdhRatidentical protein binding enablesISOGAPDH (Homo sapiens)1624291UniProtKB:P04406 more ...RGDPMID:20392205 and PMID:21988832
GapdhRatmicrotubule binding enablesIDA 8553423PMID:15312048UniProt 
GapdhRatNAD binding enablesIEAUniRule:UR0000689851600115GO_REF:0000104UniProtGO_REF:0000104
GapdhRatNAD binding enablesIEAInterPro:IPR006424 and InterPro:IPR0208281600115GO_REF:0000002InterProGO_REF:0000002
GapdhRatNADP binding enablesIEAInterPro:IPR0064241600115GO_REF:0000002InterProGO_REF:0000002
GapdhRatnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
GapdhRatoxidoreductase activity enablesIEAUniProtKB-KW:KW-05601600115GO_REF:0000043UniProtGO_REF:0000043
GapdhRatoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor enablesIEAInterPro:IPR006424 more ...1600115GO_REF:0000002InterProGO_REF:0000002
GapdhRatpeptidyl-cysteine S-nitrosylase activity enablesIDA 8554381PMID:20972425UniProt 
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RGD Manual Annotations


  
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Original Reference(s)
GapdhRatgluconeogenesis pathway   IDA 2302795 RGD 

Imported Annotations - KEGG (archival)

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Original Reference(s)
GapdhRatAlzheimer's disease pathway   IEA 6907045 KEGGrno:05010
GapdhRatgluconeogenesis pathway   IEA 6907045 KEGGrno:00010
GapdhRatglycolysis pathway   IEA 6907045 KEGGrno:00010
GapdhRatglycolysis/gluconeogenesis pathway  IEA 6907045 KEGGrno:00010

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Reference Title
Reference Citation
1. Association and heterogeneity at the GAPDH locus in Alzheimer's disease. Allen M, etal., Neurobiol Aging. 2012 Jan;33(1):203.e25-33. doi: 10.1016/j.neurobiolaging.2010.08.002. Epub 2010 Sep 23.
2. Interactions among p22, glyceraldehyde-3-phosphate dehydrogenase and microtubules. Andrade J, etal., Biochem J. 2004 Dec 1;384(Pt 2):327-36.
3. Glyceraldehyde-3-phosphate dehydrogenase interacts with phosphorylated Akt resulting from increased blood glucose in rat cardiac muscle. Baba T, etal., FEBS Lett. 2010 Jul 2;584(13):2796-800. doi: 10.1016/j.febslet.2010.05.015. Epub 2010 May 17.
4. Lysine post-translational modification of glyceraldehyde-3-phosphate dehydrogenase regulates hepatic and systemic metabolism. Bond ST, etal., FASEB J. 2017 Jun;31(6):2592-2602. doi: 10.1096/fj.201601215R. Epub 2017 Mar 3.
5. Key enzymes of carbohydrate metabolism as targets of the 11.5-kDa Zn(2+)-binding protein (parathymosin). Brand IA and Heinickel A, J Biol Chem. 1991 Nov 5;266(31):20984-9.
6. Interaction of glyceraldehyde-3-phosphate dehydrogenase in the light-induced rod alpha-transducin translocation. Chen J, etal., J Neurochem. 2008 Mar;104(5):1280-92. Epub 2007 Nov 17.
7. Increased myocardial expression of RAMP1 and RAMP3 in rats with chronic heart failure. Cueille C, etal., Biochem Biophys Res Commun 2002 Jun 7;294(2):340-6.
8. Assessment of GAPDH expression by quantitative real time PCR in blood of Moroccan AD cases. El Kadmiri N, etal., J Clin Neurosci. 2017 Jun;40:24-26. doi: 10.1016/j.jocn.2016.12.007. Epub 2017 Jan 10.
9. Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene. Ercolani L, etal., J Biol Chem 1988 Oct 25;263(30):15335-41.
10. Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Fort P, etal., Nucleic Acids Res 1985 Mar 11;13(5):1431-42.
11. Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC). Foster LJ, etal., J Proteome Res. 2006 Jan;5(1):64-75.
12. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
13. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
14. Spatial profiles of markers of glycolysis, mitochondria, and proton pumps in a rat glioma suggest coordinated programming for proliferation. Grillon E, etal., BMC Res Notes. 2015 Jun 2;8:207. doi: 10.1186/s13104-015-1191-z.
15. S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Hara MR, etal., Nat Cell Biol. 2005 Jul;7(7):665-74. Epub 2005 Jun 12.
16. Nuclear complex of glyceraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidinic endonuclease I protect smooth muscle cells against oxidant-induced cell death. Hou X, etal., FASEB J. 2017 Jul;31(7):3179-3192. doi: 10.1096/fj.201601082R. Epub 2017 Apr 12.
17. Inhibiting a spinal cord signaling pathway protects against ischemia injury in rats. Huo J, etal., J Thorac Cardiovasc Surg. 2018 Jul 30. pii: S0022-5223(18)32035-X. doi: 10.1016/j.jtcvs.2018.07.045.
18. GAPDH/Siah1 cascade is involved in traumatic spinal cord injury and could be attenuated by sivelestat sodium. Huo J, etal., Neuroscience. 2016 Aug 25;330:171-80. doi: 10.1016/j.neuroscience.2016.05.054. Epub 2016 May 30.
19. Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease. Hwang S, etal., EMBO Mol Med. 2015 Oct;7(10):1307-26. doi: 10.15252/emmm.201505256.
20. Identification of major Ca(2+)/calmodulin-dependent protein kinase phosphatase-binding proteins in brain: biochemical analysis of the interaction. Ishida A, etal., Arch Biochem Biophys. 2005 Mar 1;435(1):134-46.
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PMID:3796661   PMID:7144574   PMID:10559001   PMID:11487543   PMID:11785981   PMID:12519789   PMID:12753082   PMID:14651853   PMID:14741744   PMID:15159393   PMID:15479637   PMID:15489334  
PMID:15665293   PMID:16170200   PMID:16418269   PMID:16627065   PMID:16751257   PMID:17426931   PMID:17488287   PMID:17634366   PMID:17962088   PMID:18698006   PMID:18720057   PMID:18837965  
PMID:19022411   PMID:19056867   PMID:19075228   PMID:19131967   PMID:19182904   PMID:19190083   PMID:19199708   PMID:19292454   PMID:19470756   PMID:19723108   PMID:19903941   PMID:19940145  
PMID:19946888   PMID:19950597   PMID:20392205   PMID:20458337   PMID:20518697   PMID:21210726   PMID:21257285   PMID:21362503   PMID:21413931   PMID:21482559   PMID:21539824   PMID:21630459  
PMID:21904640   PMID:21988832   PMID:22252379   PMID:22420779   PMID:22832495   PMID:22871113   PMID:23027902   PMID:23071094   PMID:23106098   PMID:23360709   PMID:23376485   PMID:23527007  
PMID:23530063   PMID:23533145   PMID:23979707   PMID:24101517   PMID:24137001   PMID:24507776   PMID:24670206   PMID:26316108   PMID:26748070   PMID:26945066   PMID:28174179   PMID:28259758  
PMID:29476059   PMID:32438512   PMID:32875725   PMID:33539626   PMID:33546324   PMID:35352799   PMID:35871495   PMID:36755387   PMID:37863305  



Gapdh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,648,592 - 159,653,436 (-)NCBIGRCr8
mRatBN7.24157,962,312 - 157,967,158 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,962,343 - 157,966,235 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.04157,676,336 - 157,680,322 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,693,580 - 224,697,455 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44161,282,215 - 161,286,090 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4146,699,388 - 146,703,263 (-)NCBICelera
Cytogenetic Map4q42NCBI
GAPDH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,534,517 - 6,538,371 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,534,512 - 6,538,374 (+)EnsemblGRCh38hg38GRCh38
GRCh37126,643,683 - 6,647,537 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,513,918 - 6,517,797 (+)NCBINCBI36Build 36hg18NCBI36
Build 34126,513,944 - 6,517,797NCBI
Celera128,260,518 - 8,264,397 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,497,829 - 6,501,781 (+)NCBIHuRef
CHM1_1126,642,592 - 6,646,544 (+)NCBICHM1_1
T2T-CHM13v2.0126,544,873 - 6,548,727 (+)NCBIT2T-CHM13v2.0
Gapdh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396125,138,812 - 125,143,450 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6125,138,678 - 125,143,430 (-)EnsemblGRCm39 Ensembl
GRCm386125,161,852 - 125,166,467 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6125,161,715 - 125,166,467 (-)EnsemblGRCm38mm10GRCm38
MGSCv376125,111,870 - 125,115,601 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366125,128,554 - 125,131,222 (-)NCBIMGSCv36mm8
Celera6126,831,711 - 126,835,442 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.32NCBI
Gapdh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,162,467 - 4,166,783 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,162,467 - 4,166,783 (+)NCBIChiLan1.0ChiLan1.0
GAPDH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,096,075 - 12,100,140 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,092,832 - 12,096,897 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0126,665,218 - 6,669,170 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,583,895 - 6,587,729 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,583,895 - 6,587,729 (+)Ensemblpanpan1.1panPan2
LOC100688969
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X51,925,654 - 51,926,724 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX42,758,798 - 42,759,848 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X52,892,500 - 52,893,549 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X50,867,280 - 50,868,330 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X52,198,694 - 52,199,710 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X52,119,573 - 52,120,589 (+)NCBIUU_Cfam_GSD_1.0
Gapdh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,575,598 - 102,580,238 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367091,243,147 - 1,247,903 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367091,243,149 - 1,247,782 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAPDH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl564,129,679 - 64,133,991 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1564,129,678 - 64,135,194 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,446,302 - 66,449,510 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5q12-q21NCBI
GAPDH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,569,029 - 6,572,877 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660631,653,527 - 1,657,405 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gapdh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,257,853 - 3,261,735 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,257,805 - 3,261,736 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Gapdh
17 total Variants

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:48
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000050443
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 38 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat

1 to 10 of 38 rows
PMC122612P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map18q12.1UniSTS
PMC128021P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map10q32.1UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map19p11UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map5q24UniSTS
Cytogenetic Map6q32UniSTS
PMC133764P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q22UniSTS
Cytogenetic Map9q13UniSTS
Cytogenetic Map16q11UniSTS
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map2q34UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map18q12.1UniSTS
PMC15575P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map10q32.1UniSTS
Cytogenetic Map19p11UniSTS
Cytogenetic Map2q42UniSTS
Cytogenetic Map11q22UniSTS
PMC164515P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q33UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map10q32.1UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map19p11UniSTS
Cytogenetic Map6q32UniSTS
PMC186377P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q33UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map8q22UniSTS
PMC26839P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16q11UniSTS
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map19p11UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map18q12.1UniSTS
PMC316856P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16q11UniSTS
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map10q32.1UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map18q12.1UniSTS
PMC327192P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q33UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map19p11UniSTS
PMC329392P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map19p11UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map2q42UniSTS
Cytogenetic Map10q32.1UniSTS
PMC128235P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q33UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map10q32.1UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map13q22UniSTS
Cytogenetic Map19p11UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map7q13UniSTS
Cytogenetic Map2q42UniSTS
Cytogenetic Map3q21UniSTS
RH140227  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,961,933 - 157,962,127 (+)MAPPERmRatBN7.2
Rnor_6.04157,675,972 - 157,676,165NCBIRnor6.0
Rnor_5.04224,693,156 - 224,693,349UniSTSRnor5.0
RGSC_v3.44161,281,791 - 161,281,984UniSTSRGSC3.4
Celera4146,698,964 - 146,699,157UniSTS
RH 3.4 Map41005.8UniSTS
Cytogenetic Map4q42UniSTS
PMC193571P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q33UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map10q32.1UniSTS
PMC104479P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0X55,897,275 - 55,897,778NCBIRnor5.0
Rnor_5.01207,898,087 - 207,898,589NCBIRnor5.0
Rnor_5.01208,042,287 - 208,042,789NCBIRnor5.0
RGSC_v3.4X93,852,831 - 93,853,333UniSTSRGSC3.4
RGSC_v3.41189,771,940 - 189,772,441UniSTSRGSC3.4
CeleraX72,115,994 - 72,116,496UniSTS
Celera1182,631,486 - 182,631,987UniSTS
Cytogenetic MapXq31UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map1q37UniSTS
PMC112827P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0X55,897,275 - 55,897,396NCBIRnor5.0
Rnor_5.01207,898,087 - 207,898,207NCBIRnor5.0
Rnor_5.01208,042,287 - 208,042,407NCBIRnor5.0
RGSC_v3.4X93,852,831 - 93,852,951UniSTSRGSC3.4
RGSC_v3.41189,771,940 - 189,772,059UniSTSRGSC3.4
CeleraX72,115,994 - 72,116,114UniSTS
Celera1182,631,486 - 182,631,605UniSTS
Cytogenetic MapXq31UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map1q37UniSTS
PMC115884P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0X55,897,276 - 55,897,582NCBIRnor5.0
Rnor_5.01207,898,088 - 207,898,393NCBIRnor5.0
Rnor_5.01208,042,288 - 208,042,593NCBIRnor5.0
RGSC_v3.4X93,852,832 - 93,853,137UniSTSRGSC3.4
RGSC_v3.41189,771,941 - 189,772,245UniSTSRGSC3.4
CeleraX72,115,995 - 72,116,300UniSTS
Celera1182,631,487 - 182,631,791UniSTS
Cytogenetic MapXq31UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map1q37UniSTS
PMC21468P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0X55,897,276 - 55,897,638NCBIRnor5.0
Rnor_5.01207,898,088 - 207,898,449NCBIRnor5.0
Rnor_5.01208,042,288 - 208,042,649NCBIRnor5.0
RGSC_v3.4X93,852,832 - 93,853,193UniSTSRGSC3.4
RGSC_v3.41189,771,941 - 189,772,301UniSTSRGSC3.4
CeleraX72,115,995 - 72,116,356UniSTS
Celera1182,631,487 - 182,631,847UniSTS
Cytogenetic MapXq31UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map1q37UniSTS
PMC266773P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01207,898,088 - 207,898,449NCBIRnor5.0
Rnor_5.0X55,897,276 - 55,897,638NCBIRnor5.0
Rnor_5.01208,042,288 - 208,042,649NCBIRnor5.0
RGSC_v3.41189,771,941 - 189,772,301UniSTSRGSC3.4
RGSC_v3.4X93,852,832 - 93,853,193UniSTSRGSC3.4
Celera1182,631,487 - 182,631,847UniSTS
CeleraX72,115,995 - 72,116,356UniSTS
Cytogenetic Map1q37UniSTS
Cytogenetic MapXq31UniSTS
Cytogenetic Map4q42UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 11 43 82 57 60 41 19 41 160 73 74 35 41 19


1 to 18 of 18 rows
RefSeq Transcripts NM_017008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB017801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC115415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ403053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M11561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M17701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M29341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U75401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 18 of 18 rows

Ensembl Acc Id: ENSRNOT00000050443   ⟹   ENSRNOP00000040878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,962,361 - 157,966,235 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110793   ⟹   ENSRNOP00000084281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,962,343 - 157,966,174 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114924   ⟹   ENSRNOP00000088495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,962,356 - 157,965,978 (-)Ensembl
RefSeq Acc Id: NM_017008   ⟹   NP_058704
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,648,592 - 159,652,467 (-)NCBI
mRatBN7.24157,962,358 - 157,966,233 (-)NCBI
Rnor_6.04157,676,396 - 157,680,271 (-)NCBI
Rnor_5.04224,693,580 - 224,697,455 (-)NCBI
RGSC_v3.44161,282,215 - 161,286,090 (-)RGD
Celera4146,699,388 - 146,703,263 (-)RGD
Sequence:
RefSeq Acc Id: XM_039107008   ⟹   XP_038962936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,648,592 - 159,653,436 (-)NCBI
mRatBN7.24157,962,312 - 157,967,158 (-)NCBI
RefSeq Acc Id: XM_063285517   ⟹   XP_063141587
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,648,592 - 159,652,464 (-)NCBI
RefSeq Acc Id: XM_063285518   ⟹   XP_063141588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,648,592 - 159,652,060 (-)NCBI
RefSeq Acc Id: XM_063285519   ⟹   XP_063141589
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,648,592 - 159,652,459 (-)NCBI
RefSeq Acc Id: NP_058704   ⟸   NM_017008
- UniProtKB: Q5M916 (UniProtKB/Swiss-Prot),   P09328 (UniProtKB/Swiss-Prot),   Q9QWU4 (UniProtKB/Swiss-Prot),   P04797 (UniProtKB/Swiss-Prot),   A6ILS6 (UniProtKB/TrEMBL),   A0A8L2QM97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038962936   ⟸   XM_039107008
- Peptide Label: isoform X1
- UniProtKB: Q5M916 (UniProtKB/Swiss-Prot),   P09328 (UniProtKB/Swiss-Prot),   P04797 (UniProtKB/Swiss-Prot),   Q9QWU4 (UniProtKB/Swiss-Prot),   A6ILS6 (UniProtKB/TrEMBL),   A0A8L2QM97 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000040878   ⟸   ENSRNOT00000050443
Ensembl Acc Id: ENSRNOP00000084281   ⟸   ENSRNOT00000110793
Ensembl Acc Id: ENSRNOP00000088495   ⟸   ENSRNOT00000114924
Name Modeler Protein Id AA Range Protein Structure
AF-P04797-F1-model_v2 AlphaFold P04797 1-333 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 46 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-43009 BioCyc
Ensembl Genes ENSRNOG00000018630 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000050443 ENTREZGENE
Gene3D-CATH Dihydrodipicolinate Reductase, domain 2 UniProtKB/Swiss-Prot
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6919611 IMAGE-MGC_LOAD
  IMAGE:7321006 IMAGE-MGC_LOAD
InterPro GlycerAld/Erythrose_P_DH UniProtKB/Swiss-Prot
  GlycerAld_3-P_DH_AS UniProtKB/Swiss-Prot
  GlycerAld_3-P_DH_cat UniProtKB/Swiss-Prot
  GlycerAld_3-P_DH_NAD(P)-bd UniProtKB/Swiss-Prot
  Glyceraldehyde-3-P_DH_1 UniProtKB/Swiss-Prot
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:24383 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105280 IMAGE-MGC_LOAD
  MGC:72650 IMAGE-MGC_LOAD
NCBI Gene 24383 ENTREZGENE
PANTHER GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE UniProtKB/Swiss-Prot
  PTHR10836 UniProtKB/Swiss-Prot
Pfam Gp_dh_C UniProtKB/Swiss-Prot
  Gp_dh_N UniProtKB/Swiss-Prot
PhenoGen Gapdh PhenoGen
PIRSF GAP_DH UniProtKB/Swiss-Prot
PRINTS G3PDHDRGNASE UniProtKB/Swiss-Prot
PROSITE GAPDH UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018630 RatGTEx
  ENSRNOG00000048704 RatGTEx
SMART Gp_dh_N UniProtKB/Swiss-Prot
Superfamily-SCOP Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain UniProtKB/Swiss-Prot
  SSF51735 UniProtKB/Swiss-Prot
UniProt A0A8I5ZXG9_RAT UniProtKB/TrEMBL
  A0A8I6AIZ9_RAT UniProtKB/TrEMBL
  A0A8L2QM97 ENTREZGENE, UniProtKB/TrEMBL
  A6ILS6 ENTREZGENE, UniProtKB/TrEMBL
  E9PTV9 ENTREZGENE, UniProtKB/TrEMBL
  G3P_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  P09328 ENTREZGENE
  P97617_RAT UniProtKB/TrEMBL
  Q0QEU1_RAT UniProtKB/TrEMBL
  Q5M916 ENTREZGENE
1 to 40 of 46 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-02-01 Gapdh    Gapd  glyceraldehyde-3-phosphate dehydrogenase  Symbol updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2002-06-10 Gapd  Glyceraldehyde-3-phosphate dehydrogenase      Symbol and Name status set to approved 70586 APPROVED

Note Type Note Reference
gene_expression expressed in atria and ventricles of the heart 625420
gene_expression expressed in all tissues 632774
gene_protein 333 amino acids 632774