(-)-anisomycin increases expression ISO CREBBP (Homo sapiens) 6480464 Anisomycin results in increased expression of CREBBP mRNA CTD PMID:24247028 (-)-epigallocatechin 3-gallate increases expression ISO CREBBP (Homo sapiens) 6480464 epigallocatechin gallate results in increased expression of CREBBP protein CTD PMID:31195006 (S)-nicotine increases expression ISO Crebbp (Mus musculus) 6480464 Nicotine results in increased expression of CREBBP mRNA CTD PMID:31945395 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases activity ISO CREBBP (Homo sapiens) 6480464 o and p'-DDT results in increased activity of CREBBP protein CTD PMID:22609851 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions ISO CREBBP (Homo sapiens) 6480464 o more ... CTD PMID:22609851 1,2-dimethylhydrazine decreases expression ISO Crebbp (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of CREBBP mRNA CTD PMID:22206623 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine decreases expression EXP 6480464 chlorcyclizine results in decreased expression of CREBBP mRNA CTD PMID:21058326 17beta-estradiol multiple interactions ISO CREBBP (Homo sapiens) 6480464 CREBBP mutant form inhibits the reaction [Estradiol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]] more ... CTD PMID:16417649 more ... 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of CREBBP mRNA CTD PMID:20068009 and PMID:32145629 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to CREBBP protein modified form] more ... CTD PMID:11981028 more ... 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one decreases expression ISO CREBBP (Homo sapiens) 6480464 Metribolone results in decreased expression of CREBBP mRNA and Metribolone results in decreased expression of CREBBP protein CTD PMID:15378487 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO CREBBP (Homo sapiens) 6480464 Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [CREBBP protein binds to KLK3 enhancer]] and Dihydrotestosterone promotes the reaction [CREBBP protein binds to KLK3 enhancer] CTD PMID:22258452 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:31826744 2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene increases activity ISO CREBBP (Homo sapiens) 6480464 2 more ... CTD PMID:22609851 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Crebbp (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of CREBBP mRNA CTD PMID:21570461 and PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of CREBBP mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CREBBP mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Crebbp (Mus musculus) 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CREBBP promoter] CTD PMID:19654925 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Crebbp (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of CREBBP mRNA CTD PMID:19465110 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO CREBBP (Homo sapiens) 6480464 Tetrachlorodibenzodioxin promotes the reaction [CREBBP protein binds to CYP1A1 promoter] CTD PMID:15964790 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of CREBBP mRNA CTD PMID:21346803 2-acetamidofluorene decreases expression EXP 6480464 2-Acetylaminofluorene results in decreased expression of CREBBP mRNA CTD PMID:22213190 2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid decreases activity ISO Crebbp (Mus musculus) 6480464 anacardic acid results in decreased activity of CREBBP protein CTD PMID:31927229 2-tert-butylhydroquinone multiple interactions ISO CREBBP (Homo sapiens) 6480464 1 more ... CTD PMID:21443188 3',5'-cyclic AMP multiple interactions ISO CREBBP (Homo sapiens) 6480464 CREBBP protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein] CTD PMID:20360387 3,4-methylenedioxymethamphetamine decreases expression ISO Crebbp (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of CREBBP mRNA CTD PMID:26251327 4,4'-sulfonyldiphenol multiple interactions ISO CREBBP (Homo sapiens) 6480464 [bisphenol S binds to and affects the folding of AR protein] affects the reaction [AR protein modified form binds to CREBBP protein modified form] and bisphenol S inhibits the reaction [ESR1 protein binds to CREBBP protein] CTD PMID:28751236 and PMID:29389661 4-hydroxynon-2-enal multiple interactions EXP 6480464 CREBBP protein inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of BDNF mRNA] CTD PMID:16337876 5-aza-2'-deoxycytidine decreases expression ISO Crebbp (Mus musculus) 6480464 Decitabine results in decreased expression of CREBBP mRNA CTD PMID:27915011 acetylsalicylic acid increases expression ISO CREBBP (Homo sapiens) 6480464 Aspirin results in increased expression of CREBBP mRNA CTD PMID:11906190 acrolein multiple interactions EXP 6480464 CREBBP protein inhibits the reaction [Acrolein results in decreased expression of BDNF mRNA] CTD PMID:16337876 aflatoxin B1 decreases methylation ISO CREBBP (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of CREBBP intron CTD PMID:30157460 aldosterone multiple interactions EXP 6480464 Aldosterone promotes the reaction [NR3C2 protein binds to CREBBP protein] and Aldosterone results in increased expression of and results in increased localization of CREBBP protein CTD PMID:19966502 all-trans-retinoic acid multiple interactions ISO CREBBP (Homo sapiens) 6480464 Tretinoin inhibits the reaction [[CREBBP protein binds to MAPK3 promoter] which affects the expression of MAPK3 mRNA] more ... CTD PMID:16050810 more ... all-trans-retinoic acid increases expression ISO CREBBP (Homo sapiens) 6480464 Tretinoin results in increased expression of CREBBP mRNA CTD PMID:28053092 all-trans-retinoic acid multiple interactions ISO Crebbp (Mus musculus) 6480464 Tretinoin inhibits the reaction [CREBBP protein binds to RETN promoter] CTD PMID:15047602 allethrin multiple interactions EXP 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of CREBBP mRNA and [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CREBBP mRNA CTD PMID:33051911 more ... ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CREBBP mRNA CTD PMID:16483693 Ammothamnine multiple interactions ISO Crebbp (Mus musculus) 6480464 oxymatrine inhibits the reaction [Carbon Tetrachloride results in increased expression of CREBBP mRNA] CTD PMID:18395914 androst-4-ene-3,17-dione increases activity ISO CREBBP (Homo sapiens) 6480464 Androstenedione results in increased activity of CREBBP protein CTD PMID:16467117 aripiprazole decreases expression EXP 6480464 Aripiprazole results in decreased expression of CREBBP mRNA CTD PMID:17868501 arsane affects methylation ISO CREBBP (Homo sapiens) 6480464 Arsenic affects the methylation of CREBBP gene CTD PMID:25304211 arsane increases expression ISO CREBBP (Homo sapiens) 6480464 Arsenic results in increased expression of CREBBP mRNA CTD PMID:28242323 arsenic atom affects methylation ISO CREBBP (Homo sapiens) 6480464 Arsenic affects the methylation of CREBBP gene CTD PMID:25304211 arsenic atom increases expression ISO CREBBP (Homo sapiens) 6480464 Arsenic results in increased expression of CREBBP mRNA CTD PMID:28242323 arsenite(3-) multiple interactions ISO CREBBP (Homo sapiens) 6480464 3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]] more ... CTD PMID:20199942 more ... arsenite(3-) increases acetylation ISO CREBBP (Homo sapiens) 6480464 arsenite results in increased acetylation of CREBBP protein CTD PMID:33097607 arsenous acid decreases expression ISO Crebbp (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of CREBBP mRNA CTD PMID:24831965 arsenous acid multiple interactions ISO CREBBP (Homo sapiens) 6480464 Arsenic Trioxide promotes the reaction [[CREBBP protein binds to CDKN1A promoter] which results in increased expression of CDKN1A mRNA] more ... CTD PMID:18822310 aurantio-obtusin increases phosphorylation ISO CREBBP (Homo sapiens) 6480464 aurantio-obtusin results in increased phosphorylation of CREBBP protein CTD PMID:35995123 azoxystrobin decreases expression ISO CREBBP (Homo sapiens) 6480464 azoxystrobin results in decreased expression of CREBBP mRNA CTD PMID:33512557 BAPTA multiple interactions ISO CREBBP (Homo sapiens) 6480464 1 more ... CTD PMID:21443188 benzo[a]pyrene multiple interactions ISO Crebbp (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to CREBBP promoter] CTD PMID:19654925 benzo[a]pyrene affects methylation ISO CREBBP (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of CREBBP intron and Benzo(a)pyrene affects the methylation of CREBBP promoter CTD PMID:27901495 and PMID:30157460 benzo[a]pyrene increases methylation ISO CREBBP (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of CREBBP 3' UTR CTD PMID:27901495 benzo[a]pyrene diol epoxide I decreases expression ISO CREBBP (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 berberine increases expression ISO CREBBP (Homo sapiens) 6480464 Berberine results in increased expression of CREBBP mRNA CTD PMID:27311644 bezafibrate multiple interactions ISO CREBBP (Homo sapiens) 6480464 Bezafibrate affects the reaction [PPARA protein binds to CREBBP protein] CTD PMID:19263263 bicalutamide multiple interactions ISO CREBBP (Homo sapiens) 6480464 bicalutamide inhibits the reaction [Metribolone results in decreased expression of CREBBP protein] CTD PMID:15378487 bisphenol A multiple interactions ISO CREBBP (Homo sapiens) 6480464 [bisphenol A binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to CREBBP protein modified form] more ... CTD PMID:24533973 more ... bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CREBBP mRNA CTD PMID:32145629 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CREBBP mRNA CTD PMID:30816183 and PMID:34947998 bisphenol A affects methylation ISO Crebbp (Mus musculus) 6480464 bisphenol A affects the methylation of CREBBP promoter CTD PMID:27334623 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CREBBP mRNA CTD PMID:25181051 bortezomib decreases expression ISO CREBBP (Homo sapiens) 6480464 Bortezomib results in decreased expression of CREBBP mRNA CTD PMID:25913414 bucladesine multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter] more ... CTD PMID:20685861 and PMID:36565944 bucladesine multiple interactions ISO Crebbp (Mus musculus) 6480464 [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter] and CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]] CTD PMID:19282384 butanal decreases expression ISO CREBBP (Homo sapiens) 6480464 butyraldehyde results in decreased expression of CREBBP mRNA CTD PMID:26079696 butyric acid increases expression ISO Crebbp (Mus musculus) 6480464 Butyric Acid results in increased expression of CREBBP mRNA CTD PMID:22687346 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of CREBBP mRNA CTD PMID:19167457 cadmium atom multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CREBBP mRNA CTD PMID:35301059 cadmium dichloride multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CREBBP mRNA CTD PMID:35301059 caffeine decreases phosphorylation ISO CREBBP (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of CREBBP protein CTD PMID:35688186 calcitriol affects localization ISO Crebbp (Mus musculus) 6480464 Calcitriol affects the localization of CREBBP protein CTD PMID:15647825 calcitriol multiple interactions ISO Crebbp (Mus musculus) 6480464 Calcitriol promotes the reaction [CREBBP protein binds to CYP24A1 promoter] and Calcitriol promotes the reaction [CREBBP protein binds to SPP1 promoter] CTD PMID:15647825 calyculin a increases phosphorylation ISO CREBBP (Homo sapiens) 6480464 calyculin A results in increased phosphorylation of CREBBP protein CTD PMID:22142222 camptothecin multiple interactions EXP 6480464 Camptothecin inhibits the reaction [RELA protein binds to CREBBP protein] more ... CTD PMID:13679428 carbon nanotube decreases expression ISO Crebbp (Mus musculus) 6480464 Nanotubes and Carbon results in decreased expression of CREBBP mRNA CTD PMID:25554681 cefaloridine decreases expression EXP 6480464 Cephaloridine results in decreased expression of CREBBP mRNA CTD PMID:18500788 chaetocin multiple interactions EXP 6480464 chaetocin inhibits the reaction [Dronabinol results in decreased expression of CREBBP mRNA] CTD PMID:29022873 and PMID:29481316 chloroprene decreases expression EXP 6480464 Chloroprene results in decreased expression of CREBBP mRNA CTD PMID:23125180 chlorpyrifos decreases expression ISO Crebbp (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of CREBBP mRNA CTD PMID:37019170 choline multiple interactions ISO Crebbp (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CREBBP gene CTD PMID:20938992 chromium atom multiple interactions ISO CREBBP (Homo sapiens) 6480464 Chromium affects the reaction [JUN protein binds to CREBBP protein] and Chromium inhibits the reaction [RELA protein binds to CREBBP protein] CTD PMID:10593907 chromium(6+) decreases expression EXP 6480464 chromium hexavalent ion results in decreased expression of CREBBP protein CTD PMID:32679048 ciglitazone multiple interactions ISO CREBBP (Homo sapiens) 6480464 ciglitazone inhibits the reaction [CREBBP protein binds to EGFR promoter] more ... CTD PMID:21080969 ciglitazone affects response to substance ISO CREBBP (Homo sapiens) 6480464 CREBBP affects the susceptibility to ciglitazone CTD PMID:21080969 cisplatin multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of CREBBP mRNA and [Cisplatin co-treated with Quercetin] results in increased expression of CREBBP mRNA CTD PMID:27392435 and PMID:27514524 cisplatin decreases expression ISO CREBBP (Homo sapiens) 6480464 Cisplatin results in decreased expression of CREBBP mRNA and Cisplatin results in decreased expression of CREBBP protein CTD PMID:17498666 and PMID:27594783 clobetasol decreases expression ISO Crebbp (Mus musculus) 6480464 Clobetasol results in decreased expression of CREBBP mRNA CTD PMID:27462272 clofibrate multiple interactions ISO CREBBP (Homo sapiens) 6480464 Clofibrate inhibits the reaction [CREBBP protein binds to EGFR promoter] more ... CTD PMID:21080969 clofibrate affects response to substance ISO CREBBP (Homo sapiens) 6480464 CREBBP affects the susceptibility to Clofibrate CTD PMID:21080969 cobalt dichloride multiple interactions ISO CREBBP (Homo sapiens) 6480464 [cobaltous chloride results in increased activity of SRC protein] promotes the reaction [[[HIF1A protein binds to STAT3 protein modified form] which binds to VEGFA promoter] binds to [APEX1 protein binds to CREBBP promoter]] CTD PMID:15735682 cocaine increases expression EXP 6480464 Cocaine results in increased expression of CREBBP mRNA CTD PMID:17898221 colforsin daropate hydrochloride multiple interactions ISO CREBBP (Homo sapiens) 6480464 Colforsin promotes the reaction [GCM1 protein binds to CREBBP protein] and CREBBP protein affects the reaction [Colforsin results in increased activity of GCM1 protein] CTD PMID:16166624 copper atom decreases expression EXP 6480464 Copper results in decreased expression of CREBBP mRNA CTD PMID:22465980 copper atom multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of CREBBP mRNA CTD PMID:30911355 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of CREBBP mRNA CTD PMID:22465980 copper(0) multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of CREBBP mRNA CTD PMID:30911355 copper(II) sulfate increases expression ISO CREBBP (Homo sapiens) 6480464 Copper Sulfate results in increased expression of CREBBP mRNA CTD PMID:19549813 corticosterone multiple interactions ISO Crebbp (Mus musculus) 6480464 2-(3 more ... CTD PMID:22850435 corticosterone decreases expression ISO Crebbp (Mus musculus) 6480464 Corticosterone results in decreased expression of CREBBP protein CTD PMID:22850435 curcumin multiple interactions ISO CREBBP (Homo sapiens) 6480464 Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [CREBBP protein binds to KLK3 enhancer]] CTD PMID:22258452 cyhalothrin multiple interactions EXP 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of CREBBP mRNA and [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CREBBP mRNA CTD PMID:33051911 more ... cypermethrin multiple interactions EXP 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of CREBBP mRNA and [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CREBBP mRNA CTD PMID:33051911 more ... cyproterone acetate multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to CREBBP protein modified form] more ... CTD PMID:15308689 and PMID:28751236 DDD increases activity ISO CREBBP (Homo sapiens) 6480464 Dichlorodiphenyldichloroethane results in increased activity of CREBBP protein CTD PMID:22609851 DDE increases activity ISO CREBBP (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased activity of CREBBP protein CTD PMID:22609851 and PMID:27589886 DDT increases activity ISO CREBBP (Homo sapiens) 6480464 DDT results in increased activity of CREBBP protein CTD PMID:22609851 deoxynivalenol increases expression ISO CREBBP (Homo sapiens) 6480464 deoxynivalenol results in increased expression of CREBBP mRNA CTD PMID:24247028 diarsenic trioxide decreases expression ISO Crebbp (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of CREBBP mRNA CTD PMID:24831965 diarsenic trioxide multiple interactions ISO CREBBP (Homo sapiens) 6480464 Arsenic Trioxide promotes the reaction [[CREBBP protein binds to CDKN1A promoter] which results in increased expression of CDKN1A mRNA] more ... CTD PMID:18822310 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of CREBBP mRNA CTD PMID:21266533 dicrotophos increases expression ISO CREBBP (Homo sapiens) 6480464 dicrotophos results in increased expression of CREBBP mRNA CTD PMID:28302478 diethylstilbestrol multiple interactions ISO CREBBP (Homo sapiens) 6480464 Diethylstilbestrol promotes the reaction [CREBBP protein binds to EZH2 promoter] more ... CTD PMID:24533973 more ... dinophysistoxin 1 increases expression ISO CREBBP (Homo sapiens) 6480464 dinophysistoxin 1 results in increased expression of CREBBP mRNA CTD PMID:28939011 dioxygen increases expression ISO Crebbp (Mus musculus) 6480464 Oxygen deficiency results in increased expression of CREBBP mRNA CTD PMID:22629407 dioxygen multiple interactions ISO Crebbp (Mus musculus) 6480464 Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of CREBBP mRNA] CTD PMID:22629407 diuron decreases expression EXP 6480464 Diuron results in decreased expression of CREBBP mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO CREBBP (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CREBBP mRNA CTD PMID:27188386 doxorubicin multiple interactions ISO CREBBP (Homo sapiens) 6480464 Doxorubicin promotes the reaction [CREBBP protein binds to ESR1 promoter] and Doxorubicin promotes the reaction [TP53 protein binds to CREBBP protein] CTD PMID:19351845 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of CREBBP mRNA CTD PMID:28865727 doxorubicin decreases expression ISO CREBBP (Homo sapiens) 6480464 Doxorubicin results in decreased expression of CREBBP protein CTD PMID:17498666 doxycycline multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter] and methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]] CTD PMID:36565944 elemental selenium decreases expression ISO CREBBP (Homo sapiens) 6480464 Selenium results in decreased expression of CREBBP mRNA CTD PMID:19244175 enzalutamide affects expression ISO CREBBP (Homo sapiens) 6480464 enzalutamide affects the expression of CREBBP mRNA CTD PMID:30940724 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of CREBBP mRNA CTD PMID:20655511 ethanol multiple interactions EXP 6480464 N-methyl-N-(6-methoxy-1-phenyl-1 more ... CTD PMID:20655511 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO CREBBP (Homo sapiens) 6480464 Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]] CTD PMID:21443188 fenthion increases expression ISO Crebbp (Mus musculus) 6480464 Fenthion results in increased expression of CREBBP mRNA CTD PMID:34813904 fenvalerate multiple interactions EXP 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of CREBBP mRNA and [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CREBBP mRNA CTD PMID:33051911 more ... folic acid multiple interactions ISO Crebbp (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CREBBP gene CTD PMID:20938992 folpet increases expression ISO Crebbp (Mus musculus) 6480464 folpet results in increased expression of CREBBP mRNA CTD PMID:31558096 formaldehyde decreases expression ISO CREBBP (Homo sapiens) 6480464 Formaldehyde results in decreased expression of CREBBP mRNA CTD PMID:20655997 FR900359 affects phosphorylation ISO CREBBP (Homo sapiens) 6480464 FR900359 affects the phosphorylation of CREBBP protein CTD PMID:37730182 fulvestrant multiple interactions ISO CREBBP (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of CREBBP gene more ... CTD PMID:18511507 more ... fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CREBBP protein]] CTD PMID:18511507 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of CREBBP mRNA CTD PMID:22061828 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of CREBBP mRNA CTD PMID:24349266 ibrutinib decreases response to substance ISO CREBBP (Homo sapiens) 6480464 CREBBP protein mutant form results in decreased susceptibility to ibrutinib CTD PMID:26254443 inulin multiple interactions ISO Crebbp (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CREBBP mRNA CTD PMID:36331819 irinotecan decreases expression ISO CREBBP (Homo sapiens) 6480464 Irinotecan analog results in decreased expression of CREBBP mRNA more ... CTD PMID:15956246 and PMID:18927307 KT 5823 multiple interactions ISO Crebbp (Mus musculus) 6480464 KT 5823 inhibits the reaction [2-(3 more ... CTD PMID:22850435 L-methionine multiple interactions ISO Crebbp (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CREBBP gene CTD PMID:20938992 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of CREBBP mRNA CTD PMID:24136188 linoleic acid multiple interactions ISO CREBBP (Homo sapiens) 6480464 Linoleic Acid affects the reaction [PPARA protein binds to CREBBP protein] CTD PMID:19263263 lipopolysaccharide multiple interactions ISO CREBBP (Homo sapiens) 6480464 Amino Acids more ... CTD PMID:22003094 lipopolysaccharide decreases expression ISO Crebbp (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of CREBBP mRNA CTD PMID:15919760 and PMID:16847310 medroxyprogesterone acetate multiple interactions ISO CREBBP (Homo sapiens) 6480464 Medroxyprogesterone Acetate promotes the reaction [CREBBP protein binds to SOD2 promoter] CTD PMID:20685861 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of CREBBP mRNA CTD PMID:30467583 methylmercury chloride affects expression EXP 6480464 methylmercuric chloride affects the expression of CREBBP mRNA CTD PMID:20864626 methylmercury chloride multiple interactions ISO CREBBP (Homo sapiens) 6480464 methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]] CTD PMID:36565944 mifepristone multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Mifepristone binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 enhancer] and [Mifepristone binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 promoter] CTD PMID:15308689 Mitotane increases activity ISO CREBBP (Homo sapiens) 6480464 Mitotane results in increased activity of CREBBP protein CTD PMID:22609851 monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of CREBBP mRNA CTD PMID:28954212 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO CREBBP (Homo sapiens) 6480464 N more ... CTD PMID:16579968 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Crebbp (Mus musculus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Sodium Oxybate results in increased phosphorylation of CREBBP protein] CTD PMID:16675135 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Crebbp (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Valproic Acid results in decreased expression of CREBBP protein] CTD PMID:27381264 niclosamide increases expression ISO CREBBP (Homo sapiens) 6480464 Niclosamide results in increased expression of CREBBP mRNA CTD PMID:22576131 nicotine increases expression ISO Crebbp (Mus musculus) 6480464 Nicotine results in increased expression of CREBBP mRNA CTD PMID:31945395 o-anisidine increases expression ISO CREBBP (Homo sapiens) 6480464 2-anisidine results in increased expression of CREBBP mRNA CTD PMID:28089782 okadaic acid increases phosphorylation ISO CREBBP (Homo sapiens) 6480464 Okadaic Acid results in increased phosphorylation of CREBBP protein CTD PMID:16059639 okadaic acid increases expression ISO CREBBP (Homo sapiens) 6480464 Okadaic Acid results in increased expression of CREBBP mRNA CTD PMID:28939011 oleic acid decreases expression EXP 6480464 Oleic Acid results in decreased expression of CREBBP mRNA CTD PMID:24349266 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of CREBBP mRNA CTD PMID:25729387 ozone multiple interactions ISO Crebbp (Mus musculus) 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of CREBBP mRNA CTD PMID:27106289 paracetamol affects expression ISO Crebbp (Mus musculus) 6480464 Acetaminophen affects the expression of CREBBP mRNA CTD PMID:17562736 paraquat increases expression EXP 6480464 Paraquat results in increased expression of CREBBP protein CTD PMID:20478973 paraquat decreases expression ISO CREBBP (Homo sapiens) 6480464 Paraquat results in decreased expression of CREBBP mRNA CTD PMID:28619522 perfluorooctane-1-sulfonic acid multiple interactions ISO Crebbp (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CREBBP mRNA CTD PMID:36331819 phenobarbital affects expression ISO CREBBP (Homo sapiens) 6480464 Phenobarbital affects the expression of CREBBP mRNA CTD PMID:19159669 phenobarbital decreases expression ISO Crebbp (Mus musculus) 6480464 Phenobarbital results in decreased expression of CREBBP mRNA CTD PMID:23091169 phenylephrine multiple interactions EXP 6480464 [Phenylephrine results in increased activity of CREBBP protein] which results in increased expression of NPPA protein more ... CTD PMID:11705990 more ... phenylephrine increases response to substance EXP 6480464 CREBBP protein results in increased susceptibility to Phenylephrine CTD PMID:12477714 phlorizin decreases expression ISO Crebbp (Mus musculus) 6480464 Phlorhizin results in decreased expression of CREBBP mRNA CTD PMID:22538082 phorbol 13-acetate 12-myristate multiple interactions ISO Crebbp (Mus musculus) 6480464 [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter] more ... CTD PMID:16474181 more ... pirinixic acid multiple interactions ISO CREBBP (Homo sapiens) 6480464 pirinixic acid affects the reaction [PPARA protein binds to CREBBP protein] CTD PMID:19263263 propanal decreases expression ISO CREBBP (Homo sapiens) 6480464 propionaldehyde results in decreased expression of CREBBP mRNA CTD PMID:26079696 propiconazole decreases expression ISO Crebbp (Mus musculus) 6480464 propiconazole results in decreased expression of CREBBP mRNA CTD PMID:21278054 pyrethrins decreases expression EXP 6480464 Pyrethrins results in decreased expression of CREBBP mRNA CTD PMID:34896426 quercetin multiple interactions ISO Crebbp (Mus musculus) 6480464 Quercetin inhibits the reaction [CREBBP protein binds to CXCL10 promoter] more ... CTD PMID:17449583 and PMID:21857970 quercetin affects activity EXP 6480464 Quercetin affects the activity of CREBBP modified form CTD PMID:19423323 quercetin increases expression ISO CREBBP (Homo sapiens) 6480464 Quercetin results in increased expression of CREBBP mRNA CTD PMID:14715546 quercetin decreases expression ISO CREBBP (Homo sapiens) 6480464 Quercetin results in decreased expression of CREBBP protein CTD PMID:15580028 quercetin multiple interactions ISO CREBBP (Homo sapiens) 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of CREBBP mRNA CTD PMID:27514524 raloxifene multiple interactions ISO CREBBP (Homo sapiens) 6480464 Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to IGF1 promoter] and Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to PTGS2 promoter] CTD PMID:17872375 resveratrol multiple interactions ISO CREBBP (Homo sapiens) 6480464 BCL2 protein inhibits the reaction [resveratrol promotes the reaction [PML protein binds to CREBBP protein]] more ... CTD PMID:19631782 and PMID:24771768 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [CREBBP protein results in increased acetylation of FOXO1 protein] CTD PMID:19740748 resveratrol multiple interactions ISO Crebbp (Mus musculus) 6480464 resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]] CTD PMID:16474181 resveratrol increases expression ISO CREBBP (Homo sapiens) 6480464 resveratrol results in increased expression of CREBBP mRNA CTD PMID:15149879 rotenone increases expression ISO Crebbp (Mus musculus) 6480464 Rotenone results in increased expression of CREBBP mRNA CTD PMID:21536665 rotenone decreases expression ISO CREBBP (Homo sapiens) 6480464 Rotenone results in decreased expression of CREBBP mRNA CTD PMID:33512557 SB 203580 multiple interactions ISO CREBBP (Homo sapiens) 6480464 SB 203580 inhibits the reaction [o and p'-DDT results in increased activity of CREBBP protein] CTD PMID:22609851 SB 431542 multiple interactions ISO CREBBP (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CREBBP mRNA CTD PMID:27188386 selenium atom decreases expression ISO CREBBP (Homo sapiens) 6480464 Selenium results in decreased expression of CREBBP mRNA CTD PMID:19244175 sodium arsenite increases expression ISO Crebbp (Mus musculus) 6480464 sodium arsenite results in increased expression of CREBBP mRNA CTD PMID:19822182 sodium arsenite multiple interactions ISO Crebbp (Mus musculus) 6480464 [DOT1L protein affects the susceptibility to sodium arsenite] which results in decreased expression of CREBBP mRNA CTD PMID:30130555 sodium arsenite decreases expression ISO CREBBP (Homo sapiens) 6480464 sodium arsenite results in decreased expression of CREBBP mRNA CTD PMID:12377979 sodium dodecyl sulfate increases expression ISO CREBBP (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in increased expression of CREBBP mRNA CTD PMID:31734321 sodium fluoride increases acetylation ISO Crebbp (Mus musculus) 6480464 Sodium Fluoride results in increased acetylation of CREBBP protein CTD PMID:31927229 sodium fluoride multiple interactions ISO Crebbp (Mus musculus) 6480464 Sodium Fluoride promotes the reaction [TRP53 protein binds to CREBBP protein] CTD PMID:31927229 Soman decreases expression EXP 6480464 Soman results in decreased expression of CREBBP mRNA CTD PMID:19281266 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of CREBBP mRNA CTD PMID:25905778 succimer multiple interactions ISO Crebbp (Mus musculus) 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of CREBBP mRNA CTD PMID:26378955 temozolomide increases expression ISO CREBBP (Homo sapiens) 6480464 Temozolomide results in increased expression of CREBBP mRNA CTD PMID:31758290 testosterone increases expression ISO CREBBP (Homo sapiens) 6480464 Testosterone results in increased expression of CREBBP mRNA CTD PMID:21880219 tetrachloromethane increases expression ISO Crebbp (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of CREBBP mRNA CTD PMID:18395914 tetrachloromethane multiple interactions ISO Crebbp (Mus musculus) 6480464 oxymatrine inhibits the reaction [Carbon Tetrachloride results in increased expression of CREBBP mRNA] CTD PMID:18395914 thapsigargin increases expression ISO CREBBP (Homo sapiens) 6480464 Thapsigargin results in increased expression of CREBBP mRNA CTD PMID:24247028 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of CREBBP mRNA CTD PMID:34492290 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of CREBBP mRNA CTD PMID:25729387 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of CREBBP mRNA CTD PMID:25729387 Tributyltin oxide increases expression ISO CREBBP (Homo sapiens) 6480464 bis(tri-n-butyltin)oxide results in increased expression of CREBBP mRNA CTD PMID:24247028 trichostatin A multiple interactions ISO CREBBP (Homo sapiens) 6480464 trichostatin A promotes the reaction [CREBBP protein binds to PDK4 promoter] CTD PMID:16757381 triptonide decreases expression ISO Crebbp (Mus musculus) 6480464 triptonide results in decreased expression of CREBBP mRNA CTD PMID:33045310 troglitazone multiple interactions ISO CREBBP (Homo sapiens) 6480464 RXRA protein inhibits the reaction [CREBBP protein results in increased susceptibility to troglitazone] CTD PMID:15581905 troglitazone decreases expression ISO Crebbp (Mus musculus) 6480464 troglitazone results in decreased expression of CREBBP mRNA CTD PMID:28973697 troglitazone increases response to substance EXP 6480464 CREBBP protein results in increased susceptibility to troglitazone CTD PMID:15581905 urethane increases expression ISO CREBBP (Homo sapiens) 6480464 Urethane results in increased expression of CREBBP mRNA CTD PMID:28818685 ursodeoxycholic acid decreases expression EXP 6480464 Ursodeoxycholic Acid results in decreased expression of CREBBP mRNA CTD PMID:19493473 valproic acid decreases expression ISO Crebbp (Mus musculus) 6480464 Valproic Acid results in decreased expression of CREBBP mRNA and Valproic Acid results in decreased expression of CREBBP protein CTD PMID:19136453 more ... valproic acid multiple interactions ISO Crebbp (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Valproic Acid results in decreased expression of CREBBP protein] CTD PMID:27381264 valproic acid multiple interactions ISO CREBBP (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CREBBP mRNA CTD PMID:27188386 valproic acid decreases expression ISO CREBBP (Homo sapiens) 6480464 Valproic Acid results in decreased expression of CREBBP mRNA CTD PMID:19101580 more ... valproic acid increases methylation ISO CREBBP (Homo sapiens) 6480464 Valproic Acid results in increased methylation of CREBBP gene CTD PMID:29154799 valproic acid affects expression ISO CREBBP (Homo sapiens) 6480464 Valproic Acid affects the expression of CREBBP mRNA CTD PMID:25979313 valproic acid decreases methylation ISO CREBBP (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of CREBBP gene CTD PMID:28853863 and PMID:29201983 vincristine increases expression ISO CREBBP (Homo sapiens) 6480464 Vincristine results in increased expression of CREBBP mRNA CTD PMID:23649840 vitamin E decreases expression ISO CREBBP (Homo sapiens) 6480464 Vitamin E results in decreased expression of CREBBP mRNA CTD PMID:19244175 vorinostat multiple interactions ISO CREBBP (Homo sapiens) 6480464 vorinostat promotes the reaction [PML protein binds to CREBBP protein] and vorinostat promotes the reaction [TP53 protein binds to PML protein binds to CREBBP protein] CTD PMID:19631782 zinc atom multiple interactions ISO Crebbp (Mus musculus) 6480464 Zinc promotes the reaction [MTF1 protein binds to EP300 protein binds to CREBBP protein] CTD PMID:18458062 zinc(0) multiple interactions ISO Crebbp (Mus musculus) 6480464 Zinc promotes the reaction [MTF1 protein binds to EP300 protein binds to CREBBP protein] CTD PMID:18458062