Symbol:
Pgd
Name:
phosphogluconate dehydrogenase
RGD ID:
1583832
Description:
Enables several functions, including NADP binding activity; carboxylic acid binding activity; and phosphogluconate dehydrogenase (decarboxylating) activity. Involved in D-gluconate metabolic process and pentose-phosphate shunt, oxidative branch. Predicted to be located in microtubule; neuron projection; and transport vesicle membrane. Predicted to be part of FANCM-MHF complex. Predicted to be active in cytosol. Orthologous to human PGD (phosphogluconate dehydrogenase); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - oxidative phase; ribose 5-phosphate isomerase deficiency pathway; INTERACTS WITH (R)-noradrenaline; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
6-phosphogluconate dehydrogenase, decarboxylating; 6-phosphogluconate dehydrogenase, decarboxylating-like; Cc2-27; LOC100360180; Pgd_mapped; phosphogluconate dehydrogenase (mapped)
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
PGD (phosphogluconate dehydrogenase) HGNC
HomoloGene, Inparanoid, NCBI, OrthoDB
Mus musculus (house mouse):
Pgd (phosphogluconate dehydrogenase) RGD
RGD
Chinchilla lanigera (long-tailed chinchilla):
Pgd (phosphogluconate dehydrogenase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
PGD (phosphogluconate dehydrogenase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Pgd (phosphogluconate dehydrogenase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
PGD (phosphogluconate dehydrogenase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
PGD (phosphogluconate dehydrogenase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Pgd (phosphogluconate dehydrogenase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Pgd (phosphogluconate dehydrogenase)
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
PGD (phosphogluconate dehydrogenase)
Alliance
DIOPT (HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
pgd (phosphogluconate dehydrogenase)
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
GND1
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
Pgd
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
T25B9.9
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
GND2
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
pgd
Alliance
DIOPT (OrthoFinder|PANTHER)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 5 164,865,830 - 164,882,029 (-) NCBI GRCr8 mRatBN7.2 5 159,582,746 - 159,598,945 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 5 159,561,271 - 159,742,778 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 5 162,299,447 - 162,315,646 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 5 164,120,366 - 164,136,488 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 5 164,076,736 - 164,092,858 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 5 165,966,128 - 165,982,327 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_5.0 5 169,614,705 - 169,630,921 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 5 166,221,292 - 166,237,485 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 5 157,853,711 - 157,869,910 (-) NCBI Celera Cytogenetic Map 5 q36 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Pgd Rat (1->4)-beta-D-glucan multiple interactions ISO Pgd (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PGD mRNA CTD PMID:36331819 Pgd Rat (E)-cinnamyl alcohol increases expression ISO PGD (Homo sapiens) 6480464 cinnamyl alcohol results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat (R)-noradrenaline increases activity EXP 6480464 Norepinephrine results in increased activity of PGD protein CTD PMID:1378361 Pgd Rat (R)-noradrenaline multiple interactions EXP 6480464 carvedilol inhibits the reaction [Norepinephrine results in increased activity of PGD mRNA] and carvedilol inhibits the reaction [Norepinephrine results in increased activity of PGD protein] CTD PMID:1378361 Pgd Rat (S)-naringenin decreases activity ISO PGD (Homo sapiens) 6480464 naringenin results in decreased activity of PGD protein CTD PMID:25130191 Pgd Rat 1,2-dimethylhydrazine increases expression ISO Pgd (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of PGD mRNA CTD PMID:22206623 Pgd Rat 1,2-dimethylhydrazine multiple interactions ISO Pgd (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PGD mRNA] CTD PMID:22206623 Pgd Rat 1,4-phenylenediamine increases expression ISO PGD (Homo sapiens) 6480464 4-phenylenediamine results in increased expression of PGD mRNA CTD PMID:16314067 Pgd Rat 1-chloro-2,4-dinitrobenzene increases expression ISO PGD (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat 1-chloro-2,4-dinitrobenzene affects binding ISO PGD (Homo sapiens) 6480464 Dinitrochlorobenzene binds to PGD protein CTD PMID:32991956 Pgd Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of PGD mRNA CTD PMID:30723492 Pgd Rat 17alpha-ethynylestradiol affects expression ISO Pgd (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of PGD mRNA CTD PMID:17555576 Pgd Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of PGD mRNA CTD PMID:17557909 Pgd Rat 17alpha-ethynylestradiol increases expression ISO Pgd (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of PGD mRNA CTD PMID:17942748 Pgd Rat 17alpha-ethynylestradiol multiple interactions ISO Pgd (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PGD mRNA CTD PMID:17942748 Pgd Rat 17beta-estradiol decreases expression ISO Pgd (Mus musculus) 6480464 Estradiol results in decreased expression of PGD mRNA CTD PMID:39298647 Pgd Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Pgd (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 Pgd Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Pgd (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17942748 more ... Pgd Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Pgd (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PGD mRNA CTD PMID:15034205 more ... Pgd Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Pgd (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PGD mRNA CTD PMID:21570461 Pgd Rat 2,6-dimethoxyphenol multiple interactions ISO PGD (Homo sapiens) 6480464 [pyrogallol 1 more ... CTD PMID:38598786 Pgd Rat 2-bromohexadecanoic acid multiple interactions ISO PGD (Homo sapiens) 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of PGD protein] CTD PMID:38195004 Pgd Rat 2-hydroxypropanoic acid increases expression ISO PGD (Homo sapiens) 6480464 Lactic Acid results in increased expression of PGD mRNA CTD PMID:20566472 and PMID:30851411 Pgd Rat 2-tert-butylhydroquinone increases expression ISO Pgd (Mus musculus) 6480464 2-tert-butylhydroquinone results in increased expression of PGD mRNA CTD PMID:16014739 Pgd Rat 3,4-methylenedioxymethamphetamine increases expression ISO Pgd (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PGD mRNA CTD PMID:20188158 Pgd Rat 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of PGD protein CTD PMID:34915118 Pgd Rat 4,4'-sulfonyldiphenol increases expression ISO PGD (Homo sapiens) 6480464 bisphenol S results in increased expression of PGD protein CTD PMID:34186270 Pgd Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases expression ISO PGD (Homo sapiens) 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PGD mRNA CTD PMID:19038236 Pgd Rat 4-hydroxynon-2-enal increases expression ISO Pgd (Mus musculus) 6480464 4-hydroxy-2-nonenal results in increased expression of PGD mRNA CTD PMID:19191707 Pgd Rat 4-hydroxyphenyl retinamide increases expression ISO PGD (Homo sapiens) 6480464 Fenretinide results in increased expression of PGD mRNA CTD PMID:16671099 Pgd Rat 5-methylphenazinium methyl sulfate increases activity ISO PGD (Homo sapiens) 6480464 Methylphenazonium Methosulfate results in increased activity of PGD protein CTD PMID:1901343 Pgd Rat 7,12-dimethyltetraphene multiple interactions ISO Pgd (Mus musculus) 6480464 [9 more ... CTD PMID:32553695 Pgd Rat acetamide decreases expression EXP 6480464 acetamide results in decreased expression of PGD mRNA CTD PMID:31881176 Pgd Rat aflatoxin B1 decreases expression ISO Pgd (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of PGD mRNA CTD PMID:19770486 Pgd Rat all-trans-retinoic acid multiple interactions ISO PGD (Homo sapiens) 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of PGD mRNA CTD PMID:15894607 Pgd Rat all-trans-retinoic acid increases expression ISO PGD (Homo sapiens) 6480464 Tretinoin results in increased expression of PGD mRNA CTD PMID:15498508 more ... Pgd Rat alpha-hexylcinnamaldehyde increases expression ISO PGD (Homo sapiens) 6480464 hexyl cinnamic aldehyde results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat amikacin decreases activity EXP 6480464 Amikacin results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat ampicillin decreases activity EXP 6480464 Ampicillin results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat aristolochic acid A increases expression ISO PGD (Homo sapiens) 6480464 aristolochic acid I results in increased expression of PGD protein CTD PMID:33212167 Pgd Rat Aroclor 1254 increases activity EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased activity of PGD protein CTD PMID:3099627 and PMID:4005852 Pgd Rat arsane multiple interactions ISO PGD (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PGD mRNA and [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PGD mRNA CTD PMID:32525701 and PMID:39836092 Pgd Rat arsenic atom multiple interactions ISO PGD (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PGD mRNA and [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PGD mRNA CTD PMID:32525701 and PMID:39836092 Pgd Rat arsenous acid decreases response to substance ISO PGD (Homo sapiens) 6480464 PGD protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 Pgd Rat arsenous acid multiple interactions ISO PGD (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PGD mRNA and Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PGD protein] CTD PMID:15894607 and PMID:26598702 Pgd Rat arsenous acid increases expression ISO PGD (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PGD mRNA CTD PMID:20458559 and PMID:25258189 Pgd Rat astaxanthin increases activity EXP 6480464 astaxanthine results in increased activity of PGD protein CTD PMID:28665548 and PMID:29975440 Pgd Rat Bandrowski's base increases expression ISO PGD (Homo sapiens) 6480464 Bandrowski's base results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat benzo[a]pyrene multiple interactions ISO Pgd (Mus musculus) 6480464 [Potassium Dichromate co-treated with potassium chromate(VI)] inhibits the reaction [Benzo(a)pyrene results in increased expression of PGD mRNA] CTD PMID:14625279 Pgd Rat benzo[a]pyrene decreases expression ISO Pgd (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of PGD mRNA CTD PMID:22228805 Pgd Rat benzo[a]pyrene increases expression ISO Pgd (Mus musculus) 6480464 Benzo(a)pyrene metabolite results in increased expression of PGD mRNA and Benzo(a)pyrene results in increased expression of PGD mRNA CTD PMID:14625279 more ... Pgd Rat benzoic acid increases expression ISO PGD (Homo sapiens) 6480464 Benzoic Acid results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat benzylpenicillin decreases activity EXP 6480464 Penicillin G results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat bis(2-ethylhexyl) phthalate multiple interactions ISO Pgd (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 Pgd Rat bis(2-ethylhexyl) phthalate decreases activity ISO Pgd (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased activity of PGD protein CTD PMID:31486570 Pgd Rat bisphenol A multiple interactions ISO Pgd (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 Pgd Rat bisphenol A decreases expression ISO PGD (Homo sapiens) 6480464 bisphenol A results in decreased expression of PGD protein CTD PMID:37567409 Pgd Rat bisphenol A multiple interactions ISO PGD (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of PGD gene CTD PMID:31601247 Pgd Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PGD mRNA CTD PMID:34947998 Pgd Rat bisphenol A increases expression ISO PGD (Homo sapiens) 6480464 bisphenol A results in increased expression of PGD mRNA and bisphenol A results in increased expression of PGD protein CTD PMID:29275510 and PMID:34186270 Pgd Rat bisphenol A affects expression ISO PGD (Homo sapiens) 6480464 bisphenol A affects the expression of PGD mRNA CTD PMID:30903817 Pgd Rat bisphenol AF increases expression ISO PGD (Homo sapiens) 6480464 bisphenol AF results in increased expression of PGD protein CTD PMID:34186270 Pgd Rat Bisphenol B increases expression ISO PGD (Homo sapiens) 6480464 bisphenol B results in increased expression of PGD protein CTD PMID:34186270 Pgd Rat bisphenol F increases expression ISO PGD (Homo sapiens) 6480464 bisphenol F results in increased expression of PGD protein CTD PMID:34186270 Pgd Rat bleomycin A5 decreases expression ISO PGD (Homo sapiens) 6480464 bleomycetin results in decreased expression of PGD mRNA CTD PMID:21040473 Pgd Rat buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of PGD mRNA CTD PMID:24136188 Pgd Rat cadmium atom decreases activity EXP 6480464 Cadmium results in decreased activity of PGD protein CTD PMID:29975440 Pgd Rat cadmium atom multiple interactions ISO PGD (Homo sapiens) 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of PGD protein] more ... CTD PMID:35301059 and PMID:38195004 Pgd Rat cadmium dichloride multiple interactions ISO PGD (Homo sapiens) 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of PGD protein] more ... CTD PMID:35301059 and PMID:38195004 Pgd Rat cadmium sulfate increases expression ISO Pgd (Mus musculus) 6480464 cadmium sulfate results in increased expression of PGD mRNA CTD PMID:16221973 Pgd Rat carbon nanotube decreases expression ISO Pgd (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25620056 Pgd Rat carbon nanotube increases expression ISO Pgd (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 Pgd Rat carvedilol multiple interactions EXP 6480464 carvedilol inhibits the reaction [Norepinephrine results in increased activity of PGD mRNA] and carvedilol inhibits the reaction [Norepinephrine results in increased activity of PGD protein] CTD PMID:1378361 Pgd Rat cefepime decreases activity EXP 6480464 cefepime results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat cefotaxime decreases activity EXP 6480464 Cefotaxime results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat chloramphenicol decreases activity EXP 6480464 Chloramphenicol results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat chloroprene increases expression ISO Pgd (Mus musculus) 6480464 Chloroprene results in increased expression of PGD mRNA CTD PMID:23125180 Pgd Rat choline multiple interactions ISO Pgd (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of PGD more ... CTD PMID:20938992 Pgd Rat chrysin decreases activity ISO PGD (Homo sapiens) 6480464 chrysin results in decreased activity of PGD protein CTD PMID:25130191 Pgd Rat cinnamyl alcohol increases expression ISO PGD (Homo sapiens) 6480464 cinnamyl alcohol results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat ciprofloxacin decreases activity EXP 6480464 Ciprofloxacin results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat cis-caffeic acid decreases activity ISO PGD (Homo sapiens) 6480464 caffeic acid results in decreased activity of PGD protein CTD PMID:25130191 Pgd Rat cisplatin multiple interactions ISO PGD (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of PGD mRNA CTD PMID:27392435 Pgd Rat clobetasol increases expression ISO Pgd (Mus musculus) 6480464 Clobetasol results in increased expression of PGD mRNA CTD PMID:27462272 Pgd Rat clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of PGD protein CTD PMID:8240402 Pgd Rat cobalt dichloride decreases expression ISO PGD (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of PGD mRNA CTD PMID:19376846 Pgd Rat copper(II) chloride increases expression ISO PGD (Homo sapiens) 6480464 cupric chloride results in increased expression of PGD mRNA CTD PMID:38568856 Pgd Rat curcumin increases expression EXP 6480464 Curcumin results in increased expression of PGD mRNA CTD PMID:18299980 Pgd Rat cyclosporin A increases expression ISO PGD (Homo sapiens) 6480464 Cyclosporine results in increased expression of PGD mRNA CTD PMID:20106945 Pgd Rat diarsenic trioxide decreases response to substance ISO PGD (Homo sapiens) 6480464 PGD protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 Pgd Rat diarsenic trioxide increases expression ISO PGD (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PGD mRNA CTD PMID:20458559 and PMID:25258189 Pgd Rat diarsenic trioxide multiple interactions ISO PGD (Homo sapiens) 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PGD mRNA and Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to PGD protein] CTD PMID:15894607 and PMID:26598702 Pgd Rat Dibutyl phosphate affects expression ISO PGD (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of PGD mRNA CTD PMID:37042841 Pgd Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of PGD mRNA CTD PMID:21266533 Pgd Rat diethyl maleate increases activity EXP 6480464 diethyl maleate results in increased activity of PGD protein CTD PMID:3099627 Pgd Rat digoxin decreases activity EXP 6480464 Digoxin results in decreased activity of PGD protein CTD PMID:26820767 Pgd Rat dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression ISO PGD (Homo sapiens) 6480464 Antimony Potassium Tartrate results in increased expression of PGD protein CTD PMID:28713220 Pgd Rat diquat increases expression ISO Pgd (Mus musculus) 6480464 Diquat results in increased expression of PGD mRNA CTD PMID:16962985 and PMID:36851058 Pgd Rat disulfiram increases expression ISO PGD (Homo sapiens) 6480464 Disulfiram results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat dopamine decreases activity EXP 6480464 Dopamine results in decreased activity of PGD protein CTD PMID:26820767 Pgd Rat ellagic acid decreases activity ISO PGD (Homo sapiens) 6480464 Ellagic Acid results in decreased activity of PGD protein CTD PMID:25130191 Pgd Rat eugenol increases expression ISO PGD (Homo sapiens) 6480464 Eugenol results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat ferulic acid decreases activity ISO PGD (Homo sapiens) 6480464 ferulic acid results in decreased activity of PGD protein CTD PMID:25130191 Pgd Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of PGD mRNA CTD PMID:24136188 Pgd Rat folic acid multiple interactions ISO Pgd (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of PGD more ... CTD PMID:20938992 and PMID:22206623 Pgd Rat fulvestrant multiple interactions ISO PGD (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of PGD gene CTD PMID:31601247 Pgd Rat furfural multiple interactions ISO PGD (Homo sapiens) 6480464 [pyrogallol 1 more ... CTD PMID:38598786 Pgd Rat furosemide decreases activity EXP 6480464 Furosemide results in decreased activity of PGD protein CTD PMID:26820767 Pgd Rat gamma-hexachlorocyclohexane affects activity EXP 6480464 Hexachlorocyclohexane affects the activity of PGD protein CTD PMID:7535533 Pgd Rat gentamycin decreases activity EXP 6480464 Gentamicins results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat hexane increases expression ISO PGD (Homo sapiens) 6480464 n-hexane results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat iron trichloride affects expression EXP 6480464 ferric chloride affects the expression of PGD mRNA CTD PMID:24599681 Pgd Rat iron trichloride decreases expression EXP 6480464 ferric chloride results in decreased expression of PGD mRNA CTD PMID:30506659 Pgd Rat iron trichloride increases expression EXP 6480464 ferric chloride results in increased expression of PGD protein CTD PMID:30506659 Pgd Rat iron trichloride decreases activity EXP 6480464 ferric chloride results in decreased activity of PGD protein CTD PMID:24599681 Pgd Rat isepamicin decreases activity EXP 6480464 isepamicin results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat isoeugenol increases expression ISO PGD (Homo sapiens) 6480464 isoeugenol results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat isoflavones increases expression ISO PGD (Homo sapiens) 6480464 Isoflavones results in increased expression of PGD mRNA CTD PMID:17374662 Pgd Rat isotretinoin decreases expression ISO PGD (Homo sapiens) 6480464 Isotretinoin results in decreased expression of PGD mRNA CTD PMID:20436886 Pgd Rat ivermectin decreases expression ISO PGD (Homo sapiens) 6480464 Ivermectin results in decreased expression of PGD protein CTD PMID:32959892 Pgd Rat L-methionine multiple interactions ISO Pgd (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of PGD more ... CTD PMID:20938992 Pgd Rat lead diacetate decreases activity EXP 6480464 lead acetate results in decreased activity of PGD protein CTD PMID:25228019 Pgd Rat lead diacetate increases expression ISO PGD (Homo sapiens) 6480464 lead acetate results in increased expression of PGD mRNA CTD PMID:38568856 Pgd Rat lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of PGD mRNA CTD PMID:22641619 Pgd Rat lead(0) affects expression ISO PGD (Homo sapiens) 6480464 Lead affects the expression of PGD mRNA CTD PMID:28903495 Pgd Rat leflunomide increases expression EXP 6480464 leflunomide results in increased expression of PGD mRNA CTD PMID:24136188 Pgd Rat manganese atom multiple interactions ISO PGD (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PGD mRNA CTD PMID:39836092 Pgd Rat manganese(0) multiple interactions ISO PGD (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PGD mRNA CTD PMID:39836092 Pgd Rat manganese(II) chloride multiple interactions ISO PGD (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PGD mRNA CTD PMID:39836092 Pgd Rat menadione increases expression ISO Pgd (Mus musculus) 6480464 Vitamin K 3 results in increased expression of PGD mRNA CTD PMID:25270620 Pgd Rat methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of PGD gene CTD PMID:35440735 Pgd Rat methyl salicylate increases expression ISO PGD (Homo sapiens) 6480464 methyl salicylate results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat methylene blue increases activity ISO PGD (Homo sapiens) 6480464 Methylene Blue results in increased activity of PGD protein CTD PMID:1901343 Pgd Rat methylmercury chloride increases expression ISO PGD (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of PGD mRNA CTD PMID:23179753 Pgd Rat microcystin-LR increases expression ISO Pgd (Mus musculus) 6480464 cyanoginosin LR results in increased expression of PGD mRNA CTD PMID:17654400 Pgd Rat N-acetyl-L-cysteine increases activity EXP 6480464 Acetylcysteine results in increased activity of PGD protein CTD PMID:3099627 Pgd Rat N-methylformamide affects expression ISO Pgd (Mus musculus) 6480464 methylformamide affects the expression of PGD mRNA and methylformamide analog affects the expression of PGD mRNA CTD PMID:17040096 Pgd Rat N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of PGD mRNA CTD PMID:19638242 Pgd Rat NADP zwitterion increases expression EXP 6480464 NADP results in increased expression of PGD protein CTD PMID:1922005 Pgd Rat NADP(+) increases expression EXP 6480464 NADP results in increased expression of PGD protein CTD PMID:1922005 Pgd Rat netilmycin decreases activity EXP 6480464 Netilmicin results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat nickel sulfate increases expression ISO PGD (Homo sapiens) 6480464 nickel sulfate results in increased expression of PGD mRNA CTD PMID:16314067 and PMID:20566472 Pgd Rat ofloxacin decreases activity EXP 6480464 Ofloxacin results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat paracetamol affects expression ISO Pgd (Mus musculus) 6480464 Acetaminophen affects the expression of PGD mRNA CTD PMID:17562736 Pgd Rat paracetamol increases expression ISO Pgd (Mus musculus) 6480464 Acetaminophen results in increased expression of PGD mRNA CTD PMID:29246445 Pgd Rat paracetamol multiple interactions ISO Pgd (Mus musculus) 6480464 PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of PGD mRNA] CTD PMID:29246445 Pgd Rat paracetamol increases expression ISO PGD (Homo sapiens) 6480464 Acetaminophen results in increased expression of PGD mRNA CTD PMID:21420995 Pgd Rat paraquat affects expression ISO Pgd (Mus musculus) 6480464 Paraquat affects the expression of PGD mRNA CTD PMID:27788593 Pgd Rat paraquat increases expression ISO PGD (Homo sapiens) 6480464 Paraquat results in increased expression of PGD protein CTD PMID:34064677 Pgd Rat paraquat increases expression EXP 6480464 Paraquat results in increased expression of PGD mRNA CTD PMID:32680482 Pgd Rat pentachlorophenol increases expression ISO Pgd (Mus musculus) 6480464 Pentachlorophenol results in increased expression of PGD mRNA CTD PMID:23892564 Pgd Rat perfluorooctane-1-sulfonic acid increases expression ISO PGD (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in increased expression of PGD mRNA CTD PMID:27153767 Pgd Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Pgd (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PGD mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of PGD mRNA CTD PMID:36331819 Pgd Rat phenobarbital multiple interactions ISO Pgd (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of PGD mRNA] CTD PMID:19482888 Pgd Rat phenobarbital increases expression ISO Pgd (Mus musculus) 6480464 Phenobarbital results in increased expression of PGD mRNA CTD PMID:19482888 Pgd Rat phenobarbital affects expression ISO Pgd (Mus musculus) 6480464 Phenobarbital affects the expression of PGD mRNA CTD PMID:23091169 Pgd Rat phosgene affects expression ISO Pgd (Mus musculus) 6480464 Phosgene affects the expression of PGD mRNA CTD PMID:16300373 Pgd Rat pirinixic acid increases expression ISO Pgd (Mus musculus) 6480464 pirinixic acid results in increased expression of PGD mRNA CTD PMID:18301758 more ... Pgd Rat potassium chromate multiple interactions ISO Pgd (Mus musculus) 6480464 [Potassium Dichromate co-treated with potassium chromate(VI)] inhibits the reaction [Benzo(a)pyrene results in increased expression of PGD mRNA] CTD PMID:14625279 Pgd Rat potassium dichromate multiple interactions ISO Pgd (Mus musculus) 6480464 [Potassium Dichromate co-treated with potassium chromate(VI)] inhibits the reaction [Benzo(a)pyrene results in increased expression of PGD mRNA] CTD PMID:14625279 Pgd Rat propan-2-ol increases expression ISO PGD (Homo sapiens) 6480464 2-Propanol results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat propiconazole increases expression ISO Pgd (Mus musculus) 6480464 propiconazole results in increased expression of PGD mRNA CTD PMID:19363144 Pgd Rat pyrroles increases activity ISO PGD (Homo sapiens) 6480464 Pyrroles results in increased activity of PGD protein CTD PMID:1901343 Pgd Rat quercetin increases expression ISO PGD (Homo sapiens) 6480464 Quercetin results in increased expression of PGD mRNA CTD PMID:21632981 Pgd Rat rac-lactic acid increases expression ISO PGD (Homo sapiens) 6480464 Lactic Acid results in increased expression of PGD mRNA CTD PMID:20566472 and PMID:30851411 Pgd Rat resveratrol multiple interactions ISO PGD (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of PGD mRNA CTD PMID:23557933 Pgd Rat SB 431542 multiple interactions ISO PGD (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of PGD protein CTD PMID:37664457 Pgd Rat silicon dioxide affects secretion ISO PGD (Homo sapiens) 6480464 Silicon Dioxide analog affects the secretion of PGD protein CTD PMID:25895662 Pgd Rat silicon dioxide decreases expression ISO PGD (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of PGD mRNA CTD PMID:25895662 Pgd Rat silver atom increases expression ISO Pgd (Mus musculus) 6480464 Silver results in increased expression of PGD mRNA CTD PMID:27131904 Pgd Rat silver(0) increases expression ISO Pgd (Mus musculus) 6480464 Silver results in increased expression of PGD mRNA CTD PMID:27131904 Pgd Rat sinapic acid decreases activity ISO PGD (Homo sapiens) 6480464 sinapinic acid results in decreased activity of PGD protein CTD PMID:25130191 Pgd Rat sodium arsenate multiple interactions ISO PGD (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PGD mRNA CTD PMID:32525701 Pgd Rat sodium arsenite increases expression ISO PGD (Homo sapiens) 6480464 sodium arsenite results in increased expression of PGD mRNA CTD PMID:20886546 more ... Pgd Rat sodium arsenite multiple interactions ISO PGD (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PGD mRNA CTD PMID:39836092 Pgd Rat sodium chloride multiple interactions ISO PGD (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of PGD protein more ... CTD PMID:38598786 Pgd Rat sodium dodecyl sulfate increases expression ISO PGD (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat sulforaphane increases expression ISO PGD (Homo sapiens) 6480464 sulforaphane results in increased expression of PGD mRNA CTD PMID:26833863 and PMID:31838189 Pgd Rat tamibarotene increases expression ISO PGD (Homo sapiens) 6480464 tamibarotene results in increased expression of PGD mRNA CTD PMID:15498508 Pgd Rat tamoxifen affects expression ISO Pgd (Mus musculus) 6480464 Tamoxifen affects the expression of PGD mRNA CTD PMID:17555576 Pgd Rat teicoplanin decreases activity EXP 6480464 Teicoplanin results in decreased activity of PGD protein CTD PMID:15558954 Pgd Rat temozolomide decreases expression ISO PGD (Homo sapiens) 6480464 Temozolomide results in decreased expression of PGD mRNA CTD PMID:31758290 Pgd Rat tetrachloromethane affects expression ISO Pgd (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of PGD mRNA CTD PMID:17484886 Pgd Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of PGD mRNA CTD PMID:31150632 Pgd Rat tetrachloromethane increases expression ISO Pgd (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of PGD mRNA CTD PMID:27339419 and PMID:31919559 Pgd Rat thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of PGD protein CTD PMID:35544339 Pgd Rat titanium dioxide decreases methylation ISO Pgd (Mus musculus) 6480464 titanium dioxide results in decreased methylation of PGD gene CTD PMID:35295148 Pgd Rat trans-caffeic acid decreases activity ISO PGD (Homo sapiens) 6480464 caffeic acid results in decreased activity of PGD protein CTD PMID:25130191 Pgd Rat trans-isoeugenol increases expression ISO PGD (Homo sapiens) 6480464 isoeugenol results in increased expression of PGD mRNA CTD PMID:20566472 Pgd Rat trimellitic anhydride increases expression ISO Pgd (Mus musculus) 6480464 trimellitic anhydride results in increased expression of PGD mRNA CTD PMID:19042947 Pgd Rat triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of PGD mRNA CTD PMID:30589522 Pgd Rat triphenyl phosphate affects expression ISO PGD (Homo sapiens) 6480464 triphenyl phosphate affects the expression of PGD mRNA CTD PMID:37042841 Pgd Rat uranium atom affects expression ISO PGD (Homo sapiens) 6480464 Uranium affects the expression of PGD mRNA CTD PMID:15672453 Pgd Rat urethane increases expression ISO PGD (Homo sapiens) 6480464 Urethane results in increased expression of PGD mRNA CTD PMID:28818685 Pgd Rat valproic acid increases methylation ISO PGD (Homo sapiens) 6480464 Valproic Acid results in increased methylation of PGD gene CTD PMID:29154799 Pgd Rat vancomycin decreases expression ISO Pgd (Mus musculus) 6480464 Vancomycin results in decreased expression of PGD mRNA CTD PMID:18930951 Pgd Rat zearalenone decreases expression ISO Pgd (Mus musculus) 6480464 Zearalenone results in decreased expression of PGD protein CTD PMID:25058043 Pgd Rat zinc atom decreases expression ISO PGD (Homo sapiens) 6480464 Zinc results in decreased expression of PGD mRNA CTD PMID:18316168 Pgd Rat zinc(0) decreases expression ISO PGD (Homo sapiens) 6480464 Zinc results in decreased expression of PGD mRNA CTD PMID:18316168
Imported Annotations - SMPDB
(1->4)-beta-D-glucan (ISO) (E)-cinnamyl alcohol (ISO) (R)-noradrenaline (EXP) (S)-naringenin (ISO) 1,2-dimethylhydrazine (ISO) 1,4-phenylenediamine (ISO) 1-chloro-2,4-dinitrobenzene (ISO) 1-naphthyl isothiocyanate (EXP) 17alpha-ethynylestradiol (EXP,ISO) 17beta-estradiol (ISO) 2,2',4,4',5,5'-hexachlorobiphenyl (ISO) 2,3,7,8-tetrachlorodibenzodioxine (ISO) 2,6-dimethoxyphenol (ISO) 2-bromohexadecanoic acid (ISO) 2-hydroxypropanoic acid (ISO) 2-tert-butylhydroquinone (ISO) 3,4-methylenedioxymethamphetamine (ISO) 3-chloropropane-1,2-diol (EXP) 4,4'-sulfonyldiphenol (ISO) 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (ISO) 4-hydroxynon-2-enal (ISO) 4-hydroxyphenyl retinamide (ISO) 5-methylphenazinium methyl sulfate (ISO) 7,12-dimethyltetraphene (ISO) acetamide (EXP) aflatoxin B1 (ISO) all-trans-retinoic acid (ISO) alpha-hexylcinnamaldehyde (ISO) amikacin (EXP) ampicillin (EXP) aristolochic acid A (ISO) Aroclor 1254 (EXP) arsane (ISO) arsenic atom (ISO) arsenous acid (ISO) astaxanthin (EXP) Bandrowski's base (ISO) benzo[a]pyrene (ISO) benzoic acid (ISO) benzylpenicillin (EXP) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol AF (ISO) Bisphenol B (ISO) bisphenol F (ISO) bleomycin A5 (ISO) buspirone (EXP) cadmium atom (EXP,ISO) cadmium dichloride (ISO) cadmium sulfate (ISO) carbon nanotube (ISO) carvedilol (EXP) cefepime (EXP) cefotaxime (EXP) chloramphenicol (EXP) chloroprene (ISO) choline (ISO) chrysin (ISO) cinnamyl alcohol (ISO) ciprofloxacin (EXP) cis-caffeic acid (ISO) cisplatin (ISO) clobetasol (ISO) clofibrate (EXP) cobalt dichloride (ISO) copper(II) chloride (ISO) curcumin (EXP) cyclosporin A (ISO) diarsenic trioxide (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (EXP) diethyl maleate (EXP) digoxin (EXP) dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate (ISO) diquat (ISO) disulfiram (ISO) dopamine (EXP) ellagic acid (ISO) eugenol (ISO) ferulic acid (ISO) flutamide (EXP) folic acid (ISO) fulvestrant (ISO) furfural (ISO) furosemide (EXP) gamma-hexachlorocyclohexane (EXP) gentamycin (EXP) hexane (ISO) iron trichloride (EXP) isepamicin (EXP) isoeugenol (ISO) isoflavones (ISO) isotretinoin (ISO) ivermectin (ISO) L-methionine (ISO) lead diacetate (EXP,ISO) lead(0) (ISO) leflunomide (EXP) manganese atom (ISO) manganese(0) (ISO) manganese(II) chloride (ISO) menadione (ISO) methoxychlor (EXP) methyl salicylate (ISO) methylene blue (ISO) methylmercury chloride (ISO) microcystin-LR (ISO) N-acetyl-L-cysteine (EXP) N-methylformamide (ISO) N-nitrosodiethylamine (EXP) NADP zwitterion (EXP) NADP(+) (EXP) netilmycin (EXP) nickel sulfate (ISO) ofloxacin (EXP) paracetamol (ISO) paraquat (EXP,ISO) pentachlorophenol (ISO) perfluorooctane-1-sulfonic acid (ISO) phenobarbital (ISO) phosgene (ISO) pirinixic acid (ISO) potassium chromate (ISO) potassium dichromate (ISO) propan-2-ol (ISO) propiconazole (ISO) pyrroles (ISO) quercetin (ISO) rac-lactic acid (ISO) resveratrol (ISO) SB 431542 (ISO) silicon dioxide (ISO) silver atom (ISO) silver(0) (ISO) sinapic acid (ISO) sodium arsenate (ISO) sodium arsenite (ISO) sodium chloride (ISO) sodium dodecyl sulfate (ISO) sulforaphane (ISO) tamibarotene (ISO) tamoxifen (ISO) teicoplanin (EXP) temozolomide (ISO) tetrachloromethane (EXP,ISO) thapsigargin (EXP) titanium dioxide (ISO) trans-caffeic acid (ISO) trans-isoeugenol (ISO) trimellitic anhydride (ISO) triphenyl phosphate (EXP,ISO) uranium atom (ISO) urethane (ISO) valproic acid (ISO) vancomycin (ISO) zearalenone (ISO) zinc atom (ISO) zinc(0) (ISO)
1.
Purification of rat kidney glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase enzymes using 2',5'-ADP Sepharose 4B affinity in a single chromatography step.
Adem S and Ciftci M, Protein Expr Purif. 2012 Jan;81(1):1-4. doi: 10.1016/j.pep.2011.08.031. Epub 2011 Sep 10.
2.
The cellular fate of glucose and its relevance in type 2 diabetes.
Bouche C, etal., Endocr Rev. 2004 Oct;25(5):807-30.
3.
The pentose phosphate pathway in the endoplasmic reticulum.
Bublitz C and Steavenson S, J Biol Chem. 1988 Sep 15;263(26):12849-53.
4.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.
Hexose-6-phosphate and 6-phosphogluconate dehydrogenases of rat liver microsomes. Involvement in NADPH and carbon dioxide generation in the luminal space of microsomal vesicles.
Hino Y and Minakami S, J Biochem (Tokyo). 1982 Aug;92(2):547-57.
6.
SMPDB Annotation Import Pipeline
Pipeline to import SMPDB annotations from SMPDB into RGD
7.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
8.
Effect of Anabolic Steroid Nandrolone Decanoate on the Properties of Certain Enzymes in the Heart, Liver, and Muscle of Rats, and their Effect on Rats' Cardiac Electrophysiology.
Tylicki A, etal., Horm Metab Res. 2007 Apr;39(4):268-72.
9.
Significance of the 5-phosphoribosyl-1-pyrophosphate pool for cardiac purine and pyrimidine nucleotide synthesis: studies with ribose, adenine, inosine, and orotic acid in rats.
Zimmer HG Cardiovasc Drugs Ther. 1998 Sep;12 Suppl 2:179-87.
Pgd Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 5 164,865,830 - 164,882,029 (-) NCBI GRCr8 mRatBN7.2 5 159,582,746 - 159,598,945 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 5 159,561,271 - 159,742,778 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 5 162,299,447 - 162,315,646 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 5 164,120,366 - 164,136,488 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 5 164,076,736 - 164,092,858 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 5 165,966,128 - 165,982,327 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_5.0 5 169,614,705 - 169,630,921 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 5 166,221,292 - 166,237,485 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 5 157,853,711 - 157,869,910 (-) NCBI Celera Cytogenetic Map 5 q36 NCBI
PGD Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 1 10,399,064 - 10,420,511 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 1 10,398,592 - 10,420,511 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 1 10,459,121 - 10,480,568 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 1 10,381,672 - 10,402,788 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 1 10,393,350 - 10,414,467 NCBI Celera 1 9,570,477 - 9,591,593 (+) NCBI Celera Cytogenetic Map 1 p36.22 NCBI HuRef 1 9,612,776 - 9,633,839 (+) NCBI HuRef CHM1_1 1 10,447,954 - 10,469,073 (+) NCBI CHM1_1 T2T-CHM13v2.0 1 9,942,673 - 9,964,125 (+) NCBI T2T-CHM13v2.0
Pgd Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 4 149,234,448 - 149,251,162 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 4 149,234,448 - 149,251,228 (-) Ensembl GRCm39 Ensembl GRCm38 4 149,149,991 - 149,166,705 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 4 149,149,991 - 149,166,771 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 4 148,524,094 - 148,540,816 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 4 147,993,785 - 148,010,507 (-) NCBI MGSCv36 mm8 Celera 4 151,416,090 - 151,432,815 (-) NCBI Celera Cytogenetic Map 4 E2 NCBI cM Map 4 78.96 NCBI
Pgd Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955486 3,343,863 - 3,357,066 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955486 3,344,705 - 3,356,906 (-) NCBI ChiLan1.0 ChiLan1.0
PGD Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 2 85,393,526 - 85,408,714 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 2 85,393,819 - 85,408,272 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 2 81,995,019 - 82,010,228 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 2 86,128,551 - 86,143,976 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 2 86,128,552 - 86,143,996 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 2 82,875,909 - 82,891,117 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 2 83,878,401 - 83,893,609 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 2 84,941,328 - 84,956,541 (-) NCBI UU_Cfam_GSD_1.0
Pgd Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405058 33,749,594 - 33,766,445 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936623 4,234,837 - 4,252,467 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936623 4,234,869 - 4,251,690 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
PGD Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 6 70,675,815 - 70,692,679 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 6 70,675,751 - 70,692,697 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 6 64,608,578 - 64,625,512 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3 Pig Cytomap 6 q22-q25 NCBI
PGD
Pgd
.
10053720 Scort26 Serum corticosterone level QTL 26 2.06 0.0147 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 5 124965598 166875058 Rat 631272 Lanf1 Left ventricular atrial natriuretic factor QTL 1 12 heart left ventricle natriuretic peptide A amount (VT:0010596) heart left ventricle natriuretic peptide A level (CMO:0002165) 5 151113452 166875058 Rat 1576314 Eutr1 Estrogen induced uterine response QTL 1 uterus integrity trait (VT:0010575) pyometritis severity score (CMO:0002009) 5 2138965 166875058 Rat 2302369 Scl60 Serum cholesterol level QTL 60 3.13 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 5 143608201 161165651 Rat 631562 Apr2 Acute phase response QTL 2 3.7 blood murinoglobulin 1 amount (VT:0010597) plasma murinoglobulin 1 level (CMO:0001931) 5 135927956 166875058 Rat 634349 Bp139 Blood pressure QTL 139 0.001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 5 128924607 166875058 Rat 61444 Strs2 Sensitivity to stroke QTL 2 4.7 cerebrum integrity trait (VT:0010549) post-insult time to onset of cerebrovascular lesion (CMO:0002343) 5 135929696 166875058 Rat 724525 Bp147 Blood pressure QTL 147 4.3 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 5 126424772 166875058 Rat 1549904 Neuinf1 Neuroinflammation QTL 1 3 0 nervous system integrity trait (VT:0010566) blood T lymphocyte count (CMO:0000110) 5 154828214 166875058 Rat 738018 Anxrr4 Anxiety related response QTL 4 5.1 exploratory behavior trait (VT:0010471) percentage of entries into a discrete space in an experimental apparatus (CMO:0000961) 5 130130159 166875058 Rat 2313096 Bmd78 Bone mineral density QTL 78 3.1 0.0001 tibia mineral mass (VT:1000283) total volumetric bone mineral density (CMO:0001728) 5 144377876 161317411 Rat 8552908 Pigfal4 Plasma insulin-like growth factor 1 level QTL 4 6.6 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 5 128506074 166875058 Rat 61393 Bp7 Blood pressure QTL 7 4.5 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 5 60293434 161481680 Rat 7794791 Mcs33 Mammary carcinoma susceptibility QTL 33 1.93 mammary gland integrity trait (VT:0010552) mammary tumor incidence/prevalence measurement (CMO:0000946) 5 131345754 166875058 Rat 1354631 Swd2 Spike wave discharge measurement QTL 2 3.64 0.0002 brain electrophysiology trait (VT:0010557) brain total spike-and-wave discharge duration (CMO:0001740) 5 151113452 164465185 Rat 1302790 Scl20 Serum cholesterol level QTL 20 6.4 0.0001 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 5 82394392 166664054 Rat 1598861 Cm64 Cardiac mass QTL 64 2.9 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 5 127798274 166875058 Rat 1578766 Tcas11 Tongue tumor susceptibility QTL 11 4.12 tongue integrity trait (VT:0010553) number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950) 5 46711509 161317411 Rat 631505 Bp103 Blood pressure QTL 103 3.2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 5 132717196 165560427 Rat 1641920 Colcs1 Colorectal carcinoma susceptibility QTL 1 2.99 0.0055 intestine integrity trait (VT:0010554) benign colorectal tumor surface area measurement (CMO:0001799) 5 121846814 166846814 Rat 1298090 Bp155 Blood pressure QTL 155 3.8 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 5 151006154 161165494 Rat 1598819 Bp292 Blood pressure QTL 292 4.3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 5 127798274 166875058 Rat 8694169 Bw148 Body weight QTL 148 5 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 5 128506074 166875058 Rat 1331721 Bp210 Blood pressure QTL 210 3.413 arterial blood pressure trait (VT:2000000) blood pressure time series experimental set point of the baroreceptor response (CMO:0002593) 5 143069996 166846814 Rat
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
Ensembl Acc Id:
ENSRNOT00000077784 ⟹ ENSRNOP00000074305
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 159,561,271 - 159,613,778 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000078830 ⟹ ENSRNOP00000075214
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 159,611,682 - 159,742,778 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000079919 ⟹ ENSRNOP00000075228
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 159,611,682 - 159,742,778 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000080888 ⟹ ENSRNOP00000072431
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 159,611,682 - 159,742,778 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000086226 ⟹ ENSRNOP00000077156
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 159,668,015 - 159,742,778 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000087739 ⟹ ENSRNOP00000074322
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 159,611,682 - 159,742,778 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000089099 ⟹ ENSRNOP00000075522
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 159,611,682 - 159,742,778 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000104782 ⟹ ENSRNOP00000082532
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 159,582,731 - 159,598,949 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000105558 ⟹ ENSRNOP00000094551
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 159,611,682 - 159,742,778 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000117986 ⟹ ENSRNOP00000088342
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 5 159,611,682 - 159,742,778 (-) Ensembl
RefSeq Acc Id:
NM_001305435 ⟹ NP_001292364
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 5 164,865,830 - 164,882,029 (-) NCBI mRatBN7.2 5 159,582,746 - 159,598,945 (-) NCBI Rnor_6.0 5 165,966,128 - 165,982,327 (-) NCBI Celera 5 157,853,711 - 157,869,910 (-) NCBI
Sequence:
CGCCGGGAGCCGGAGTTCACAGCACTTTCTCCGGAGCGCTCAGTCTTTTCGTGTTTCTTCCTCCTCGGATCTGCTCTGTCTACCGCCGCCATGGCCCAAGCTGACATTGCACTGATTGGACTGGCTGT
hide sequence
RefSeq Acc Id:
NP_001292364 ⟸ NM_001305435
- UniProtKB:
P85968 (UniProtKB/Swiss-Prot), A6IUA2 (UniProtKB/TrEMBL), A6IUA3 (UniProtKB/TrEMBL)
- Sequence:
MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLAKEAKGTKVIGAKSLKDMVSKLKKPRRVILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCQDLKAKGILFVGSGV
hide sequence
Ensembl Acc Id:
ENSRNOP00000072431 ⟸ ENSRNOT00000080888
Ensembl Acc Id:
ENSRNOP00000077156 ⟸ ENSRNOT00000086226
Ensembl Acc Id:
ENSRNOP00000094551 ⟸ ENSRNOT00000105558
Ensembl Acc Id:
ENSRNOP00000075214 ⟸ ENSRNOT00000078830
Ensembl Acc Id:
ENSRNOP00000088342 ⟸ ENSRNOT00000117986
Ensembl Acc Id:
ENSRNOP00000082532 ⟸ ENSRNOT00000104782
Ensembl Acc Id:
ENSRNOP00000074322 ⟸ ENSRNOT00000087739
Ensembl Acc Id:
ENSRNOP00000075522 ⟸ ENSRNOT00000089099
Ensembl Acc Id:
ENSRNOP00000075228 ⟸ ENSRNOT00000079919
Ensembl Acc Id:
ENSRNOP00000074305 ⟸ ENSRNOT00000077784
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2014-07-10
Pgd
phosphogluconate dehydrogenase
LOC100360180
6-phosphogluconate dehydrogenase, decarboxylating-like
Data merged from RGD:2322669
737654 APPROVED
2010-05-06
LOC100360180
6-phosphogluconate dehydrogenase, decarboxylating-like
Symbol and Name status set to provisional
70820 PROVISIONAL
2007-04-13
phosphogluconate dehydrogenase
Pgd
phosphogluconate dehydrogenase (mapped)
Name updated
737654 APPROVED
2007-04-11
Pgd
phosphogluconate dehydrogenase (mapped)
Pgd_mapped
phosphogluconate dehydrogenase (mapped)
Data merged from RGD:3314
737654 APPROVED
2006-11-19
Pgd
phosphogluconate dehydrogenase (mapped)
Symbol and Name status set to provisional
70820 PROVISIONAL
2005-11-17
Pgd_mapped
phosphogluconate dehydrogenase (mapped)
Symbol and Name updated
1556543 APPROVED
2003-04-09
Pgd
phosphogluconate dehydrogenase
Phosphogluconate dehydrogenase
Name updated
629478 APPROVED
2002-06-10
Pgd
Phosphogluconate dehydrogenase
Symbol and Name status set to approved
70586 APPROVED
Note Type
Note
Reference
gene_regulation
activity decreases with age in adipose tissue and kidney cortex but not skeletal muscle, heart or brain
1334488
gene_regulation
activity increased by oestradiol in females
1334488
