Gstm4 (glutathione S-transferase mu 4) - Rat Genome Database

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Gene: Gstm4 (glutathione S-transferase mu 4) Rattus norvegicus
Analyze
Symbol: Gstm4
Name: glutathione S-transferase mu 4
RGD ID: 1565825
Description: Predicted to enable several functions, including glutathione binding activity; glutathione transferase activity; and leukotriene-C4 synthase activity. Predicted to be involved in glutathione metabolic process and long-chain fatty acid biosynthetic process. Predicted to act upstream of or within nitrobenzene metabolic process and xenobiotic catabolic process. Predicted to be located in cytosol. Orthologous to human GSTM4 (glutathione S-transferase mu 4); PARTICIPATES IN glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: glutathione S-transferase M4; glutathione S-transferase mu 3; glutathione S-transferase, mu 4; GST class-mu 4; GSTM4-4; leukotriene C4 synthase GSTM4; MGC108896; similar to glutathione transferase GSTM7-7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82198,356,114 - 198,373,487 (-)NCBIGRCr8
mRatBN7.22195,667,940 - 195,685,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2195,680,004 - 195,685,323 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2203,322,478 - 203,327,732 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02201,204,594 - 201,209,850 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02196,021,555 - 196,026,811 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02210,834,013 - 210,839,242 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2210,833,884 - 210,839,295 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02230,302,889 - 230,308,113 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,605,593 - 203,610,817 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2188,325,385 - 188,330,613 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstm4Ratautistic disorder  ISOGSTM4 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
Gstm4Rathereditary spastic paraplegia 63  ISOGSTM4 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegia 63ClinVarPMID:23911318 and PMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstm4RatChemical and Drug Induced Liver Injury  ISOGSTM4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25226513
Gstm4Ratneurodegenerative disease  ISOGSTM4 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15964507

1 to 20 of 171 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstm4Rat(1->4)-beta-D-glucan multiple interactionsISOGstm4 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GSTM4 mRNACTDPMID:36331819
Gstm4Rat1,2-dichloroethane decreases expressionISOGstm4 (Mus musculus)6480464ethylene dichloride results in decreased expression of GSTM4 mRNACTDPMID:28960355
Gstm4Rat1-chloro-2,4-dinitrobenzene multiple interactionsISOGSTM4 (Homo sapiens)6480464GSTM4 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]CTDPMID:8203914
Gstm4Rat1-chloro-2,4-dinitrobenzene affects metabolic processingISOGSTM4 (Homo sapiens)6480464GSTM4 protein affects the metabolism of DinitrochlorobenzeneCTDPMID:8349586
Gstm4Rat17beta-estradiol increases expressionISOGstm4 (Mus musculus)6480464Estradiol results in increased expression of GSTM4 mRNACTDPMID:39298647
Gstm4Rat1H-pyrazole increases expressionISOGstm4 (Mus musculus)6480464pyrazole results in increased expression of GSTM4 mRNACTDPMID:17945193
Gstm4Rat2,2',4,4',5,5'-hexachlorobiphenyl increases expressionISOGstm4 (Mus musculus)64804642 more ...CTDPMID:20005886 and PMID:21851831
Gstm4Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOGstm4 (Mus musculus)64804642 more ...CTDPMID:21851831 and PMID:28433925
Gstm4Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOGstm4 (Mus musculus)64804642 more ...CTDPMID:16214954 more ...
Gstm4Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of GSTM4 mRNACTDPMID:33387578
Gstm4Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOGstm4 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of GSTM4 mRNACTDPMID:21570461
Gstm4Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOGSTM4 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of GSTM4 mRNACTDPMID:20106945 and PMID:21632981
Gstm4Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOGstm4 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of GSTM4 mRNACTDPMID:18172886 more ...
Gstm4Rat2,4,6-trinitrotoluene affects expressionEXP 6480464Trinitrotoluene affects the expression of GSTM4 mRNACTDPMID:21346803
Gstm4Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of GSTM4 mRNACTDPMID:21346803
Gstm4Rat3,3',4,4',5-pentachlorobiphenyl increases expressionISOGstm4 (Mus musculus)64804643 more ...CTDPMID:37080397
Gstm4Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of GSTM4 mRNA and alpha-Chlorohydrin results in increased expression of GSTM4 proteinCTDPMID:28522335 and PMID:34915118
Gstm4Rat4,4'-sulfonyldiphenol affects expressionISOGstm4 (Mus musculus)6480464bisphenol S affects the expression of GSTM4 mRNACTDPMID:39298647
Gstm4Rat4-amino-2,6-dinitrotoluene affects expressionEXP 64804644-amino-2 and 6-dinitrotoluene affects the expression of GSTM4 mRNACTDPMID:21346803
Gstm4Rat8'-apo-beta,psi-caroten-8'-al decreases expressionISOGSTM4 (Homo sapiens)6480464apocarotenal results in decreased expression of GSTM4 mRNACTDPMID:17034753

1 to 20 of 171 rows

Biological Process
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstm4Ratglutathione metabolic process involved_inISOGSTM4 (Homo sapiens)1624291 PMID:8373352RGDPMID:8373352
Gstm4Ratglutathione metabolic process involved_inIBAFB:FBgn0010226 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gstm4Ratglutathione metabolic process involved_inIEAUniProtKB:Q03013 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107
Gstm4Ratlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
Gstm4Ratlong-chain fatty acid biosynthetic process involved_inISSUniProtKB:Q030131600115GO_REF:0000024UniProtGO_REF:0000024
Gstm4Ratlong-chain fatty acid biosynthetic process involved_inISOGSTM4 (Homo sapiens)1624291 PMID:27791009RGDPMID:27791009
Gstm4Ratlong-chain fatty acid biosynthetic process involved_inIEAUniProtKB:Q03013 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107
Gstm4Ratnitrobenzene metabolic process acts_upstream_of_or_withinISOGstm4 (Mus musculus)1624291 PMID:12069689RGDPMID:12069689
Gstm4Ratxenobiotic catabolic process involved_inIEAUniProtKB:Q03013 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107
Gstm4Ratxenobiotic catabolic process acts_upstream_of_or_withinISOGstm4 (Mus musculus)1624291 PMID:12069689RGDPMID:12069689
Gstm4Ratxenobiotic catabolic process involved_inISOGSTM4 (Homo sapiens)1624291 PMID:8373352RGDPMID:8373352
1 to 11 of 11 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstm4Ratcytoplasm located_inIEAUniProtKB:Q03013 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107
Gstm4Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Gstm4Ratcytoplasm located_inISOGSTM4 (Homo sapiens)1624291 PMID:8373352RGDPMID:8373352
Gstm4Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Gstm4Ratcytosol located_inIEAUniProtKB:Q03013 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107
Gstm4Ratcytosol located_inISOGSTM4 (Homo sapiens) and UniProtKB:Q03013-11624291 RGDGO_REF:0000052
Gstm4Ratcytosol located_inIEAUniProtKB:A0A140VKE3 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107

Molecular Function
1 to 20 of 22 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstm4Ratenzyme binding enablesISOGSTM4 (Homo sapiens)1624291UniProtKB:Q03013 and PMID:8373352RGDPMID:8373352
Gstm4Ratenzyme binding enablesIEAUniProtKB:Q03013 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107
Gstm4Ratglutathione binding enablesIEAUniProtKB:Q03013 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107
Gstm4Ratglutathione binding enablesISOGSTM4 (Homo sapiens)1624291 PMID:8373352RGDPMID:8373352
Gstm4Ratglutathione transferase activity enablesISSUniProtKB:Q030131600115GO_REF:0000024UniProtGO_REF:0000024
Gstm4Ratglutathione transferase activity enablesISOGstm4 (Mus musculus)1624291 PMID:12069689RGDPMID:12069689
Gstm4Ratglutathione transferase activity enablesIBAFB:FBgn0010226 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gstm4Ratglutathione transferase activity enablesIEAEC:2.5.1.181600115GO_REF:0000003UniProtGO_REF:0000003
Gstm4Ratglutathione transferase activity enablesISOGSTM4 (Homo sapiens)1624291 PMID:8203914 and PMID:8373352RGDPMID:8203914 and PMID:8373352
Gstm4Ratglutathione transferase activity enablesIEAInterPro:IPR0030811600115GO_REF:0000002InterProGO_REF:0000002
Gstm4Ratglutathione transferase activity enablesIEAUniProtKB:Q03013 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107
Gstm4Ratidentical protein binding enablesIEAARBA:ARBA000279301600115GO_REF:0000117UniProtGO_REF:0000117
Gstm4Ratleukotriene-C4 synthase activity enablesISSUniProtKB:Q030131600115GO_REF:0000024UniProtGO_REF:0000024
Gstm4Ratleukotriene-C4 synthase activity enablesIEAEC:4.4.1.201600115GO_REF:0000003UniProtGO_REF:0000003
Gstm4Ratleukotriene-C4 synthase activity enablesIEARHEA:176171600115GO_REF:0000116RHEAGO_REF:0000116
Gstm4Ratleukotriene-C4 synthase activity enablesISOGSTM4 (Homo sapiens)1624291 PMID:27791009RGDPMID:27791009
Gstm4Ratleukotriene-C4 synthase activity enablesIEAUniProtKB:Q03013 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107
Gstm4Ratlyase activity enablesIEAUniProtKB-KW:KW-04561600115GO_REF:0000043UniProtGO_REF:0000043
Gstm4Ratprotein binding enablesISOGSTM4 (Homo sapiens)1624291UniProtKB:P05067 more ...RGDPMID:25416956 more ...
Gstm4Ratprotein homodimerization activity enablesIEAUniProtKB:Q03013 and ensembl:ENSP000003588511600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 22 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gstm4Ratglutathione metabolic pathway  IEA 6907045 KEGGrno:00480
Gstm4Ratphase I biotransformation pathway via cytochrome P450  IEA 6907045 KEGGrno:00980
Gstm4Ratphase I biotransformation pathway via cytochrome P450  IEA 6907045 KEGGrno:00982

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:8203914   PMID:8373352   PMID:12069689   PMID:27791009  



Gstm4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82198,356,114 - 198,373,487 (-)NCBIGRCr8
mRatBN7.22195,667,940 - 195,685,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2195,680,004 - 195,685,323 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2203,322,478 - 203,327,732 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02201,204,594 - 201,209,850 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02196,021,555 - 196,026,811 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02210,834,013 - 210,839,242 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2210,833,884 - 210,839,295 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02230,302,889 - 230,308,113 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,605,593 - 203,610,817 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2188,325,385 - 188,330,613 (-)NCBICelera
Cytogenetic Map2q34NCBI
GSTM4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381109,656,099 - 109,667,727 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1109,656,099 - 109,665,496 (+)EnsemblGRCh38hg38GRCh38
GRCh371110,198,721 - 110,208,119 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361110,000,226 - 110,009,648 (+)NCBINCBI36Build 36hg18NCBI36
Celera1108,463,772 - 108,473,180 (+)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1108,086,984 - 108,096,416 (+)NCBIHuRef
CHM1_11110,313,519 - 110,322,944 (+)NCBICHM1_1
T2T-CHM13v2.01109,684,537 - 109,696,166 (+)NCBIT2T-CHM13v2.0
Gstm4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393107,937,887 - 107,952,495 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3107,947,724 - 107,952,210 (-)EnsemblGRCm39 Ensembl
GRCm383108,030,571 - 108,045,179 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3108,040,408 - 108,044,894 (-)EnsemblGRCm38mm10GRCm38
MGSCv373107,843,326 - 107,847,777 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363108,168,464 - 108,172,845 (-)NCBIMGSCv36mm8
Celera3110,373,991 - 110,378,442 (-)NCBICelera
Cytogenetic Map3F2.3NCBI
cM Map346.83NCBI
Gstm4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543513,063,966 - 13,210,264 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543513,064,691 - 13,069,734 (+)NCBIChiLan1.0ChiLan1.0
GSTM4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21117,629,559 - 117,648,713 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11116,774,969 - 116,808,377 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01112,033,462 - 112,337,606 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11111,261,585 - 111,270,912 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1111,261,585 - 111,270,919 (+)Ensemblpanpan1.1panPan2
LOC479912
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1642,201,697 - 42,207,886 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha644,977,327 - 44,983,514 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0642,533,367 - 42,539,560 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl642,534,290 - 42,539,704 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1642,266,138 - 42,272,342 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0642,223,891 - 42,230,078 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0642,658,872 - 42,665,063 (-)NCBIUU_Cfam_GSD_1.0
LOC101958900
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505818,963,655 - 18,971,183 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367041,143,010 - 1,148,567 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367041,142,990 - 1,150,491 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC106510200
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.14110,378,016 - 110,413,483 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24120,750,531 - 120,784,580 (-)NCBISscrofa10.2Sscrofa10.2susScr3

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Variants in Gstm4
125 total Variants

Predicted Target Of
Summary Value
Count of predictions:123
Count of miRNA genes:99
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000025994
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 65 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2122609194206936711Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat

1 to 10 of 65 rows
RH129190  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22195,680,036 - 195,680,249 (+)MAPPERmRatBN7.2
Rnor_6.02210,834,052 - 210,834,264NCBIRnor6.0
Rnor_5.02230,302,923 - 230,303,135UniSTSRnor5.0
RGSC_v3.42203,605,627 - 203,605,839UniSTSRGSC3.4
Celera2188,325,419 - 188,325,631UniSTS
RH 3.4 Map21389.7UniSTS
Cytogenetic Map2q34UniSTS
RH137064  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22195,680,084 - 195,680,280 (+)MAPPERmRatBN7.2
Rnor_6.02210,834,100 - 210,834,295NCBIRnor6.0
Rnor_5.02230,302,971 - 230,303,166UniSTSRnor5.0
RGSC_v3.42203,605,675 - 203,605,870UniSTSRGSC3.4
Celera2188,325,467 - 188,325,662UniSTS
RH 3.4 Map21390.2UniSTS
Cytogenetic Map2q34UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000025994   ⟹   ENSRNOP00000025994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2195,680,004 - 195,685,282 (-)Ensembl
Rnor_6.0 Ensembl2210,833,884 - 210,839,295 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106805   ⟹   ENSRNOP00000078318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2195,680,004 - 195,685,282 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119188   ⟹   ENSRNOP00000091974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2195,680,013 - 195,685,323 (-)Ensembl
RefSeq Acc Id: NM_001024304   ⟹   NP_001019475
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,368,159 - 198,373,383 (-)NCBI
mRatBN7.22195,680,003 - 195,685,227 (-)NCBI
Rnor_6.02210,834,018 - 210,839,242 (-)NCBI
Rnor_5.02230,302,889 - 230,308,113 (-)NCBI
RGSC_v3.42203,605,593 - 203,610,817 (-)RGD
Celera2188,325,385 - 188,330,613 (-)RGD
Sequence:
RefSeq Acc Id: XM_039102935   ⟹   XP_038958863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,368,159 - 198,373,487 (-)NCBI
mRatBN7.22195,680,013 - 195,685,281 (-)NCBI
RefSeq Acc Id: XM_039102936   ⟹   XP_038958864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,368,159 - 198,373,471 (-)NCBI
mRatBN7.22195,680,231 - 195,685,281 (-)NCBI
RefSeq Acc Id: XM_039102937   ⟹   XP_038958865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,356,114 - 198,373,444 (-)NCBI
mRatBN7.22195,667,940 - 195,685,281 (-)NCBI
RefSeq Acc Id: XM_039102940   ⟹   XP_038958868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,368,159 - 198,373,330 (-)NCBI
mRatBN7.22195,680,231 - 195,685,315 (-)NCBI
RefSeq Acc Id: XM_063282402   ⟹   XP_063138472
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,370,629 - 198,373,444 (-)NCBI
RefSeq Acc Id: XM_063282403   ⟹   XP_063138473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,368,159 - 198,373,134 (-)NCBI
RefSeq Acc Id: XM_063282404   ⟹   XP_063138474
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,370,629 - 198,373,444 (-)NCBI
1 to 5 of 11 rows
1 to 5 of 11 rows
RefSeq Acc Id: NP_001019475   ⟸   NM_001024304
- UniProtKB: Q5BK56 (UniProtKB/TrEMBL),   B6DYQ3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025994   ⟸   ENSRNOT00000025994
RefSeq Acc Id: XP_038958865   ⟸   XM_039102937
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038958863   ⟸   XM_039102935
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038958868   ⟸   XM_039102940
- Peptide Label: isoform X5
- UniProtKB: A6HUX5 (UniProtKB/TrEMBL)
GST C-terminal   GST N-terminal

Name Modeler Protein Id AA Range Protein Structure
AF-Q5BK56-F1-model_v2 AlphaFold Q5BK56 1-218 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691670
Promoter ID:EPDNEW_R2195
Type:initiation region
Name:Gstm4_1
Description:glutathione S-transferase mu 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02210,839,230 - 210,839,290EPDNEW


1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-51640 BioCyc
Ensembl Genes ENSRNOG00000019221 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025939 ENTREZGENE
  ENSRNOT00000025994.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1050.10 UniProtKB/Swiss-Prot
  Glutaredoxin UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7379741 IMAGE-MGC_LOAD
InterPro Glutathione-S-Trfase_C-like UniProtKB/Swiss-Prot
  Glutathione-S-Trfase_C_sf UniProtKB/Swiss-Prot
  Glutathione_S-Trfase_N UniProtKB/Swiss-Prot
  GST_C UniProtKB/Swiss-Prot
  GST_mu UniProtKB/Swiss-Prot
  GST_superfamily UniProtKB/Swiss-Prot
  Thioredoxin-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:499689 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108896 IMAGE-MGC_LOAD
NCBI Gene 499689 ENTREZGENE
PANTHER GLUTATHIONE S-TRANSFERASE UniProtKB/Swiss-Prot
  GLUTATHIONE S-TRANSFERASE MU 4 UniProtKB/Swiss-Prot
Pfam GST_C UniProtKB/Swiss-Prot
  GST_N UniProtKB/Swiss-Prot
PhenoGen Gstm4 PhenoGen
PRINTS GSTRNSFRASEM UniProtKB/Swiss-Prot
PROSITE GST_CTER UniProtKB/Swiss-Prot
  GST_NTER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019221 RatGTEx
Superfamily-SCOP SSF47616 UniProtKB/Swiss-Prot
  SSF52833 UniProtKB/Swiss-Prot
UniProt A0A8I5ZKM2_RAT UniProtKB/TrEMBL
  A0A8I6AGM9_RAT UniProtKB/TrEMBL
  A6HUX5 ENTREZGENE, UniProtKB/TrEMBL
  B6DYQ3 ENTREZGENE, UniProtKB/TrEMBL
  GSTM4_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Gstm4  glutathione S-transferase mu 4  LOC100196943  glutathione S-transferase mu 3  Data merged from RGD:2302156 1643240 APPROVED
2009-02-04 Gstm4  glutathione S-transferase mu 4  Gstm4  glutathione S-transferase M4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-21 LOC100196943  glutathione S-transferase mu 3      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-11-03 Gstm4  glutathione S-transferase M4  Gstm4  glutathione S-transferase, mu 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Gstm4  glutathione S-transferase, mu 4  MGC108896  similar to glutathione transferase GSTM7-7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 MGC108896  similar to glutathione transferase GSTM7-7      Symbol and Name status set to provisional 70820 PROVISIONAL