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Gene: Usp50 (ubiquitin specific peptidase 50) Rattus norvegicus

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Symbol:

Usp50

Name:

ubiquitin specific peptidase 50

RGD ID:

1564751

Description:

Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in Ras protein signal transduction; endosome organization; and regulation of cell cycle G2/M phase transition. Predicted to act upstream of or within several processes, including nuclear speck organization; positive regulation of NLRP3 inflammasome complex assembly; and positive regulation of cytokine production. Predicted to be located in centrosome; cytoplasm; and nucleus. Predicted to be active in cytosol; midbody; and postsynaptic density. Orthologous to human USP50 (ubiquitin specific peptidase 50); INTERACTS WITH bisphenol A; paracetamol; trichloroethene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

inactive ubiquitin carboxyl-terminal hydrolase 50; LOC311399; RGD1564751; similar to RIKEN cDNA 4930511O11

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	USP50 (ubiquitin specific peptidase 50)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Treefam
Mus musculus (house mouse):	Usp50 (ubiquitin specific peptidase 50)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Usp50 (ubiquitin specific peptidase 50)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	USP50 (ubiquitin specific peptidase 50)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	USP50 (ubiquitin specific peptidase 50)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Usp50 (ubiquitin specific peptidase 50)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	USP50 (ubiquitin specific peptidase 50)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	USP50 (ubiquitin specific peptidase 50)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	USP50 (ubiquitin specific peptidase 50)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Usp50 (ubiquitin specific peptidase 50)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	usp-50	Alliance	DIOPT (Ensembl Compara\|OrthoInspector)
Saccharomyces cerevisiae (baker's yeast):	UBP5	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	134,465,469 - 134,488,859 (-)	NCBI		GRCr8
mRatBN7.2	3	114,012,104 - 114,035,468 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	114,011,702 - 114,035,476 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	3	119,225,055 - 119,247,442 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	119,224,943 - 119,247,449 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	125,748,984 - 125,772,328 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	114,287,018 - 114,309,429 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	112,854,521 - 112,875,759 (-)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp50	Rat	Bloom syndrome		ISO	USP50 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Bloom syndrome	ClinVar	PMID:28492532
Usp50	Rat	colorectal cancer		ISO	USP50 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Familial colorectal cancer	ClinVar	PMID:28492532
Usp50	Rat	hereditary spastic paraplegia		ISO	USP50 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hereditary spastic paraplegia	ClinVar	PMID:25741868 and PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp50	Rat	17beta-estradiol	decreases expression	ISO	Usp50 (Mus musculus)	6480464	Estradiol results in decreased expression of USP50 mRNA	CTD	PMID:39298647
Usp50	Rat	2,3',4,4',5-Pentachlorobiphenyl	affects expression	ISO	Usp50 (Mus musculus)	6480464	2 more ...	CTD	PMID:31388691
Usp50	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Usp50 (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of USP50 mRNA	CTD	PMID:26377647
Usp50	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	Usp50 (Mus musculus)	6480464	bisphenol S results in decreased expression of USP50 mRNA	CTD	PMID:39298647
Usp50	Rat	benzo[a]pyrene	increases methylation	ISO	USP50 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of USP50 5' UTR	CTD	PMID:27901495
Usp50	Rat	bis(2-ethylhexyl) phthalate	increases expression	ISO	Usp50 (Mus musculus)	6480464	Diethylhexyl Phthalate results in increased expression of USP50 mRNA	CTD	PMID:33754040
Usp50	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of USP50 mRNA	CTD	PMID:25181051
Usp50	Rat	bisphenol A	decreases expression	ISO	Usp50 (Mus musculus)	6480464	bisphenol A results in decreased expression of USP50 mRNA	CTD	PMID:32156529
Usp50	Rat	butanal	decreases expression	ISO	USP50 (Homo sapiens)	6480464	butyraldehyde results in decreased expression of USP50 mRNA	CTD	PMID:26079696
Usp50	Rat	cadmium atom	decreases expression	ISO	USP50 (Homo sapiens)	6480464	Cadmium results in decreased expression of USP50 mRNA	CTD	PMID:24376830
Usp50	Rat	CGP 52608	multiple interactions	ISO	USP50 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to USP50 gene]	CTD	PMID:28238834
Usp50	Rat	leflunomide	decreases expression	ISO	USP50 (Homo sapiens)	6480464	leflunomide results in decreased expression of USP50 mRNA	CTD	PMID:28988120
Usp50	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of USP50 mRNA	CTD	PMID:33387578
Usp50	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	Usp50 (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of USP50 mRNA	CTD	PMID:36331819
Usp50	Rat	raloxifene	multiple interactions	ISO	Usp50 (Mus musculus)	6480464	[SOD1 protein mutant form affects the susceptibility to Raloxifene Hydrochloride] which results in decreased expression of USP50 mRNA	CTD	PMID:33269387
Usp50	Rat	raloxifene	increases expression	ISO	Usp50 (Mus musculus)	6480464	Raloxifene Hydrochloride results in increased expression of USP50 mRNA	CTD	PMID:33269387
Usp50	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of USP50 mRNA	CTD	PMID:33387578

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp50	Rat	endosome organization	involved_in	IBA	MGI:1934029 and PANTHER:PTN008578257	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp50	Rat	nuclear speck organization	acts_upstream_of_or_within	ISO	USP50 (Homo sapiens)	1624291	PMID:28094437	RGD	PMID:28094437
Usp50	Rat	nuclear speck organization	acts_upstream_of_or_within	IEA	UniProtKB:Q70EL3 and ensembl:ENSP00000434676	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	positive regulation of interleukin-1 beta production	acts_upstream_of_or_within	ISO	USP50 (Homo sapiens)	1624291	PMID:28094437	RGD	PMID:28094437
Usp50	Rat	positive regulation of interleukin-1 beta production	acts_upstream_of_or_within	IEA	UniProtKB:Q6P8X6 and ensembl:ENSMUSP00000028842	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	positive regulation of interleukin-1 beta production	acts_upstream_of_or_within	ISO	Usp50 (Mus musculus)	1624291	PMID:28094437	RGD	PMID:28094437
Usp50	Rat	positive regulation of interleukin-1 beta production	acts_upstream_of_or_within	IEA	UniProtKB:Q70EL3 and ensembl:ENSP00000434676	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	positive regulation of interleukin-18 production	acts_upstream_of_or_within	IEA	UniProtKB:Q6P8X6 and ensembl:ENSMUSP00000028842	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	positive regulation of interleukin-18 production	acts_upstream_of_or_within	ISO	Usp50 (Mus musculus)	1624291	PMID:28094437	RGD	PMID:28094437
Usp50	Rat	positive regulation of NLRP3 inflammasome complex assembly	acts_upstream_of_or_within	ISO	USP50 (Homo sapiens)	1624291	PMID:28094437	RGD	PMID:28094437
Usp50	Rat	positive regulation of NLRP3 inflammasome complex assembly	acts_upstream_of_or_within	IEA	UniProtKB:Q70EL3 and ensembl:ENSP00000434676	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	positive regulation of NLRP3 inflammasome complex assembly	acts_upstream_of_or_within	IEA	UniProtKB:Q6P8X6 and ensembl:ENSMUSP00000028842	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	positive regulation of NLRP3 inflammasome complex assembly	acts_upstream_of_or_within	ISO	Usp50 (Mus musculus)	1624291	PMID:28094437	RGD	PMID:28094437
Usp50	Rat	protein deubiquitination	acts_upstream_of_or_within	ISO	USP50 (Homo sapiens)	1624291	PMID:28094437	RGD	PMID:28094437
Usp50	Rat	protein deubiquitination	acts_upstream_of_or_within	IEA	UniProtKB:Q70EL3 and ensembl:ENSP00000434676	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	protein deubiquitination	involved_in	IEA	InterPro:IPR001394	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Usp50	Rat	proteolysis	involved_in	IEA	UniProtKB-KW:KW-0645	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp50	Rat	Ras protein signal transduction	involved_in	IBA	MGI:1934029 and PANTHER:PTN008578257	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp50	Rat	regulation of cell cycle G2/M phase transition	involved_in	ISO	USP50 (Homo sapiens)	1624291	PMID:20930503	RGD	PMID:20930503
Usp50	Rat	regulation of cell cycle G2/M phase transition	involved_in	IEA	UniProtKB:Q70EL3 and ensembl:ENSP00000434676	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp50	Rat	centrosome	located_in	IEA	UniProtKB:Q70EL3 and ensembl:ENSP00000434676	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	centrosome	located_in	ISO	USP50 (Homo sapiens)	1624291	PMID:20930503	RGD	PMID:20930503
Usp50	Rat	cytoplasm	located_in	ISO	USP50 (Homo sapiens)	1624291	PMID:20930503	RGD	PMID:20930503
Usp50	Rat	cytoplasm	located_in	IEA	UniProtKB:Q70EL3 and ensembl:ENSP00000434676	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	cytosol	is_active_in	IBA	MGI:1934029 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp50	Rat	midbody	is_active_in	IBA	MGI:1934029 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp50	Rat	nucleus	located_in	ISO	USP50 (Homo sapiens)	1624291	PMID:20930503	RGD	PMID:20930503
Usp50	Rat	nucleus	located_in	IEA	UniProtKB:Q70EL3 and ensembl:ENSP00000434676	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	postsynaptic density	is_active_in	IBA	PANTHER:PTN008371010 and Usp8 (Rattus norvegicus)	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp50	Rat	cysteine-type deubiquitinase activity	enables	IEA	UniProtKB:Q70EL3 and ensembl:ENSP00000434676	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp50	Rat	cysteine-type deubiquitinase activity	enables	IEA	InterPro:IPR001394 and InterPro:IPR018200	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Usp50	Rat	cysteine-type deubiquitinase activity	enables	IEA	UniRule:UR000880756	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Usp50	Rat	cysteine-type deubiquitinase activity	enables	IEA	EC:3.4.19.12	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Usp50	Rat	cysteine-type deubiquitinase activity	enables	IBA	MGI:1934029 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp50	Rat	cysteine-type deubiquitinase activity	enables	ISO	USP50 (Homo sapiens)	1624291	PMID:28094437 and PMID:36876523	RGD	PMID:28094437 and PMID:36876523
Usp50	Rat	cysteine-type peptidase activity	enables	IEA	UniProtKB-KW:KW-0788	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp50	Rat	hydrolase activity	enables	IEA	UniProtKB-KW:KW-0378	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp50	Rat	peptidase activity	enables	IEA	UniProtKB-KW:KW-0645	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp50	Rat	protein binding	enables	ISO	Usp50 (Mus musculus)	1624291	UniProtKB:Q9ULZ3 and PMID:28094437	RGD	PMID:28094437
Usp50	Rat	ubiquitin-like protein peptidase activity	enables	ISO	USP50 (Homo sapiens)	1624291	PMID:28094437	RGD	PMID:28094437
Usp50	Rat	ubiquitin-like protein peptidase activity	enables	IEA	UniProtKB:Q70EL3 and ensembl:ENSP00000434676	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:28094437

Usp50
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	134,465,469 - 134,488,859 (-)	NCBI		GRCr8
mRatBN7.2	3	114,012,104 - 114,035,468 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	114,011,702 - 114,035,476 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	3	119,225,055 - 119,247,442 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	119,224,943 - 119,247,449 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	125,748,984 - 125,772,328 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	114,287,018 - 114,309,429 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	112,854,521 - 112,875,759 (-)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

USP50
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	50,493,025 - 50,546,666 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	50,494,018 - 50,546,708 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	50,792,759 - 50,838,863 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	48,580,051 - 48,626,194 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	48,580,257 - 48,626,014	NCBI
Celera	15	27,685,337 - 27,731,467 (-)	NCBI		Celera
Cytogenetic Map	15	q21.2	NCBI
HuRef	15	27,623,165 - 27,669,780 (-)	NCBI		HuRef
CHM1_1	15	50,910,768 - 50,956,857 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	48,301,170 - 48,354,744 (-)	NCBI		T2T-CHM13v2.0

Usp50
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	126,602,970 - 126,625,380 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	126,551,016 - 126,625,390 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	126,761,050 - 126,783,460 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	126,709,096 - 126,783,470 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	126,586,786 - 126,609,196 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	126,452,863 - 126,474,885 (-)	NCBI		MGSCv36	mm8
Celera	2	128,000,895 - 128,023,332 (-)	NCBI		Celera
Cytogenetic Map	2	F1	NCBI
cM Map	2	61.76	NCBI

Usp50
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	3,788,903 - 3,837,983 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	3,788,723 - 3,838,077 (+)	NCBI	ChiLan1.0	ChiLan1.0

USP50
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	39,745,847 - 39,795,165 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	43,926,984 - 43,975,639 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	29,450,804 - 29,500,515 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	47,790,100 - 47,839,619 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	47,790,100 - 47,839,619 (-)	Ensembl	panpan1.1		panPan2

USP50
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	16,409,293 - 16,453,788 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	16,409,294 - 16,453,728 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	16,335,379 - 16,379,877 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	16,553,219 - 16,597,774 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	16,553,220 - 16,597,711 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	16,475,706 - 16,520,238 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	16,593,382 - 16,638,297 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	16,699,584 - 16,744,702 (-)	NCBI		UU_Cfam_GSD_1.0

Usp50
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	94,674,256 - 94,704,277 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	12,521,731 - 12,552,346 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	12,522,361 - 12,552,611 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

USP50
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	121,273,043 - 121,307,075 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	121,272,977 - 121,307,029 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	134,712,715 - 134,746,794 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

USP50
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	32,785,817 - 32,830,148 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	108,323,179 - 108,370,400 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants in Usp50
211 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	98
Count of miRNA genes:	89
Interacting mature miRNAs:	90
Transcripts:	ENSRNOT00000015238
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
1582216	Bw65	Body weight QTL 65	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	102200529	115665732	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582219	Bw63	Body weight QTL 63	3.8	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	3	96127817	115665732	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	84091273	129091273	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	112681431	157681431	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	80800231	114297550	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	97084464	142084464	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	107693393	152693393	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	112287552	135181505	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat

AU049763

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	114,036,638 - 114,036,756 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	119,248,612 - 119,248,729	NCBI	Rnor6.0
Rnor_5.0	3	125,773,503 - 125,773,620	UniSTS	Rnor5.0
RGSC_v3.4	3	114,310,811 - 114,310,928	UniSTS	RGSC3.4
Celera	3	112,876,929 - 112,877,048	UniSTS
Cytogenetic Map	3	q36	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	16	54	54	53	24	25	24	5	112	60	35	11	38	29


RefSeq Transcripts	NM_001430435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001430436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003749567	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063284983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000015238 ⟹ ENSRNOP00000015238

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	114,011,702 - 114,035,476 (-)	Ensembl
Rnor_6.0 Ensembl	3	119,224,943 - 119,247,449 (-)	Ensembl

RefSeq Acc Id:

XM_003749567 ⟹ XP_003749615

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	134,465,469 - 134,488,859 (-)	NCBI
mRatBN7.2	3	114,012,104 - 114,035,468 (-)	NCBI
Rnor_6.0	3	119,225,055 - 119,247,442 (-)	NCBI
Rnor_5.0	3	125,748,984 - 125,772,328 (-)	NCBI

Sequence:

show sequence

ATTGTGATGCAGGGGAGGACCCAAGAGGAACCAGGCTTGAGTTCAGTGAAGTCAGAAAAGTAGGGAAAAGTGGAAAGTAGAGAAAAAGGGGGAAGGCGTTCAAACTGTTCAAAAACAAAAACAAGCCA
GGGGAACAGTTTTGGAGAAATGAAGTTAAAAGGCTCACAGTTAGCTTGTGAGTAGAAGTGAAAGCCCGATGTGCTCCCAGGAACATGGCGTCTCATCGGCCGTTCCCTGCAGATGACTTCGGTGCCTA
CTACATCCTTGCGGAGTGTGCAGACTATGACTCCCTTCCGGAGTCTGAGACCCAGCCACACTTCCAGGGCGTGACGGGACTGCGGAACCTGGGCAACACCTGCTACATGAACGCCATCTTGCAGTGCC
TCTGCAGCACATCTCCACTGGTGGAGTACTTCCTGTCCGGAAAGTACATCACGGCTCTTCAGAAGGACTGCAGCGAGGTCACCACGGCCTTTGCCTACCTGATGACAGACATGTGGCTTGGCGACTCA
GACTGTGTCTCCCCAGAGATATTTCTGTCGGCTGTTGGCAGCCTTTACCCAGCCTTTCTGAAAAAGACACAGCAAGATGCGCAGGAGTTCCTGATTTACGTCCTCAACGAGCTTCATGAAGCTTTGAA
AAAGCACTGCCGAGGAAGAGCGAGTGAGAAAAGAACAGCCCAAAACTGCTGCAGGAAAGTGCCAGCCCATGAGACCTCAATCATCACCCGGCTGTTTGAAGGGCAGCTCAGTTACAGCATCACGTGTT
TAAAGTGTGAGACCTGCACCTACAAGAACGAAGTTTTCACCATCCTTTCCCTCCCCATCCCATCGGAATACGAATGCTCCCTCCAGGACTGTCTCCAGTGTTTTTTCCAACAAGACACACTGACCTGG
AACAACCAAATCCATTGTTCCTTTTGTGAAATCAAGCAAGAAACAGCTGTGAGGACCACTATTTCCAAGGCACCAAAAATAATTGTTCTTCACTTAAAAAGGTTTGACATCCAGGGTGCAGTAAAGAA
GAAGCTGAGGACAGATATTCATTACCCACTGACCAACCTGGACCTCACTCCTTATATCTGTCCAGTCTTCCGGAAACATCCCAAGTACAACCTGTGTGCAGTTGTGAACCACTTTGGAGATCTGGATG
GTGGCCACTACACTGCCTTCTGCAAGAACTCAGTAACTCAGGCCTGGTATAGTTTTGACGACACCCGAGTCAGTGAGATTCCAGATACTTCTGTTCAAACAGCCACAGCTTATCTTTTATTCTATAGC
TGCCAGCCTTTTTCTATCCCAACACAGAAGCGCAAGAGCTGGGACAGCACTCCTGATTACGGCAAGCCAGCCGTCAGGAAGTGGCCGTGAATATGCTTTGTTATTAAATCCTTCCCACCTACTCACAT
CGCTAAGGTTTGTACGTCTCACAGACAGCCTCTCTAAAACAAGTCTGC

hide sequence

RefSeq Acc Id:

XM_006234941 ⟹ XP_006235003

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	134,465,469 - 134,488,576 (-)	NCBI
mRatBN7.2	3	114,012,104 - 114,035,467 (-)	NCBI
Rnor_6.0	3	119,225,055 - 119,247,442 (-)	NCBI
Rnor_5.0	3	125,748,984 - 125,772,328 (-)	NCBI

Sequence:

show sequence

ATTGTGATGCAGGGGAGGACCCAAGAGGAACCAGGCTTGAGTTCAGTGAAGTCAGAAAAGTAGG
GAAAAGTGGAAAGTAGAGAAAAAGGGGGAAGGCGTTCAAACTGTTCAAAAACAAAAACAAGCCAGGGGAACAGTTTTGGAGAAATGAAGTTAAAAGGCTCACAGTTAGCTTGTGAGTAGAAGTGAAAG
CCCGATGTGCTCCCAGGAACATGGCGTCTCATCGGCCGTTCCCTGCAGATGACTTCGGTGCCTACTACATCCTGTGAGCCTCAAACCCTGTGCCTTTATAGATAACCTTAACAGTGGGGGGCCTTACC
CAGAGGAGCGTGGCGCCTGTTGCATTTGGGAGGGCTCTGCCAGATTTGGCCCATGAAGGACCCACAAGAGAGGTTGCCAGGGCCTGACTGGTACTAGCACTCACTCTTCCCTGGAAACACTCTCCTTC
CATGTGGCCCACACAGTGCGGAGTGTGCAGACTATGACTCCCTTCCGGAGTCTGAGACCCAGCCACACTTCCAGGGCGTGACGGGACTGCGGAACCTGGGCAACACCTGCTACATGAACGCCATCTTG
CAGTGCCTCTGCAGCACATCTCCACTGGTGGAGTACTTCCTGTCCGGAAAGTACATCACGGCTCTTCAGAAGGACTGCAGCGAGGTCACCACGGCCTTTGCCTACCTGATGACAGACATGTGGCTTGG
CGACTCAGACTGTGTCTCCCCAGAGATATTTCTGTCGGCTGTTGGCAGCCTTTACCCAGCCTTTCTGAAAAAGACACAGCAAGATGCGCAGGAGTTCCTGATTTACGTCCTCAACGAGCTTCATGAAG
CTTTGAAAAAGCACTGCCGAGGAAGAGCGAGTGAGAAAAGAACAGCCCAAAACTGCTGCAGGAAAGTGCCAGCCCATGAGACCTCAATCATCACCCGGCTGTTTGAAGGGCAGCTCAGTTACAGCATC
ACGTGTTTAAAGTGTGAGACCTGCACCTACAAGAACGAAGTTTTCACCATCCTTTCCCTCCCCATCCCATCGGAATACGAATGCTCCCTCCAGGACTGTCTCCAGTGTTTTTTCCAACAAGACACACT
GACCTGGAACAACCAAATCCATTGTTCCTTTTGTGAAATCAAGCAAGAAACAGCTGTGAGGACCACTATTTCCAAGGCACCAAAAATAATTGTTCTTCACTTAAAAAGGTTTGACATCCAGGGTGCAG
TAAAGAAGAAGCTGAGGACAGATATTCATTACCCACTGACCAACCTGGACCTCACTCCTTATATCTGTCCAGTCTTCCGGAAACATCCCAAGTACAACCTGTGTGCAGTTGTGAACCACTTTGGAGAT
CTGGATGGTGGCCACTACACTGCCTTCTGCAAGAACTCAGTAACTCAGGCCTGGTATAGTTTTGACGACACCCGAGTCAGTGAGATTCCAGATACTTCTGTTCAAACAGCCACAGCTTATCTTTTATT
CTATAGCTGCCAGCCTTTTTCTATCCCAACACAGAAGCGCAAGAGCTGGGACAGCACTCCTGATTACGGCAAGCCAGCCGTCAGGAAGTGGCCGTGAATATGCTTTGTTATTAAATCCTTCCCACCTA
CTCACATCGCTAAGGTTTGTACGTCTCACAGACAGCCTCTCTAAAACAAGTCTGC

hide sequence

RefSeq Acc Id:

XM_006234942 ⟹ XP_006235004

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	134,465,469 - 134,488,578 (-)	NCBI
mRatBN7.2	3	114,012,104 - 114,035,467 (-)	NCBI
Rnor_6.0	3	119,225,055 - 119,247,442 (-)	NCBI
Rnor_5.0	3	125,748,984 - 125,772,328 (-)	NCBI

Sequence:

show sequence

ATTGTGATGCAGGGGAGGACCCAAGAGGAACCAGGCTTGAGTTCAGTGAAGTCAGAAAAGTAGG
GAAAAGTGGAAAGTAGAGAAAAAGGGGGAAGGCGTTCAAACTGTTCAAAAACAAAAACAAGCCAGGGGAACAGTTTTGGAGAAATGAAGTTAAAAGGCTCACAGTTAGCTTGTGAGTAGAAGTGAAAG
CCCGATGTGCTCCCAGGAACATGGCGTCTCATCGGCCGTTCCCTGCAGATGACTTCGGTGCCTACTACATCCTGTGAGCCTCAAACCCTGTGCCTTTATAGATAACCTTAACAGTGGGGGGCCTTACC
CAGAGGAGCGTGGCGCCTGTTGCATTTGGGAGGGCTCTGCCAGATTTGGCCCATGAAGGACCCACAAGAGTGCGGAGTGTGCAGACTATGACTCCCTTCCGGAGTCTGAGACCCAGCCACACTTCCAG
GGCGTGACGGGACTGCGGAACCTGGGCAACACCTGCTACATGAACGCCATCTTGCAGTGCCTCTGCAGCACATCTCCACTGGTGGAGTACTTCCTGTCCGGAAAGTACATCACGGCTCTTCAGAAGGA
CTGCAGCGAGGTCACCACGGCCTTTGCCTACCTGATGACAGACATGTGGCTTGGCGACTCAGACTGTGTCTCCCCAGAGATATTTCTGTCGGCTGTTGGCAGCCTTTACCCAGCCTTTCTGAAAAAGA
CACAGCAAGATGCGCAGGAGTTCCTGATTTACGTCCTCAACGAGCTTCATGAAGCTTTGAAAAAGCACTGCCGAGGAAGAGCGAGTGAGAAAAGAACAGCCCAAAACTGCTGCAGGAAAGTGCCAGCC
CATGAGACCTCAATCATCACCCGGCTGTTTGAAGGGCAGCTCAGTTACAGCATCACGTGTTTAAAGTGTGAGACCTGCACCTACAAGAACGAAGTTTTCACCATCCTTTCCCTCCCCATCCCATCGGA
ATACGAATGCTCCCTCCAGGACTGTCTCCAGTGTTTTTTCCAACAAGACACACTGACCTGGAACAACCAAATCCATTGTTCCTTTTGTGAAATCAAGCAAGAAACAGCTGTGAGGACCACTATTTCCA
AGGCACCAAAAATAATTGTTCTTCACTTAAAAAGGTTTGACATCCAGGGTGCAGTAAAGAAGAAGCTGAGGACAGATATTCATTACCCACTGACCAACCTGGACCTCACTCCTTATATCTGTCCAGTC
TTCCGGAAACATCCCAAGTACAACCTGTGTGCAGTTGTGAACCACTTTGGAGATCTGGATGGTGGCCACTACACTGCCTTCTGCAAGAACTCAGTAACTCAGGCCTGGTATAGTTTTGACGACACCCG
AGTCAGTGAGATTCCAGATACTTCTGTTCAAACAGCCACAGCTTATCTTTTATTCTATAGCTGCCAGCCTTTTTCTATCCCAACACAGAAGCGCAAGAGCTGGGACAGCACTCCTGATTACGGCAAGC
CAGCCGTCAGGAAGTGGCCGTGAATATGCTTTGTTATTAAATCCTTCCCACCTACTCACATCGCTAAGGTTTGTACGTCTCACAGACAGCCTCTCTAAAACAAGTCTGC

hide sequence

RefSeq Acc Id:

XM_006234943 ⟹ XP_006235005

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	134,465,469 - 134,488,830 (-)	NCBI
mRatBN7.2	3	114,012,104 - 114,035,467 (-)	NCBI
Rnor_6.0	3	119,225,055 - 119,247,442 (-)	NCBI
Rnor_5.0	3	125,748,984 - 125,772,328 (-)	NCBI

Sequence:

show sequence

ATTGTGATGCAGGGGAGGACCCAAGAGGAACCAGGCTTGAGTTCAGTGAAGTCAGAAAAGTAGGGAAAAGTGGAAAGTAGAGAAAAAGGGGGAAGGCGTTCAAACTGTTCAAAAACAAAAACAAGCCA
GGGGAACAGTTTTGGAGAAATGAAGTTAAAAGGCTCACAGTTAGCTTGTGAGTAGAAGTGAAAGCCCGATGTGCTCCCAGGAACATGGCGTCTCATCGGCCGTTCCCTGCAGATGACTTCGGTGCCTA
CTACATCCTGGCGTGACGGGACTGCGGAACCTGGGCAACACCTGCTACATGAACGCCATCTTGCAGTGCCTCTGCAGCACATCTCCACTGGTGGAGTACTTCCTGTCCGGAAAGTACATCACGGCTCT
TCAGAAGGACTGCAGCGAGGTCACCACGGCCTTTGCCTACCTGATGACAGACATGTGGCTTGGCGACTCAGACTGTGTCTCCCCAGAGATATTTCTGTCGGCTGTTGGCAGCCTTTACCCAGCCTTTC
TGAAAAAGACACAGCAAGATGCGCAGGAGTTCCTGATTTACGTCCTCAACGAGCTTCATGAAGCTTTGAAAAAGCACTGCCGAGGAAGAGCGAGTGAGAAAAGAACAGCCCAAAACTGCTGCAGGAAA
GTGCCAGCCCATGAGACCTCAATCATCACCCGGCTGTTTGAAGGGCAGCTCAGTTACAGCATCACGTGTTTAAAGTGTGAGACCTGCACCTACAAGAACGAAGTTTTCACCATCCTTTCCCTCCCCAT
CCCATCGGAATACGAATGCTCCCTCCAGGACTGTCTCCAGTGTTTTTTCCAACAAGACACACTGACCTGGAACAACCAAATCCATTGTTCCTTTTGTGAAATCAAGCAAGAAACAGCTGTGAGGACCA
CTATTTCCAAGGCACCAAAAATAATTGTTCTTCACTTAAAAAGGTTTGACATCCAGGGTGCAGTAAAGAAGAAGCTGAGGACAGATATTCATTACCCACTGACCAACCTGGACCTCACTCCTTATATC
TGTCCAGTCTTCCGGAAACATCCCAAGTACAACCTGTGTGCAGTTGTGAACCACTTTGGAGATCTGGATGGTGGCCACTACACTGCCTTCTGCAAGAACTCAGTAACTCAGGCCTGGTATAGTTTTGA
CGACACCCGAGTCAGTGAGATTCCAGATACTTCTGTTCAAACAGCCACAGCTTATCTTTTATTCTATAGCTGCCAGCCTTTTTCTATCCCAACACAGAAGCGCAAGAGCTGGGACAGCACTCCTGATT
ACGGCAAGCCAGCCGTCAGGAAGTGGCCGTGAATATGCTTTGTTATTAAATCCTTCCCACCTACTCACATCGCTAAGGTTTGTACGTCTCACAGACAGCCTCTCTAAAACAAGTCTGC

hide sequence

RefSeq Acc Id:

XM_063284983 ⟹ XP_063141053

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	134,465,469 - 134,488,830 (-)	NCBI


Protein RefSeqs	NP_001417364	(Get FASTA)	NCBI Sequence Viewer
	NP_001417365	(Get FASTA)	NCBI Sequence Viewer
	XP_003749615	(Get FASTA)	NCBI Sequence Viewer
	XP_006235003	(Get FASTA)	NCBI Sequence Viewer
	XP_006235004	(Get FASTA)	NCBI Sequence Viewer
	XP_006235005	(Get FASTA)	NCBI Sequence Viewer
	XP_063141053	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL80092	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000015238
	ENSRNOP00000015238.6

RefSeq Acc Id:

XP_003749615 ⟸ XM_003749567

- Peptide Label:

isoform X1

- Sequence:

show sequence

MASHRPFPADDFGAYYILAECADYDSLPESETQPHFQGVTGLRNLGNTCYMNAILQCLCSTSPLVEYFLSGKYITALQKDCSEVTTAFAYLMTDMWLGDSDCVSPEIFLSAVGSLYPAFLKKTQQDAQ
EFLIYVLNELHEALKKHCRGRASEKRTAQNCCRKVPAHETSIITRLFEGQLSYSITCLKCETCTYKNEVFTILSLPIPSEYECSLQDCLQCFFQQDTLTWNNQIHCSFCEIKQETAVRTTISKAPKII
VLHLKRFDIQGAVKKKLRTDIHYPLTNLDLTPYICPVFRKHPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQAWYSFDDTRVSEIPDTSVQTATAYLLFYSCQPFSIPTQKRKSWDSTPDYGKPAVRKW
P

hide sequence

RefSeq Acc Id:

XP_006235004 ⟸ XM_006234942

- Peptide Label:

isoform X3

- Sequence:

show sequence

MNAILQCLCSTSPLVEYFLSGKYITALQKDCSEVTTAFAYLMTDMWLGDSDCVSPEIFLSAVGS
LYPAFLKKTQQDAQEFLIYVLNELHEALKKHCRGRASEKRTAQNCCRKVPAHETSIITRLFEGQLSYSITCLKCETCTYKNEVFTILSLPIPSEYECSLQDCLQCFFQQDTLTWNNQIHCSFCEIKQE
TAVRTTISKAPKIIVLHLKRFDIQGAVKKKLRTDIHYPLTNLDLTPYICPVFRKHPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQAWYSFDDTRVSEIPDTSVQTATAYLLFYSCQPFSIPTQKRKSW
DSTPDYGKPAVRKWP

hide sequence

RefSeq Acc Id:

XP_006235003 ⟸ XM_006234941

- Peptide Label:

isoform X3

- Sequence:

show sequence

MNAILQCLCSTSPLVEYFLSGKYITALQKDCSEVTTAFAYLMTDMWLGDSDCVSPEIFLSAVGS
LYPAFLKKTQQDAQEFLIYVLNELHEALKKHCRGRASEKRTAQNCCRKVPAHETSIITRLFEGQLSYSITCLKCETCTYKNEVFTILSLPIPSEYECSLQDCLQCFFQQDTLTWNNQIHCSFCEIKQE
TAVRTTISKAPKIIVLHLKRFDIQGAVKKKLRTDIHYPLTNLDLTPYICPVFRKHPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQAWYSFDDTRVSEIPDTSVQTATAYLLFYSCQPFSIPTQKRKSW
DSTPDYGKPAVRKWP

hide sequence

RefSeq Acc Id:

XP_006235005 ⟸ XM_006234943

- Peptide Label:

isoform X3

- Sequence:

show sequence

MNAILQCLCSTSPLVEYFLSGKYITALQKDCSEVTTAFAYLMTDMWLGDSDCVSPEIFLSAVGS
LYPAFLKKTQQDAQEFLIYVLNELHEALKKHCRGRASEKRTAQNCCRKVPAHETSIITRLFEGQLSYSITCLKCETCTYKNEVFTILSLPIPSEYECSLQDCLQCFFQQDTLTWNNQIHCSFCEIKQE
TAVRTTISKAPKIIVLHLKRFDIQGAVKKKLRTDIHYPLTNLDLTPYICPVFRKHPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQAWYSFDDTRVSEIPDTSVQTATAYLLFYSCQPFSIPTQKRKSW
DSTPDYGKPAVRKWP

hide sequence

Ensembl Acc Id:

ENSRNOP00000015238 ⟸ ENSRNOT00000015238

Protein Domains

USP

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LYZ4-F1-model_v2	AlphaFold	F1LYZ4	1-385	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13692396

Promoter ID:

EPDNEW_R2917

Type:

initiation region

Name:

Usp50_1

Description:

ubiquitin specific peptidase 50

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	119,247,395 - 119,247,455	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-48017	BioCyc
Ensembl Genes	ENSRNOG00000011401	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000015238	ENTREZGENE
	ENSRNOT00000015238.8	UniProtKB/TrEMBL
Gene3D-CATH	Cysteine proteinases	UniProtKB/TrEMBL
InterPro	Papain_like_cys_pep_sf	UniProtKB/TrEMBL
	Pept_C19ubi-hydrolase_C_CS	UniProtKB/TrEMBL
	Peptidase_C19	UniProtKB/TrEMBL
	Ub_carboxyl-term_hydrolase	UniProtKB/TrEMBL
	UCH/PAN2	UniProtKB/TrEMBL
KEGG Report	rno:311399	UniProtKB/TrEMBL
NCBI Gene	311399	ENTREZGENE
PANTHER	INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 50	UniProtKB/TrEMBL
	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE	UniProtKB/TrEMBL
Pfam	UCH	UniProtKB/TrEMBL
PhenoGen	Usp50	PhenoGen
PROSITE	UCH_2_1	UniProtKB/TrEMBL
	UCH_2_2	UniProtKB/TrEMBL
	UCH_2_3	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000011401	RatGTEx
Superfamily-SCOP	SSF54001	UniProtKB/TrEMBL
UniProt	F1LYZ4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Usp50	ubiquitin specific peptidase 50	RGD1564751_predicted	similar to RIKEN cDNA 4930511O11 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1564751_predicted	similar to RIKEN cDNA 4930511O11 (predicted)	LOC311399	similar to RIKEN cDNA 4930511O11	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC311399	similar to RIKEN cDNA 4930511O11			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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