Otud7a (OTU deubiquitinase 7A) - Rat Genome Database

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Gene: Otud7a (OTU deubiquitinase 7A) Rattus norvegicus
Analyze
Symbol: Otud7a
Name: OTU deubiquitinase 7A
RGD ID: 1563721
Description: Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and cysteine-type deubiquitinase activity. Predicted to be involved in protein K11-linked deubiquitination and protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm and nucleus. Orthologous to human OTUD7A (OTU deubiquitinase 7A); INTERACTS WITH acrylamide; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC309252; OTU domain containing 7A; OTU domain-containing protein 7A; RGD1563721; similar to Cezanne 2 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81126,476,275 - 126,800,037 (+)NCBIGRCr8
mRatBN7.21117,064,428 - 117,388,217 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1117,064,496 - 117,386,480 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01124,311,873 - 124,655,437 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,625,985 - 124,653,820 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01125,428,504 - 125,767,785 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41118,142,100 - 118,247,638 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1109,322,110 - 109,647,375 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Otud7aRatautism spectrum disorder  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:19050728 more ...
Otud7aRatautistic disorder  ISOOTUD7A (Homo sapiens)8554872ClinVar more ...ClinVarPMID:21681106 and PMID:30208311
Otud7aRatchromosome 15q11.2 deletion syndrome  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 15q11-q13 duplication syndromeClinVar 
Otud7aRatchromosome 15q13.3 microdeletion syndrome  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 15q13.3 microdeletion syndromeClinVarPMID:31690835
Otud7aRatcolorectal cancer  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Familial colorectal cancerClinVarPMID:22561515 more ...
Otud7aRatlanguage disorder  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Language disorderClinVarPMID:31997314
Otud7aRatlearning disability  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Specific learning disabilityClinVarPMID:31997314
Otud7aRatNEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND SEIZURES  ISOOTUD7A (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Otud7aRatNeurodevelopmental Disorders  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Otud7aRatnon-syndromic intellectual disability  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: Non-syndromic intellectual disabilityClinVarPMID:25741868
Otud7aRatschizophrenia  ISOOTUD7A (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311
1 to 11 of 11 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Otud7aRatchromosome 15q13.3 microdeletion syndrome  ISSOtud7a (Mus musculus)13592920OMIM:612001MouseDO 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Otud7aRatNEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND SEIZURES  ISOOTUD7A (Homo sapiens)7240710 OMIM 

1 to 20 of 34 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Otud7aRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOOtud7a (Mus musculus)6480464Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to OTUD7A promoter]CTDPMID:19654925
Otud7aRatacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of OTUD7A mRNACTDPMID:28959563
Otud7aRataflatoxin B1 affects methylationISOOTUD7A (Homo sapiens)6480464Aflatoxin B1 affects the methylation of OTUD7A intronCTDPMID:30157460
Otud7aRataflatoxin B1 decreases expressionISOOTUD7A (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of OTUD7A mRNACTDPMID:32234424
Otud7aRatAflatoxin B2 alpha increases methylationISOOTUD7A (Homo sapiens)6480464aflatoxin B2 results in increased methylation of OTUD7A intronCTDPMID:30157460
Otud7aRatall-trans-retinoic acid decreases expressionISOOTUD7A (Homo sapiens)6480464Tretinoin results in decreased expression of OTUD7A mRNACTDPMID:33167477
Otud7aRatatrazine affects methylationEXP 6480464Atrazine affects the methylation of OTUD7A geneCTDPMID:35440735
Otud7aRatbenzo[a]pyrene affects methylationISOOTUD7A (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of OTUD7A intronCTDPMID:30157460
Otud7aRatbenzo[e]pyrene increases methylationISOOTUD7A (Homo sapiens)6480464benzo(e)pyrene results in increased methylation of OTUD7A intronCTDPMID:30157460
Otud7aRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of OTUD7A mRNACTDPMID:25181051 more ...
Otud7aRatbisphenol A multiple interactionsISOOTUD7A (Homo sapiens)6480464[bisphenol A co-treated with Fulvestrant] results in increased methylation of OTUD7A geneCTDPMID:31601247
Otud7aRatbisphenol A decreases methylationISOOTUD7A (Homo sapiens)6480464bisphenol A results in decreased methylation of OTUD7A geneCTDPMID:31601247
Otud7aRatbisphenol A increases expressionISOOTUD7A (Homo sapiens)6480464bisphenol A results in increased expression of OTUD7A mRNACTDPMID:32028606
Otud7aRatCGP 52608 multiple interactionsISOOTUD7A (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to OTUD7A gene]CTDPMID:28238834
Otud7aRatDDE decreases expressionISOOTUD7A (Homo sapiens)6480464Dichlorodiphenyl Dichloroethylene results in decreased expression of OTUD7A mRNACTDPMID:38568856
Otud7aRatDibutyl phosphate affects expressionISOOTUD7A (Homo sapiens)6480464di-n-butylphosphoric acid affects the expression of OTUD7A mRNACTDPMID:37042841
Otud7aRatfulvestrant multiple interactionsISOOTUD7A (Homo sapiens)6480464[bisphenol A co-treated with Fulvestrant] results in increased methylation of OTUD7A geneCTDPMID:31601247
Otud7aRatgenistein increases expressionISOOtud7a (Mus musculus)6480464Genistein results in increased expression of OTUD7A mRNACTDPMID:32186404
Otud7aRatgentamycin decreases expressionEXP 6480464Gentamicins results in decreased expression of OTUD7A mRNACTDPMID:22061828
Otud7aRatglyphosate affects methylationEXP 6480464Glyphosate affects the methylation of OTUD7A geneCTDPMID:35440735

1 to 20 of 34 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Otud7aRatprotein deubiquitination involved_inIEAARBA:ARBA000278791600115GO_REF:0000117UniProtGO_REF:0000117
Otud7aRatprotein deubiquitination involved in ubiquitin-dependent protein catabolic process involved_inIBAPANTHER:PTN001001090 and UniProtKB:Q9UGI01600115GO_REF:0000033GO_CentralGO_REF:0000033
Otud7aRatprotein K11-linked deubiquitination involved_inISOOTUD7A (Homo sapiens)1624291 PMID:23827681RGDPMID:23827681

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Otud7aRatcytoplasm is_active_inIBAMGI:1196377 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Otud7aRatcytoplasm located_inIEAARBA:ARBA000269711600115GO_REF:0000117UniProtGO_REF:0000117
Otud7aRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Otud7aRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Otud7aRatnucleus is_active_inIBAPANTHER:PTN001001090 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Otud7aRatnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Otud7aRatnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Otud7aRatcysteine-type deubiquitinase activity enablesISOOTUD7A (Homo sapiens)1624291 PMID:23827681RGDPMID:23827681
Otud7aRatcysteine-type deubiquitinase activity enablesIBAMGI:2654703 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Otud7aRatcysteine-type deubiquitinase activity enablesIEAEC:3.4.19.121600115GO_REF:0000003UniProtGO_REF:0000003
Otud7aRatcysteine-type peptidase activity enablesIEAUniProtKB-KW:KW-07881600115GO_REF:0000043UniProtGO_REF:0000043
Otud7aRatDNA binding enablesIEAInterPro:IPR0026531600115GO_REF:0000002InterProGO_REF:0000002
Otud7aRathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Otud7aRatK63-linked polyubiquitin modification-dependent protein binding enablesIBAMGI:2654703 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Otud7aRatmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Otud7aRatzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
Otud7aRatzinc ion binding enablesIEAInterPro:IPR0026531600115GO_REF:0000002InterProGO_REF:0000002
1 to 10 of 10 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:23827681  



Otud7a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81126,476,275 - 126,800,037 (+)NCBIGRCr8
mRatBN7.21117,064,428 - 117,388,217 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1117,064,496 - 117,386,480 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01124,311,873 - 124,655,437 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,625,985 - 124,653,820 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01125,428,504 - 125,767,785 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41118,142,100 - 118,247,638 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1109,322,110 - 109,647,375 (+)NCBICelera
Cytogenetic Map1q22NCBI
OTUD7A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381531,475,398 - 31,870,673 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1531,475,398 - 31,870,789 (-)EnsemblGRCh38hg38GRCh38
GRCh371531,767,601 - 32,162,876 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361529,562,621 - 29,734,834 (-)NCBINCBI36Build 36hg18NCBI36
Build 341529,562,620 - 29,734,834NCBI
Celera159,500,530 - 9,586,701 (-)NCBICelera
Cytogenetic Map15q13.3NCBI
HuRef158,953,038 - 9,124,721 (-)NCBIHuRef
CHM1_11531,766,251 - 31,937,781 (-)NCBICHM1_1
T2T-CHM13v2.01529,269,748 - 29,664,824 (-)NCBIT2T-CHM13v2.0
Otud7a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39763,094,493 - 63,415,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl763,094,499 - 63,408,776 (+)EnsemblGRCm39 Ensembl
GRCm38763,444,745 - 63,766,232 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl763,444,751 - 63,759,028 (+)EnsemblGRCm38mm10GRCm38
MGSCv37770,589,658 - 70,903,913 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36763,323,722 - 63,637,977 (+)NCBIMGSCv36mm8
Celera760,886,403 - 61,203,588 (+)NCBICelera
Cytogenetic Map7CNCBI
cM Map734.52NCBI
Otud7a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541630,244,875 - 30,427,829 (-)NCBIChiLan1.0ChiLan1.0
OTUD7A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21620,288,790 - 20,677,159 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11525,006,920 - 25,401,235 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0159,974,737 - 10,360,991 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11529,014,295 - 29,217,332 (-)NCBIpanpan1.1PanPan1.1panPan2
OTUD7A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1337,348,167 - 37,548,357 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl337,348,170 - 37,548,885 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha339,829,134 - 40,221,120 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0337,535,390 - 37,922,120 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl337,535,447 - 37,921,786 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1337,068,759 - 37,455,071 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0337,323,919 - 37,708,706 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0337,531,469 - 37,918,419 (+)NCBIUU_Cfam_GSD_1.0
Otud7a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640145,895,615 - 146,220,872 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936483302,953 - 430,825 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936483113,611 - 432,439 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTUD7A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1143,280,174 - 143,419,237 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11143,109,177 - 143,426,305 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21159,252,983 - 159,368,473 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OTUD7A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12650,842,957 - 51,213,515 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604889,610,045 - 89,983,865 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Otud7a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247681,348,377 - 1,482,158 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247681,326,417 - 1,482,474 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Otud7a
2049 total Variants

Predicted Target Of
Summary Value
Count of predictions:124
Count of miRNA genes:99
Interacting mature miRNAs:105
Transcripts:ENSRNOT00000021068
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 55 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1103111621148111621Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
631569Bp93Blood pressure QTL 930.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1106047847121834139Rat

1 to 10 of 55 rows
D1Mco44  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81126,659,981 - 126,660,146 (+)Marker Load Pipeline
mRatBN7.21117,248,161 - 117,248,326 (+)MAPPERmRatBN7.2
Rnor_6.01124,509,796 - 124,509,960NCBIRnor6.0
Rnor_5.01125,622,258 - 125,622,422UniSTSRnor5.0
RGSC_v3.41118,108,365 - 118,108,530RGDRGSC3.4
RGSC_v3.41118,108,366 - 118,108,530UniSTSRGSC3.4
RGSC_v3.1X89,536,733 - 89,536,754RGD
Celera1109,505,335 - 109,505,497UniSTS
Cytogenetic Map1q22UniSTS
AW556797  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27133,411,176 - 133,411,309 (+)MAPPERmRatBN7.2
mRatBN7.21117,328,176 - 117,328,304 (+)MAPPERmRatBN7.2
Rnor_6.01124,589,813 - 124,589,940NCBIRnor6.0
Rnor_6.07143,884,081 - 143,884,213NCBIRnor6.0
Rnor_5.07141,680,987 - 141,681,119UniSTSRnor5.0
Rnor_5.01125,702,275 - 125,702,402UniSTSRnor5.0
RGSC_v3.41118,188,383 - 118,188,510UniSTSRGSC3.4
RGSC_v3.47141,035,009 - 141,035,141UniSTSRGSC3.4
Celera7129,844,608 - 129,844,740UniSTS
Celera1109,585,321 - 109,585,448UniSTS
Cytogenetic Map7q36UniSTS
Cytogenetic Map1q22UniSTS
BE102181  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21117,206,738 - 117,206,900 (+)MAPPERmRatBN7.2
Rnor_6.01124,461,700 - 124,461,861NCBIRnor6.0
Rnor_5.01125,574,394 - 125,574,555UniSTSRnor5.0
RGSC_v3.41118,065,788 - 118,065,949UniSTSRGSC3.4
Celera1109,463,847 - 109,464,008UniSTS
RH 3.4 Map21658.81UniSTS
Cytogenetic Map1q22UniSTS
BF390890  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21117,075,986 - 117,076,138 (+)MAPPERmRatBN7.2
Rnor_6.01124,323,413 - 124,323,564NCBIRnor6.0
Rnor_5.01125,440,044 - 125,440,195UniSTSRnor5.0
RGSC_v3.41117,933,632 - 117,933,783UniSTSRGSC3.4
Celera1109,333,533 - 109,333,684UniSTS
Cytogenetic Map1q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 11 43 113 57 56 25 24 25 6 167 90 93 36 60 31



Ensembl Acc Id: ENSRNOT00000021068   ⟹   ENSRNOP00000021068
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1117,064,496 - 117,386,480 (+)Ensembl
Rnor_6.0 Ensembl1124,625,985 - 124,653,820 (+)Ensembl
RefSeq Acc Id: XM_008759566   ⟹   XP_008757788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81126,476,275 - 126,800,037 (+)NCBI
mRatBN7.21117,064,428 - 117,388,217 (+)NCBI
Rnor_6.01124,311,873 - 124,655,437 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008759568   ⟹   XP_008757790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81126,476,275 - 126,800,037 (+)NCBI
mRatBN7.21117,064,428 - 117,388,217 (+)NCBI
Rnor_6.01124,311,873 - 124,655,437 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063278750   ⟹   XP_063134820
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81126,476,275 - 126,800,037 (+)NCBI
RefSeq Acc Id: XM_063278751   ⟹   XP_063134821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81126,538,387 - 126,800,037 (+)NCBI
RefSeq Acc Id: XM_063278757   ⟹   XP_063134827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81126,692,611 - 126,800,037 (+)NCBI
RefSeq Acc Id: XM_063278759   ⟹   XP_063134829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81126,476,275 - 126,800,037 (+)NCBI
1 to 9 of 9 rows
Protein RefSeqs XP_008757788 (Get FASTA)   NCBI Sequence Viewer  
  XP_008757790 (Get FASTA)   NCBI Sequence Viewer  
  XP_063134820 (Get FASTA)   NCBI Sequence Viewer  
  XP_063134821 (Get FASTA)   NCBI Sequence Viewer  
  XP_063134827 (Get FASTA)   NCBI Sequence Viewer  
  XP_063134829 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM08376 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021068.6
  ENSRNOP00000110596
1 to 9 of 9 rows
RefSeq Acc Id: XP_008757788   ⟸   XM_008759566
- Peptide Label: isoform X3
- UniProtKB: D4ABZ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008757790   ⟸   XM_008759568
- Peptide Label: isoform X4
- UniProtKB: D4ABZ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021068   ⟸   ENSRNOT00000021068
RefSeq Acc Id: XP_063134820   ⟸   XM_063278750
- Peptide Label: isoform X1
- UniProtKB: D4ABZ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134829   ⟸   XM_063278759
- Peptide Label: isoform X2
- UniProtKB: D4ABZ4 (UniProtKB/TrEMBL)
A20-type   OTU

Name Modeler Protein Id AA Range Protein Structure
AF-D4ABZ4-F1-model_v2 AlphaFold D4ABZ4 1-745 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 22 of 22 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-59091 BioCyc
Ensembl Genes ENSRNOG00000015503 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021068.7 UniProtKB/TrEMBL
  ENSRNOT00000139392 ENTREZGENE
Gene3D-CATH 1.20.5.4770 UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
InterPro OTU_Deubiquitinase UniProtKB/TrEMBL
  OTU_dom UniProtKB/TrEMBL
  UBA_8 UniProtKB/TrEMBL
  Znf_A20 UniProtKB/TrEMBL
NCBI Gene 309252 ENTREZGENE
PANTHER PTHR13367:SF9 UniProtKB/TrEMBL
  UBIQUITIN THIOESTERASE UniProtKB/TrEMBL
Pfam OTU UniProtKB/TrEMBL
  UBA_8 UniProtKB/TrEMBL
  zf-A20 UniProtKB/TrEMBL
PhenoGen Otud7a PhenoGen
PROSITE OTU UniProtKB/TrEMBL
  ZF_A20 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015503 RatGTEx
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt D4ABZ4 ENTREZGENE, UniProtKB/TrEMBL
1 to 22 of 22 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-13 Otud7a  OTU deubiquitinase 7A  Otud7a  OTU domain containing 7A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Otud7a  OTU domain containing 7A  RGD1563721_predicted  similar to Cezanne 2 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563721_predicted  similar to Cezanne 2 protein (predicted)  LOC309252  similar to Cezanne 2 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC309252  similar to Cezanne 2 protein      Symbol and Name status set to provisional 70820 PROVISIONAL