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Gene: Usp26 (ubiquitin specific peptidase 26) Rattus norvegicus

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Symbol:

Usp26

Name:

ubiquitin specific peptidase 26

RGD ID:

1563443

Description:

Predicted to enable K48-linked deubiquitinase activity and cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including G1/S transition of mitotic cell cycle; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; and regulation of androgen receptor signaling pathway. Predicted to be located in nucleoplasm and sperm flagellum. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 6. Orthologous to human USP26 (ubiquitin specific peptidase 26); INTERACTS WITH bisphenol A; 2,3',4,4',5-Pentachlorobiphenyl (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC108353303; LOC302488; RGD1563443; similar to ubiquitin specific protease; ubiquitin carboxyl-terminal hydrolase 26; uncharacterized LOC108353303

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	USP26 (ubiquitin specific peptidase 26)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Usp26 (ubiquitin specific peptidase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Usp26 (ubiquitin specific peptidase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	USP26 (ubiquitin specific peptidase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	USP26 (ubiquitin specific peptidase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Usp26 (ubiquitin specific peptidase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	USP26 (ubiquitin specific peptidase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	USP26 (ubiquitin specific peptidase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Usp26 (ubiquitin specific peptidase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	USP29 (ubiquitin specific peptidase 29)	HGNC	OrthoDB, Panther
Alliance orthologs ³
Homo sapiens (human):	USP26 (ubiquitin specific peptidase 26)	Alliance	DIOPT (HGNC\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Usp26 (ubiquitin specific peptidase 26)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C04E6.5	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Caenorhabditis elegans (roundworm):	duo-3	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Saccharomyces cerevisiae (baker's yeast):	UBP7	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	UBP11	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	136,237,504 - 136,284,646 (-)	NCBI		GRCr8
mRatBN7.2	X	131,317,200 - 131,363,964 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	131,319,194 - 131,363,970 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	133,476,889 - 133,520,935 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	137,058,822 - 137,102,868 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	134,633,247 - 134,677,367 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	139,030,239 - 139,079,336 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	139,030,804 - 139,079,336 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	139,084,571 - 139,131,158 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	138,625,478 - 138,669,690 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	130,238,525 - 130,282,649 (-)	NCBI		Celera
Cytogenetic Map	X	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp26	Rat	Asthenozoospermia		ISO	USP26 (Homo sapiens)	8554872	ClinVar Annotator: match by term: asthenozoospermia	ClinVar	PMID:25741868 more ...
Usp26	Rat	autistic disorder		ISO	USP26 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Autism	ClinVar	PMID:21681106 and PMID:30208311
Usp26	Rat	autosomal hemophilia A		ISO	USP26 (Homo sapiens)	8554872	ClinVar Annotator: match by term: AUTOSOMAL HEMOPHILIA A	ClinVar	PMID:31690835
Usp26	Rat	factor VIII deficiency		ISO	USP26 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Factor 8 deficiency and congenital	ClinVar	PMID:31690835
Usp26	Rat	male infertility		ISO	USP26 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Male infertility	ClinVar
Usp26	Rat	oligospermia		ISO	USP26 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Oligospermia	ClinVar	PMID:25741868 more ...
Usp26	Rat	syndromic X-linked intellectual disability Lubs type		ISO	USP26 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs type	ClinVar	PMID:25741868
Usp26	Rat	Teratozoospermia		ISO	USP26 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Teratozoospermia	ClinVar	PMID:25741868 more ...
Usp26	Rat	X-linked spermatogenic failure 6		ISO	USP26 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:25741868 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp26	Rat	X-linked spermatogenic failure 6		ISO	USP26 (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp26	Rat	2,3',4,4',5-Pentachlorobiphenyl	increases expression	ISO	Usp26 (Mus musculus)	6480464	2 more ...	CTD	PMID:31388691
Usp26	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Usp26 (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of USP26 mRNA	CTD	PMID:21570461
Usp26	Rat	benzo[a]pyrene	affects methylation	ISO	USP26 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of USP26 exon	CTD	PMID:27901495
Usp26	Rat	bis(2-ethylhexyl) phthalate	increases methylation	ISO	Usp26 (Mus musculus)	6480464	Diethylhexyl Phthalate results in increased methylation of USP26 gene	CTD	PMID:34319233
Usp26	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of USP26 mRNA	CTD	PMID:25181051
Usp26	Rat	cadmium dichloride	increases expression	ISO	Usp26 (Mus musculus)	6480464	Cadmium Chloride results in increased expression of USP26 mRNA	CTD	PMID:20061341
Usp26	Rat	CGP 52608	multiple interactions	ISO	USP26 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to USP26 gene]	CTD	PMID:28238834
Usp26	Rat	sodium arsenite	increases expression	ISO	USP26 (Homo sapiens)	6480464	sodium arsenite results in increased expression of USP26 mRNA	CTD	PMID:38568856
Usp26	Rat	sodium arsenite	decreases expression	ISO	USP26 (Homo sapiens)	6480464	sodium arsenite results in decreased expression of USP26 mRNA	CTD	PMID:34032870

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp26	Rat	G1/S transition of mitotic cell cycle	involved_in	IBA	PANTHER:PTN002363418 and UniProtKB:Q86T82	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp26	Rat	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	involved_in	ISO	USP26 (Homo sapiens)	1624291	PMID:28839133	RGD	PMID:28839133
Usp26	Rat	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	involved_in	ISO	Usp26 (Mus musculus)	1624291	PMID:28839133	RGD	PMID:28839133
Usp26	Rat	protein deubiquitination	involved_in	IEA	InterPro:IPR001394	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Usp26	Rat	proteolysis	involved_in	IEA	UniProtKB-KW:KW-0645	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp26	Rat	regulation of androgen receptor signaling pathway	involved_in	ISO	USP26 (Homo sapiens)	1624291	PMID:20501646	RGD	PMID:20501646
Usp26	Rat	regulation of protein stability	involved_in	IBA	FB:FBgn0016756 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp26	Rat	spermatogenesis	involved_in	ISO	USP26 (Homo sapiens)	1624291	PMID:34202084	RGD	PMID:34202084

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp26	Rat	cytosol	located_in	ISO	USP26 (Homo sapiens)	1624291		RGD	GO_REF:0000052
Usp26	Rat	cytosol	is_active_in	IBA	FB:FBgn0016756 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp26	Rat	nucleoplasm	located_in	ISO	USP26 (Homo sapiens)	1624291		RGD	GO_REF:0000052
Usp26	Rat	nucleus	located_in	ISO	USP26 (Homo sapiens)	1624291	PMID:20501646	RGD	PMID:20501646
Usp26	Rat	nucleus	is_active_in	IBA	FB:FBgn0016756 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp26	Rat	sperm flagellum	located_in	ISO	USP26 (Homo sapiens)	1624291	PMID:34202084	RGD	PMID:34202084

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp26	Rat	cysteine-type deubiquitinase activity	enables	IEA	EC:3.4.19.12	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Usp26	Rat	cysteine-type deubiquitinase activity	enables	IEA	InterPro:IPR001394 and InterPro:IPR018200	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Usp26	Rat	cysteine-type deubiquitinase activity	enables	IEA	UniRule:UR000880756	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Usp26	Rat	cysteine-type deubiquitinase activity	enables	IBA	FB:FBgn0005632 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp26	Rat	cysteine-type peptidase activity	enables	IEA	UniProtKB-KW:KW-0788	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp26	Rat	deubiquitinase activity	enables	ISO	USP26 (Homo sapiens)	1624291	PMID:20501646	RGD	PMID:20501646
Usp26	Rat	hydrolase activity	enables	IEA	UniProtKB-KW:KW-0378	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp26	Rat	K48-linked deubiquitinase activity	enables	ISO	USP26 (Homo sapiens)	1624291	PMID:28839133	RGD	PMID:28839133
Usp26	Rat	peptidase activity	enables	IEA	UniProtKB-KW:KW-0645	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp26	Rat	protein binding	enables	ISO	USP26 (Homo sapiens)	1624291	UniProtKB:O00257 more ...	RGD	PMID:20501646 more ...

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:20501646

Usp26
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	136,237,504 - 136,284,646 (-)	NCBI		GRCr8
mRatBN7.2	X	131,317,200 - 131,363,964 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	131,319,194 - 131,363,970 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	133,476,889 - 133,520,935 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	137,058,822 - 137,102,868 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	134,633,247 - 134,677,367 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	139,030,239 - 139,079,336 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	139,030,804 - 139,079,336 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	139,084,571 - 139,131,158 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	138,625,478 - 138,669,690 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	130,238,525 - 130,282,649 (-)	NCBI		Celera
Cytogenetic Map	X	q36	NCBI

USP26
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	133,023,168 - 133,097,109 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	133,023,168 - 133,097,109 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	132,157,196 - 132,231,137 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	131,987,173 - 131,989,966 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	131,885,026 - 131,887,820	NCBI
Celera	X	132,545,874 - 132,548,667 (-)	NCBI		Celera
Cytogenetic Map	X	q26.2	NCBI
HuRef	X	121,562,395 - 121,565,188 (-)	NCBI		HuRef
CHM1_1	X	132,071,082 - 132,073,875 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	131,347,885 - 131,421,825 (-)	NCBI		T2T-CHM13v2.0

Usp26
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	50,841,544 - 50,890,110 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	50,842,836 - 50,890,110 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	51,752,667 - 51,801,233 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	51,753,959 - 51,801,233 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	49,107,136 - 49,154,410 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	47,998,586 - 48,042,380 (-)	NCBI		MGSCv36	mm8
Celera	X	39,175,908 - 39,222,874 (-)	NCBI		Celera
Cytogenetic Map	X	A5	NCBI
cM Map	X	28.31	NCBI

Usp26
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955473	1,903,865 - 1,957,747 (+)	NCBI	ChiLan1.0	ChiLan1.0

USP26
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	132,433,181 - 132,493,776 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	132,436,775 - 132,497,371 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	122,155,933 - 122,160,000 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	132,463,139 - 132,465,933 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	132,463,140 - 132,465,887 (-)	Ensembl	panpan1.1		panPan2

USP26
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	103,869,903 - 103,930,495 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	103,872,397 - 103,875,171 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	90,042,316 - 90,060,916 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	105,726,832 - 105,789,778 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	105,729,326 - 105,732,100 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	103,140,338 - 103,203,243 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	105,015,482 - 105,072,425 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	104,789,168 - 104,852,070 (-)	NCBI		UU_Cfam_GSD_1.0

Usp26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	102,040,698 - 102,044,002 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936691	1,913,416 - 1,916,214 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

USP26
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	X	109,092,622 - 109,095,548 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	125,124,840 - 125,177,383 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

USP26
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	108,187,526 - 108,275,829 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	108,187,858 - 108,190,605 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	45,699,469 - 45,702,346 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Usp26
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624797	12,724,584 - 12,797,308 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Usp26
185 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	426
Count of miRNA genes:	239
Interacting mature miRNAs:	291
Transcripts:	ENSRNOT00000047605
Prediction methods:	Microtar, Miranda, Pita, Pita,Microtar, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	93956491	138956491	Rat
1598856	Memor1	Memory QTL 1	1.9		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	X	103312877	148312877	Rat
1598809	Memor15	Memory QTL 15	4.4		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	103312877	148312877	Rat
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	100567703	150256146	Rat
634346	Insul4	Insulin level QTL 4	0		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	X	126975089	152453651	Rat
738029	Stresp2	Stress response QTL 2	3.4	0.0004	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	112934952	138400867	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	113937816	152453651	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
6	3	10	33	37	31	17	9	17	6	101	34	18	41	56	14


RefSeq Transcripts	NM_001106948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001433989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008773555	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099603	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000047605 ⟹ ENSRNOP00000047375

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	131,319,717 - 131,363,846 (-)	Ensembl
Rnor_6.0 Ensembl	X	139,030,804 - 139,079,336 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116818 ⟹ ENSRNOP00000085992

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	131,319,194 - 131,363,970 (-)	Ensembl

RefSeq Acc Id:

NM_001106948 ⟹ NP_001100418

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	136,240,379 - 136,284,507 (-)	NCBI
mRatBN7.2	X	131,319,717 - 131,363,846 (-)	NCBI
Rnor_6.0	X	139,030,804 - 139,079,336 (-)	NCBI
Rnor_5.0	X	139,084,571 - 139,131,158 (-)	NCBI
RGSC_v3.4	X	138,625,478 - 138,669,690 (-)	RGD
Celera	X	130,238,525 - 130,282,649 (-)	RGD

Sequence:

show sequence

CCACAACCAATCTAGGTCCGTGGAGGTGGTACCATAAACTGCCTATAAAAGGAGGCTCACAGGGTGCTCGGCCTCCATTTTGTCTCAGCTTTCGGGGTGTGCTGTGGTAGATTCTCTGTGCTCCAGAA
AGCTAAGGGGCTGGTTAGTTCTCGAAACAAACAGGACAGCACGGTGACAAAAAGGAGTGTGGGCTCGACCAGTGCAGACCGGACCAGACCGGACCAGACCGGACCAGACCAGACCAGACCGGATCGCA
GCTTAGACTGGGTGCACTAGCGTTCTTCTGAGAAAGAGCACCAGTGTCCAAGCCAGGTAGTGCTTGACTACCTACTCACAGAAAATCTCATCGACAGTGGAAGAATTGCCTGAAGTGGATTGTAAAAA
CAGAACTGCAAGAGTCAAGAGAGTGTTGGAGGGAGTGTTCAGGCCAGAGTCTCTGTTCCATACAGCAGCAAATCCTAAGGCTTGAGTGATCTCCATTCACTGTTTCCAGCTGTGCTGAGTGCCTGTCT
TAAGATTCTGATAAAGGTTGTTCTCCCTTGGCATACATTGCTGAGTTGGAAAACTGCTTCACTTGCATTTAGCGTTCAGCGTCATTTTCTGGTGAACTTAGGAAACAAACTAAACCGTCAAGATTGCT
AGTAACCAAGAAACGTGTGTTTATTTGCCAAGAAAAAAAAGTATGGATCCTGTATTGATACATGCTCAAGTCCAGCTGTGGAGTGCAAAGGCAGGAATGTCCAAGTCAAGAAATGCATTCATTGAGAC
ATTTATAGGCAAAAGGGAAGTTAAACTTATTCTCTATTTCAGCACTGGAAAGATCAAGGCTTTGCAACTATACAATAATATTAAAAGTGTGGTCCTTCGAACCTATGGCGAAGACCAGAATTACCTAC
ATCTGACTTTTAAAAATAATGATTTCTTGTTTGTCGAGAAACTCACCACCATGGATGCCAGACGACTGAAAAGATTTTTGGACAAAATCTATCAAAGTAATCTTCGGGCAGCCAGGAGAAGTGGTGAG
AGACCTGGTGATCCTAGCACGAGTGCACAGGAGTTGAGCTCTTCCCCACCGGAAGGTCATCTGAAAGCAAGTAGTGCGTGCTTTGAATCAGCCAAAGAAAGCGAAATGTGCTTGTTTCGTCAGTTGCC
TTTACTTCCGCCCTCATCAGCCTCACTTAATGCAGTAGGATTATTAGAATCACAGTTCATGAAGAGGAAAAGATTTTTTCTTGGTGCAGAAAAGGAAAAACAGAACCTGAAGGGCAGTACCAGAGAAT
TTGAGACAAATTTAGTAGTGTCCATATCTAATGAAAAGGGGAAAGAAAGGGGTGTGAGAGCGGTAGAAATCAGTAAGGCAGGGTTTGGATTTCCATTTGAGACCAACTATCCCGAGGAGGGTAGTGTG
AATGTTCGTGATCTTAATGATCTCATTACAAAATTATTTTCACCATTACTGTTTGAAACGCACTATATTGAGAATGGGCTAGATTGGCATGAGTATATGGAGACATTTTTACTTGACCCAGAAAAGTC
ATGGCAAGGCCTACCTAATGTTGGAAATACCTGTTACATAAATGTTGTATTACAGTCTCTATGCTCAATTCCGCTGTTTGTTAATGACTTATTCAATCAGGGCTTCCCATGGATTAAACCTCCCAAAG
ATGACTTTAACATGCGCTTGATGCAACTGCTGGTTTTGAAAGATATTTACAATGCAAGAACCAGACAAAAGTTACTTATAGGTATTACAAAAGCCCTCCCAATATTTGGCGAGGTCTTTGCAGCTGAC
AGGCAGAATGATGCTCATGAATTTTTGAGTCTCTGTTTAGTTCAGTTGAAGGAGACTGTCCAGAGAGTAAACATGATGTGGCAATCTGAGAATGAATCAGGAGATTATTATTTACTTAGAGAGATTTT
TGCTAATTATACTAGCATCAACAGAACACCTGTTTGTCCTGTTACCAACAATTTTGAATTTGAGTTGCTGAGTTCCATCTTTTGTAAAGCCTGTGGCCTGACTGTTTTTAAGAGAGAACCAAGTAGAT
ATCTCTCTATCAACATTCCTCAAGGAATGAAAGACCAAAACATGTCTATCCAGTCCAGTTTAGATCTTTTCTTTAGGGCAGAGGAGCTTGAGCATAGGTGTGAAAGGTGTTTGTACAATAAATCTGTT
GCATTGCACAAGTTTGGCCGGCTACCCAGGGTTATTATTGTTCACCTGAAACGCTACAGCTTTAGTGAGTCCCGGATAATGAACAAAGATGAGCAGCACATTGTTATTTCCAAGTACTTACGGCTGTC
TTGTCACTGCAACAAGAACACAAAACCTCCCCAGCCCCTTCTCCCAAATGAGCATGTTAAGAATCTTGACTTACTAAGACCCCTTGAAGAGTTGGGTTCAGAAATACTCAAATTATCAAGTAATTCAG
GGAGGACCTCAAGATCCAAGGTTTTCCCGACTGTAAACATCAGATCAGACAAGGAGTTAGAAGTACAAAATGGAAAGAGAGTCTCTGAAGTGTCGAGTGGGTCAGCGCAGCAGGAAGATCCAGGGAAA
GGTGCAAATGTGGTCAGGTCAGAACTTACAAATGAGACTGAGACAATCAAACACGAGAAAGAGTATGTACTTAGTGATTTAGATTCTGGTAGCATCAGTGAGGAGCGATCACAAAAGTGCCAAGAGGC
TGAGAAATGCAATAAAGAGGCACTTCCTCAAAGCTGTCCAAAACCCAGCTCCCAGGAACAGACAGAAAACCTTGGGAAACCTGCAGTGTCACATACCCAGAATGGTAGTCTAAGTTCACAGGGCTCAT
CAGATTCCAGTAAGAGCCCTGGATGCAATGATGTTTTCGATAAGGCAAAGCCTACAAGCAAGGTGGAGCCACAGAAGTTAAATCAAAAAGAAGATAACATTTACAGGCTTGTTAGTATTATCAACCAT
ATTGGGAACAGTCCCAATGGAGGCCACTATATCAATGATGCCTTTGACTTCAGGAAGCAGAGTTGGTTCACTTATAGTGATCTACAGGTGACAGGTATACAAGAGGACCTTGTATATAAGGCTAGGCT
TTCTACTGGATATGTCTTCTTTTACATGCATAATGATATCTTTGAAGAGCTCTTGGCAAAGGAAGCTTGGTCTACTAGCACGTCCAAGGGTTAGTAAGAACAGCATATGCCTCACAGAACATGTCTAC
CCAAATGCCTCACTTAACCTAAAAATAATTAGCCCAGGACCAACACCTTAATAAACATTTAGAGAGAAAGTTCCTTTTCGACTGTGACCACATCAGTCTTATCACTACAGCTCATGCTAATGAGTGTT
CTTCTCTCATACAAATTTGGAACTGTACCTTTTGTATAACTTTGTCAGAAAATTTATTACTGACAGTGAGATTTTCAATATTTGCTCTGGAAGTTATATAACCCAAAATTGCCATTCTATTGATTAAA
ATGGCTTATTTGCACTCAAAAACATTCCAGTAAAAGGTACATTTTCTCTCTGCCTTTCTTGGAGGGTCAGCTTAAGAAGTTATAATGAAAAAGCTTTTACATAACAGAACCAAAAAAGCACATGCCCA
GACACACCACAGTTCAGATGAGTCTACCCAGCACTGTTACCCTAGCCTGCTGCTCTCTTGTTATCTCTCCATTAGAAATGGTTTAGTGTCCTAATTCTCTCCTGGCTTTCTCACAGTGGATATCATTT
AATGGTGGAGCTGAAGTGAGGAGAGAGGAGAACATTTTTTGGCTTCACATATTGGGAAAATATTCAAAAAGGTGGGGAGGGACACATTTCCCTTTTTTCATTTTTGAGGGTTTTCGTTATCACTGAAC
AGTGTTCTTACTGAACCCAGGCTTCAGTTATGATACTGTTGAGTCCACTTTCTAGTGTCTGTCTTTAGTTGTCTTTAATTGGGTTATTTTCTTAATAGAAAAAATTCTACCTCTGGAATTAATGTTGA
AGGAGCTTTGCGTGTTCTCAGGGGTGACGATATCCTCTTGGAATGCTCTATTTGGGATGGTTGACACAGT

hide sequence

RefSeq Acc Id:

XM_039099603 ⟹ XP_038955531

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	136,237,504 - 136,284,646 (-)	NCBI
mRatBN7.2	X	131,317,200 - 131,363,964 (-)	NCBI

RefSeq Acc Id:

XM_039099605 ⟹ XP_038955533

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	136,237,504 - 136,284,625 (-)	NCBI
mRatBN7.2	X	131,317,200 - 131,363,964 (-)	NCBI


Protein RefSeqs	NP_001100418	(Get FASTA)	NCBI Sequence Viewer
	NP_001420918	(Get FASTA)	NCBI Sequence Viewer
	XP_038955531	(Get FASTA)	NCBI Sequence Viewer
	XP_038955533	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM10949	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000047375
	ENSRNOP00000047375.3
	ENSRNOP00000085992
	ENSRNOP00000085992.1

RefSeq Acc Id:

NP_001100418 ⟸ NM_001106948

- UniProtKB:

D4A5S1 (UniProtKB/TrEMBL), A6JMT7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDPVLIHAQVQLWSAKAGMSKSRNAFIETFIGKREVKLILYFSTGKIKALQLYNNIKSVVLRTYGEDQNYLHLTFKNNDFLFVEKLTTMDARRLKRFLDKIYQSNLRAARRSGERPGDPSTSAQELSS
SPPEGHLKASSACFESAKESEMCLFRQLPLLPPSSASLNAVGLLESQFMKRKRFFLGAEKEKQNLKGSTREFETNLVVSISNEKGKERGVRAVEISKAGFGFPFETNYPEEGSVNVRDLNDLITKLFS
PLLFETHYIENGLDWHEYMETFLLDPEKSWQGLPNVGNTCYINVVLQSLCSIPLFVNDLFNQGFPWIKPPKDDFNMRLMQLLVLKDIYNARTRQKLLIGITKALPIFGEVFAADRQNDAHEFLSLCLV
QLKETVQRVNMMWQSENESGDYYLLREIFANYTSINRTPVCPVTNNFEFELLSSIFCKACGLTVFKREPSRYLSINIPQGMKDQNMSIQSSLDLFFRAEELEHRCERCLYNKSVALHKFGRLPRVIIV
HLKRYSFSESRIMNKDEQHIVISKYLRLSCHCNKNTKPPQPLLPNEHVKNLDLLRPLEELGSEILKLSSNSGRTSRSKVFPTVNIRSDKELEVQNGKRVSEVSSGSAQQEDPGKGANVVRSELTNETE
TIKHEKEYVLSDLDSGSISEERSQKCQEAEKCNKEALPQSCPKPSSQEQTENLGKPAVSHTQNGSLSSQGSSDSSKSPGCNDVFDKAKPTSKVEPQKLNQKEDNIYRLVSIINHIGNSPNGGHYINDA
FDFRKQSWFTYSDLQVTGIQEDLVYKARLSTGYVFFYMHNDIFEELLAKEAWSTSTSKG

hide sequence

Ensembl Acc Id:

ENSRNOP00000047375 ⟸ ENSRNOT00000047605

RefSeq Acc Id:	XP_038955531 ⟸ XM_039099603
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038955533 ⟸ XM_039099605
- Peptide Label:	isoform X1
- UniProtKB:	D4A5S1 (UniProtKB/TrEMBL), A6JMT7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000085992 ⟸ ENSRNOT00000116818

Protein Domains

USP

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A5S1-F1-model_v2	AlphaFold	D4A5S1	1-827	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-1042	BioCyc
Ensembl Genes	ENSRNOG00000029106	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000047605	ENTREZGENE
	ENSRNOT00000047605.6	UniProtKB/TrEMBL
	ENSRNOT00000116818	ENTREZGENE
	ENSRNOT00000116818.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.29.180	UniProtKB/TrEMBL
	Cysteine proteinases	UniProtKB/TrEMBL
InterPro	Papain_like_cys_pep_sf	UniProtKB/TrEMBL
	Pept_C19ubi-hydrolase_C_CS	UniProtKB/TrEMBL
	Peptidase_C19	UniProtKB/TrEMBL
	Peptidase_C19	UniProtKB/TrEMBL
	UCH/PAN2	UniProtKB/TrEMBL
	UCH_N	UniProtKB/TrEMBL
	USP37-like_PH_sf	UniProtKB/TrEMBL
KEGG Report	rno:302488	UniProtKB/TrEMBL
NCBI Gene	302488	ENTREZGENE
PANTHER	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE	UniProtKB/TrEMBL
	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 26	UniProtKB/TrEMBL
Pfam	UCH	UniProtKB/TrEMBL
	UCH_N	UniProtKB/TrEMBL
PhenoGen	Usp26	PhenoGen
PROSITE	UCH_2_1	UniProtKB/TrEMBL
	UCH_2_2	UniProtKB/TrEMBL
	UCH_2_3	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000029106	RatGTEx
Superfamily-SCOP	SSF54001	UniProtKB/TrEMBL
UniProt	A6JMT7	ENTREZGENE, UniProtKB/TrEMBL
	D4A5S1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Usp26	ubiquitin specific peptidase 26	LOC108353303	uncharacterized LOC108353303	Data merged from RGD:11428360	737654	PROVISIONAL
2016-08-02	LOC108353303	uncharacterized LOC108353303			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-04-30	Usp26	ubiquitin specific peptidase 26	Usp26_predicted	ubiquitin specific peptidase 26 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Usp26_predicted	ubiquitin specific peptidase 26 (predicted)	RGD1563443_predicted	similar to ubiquitin specific protease (predicted)	Symbol and Name updated	1299863	APPROVED
2006-03-07	RGD1563443_predicted	similar to ubiquitin specific protease (predicted)	LOC302488	similar to ubiquitin specific protease	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC302488	similar to ubiquitin specific protease			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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